chemblIds,Gene,Locus_name,CMR_GWAS_Phenotype(s),toxicityClass,country,Drug,Cardiovascular_Drug,actionType,mechanismOfAction,terms_drug,targetType,description_drug,approvedIndications,datasourceId,pgxCategory,pharmGKB_phenotypeText,directionality,variantRsId,isDirectTarget
CHEMBL1421,EPHA2,"ZBTB17, C1orf64, CLCNKA, SPEN","LVEDV, LVEDV_BSA, LVEF, LVESV, LVEDV_BSA, LVEDV, LVESV_BSA, RVEDV_BSA, RVEF, RVESV_BSA, RVESV","","",DASATINIB,No,INHIBITOR,Ephrin type-A receptor 2 inhibitor,"['hepatosplenic T-cell lymphoma', 'Hepatosplenic gamma/Delta T-cell lymphoma', 'HSTCL', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'Myelodysplastic/Myeloproliferative Neoplasm', 'myelodysplastic myeloproliferative disease', 'myeloproliferative/myelodysplastic disorders', 'myeloproliferative/myelodysplastic syndromes', 'myelodysplastic/myeloproliferative diseases', 'MDS/MPD', 'myelodysplastic/myeloproliferative disease', 'MDS-MPD', 'myelodysplastic/myeloproliferative disorder', 'myelodysplastic/myeloproliferative disorders', 'MPD-MDS', 'myelodysplastic myeloproliferative cancer', 'MDS/MPN', 'myelodysplastic/myeloproliferative neoplasms', 'MPD/MDS', 'myelodysplastic/myeloproliferative neoplasm', 'myelodysplastic/myeloproliferative Neoplasm', 'chronic myelogenous leukemia', 'chronic myeloid leukaemia', 'BCR-ABL Positive chronic myelogenous leukaemia', 'chronic myelogenous leukaemia (CML)', 'chronic myelogenous leukemia BCR-ABL1 Positive', 'chronic myeloid leukemia', 'BCR-ABL Positive chronic myelogenous leukemia', 'CML - chronic myelogenous leukemia', 'leukemia Philadelphia chromosome-positive resistant to imatinib Somatic mutation', 'chronic myelogenous leukemia (CML)', 'chronic granulocytic leukemia', 'chronic myelogenous leukemia BCR-ABL1 positive', 'CML', 'myeloid leukemia chronic', 'CML - chronic myelogenous leukaemia', 'hematopoeitic - chronic myelocytic leukaemia (CML)', 'chronic myelocytic leukaemia', 'leukemia chronic myeloid Philadelphia chromosome positive somatic', 'chronic myelocytic leukemia', 'chronic myelogenous leukaemia', 'chronic granulocytic leukaemia', 'hematopoeitic - chronic myelocytic leukemia (CML)', 'chronic myelogenous leukemias', 'leukemia chronic myeloid', 'leukemia chronic myeloid atypical', 'leukemia chronic myelogenous', 'myeloid leukemia', 'leukemia myeloid', 'leukaemia myelogenous', 'non-lymphoblastic leukemia', 'leukaemia granulocytic', 'leukemia granulocytic malignant', 'myelogenous leukaemia', 'leukaemia myeloid', 'non-lymphocytic leukemia', 'myelocytic leukemia', 'myeloid granulocytic leukemia', 'non-lymphocytic leukaemia', 'myelocytic leukaemia', 'non-lymphoblastic leukaemia', 'myeloid granulocytic leukaemia', 'myelogenous leukemia', 'leukemia myelogenous', 'leukemia granulocytic', 'Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'chronic lymphocytic leukemia', 'B-cell lymphocytic leukaemia', 'CLL', 'B-CLL', 'BCLL', 'chronic lymphogenous leukaemia', 'B cell lymphocytic leukemia', 'chronic lymphatic leukaemia', 'B cell CLL', 'B-cell lymphocytic leukemia', 'small lymphocytic lymphoma', 'B-cell chronic lymphoid leukaemia', 'lymphoplasmacytic leukaemia', 'B-cell chronic lymphocytic leukemia', 'B-cell chronic lymphogenous leukemia', 'B-cell chronic lymphogenous leukaemia', 'B-cell chronic lymphoid leukemia', 'B cell chronic lymphocytic leukaemia', 'chronic B-cell lymphocytic leukaemia', 'B cell lymphocytic leukaemia', 'chronic lymphocytic leukemia (CLL)', 'B-cell CLL', 'chronic lymphocytic leukaemia (CLL)', 'chronic lymphatic leukemia', 'chronic B-cell lymphocytic leukemia', 'B cell chronic lymphocytic leukemia', 'lymphoplasmacytic leukemia', 'hematopoeitic - chronic lymphocytic leukemia (CLL)', 'hematopoeitic - chronic lymphocytic leukaemia (CLL)', 'chronic lymphogenous leukemia', 'chronic lymphocytic leukaemia', 'leukemia chronic LYMPHOCYTIC', 'leukemia chronic lymphatic', 'leukemia lymphocytic chronic', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'T-cell large granular lymphocyte leukemia', 'large cell granular lymphogenous leukemia', 'T-cell large gran. lymph. leuk.', 'T-LGL', 'Tgamma large granular lymphocyte leukemia', 'T-cell large granular lymphocytic leukemia', 'large granular lymphocytic leukaemia', 'large granular lymphocytic leukemia', 'T-gamma lymphoproliferative disorder', 'T gamma lymphoproliferative disorder', 'leukemia large granular LYMPHOCYTIC malignant', 'T-LGL leukemia', 'large cell granular lymphoid leukemia', 'large cell granular lymphoid leukaemia', 'T-cell LGL leukemia', 'Tgamma large granular lymphocyte leukaemia', 'proliferation of large granular lymphocytes', 'T-LGL leukaemia', 'T-cell LGL leukaemia', 'T-cell large granular lymphocytic leukaemia', 'large cell granular lymphogenous leukaemia', 'large granular lymphocytosis', 'LGLL', 'LGL leukemia', 'large granular lymphocyte leukemia', 'LGL leukaemia', 'large granular lymphocyte leukaemia', 'TLGL', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'mesothelioma', 'Central Nervous System Neoplasm', 'tumour of central nervous system', 'tumour of CNS', 'tumor of central nervous system', 'CNS tumor', 'tumour of the CNS', 'tumour of the central nervous system', 'central nervous system neoplasm', 'neoplasm of central nervous system', 'brain/spinal cord tumour', 'tumor of the central nervous system', 'CNS tumour', 'central nervous system neoplasm (disease)', 'tumor of the CNS', 'CNS neoplasm', 'neoplasm of the central nervous system', 'neoplasm of CNS', 'tumor of CNS', 'central nervous system tumour', 'central nervous system tumor', 'brain/spinal cord tumor', 'Mantle cell lymphoma', 'classical mantle cell lymphoma', 'LCM', 'MCL', 'mantle cell lymphoma', 'mantle zone lymphoma', 'lymphoma mantle cell', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'hairy cell leukemia', 'HCL', 'leukemic reticuloendotheliosis', 'HCL-C', 'classic hairy cell leukaemia', 'classic hairy cell leukemia', 'neuroblastoma', '[M]Neuroblastoma NOS (morphologic abnormality)', 'neuroblastoma (Schwannian Stroma-poor)', '[M]Neuroblastoma NOS', 'neural Crest tumor malignant', 'NB - Neuroblastoma', 'neuroblastoma malignant', 'Central neuroblastoma', 'Neuroblastoma NOS', 'Sympathicoblastoma', 'neuroblastoma (Schwannian Stroma-Poor)', 'Neuroblastomas', 'neuroblastoma (morphologic abnormality)', '(neuroblastoma NOS) or (sympathicoblastoma)', 'neuroblastoma NOS (morphologic abnormality)', 'NB', 'follicular lymphoma', 'follicular centre cell lymphoma', """"""""follicular non-Hodgkin's lymphoma"""""""", 'lymphoma follicular malignant', 'follicle centre lymphoma', 'lymphoma follicular centre cell', 'follicular non-Hodgkin lymphoma', 'follicular center cell lymphoma', 'lymphoma follicular center cell', 'follicle center lymphoma', 'lymphoma follicular', 'leukemia', 'leukaemia (disease)', 'leukemias general', 'leukemias', 'leukemia (disease)', 'blood (leukemia)', 'leukemia disease', 'leukemia malignant', 'leukaemia NOS', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'MALT lymphoma', 'mucosa-associated lymphoid tissue lymphoma', 'Immunocytoma', 'MALToma', 'lymphoma MALT somatic', 'Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue', 'Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT-lymphoma)', 'Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue', 'Extranodal marginal zone B-cell lymphoma', 'lymphoma of mucosa-associated lymphoid tissue', 'MALT-lymphoma', 'mucosa-associated lymphatic tissue lymphoma', 'lymphoma mucosa-associated lymphoid type', 'extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma)', 'familial primary gastric lymphoma', 'gastric lymphoma primary', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'breast carcinoma', 'cancer breast', 'breast cancer', 'cancer of the breast', 'cancer of breast', 'breast cancer NOS', 'carcinoma of breast', 'mammary carcinoma', 'carcinoma of the breast', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'mycosis fungoides', 'mycosis fungoides (morphologic abnormality)', 'mycosis fungoides Alibert-Bazin type', 'mycosis fungoides of unspecified site', 'MF', 'mycosis fungoides NOS (morphologic abnormality)', 'cutaneous T-cell lymphoma/mycosis fungoides', 'mycosis fungoides unspecified site extranodal and solid organ sites', 'CTCL/ mycosis fungoides', 'mycosis fungoides lymphoma', 'Alibert-Bazin syndrome', 'classic mycosis fungoides', 'granuloma fungoides', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'lymphoma', """"""""lymphoma (Hodgkin's and non-Hodgkin's)"""""""", 'lymphoma (Hodgkin and non-Hodgkin)', 'lymphomatous', 'lymphoid cancer', 'malignant lymphoma', 'lymphoma malignant', 'MLYM', 'rhabdomyosarcoma', 'rhabdomyosarcoma malignant', 'rhabdomyosarcoma (disease)', 'metastatic melanoma', 'metastatic malignant melanoma', 'squamous cell carcinoma', 'squamous cell carcinoma NOS (morphologic abnormality)', 'epidermoid cell cancer', 'epidermoid carcinoma', 'malignant epidermoid cell neoplasm', 'malignant epidermoid cell tumour', 'carcinoma squamous cell malignant', 'malignant squamous cell tumor', 'malignant epidermoid cell tumor', 'malignant squamous cell neoplasm', 'malignant squamous cell tumour', 'squamous cell cancer', 'squamous carcinoma', 'SCC', 'squamous cell epithelioma', 'squamous cell carcinoma (morphologic abnormality)', 'childhood acute lymphoblastic leukemia', 'acute lymphoblastic leukaemia (ALL)', 'acute lymphoblastic leukemia (ALL)', 'paediatric acute lymphocytic leukaemia (ALL)', 'pediatric acute lymphoblastic leukemia', 'paediatric acute lymphogenous leukaemia', 'childhood ALL', 'pediatric acute lymphocytic leukemia', 'childhood acute lymphoid leukaemia', 'pediatric acute lymphogenous leukemia', 'paediatric acute lymphoblastic leukaemia', 'paediatric acute lymphoid leukaemia', 'childhood acute lymphogenous leukaemia', 'childhood acute lymphoid leukemia', 'paediatric ALL', 'pediatric acute lymphoid leukemia', 'paediatric acute lymphocytic leukaemia', 'childhood acute lymphogenous leukemia', 'childhood precursor lymphoblastic leukemia', 'childhood acute lymphocytic leukemia', 'childhood precursor lymphoblastic leukaemia', 'pediatric acute lymphocytic leukemia (ALL)', 'pediatric ALL', 'childhood acute lymphocytic leukaemia', 'small intestine lymphoma', 'small bowel lymphoma', 'lymphoma of small bowel', 'lymphoma of the small intestine', 'primary small intestinal lymphoma', 'small intestinal lymphoma', 'lymphoma of small intestine', 'lymphoma of the small bowel', 'adult B acute lymphoblastic leukemia', 'B acute lymphoblastic leukaemia', 'B acute lymphoblastic leukemia', 'adult B cell acute lymphocytic leukemia', 'adult B cell ALL', 'adult B-cell lymphocytic leukemia', 'B cell adult acute lymphoblastic leukaemia', 'adult precursor B-lymphoblastic leukaemia', 'adult B cell acute lymphoblastic leukemia', 'adult B acute lymphoblastic leukaemia', 'adult B-cell acute lymphoblastic leukaemia', 'B cell adult acute lymphoblastic leukemia', 'B-cell adult acute lymphocytic leukemia', 'B-cell childhood acute lymphoblastic leukaemia of adults', 'B-cell adult acute lymphoblastic leukemia', 'adult B-cell ALL', 'B cell adult acute lymphocytic leukemia', 'adult B-cell acute lymphocytic leukaemia', 'adult B-lymphoblastic leukemia', 'adult B-cell acute lymphoblastic leukemia', 'adult precursor B-lymphoblastic leukemia', 'B cell adult acute lymphocytic leukaemia', 'adult B-cell acute lymphocytic leukemia', 'B-cell adult ALL', 'adult B-lymphoblastic leukaemia', 'adult B-cell childhood acute lymphoblastic leukaemia', 'adult B cell acute lymphocytic leukaemia', 'B-cell adult acute lymphoblastic leukaemia', 'adult B cell acute lymphoblastic leukaemia', 'adult B-cell childhood acute lymphoblastic leukemia', 'B cell adult ALL', 'adult B-cell lymphocytic leukaemia', 'B-cell childhood acute lymphoblastic leukemia of adults', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'gliosarcoma', 'glioblastoma with a sarcomatous component', 'glioblastoma with sarcomatous component', 'sarcomatous glioblastoma', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'peritoneum cancer', 'peritoneal cancer', 'peritoneal cavity cancer', 'malignant peritoneal neoplasm', 'cancer of peritoneum', 'malignant peritoneum neoplasm', 'cancer of the peritoneum', 'malignant neoplasm of peritoneum', 'peritoneal neoplasm', 'biliary tract neoplasm', 'biliary tree neoplasm', 'tumor of biliary tree', 'neoplasm of biliary tree', 'biliary tree neoplasm (disease)', 'neoplasm of extrahepatic bile ducts', 'tumour of biliary tree', 'biliary tract neoplasm (disease)', 'biliary tree tumour', 'biliary tree tumor', 'tumour of the extrahepatic bile duct', 'adult acute lymphoblastic leukemia', 'adult acute lymphoid leukemia', 'adult precursor lymphoblastic leukaemia', 'adult acute lymphoid leukaemia', 'adult precursor lymphoblastic leukemia', 'adult acute lymphogenous leukemia', 'adult ALL', 'adult acute lymphogenous leukaemia', 'adult acute lymphocytic leukemia', 'adult acute lymphocytic leukaemia', 'Hodgkins lymphoma', 'Hodgkin lymphoma', """"""""Hodgkin's disease"""""""", """"""""Hodgkin's lymphoma"""""""", 'Hodgkin disease', """"""""Hodgkin's sarcoma"""""""", 'HL', 'stage II subdiaphragmatic Hodgkin lymphoma', 'stage I subdiaphragmatic Hodgkin lymphoma', """"""""lymphoma Hodgkin's"""""""", 'malignant glioma', 'glioma', 'neuroglial tumour', 'neuroglial tumor', 'malignant neuroglial neoplasm', 'glial cell tumour', 'glioma malignant', 'malignant glial tumor', 'high-grade glioma', 'glial cell tumor', 'malignant glial neoplasm', 'malignant neuroglial tumour', 'malignant glial tumour', 'high grade glioma', 'malignant neuroglial tumor', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'Splenic Marginal Zone Lymphoma', 'splenic marginal zone lymphoma', 'splenic lymphoma with circulating villous lymphocytes', 'marginal zone lymphoma of spleen', 'splenic marginal zone lymphoma with villous lymphocytes', 'SLVL', 'splenic marginal zone B-cell lymphoma with villous lymphocytes', 'marginal zone lymphoma of the spleen', 'splenic marginal zone B-cell lymphoma', 'SMZL', 'metastatic prostate cancer', 'prostate carcinoma metastatic', 'metastatic prostate carcinoma', 'prostate cancer metastatic', 'cholangiocarcinoma', 'bile duct cancer', 'intrahepatic bile duct cancer (cholangiocarcinoma)', 'cholangiocarcinoma malignant', 'CC', 'adult primary cholangiocellular carcinoma', 'Cholangiocellular carcinoma', 'cholangiocarcinoma intrahepatic and extrahepatic bile ducts (adenocarcinoma)', 'CCA', 'cholangiosarcoma', 'adult primary cholangiocarcinoma', 'Cholangiocar.- intra/extrahepatic', 'Burkitts lymphoma', """"""""malignant lymphoma Burkitt's type"""""""", """"""""Burkitt's tumor or lymphoma"""""""", """"""""Burkitt's tumour or lymphoma"""""""", 'small non-cleaved cell lymphoma', """"""""Burkitt's lymphoma"""""""", 'Burkitt lymphoma', 'burkitt lymphoma somatic', 'Burkitt lymphoma/leukemia', """"""""Burkitt's tumour"""""""", """"""""small non-cleaved cell lymphoma Burkitt's type"""""""", 'Burkitt lymphoma/leukaemia', """"""""Burkitt's tumor"""""""", 'BL', 'adult T-cell leukemia/lymphoma', 'adult T-cell leukaemia', 'T-cell leukemia of adults', 'ATLL', 'T-cell leukaemia of adults', 'adult T-cell leukemia', 'adult T cell lymphoma/leukemia', 'HTLV-I associated adult T-cell leukemia/lymphoma', 'adult T-cell lymphoma/leukemia', 'adult T-cell lymphoma', 'HTLV-1 associated adult T-cell lymphoma/leukemia', 'adult T-cell leukemia/lymphoma (HTLV-1 positive)', 'diffuse intrinsic pontine glioma', 'DIPG', 'diffuse midline glioma', 'infiltrative brainstem glioma', 'lymphoblastic lymphoma', 'precursor lymphoblastic lymphoma', 'lymphoma lymphoblastic malignant', 'precursor cell lymphoblastic lymphoma', 'lymphoma lymphoblastic', 'diffuse large B-cell lymphoma', 'DLBCL', 'core binding factor acute myeloid leukemia', 'CBF-AML', 'squamous cell lung carcinoma', 'epidermoid cell carcinoma of the lung', 'epidermoid cell lung carcinoma', 'lung squamous cell carcinoma', 'squamous cell carcinoma of lung', 'squamous cell lung cancer', 'squamous cell carcinoma of the lung', 'epidermoid cell carcinoma of lung', 'lymphoid neoplasm', 'lymphoid and plasmacytic tumour', 'lymphoid and plasmacytic neoplasm', 'lymphocytic tumor', 'lymphocytic tumour', 'lymphoid and plasmacytic tumor', 'lymphocytic and plasma cell tumor', 'lymphoid and plasma cell tumor', 'lymphocytic and plasmacytic neoplasm', 'lymphoid and plasma cell tumour', 'lymphocytic and plasma cell neoplasm', 'lymphocytic neoplasm', 'lymphoid tumour', 'lymphocytic and plasma cell tumour', 'lymphoid tumor', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'idiopathic pulmonary fibrosis', 'fibrocystic pulmonary dysplasia', 'cryptogenic fibrosing alveolitis', 'idiopathic pulmonary fibrosis familial', 'UIP', 'usual interstitial pneumonia', 'CFA', 'pulmonary fibrosis idiopathic', 'Hamman-rich disease', 'familial idiopathic pulmonary fibrosis', 'fibrosing alveolitis', 'interstitial pneumonitis usual', 'fibrosing alveolitis cryptogenic', 'IPF', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'systemic mastocytosis', 'Mast cell disease', 'systemic tissue Mast cell disease', 'SMCD - systemic mast cell disease', 'systemic tissue mast cell disease', 'Agressive systemic mastocytosis', 'systemic mast cell disease', 'systemic mastocytosis with associated hemotologic non-mast cell lineage disease (SM-AHNMD)', 'SM', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'therapy related acute myeloid leukemia and myelodysplastic syndrome', 'therapy-related AML and myelodysplastic syndrome', 'Secondary Acute myeloblastic Leukaemia', 'Secondary Acute granulocytic Leukemia', 'Secondary Acute granulocytic Leukaemia', 'Secondary AGL', 'secondary acute myeloid leukemia', 'secondary AML', 'Secondary Acute myeloid Leukemia (AML)', 'Secondary Acute myelocytic Leukaemia', 'Secondary Acute myelocytic Leukemia', 'Secondary Acute myeloid Leukaemia (AML)', 'secondary acute myeloid leukaemia', 'Secondary Acute myelogenous Leukemia', 'Secondary Acute myelogenous Leukaemia', 'Secondary Acute myeloblastic Leukemia', 'head and neck malignant neoplasia', 'head/neck neoplasm', 'tumour of head and neck', 'head and neck neoplasm', 'head and neck tumors', 'head and neck tumours', 'malignant tumor of the head and neck', 'malignant head and neck tumor', 'head and neck cancer', 'cancer of the head and neck', 'malignant neoplasm of the head and neck', 'malignant tumor of head and neck', 'malignant neoplasm of head and neck', 'malignant head and neck tumour', 'malignant craniocervical region neoplasm', 'cancer of craniocervical region', 'malignant neoplasm of craniocervical region', 'malignant tumour of head and neck', 'craniocervical region cancer', 'malignant tumour of the head and neck', 'malignant head and neck neoplasm', 'cancer of head and neck', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'major salivary gland cancer', 'malignant tumour of the major salivary gland', 'malignant tumour of major salivary gland', 'malignant tumor of major salivary gland', 'malignant neoplasm of major salivary gland', 'malignant tumor of the major salivary gland', 'malignant major salivary gland neoplasm', 'malignant major salivary gland tumour', 'cancer of major salivary gland', 'malignant neoplasm of the major salivary gland', 'malignant major salivary gland tumor', 'malignant neoplasm of major salivary glands', """"""""Sezary's disease"""""""", 'Sezary disease', 'Sezary lymphoma', 'CTCL / Sezary syndrome', 'cutaneous T-cell lymphoma/Sezary syndrome', 'SC)zary syndrome', 'Sézary syndrome', 'Sezary syndrome', 'Sézary lymphoma', 'SS', """"""""Sezary's lymphoma"""""""", 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'lung adenocarcinoma', 'adenocarcinoma of the lung', 'non-small cell lung adenocarcinoma', 'bronchogenic lung adenocarcinoma', 'nonsmall cell adenocarcinoma', 'LUAD', 'adenocarcinoma of lung', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'metastatic malignant neoplasm', 'malignant metastatic neoplasm', 'metastatic neoplasm malignant', 'metastatic cancer', 'Waldenstrom macroglobulinemia', 'lymphoplasmacytic lymphoma with IgM gammopathy', """"""""Waldenstrom's macroglobulinemia"""""""", 'Waldenström macroglobulinemia', """"""""Waldenstrom's macroglobulinaemia"""""""", 'macroglobulinemia of Waldenstrom', """"""""Waldenstroem's macroglobulinemia"""""""", """"""""Waldenstrom's syndrome"""""""", 'Pineoblastoma', 'primitive neuroectodermal tumour of the pineal gland', 'pineal gland primitive neuroectodermal tumor', 'pineal primitive neuroectodermal tumor', 'primitive neuroectodermal tumour of pineal gland', 'pineoblastoma (WHO grade IV)', 'primitive neuroectodermal neoplasm of pineal gland', 'pineal primitive neuroectodermal tumour', 'pineoblastoma malignant', 'pineal gland primitive neuroectodermal tumour', 'pineal PNET', 'pineal primitive neuroectodermal neoplasm', 'pineoblastoma', 'pineal gland PNET', 'primitive neuroectodermal tumor of the pineal gland', 'primitive neuroectodermal tumor of pineal gland', 'primitive neuroectodermal neoplasm of the pineal gland', 'PNET of the pineal gland', 'PNET of pineal gland', 'pineal gland primitive neuroectodermal neoplasm', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'myelodysplastic syndrome', 'MDS', 'myelodysplastic neoplasm', 'MDS unclassifiable', 'myelodysplastic syndrome somatic', 'myelodysplasia', 'oligoblastic leukaemia', 'myelodysplastic syndromes', 'MDS-U', 'dysmyelopoietic syndrome', 'oligoblastic leukemia', 'preleukemia', 'myelodysplastic syndrome/neoplasm', 'hematopoeitic - myelodysplastic syndrome (MDS)', 'smouldering leukaemia', 'myelodysplastic syndrome unclassifiable', 'smoldering leukemia', 'myelodysplastic syndrome susceptibility to', 'salivary gland adenoid cystic carcinoma', 'adenoid cystic carcinoma (morphologic abnormality)', 'adenoid cystic cancer', 'adenoid cystic carcinoma of the salivary gland', 'cylindroma (morphologic abnormality)', 'saliva-secreting gland adenoid cystic carcinoma', 'adenoid cystic carcinoma of salivary gland', 'salivary gland adenoid cystic cancer', 'non-Hodgkins lymphoma', """"""""non-Hodgkin's lymphoma"""""""", 'NHL', 'non-Hodgkin lymphoma', """"""""non-Hodgkin's lymphoma (NHL)"""""""", 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'adult T acute lymphoblastic leukemia', 'T cell adult ALL', 'T Acute Lymphoblastic Leukemia', 'T-cell adult ALL', 'adult acute lymphoblastic leukemia of T cell', 'adult precursor T lymphoblastic leukaemia', 'T-cell adult acute lymphocytic leukemia', 'T Acute Lymphoblastic Leukaemia', 'acute Adult T-cell Leukem","","","","","","",,"",
CHEMBL1946170,EPHA2,"ZBTB17, C1orf64, CLCNKA, SPEN","LVEDV, LVEDV_BSA, LVEF, LVESV, LVEDV_BSA, LVEDV, LVESV_BSA, RVEDV_BSA, RVEF, RVESV_BSA, RVESV","",United States,REGORAFENIB,No,INHIBITOR,Ephrin type-A receptor 2,"['biliary tract cancer', 'cancer of biliary tree', 'biliary tree cancer', 'malignant tumour of biliary tract', 'malignant neoplasm of biliary tree', 'malignant tumor of biliary tract', 'malignant biliary tree neoplasm', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'ovarian neoplasm', 'OVARY NEOPL', 'Ovary Neoplasm', 'ovarian tumour', 'ovary neoplasm (disease)', 'Neoplasm Ovary', 'Cancer of Ovary', 'ovarian tumors', 'neoplasm of ovary', 'ovary tumor', 'Neoplasms Ovary', 'tumour of the ovary', 'neoplasm of the ovary', 'Ovary Neoplasms', 'ovarian tumours', 'tumor of ovary', 'ovarian tumor', 'Neoplasm Ovarian', 'tumour of ovary', 'Neoplasms Ovarian', 'OVARIAN NEOPL', 'NEOPL OVARIAN', 'ovary tumour', 'tumor of the ovary', 'Ovarian Neoplasms', 'ovary neoplasm', 'angiosarcoma', 'vascular sarcoma', 'hemangiosarcoma malignant', 'sarcoma of blood vessel', 'malignant hemangioendothelioma', 'hemangiosarcoma', 'blood vessel sarcoma', 'angiosarcoma (disease)', 'malignant angioendothelioma', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'intrahepatic cholangiocarcinoma', 'peripheral cholangiocarcinoma', 'cholangiocarcinoma intrahepatic malignant', 'intrahepatic Cholangiocellular carcinoma', 'intrahepatic bile duct cancer (cholangiocarcinoma)', 'intrahepatic carcinoma of the bile duct', 'intrahepatic carcinoma of bile duct', 'intrahepatic bile duct carcinoma', 'ICC', 'intrahepatic cholangiocarcinoma (bile duct cancer)', 'IHCH', 'malignant renal pelvis neoplasm', 'malignant tumour of renal pelvis', 'malignant renal pelvis tumor', 'malignant tumour of the renal pelvis', 'malignant tumor of the renal pelvis', 'malignant tumor of renal pelvis', 'malignant renal pelvis tumour', 'renal pelvis cancer', 'malignant neoplasm of renal pelvis', 'malignant neoplasm of the renal pelvis', 'cancer of renal pelvis', 'ovarian carcinoma', 'ovarian cancer', 'ovarian epithelial cancer', 'carcinoma of ovary', 'ovary carcinoma', 'EOS', 'epithelial ovarian cancer', 'carcinoma of the ovary', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'bile duct carcinoma', 'bile duct cancer', 'bile duct cancer (including cholangiocarcinoma)', 'carcinoma of bile duct', 'gastric cancer', 'gastric neoplasm', 'malignant tumor of lesser curve of stomach', 'malignant tumour of body of stomach', 'malignant neoplasm of stomach', 'gastric cancer risk after h. pylori infection', 'malignant neoplasm of lesser curve of stomach', 'malignant gastric tumour', 'malignant gastric neoplasm', 'malignant tumour of greater curve of stomach', 'Ca lesser curvature - stomach', 'malignant stomach neoplasm', 'malignant tumor of greater curve of stomach', 'malignant tumor of body of stomach', 'malignant tumour of the stomach', 'malignant tumour of stomach', 'malignant tumor of the stomach', 'gastric cancer somatic', 'malignant tumour of lesser curve of stomach', 'malignant neoplasm of the stomach', 'malignant tumor of stomach', 'cancer of stomach', 'malignant gastric tumor', 'stomach cancer', 'Ca body - stomach', 'ca greater curvature of stomach', 'malignant neoplasm of body of stomach', 'gastric cancer intestinal', 'primary peritoneal carcinoma', 'EOPPC', 'serous surface papillary carcinoma', 'primary peritoneal cancer', 'Extra-ovarian primary peritoneal carcinoma', 'primary peritoneal serous carcinoma', 'PPC', 'primary peritoneal carcinoma (disease)', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'colorectal adenocarcinoma', 'colorectum adenocarcinoma', 'adenocarcinoma of the large bowel', 'colorectal (colon or rectal) adenocarcinoma', 'adenocarcinoma of large bowel', 'large intestine adenocarcinoma', 'adenocarcinoma of the large intestine', 'large bowel adenocarcinoma', 'adenocarcinoma of large intestine', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'liposarcoma', 'lip sarcoma', 'liposarcoma malignant', 'sarcoma of lip', 'thyroid cancer', 'neoplasm of thyroid gland', 'thyroid gland neoplasm', 'thyroid gland cancer', 'malignant tumor of the thyroid gland', 'malignant neoplasm of the thyroid gland', 'malignant thyroid tumor', 'malignant thyroid neoplasm', 'malignant neoplasm of the thyroid', 'malignant tumor of the thyroid', 'malignant tumor of thyroid', 'malignant thyroid gland neoplasm', 'cancer of thyroid gland', 'malignant thyroid gland tumour', 'malignant thyroid tumour', 'malignant tumour of thyroid', 'malignant tumour of the thyroid gland', 'malignant thyroid gland tumor', 'malignant neoplasm of thyroid gland', 'malignant tumour of thyroid gland', 'malignant tumor of thyroid gland', 'malignant tumour of the thyroid', 'malignant neoplasm of thyroid', 'macular degeneration', 'macula retinal degeneration', 'macular degeneration of retina', 'macula lutea retinal degeneration', 'retinal degeneration of macula lutea', 'colorectal neoplasm', 'colorectal tumour', 'tumor of the large bowel', 'colorectum tumour', 'large intestine tumor', 'neoplasm of colorectum', 'tumor of colorectum', 'large intestine neoplasm', 'tumor of large bowel', 'large bowel tumour', 'colorectum neoplasm (disease)', 'neoplasm of large bowel', 'large bowel tumor', 'large intestinal neoplasm', 'large intestine tumour', 'colorectum neoplasm', 'colorectum tumor', 'tumour of the large bowel', 'colorectal tumor', 'tumour of colorectum', 'tumour of large bowel', 'large bowel neoplasm', 'neoplasm of the large bowel', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'soft tissue sarcoma', 'malignant soft tissue tumor', 'malignant soft tissue tumour', 'malignant mesenchymal tumor', 'sarcoma of the soft tissue', 'soft part sarcoma', 'sarcoma of soft tissue', 'malignant mesenchymal tumour', 'connective tissue sarcoma', 'non-Rhabdo. soft tissue sarcoma', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'rhabdomyosarcoma', 'rhabdomyosarcoma malignant', 'rhabdomyosarcoma (disease)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'malignant tumour of large intestine', 'colon cancer advanced somatic', 'malignant colorectal tumor', 'malignant neoplasm of large intestine', 'malignant colorectal neoplasm', 'malignant tumour of the large intestine', 'malignant tumour of large bowel', 'malignant large intestine neoplasm', 'malignant tumor of the large intestine', 'malignant neoplasm of large bowel', 'colorectal cancer somatic', 'malignant tumour of the large bowel', 'malignant large intestine tumor', 'malignant large bowel neoplasm', 'malignant large bowel tumor', 'malignant tumor of large intestine', 'cancer of colorectum', 'malignant large bowel tumour', 'colorectal cancer with chromosomal instability somatic', 'malignant neoplasm of the large intestine', 'colon cancer somatic', 'colorectal cancer susceptibility to autosomal dominant somatic mutation', 'malignant neoplasm of colorectum', 'malignant large intestine tumour', 'malignant tumor of large bowel', 'colorectum cancer', 'malignant colorectum neoplasm', 'colorectal cancer autosomal dominant somatic mutation', 'malignant neoplasm of the large bowel', 'malignant tumor of the large bowel', 'malignant colorectal tumour', 'colon cancer susceptibility to autosomal dominant somatic mutation', 'Digestive System Carcinoma', 'gastrointestinal carcinoma (disease)', 'gastrointestinal system carcinoma', 'carcinoma of digestive system', 'digestive system carcinoma', 'gastrointestinal carcinoma', 'carcinoma of the gastrointestinal system', 'cholangiocarcinoma', 'cholangiocarcinoma malignant', 'CC', 'adult primary cholangiocellular carcinoma', 'Cholangiocellular carcinoma', 'cholangiocarcinoma intrahepatic and extrahepatic bile ducts (adenocarcinoma)', 'CCA', 'cholangiosarcoma', 'adult primary cholangiocarcinoma', 'Cholangiocar.- intra/extrahepatic', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'osteosarcoma', 'bone tissue neoplasm', 'osteogenic sarcoma', 'osteosarcoma malignant', 'OS', 'osteosarcoma (disease)', 'sarcoma of osteoid', 'osteoid sarcoma', 'colon adenocarcinoma', 'colonic adenocarcinoma', 'adenocarcinoma of colon', 'adenocarcinoma - colon', 'adenocarcinoma of the colon', 'COAD', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'Malignant Bone Neoplasm', 'osseous tumor', 'bone neoplasm', 'bone tumor', 'osseous tumour', 'bone tumour', 'malignant neoplasm of skeletal element', 'malignant bone neoplasm', 'skeletal element cancer', 'CA - bone cancer', 'cancer of skeletal element', 'malignant osseous tumour', 'malignant neoplasm of bone', 'malignant osseous neoplasm', 'malignant bone tumour', 'malignant osseous tumor', 'malignant tumor of bone', 'osseous cancer', 'cancer of bone', 'malignant skeletal element neoplasm', 'malignant tumor of the bone', 'malignant tumour of the bone', 'malignant bone tumor', 'malignant tumour of bone', 'bone cancer', 'malignant neoplasm of the bone', 'cancer of the bone', 'gastrointestinal stromal tumor', 'gastrointestinal stromal tumor familial isolated cases', 'gastrointestinal stromal sarcoma', 'gant', 'stromal tumor of gastrointestinal tract', 'gastrointestinal stromal tumor isolated cases', 'stromal tumour of gastrointestinal tract', 'gist', 'gastrointestinal stromal tumour (gist)', 'gastrointestinal stromal neoplasm', 'gastrointestinal stromal tumor (gist)', 'gastrointestinal stromal tumors', 'gastrointestinal stromal tumours', 'fallopian tube cancer', 'tumor of the fallopian tube', 'tumour of the fallopian tube', 'malignant tumour of the fallopian tube', 'malignant tumor of fallopian tubes', 'malignant tubal tumor', 'cancer of fallopian tubes', 'fallopian tube malignant neoplasm', 'tumor fallopian tube malignant', 'malignant tumour of fallopian tube', 'malignant fallopian tube neoplasm', 'fallopian tube malignant tumour', 'malignant tumor of fallopian tube', 'malignant tumor of the fallopian tube', 'malignant neoplasm of uterine tube', 'cancer of fallopian tube', 'malignant neoplasm of the fallopian tube', 'malignant tumour of fallopian tubes', 'neoplasm fallopian tube malignant', 'malignant neoplasm of fallopian tube', 'malignant fallopian tube tumor', 'tubal cancer', 'malignant fallopian tube tumour', 'fallopian tube malignant tumor', 'malignant tubal tumour', 'metastatic colorectal cancer', 'adenoid cystic carcinoma', 'cylindroid adenocarcinoma', 'adenoid cystic cancer', 'adenocystic carcinoma', 'cylindroma', 'cribriform carcinoma', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'Vascular endothelial growth factor receptor 2', 'KDR', 'FLK1', 'VEGFR2', 'CD309', 'VEGFR-2', 'FLK-1', 'VEGFR', 'Fetal liver kinase 1', 'Kinase insert domain receptor', 'Protein-tyrosine kinase receptor flk-1', 'vascular endothelial growth factor receptor 2', 'fetal liver kinase 1', 'fetal liver kinase-1', 'kinase insert domain receptor (a type III receptor tyrosine kinase)', 'protein-tyrosine kinase receptor Flk-1', 'soluble VEGFR2', 'tyrosine kinase growth factor receptor', 'kinase insert domain receptor', 'Proto-oncogene tyrosine-protein kinase receptor Ret', 'Soluble RET kinase fragment', 'Extracellular cell-membrane anchored RET cadherin 120 kDa fragment', 'RET', 'CDHF12', 'CDHR16', 'PTC', 'RET51', 'Cadherin family member 12', 'Proto-oncogene c-Ret', 'cadherin-related family member 16', 'RET receptor tyrosine kinase', 'rearranged during transfection', 'HSCR1', 'MEN2A', 'MEN2B', 'MTC1', 'RET-ELE1', 'proto-oncogene tyrosine-protein kinase receptor Ret', 'cadherin family member 12', 'proto-oncogene c-Ret', 'ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1 Hirschsprung disease)', 'ret proto-oncogene', 'Fibroblast growth factor receptor 2', 'FGFR2', 'BEK', 'KGFR', 'KSAM', 'CD332', 'FGFR-2', 'CEK3', 'TK14', 'TK25', 'ECT1', 'K-SAM', 'K-sam', 'Keratinocyte growth factor receptor', 'Crouzon syndrome', 'Pfeiffer syndrome', 'BBDS', 'BFR-1', 'CFD1', 'JWS', 'fibroblast growth factor receptor 2', 'BEK fibroblast growth factor receptor', 'bacteria-expressed kinase', 'keratinocyte growth factor receptor', 'protein tyrosine kinase receptor like 14', 'Vascular endothelial growth factor receptor 3', 'FLT4', 'VEGFR3', 'VEGFR-3', 'FLT-4', 'PCL', 'Fms-like tyrosine kinase 4', 'Tyrosine-protein kinase receptor FLT4', 'vascular endothelial growth factor receptor 3', 'VEGF receptor-3', 'Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4', 'primary congenital lymphedema', 'CHTD7', 'FLT41', 'LMPH1A', 'LMPHM1', 'fms related tyrosine kinase 4', 'fms-like tyrosine kinase 4', 'tyrosine-protein kinase receptor FLT4', 'fms related receptor tyrosine kinase 4', 'Mitogen-activated protein kinase 11', 'MAPK11', 'PRKM11', 'SAPK2', 'SAPK2B', 'MAP kinase 11', 'MAPK 11', 'MAP kinase p38 beta', 'p38b', 'SAPK2b', 'p38-2', 'p38Beta', 'Mitogen-activated protein kinase p38 beta', 'Stress-activated protein kinase 2b', 'P38B', 'P38BETA2', 'mitogen-activated protein kinase 11', 'mitogen-activated protein kinase p38 beta', 'mitogen-activated protein kinase p38-2', 'stress-activated protein kinase-2', 'stress-activated protein kinase-2b', 'Angiopoietin-1 receptor', 'TEK', 'TIE2', 'VMCM', 'VMCM1', 'CD202b', 'hTIE2', 'TIE-2', 'Endothelial tyrosine kinase', 'Tunica interna endothelial cell kinase', 'Tyrosine kinase with Ig and EGF homology domains-2', 'Tyrosine-protein kinase receptor TEK', 'Tyrosine-protein kinase receptor TIE-2', 'p140 TEK', 'angiopoietin-1 receptor', 'CD202B', 'GLC3E', 'TEK tyrosine kinase endothelial', 'endothelial tyrosine kinase', 'tunica interna endothelial cell kinase', 'tyrosine kinase with Ig and EGF homology domains-2', 'tyrosine-protein kinase receptor TEK', 'tyrosine-protein kinase receptor TIE-2', 'TEK receptor tyrosine kinase', 'Platelet-derived growth factor receptor beta', 'PDGFRB', 'PDGFR', 'PDGFR1', 'CD140b', 'PDGF-R-beta', 'PDGFR-beta', 'PDGFR-1', 'JTK12', 'Beta platelet-derived growth factor receptor', 'Beta-type platelet-derived growth factor receptor', 'CD140 antigen-like family member B', 'Platelet-derived growth factor receptor 1', 'CD140B', 'IBGC4', 'IMF1', 'KOGS', 'PENTT', 'platelet-derived growth factor receptor beta', 'Activated tyrosine kinase PDGFRB', 'NDEL1-PDGFRB', 'beta-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 1', 'platelet-derived growth factor receptor beta polypeptide', 'platelet derived growth factor receptor beta', 'Ephrin type-A receptor 2', 'EPHA2', 'ECK', 'Epithelial cell kinase', 'Tyrosine-protein kinase receptor ECK', 'ARCC2', 'CTPA', 'CTPP1', 'CTRCT6', 'ephrin type-A receptor 2', 'epithelial cell receptor protein tyrosine kinase', 'tyrosine-protein kinase receptor ECK', 'EPH receptor A2', 'Mast/stem cell growth factor receptor Kit', 'KIT', 'SCFR', 'CD117', 'PBT', 'C-Kit', 'Piebald trait protein', 'Proto-oncogene c-Kit', 'Tyrosine-protein kinase Kit', 'p145 c-kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog', 'mast/stem cell growth factor receptor Kit', 'MASTC', 'c-Kit protooncogene', 'piebald trait protein', 'proto-oncogene c-Kit', 'proto-oncogene tyrosine-protein kinase Kit', 'tyrosine-protein kinase Kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein', 'KIT proto-oncogene receptor tyrosine kinase', 'Platelet-derived growth factor receptor alpha', 'PDGFRA', 'PDGFR2', 'RHEPDGFRA', 'CD140a', 'PDGF-R-alpha', 'PDGFR-alpha', 'PDGFR-2', 'GAS9', 'Alpha platelet-derived growth factor receptor', 'Alpha-type platelet-derived growth factor receptor', 'CD140 antigen-like family member A', 'CD140a antigen', 'Platelet-derived growth factor alpha receptor', 'Platelet-derived growth factor receptor 2', 'CD140A', 'platelet-derived growth factor receptor alpha', 'alpha-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 2', 'platelet-derived growth factor receptor alpha polypeptide', 'platelet derived growth factor receptor alpha', 'Tyrosine-protein kinase ABL1', 'ABL1', 'ABL', 'JTK7', 'c-ABL', 'p150', 'Abelson murine leukemia viral oncogene homolog 1', 'Abelson tyrosine-protein kinase 1', 'Proto-oncogene c-Abl', 'BCR-ABL', 'CHDSKM', 'bcr/abl', 'c-ABL1', 'v-abl', 'tyrosine-protein kinase ABL1', 'ABL protooncogene 1 nonreceptor tyrosine kinase', 'BCR-ABL1 p190', 'BCR/ABL e8a2 fusion', 'BCR/ABL1 e1a2 fusion protein', 'bcr/c-abl oncogene protein', 'c-abl oncogene 1 receptor tyrosine kinase', 'proto-oncogene c-Abl', 'proto-oncogene tyrosine-protein kinase ABL1', 'v-abl Abelson murine leukemia viral oncogene homolog 1', 'ABL proto-oncogene 1 non-receptor tyrosine kinase', 'Vascular endothelial growth factor receptor 1', 'FLT1', 'FLT', 'FRT', 'VEGFR1', 'VEGFR-1', 'FLT-1', 'Fms-like tyrosine kinase 1', 'Tyrosine-protein kinase FRT', 'Tyrosine-protein kinase receptor FLT', 'Vascular permeability factor receptor', 'vascular endothelial growth factor receptor 1', 'vascular permeability factor receptor', 'fms related tyrosine kinase 1', 'fms-like tyrosine kinase 1', 'fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)', 'tyrosine-protein kinase FRT', 'tyrosine-protein kinase receptor FLT', 'fms related receptor tyrosine kinase 1', 'Fibroblast growth factor receptor 1', 'FGFR1', 'BFGFR', 'CEK', 'FGFBR', 'FLG', 'FLT2', 'HBGFR', 'CD331', 'FGFR-1', 'bFGF-R-1', 'FLT-2', 'H2', 'H3', 'H4', 'H5', 'N-SAM', 'Basic fibroblast growth factor receptor 1', 'Fms-like tyrosine kinase 2', 'N-sam', 'Proto-oncogene c-Fgr', 'ECCL', 'HH2', 'HRTFDS', 'KAL2', 'OGD', 'fibroblast growth factor receptor 1', 'FGFR1/PLAG1 fusion', 'FMS-like tyrosine kinase 2', 'basic fibroblast growth factor receptor 1', 'fms-related tyrosine kinase 2', 'heparin-binding growth factor receptor', 'hydroxyaryl-protein kinase', 'proto-oncogene c-Fgr', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'Tyrosine-protein kinase FRK', 'FRK', 'PTK5', 'RAK', 'GTK', 'FYN-related kinase', 'Nuclear tyrosine protein kinase RAK', 'Protein-tyrosine kinase 5', 'tyrosine-protein kinase FRK', 'PTK5 protein tyrosine kinase 5', 'fyn-related kinase', 'nuclear tyrosine protein kinase RAK', 'protein-tyrosine kinase 5', 'fyn related Src family tyrosine kinase', 'Discoidin domain-containing receptor 2', 'DDR2', 'NTRKR3', 'TKT', 'TYRO10', 'CD167b', 'Discoidin domain receptor 2', 'CD167 antigen-like family member B', 'Discoidin domain-containing receptor tyrosine kinase 2', 'Neurotrophic tyrosine kinase receptor-related 3', 'Receptor protein-tyrosine kinase TKT', 'Tyrosine-protein kinase TYRO10', 'MIG20a', 'WRCN', 'discoidin domain-containing receptor 2', 'cell migration-inducing protein 20', 'discoidin domain receptor 2', 'discoidin domain receptor family member 2', 'discoidin domain-containing receptor tyrosine kinase 2', 'migration-inducing gene 16 protein', 'neurotrophic tyrosine kinase receptor related 3', 'receptor protein-tyrosine kinase TKT', 'tyrosine-protein kinase TYRO10', 'discoidin domain receptor tyrosine kinase 2', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'High affinity nerve growth factor receptor', 'NTRK1', 'MTC', 'TRK', 'TRKA', 'Trk-A', 'Neurotrophic tyrosine kinase receptor type 1', 'TRK1-transforming tyrosine kinase protein', 'Tropomyosin-related kinase A', 'Tyrosine kinase receptor', 'Tyrosine kinase receptor A', 'gp140trk', 'p140-TrkA', 'high affinity nerve growth factor receptor', 'tropomyosin receptor kinase A', 'TRK1', 'Oncogene TRK', 'neurotrophic tyrosine kinase receptor type 1', 'tropomyosin-related kinase A', 'tyrosine kinase receptor A', 'neurotrophic receptor tyrosine kinase 1', 'carcinoma', 'endocrine system disease', 'cancer or benign tumor', 'gastrointestinal disease', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'pancreas disease', 'reproductive system or breast disease', 'cardiovascular disease', 'nervous system disease', 'urinary system disease', 'integumentary system disease', 'musculoskeletal or connective tissue disease', 'disorder of visual system', 'hematologic disease', 'immune system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2012 and has 6 approved and 30 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0000616', 'EFO_0000365', 'MONDO_0004992', 'EFO_0004142', 'MONDO_0005575', 'EFO_1001951']",pharmgkb,toxicity,decreased risk of drug toxicity,,rs4864950,TRUE
CHEMBL1946170,EPHA2,"ZBTB17, C1orf64, CLCNKA, SPEN","LVEDV, LVEDV_BSA, LVEF, LVESV, LVEDV_BSA, LVEDV, LVESV_BSA, RVEDV_BSA, RVEF, RVESV_BSA, RVESV","",United States,REGORAFENIB,No,INHIBITOR,Ephrin type-A receptor 2,"['biliary tract cancer', 'cancer of biliary tree', 'biliary tree cancer', 'malignant tumour of biliary tract', 'malignant neoplasm of biliary tree', 'malignant tumor of biliary tract', 'malignant biliary tree neoplasm', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'ovarian neoplasm', 'OVARY NEOPL', 'Ovary Neoplasm', 'ovarian tumour', 'ovary neoplasm (disease)', 'Neoplasm Ovary', 'Cancer of Ovary', 'ovarian tumors', 'neoplasm of ovary', 'ovary tumor', 'Neoplasms Ovary', 'tumour of the ovary', 'neoplasm of the ovary', 'Ovary Neoplasms', 'ovarian tumours', 'tumor of ovary', 'ovarian tumor', 'Neoplasm Ovarian', 'tumour of ovary', 'Neoplasms Ovarian', 'OVARIAN NEOPL', 'NEOPL OVARIAN', 'ovary tumour', 'tumor of the ovary', 'Ovarian Neoplasms', 'ovary neoplasm', 'angiosarcoma', 'vascular sarcoma', 'hemangiosarcoma malignant', 'sarcoma of blood vessel', 'malignant hemangioendothelioma', 'hemangiosarcoma', 'blood vessel sarcoma', 'angiosarcoma (disease)', 'malignant angioendothelioma', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'intrahepatic cholangiocarcinoma', 'peripheral cholangiocarcinoma', 'cholangiocarcinoma intrahepatic malignant', 'intrahepatic Cholangiocellular carcinoma', 'intrahepatic bile duct cancer (cholangiocarcinoma)', 'intrahepatic carcinoma of the bile duct', 'intrahepatic carcinoma of bile duct', 'intrahepatic bile duct carcinoma', 'ICC', 'intrahepatic cholangiocarcinoma (bile duct cancer)', 'IHCH', 'malignant renal pelvis neoplasm', 'malignant tumour of renal pelvis', 'malignant renal pelvis tumor', 'malignant tumour of the renal pelvis', 'malignant tumor of the renal pelvis', 'malignant tumor of renal pelvis', 'malignant renal pelvis tumour', 'renal pelvis cancer', 'malignant neoplasm of renal pelvis', 'malignant neoplasm of the renal pelvis', 'cancer of renal pelvis', 'ovarian carcinoma', 'ovarian cancer', 'ovarian epithelial cancer', 'carcinoma of ovary', 'ovary carcinoma', 'EOS', 'epithelial ovarian cancer', 'carcinoma of the ovary', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'bile duct carcinoma', 'bile duct cancer', 'bile duct cancer (including cholangiocarcinoma)', 'carcinoma of bile duct', 'gastric cancer', 'gastric neoplasm', 'malignant tumor of lesser curve of stomach', 'malignant tumour of body of stomach', 'malignant neoplasm of stomach', 'gastric cancer risk after h. pylori infection', 'malignant neoplasm of lesser curve of stomach', 'malignant gastric tumour', 'malignant gastric neoplasm', 'malignant tumour of greater curve of stomach', 'Ca lesser curvature - stomach', 'malignant stomach neoplasm', 'malignant tumor of greater curve of stomach', 'malignant tumor of body of stomach', 'malignant tumour of the stomach', 'malignant tumour of stomach', 'malignant tumor of the stomach', 'gastric cancer somatic', 'malignant tumour of lesser curve of stomach', 'malignant neoplasm of the stomach', 'malignant tumor of stomach', 'cancer of stomach', 'malignant gastric tumor', 'stomach cancer', 'Ca body - stomach', 'ca greater curvature of stomach', 'malignant neoplasm of body of stomach', 'gastric cancer intestinal', 'primary peritoneal carcinoma', 'EOPPC', 'serous surface papillary carcinoma', 'primary peritoneal cancer', 'Extra-ovarian primary peritoneal carcinoma', 'primary peritoneal serous carcinoma', 'PPC', 'primary peritoneal carcinoma (disease)', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'colorectal adenocarcinoma', 'colorectum adenocarcinoma', 'adenocarcinoma of the large bowel', 'colorectal (colon or rectal) adenocarcinoma', 'adenocarcinoma of large bowel', 'large intestine adenocarcinoma', 'adenocarcinoma of the large intestine', 'large bowel adenocarcinoma', 'adenocarcinoma of large intestine', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'liposarcoma', 'lip sarcoma', 'liposarcoma malignant', 'sarcoma of lip', 'thyroid cancer', 'neoplasm of thyroid gland', 'thyroid gland neoplasm', 'thyroid gland cancer', 'malignant tumor of the thyroid gland', 'malignant neoplasm of the thyroid gland', 'malignant thyroid tumor', 'malignant thyroid neoplasm', 'malignant neoplasm of the thyroid', 'malignant tumor of the thyroid', 'malignant tumor of thyroid', 'malignant thyroid gland neoplasm', 'cancer of thyroid gland', 'malignant thyroid gland tumour', 'malignant thyroid tumour', 'malignant tumour of thyroid', 'malignant tumour of the thyroid gland', 'malignant thyroid gland tumor', 'malignant neoplasm of thyroid gland', 'malignant tumour of thyroid gland', 'malignant tumor of thyroid gland', 'malignant tumour of the thyroid', 'malignant neoplasm of thyroid', 'macular degeneration', 'macula retinal degeneration', 'macular degeneration of retina', 'macula lutea retinal degeneration', 'retinal degeneration of macula lutea', 'colorectal neoplasm', 'colorectal tumour', 'tumor of the large bowel', 'colorectum tumour', 'large intestine tumor', 'neoplasm of colorectum', 'tumor of colorectum', 'large intestine neoplasm', 'tumor of large bowel', 'large bowel tumour', 'colorectum neoplasm (disease)', 'neoplasm of large bowel', 'large bowel tumor', 'large intestinal neoplasm', 'large intestine tumour', 'colorectum neoplasm', 'colorectum tumor', 'tumour of the large bowel', 'colorectal tumor', 'tumour of colorectum', 'tumour of large bowel', 'large bowel neoplasm', 'neoplasm of the large bowel', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'soft tissue sarcoma', 'malignant soft tissue tumor', 'malignant soft tissue tumour', 'malignant mesenchymal tumor', 'sarcoma of the soft tissue', 'soft part sarcoma', 'sarcoma of soft tissue', 'malignant mesenchymal tumour', 'connective tissue sarcoma', 'non-Rhabdo. soft tissue sarcoma', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'rhabdomyosarcoma', 'rhabdomyosarcoma malignant', 'rhabdomyosarcoma (disease)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'malignant tumour of large intestine', 'colon cancer advanced somatic', 'malignant colorectal tumor', 'malignant neoplasm of large intestine', 'malignant colorectal neoplasm', 'malignant tumour of the large intestine', 'malignant tumour of large bowel', 'malignant large intestine neoplasm', 'malignant tumor of the large intestine', 'malignant neoplasm of large bowel', 'colorectal cancer somatic', 'malignant tumour of the large bowel', 'malignant large intestine tumor', 'malignant large bowel neoplasm', 'malignant large bowel tumor', 'malignant tumor of large intestine', 'cancer of colorectum', 'malignant large bowel tumour', 'colorectal cancer with chromosomal instability somatic', 'malignant neoplasm of the large intestine', 'colon cancer somatic', 'colorectal cancer susceptibility to autosomal dominant somatic mutation', 'malignant neoplasm of colorectum', 'malignant large intestine tumour', 'malignant tumor of large bowel', 'colorectum cancer', 'malignant colorectum neoplasm', 'colorectal cancer autosomal dominant somatic mutation', 'malignant neoplasm of the large bowel', 'malignant tumor of the large bowel', 'malignant colorectal tumour', 'colon cancer susceptibility to autosomal dominant somatic mutation', 'Digestive System Carcinoma', 'gastrointestinal carcinoma (disease)', 'gastrointestinal system carcinoma', 'carcinoma of digestive system', 'digestive system carcinoma', 'gastrointestinal carcinoma', 'carcinoma of the gastrointestinal system', 'cholangiocarcinoma', 'cholangiocarcinoma malignant', 'CC', 'adult primary cholangiocellular carcinoma', 'Cholangiocellular carcinoma', 'cholangiocarcinoma intrahepatic and extrahepatic bile ducts (adenocarcinoma)', 'CCA', 'cholangiosarcoma', 'adult primary cholangiocarcinoma', 'Cholangiocar.- intra/extrahepatic', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'osteosarcoma', 'bone tissue neoplasm', 'osteogenic sarcoma', 'osteosarcoma malignant', 'OS', 'osteosarcoma (disease)', 'sarcoma of osteoid', 'osteoid sarcoma', 'colon adenocarcinoma', 'colonic adenocarcinoma', 'adenocarcinoma of colon', 'adenocarcinoma - colon', 'adenocarcinoma of the colon', 'COAD', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'Malignant Bone Neoplasm', 'osseous tumor', 'bone neoplasm', 'bone tumor', 'osseous tumour', 'bone tumour', 'malignant neoplasm of skeletal element', 'malignant bone neoplasm', 'skeletal element cancer', 'CA - bone cancer', 'cancer of skeletal element', 'malignant osseous tumour', 'malignant neoplasm of bone', 'malignant osseous neoplasm', 'malignant bone tumour', 'malignant osseous tumor', 'malignant tumor of bone', 'osseous cancer', 'cancer of bone', 'malignant skeletal element neoplasm', 'malignant tumor of the bone', 'malignant tumour of the bone', 'malignant bone tumor', 'malignant tumour of bone', 'bone cancer', 'malignant neoplasm of the bone', 'cancer of the bone', 'gastrointestinal stromal tumor', 'gastrointestinal stromal tumor familial isolated cases', 'gastrointestinal stromal sarcoma', 'gant', 'stromal tumor of gastrointestinal tract', 'gastrointestinal stromal tumor isolated cases', 'stromal tumour of gastrointestinal tract', 'gist', 'gastrointestinal stromal tumour (gist)', 'gastrointestinal stromal neoplasm', 'gastrointestinal stromal tumor (gist)', 'gastrointestinal stromal tumors', 'gastrointestinal stromal tumours', 'fallopian tube cancer', 'tumor of the fallopian tube', 'tumour of the fallopian tube', 'malignant tumour of the fallopian tube', 'malignant tumor of fallopian tubes', 'malignant tubal tumor', 'cancer of fallopian tubes', 'fallopian tube malignant neoplasm', 'tumor fallopian tube malignant', 'malignant tumour of fallopian tube', 'malignant fallopian tube neoplasm', 'fallopian tube malignant tumour', 'malignant tumor of fallopian tube', 'malignant tumor of the fallopian tube', 'malignant neoplasm of uterine tube', 'cancer of fallopian tube', 'malignant neoplasm of the fallopian tube', 'malignant tumour of fallopian tubes', 'neoplasm fallopian tube malignant', 'malignant neoplasm of fallopian tube', 'malignant fallopian tube tumor', 'tubal cancer', 'malignant fallopian tube tumour', 'fallopian tube malignant tumor', 'malignant tubal tumour', 'metastatic colorectal cancer', 'adenoid cystic carcinoma', 'cylindroid adenocarcinoma', 'adenoid cystic cancer', 'adenocystic carcinoma', 'cylindroma', 'cribriform carcinoma', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'Vascular endothelial growth factor receptor 2', 'KDR', 'FLK1', 'VEGFR2', 'CD309', 'VEGFR-2', 'FLK-1', 'VEGFR', 'Fetal liver kinase 1', 'Kinase insert domain receptor', 'Protein-tyrosine kinase receptor flk-1', 'vascular endothelial growth factor receptor 2', 'fetal liver kinase 1', 'fetal liver kinase-1', 'kinase insert domain receptor (a type III receptor tyrosine kinase)', 'protein-tyrosine kinase receptor Flk-1', 'soluble VEGFR2', 'tyrosine kinase growth factor receptor', 'kinase insert domain receptor', 'Proto-oncogene tyrosine-protein kinase receptor Ret', 'Soluble RET kinase fragment', 'Extracellular cell-membrane anchored RET cadherin 120 kDa fragment', 'RET', 'CDHF12', 'CDHR16', 'PTC', 'RET51', 'Cadherin family member 12', 'Proto-oncogene c-Ret', 'cadherin-related family member 16', 'RET receptor tyrosine kinase', 'rearranged during transfection', 'HSCR1', 'MEN2A', 'MEN2B', 'MTC1', 'RET-ELE1', 'proto-oncogene tyrosine-protein kinase receptor Ret', 'cadherin family member 12', 'proto-oncogene c-Ret', 'ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1 Hirschsprung disease)', 'ret proto-oncogene', 'Fibroblast growth factor receptor 2', 'FGFR2', 'BEK', 'KGFR', 'KSAM', 'CD332', 'FGFR-2', 'CEK3', 'TK14', 'TK25', 'ECT1', 'K-SAM', 'K-sam', 'Keratinocyte growth factor receptor', 'Crouzon syndrome', 'Pfeiffer syndrome', 'BBDS', 'BFR-1', 'CFD1', 'JWS', 'fibroblast growth factor receptor 2', 'BEK fibroblast growth factor receptor', 'bacteria-expressed kinase', 'keratinocyte growth factor receptor', 'protein tyrosine kinase receptor like 14', 'Vascular endothelial growth factor receptor 3', 'FLT4', 'VEGFR3', 'VEGFR-3', 'FLT-4', 'PCL', 'Fms-like tyrosine kinase 4', 'Tyrosine-protein kinase receptor FLT4', 'vascular endothelial growth factor receptor 3', 'VEGF receptor-3', 'Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4', 'primary congenital lymphedema', 'CHTD7', 'FLT41', 'LMPH1A', 'LMPHM1', 'fms related tyrosine kinase 4', 'fms-like tyrosine kinase 4', 'tyrosine-protein kinase receptor FLT4', 'fms related receptor tyrosine kinase 4', 'Mitogen-activated protein kinase 11', 'MAPK11', 'PRKM11', 'SAPK2', 'SAPK2B', 'MAP kinase 11', 'MAPK 11', 'MAP kinase p38 beta', 'p38b', 'SAPK2b', 'p38-2', 'p38Beta', 'Mitogen-activated protein kinase p38 beta', 'Stress-activated protein kinase 2b', 'P38B', 'P38BETA2', 'mitogen-activated protein kinase 11', 'mitogen-activated protein kinase p38 beta', 'mitogen-activated protein kinase p38-2', 'stress-activated protein kinase-2', 'stress-activated protein kinase-2b', 'Angiopoietin-1 receptor', 'TEK', 'TIE2', 'VMCM', 'VMCM1', 'CD202b', 'hTIE2', 'TIE-2', 'Endothelial tyrosine kinase', 'Tunica interna endothelial cell kinase', 'Tyrosine kinase with Ig and EGF homology domains-2', 'Tyrosine-protein kinase receptor TEK', 'Tyrosine-protein kinase receptor TIE-2', 'p140 TEK', 'angiopoietin-1 receptor', 'CD202B', 'GLC3E', 'TEK tyrosine kinase endothelial', 'endothelial tyrosine kinase', 'tunica interna endothelial cell kinase', 'tyrosine kinase with Ig and EGF homology domains-2', 'tyrosine-protein kinase receptor TEK', 'tyrosine-protein kinase receptor TIE-2', 'TEK receptor tyrosine kinase', 'Platelet-derived growth factor receptor beta', 'PDGFRB', 'PDGFR', 'PDGFR1', 'CD140b', 'PDGF-R-beta', 'PDGFR-beta', 'PDGFR-1', 'JTK12', 'Beta platelet-derived growth factor receptor', 'Beta-type platelet-derived growth factor receptor', 'CD140 antigen-like family member B', 'Platelet-derived growth factor receptor 1', 'CD140B', 'IBGC4', 'IMF1', 'KOGS', 'PENTT', 'platelet-derived growth factor receptor beta', 'Activated tyrosine kinase PDGFRB', 'NDEL1-PDGFRB', 'beta-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 1', 'platelet-derived growth factor receptor beta polypeptide', 'platelet derived growth factor receptor beta', 'Ephrin type-A receptor 2', 'EPHA2', 'ECK', 'Epithelial cell kinase', 'Tyrosine-protein kinase receptor ECK', 'ARCC2', 'CTPA', 'CTPP1', 'CTRCT6', 'ephrin type-A receptor 2', 'epithelial cell receptor protein tyrosine kinase', 'tyrosine-protein kinase receptor ECK', 'EPH receptor A2', 'Mast/stem cell growth factor receptor Kit', 'KIT', 'SCFR', 'CD117', 'PBT', 'C-Kit', 'Piebald trait protein', 'Proto-oncogene c-Kit', 'Tyrosine-protein kinase Kit', 'p145 c-kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog', 'mast/stem cell growth factor receptor Kit', 'MASTC', 'c-Kit protooncogene', 'piebald trait protein', 'proto-oncogene c-Kit', 'proto-oncogene tyrosine-protein kinase Kit', 'tyrosine-protein kinase Kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein', 'KIT proto-oncogene receptor tyrosine kinase', 'Platelet-derived growth factor receptor alpha', 'PDGFRA', 'PDGFR2', 'RHEPDGFRA', 'CD140a', 'PDGF-R-alpha', 'PDGFR-alpha', 'PDGFR-2', 'GAS9', 'Alpha platelet-derived growth factor receptor', 'Alpha-type platelet-derived growth factor receptor', 'CD140 antigen-like family member A', 'CD140a antigen', 'Platelet-derived growth factor alpha receptor', 'Platelet-derived growth factor receptor 2', 'CD140A', 'platelet-derived growth factor receptor alpha', 'alpha-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 2', 'platelet-derived growth factor receptor alpha polypeptide', 'platelet derived growth factor receptor alpha', 'Tyrosine-protein kinase ABL1', 'ABL1', 'ABL', 'JTK7', 'c-ABL', 'p150', 'Abelson murine leukemia viral oncogene homolog 1', 'Abelson tyrosine-protein kinase 1', 'Proto-oncogene c-Abl', 'BCR-ABL', 'CHDSKM', 'bcr/abl', 'c-ABL1', 'v-abl', 'tyrosine-protein kinase ABL1', 'ABL protooncogene 1 nonreceptor tyrosine kinase', 'BCR-ABL1 p190', 'BCR/ABL e8a2 fusion', 'BCR/ABL1 e1a2 fusion protein', 'bcr/c-abl oncogene protein', 'c-abl oncogene 1 receptor tyrosine kinase', 'proto-oncogene c-Abl', 'proto-oncogene tyrosine-protein kinase ABL1', 'v-abl Abelson murine leukemia viral oncogene homolog 1', 'ABL proto-oncogene 1 non-receptor tyrosine kinase', 'Vascular endothelial growth factor receptor 1', 'FLT1', 'FLT', 'FRT', 'VEGFR1', 'VEGFR-1', 'FLT-1', 'Fms-like tyrosine kinase 1', 'Tyrosine-protein kinase FRT', 'Tyrosine-protein kinase receptor FLT', 'Vascular permeability factor receptor', 'vascular endothelial growth factor receptor 1', 'vascular permeability factor receptor', 'fms related tyrosine kinase 1', 'fms-like tyrosine kinase 1', 'fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)', 'tyrosine-protein kinase FRT', 'tyrosine-protein kinase receptor FLT', 'fms related receptor tyrosine kinase 1', 'Fibroblast growth factor receptor 1', 'FGFR1', 'BFGFR', 'CEK', 'FGFBR', 'FLG', 'FLT2', 'HBGFR', 'CD331', 'FGFR-1', 'bFGF-R-1', 'FLT-2', 'H2', 'H3', 'H4', 'H5', 'N-SAM', 'Basic fibroblast growth factor receptor 1', 'Fms-like tyrosine kinase 2', 'N-sam', 'Proto-oncogene c-Fgr', 'ECCL', 'HH2', 'HRTFDS', 'KAL2', 'OGD', 'fibroblast growth factor receptor 1', 'FGFR1/PLAG1 fusion', 'FMS-like tyrosine kinase 2', 'basic fibroblast growth factor receptor 1', 'fms-related tyrosine kinase 2', 'heparin-binding growth factor receptor', 'hydroxyaryl-protein kinase', 'proto-oncogene c-Fgr', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'Tyrosine-protein kinase FRK', 'FRK', 'PTK5', 'RAK', 'GTK', 'FYN-related kinase', 'Nuclear tyrosine protein kinase RAK', 'Protein-tyrosine kinase 5', 'tyrosine-protein kinase FRK', 'PTK5 protein tyrosine kinase 5', 'fyn-related kinase', 'nuclear tyrosine protein kinase RAK', 'protein-tyrosine kinase 5', 'fyn related Src family tyrosine kinase', 'Discoidin domain-containing receptor 2', 'DDR2', 'NTRKR3', 'TKT', 'TYRO10', 'CD167b', 'Discoidin domain receptor 2', 'CD167 antigen-like family member B', 'Discoidin domain-containing receptor tyrosine kinase 2', 'Neurotrophic tyrosine kinase receptor-related 3', 'Receptor protein-tyrosine kinase TKT', 'Tyrosine-protein kinase TYRO10', 'MIG20a', 'WRCN', 'discoidin domain-containing receptor 2', 'cell migration-inducing protein 20', 'discoidin domain receptor 2', 'discoidin domain receptor family member 2', 'discoidin domain-containing receptor tyrosine kinase 2', 'migration-inducing gene 16 protein', 'neurotrophic tyrosine kinase receptor related 3', 'receptor protein-tyrosine kinase TKT', 'tyrosine-protein kinase TYRO10', 'discoidin domain receptor tyrosine kinase 2', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'High affinity nerve growth factor receptor', 'NTRK1', 'MTC', 'TRK', 'TRKA', 'Trk-A', 'Neurotrophic tyrosine kinase receptor type 1', 'TRK1-transforming tyrosine kinase protein', 'Tropomyosin-related kinase A', 'Tyrosine kinase receptor', 'Tyrosine kinase receptor A', 'gp140trk', 'p140-TrkA', 'high affinity nerve growth factor receptor', 'tropomyosin receptor kinase A', 'TRK1', 'Oncogene TRK', 'neurotrophic tyrosine kinase receptor type 1', 'tropomyosin-related kinase A', 'tyrosine kinase receptor A', 'neurotrophic receptor tyrosine kinase 1', 'carcinoma', 'endocrine system disease', 'cancer or benign tumor', 'gastrointestinal disease', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'pancreas disease', 'reproductive system or breast disease', 'cardiovascular disease', 'nervous system disease', 'urinary system disease', 'integumentary system disease', 'musculoskeletal or connective tissue disease', 'disorder of visual system', 'hematologic disease', 'immune system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2012 and has 6 approved and 30 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0000616', 'EFO_0000365', 'MONDO_0004992', 'EFO_0004142', 'MONDO_0005575', 'EFO_1001951']",pharmgkb,toxicity,increased risk of drug toxicity,,rs4864950,TRUE
CHEMBL24828,EPHA2,"ZBTB17, C1orf64, CLCNKA, SPEN","LVEDV, LVEDV_BSA, LVEF, LVESV, LVEDV_BSA, LVEDV, LVESV_BSA, RVEDV_BSA, RVEF, RVESV_BSA, RVESV",cardiotoxicity,United States,VANDETANIB,No,INHIBITOR,Ephrin receptor inhibitor,"['prostate carcinoma', 'carcinoma of prostate', 'prostate gland carcinoma', 'carcinoma of the prostate', 'carcinoma of prostate gland', 'prostate cancer', 'cancer of prostate', 'cancer of the prostate', 'prostate cancer NOS', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'thyroid neoplasm', 'tumor of the thyroid gland', 'tumour of the thyroid', 'neoplasm of thyroid gland', 'Thyroid Gland Neoplasm', 'NEOPL THYROID', 'neoplasm of the thyroid gland', 'tumour of thyroid', 'tumor of thyroid gland', 'thyroid gland tumour', 'tumor of thyroid', 'thyroid neoplasms', 'thyroid gland neoplasm', 'thyroid tumor', 'tumor of the thyroid', 'neoplasm of thyroid', 'THYROID NEOPL', 'thyroid gland tumor', 'Neoplasms Thyroid', 'neoplasm of the thyroid', 'tumour of the thyroid gland', 'Adenoma Thyroid', 'tumour of thyroid gland', 'Neoplasm Thyroid', 'Thyroid Neoplasms', 'thyroid gland neoplasm (disease)', 'THYROID', 'follicular thyroid carcinoma', 'follicular cancer of the thyroid gland', 'thyroid gland follicular cancer', 'follicular cancer of the thyroid', 'well-differentiated follicular carcinoma', 'follicular cancer of thyroid', 'follicular cancer of thyroid gland', 'thyroid gland follicular carcinoma', 'thyroid gland adenocarcinoma', 'follicular carcinoma of the thyroid gland', 'follicular carcinoma', 'thyroid follicular carcinoma', 'well-differentiated follicular adenocarcinoma', 'follicular thyroid gland carcinoma', 'follicular adenocarcinoma well differentiated (morphologic abnormality)', 'carcinoma follicular cell malignant', 'carcinoma of thyroid follicle', 'follicular adenocarcinoma (morphologic abnormality)', 'follicular adenocarcinoma', 'follicular carcinoma of thyroid gland', 'thyroid follicle carcinoma', 'follicular carcinoma of the thyroid', 'follicular thyroid cancer', 'follicular adenocarcinoma well differentiated', 'follicular carcinoma of thyroid', 'head and neck malignant neoplasia', 'head/neck neoplasm', 'tumour of head and neck', 'head and neck neoplasm', 'head and neck tumors', 'head and neck tumours', 'malignant tumor of the head and neck', 'malignant head and neck tumor', 'head and neck cancer', 'cancer of the head and neck', 'malignant neoplasm of the head and neck', 'malignant tumor of head and neck', 'malignant neoplasm of head and neck', 'malignant head and neck tumour', 'malignant craniocervical region neoplasm', 'cancer of craniocervical region', 'malignant neoplasm of craniocervical region', 'malignant tumour of head and neck', 'craniocervical region cancer', 'malignant tumour of the head and neck', 'malignant head and neck neoplasm', 'cancer of head and neck', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'diffuse intrinsic pontine glioma', 'DIPG', 'diffuse midline glioma', 'infiltrative brainstem glioma', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'gastroesophageal junction adenocarcinoma', 'adenocarcinoma of the esophagogastric junction', 'adenocarcinoma of cardioesophageal junction', 'adenocarcinoma of the EG junction', 'adenocarcinoma - GEJ', 'adenocarcinoma of gastroesophageal junction', 'adenocarcinoma of the gastroesophageal junction', 'adenocarcinoma of the GE junction', 'esophagogastric junction adenocarcinoma', 'adenocarcinoma of the cardioesophageal junction', 'esophagogastric adenocarcinoma', 'gastrointestinal stromal tumor', 'gastrointestinal stromal tumor familial isolated cases', 'gastrointestinal stromal sarcoma', 'gant', 'stromal tumor of gastrointestinal tract', 'gastrointestinal stromal tumor isolated cases', 'stromal tumour of gastrointestinal tract', 'gist', 'gastrointestinal stromal tumour (gist)', 'gastrointestinal stromal neoplasm', 'gastrointestinal stromal tumor (gist)', 'gastrointestinal stromal tumors', 'gastrointestinal stromal tumours', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'lung neoplasm', 'verrucous carcinoma', 'warty carcinoma', 'verrucous carcinoma NOS (morphologic abnormality)', 'verrucous squamous carcinoma', 'verrucous squamous cell carcinoma', 'verrucous epidermoid cell carcinoma', 'verrucous epidermoid carcinoma', 'fallopian tube cancer', 'tumor of the fallopian tube', 'tumour of the fallopian tube', 'malignant tumour of the fallopian tube', 'malignant tumor of fallopian tubes', 'malignant tubal tumor', 'cancer of fallopian tubes', 'fallopian tube malignant neoplasm', 'tumor fallopian tube malignant', 'malignant tumour of fallopian tube', 'malignant fallopian tube neoplasm', 'fallopian tube malignant tumour', 'malignant tumor of fallopian tube', 'malignant tumor of the fallopian tube', 'malignant neoplasm of uterine tube', 'cancer of fallopian tube', 'malignant neoplasm of the fallopian tube', 'malignant tumour of fallopian tubes', 'neoplasm fallopian tube malignant', 'malignant neoplasm of fallopian tube', 'malignant fallopian tube tumor', 'tubal cancer', 'malignant fallopian tube tumour', 'fallopian tube malignant tumor', 'malignant tubal tumour', 'Poorly Differentiated Thyroid Gland Carcinoma', 'poorly differentiated thyroid carcinoma', 'insular carcinoma', 'poorly differentiated thyroid gland carcinoma', 'poorly differentiated carcinoma of the thyroid gland', 'poorly differentiated carcinoma of thyroid gland', 'thyroid gland poorly differentiated carcinoma', 'poorly differentiated thyroid gland cancer', 'poorly differentiated thyroid cancer', 'bladder transitional cell carcinoma', 'urinary bladder transitional cell carcinoma', 'bladder urothelial cancer', 'urothelial carcinoma of the urinary bladder', 'transitional cell carcinoma of the urinary bladder', 'bladder urothelial carcinoma', 'transitional cell carcinoma of bladder', 'urothelial bladder carcinoma', 'urinary bladder urothelial carcinoma', 'BLCA', 'head and neck squamous cell carcinoma', 'squamous cell carcinoma of the head and neck', 'squamous cell carcinoma head and neck somatic', 'craniocervical region squamous cell carcinoma', 'squamous cell carcinomas of head and neck', 'SCCHN', 'HNSCC', 'squamous cell carcinoma of head and neck', 'carcinoma of the head and neck', 'squamous cell carcinoma head and neck', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'lung adenocarcinoma', 'adenocarcinoma of the lung', 'non-small cell lung adenocarcinoma', 'bronchogenic lung adenocarcinoma', 'nonsmall cell adenocarcinoma', 'LUAD', 'adenocarcinoma of lung', 'metastatic malignant neoplasm', 'malignant metastatic neoplasm', 'metastatic neoplasm malignant', 'metastatic cancer', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'thyroid cancer', 'thyroid gland cancer', 'malignant tumor of the thyroid gland', 'malignant neoplasm of the thyroid gland', 'malignant thyroid tumor', 'malignant thyroid neoplasm', 'malignant neoplasm of the thyroid', 'malignant tumor of the thyroid', 'malignant tumor of thyroid', 'malignant thyroid gland neoplasm', 'cancer of thyroid gland', 'malignant thyroid gland tumour', 'malignant thyroid tumour', 'malignant tumour of thyroid', 'malignant tumour of the thyroid gland', 'malignant thyroid gland tumor', 'malignant neoplasm of thyroid gland', 'malignant tumour of thyroid gland', 'malignant tumor of thyroid gland', 'malignant tumour of the thyroid', 'malignant neoplasm of thyroid', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'anaplastic oligodendroglioma', 'oligodendroglioma malignant', 'oligodendroglioma anaplastic malignant', 'malignant oligodendroglioma', 'WHO grade III oligodendroglial neoplasm', 'WHO grade III oligodendroglial tumor', 'WHO grade III oligodendroglial tumour', 'undifferentiated oligodendroglioma', 'oligoastrocytoma', 'mixed oligodendroglioma-astrocytoma', 'mixed astrocytoma-oligodendroglioma', 'mixed astrocytic-oligodendroglial tumor', 'mixed astrocytic-oligodendroglial neoplasm', 'mixed astrocytic-oligodendroglial tumour', 'mixed oligo-astrocytoma', 'MOA', 'glioma mixed benign', 'WHO grade II mixed glioma', 'mixed oligoastrocytoma', 'thyroid carcinoma', 'cancer of thyroid', 'cancer of the thyroid', 'head and neck cancer thyroid', 'thyroid gland carcinoma', 'carcinoma of thyroid gland', 'carcinoma of thyroid', 'carcinoma of the thyroid', 'carcinoma of the thyroid gland', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'ureter cancer', 'malignant tumor of the ureter', 'malignant ureteral neoplasm', 'malignant ureter tumour', 'malignant ureteral tumour', 'cancer of ureter', 'malignant tumor of ureter', 'malignant tumour of ureter', 'malignant ureteral tumor', 'malignant tumour of the ureter', 'malignant neoplasm of ureter', 'malignant ureter tumor', 'malignant neoplasm of the ureter', 'malignant ureter neoplasm', 'ureter cancer OF', 'metastasis', 'tumor metastasis', 'tumor cell migration', 'cancer metastasis', 'neoplasm metastasis', 'lip and oral cavity squamous cell carcinoma', 'lip and oral cavity squamous cell cancer', 'lip/oral cavity squam. cell car.', 'squamous cell carcinoma of oral cavity and lip', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'esophageal carcinoma', 'carcinoma of the oesophagus', 'oesophagus carcinoma', 'carcinoma of esophagus', 'esophagus carcinoma', 'carcinoma of the esophagus', 'carcinoma of oesophagus', 'cancer of the oesophagus', 'cancer of esophagus', 'cancer of the esophagus', 'cancer of oesophagus', 'esophageal cancer NOS', 'esophageal cancer', 'stomach neoplasm', 'stomach neoplasm (disease)', 'Neoplasms Stomach', 'tumor of stomach', 'Cancer Stomach', 'Neoplasms Gastric', 'gastric tumour', 'tumour of stomach', 'Gastric Cancers', 'tumor of the stomach', 'GASTRIC NEOPL', 'neoplasm of the stomach', 'gastric tumor', 'Gastric Cancer', 'Stomach Neoplasms', 'gastric neoplasm', 'stomach tumour', 'NEOPL GASTRIC', 'NEOPL STOMACH', 'Cancers Gastric', 'Cancer of the Stomach', 'Gastric Neoplasms', 'Neoplasm Stomach', 'neoplasm of stomach', 'Stomach Cancers', 'stomach tumor', 'Cancer Gastric', 'Cancers Stomach', 'Neoplasm Gastric', 'Gastric Neoplasm', 'STOMACH NEOPL', 'Stomach Cancer', 'Cancer of Stomach', 'tumour of the stomach', 'renal pelvis/ureter urothelial carcinoma', 'renal pelvis and ureter transitional cell carcinoma', 'transitional cell cancer of the renal pelvis and ureter', 'renal pelvis and ureter urothelial carcinoma', 'TCC of the renal pelvis and ureter', 'TCC of renal pelvis and ureter', 'renal pelvis and ureter transitional cell cancer', 'renal pelvis and ureter TCC', 'transitional cell carcinoma of renal pelvis and ureter', 'transitional cell cancer of renal pelvis and ureter', 'urothelial carcinoma of the renal pelvis and ureter', 'anaplastic astrocytoma', 'grade III astrocytoma', 'grade III astrocytic neoplasm', 'astrocytoma anaplastic malignant', 'malignant astrocytoma', 'grade III astrocytic tumor', 'grade III astrocytic tumour', 'mesothelioma', 'Central Nervous System Neoplasm', 'tumour of central nervous system', 'tumour of CNS', 'tumor of central nervous system', 'CNS tumor', 'tumour of the CNS', 'tumour of the central nervous system', 'central nervous system neoplasm', 'neoplasm of central nervous system', 'brain/spinal cord tumour', 'tumor of the central nervous system', 'CNS tumour', 'central nervous system neoplasm (disease)', 'tumor of the CNS', 'CNS neoplasm', 'neoplasm of the central nervous system', 'neoplasm of CNS', 'tumor of CNS', 'central nervous system tumour', 'central nervous system tumor', 'brain/spinal cord tumor', 'gastric cancer', 'malignant tumor of lesser curve of stomach', 'malignant tumour of body of stomach', 'malignant neoplasm of stomach', 'gastric cancer risk after h. pylori infection', 'malignant neoplasm of lesser curve of stomach', 'malignant gastric tumour', 'malignant gastric neoplasm', 'malignant tumour of greater curve of stomach', 'Ca lesser curvature - stomach', 'malignant stomach neoplasm', 'malignant tumor of greater curve of stomach', 'malignant tumor of body of stomach', 'malignant tumour of the stomach', 'malignant tumour of stomach', 'malignant tumor of the stomach', 'gastric cancer somatic', 'malignant tumour of lesser curve of stomach', 'malignant neoplasm of the stomach', 'malignant tumor of stomach', 'cancer of stomach', 'malignant gastric tumor', 'stomach cancer', 'Ca body - stomach', 'ca greater curvature of stomach', 'malignant neoplasm of body of stomach', 'gastric cancer intestinal', 'neuroblastoma', '[M]Neuroblastoma NOS (morphologic abnormality)', 'neuroblastoma (Schwannian Stroma-poor)', '[M]Neuroblastoma NOS', 'neural Crest tumor malignant', 'NB - Neuroblastoma', 'neuroblastoma malignant', 'Central neuroblastoma', 'Neuroblastoma NOS', 'Sympathicoblastoma', 'neuroblastoma (Schwannian Stroma-Poor)', 'Neuroblastomas', 'neuroblastoma (morphologic abnormality)', '(neuroblastoma NOS) or (sympathicoblastoma)', 'neuroblastoma NOS (morphologic abnormality)', 'NB', 'gliosarcoma', 'glioblastoma with a sarcomatous component', 'glioblastoma with sarcomatous component', 'sarcomatous glioblastoma', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'peritoneum cancer', 'peritoneal cancer', 'peritoneal cavity cancer', 'malignant peritoneal neoplasm', 'cancer of peritoneum', 'malignant peritoneum neoplasm', 'cancer of the peritoneum', 'malignant neoplasm of peritoneum', 'peritoneal neoplasm', 'urinary bladder cancer', 'tumor of the bladder', 'tumour of the bladder', 'malignant neoplasm of the urinary bladder', 'malignant neoplasm bladder', 'malignant urinary bladder tumor', 'malignant tumor of the bladder', 'malignant tumor of bladder', 'urinary bladder malignant tumour', 'malignant tumor of the urinary bladder', 'urinary bladder malignant neoplasm', 'malignant neoplasm of the bladder', 'malignant bladder neoplasm', 'malignant bladder tumour', 'malignant tumour of the urinary bladder', 'malignant urinary bladder tumour', 'malignant urinary bladder neoplasm', 'malignant neoplasm urinary bladder', 'malignant bladder tumor', 'bladder cancer somatic', 'malignant tumor urinary bladder', 'malignant tumour of bladder', 'malignant tumor of urinary bladder', 'malignant tumour of the bladder', 'malignant tumour of urinary bladder', 'cancer of urinary bladder', 'malignant neoplasm of bladder', 'malignant neoplasm of urinary bladder', 'urinary bladder malignant tumor', 'malignant glioma', 'glioma', 'neuroglial tumour', 'neuroglial tumor', 'malignant neuroglial neoplasm', 'glial cell tumour', 'glioma malignant', 'malignant glial tumor', 'high-grade glioma', 'glial cell tumor', 'malignant glial neoplasm', 'malignant neuroglial tumour', 'malignant glial tumour', 'high grade glioma', 'malignant neuroglial tumor', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'clear cell renal carcinoma', 'kidney clear cell adenocarcinoma', 'RCC clear cell adenocarcinoma', 'conventional (clear cell) renal cell adenocarcinoma', 'renal clear cell carcinoma', 'clear cell adenocarcinoma of the kidney', 'hypernephroma', 'conventional (clear cell) renal cell carcinoma', 'clear cell adenocarcinoma of kidney', 'clear cell renal cell cancer', 'renal cell carcinoma clear cell adenocarcinoma', 'clear cell renal cell carcinoma', 'clear cell adenocarcinoma kidney', 'kidney clear cell carcinoma', 'renal clear cell adenocarcinoma', 'conventional renal cell carcinoma', 'clear cell carcinoma of the kidney', 'Grawitz tumour', 'clear cell carcinoma of kidney', 'Grawitz tumor', 'clear cell kidney carcinoma', 'clear-cell metastatic renal cell carcinoma', 'breast cancer', 'mammary tumour', 'mammary tumor', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'urethra cancer', 'malignant urethral neoplasm', 'malignant urethra tumour', 'malignant tumour of the urethra', 'urethral Ca', 'malignant tumor of urethra', 'malignant urethra tumor', 'malignant tumor of the urethra', 'malignant urethral tumor', 'malignant neoplasm of the urethra', 'malignant urethra neoplasm', 'malignant neoplasm of urethra', 'malignant tumour of urethra', 'malignant urethral tumour', 'cancer of urethra', 'urethral cancer', 'papillary thyroid carcinoma', 'papillary cancer of the thyroid gland', 'papillary carcinoma of the thyroid', 'thyroid gland papillary carcinoma', 'papillary carcinoma of thyroid', 'papillary carcinoma of the thyroid gland', 'PTC', 'papillary thyroid cancer', 'papillary cancer of the thyroid', 'thyroid gland papillary cancer', 'papillary thyroid gland carcinoma', 'papillary carcinoma of thyroid gland', 'thyroid papillary carcinoma', 'papillary cancer of thyroid gland', 'papillary cancer of thyroid', 'medullary thyroid gland carcinoma', 'medullary carcinoma of thyroid gland', 'C cell carcinoma', 'thyroid gland neuroendocrine carcinoma', 'medullary thyroid cancer', 'medullary carcinoma of thyroid', 'ultimobranchial thyroid tumor', 'parafollicular cell carcinoma', 'carcinoma C-cell malignant', 'ultimobranchial thyroid tumour', 'thyroid gland medullary cancer', 'carcinoma of parafollicular cell', 'thyroid medullary carcinoma', 'medullary carcinoma of the thyroid', 'thyroid gland medullary carcinoma', 'medullary carcinoma of the thyroid gland', 'MTC', 'medullary thyroid carcinoma', 'medullary carcinoma', 'THME', 'thyroid carcinoma medullary', 'thyroid cancer medullary', 'medullary thyroid cancer (MTC)', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'colorectal adenocarcinoma', 'colorectum adenocarcinoma', 'adenocarcinoma of the large bowel', 'colorectal (colon or rectal) adenocarcinoma', 'adenocarcinoma of large bowel', 'large intestine adenocarcinoma', 'adenocarcinoma of the large intestine', 'large bowel adenocarcinoma', 'adenocarcinoma of large intestine', 'low grade glioma', 'low-grade glioma', 'Vascular endothelial growth factor receptor 2', 'KDR', 'FLK1', 'VEGFR2', 'CD309', 'VEGFR-2', 'FLK-1', 'VEGFR', 'Fetal liver kinase 1', 'Kinase insert domain receptor', 'Protein-tyrosine kinase receptor flk-1', 'vascular endothelial growth factor receptor 2', 'fetal liver kinase 1', 'fetal liver kinase-1', 'kinase insert domain receptor (a type III receptor tyrosine kinase)', 'protein-tyrosine kinase receptor Flk-1', 'soluble VEGFR2', 'tyrosine kinase growth factor receptor', 'kinase insert domain receptor', 'Proto-oncogene tyrosine-protein kinase receptor Ret', 'Soluble RET kinase fragment', 'Extracellular cell-membrane anchored RET cadherin 120 kDa fragment', 'RET', 'CDHF12', 'CDHR16', 'RET51', 'Cadherin family member 12', 'Proto-oncogene c-Ret', 'cadherin-related family member 16', 'RET receptor tyrosine kinase', 'rearranged during transfection', 'HSCR1', 'MEN2A', 'MEN2B', 'MTC1', 'RET-ELE1', 'proto-oncogene tyrosine-protein kinase receptor Ret', 'cadherin family member 12', 'proto-oncogene c-Ret', 'ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1 Hirschsprung disease)', 'ret proto-oncogene', 'Ephrin type-B receptor 6', 'EPHB6', 'HEP', 'Tyrosine-protein kinase-defective receptor EPH-6', 'ephrin type-B receptor 6', 'human kinase-defective Eph-family receptor protein', 'tyrosine-protein kinase-defective receptor EPH-6', 'EPH receptor B6', 'Receptor tyrosine-protein kinase erbB-3', 'ERBB3', 'HER3', 'Proto-oncogene-like protein c-ErbB-3', 'Tyrosine kinase-type cell surface receptor HER3', 'human epidermal growth factor receptor 3', 'ErbB-3', 'FERLK', 'LCCS2', 'MDA-BF-1', 'VSCN1', 'c-erbB-3', 'c-erbB3', 'erbB3-S', 'p180-ErbB3', 'p45-sErbB3', 'p85-sErbB3', 'receptor tyrosine-protein kinase erbB-3', 'proto-oncogene-like protein c-ErbB-3', 'tyrosine kinase-type cell surface receptor HER3', 'v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3', 'erb-b2 receptor tyrosine kinase 3', 'Vascular endothelial growth factor receptor 3', 'FLT4', 'VEGFR3', 'VEGFR-3', 'FLT-4', 'PCL', 'Fms-like tyrosine kinase 4', 'Tyrosine-protein kinase receptor FLT4', 'vascular endothelial growth factor receptor 3', 'VEGF receptor-3', 'Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4', 'primary congenital lymphedema', 'CHTD7', 'FLT41', 'LMPH1A', 'LMPHM1', 'fms related tyrosine kinase 4', 'fms-like tyrosine kinase 4', 'tyrosine-protein kinase receptor FLT4', 'fms related receptor tyrosine kinase 4', 'Angiopoietin-1 receptor', 'TEK', 'TIE2', 'VMCM', 'VMCM1', 'CD202b', 'hTIE2', 'TIE-2', 'Endothelial tyrosine kinase', 'Tunica interna endothelial cell kinase', 'Tyrosine kinase with Ig and EGF homology domains-2', 'Tyrosine-protein kinase receptor TEK', 'Tyrosine-protein kinase receptor TIE-2', 'p140 TEK', 'angiopoietin-1 receptor', 'CD202B', 'GLC3E', 'TEK tyrosine kinase endothelial', 'endothelial tyrosine kinase', 'tunica interna endothelial cell kinase', 'tyrosine kinase with Ig and EGF homology domains-2', 'tyrosine-protein kinase receptor TEK', 'tyrosine-protein kinase receptor TIE-2', 'TEK receptor tyrosine kinase', 'Ephrin type-A receptor 1', 'EPHA1', 'EPH', 'EPHT', 'EPHT1', 'hEpha1', 'EPH tyrosine kinase', 'EPH tyrosine kinase 1', 'Erythropoietin-producing hepatoma receptor', 'Tyrosine-protein kinase receptor EPH', 'ephrin type-A receptor 1', 'eph tyrosine kinase 1', 'erythropoietin-producing hepatoma amplified sequence', 'erythropoietin-producing hepatoma receptor', 'oncogene EPH', 'tyrosine-protein kinase receptor EPH', 'EPH receptor A1', 'Ephrin type-A receptor 7', 'EPHA7', 'EHK3', 'HEK11', 'EHK-3', 'EK11', 'hEK11', 'Hek11', 'EPH homology kinase 3', 'EPH-like kinase 11', 'ephrin type-A receptor 7', 'Eph homology kinase-3', 'receptor protein-tyrosine kinase HEK11', 'tyrosine-protein kinase receptor EHK-3', 'EPH receptor A7', 'Receptor tyrosine-protein kinase erbB-4', 'ERBB4 intracellular domain', 'ERBB4', 'HER4', '4ICD', 'E4ICD', 'ALS19', 'Proto-oncogene-like protein c-ErbB-4', 'Tyrosine kinase-type cell surface receptor HER4', 'p180erbB4', 's80HER4', 'human epidermal growth factor receptor 4', 'receptor tyrosine-protein kinase erbB-4', 'avian erythroblastic leukemia viral (v-erb-b2) oncogene homolog 4', 'proto-oncogene-like protein c-ErbB-4', 'tyrosine kinase-type cell surface receptor HER4', 'v-erb-a erythroblastic leukemia viral oncogene homolog 4', 'v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4', 'erb-b2 receptor tyrosine kinase 4', 'Ephrin type-A receptor 2', 'EPHA2', 'ECK', 'Epithelial cell kinase', 'Tyrosine-protein kinase receptor ECK', 'ARCC2', 'CTPA', 'CTPP1', 'CTRCT6', 'ephrin type-A receptor 2', 'epithelial cell receptor protein tyrosine kinase', 'tyrosine-protein kinase receptor ECK', 'EPH receptor A2', 'Ephrin type-B receptor 4', 'EPHB4', 'HTK', 'MYK1', 'TYRO11', 'Tyro11', 'Hepatoma transmembrane kinase', 'Tyrosine-protein kinase TYRO11', 'CMAVM2', 'HFASD', 'LMPHM7', 'ephrin type-B receptor 4', 'ephrin receptor EphB4', 'hepatoma transmembrane kinase', 'tyrosine-protein kinase TYRO11', 'tyrosine-protein kinase receptor HTK', 'EPH receptor B4', 'Ephrin type-A receptor 3', 'EPHA3', 'ETK', 'ETK1', 'HEK', 'TYRO4', 'EK4', 'hEK4', 'Human embryo kinase', 'Eph-like tyrosine kinase 1', 'HEK4', 'EPH-like kinase 4', 'Tyrosine-protein kinase TYRO4', 'Tyrosine-protein kinase receptor ETK1', 'ephrin type-A receptor 3', 'TYRO4 protein tyrosine kinase', 'eph-like tyrosine kinase 1', 'human embryo kinase 1', 'testicular tissue protein Li 64', 'tyrosine-protein kinase receptor ETK1', 'EPH receptor A3', 'Ephrin type-A receptor 4', 'EPHA4', 'HEK8', 'SEK', 'TYRO1', 'EK8', 'hEK8', 'Hek8', 'EPH-like kinase 8', 'Tyrosine-protein kinase TYRO1', 'Tyrosine-protein kinase receptor SEK', 'ephrin type-A receptor 4', 'TYRO1 protein tyrosine kinase', 'receptor protein-tyrosine kinase HEK8', 'tyrosine-protein kinase TYRO1', 'tyrosine-protein kinase receptor SEK', 'EPH receptor A4', 'Protein-tyrosine kinase 6', 'PTK6', 'BRK', 'Breast tumor kinase', 'Tyrosine-protein kinase BRK', 'protein-tyrosine kinase 6', 'PTK6 protein tyrosine kinase 6', 'breast tumor kinase', 'protein-tyrosine kinase BRK', 'tyrosine-protein kinase BRK', 'protein tyrosine kinase 6', 'Epidermal growth factor receptor', 'EGFR', 'ERBB', 'ERBB1', 'HER1', 'ERRP', 'Proto-oncogene c-ErbB-1', 'Receptor tyrosine-protein kinase erbB-1', 'erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)', 'erb-b2 receptor tyrosine kinase 1', 'NISBD2', 'PIG61', 'mENA', 'epidermal growth factor receptor', 'EGFR vIII', 'avian erythroblastic leukemia viral (v-erb-b) oncogene homolog', 'cell growth inhibiting protein 40', 'cell proliferation-inducing protein 61', 'epidermal growth factor receptor tyrosine kin","","","","","","",,"",
CHEMBL123292,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",CYCLOHEXIMIDE,No,INHIBITOR,80S Ribosome inhibitor,[],protein nucleic-acid complex,Small molecule drug.,"","","","",,"",
CHEMBL2109124,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",DORLIMOMAB ARITOX,No,INHIBITOR,80S Ribosome inhibitor,[],protein nucleic-acid complex,Antibody drug with a maximum clinical trial phase of I.,"","","","",,"",
CHEMBL256997,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,not have improvement in chloride transport,,rs77010898,FALSE
CHEMBL256997,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,improvement in chloride transport,,rs75039782,FALSE
CHEMBL256997,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,improvement in chloride transport,,rs113993959,FALSE
CHEMBL256997,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,not have improvement in chloride transport,,rs75039782,FALSE
CHEMBL256997,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,not have improvement in chloride transport,,rs113993959,FALSE
CHEMBL256997,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,improvement in chloride transport,,rs77010898,FALSE
CHEMBL4297744,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",ELX-02,No,MODULATOR,80S Ribosome modulator,"['cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Alport syndrome', 'hereditary nephritis', 'Alport deafness-nephropathy', """"""""Alport's syndrome"""""""", 'kidney disease', 'renal system disease', 'Kidney Disorder', 'disease or disorder of kidney', 'renal disorder', 'disorder of kidney', 'renal disease', 'disease of kidney', 'nephropathy', 'kidney diseases', 'kidney disorder', 'kidney disease or disorder', 'cystinosis', 'cystine storage disease', 'Protein defect of cystin transport', 'cystine diathesis', 'Cystinoses', 'cystine disease', 'genetic disorder', 'genetic disease', 'genetic condition', 'inherited disease', 'hereditary diseases', 'inherited genetic disease', 'hereditary disease or disorder', 'hereditary disease', 'molecular disease', 'Mendelian disease', 'inborn disorder', 'familial disorder', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'urinary system disease', 'nutritional or metabolic disease']",protein nucleic-acid complex,Unknown drug with a maximum clinical trial phase of II (across all indications) and has 5 investigational indications.,[],"","","",,"",
CHEMBL4297789,RPL7A,ABO,"LVEDV, LVSV_BSA, LVSV, LVEDV_BSA","","",MT-3724,No,INHIBITOR,80S Ribosome inhibitor,"['non-Hodgkins lymphoma', """"""""non-Hodgkin's lymphoma"""""""", 'NHL', 'non-Hodgkin lymphoma', """"""""non-Hodgkin's lymphoma (NHL)"""""""", 'lymphoid leukemia', 'lymphocytic leukaemia', 'lymphogenous leukaemia', 'lymphoid leukemia (disease)', 'lymphogenous leukemia', 'leukemia LYMPHOCYTIC malignant', 'lymphoid leukaemia (disease)', 'subacute lymphoid leukemia', 'lymphocytic leukemia', 'subacute lymphoid leukaemia', 'diffuse large B-cell lymphoma', 'DLBCL', 'chronic lymphocytic leukemia', 'B-cell lymphocytic leukaemia', 'CLL', 'B-CLL', 'BCLL', 'chronic lymphogenous leukaemia', 'B cell lymphocytic leukemia', 'chronic lymphatic leukaemia', 'B cell CLL', 'B-cell lymphocytic leukemia', 'small lymphocytic lymphoma', 'B-cell chronic lymphoid leukaemia', 'lymphoplasmacytic leukaemia', 'B-cell chronic lymphocytic leukemia', 'B-cell chronic lymphogenous leukemia', 'B-cell chronic lymphogenous leukaemia', 'B-cell chronic lymphoid leukemia', 'B cell chronic lymphocytic leukaemia', 'chronic B-cell lymphocytic leukaemia', 'B cell lymphocytic leukaemia', 'chronic lymphocytic leukemia (CLL)', 'B-cell CLL', 'chronic lymphocytic leukaemia (CLL)', 'chronic lymphatic leukemia', 'chronic B-cell lymphocytic leukemia', 'B cell chronic lymphocytic leukemia', 'lymphoplasmacytic leukemia', 'hematopoeitic - chronic lymphocytic leukemia (CLL)', 'hematopoeitic - chronic lymphocytic leukaemia (CLL)', 'chronic lymphogenous leukemia', 'chronic lymphocytic leukaemia', 'leukemia chronic LYMPHOCYTIC', 'leukemia chronic lymphatic', 'leukemia lymphocytic chronic', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'B-lymphocyte antigen CD20', 'MS4A1', 'CD20', 'B1', 'Bp35', 'FMC7', 'B-lymphocyte surface antigen B1', 'Leukocyte surface antigen Leu-16', 'Membrane-spanning 4-domains subfamily A member 1', 'CVID5', 'LEU-16', 'B-lymphocyte cell-surface antigen B1', 'CD20 antigen', 'CD20 receptor', 'leukocyte surface antigen Leu-16', 'membrane-spanning 4-domains subfamily A member 1', 'membrane spanning 4-domains A1', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'hematologic disease', 'genetic familial or congenital disease', 'cancer or benign tumor', 'immune system disease']",protein nucleic-acid complex,Unknown drug with a maximum clinical trial phase of II (across all indications) and has 4 investigational indications.,[],"","","",,"",
CHEMBL3039529,TNNT3,LSP1,"LVEDV_BSA, LVM, LVM_BSA, LVEDV, LVESV, LVSV_BSA, LVEDV, LVESV, LVEDV_BSA, LVESV_BSA, LVSV, RVSV","","",TIRASEMTIV,No,ACTIVATOR,Fast skeletal troponin complex activator,"['peripheral arterial disease', 'Occlusive Peripheral Arterial Disease', 'peripheral arterial disorder', 'peripheral artery disease', 'pad', 'peripheral arterial diseases', 'amyotrophic lateral sclerosis', 'Lou Gehrig disease', 'motor neuron disease bulbar', 'ALS', """"""""Lou Gehrig's disease"""""""", 'Charcot disease', 'Myasthenia gravis', 'myasthenia gravis', 'autoimmune myasthenia gravis', 'acquired myasthenia', 'MG', 'intermittent vascular claudication', 'Claudication Intermittent', """"""""Charcot's syndrome"""""""", 'intermittent claudication', 'Intermittent Claudication', 'Troponin T fast skeletal muscle', 'TNNT3', 'TnTf', 'fTnT', 'AMCD2B', 'DA2B', 'FSSV', 'DKFZp779M2348', 'Beta-TnTF', 'Fast skeletal muscle troponin T', 'troponin-T3 skeletal fast', 'DA2B2', 'TNTF', 'beta-TnTF', 'troponin T fast skeletal muscle', 'troponin T type 3 (skeletal fast)', 'troponin T3 fast skeletal type', 'Troponin C skeletal muscle', 'TNNC2', 'FAP85', 'CFAP85', 'CMYP15', 'MYONRI', 'troponin C skeletal muscle', 'troponin C type 2 (fast)', 'troponin C2 fast skeletal type', 'Troponin I fast skeletal muscle', 'TNNI2', 'fsTnI', 'Troponin I fast-twitch isoform', 'troponin I fast-twitch skeletal muscle isoform', 'troponin I fast twitch 2', 'DA2B1', 'troponin I fast skeletal muscle', 'troponin I type 2 (skeletal fast)', 'troponin I skeletal fast', 'troponin I2 fast skeletal type', 'cardiovascular disease', 'nervous system disease', 'immune system disease']",protein complex,Small molecule drug with a maximum clinical trial phase of III (across all indications) and has 4 investigational indications.,[],"","","",,"",
CHEMBL4297600,TNNT3,LSP1,"LVEDV_BSA, LVM, LVM_BSA, LVEDV, LVESV, LVSV_BSA, LVEDV, LVESV, LVEDV_BSA, LVESV_BSA, LVSV, RVSV","","",RELDESEMTIV,No,ACTIVATOR,Fast skeletal troponin complex activator,"['chronic obstructive pulmonary disease', 'DISEASE (COPD) CHRONIC OBSTRUCTIVE', 'COLD (chronic obstructive lung disease)', 'Chronic irreversible airway obstruction', 'chronic obstructive pulmonary disease and allied conditions', 'CHRONIC OBSTRUCTIVE LUNG DIS', 'chronic obstructive lung disease (disorder)', 'chronic obstructive pulmonary disease (COPD)', 'COPD NOS', 'chronic obstructive airways disease', 'CHRONIC OBSTRUCTIVE AIRWAY DIS', 'CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD)', 'Chronic airway disease', 'Airflow Obstructions Chronic', 'COLD', 'chronic obstructive lung disease [Ambiguous]', 'PULMONARY DISEASE (COPD) CHRONIC OBSTRUCTIVE', 'Chronic Obstructive Airways Disease', 'Chronic obstructive pulmonary disease finding', 'Chronic Obstructive Pulmonary Disease (COPD)', 'OBSTRUCTIVE PULMONARY DISEASE (COPD) CHRONIC', 'Dops', 'Pulmonary Disease Chronic Obstructive', 'cold (chronic obstructive lung disease)', 'disease (COPD) chronic obstructive', 'Chronic airway obstruction', 'obstructive lung disease chronic', 'Chronic obstructive pulmonary disease finding (finding)', 'Chronic obstructive lung disease NOS', 'cold', 'pulmonary disease (COPD) chronic obstructive', 'Chronic obstructive pulmonary disease NOS', 'Chronic obstructive lung disease NEC', 'PULM DIS CHRONIC OBSTRUCTIVE', 'Chronic airflow limitation', 'COLD - Chronic obstructive lung disease', 'chronic airway obstruction NEC in ICD9CM_2006', 'COAD - Chronic obstructive airways disease', 'CAFL - Chronic airflow limitation', 'COAD', 'COPD chronic obstructive pulmonary disease', 'chronic obstructive airways disease NOS (disorder)', 'Chronic Airflow Obstruction', 'CAO - Chronic airflow obstruction', 'Airflow Obstruction Chronic', 'chronic obstructive lung disease', 'Chronic Airflow Obstructions', 'obstructive pulmonary disease (COPD) chronic', 'chronic obstructive airways disease NOS', 'chronic airway obstruction not elsewhere classified', 'COPD - Chronic obstructive pulmonary disease', 'CHRONIC OBSTRUCTIVE PULM DIS', 'Chronic Obstructive Lung Disease', 'COPD', 'chronic obstructive airway disease', 'CAL - Chronic airflow limitation', 'COPD CHRONIC OBSTRUCTIVE PULMONARY DISEASE', 'spinal muscular atrophy', 'amyotrophic lateral sclerosis', 'Lou Gehrig disease', 'motor neuron disease bulbar', 'ALS', """"""""Lou Gehrig's disease"""""""", 'Charcot disease', 'Troponin T fast skeletal muscle', 'TNNT3', 'TnTf', 'fTnT', 'AMCD2B', 'DA2B', 'FSSV', 'DKFZp779M2348', 'Beta-TnTF', 'Fast skeletal muscle troponin T', 'troponin-T3 skeletal fast', 'DA2B2', 'TNTF', 'beta-TnTF', 'troponin T fast skeletal muscle', 'troponin T type 3 (skeletal fast)', 'troponin T3 fast skeletal type', 'Troponin C skeletal muscle', 'TNNC2', 'FAP85', 'CFAP85', 'CMYP15', 'MYONRI', 'troponin C skeletal muscle', 'troponin C type 2 (fast)', 'troponin C2 fast skeletal type', 'Troponin I fast skeletal muscle', 'TNNI2', 'fsTnI', 'Troponin I fast-twitch isoform', 'troponin I fast-twitch skeletal muscle isoform', 'troponin I fast twitch 2', 'DA2B1', 'troponin I fast skeletal muscle', 'troponin I type 2 (skeletal fast)', 'troponin I skeletal fast', 'troponin I2 fast skeletal type', 'respiratory or thoracic disease', 'nervous system disease']",protein complex,Small molecule drug with a maximum clinical trial phase of III (across all indications) and has 3 investigational indications.,[],"","","",,"",
CHEMBL123292,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",CYCLOHEXIMIDE,No,INHIBITOR,80S Ribosome inhibitor,[],protein nucleic-acid complex,Small molecule drug.,"","","","",,"",
CHEMBL1800955,MYL2,"BRAP, ATXN2, MAPKAPK5-AS1","LVEDV, LVEDV_BSA, LVESV_BSA, LVESV, LVSV_BSA, LVMVR, LVEDV_BSA, LVMVR, LVESV, LVEDV, LVSV, LVSV_BSA, LVESV_BSA, RVEF, RVESV_BSA, RVEDV, RVESV, RVSV, RVEDV_BSA, RVSV_BSA","","",OMECAMTIV MECARBIL,Yes,ACTIVATOR,Cardiac myosin activator,"['heart failure', 'Weak heart', 'Heart failure NOS', 'Heart failure unspecified', 'Heart: [weak] or [failure NOS]', 'Heart failure NOS (disorder)', 'cardiac failure', 'cardiac dysfunction', 'failure heart', 'Heart failure (disorder)', 'insufficiency Cardiac', 'cardiac insufficiency', 'Reduced left ventricular ejection fraction', 'Reduced ejection fraction', 'Myosin-6', 'MYH6', 'MYHCA', 'MyHC-alpha', 'Myosin heavy chain 6', 'Myosin heavy chain cardiac muscle alpha isoform', 'cardiomyopathy hypertrophic 1', 'ASD3', 'CMD1EE', 'CMH14', 'MYHC', 'SSS3', 'alpha-MHC', 'myosin-6', 'myHC-alpha', 'myosin heavy polypeptide 6 cardiac muscle alpha (cardiomyopathy hypertrophic 1)', 'myosin heavy chain 6', 'Myosin light chain 3', 'MYL3', 'CMLC1', 'MLC1SB', 'VLCl', 'MLC-lV/sb', 'CMH8', 'VLC1', 'MLC1V', 'Cardiac myosin light chain 1', 'Myosin light chain 1 slow-twitch muscle B/ventricular isoform', 'Ventricular myosin alkali light chain', 'Ventricular myosin light chain 1', 'Ventricular/slow twitch myosin alkali light chain', 'myosin light chain 3', 'cardiac myosin light chain 1', 'myosin light chain 3 alkali; ventricular skeletal slow', 'myosin light polypeptide 3 alkali; ventricular skeletal slow', 'ventricular myosin alkali light chain', 'ventricular myosin light chain 1', 'ventricular/slow twitch myosin alkali light chain', 'Myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'MYL2', 'MLC2', 'MLC-2', 'MLC-2v', 'MLC-2s/v', 'CMH10', 'Cardiac myosin light chain 2', 'Myosin light chain 2 slow skeletal/ventricular muscle isoform', 'Ventricular myosin light chain 2', 'cardiac ventricular myosin light chain 2', 'MFM12', 'myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'RLC of myosin', 'S15D myosin regulatory light chain 2', 'T160D myosin regulatory light chain 2', 'cardiac myosin light chain 2', 'myosin light chain 2 regulatory cardiac slow', 'myosin light polypeptide 2 regulatory cardiac slow', 'regulatory light chain of myosin', 'slow cardiac myosin regulatory light chain 2', 'ventricular myosin light chain 2', 'myosin light chain 2', 'Myosin regulatory light chain 2 atrial isoform', 'MYL7', 'MYL2A', 'MYLC2A', 'MLC-2a', 'MLC2a', 'Myosin light chain 2a', 'Myosin regulatory light chain 7', 'myosin regulatory light chain 2 atrial isoform', 'myosin light chain 2a', 'myosin regulatory light chain 7', 'myosin light chain 7 regulatory', 'myosin light polypeptide 7 regulatory', 'myosin light chain 7', 'Myosin-7B', 'MYH7B', 'KIAA1512', 'dJ756N5.1', 'MYH14', 'MHC14', 'lncMYH7b', 'Antigen MLAA-21', 'Myosin cardiac muscle beta chain', 'Myosin heavy chain 7B cardiac muscle beta isoform', 'Slow A MYH14', 'myosin-7B', 'U937-associated antigen', 'antigen MLAA-21', 'myosin heavy chain 7B cardiac muscle beta', 'myosin heavy polypeptide 7B cardiac muscle beta', 'slow A MYH14', 'myosin heavy chain 7B', 'Myosin-7', 'MYH7', 'MYHCB', 'MyHC-slow', 'MyHC-beta', 'CMD1S', 'Myosin heavy chain 7', 'Myosin heavy chain slow isoform', 'Myosin heavy chain cardiac muscle beta isoform', 'CMH1', 'CMYP7A', 'CMYP7B', 'MPD1', 'SPMD', 'SPMM', 'myosin-7', 'cardiac muscle myosin heavy chain 7 beta', 'myHC-beta', 'myhc-slow', 'myosin 7', 'myosin heavy chain beta-subunit', 'myosin heavy chain 7 cardiac muscle beta', 'myosin heavy polypeptide 7 cardiac muscle beta', 'rhabdomyosarcoma antigen MU-RMS-40.7A', 'myosin heavy chain 7', 'Myosin light chain 4', 'MYL4', 'MLC1', 'PRO1957', 'ALC1', 'AMLC', 'GT1', 'Myosin light chain 1 embryonic muscle/atrial isoform', 'Myosin light chain alkali GT-1 isoform', 'myosin atrial/fetal muscle light chain', 'atrial myosin light chain 1', 'myosin light chain 4', 'myosin light chain 4 alkali; atrial embryonic', 'myosin light polypeptide 4 alkali; atrial embryonic', 'cardiovascular disease', 'phenotype']",protein complex,Small molecule drug with a maximum clinical trial phase of III and has 1 investigational indication.,[],"","","",,"",
CHEMBL2109124,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",DORLIMOMAB ARITOX,No,INHIBITOR,80S Ribosome inhibitor,[],protein nucleic-acid complex,Antibody drug with a maximum clinical trial phase of I.,"","","","",,"",
CHEMBL256997,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,not have improvement in chloride transport,,rs77010898,FALSE
CHEMBL256997,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,improvement in chloride transport,,rs75039782,FALSE
CHEMBL256997,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,improvement in chloride transport,,rs113993959,FALSE
CHEMBL256997,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,not have improvement in chloride transport,,rs75039782,FALSE
CHEMBL256997,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,not have improvement in chloride transport,,rs113993959,FALSE
CHEMBL256997,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ATALUREN,Yes,MODULATOR,80S Ribosome modulator,"['epilepsy', 'Generalized seizure (finding)', 'Epileptic Seizure', 'Epilepsy unspecified without mention of intractable epilepsy', 'Epileptic attack NOS', 'EP - Epilepsy', 'Generalized convulsion', 'Epilepsy unspecified with intractable epilepsy', 'Other forms of epilepsy with intractable epilepsy', 'Epilepsy NOS', 'Epileptic disorder NOS', 'EF - Epileptic fit', 'Epilepsy (disorder)', 'EPILEPSY NEC W INTR EPIL', 'seizure disorder', 'Epilepsy NOS (disorder)', 'Other forms of epilepsy without mention of intractable epilepsy', 'Generalized fit', 'Epileptic', 'Epileptic fit', 'Epilepsy unspecified', 'Epilectic attack NOS', 'Generalised fit', 'Epileptic fits NOS', 'Generalised seizure', 'Epileptic disorder', 'Generalized seizure', 'Epileptic seizures NOS', 'Other forms of epilepsy NOS', '[X]Other epilepsy (disorder)', 'Epileptic convulsions', 'Other forms of epilepsy (disorder)', 'Epileptic convulsions NOS', 'Epileptic attack', 'EPILEPSY NOS W INTR EPIL', 'Generalised convulsion', 'Epileptic seizures', 'Other forms of epilepsy and recurrent seizures', 'EPILEP NOS W/O INTR EPIL', '[X]Other epilepsy', 'Epilepsy and recurrent seizures', 'EPILEP NEC W/O INTR EPIL', 'Other forms of epilepsy', 'Epileptic seizure (finding)', 'Other forms of epilepsy NOS (disorder)', 'Epileptic fits', 'Seizure disorder', 'Seizure disorder (disorder)', 'Becker muscular dystrophy', 'Becker muscular dystrophy X-linked recessive', 'Becker dystrophinopathy', 'benign pseudohypertrophic muscular dystrophy', 'BMD', 'benign congenital myopathy', 'muscular dystrophy Becker type', """"""""Becker's muscular dystrophy"""""""", 'muscular dystrophy pseudohypertrophic progressive Becker type', 'Duchenne muscular dystrophy', 'DMD', 'muscular dystrophy Duchenne', 'severe dystrophinopathy Duchenne type', 'Duchenne muscular dystrophy X-linked recessive', 'muscular dystrophy Duchenne type', 'muscular dystrophy pseudohypertrophic progressive Duchenne type', 'hemophilia A', 'hereditary Factor VIII deficiency disease', 'hemophilia a X-linked recessive', 'hemophilia type a', 'Subhemophilia', 'haemophilia a X-linked recessive', 'factor VIII deficiency', 'congenital factor VIII disorder', 'haemophilia type a', 'hemophilia type A', 'haemophilia type A', 'hereditary Factor VIII deficiency', 'classical haemophilia', 'autosomal hemophilia a', 'hemophilia classic', 'factor 8 deficiency', 'classic haemophilia', 'Haemophilia A', 'hemophilia A congenital', 'autosomal haemophilia a', 'hem A', 'classical hemophilia', 'HEMA', 'classic hemophilia', 'haemophilia A congenital', 'Disorder of amino acid and other organic acid metabolism', 'hemophilia B', 'haemophilia type B', 'haemophilia b X-linked recessive', 'congenital factor IX disorder', 'factor IX deficiency', 'hereditary Factor IX deficiency', 'hereditary Factor IX deficiency disease', 'congenital factor IX deficiency', 'hemophilia type B', 'Christmas disease', 'hemophilia b X-linked recessive', 'deficiency functional factor IX', 'HEMB', 'hemophilia B Leyden', 'F9 deficiency', 'haemophilia B Leyden', 'hemophilia B(M)', 'haemophilia B(M)', 'plasma thromboplastin component deficiency', 'hem B', 'factor 9 deficiency', 'aniridia', 'aplasia of iris', 'cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'nervous system disease', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'hematologic disease', 'nutritional or metabolic disease', 'disorder of visual system', 'respiratory or thoracic disease']",protein nucleic-acid complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) and has 7 investigational indications.,[],pharmgkb,other,improvement in chloride transport,,rs77010898,FALSE
CHEMBL4297517,MYL2,"BRAP, ATXN2, MAPKAPK5-AS1","LVEDV, LVEDV_BSA, LVESV_BSA, LVESV, LVSV_BSA, LVMVR, LVEDV_BSA, LVMVR, LVESV, LVEDV, LVSV, LVSV_BSA, LVESV_BSA, RVEF, RVESV_BSA, RVEDV, RVESV, RVSV, RVEDV_BSA, RVSV_BSA","",United States,MAVACAMTEN,Yes,INHIBITOR,Cardiac myosin inhibitor,"['hypertrophic cardiomyopathy', 'hypertrophic myocardiopathy', 'Cardiomyopathies Hypertrophic Obstructive', 'Hypertrophies Asymmetric Septal', 'Asymmetric Septal Hypertrophies', 'obstructive hypertrophic cardiomyopathy', 'Septal Hypertrophies Asymmetric', 'SUBVALV STENOSIS IDIOPATHIC HYPERTROPHIC', 'Hypertrophic Obstructive Cardiomyopathies', 'Cardiomyopathy hypertrophic', 'Asymmetric Septal Hypertrophy', 'hyper. obst. cardiomyopathy', 'primary hypertrophic cardiomyopathy (disorder) [Ambiguous]', 'hypertrophic obstructive cardiomyopathy', 'Septal Hypertrophy Asymmetric', 'Primary hypertrophic cardiomyopathy', 'Idiopathic Hypertrophic Subaortic Stenosis', 'Hypertrophy Asymmetric Septal', 'Hypertrophic Cardiomyopathies', 'hypertrophic subaortic stenosis', 'Obstructive cardiomyopathy', 'SUBVALV STENOSIS', 'IHSS', 'HCM - Hypertrophic cardiomyopathy', 'Hypertrophic cardiomyopathy (disorder)', 'Cardiomyopathies Hypertrophic', 'Cardiomyopathy Hypertrophic Obstructive', 'IHSSs', 'Hypertrophic Obstructive Cardiomyopathy', 'Subvalvular Stenosis Idiopathic Hypertrophic', 'Obstructive Cardiomyopathies Hypertrophic', 'Idiopathic Hypertrophic Subvalvular Stenosis', 'Hypertrophic obstructive cardiomyopathy (disorder)', 'HOCM - Hypertrophic obstructive cardiomyopathy', 'HYPERTR OBSTR CARDIOMYOP', 'Obstructive Cardiomyopathy Hypertrophic', 'HCM', 'IDIOPATHIC HYPERTROPHIC SUBVALV STENOSIS', 'familial hypertrophic cardiomyopathy', 'HCM - hypertrophic cardiomyopathy', 'heart failure', 'Weak heart', 'Heart failure NOS', 'Heart failure unspecified', 'Heart: [weak] or [failure NOS]', 'Heart failure NOS (disorder)', 'cardiac failure', 'cardiac dysfunction', 'failure heart', 'Heart failure (disorder)', 'insufficiency Cardiac', 'cardiac insufficiency', 'Myosin-6', 'MYH6', 'MYHCA', 'MyHC-alpha', 'Myosin heavy chain 6', 'Myosin heavy chain cardiac muscle alpha isoform', 'cardiomyopathy hypertrophic 1', 'ASD3', 'CMD1EE', 'CMH14', 'MYHC', 'SSS3', 'alpha-MHC', 'myosin-6', 'myHC-alpha', 'myosin heavy polypeptide 6 cardiac muscle alpha (cardiomyopathy hypertrophic 1)', 'myosin heavy chain 6', 'Myosin light chain 3', 'MYL3', 'CMLC1', 'MLC1SB', 'VLCl', 'MLC-lV/sb', 'CMH8', 'VLC1', 'MLC1V', 'Cardiac myosin light chain 1', 'Myosin light chain 1 slow-twitch muscle B/ventricular isoform', 'Ventricular myosin alkali light chain', 'Ventricular myosin light chain 1', 'Ventricular/slow twitch myosin alkali light chain', 'myosin light chain 3', 'cardiac myosin light chain 1', 'myosin light chain 3 alkali; ventricular skeletal slow', 'myosin light polypeptide 3 alkali; ventricular skeletal slow', 'ventricular myosin alkali light chain', 'ventricular myosin light chain 1', 'ventricular/slow twitch myosin alkali light chain', 'Myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'MYL2', 'MLC2', 'MLC-2', 'MLC-2v', 'MLC-2s/v', 'CMH10', 'Cardiac myosin light chain 2', 'Myosin light chain 2 slow skeletal/ventricular muscle isoform', 'Ventricular myosin light chain 2', 'cardiac ventricular myosin light chain 2', 'MFM12', 'myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'RLC of myosin', 'S15D myosin regulatory light chain 2', 'T160D myosin regulatory light chain 2', 'cardiac myosin light chain 2', 'myosin light chain 2 regulatory cardiac slow', 'myosin light polypeptide 2 regulatory cardiac slow', 'regulatory light chain of myosin', 'slow cardiac myosin regulatory light chain 2', 'ventricular myosin light chain 2', 'myosin light chain 2', 'Myosin regulatory light chain 2 atrial isoform', 'MYL7', 'MYL2A', 'MYLC2A', 'MLC-2a', 'MLC2a', 'Myosin light chain 2a', 'Myosin regulatory light chain 7', 'myosin regulatory light chain 2 atrial isoform', 'myosin light chain 2a', 'myosin regulatory light chain 7', 'myosin light chain 7 regulatory', 'myosin light polypeptide 7 regulatory', 'myosin light chain 7', 'Myosin-7B', 'MYH7B', 'KIAA1512', 'dJ756N5.1', 'MYH14', 'MHC14', 'lncMYH7b', 'Antigen MLAA-21', 'Myosin cardiac muscle beta chain', 'Myosin heavy chain 7B cardiac muscle beta isoform', 'Slow A MYH14', 'myosin-7B', 'U937-associated antigen', 'antigen MLAA-21', 'myosin heavy chain 7B cardiac muscle beta', 'myosin heavy polypeptide 7B cardiac muscle beta', 'slow A MYH14', 'myosin heavy chain 7B', 'Myosin-7', 'MYH7', 'MYHCB', 'MyHC-slow', 'MyHC-beta', 'CMD1S', 'Myosin heavy chain 7', 'Myosin heavy chain slow isoform', 'Myosin heavy chain cardiac muscle beta isoform', 'CMH1', 'CMYP7A', 'CMYP7B', 'MPD1', 'SPMD', 'SPMM', 'myosin-7', 'cardiac muscle myosin heavy chain 7 beta', 'myHC-beta', 'myhc-slow', 'myosin 7', 'myosin heavy chain beta-subunit', 'myosin heavy chain 7 cardiac muscle beta', 'myosin heavy polypeptide 7 cardiac muscle beta', 'rhabdomyosarcoma antigen MU-RMS-40.7A', 'myosin heavy chain 7', 'Myosin light chain 4', 'MYL4', 'MLC1', 'PRO1957', 'ALC1', 'AMLC', 'GT1', 'Myosin light chain 1 embryonic muscle/atrial isoform', 'Myosin light chain alkali GT-1 isoform', 'myosin atrial/fetal muscle light chain', 'atrial myosin light chain 1', 'myosin light chain 4', 'myosin light chain 4 alkali; atrial embryonic', 'myosin light polypeptide 4 alkali; atrial embryonic', 'musculoskeletal or connective tissue disease', 'cardiovascular disease']",protein complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2022 and is indicated for hypertrophic cardiomyopathy and has 1 investigational indication. This drug has a black box warning from the FDA.,['EFO_0000538'],"","","",,"",
CHEMBL4297744,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",ELX-02,No,MODULATOR,80S Ribosome modulator,"['cystic fibrosis', 'mucoviscidosis', 'pseudomonas aeruginosa susceptibility to chronic infection by in cystic fibrosis', 'cystic fibrosis lung disease modifier of', 'CF', 'Alport syndrome', 'hereditary nephritis', 'Alport deafness-nephropathy', """"""""Alport's syndrome"""""""", 'kidney disease', 'renal system disease', 'Kidney Disorder', 'disease or disorder of kidney', 'renal disorder', 'disorder of kidney', 'renal disease', 'disease of kidney', 'nephropathy', 'kidney diseases', 'kidney disorder', 'kidney disease or disorder', 'cystinosis', 'cystine storage disease', 'Protein defect of cystin transport', 'cystine diathesis', 'Cystinoses', 'cystine disease', 'genetic disorder', 'genetic disease', 'genetic condition', 'inherited disease', 'hereditary diseases', 'inherited genetic disease', 'hereditary disease or disorder', 'hereditary disease', 'molecular disease', 'Mendelian disease', 'inborn disorder', 'familial disorder', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'urinary system disease', 'nutritional or metabolic disease']",protein nucleic-acid complex,Unknown drug with a maximum clinical trial phase of II (across all indications) and has 5 investigational indications.,[],"","","",,"",
CHEMBL4297789,RPL6,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVEDV, LVESV, LVEDV_BSA, LVMVR, LVSV, LVSV_BSA, LVSV, LVESV, LVEDV_BSA, LVMVR, LVSV_BSA, LVESV_BSA, LVEDV, RVEDV_BSA, RVSV, RVEDV, RVESV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVESV_BSA, RVEDV_BSA, RVSV_BSA, RVEF, RVESV","","",MT-3724,No,INHIBITOR,80S Ribosome inhibitor,"['non-Hodgkins lymphoma', """"""""non-Hodgkin's lymphoma"""""""", 'NHL', 'non-Hodgkin lymphoma', """"""""non-Hodgkin's lymphoma (NHL)"""""""", 'lymphoid leukemia', 'lymphocytic leukaemia', 'lymphogenous leukaemia', 'lymphoid leukemia (disease)', 'lymphogenous leukemia', 'leukemia LYMPHOCYTIC malignant', 'lymphoid leukaemia (disease)', 'subacute lymphoid leukemia', 'lymphocytic leukemia', 'subacute lymphoid leukaemia', 'diffuse large B-cell lymphoma', 'DLBCL', 'chronic lymphocytic leukemia', 'B-cell lymphocytic leukaemia', 'CLL', 'B-CLL', 'BCLL', 'chronic lymphogenous leukaemia', 'B cell lymphocytic leukemia', 'chronic lymphatic leukaemia', 'B cell CLL', 'B-cell lymphocytic leukemia', 'small lymphocytic lymphoma', 'B-cell chronic lymphoid leukaemia', 'lymphoplasmacytic leukaemia', 'B-cell chronic lymphocytic leukemia', 'B-cell chronic lymphogenous leukemia', 'B-cell chronic lymphogenous leukaemia', 'B-cell chronic lymphoid leukemia', 'B cell chronic lymphocytic leukaemia', 'chronic B-cell lymphocytic leukaemia', 'B cell lymphocytic leukaemia', 'chronic lymphocytic leukemia (CLL)', 'B-cell CLL', 'chronic lymphocytic leukaemia (CLL)', 'chronic lymphatic leukemia', 'chronic B-cell lymphocytic leukemia', 'B cell chronic lymphocytic leukemia', 'lymphoplasmacytic leukemia', 'hematopoeitic - chronic lymphocytic leukemia (CLL)', 'hematopoeitic - chronic lymphocytic leukaemia (CLL)', 'chronic lymphogenous leukemia', 'chronic lymphocytic leukaemia', 'leukemia chronic LYMPHOCYTIC', 'leukemia chronic lymphatic', 'leukemia lymphocytic chronic', 'Large ribosomal subunit protein eL8', 'RPL7A', 'SURF-3', 'SURF3', 'TRUP', 'L7A', 'eL8', '60S ribosomal protein L7a', 'PLA-X polypeptide', 'Surfeit locus protein 3', 'surfeit 3', 'surfeit locus protein 3', 'thyroid hormone receptor uncoupling protein', 'large ribosomal subunit protein eL8', 'ribosomal protein L7a', 'Small ribosomal subunit protein eS8', 'RPS8', 'OK/SW-cl.83', 'S8', 'eS8', '40S ribosomal protein S8', 'small ribosomal subunit protein eS8', 'ribosomal protein S8', 'Small ribosomal subunit protein eS7', 'RPS7', 'S7', 'eS7', '40S ribosomal protein S7', 'DBA8', 'small ribosomal subunit protein eS7', 'ribosomal protein S7', 'Large ribosomal subunit protein uL22', 'RPL17', 'rpL23', 'L17', 'uL22', '60S ribosomal protein L17', '60S ribosomal protein L23', 'PD-1', 'RPL23', 'large ribosomal subunit protein uL22', 'gene encoding putative NFkB activating protein', 'ribosomal protein L17', 'Large ribosomal subunit protein eL22', 'RPL22', 'EAP', 'L22', 'eL22', '60S ribosomal protein L22', 'EBER-associated protein', 'Epstein-Barr virus small RNA-associated protein', 'Heparin-binding protein HBp15', 'HBP15', 'HBP15/L22', 'large ribosomal subunit protein eL22', 'Epstein-Barr-encoded RNA-associated protein', 'heparin-binding protein 15', 'heparin-binding protein HBp15', 'ribosomal protein L22', 'Large ribosomal subunit protein uL1', 'RPL10A', 'NEDD6', 'NEDD-6', 'Csa-19', 'L10A', 'uL1', '60S ribosomal protein L10a', 'CSA-19', 'Neural precursor cell expressed developmentally down-regulated protein 6', 'CSA19', 'large ribosomal subunit protein uL1', 'neural precursor cell expressed developmentally down-regulated protein 6', 'ribosomal protein L10a', 'Large ribosomal subunit protein uL16', 'RPL10', 'DXS648E', 'QM', 'NOV', 'DXS648', 'FLJ23544', 'L10', 'uL16', '60S ribosomal protein L10', 'Laminin receptor homolog', 'Protein QM', 'Ribosomal protein L10', 'Tumor suppressor QM', 'AUTSX5', 'MRXS35', 'large ribosomal subunit protein uL16', 'Wilms tumor-related protein', 'laminin receptor homolog', 'tumor suppressor QM', 'ribosomal protein L10', 'Small ribosomal subunit protein eS27', 'RPS27', 'MPS1', 'MPS-1', 'S27', 'eS27', '40S ribosomal protein S27', 'Metallopan-stimulin 1', 'metallopanstimulin 1', 'DBA17', 'small ribosomal subunit protein eS27', 'metallopan-stimulin 1', 'ribosomal protein S27', 'Small ribosomal subunit protein uS17', 'RPS11', 'S11', 'uS17', '40S ribosomal protein S11', 'small ribosomal subunit protein uS17', 'ribosomal protein S11', 'Small ribosomal subunit protein eS10', 'RPS10', 'MGC88819', 'S10', 'eS10', '40S ribosomal protein S10', 'DBA9', 'small ribosomal subunit protein eS10', 'ribosomal protein S10', 'Small ribosomal subunit protein uS10', 'RPS20', 'S20', 'uS10', '40S ribosomal protein S20', 'small ribosomal subunit protein uS10', 'ribosomal protein S20', 'Large ribosomal subunit protein uL3', 'RPL3', 'OK/SW-cl.32', 'TARBP-B', 'L3', 'uL3', '60S ribosomal protein L3', 'HIV-1 TAR RNA-binding protein B', 'ASC-1', 'large ribosomal subunit protein uL3', 'ribosomal protein L3', 'Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'Ubiquitin-like protein FUBI', 'Small ribosomal subunit protein eS30', 'FAU', 'RPS30', 'FLJ22986', 'Fub1', 'Fubi', 'MNSFbeta', 'asr1', 'S30', 'eS30', 'FAU ubiquitin like and ribosomal protein S30 fusion', '40S ribosomal protein S30', 'ribosomal protein S30', 'Monoclonal nonspecific suppressor factor beta', 'FAU1', 'ubiquitin-like FUBI-ribosomal protein eS30 fusion protein', 'FAU ubiquitin-like and ribosomal protein S30', 'FAU-encoded ubiquitin-like protein', 'FBR-MuSV-associated ubiquitously expressed', 'Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived)', 'monoclonal nonspecific suppressor factor beta', 'small ribosomal subunit protein eS30', 'ubiquitin-like protein fubi and ribosomal protein S30', 'ubiquitin-like-S30 fusion protein', 'Small ribosomal subunit protein eS6', 'RPS6', 'OK/SW-cl.2', 'S6', 'eS6', '40S ribosomal protein S6', 'Phosphoprotein NP33', 'phosphoprotein NP33', 'small ribosomal subunit protein eS6', 'ribosomal protein S6', 'Large ribosomal subunit protein uL2', 'RPL8', 'L8', 'uL2', '60S ribosomal protein L8', 'large ribosomal subunit protein uL2', 'ribosomal protein L8', 'Ubiquitin-ribosomal protein eS31 fusion protein', 'Ubiquitin', 'Small ribosomal subunit protein eS31', 'RPS27A', 'UBA80', 'UBCEP1', 'UBCEP80', 'Uba80', 'S27A', 'eS31', 'Ubiquitin carboxyl extension protein 80', '40S ribosomal protein S27a', 'ubiquitin carboxyl extension protein 80', 'CEP80', 'HEL112', 'UBC', 'ubiquitin-ribosomal protein eS31 fusion protein', 'epididymis luminal protein 112', 'ubiquitin C', 'ubiquitin and ribosomal protein S27a', 'ubiquitin-40S ribosomal protein S27a', 'ubiquitin-CEP80', 'ribosomal protein S27a', 'Large ribosomal subunit protein eL13', 'RPL13', 'BBC1', 'OK/SW-cl.46', 'D16S444E', 'L13', 'eL13', '60S ribosomal protein L13', 'Breast basic conserved protein 1', 'breast basic conserved 1', 'D16S44E', 'SEMDIST', 'large ribosomal subunit protein eL13', 'breast basic conserved protein 1', 'ribosomal protein L13', 'Large ribosomal subunit protein uL15', 'RPL27A', 'L27A', 'uL15', '60S ribosomal protein L27a', 'large ribosomal subunit protein uL15', 'ribosomal protein L27a', 'Large ribosomal subunit protein uL10', 'RPLP0', 'PRLP0', 'P0', 'L10E', 'RPP0', 'LP0', 'uL10', '60S acidic ribosomal protein P0', '60S ribosomal protein L10E', 'neutral ribosomal phosphoprotein P0', 'large ribosomal subunit protein uL10', 'acidic ribosomal phosphoprotein P0', 'ribosomal protein large P0', 'ribosomal protein lateral stalk subunit P0', 'Small ribosomal subunit protein uS12', 'RPS23', 'S23', 'uS12', '40S ribosomal protein S23', 'BTDD', 'MABAS', 'MCINS', 'PAMAS', 'small ribosomal subunit protein uS12', 'homolog of yeast ribosomal protein S28', 'ribosomal protein S23', 'Large ribosomal subunit protein eL36', 'RPL36', 'DKFZp566B023', 'L36', 'eL36', '60S ribosomal protein L36', 'large ribosomal subunit protein eL36', 'ribosomal protein L36', 'Small ribosomal subunit protein eS19', 'RPS19', 'S19', 'eS19', 'DBA', '40S ribosomal protein S19', 'Diamond-Blackfan anemia', 'DBA1', 'LOH19CR1', 'small ribosomal subunit protein eS19', 'loss of heterozygosity on chromosome 19 region 1', 'loss of heterozygosity 19 chromosomal region 1', 'ribosomal protein S19', 'Large ribosomal subunit protein eL38', 'RPL38', 'L38', 'eL38', '60S ribosomal protein L38', 'large ribosomal subunit protein eL38', 'ribosomal protein L38', 'Large ribosomal subunit protein uL24', 'RPL26', 'L26', 'uL24', '60S ribosomal protein L26', 'DBA11', 'large ribosomal subunit protein uL24', 'ribosomal protein L26', 'Small ribosomal subunit protein eS21', 'RPS21', 'S21', 'eS21', '40S ribosomal protein S21', '8.2 kDa differentiation factor', 'HLDF', 'small ribosomal subunit protein eS21', 'human leukemia differentiation factor', 'ribosomal protein S21', 'Small ribosomal subunit protein uS13', 'RPS18', 'D6S218E', 'Ke3', 'KE3', 'KE-3', 'HKE3', 'S18', 'uS13', '40S ribosomal protein S18', 'Ke-3', 'small ribosomal subunit protein uS13', 'rhabdomyosarcoma antigen MU-RMS-40.21', 'ribosomal protein S18', 'Small ribosomal subunit protein uS11', 'RPS14', 'PRO2640', 'EMTB', 'S14', 'uS11', '40S ribosomal protein S14', 'emetine resistance', 'small ribosomal subunit protein uS11', 'ribosomal protein S14', 'Large ribosomal subunit protein uL5', 'RPL11', 'L11', 'uL5', '60S ribosomal protein L11', 'CLL-associated antigen KW-12', 'DBA7', 'GIG34', 'large ribosomal subunit protein uL5', 'cell growth-inhibiting protein 34', 'ribosomal protein L11', 'Small ribosomal subunit protein eS1', 'RPS3A', 'FTE1', 'MFTL', 'Fte-1', 'S3A', 'eS1', '40S ribosomal protein S3a', 'v-fos transformation effector protein', 'small ribosomal subunit protein eS1', 'fte-1', 'v-fos transformation effector protein 1', 'ribosomal protein S3A', 'Large ribosomal subunit protein uL13', 'RPL13A', 'L13A', 'uL13', '23 kDa highly basic protein', '60S ribosomal protein L13a', 'TSTA1', 'large ribosomal subunit protein uL13', 'epididymis secretory sperm binding protein', 'highly basic protein 23 kDa', 'tissue specific transplantation antigen 1', 'ribosomal protein L13a', 'Large ribosomal subunit protein eL31', 'RPL31', 'L31', 'eL31', '60S ribosomal protein L31', 'large ribosomal subunit protein eL31', 'ribosomal protein L31', 'Small ribosomal subunit protein eS4 Y isoform 1', 'RPS4Y1', 'RPS4Y', 'PRO2646', 'MGC5070', 'MGC119100', 'S4', '40S ribosomal protein S4', 'ribosomal protein S4Y', '40S ribosomal protein S4 Y', 'small ribosomal subunit protein eS4 Y isoform 1', 'small ribosomal subunit protein eS4 Y', 'ribosomal protein S4 Y-linked', 'small ribosomal subunit protein eS4', 'ribosomal protein S4 Y-linked 1', 'Large ribosomal subunit protein uL18', 'RPL5', 'MSTP030', 'L5', 'PPP1R135', 'uL18', '60S ribosomal protein L5', 'protein phosphatase 1 regulatory subunit 135', 'large ribosomal subunit protein uL18', 'ribosomal protein L5', 'Small ribosomal subunit protein uS14', 'RPS29', 'S29', 'uS14', '40S ribosomal protein S29', 'DBA13', 'small ribosomal subunit protein uS14', 'ribosomal protein S29', 'Large ribosomal subunit protein eL19', 'RPL19', 'FLJ27452', 'MGC71997', 'DKFZp779D216', 'L19', 'eL19', '60S ribosomal protein L19', 'ribosomal protein L19 cytosolic N-terminus truncated', 'large ribosomal subunit protein eL19', 'ribosomal protein L19', 'Large ribosomal subunit protein eL14', 'RPL14', 'L14', 'hRL14', 'RL14', 'CTG-B33', 'eL14', '60S ribosomal protein L14', 'CAG-ISL 7', 'CAG-ISL-7', 'large ribosomal subunit protein eL14', 'ribosomal protein L14', 'Large ribosomal subunit protein uL29', 'RPL35', 'L35', 'uL29', '60S ribosomal protein L35', 'DBA19', 'large ribosomal subunit protein uL29', 'ribosomal protein L35', 'Large ribosomal subunit protein uL11', 'RPL12', 'L12', 'uL11', '60S ribosomal protein L12', 'large ribosomal subunit protein uL11', 'ribosomal protein L12', 'Large ribosomal subunit protein eL20', 'RPL18A', 'L18A', 'eL20', '60S ribosomal protein L18a', 'ribosomal protein L18a-like protein', 'large ribosomal subunit protein eL20', 'ribosomal protein L18a', 'Large ribosomal subunit protein eL29', 'RPL29', 'HIP', 'HUMRPL29', 'L29', 'eL29', '60S ribosomal protein L29', 'Cell surface heparin-binding protein HIP', 'heparin/heparan sulfate-interacting protein', 'HP/HS-interacting protein', 'heparin/heparan sulfate-binding protein', 'cell surface heparin-binding protein HIP', 'RPL29P10', 'RPL29_3_370', 'large ribosomal subunit protein eL29', 'ribosomal protein YL43 homologue', 'ribosomal protein L29', 'Small ribosomal subunit protein uS4', 'RPS9', 'S9', 'uS4', '40S ribosomal protein S9', 'small ribosomal subunit protein uS4', 'ribosomal protein S9', 'B-lymphocyte antigen CD20', 'MS4A1', 'CD20', 'B1', 'Bp35', 'FMC7', 'B-lymphocyte surface antigen B1', 'Leukocyte surface antigen Leu-16', 'Membrane-spanning 4-domains subfamily A member 1', 'CVID5', 'LEU-16', 'B-lymphocyte cell-surface antigen B1', 'CD20 antigen', 'CD20 receptor', 'leukocyte surface antigen Leu-16', 'membrane-spanning 4-domains subfamily A member 1', 'membrane spanning 4-domains A1', 'Large ribosomal subunit protein uL4', 'RPL4', 'RPL1', 'L4', 'uL4', '60S ribosomal protein L1', '60S ribosomal protein L4', 'large ribosomal subunit protein uL4', 'ribosomal protein L4', 'Large ribosomal subunit protein eL15', 'RPL15', 'EC45', 'TCBAP0781', 'RPLY10', 'RPYL10', 'L15', 'eL15', '60S ribosomal protein L15', 'DBA12', 'large ribosomal subunit protein eL15', 'ribosomal protein L15', 'Small ribosomal subunit protein eS24', 'RPS24', 'S24', 'eS24', '40S ribosomal protein S24', 'DBA3', 'small ribosomal subunit protein eS24', 'ribosomal protein S24', 'Small ribosomal subunit protein uS15', 'RPS13', 'S13', 'uS15', '40S ribosomal protein S13', 'small ribosomal subunit protein uS15', 'ribosomal protein S13', 'Large ribosomal subunit protein P1', 'RPLP1', 'RRP1', 'LP1', 'P1', '60S acidic ribosomal protein P1', 'RPP1', 'large ribosomal subunit protein P1', 'acidic ribosomal phosphoprotein P1', 'ribosomal protein large P1', 'ribosomal protein lateral stalk subunit P1', 'Small ribosomal subunit protein uS7', 'Small ribosomal subunit protein uS7 N-terminally processed', 'RPS5', 'S5', 'uS7', '40S ribosomal protein S5', '40S ribosomal protein S5 N-terminally processed', 'small ribosomal subunit protein uS7', 'ribosomal protein S5', 'Large ribosomal subunit protein eL21', 'RPL21', 'L21', 'FLJ27458', 'MGC71252', 'MGC104274', 'MGC104275', 'DKFZp686C06101', 'eL21', '60S ribosomal protein L21', 'HYPT12', 'large ribosomal subunit protein eL21', 'ribosomal protein L21', 'Large ribosomal subunit protein eL27', 'RPL27', 'L27', 'eL27', '60S ribosomal protein L27', 'DBA16', 'large ribosomal subunit protein eL27', 'ribosomal protein L27', 'Large ribosomal subunit protein eL32', 'RPL32', 'PP9932', 'L32', 'eL32', '60S ribosomal protein L32', 'large ribosomal subunit protein eL32', 'ribosomal protein L32', 'Large ribosomal subunit protein eL39', 'RPL39', 'L39', 'eL39', '60S ribosomal protein L39', 'RPL39P42', 'RPL39_23_1806', 'large ribosomal subunit protein eL39', 'ribosomal protein L39', 'Large ribosomal subunit protein eL34', 'RPL34', 'L34', 'eL34', '60S ribosomal protein L34', 'large ribosomal subunit protein eL34', 'leukemia-associated protein', 'ribosomal protein L34', 'Small ribosomal subunit protein uS2', 'RPSA', 'LAMBR', 'LAMR1', '37LRP', 'LRP/LR', '67LR', 'LamR', 'LBP/p40', 'LRP', 'p40', 'SA', 'uS2', '37 kDa laminin receptor precursor', '37/67 kDa laminin receptor', '40S ribosomal protein SA', '67 kDa laminin receptor', 'Colon carcinoma laminin-binding protein', 'Laminin receptor 1', 'Laminin-binding protein precursor p40', 'Multidrug resistance-associated protein MGr1-Ag', 'NEM/1CHD4', 'ICAS', 'LBP', 'lamR', 'small ribosomal subunit protein uS2', '37 kDa laminin receptor', 'colon carcinoma laminin-binding protein', 'laminin receptor 1 (67kD ribosomal protein SA)', 'laminin-binding protein precursor p40', 'multidrug resistance-associated protein MGr1-Ag', 'ribosomal protein SA', 'Large ribosomal subunit protein uL30', 'RPL7', 'humL7-1', 'L7', 'uL30', '60S ribosomal protein L7', 'large ribosomal subunit protein uL30', 'ribosomal protein L7', 'Large ribosomal subunit protein eL37', 'RPL37', 'L37', 'eL37', '60S ribosomal protein L37', 'G1.16', '60S ribosomal protein L37a', 'large ribosomal subunit protein eL37', 'ribosomal protein L37', 'Large ribosomal subunit protein uL23', 'RPL23A', 'L23A', 'uL23', '60S ribosomal protein L23a', 'MDA20', 'large ribosomal subunit protein uL23', 'melanoma differentiation-associated gene 20', 'ribosomal protein L23a', 'Large ribosomal subunit protein eL28', 'RPL28', 'FLJ43307', 'L28', 'eL28', '60S ribosomal protein L28', 'large ribosomal subunit protein eL28', 'ribosomal protein L28', 'Small ribosomal subunit protein uS19', 'RPS15', 'RIG', 'MGC111130', 'S15', 'uS19', '40S ribosomal protein S15', 'RIG protein', 'homolog of rat insulinoma', 'insulinoma protein', 'small ribosomal subunit protein uS19', 'ribosomal protein S15', 'Large ribosomal subunit protein eL24', 'RPL24', 'L24', 'eL24', '60S ribosomal protein L24', '60S ribosomal protein L30', 'HEL-S-310', 'large ribosomal subunit protein eL24', 'epididymis secretory protein Li 310', 'ribosomal protein L30', 'ribosomal protein L24', 'Large ribosomal subunit protein eL6', 'RPL6', 'TXREB1', 'TaxREB107', 'TAXREB107', 'L6', 'eL6', '60S ribosomal protein L6', 'Neoplasm-related protein C140', 'Tax-responsive enhancer element-binding protein 107', 'SHUJUN-2', 'large ribosomal subunit protein eL6', 'DNA-binding protein TAXREB107', 'neoplasm-related protein C140', 'tax-responsive enhancer element-binding protein 107', 'ribosomal protein L6', 'Large ribosomal subunit protein eL18', 'RPL18', 'L18', 'eL18', '60S ribosomal protein L18', 'DBA18', 'large ribosomal subunit protein eL18', 'ribosomal protein L18', 'Small ribosomal subunit protein eS17', 'RPS17', 'RPS17L', 'RPS17L1', 'RPS17L2', 'MGC72007', 'S17', 'eS17', '40S ribosomal protein S17', 'DBA4', 'small ribosomal subunit protein eS17', 'ribosomal protein S17', 'Small ribosomal subunit protein eS4 X isoform', 'RPS4X', 'CCG2', 'RPS4', 'SCAR', 'DXS306', 'SCR10', 'FLJ40595', 'eS4', 'Single copy abundant mRNA protein', '40S ribosomal protein S4 X isoform', 'ribosomal protein S4X isoform', 'single-copy abundant mRNA', 'cell cycle gene 2', 'small ribosomal subunit protein eS4 X isoform', 'single copy abundant mRNA protein', 'ribosomal protein S4 X-linked', 'Large ribosomal subunit protein eL42', 'RPL36A', 'RPL44', 'GIG15', 'MIG6', 'L36A', 'eL42', '60S ribosomal protein L36a', '60S ribosomal protein L44', 'Cell growth-inhibiting gene 15 protein', 'Cell migration-inducing gene 6 protein', 'L44L', 'large ribosomal subunit protein eL42', 'L44-like ribosomal protein', 'cell growth-inhibiting gene 15 protein', 'cell migration-inducing gene 6 protein', 'dJ164F3.3 (ribosomal protein L44)', 'ribosomal protein L36a', 'Small ribosomal subunit protein uS3', 'RPS3', 'OK/SW-cl.26', 'FLJ26283', 'FLJ27450', 'MGC87870', 'S3', 'uS3', '40S ribosomal protein S3', 'IMR-90 ribosomal protein S3', 'small ribosomal subunit protein uS3', 'ribosomal protein S3', 'Large ribosomal subunit protein eL33', 'RPL35A', 'GIG33', 'L35A', 'eL33', '60S ribosomal protein L35a', 'Cell growth-inhibiting gene 33 protein', 'DBA5', 'large ribosomal subunit protein eL33', 'cell growth-inhibiting gene 33 protein', 'ribosomal protein L35a', 'Large ribosomal subunit protein uL14', 'rpL17', 'L23', 'uL14', 'large ribosomal subunit protein uL14', 'ribosomal protein L23', 'Large ribosomal subunit protein uL6', 'RPL9', 'OK/SW-cl.103', 'L9', 'uL6', '60S ribosomal protein L9', 'NPC-A-16', 'large ribosomal subunit protein uL6', 'ribosomal protein L9', 'Small ribosomal subunit protein eS28', 'RPS28', 'S28', 'eS28', '40S ribosomal protein S28', 'DBA15', 'small ribosomal subunit protein eS28', 'ribosomal protein S28', 'Small ribosomal subunit protein eS12', 'RPS12', 'S12', 'eS12', '40S ribosomal protein S12', 'small ribosomal subunit protein eS12', 'ribosomal protein S12', 'Small ribosomal subunit protein uS8', 'RPS15A', 'OK/SW-cl.82', 'S15A', 'uS8', '40S ribosomal protein S15a', 'DBA20', 'S15a', 'small ribosomal subunit protein uS8', 'up-regulated by HBV X protein', 'ribosomal protein S15a', 'Large ribosomal subunit protein eL43', 'RPL37A', 'L37A', 'eL43', 'large ribosomal subunit protein eL43', 'ribosomal protein L37a', 'Small ribosomal subunit protein eS25', 'RPS25', 'S25', 'eS25', '40S ribosomal protein S25', 'small ribosomal subunit protein eS25', 'ribosomal protein S25', 'Small ribosomal subunit protein uS9', 'RPS16', 'S16', 'uS9', '40S ribosomal protein S16', 'small ribosomal subunit protein uS9', 'ribosomal protein S16', 'Small ribosomal subunit protein uS5', 'RPS2', 'LLREP3', 'S2', 'uS5', '40S ribosomal protein S2', 'Protein LLRep3', 'small ribosomal subunit protein uS5', 'OK/KNS-cl.6', 'protein LLRep3', 'ribosomal protein S2', 'Small ribosomal subunit protein eS26', 'RPS26', 'S26', 'eS26', '40S ribosomal protein S26', 'DBA10', 'small ribosomal subunit protein eS26', 'ribosomal protein S26', 'Small ribosomal subunit protein eS32', 'RPL41', 'L41', 'eL41', '60S ribosomal protein L41', 'HG12', 'Large ribosomal subunit protein eL41', 'small ribosomal subunit protein eS32', 'HG12 protein', 'homologue of yeast ribosomal protein YL41', 'large ribosomal subunit protein eL41', 'ribosomal protein L41', 'Large ribosomal subunit protein eL30', 'RPL30', 'L30', 'eL30', 'large ribosomal subunit protein eL30', 'hematologic disease', 'genetic familial or congenital disease', 'cancer or benign tumor', 'immune system disease']",protein nucleic-acid complex,Unknown drug with a maximum clinical trial phase of II (across all indications) and has 4 investigational indications.,[],"","","",,"",
CHEMBL4594304,MYL2,"BRAP, ATXN2, MAPKAPK5-AS1","LVEDV, LVEDV_BSA, LVESV_BSA, LVESV, LVSV_BSA, LVMVR, LVEDV_BSA, LVMVR, LVESV, LVEDV, LVSV, LVSV_BSA, LVESV_BSA, RVEF, RVESV_BSA, RVEDV, RVESV, RVSV, RVEDV_BSA, RVSV_BSA","","",DANICAMTIV,Yes,ACTIVATOR,Cardiac myosin activator,"['dilated cardiomyopathy', 'DCM - Dilated cardiomyopathy', 'Congestive cardiomyopathy', 'Idiopathic Cardiomyopathies Familial', 'Congestive Cardiomyopathies', 'Primary dilated cardiomyopathy', 'Cardiomyopathies Familial Idiopathic', 'Congestive dilated cardiomyopathy', 'Familial Idiopathic Cardiomyopathy', 'Cardiomyopathies Dilated', 'COCM - Congestive cardiomyopathy', 'Idiopathic Cardiomyopathy Familial', 'Cardiomyopathy Dilated with Conduction Deffect1', 'Cardiomyopathy Dilated CMD1A', 'Cardiomyopathies Congestive', 'Cardiomyopathy Dilated LMNA', 'primary dilated cardiomyopathy (disorder)', 'CCM - Congestive cardiomyopathy', 'Dilated Cardiomyopathies', 'Familial Idiopathic Cardiomyopathies', 'Cardiomyopathy Familial Idiopathic', 'DCM', 'Cardiomyopathy Dilated', 'Congestive cardiomyopathy (disorder)', 'Cardiomyopathy Congestive', 'familial dilated cardiomyopathy', 'primary dilated cardiomyopathy', 'congestive cardiomyopathy', 'idiopathic dilation cardiomyopathy', 'Myosin-6', 'MYH6', 'MYHCA', 'MyHC-alpha', 'Myosin heavy chain 6', 'Myosin heavy chain cardiac muscle alpha isoform', 'cardiomyopathy hypertrophic 1', 'ASD3', 'CMD1EE', 'CMH14', 'MYHC', 'SSS3', 'alpha-MHC', 'myosin-6', 'myHC-alpha', 'myosin heavy polypeptide 6 cardiac muscle alpha (cardiomyopathy hypertrophic 1)', 'myosin heavy chain 6', 'Myosin light chain 3', 'MYL3', 'CMLC1', 'MLC1SB', 'VLCl', 'MLC-lV/sb', 'CMH8', 'VLC1', 'MLC1V', 'Cardiac myosin light chain 1', 'Myosin light chain 1 slow-twitch muscle B/ventricular isoform', 'Ventricular myosin alkali light chain', 'Ventricular myosin light chain 1', 'Ventricular/slow twitch myosin alkali light chain', 'myosin light chain 3', 'cardiac myosin light chain 1', 'myosin light chain 3 alkali; ventricular skeletal slow', 'myosin light polypeptide 3 alkali; ventricular skeletal slow', 'ventricular myosin alkali light chain', 'ventricular myosin light chain 1', 'ventricular/slow twitch myosin alkali light chain', 'Myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'MYL2', 'MLC2', 'MLC-2', 'MLC-2v', 'MLC-2s/v', 'CMH10', 'Cardiac myosin light chain 2', 'Myosin light chain 2 slow skeletal/ventricular muscle isoform', 'Ventricular myosin light chain 2', 'cardiac ventricular myosin light chain 2', 'MFM12', 'myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'RLC of myosin', 'S15D myosin regulatory light chain 2', 'T160D myosin regulatory light chain 2', 'cardiac myosin light chain 2', 'myosin light chain 2 regulatory cardiac slow', 'myosin light polypeptide 2 regulatory cardiac slow', 'regulatory light chain of myosin', 'slow cardiac myosin regulatory light chain 2', 'ventricular myosin light chain 2', 'myosin light chain 2', 'Myosin regulatory light chain 2 atrial isoform', 'MYL7', 'MYL2A', 'MYLC2A', 'MLC-2a', 'MLC2a', 'Myosin light chain 2a', 'Myosin regulatory light chain 7', 'myosin regulatory light chain 2 atrial isoform', 'myosin light chain 2a', 'myosin regulatory light chain 7', 'myosin light chain 7 regulatory', 'myosin light polypeptide 7 regulatory', 'myosin light chain 7', 'Myosin-7B', 'MYH7B', 'KIAA1512', 'dJ756N5.1', 'MYH14', 'MHC14', 'lncMYH7b', 'Antigen MLAA-21', 'Myosin cardiac muscle beta chain', 'Myosin heavy chain 7B cardiac muscle beta isoform', 'Slow A MYH14', 'myosin-7B', 'U937-associated antigen', 'antigen MLAA-21', 'myosin heavy chain 7B cardiac muscle beta', 'myosin heavy polypeptide 7B cardiac muscle beta', 'slow A MYH14', 'myosin heavy chain 7B', 'Myosin-7', 'MYH7', 'MYHCB', 'MyHC-slow', 'MyHC-beta', 'CMD1S', 'Myosin heavy chain 7', 'Myosin heavy chain slow isoform', 'Myosin heavy chain cardiac muscle beta isoform', 'CMH1', 'CMYP7A', 'CMYP7B', 'MPD1', 'SPMD', 'SPMM', 'myosin-7', 'cardiac muscle myosin heavy chain 7 beta', 'myHC-beta', 'myhc-slow', 'myosin 7', 'myosin heavy chain beta-subunit', 'myosin heavy chain 7 cardiac muscle beta', 'myosin heavy polypeptide 7 cardiac muscle beta', 'rhabdomyosarcoma antigen MU-RMS-40.7A', 'myosin heavy chain 7', 'Myosin light chain 4', 'MYL4', 'MLC1', 'PRO1957', 'ALC1', 'AMLC', 'GT1', 'Myosin light chain 1 embryonic muscle/atrial isoform', 'Myosin light chain alkali GT-1 isoform', 'myosin atrial/fetal muscle light chain', 'atrial myosin light chain 1', 'myosin light chain 4', 'myosin light chain 4 alkali; atrial embryonic', 'myosin light polypeptide 4 alkali; atrial embryonic', 'musculoskeletal or connective tissue disease', 'cardiovascular disease']",protein complex,Small molecule drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL4650521,PTPN11,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVESV_BSA, LVSV, LVMVR, LVESV, LVEDV, LVEDV_BSA, LVSV_BSA, LVSV, LVEDV_BSA, LVEDV, LVESV, LVSV_BSA, LVESV_BSA, LVMVR, RVEDV, RVEDV_BSA, RVSV, RVESV_BSA, RVESV, RVSV_BSA, RVEF, RVSV_BSA, RVEDV_BSA, RVSV, RVESV_BSA, RVEDV, RVESV","","",BATOPROTAFIB,No,INHIBITOR,Protein-tyrosine phosphatase 2C inhibitor,"['metastatic malignant neoplasm', 'malignant metastatic neoplasm', 'metastatic neoplasm malignant', 'metastatic cancer', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'Tyrosine-protein phosphatase non-receptor type 11', 'PTPN11', 'PTP2C', 'SHPTP2', 'PTP-1D', 'PTP-2C', 'SHP-2', 'Shp2', 'BPTP3', 'SH-PTP2', 'SHP2', 'Protein-tyrosine phosphatase 1D', 'Protein-tyrosine phosphatase 2C', 'SH-PTP3', 'SH2 domain-containing protein tyrosine phosphatase 2', 'CFC', 'JMML', 'METCDS', 'NS1', 'tyrosine-protein phosphatase non-receptor type 11', 'protein-tyrosine phosphatase 1D', 'protein-tyrosine phosphatase 2C', 'protein tyrosine phosphatase non-receptor type 11', 'cancer or benign tumor']",single protein,Small molecule drug with a maximum clinical trial phase of I and has 1 investigational indication.,[],"","","",,"",
CHEMBL5095028,MAPKAPK5,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVEDV_BSA, LVESV_BSA, LVMVR, LVEDV, LVESV, LVSV, LVSV_BSA, LVMVR, LVEDV, LVESV, LVSV_BSA, LVEDV_BSA, LVSV, LVESV_BSA, RVEDV, RVESV_BSA, RVEF, RVEDV_BSA, RVSV, RVESV, RVSV_BSA, RVSV_BSA, RVESV, RVSV, RVEDV, RVEDV_BSA, RVESV_BSA","","",GLPG-0259,No,INHIBITOR,MAP kinase-activated protein kinase 5 inhibitor,"['rheumatoid arthritis', 'atrophic arthritis', 'Arthritis Rheumatoid', 'Rheumatoid arthritis NOS', 'rheumatoid arthritis progression of', 'Rheumatic gout', 'RA', 'Arthritis or polyarthritis rheumatic', 'Rheumatoid arthritis NOS (disorder)', 'Chronic rheumatic arthritis', 'Proliferative arthritis', 'Rheumatoid disease', 'RA - Rheumatoid arthritis', 'Rheumatoid arthritis (disorder)', 'RhA - Rheumatoid arthritis', 'arthritis rheumatoid', 'autoimmune arthritis', 'arthritis or polyarthritis rheumatic', 'atrophic Arthritis', 'rheumatoid arthritis susceptibility to', 'MAP kinase-activated protein kinase 5', 'MAPKAPK5', 'PRAK', 'MAPK-activated protein kinase 5', 'MAPKAP kinase 5', 'MAPKAP-K5', 'MAPKAPK-5', 'MK-5', 'MK5', 'p38-regulated/activated protein kinase', 'NCFD', 'mitogen-activated protein kinase-activated protein kinase 5', 'MAPK activated protein kinase 5', 'musculoskeletal or connective tissue disease', 'immune system disease']",single protein,Small molecule drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,decreased response,,rs678849,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,decreased likelihood of response,,rs2283265,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,decreased response to disulfiram treatment for cocaine dependence,,rs28363170,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,increased response,,rs1801133,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,increased likelihood of response,,rs1800497,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,decreased likelihood of response,,rs1800497,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,decreased response,,rs1801133,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,increased likelihood of response,,rs2283265,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,decreased response,,rs28363170,FALSE
CHEMBL964,ALDH2,"ATXN2, BRAP, MAPKAPK5-AS1, SH2B3","LVMVR, LVEDV, LVEDV_BSA, LVESV, LVESV_BSA, LVSV_BSA, LVSV, LVMVR, LVSV, LVSV_BSA, LVEDV, LVESV_BSA, LVEDV_BSA, LVESV, RVEDV_BSA, RVEDV, RVSV, RVESV_BSA, RVSV_BSA, RVESV, RVEF, RVESV, RVSV, RVEDV, RVEDV_BSA, RVSV_BSA, RVESV_BSA","",United States,DISULFIRAM,No,INHIBITOR,Aldehyde dehydrogenase inhibitor,"['COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'cocaine dependence', 'Cocaine dependence unspecified (disorder)', 'Cocaine addiction', 'cocaine addiction', 'Cocaine dependence (disorder)', 'Cocaine dependence unspecified use', 'Mental and behavioral disorder due to use of cocaine: dependence syndrome (disorder)', 'Cocaine drug dependence NOS (disorder)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'parasitic infection', 'parasitic skin disorder', 'parasitic liver disorder', 'Parasitic eye infection (disorder)', 'parasitic animal', 'psorospermiasis', 'Parasitism', 'intestinal parasitism unspecified (disorder)', 'intestinal parasitism unspecified', 'skin Infestation NOS', 'Ectoparasitic disease', 'Disease caused by parasite', 'Parasitic infectious disease of the central nervous system (disorder)', 'parasitic eye infectious disease', 'Diseases Parasitic', 'parasitic lung infectious disease', 'Parasitic disease', 'Parasite infestation NOS', 'parasitic pregnancy complication', 'parasitic infestation of orbit', 'intestinal parasitism NOS (disorder)', 'animal parasitic infectious disease', 'parasitic intestinal infectious disease', 'parasitic skin infectious disease', 'Parasitic infestation of orbit (disorder)', 'Disease caused by parasite (disorder)', 'Parasitism NOS', 'parasitic gastrointestinal disorder', 'Parasitic infection NOS', 'Parasitosis', 'Infestation NOS', 'intestinal parasitism (disorder)', 'Parasitic skin infestation (disorder)', 'central nervous system parasitic infectious disease', 'Psorospermiasis (disorder)', 'parasitic endophthalmitis', 'parasitic infectious disease', 'Parasitic infection of skin', 'Parasitic disease NOS', 'parasitic liver infectious disease', 'Parasite infestation', 'Parasitic endophthalmitis NOS (disorder)', 'Parasitic Diseases', 'parasitic disease', 'disease caused by parasite', 'Parasitic endophthalmitis (disorder)', 'parasitic eye infection', 'Infestation', 'Disease caused by parasite NOS', 'Parasitic endophthalmitis NOS', 'PARASITIC DIS', 'Parasitosis NOS', 'Parasitic infectious disease NOS', 'Disease Parasitic', 'Parasitic infection of lung', 'parasitemia', 'ectoparasitic disease', 'parasitism', 'diseases parasitic', 'disease parasitic', 'parasitosis', 'parasite infestation', 'infestation', 'Fatigue', 'Tired', 'Tiredness', 'germ cell tumor', 'tumor of germ cell', 'tumour of germ cell', 'tumor of the germ cell', 'tumour of the germ cell', 'neoplasm of germ cell', 'neoplasm of the germ cell', 'germ cell neoplasm', 'germ cells tumors', 'germ cells tumours', 'germ cell tumour', 'germ cell cancer', 'malignant tumour of the germ cell', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'methamphetamine dependence', 'metamphetamine addiction', 'Amphetamine-Related Disorders', 'metamphetamine dependence', 'HIV infection', 'Human immunodeficiency virus infection', '[X]Unspecified human immunodeficiency virus [HIV] disease', 'Unspecified human immunodeficiency virus [HIV] disease (disorder)', 'HTLV III LAV Infections', 'HIV infectious disease', 'HTLV-III-LAV Infection', '[X]Unspecified human immunodeficiency virus [HIV] disease (disorder)', '[X]Human immunodeficiency virus disease (disorder)', '[X]Human immunodeficiency virus disease', 'Human immunodeficiency virus caused disease or disorder', 'HTLV III LAV INFECT', 'HTLV-III Infections', 'Infection HIV', 'HTLV WIII LAV INFECTIONS', 'T Lymphotropic Virus Type III Infections Human', 'Infections HTLV-III', 'T-Lymphotropic Virus Type III Infections Human', 'HUMAN IMMUNOdeficiency VIRUS [HIV] INFECTION', 'HTLV WIII INFECTIONS', 'LYMPHOTROPIC VIRUS TYPE III INFECTIONS HUMAN T', 'Human immunodeficiency virus disease (disorder)', 'HUMAN IMMUNO VIRUS DIS', 'HIV', 'HTLV III INFECT', 'Human immunodeficiency virus infection NOS', 'Human immunodeficiency virus disease or disorder', 'HIV Infection', 'Human immunodeficiency virus [HIV] disease', 'Human immunodeficiency virus infectious disease', 'Human immunodeficiency virus disease', 'Infections HTLV-III-LAV', 'Infections HIV', 'Infection HTLV-III', 'HTLV-III-LAV Infections', 'HTLV III Infections', 'human immunodeficiency virus', 'HTLV-III Infection', 'HIV - Human immunodeficiency virus infection', 'HIV INFECT', 'T LYMPHOTROPIC VIRUS TYPE III INFECT HUMAN', 'Human immunodeficiency virus infection (disorder)', 'HIV Infections', 'Infection HTLV-III-LAV', 'human immunodeficiency virus infectious disease', 'inherited retinal dystrophy', 'fundus dystrophy', 'hereditary retinal dystrophy', 'hereditary retinal degeneration', 'familial retinal dystrophy', 'genetic retinal dystrophy', 'retinal dystrophy', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'metastatic melanoma', 'metastatic malignant melanoma', 'Aldehyde dehydrogenase mitochondrial', 'ALDH2', 'ALDM', 'ALDH class 2', 'ALDH-E2', 'ALDHI', 'aldehyde dehydrogenase mitochondrial', 'acetaldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family (mitochondrial)', 'epididymis secretory sperm binding protein', 'liver mitochondrial ALDH', 'nucleus-encoded mitochondrial aldehyde dehydrogenase 2', 'aldehyde dehydrogenase 2 family member', 'infectious disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'phenotype', 'respiratory or thoracic disease', 'genetic familial or congenital disease', 'disorder of visual system', 'nutritional or metabolic disease', 'hematologic disease', 'immune system disease', 'integumentary system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1951 and is indicated for parasitic infection and alcohol dependence and has 19 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0001067', 'MONDO_0007079']",pharmgkb,efficacy,increased response,,rs678849,FALSE
CHEMBL1174,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",EPTIFIBATIDE,Yes,INHIBITOR,Integrin alpha-IIb/beta-3 inhibitor,"['cardiovascular disease', 'Unspecified circulatory system disorder', 'Cardiovascular Diseases', 'Other forms of heart disease', 'Diseases Cardiovascular', 'Other heart disease (disorder)', 'Other pericardial disease NOS', 'Disease of cardiovascular system (disorder)', 'Cardiovascular Disorders', 'Other ill-defined heart diseases', 'ASCVD', 'Other heart disease NOS (disorder)', 'Other forms of heart disease (disorder)', 'Disorder of the circulatory system', 'cardiovascular disorder', 'Certain sequelae of myocardial infarction not elsewhere classified', 'PERICARDIAL DISEASE NEC', 'DISEASES OF THE CIRCULATORY SYSTEM', 'Other heart disease', 'Ill-defined descriptions and complications of heart disease', 'cardiovascular system disease', 'Cardiovascular disorder NOS', '[X]Other specified diseases of pericardium', '[X]Cardiovascular disease unspecified', 'Other ill-defined heart disease (disorder)', 'disease or disorder of cardiovascular system', 'Cardiovascular system disease', 'Circulatory system disease NOS', 'ILL-DEFINED HRT DIS NEC', '[X]Other specified diseases of pericardium (disorder)', 'Other ill-defined heart disease NOS (disorder)', 'circulatory system disease', 'cardiovascular disease (CVD)', '[X]Other ill-defined heart diseases (disorder)', 'Other pericardial disease NOS (disorder)', 'CARDIOVASC DIS', 'Other specified diseases of pericardium', 'PAPILLARY MUSCLE DIS NEC', 'Cardiovascular disease unspecified', 'OTHER SEQUELAE OF MI NEC', 'Other ill-defined heart disease NOS', 'Disease of cardiovascular system', '[X]Other forms of heart disease', 'Other specified pericardial disease NOS', 'Other diseases of pericardium (disorder)', 'Disorder of cardiovascular system (disorder)', 'CVS disease', 'disorder of cardiovascular system', '[X]Other forms of heart disease (disorder)', 'Other disorders of papillary muscle', 'Disorder of cardiovascular system', 'Disease affecting entire cardiovascular system', 'cardiovascular system disease or disorder', 'Other heart disease NOS', 'Disease of cardiovascular system NOS', 'Other diseases of pericardium', 'Other diseases of endocardium (disorder)', 'disease of cardiovascular system', 'Other specified pericardial disease NOS (disorder)', 'CIRCULATORY DISEASE NOS', 'Disorder of circulatory system', 'Disease affecting entire cardiovascular system (disorder)', 'Disease Cardiovascular', 'Cardiovascular Disease (CVD)', 'Disorder of circulatory system NOS', 'CVD NOS', 'Other diseases of endocardium', '[X]Cardiovascular disease unspecified (disorder)', 'disease of subdivision of hemolymphoid system', '[X]Other ill-defined heart diseases', 'Other ill-defined heart disease', 'Other sequelae of myocardial infarction not elsewhere classified', 'Circulatory system disease NOS (disorder)', 'Cardiovascular Disorder', 'CVD', 'Cardiovascular disease NOS', 'Ischemic stroke', 'Ischaemic stroke', 'sickle cell anemia', 'sickle-cell/Hb-C disease without crisis', 'sickle cell disease', 'Hb-S/Hb-C disease', 'Hemoglobin S disease without crisis', 'Hb-SS disease without crisis', 'drepanocytosis', 'hemoglobin SC disease', 'sickling disorder due to Haemoglobin S', 'Haemoglobin S disease without crisis', 'haemoglobin SC disease', 'Hb SC disease', 'sickling disorder due to Hemoglobin S', 'HbS disease', 'Haemoglobin S disease', 'Hemoglobin S disease', 'acute coronary syndrome', 'syndromes acute coronary', 'coronary syndromes acute', 'acute coronary syndromes', 'syndrome acute coronary', 'coronary syndrome acute', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'stroke', 'CVA (Cerebrovascular Accident)', 'Acute Cerebrovascular Accident', 'Cerebrovascular Apoplexya', 'Stroke NOS (disorder)', 'Brain Vascular Accident', 'Stroke and cerebrovascular accident unspecified (disorder)', 'CEREBROVASCULAR ACCIDENT (CVA)', 'Cerebrovascular Apoplexy', 'Stroke Cerebrovascular', 'ischemic stroke', 'Cerebrovascular Accidents', 'Acute Cerebrovascular Accidents', 'Vascular Accidents Brain', 'CVA', 'Brain Vascular Accidents', 'CVA CEREBROVASCULAR ACCIDENT', 'Apoplexy Cerebrovascular', 'Cerebral Stroke', 'Cerebral Strokes', 'CVAs (Cerebrovascular Accident)', 'cerebrovascular accident', 'CVA - Cerebrovascular accident', 'Cerebrovascular Stroke', 'Stroke/CVA - undefined', 'CVA cerebrovascular accident', 'undetermined stroke', 'Cerebrovascular Accident', 'stroke disorder', 'SYNDROME STROKE', 'Cerebrovascular Accident Acute', 'CVA - Cerebrovascular accident unspecified', 'Strokes', 'STROKE SYNDROME', 'Apoplexy', 'Cerebrovascular accident (disorder)', 'Strokes Cerebrovascular', 'Acute Strokes', 'Stroke and cerebrovascular accident unspecified', 'Vascular Accident Brain', 'Strokes Cerebral', 'Stroke NOS', 'Stroke Acute', 'syndrome stroke', 'Stroke Cerebral', 'Cerebrovascular Accidents Acute', 'cerebrovascular accident (CVA)', 'stroke syndrome', 'Cerebrovascular accident (disorder) [Ambiguous]', 'Strokes Acute', 'CVA (cerebral vascular accident)', 'Cerebrovascular Strokes', 'Acute Stroke', 'cerebral infarction', 'brain infarction', 'Venous Brain Infarction', 'POSTERIOR CIRC BRAIN INFARCT', 'Infarction Anterior Cerebral Circulation', 'Brain Infarctions Venous', 'Anterior Circulation Infarction Brain', 'INFARCT ANTERIOR CIRC BRAIN', 'Infarction Brain', 'Infarction Brain Posterior Circulation', 'Lacunar Infarctions', 'Brain Infarction Posterior Circulation', 'Posterior Circulation Infarction Brain', 'INFARCT ANTERIOR CEREBRAL CIRC', 'Infarction Anterior Circulation Brain', 'Brain Infarction Venous', 'Infarction Venous Brain', 'POSTERIOR CIRC INFARCT BRAIN', 'BRAIN INFARCT ANTERIOR CIRC', 'Anterior Circulation Brain Infarction', 'INFARCT POSTERIOR CIRC BRAIN', 'BRAIN INFARCT POSTERIOR CIRC', 'Brain Infarction Anterior Circulation', 'Lacunar Infarction', 'Venous Infarctions Brain', 'Infarction Brain Venous', 'Venous Brain Infarctions', 'INFARCT BRAIN POSTERIOR CIRC', 'ANTERIOR CIRC INFARCT BRAIN', 'Anterior Cerebral Circulation Infarction', 'Infarction Lacunar', 'Brain Venous Infarction', 'Brain Venous Infarctions', 'Infarctions Lacunar', 'Infarctions Brain', 'INFARCT BRAIN ANTERIOR CIRC', 'ANTERIOR CIRC BRAIN INFARCT', 'BRAIN INFARCT VENOUS', 'Infarction Posterior Circulation Brain', 'Venous Infarction Brain', 'ANTERIOR CEREBRAL CIRC INFARCT', 'Brain Infarctions', 'VENOUS INFARCT BRAIN', 'INFARCT LACUNAR', 'Infarction Brain Anterior Circulation', 'Infarctions Venous Brain', 'Infarctions Brain Venous', 'Posterior Circulation Brain Infarction', 'BRAIN INFARCT', 'Brain Infarction', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'ST Elevation Myocardial Infarction', 'ST Elevation Myocardial Infarction by ECG Finding', 'STEMI', 'ST Elevation Myocardial Infarction by EKG Finding', 'Recurrent thrombophlebitis', 'Recurrent phlebitis', 'Recurrent thrombosis', 'Non-ST Elevation Myocardial Infarction', 'Non-ST Elevation Myocardial Infarction by ECG Finding', 'NON-STEMI', 'Non-ST Elevation Myocardial Infarction by EKG Finding', 'NSTEMI', 'pneumonia', 'Pneumonia (disorder)', 'Pneumonitis (disorder)', 'acute pneumonia', 'Pneumonitis', 'Pneumonia (disorder) [Ambiguous]', 'Pneumonia due to other specified organism', 'Pneumonia NOS', 'pneumonia with infectious disease', 'chest infection due to pneumonia', 'Pneumonia NOS (disorder)', 'Pneumonia due to other specified organisms', 'Pneumonia due to other specified organisms (disorder)', 'septic shock', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-IIb', 'Integrin alpha-IIb heavy chain', 'Integrin alpha-IIb light chain form 1', 'Integrin alpha-IIb light chain form 2', 'ITGA2B', 'GP2B', 'ITGAB', 'CD41', 'GPIIb', 'CD41B', 'PPP1R93', 'GPalpha IIb', 'Platelet membrane glycoprotein IIb', 'protein phosphatase 1 regulatory subunit 93', 'platelet glycoprotein IIb of IIb/IIIa complex', 'GT1', 'GTA', 'HPA3', 'integrin alpha-IIb', 'alphaIIb protein', 'integrin alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex antigen CD41)', 'platelet fibrinogen receptor alpha subunit', 'platelet membrane glycoprotein IIb', 'platelet-specific antigen BAK', 'integrin subunit alpha 2b', 'phenotype', 'hematologic disease', 'genetic familial or congenital disease', 'nervous system disease', 'respiratory or thoracic disease', 'infectious disease']",protein complex,Protein drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1998 and is indicated for acute coronary syndrome and recurrent thrombophlebitis and has 11 investigational indications.,"['HP_0004419', 'EFO_0005672']","","","",,"",
CHEMBL1201584,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",ABCIXIMAB,Yes,INHIBITOR,Integrin alpha-IIb/beta-3 inhibitor,"['Shock', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'acute coronary syndrome', 'syndromes acute coronary', 'coronary syndromes acute', 'acute coronary syndromes', 'syndrome acute coronary', 'coronary syndrome acute', 'stroke', 'CVA (Cerebrovascular Accident)', 'Acute Cerebrovascular Accident', 'Cerebrovascular Apoplexya', 'Stroke NOS (disorder)', 'Brain Vascular Accident', 'Stroke and cerebrovascular accident unspecified (disorder)', 'CEREBROVASCULAR ACCIDENT (CVA)', 'Cerebrovascular Apoplexy', 'Stroke Cerebrovascular', 'ischemic stroke', 'Cerebrovascular Accidents', 'Acute Cerebrovascular Accidents', 'Vascular Accidents Brain', 'CVA', 'Brain Vascular Accidents', 'CVA CEREBROVASCULAR ACCIDENT', 'Apoplexy Cerebrovascular', 'Cerebral Stroke', 'Cerebral Strokes', 'CVAs (Cerebrovascular Accident)', 'cerebrovascular accident', 'CVA - Cerebrovascular accident', 'Cerebrovascular Stroke', 'Stroke/CVA - undefined', 'CVA cerebrovascular accident', 'undetermined stroke', 'Cerebrovascular Accident', 'stroke disorder', 'SYNDROME STROKE', 'Cerebrovascular Accident Acute', 'CVA - Cerebrovascular accident unspecified', 'Strokes', 'STROKE SYNDROME', 'Apoplexy', 'Cerebrovascular accident (disorder)', 'Strokes Cerebrovascular', 'Acute Strokes', 'Stroke and cerebrovascular accident unspecified', 'Vascular Accident Brain', 'Strokes Cerebral', 'Stroke NOS', 'Stroke Acute', 'syndrome stroke', 'Stroke Cerebral', 'Cerebrovascular Accidents Acute', 'cerebrovascular accident (CVA)', 'stroke syndrome', 'Cerebrovascular accident (disorder) [Ambiguous]', 'Strokes Acute', 'CVA (cerebral vascular accident)', 'Cerebrovascular Strokes', 'Acute Stroke', 'cerebral infarction', 'intermediate coronary syndrome', '(Angina: [crescendo] or [unstable] or [at rest]) or (preinfarction syndrome) or (impending infarction)', 'Worsening angina', 'Preinfarction angina (disorder)', 'angina at rest', 'Unstable angina', 'worsening angina', 'impending infarction', 'anginal chest pain at rest', 'Impending infarction (disorder)', 'Angina Unstable', 'Anginal chest pain at rest', 'Preinfarction angina', 'Angina at rest', 'unstable angina', 'ST Elevation Myocardial Infarction', 'ST Elevation Myocardial Infarction by ECG Finding', 'STEMI', 'ST Elevation Myocardial Infarction by EKG Finding', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'angina pectoris', 'Stenocardia', 'stable angina', 'angina', 'Angor Pectoris', 'Stenocardias', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'middle cerebral artery infarction', 'Infarction Middle Cerebral Artery', 'Recurrent thrombophlebitis', 'Recurrent phlebitis', 'Recurrent thrombosis', 'brain ischemia', 'ischaemic disease of brain', 'ischemic encephalopathy', 'ischaemic encephalopathy', 'brain ischaemic disease', 'ischemic disease of brain', 'brain ischemic disease', 'ischemia cerebrovascular', 'cerebrovascular ischemia', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'phenotype', 'cardiovascular disease', 'nervous system disease']",protein complex,Antibody drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1993 and is indicated for recurrent thrombophlebitis and intermediate coronary syndrome and has 7 investigational indications.,"['EFO_1000985', 'HP_0004419']","","","",,"",
CHEMBL1201584,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",ABCIXIMAB,Yes,INHIBITOR,Integrin alpha-V/beta-3 inhibitor,"['Shock', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'acute coronary syndrome', 'syndromes acute coronary', 'coronary syndromes acute', 'acute coronary syndromes', 'syndrome acute coronary', 'coronary syndrome acute', 'stroke', 'CVA (Cerebrovascular Accident)', 'Acute Cerebrovascular Accident', 'Cerebrovascular Apoplexya', 'Stroke NOS (disorder)', 'Brain Vascular Accident', 'Stroke and cerebrovascular accident unspecified (disorder)', 'CEREBROVASCULAR ACCIDENT (CVA)', 'Cerebrovascular Apoplexy', 'Stroke Cerebrovascular', 'ischemic stroke', 'Cerebrovascular Accidents', 'Acute Cerebrovascular Accidents', 'Vascular Accidents Brain', 'CVA', 'Brain Vascular Accidents', 'CVA CEREBROVASCULAR ACCIDENT', 'Apoplexy Cerebrovascular', 'Cerebral Stroke', 'Cerebral Strokes', 'CVAs (Cerebrovascular Accident)', 'cerebrovascular accident', 'CVA - Cerebrovascular accident', 'Cerebrovascular Stroke', 'Stroke/CVA - undefined', 'CVA cerebrovascular accident', 'undetermined stroke', 'Cerebrovascular Accident', 'stroke disorder', 'SYNDROME STROKE', 'Cerebrovascular Accident Acute', 'CVA - Cerebrovascular accident unspecified', 'Strokes', 'STROKE SYNDROME', 'Apoplexy', 'Cerebrovascular accident (disorder)', 'Strokes Cerebrovascular', 'Acute Strokes', 'Stroke and cerebrovascular accident unspecified', 'Vascular Accident Brain', 'Strokes Cerebral', 'Stroke NOS', 'Stroke Acute', 'syndrome stroke', 'Stroke Cerebral', 'Cerebrovascular Accidents Acute', 'cerebrovascular accident (CVA)', 'stroke syndrome', 'Cerebrovascular accident (disorder) [Ambiguous]', 'Strokes Acute', 'CVA (cerebral vascular accident)', 'Cerebrovascular Strokes', 'Acute Stroke', 'cerebral infarction', 'intermediate coronary syndrome', '(Angina: [crescendo] or [unstable] or [at rest]) or (preinfarction syndrome) or (impending infarction)', 'Worsening angina', 'Preinfarction angina (disorder)', 'angina at rest', 'Unstable angina', 'worsening angina', 'impending infarction', 'anginal chest pain at rest', 'Impending infarction (disorder)', 'Angina Unstable', 'Anginal chest pain at rest', 'Preinfarction angina', 'Angina at rest', 'unstable angina', 'ST Elevation Myocardial Infarction', 'ST Elevation Myocardial Infarction by ECG Finding', 'STEMI', 'ST Elevation Myocardial Infarction by EKG Finding', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'angina pectoris', 'Stenocardia', 'stable angina', 'angina', 'Angor Pectoris', 'Stenocardias', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'middle cerebral artery infarction', 'Infarction Middle Cerebral Artery', 'Recurrent thrombophlebitis', 'Recurrent phlebitis', 'Recurrent thrombosis', 'brain ischemia', 'ischaemic disease of brain', 'ischemic encephalopathy', 'ischaemic encephalopathy', 'brain ischaemic disease', 'ischemic disease of brain', 'brain ischemic disease', 'ischemia cerebrovascular', 'cerebrovascular ischemia', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'phenotype', 'cardiovascular disease', 'nervous system disease']",protein complex,Antibody drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1993 and is indicated for recurrent thrombophlebitis and intermediate coronary syndrome and has 7 investigational indications.,"['EFO_1000985', 'HP_0004419']","","","",,"",
CHEMBL1287935,CRHR1,"KANSL1, WNT3, MAPT, CRHR1, CDC27","LVMVR, LVMCF, LVMVR, LVM_BSA, LVMCF, LVM, RVSV, RVEDV_BSA","","",VERUCERFONT,No,ANTAGONIST,Corticotropin releasing factor receptor 1 antagonist,"['post-traumatic stress disorder', 'traumatic neurosis', 'PTSD - Post-traumatic stress disorder', 'disorder post-traumatic stress', 'Posttraumatic Neuroses', 'Post-traumatic stress syndrome', 'POST TRAUMATIC STRESS DIS', 'Delayed Onset Post-Traumatic Stress Disorder', 'Delayed Onset Post Traumatic Stress Disorder', 'Post-Traumatic Neurosis', 'Posttraumatic stress disorder', 'Neuroses Posttraumatic', 'Post-Traumatic Neuroses', 'Post Traumatic Stress Disorders', 'POSTTRAUMATIC STRESS DIS', 'Stress Disorders Post Traumatic', 'Neuroses Post-Traumatic', 'Stress Disorder Post Traumatic', 'CHRONIC POST TRAUMATIC STRESS DIS', 'Posttraumatic stress disorder NOS', 'Stress Disorder Post-Traumatic', 'Neuroses Post Traumatic', 'Acute Post Traumatic Stress Disorder', 'Chronic Post Traumatic Stress Disorder', 'STRESS DIS POSTTRAUMATIC', 'POSTTRAUMATIC STRESS DISORDERS', 'PTSD', 'post-traumatic stress disease', 'Stress Disorder Posttraumatic', 'Stress Disorders Post-Traumatic', 'ACUTE POST TRAUMATIC STRESS DIS', 'Acute Post-Traumatic Stress Disorder', 'STRESS DIS POST TRAUMATIC', 'Post-Traumatic Stress Disorders', 'DELAYED ONSET POST TRAUMATIC STRESS DIS', 'Chronic Post-Traumatic Stress Disorder', 'Stress Disorders Posttraumatic', 'Posttraumatic stress disorder (disorder)', 'combat neurosis', 'congenital adrenal hyperplasia', 'adrenal hyperplasia', 'adrenogenital syndrome', 'adrenogenital disorder', 'CAH', 'congenital adrenal gland hyperplasia', 'adrenal hyperplasia congenital', 'lipoid CAH', 'congenital lipoid adrenal hyperplasia', 'social anxiety disorder', 'social anxiety', 'social phobia', 'SAD', 'alcohol dependence', 'alcoholism', 'alcohol dependence protection against', 'aerodigestive tract cancer squamous cell alcohol-related protection against', 'alcohol dependence susceptibility to', 'major depressive disorder', 'MDD', 'irritable bowel syndrome', 'Mucous colitis', 'Syndromes Irritable Bowel', 'Psychogenic IBS', 'Syndrome Irritable Bowel', 'Nervous colitis', 'irritable colon', 'mucus colitis', 'Membranous colitis', 'Irritable bowel', 'Colitides Mucous', 'Irritable Colon', 'IC - Irritable colon', 'IBS', 'Adaptive colitis', 'Irritable colon (disorder)', 'Spastic colitis', 'IBD', 'Spastic colon', 'Colon spasm', 'IBS - Irritable bowel syndrome', 'Irritable colon syndrome', 'Irritable Bowel Syndromes', 'spastic colon', 'Colitis Mucous', 'Colon Irritable', 'Irritable colon - Irritable bowel syndrome', '[X]Psychogenic IBS', 'Functional bowel disease', 'Mucous Colitides', 'Irritable bowel - IBS', 'psychogenic IBS', 'Corticotropin-releasing factor receptor 1', 'CRHR1', 'CRFR', 'CRFR1', 'CRHR', 'CRF-R-1', 'CRF-R1', 'CRFR-1', 'CRH-R-1', 'CRH-R1', 'CRF-R', 'CRF1', 'Corticotropin-releasing hormone receptor 1', 'corticotropin-releasing factor receptor', 'CRHR1L', 'corticotropin-releasing factor receptor 1', 'corticotropin-releasing factor type 1 receptor', 'seven transmembrane helix receptor', 'corticotropin releasing hormone receptor 1', 'psychiatric disorder', 'nervous system disease', 'genetic familial or congenital disease', 'endocrine system disease', 'nutritional or metabolic disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 6 investigational indications.,[],"","","",,"",
CHEMBL1743014,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",ETARACIZUMAB,No,ANTAGONIST,Integrin alpha-V/beta-3 antagonist,"['melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'metastatic melanoma', 'metastatic malignant melanoma', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'psoriasis', 'Psoriasis and similar disorders NOS (disorder)', 'Psoriasis and similar disorders (disorder)', 'Other and unspecified pityriasis', 'PUSTULOSIS OF PALMS SOLES', 'Pustulosis Palmaris et Plantaris', 'Psoriases', 'PSORIAS RELATED DIS NEC', 'Other psoriasis and similar disorders excluding psoriatic arthropathy', 'Pustular Psoriasis of Palms and Soles', 'Palmoplantaris Pustulosis', 'Psoriasis and similar disorders NOS', 'Psoriasis and similar disorders', 'Psoriasis and similar disorders (navigational concept)', 'PUSTULAR PSORIASIS OF PALMS SOLES', 'Pustulosis of Palms and Soles', 'Other psoriasis and similar disorders (disorder)', 'OTHER PSORIASIS', 'Other psoriasis and similar disorders', 'PITYRIASIS NEC & NOS', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'rheumatoid arthritis', 'atrophic arthritis', 'Arthritis Rheumatoid', 'Rheumatoid arthritis NOS', 'rheumatoid arthritis progression of', 'Rheumatic gout', 'RA', 'Arthritis or polyarthritis rheumatic', 'Rheumatoid arthritis NOS (disorder)', 'Chronic rheumatic arthritis', 'Proliferative arthritis', 'Rheumatoid disease', 'RA - Rheumatoid arthritis', 'Rheumatoid arthritis (disorder)', 'RhA - Rheumatoid arthritis', 'arthritis rheumatoid', 'autoimmune arthritis', 'arthritis or polyarthritis rheumatic', 'atrophic Arthritis', 'rheumatoid arthritis susceptibility to', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-V', 'Integrin alpha-V heavy chain', 'Integrin alpha-V light chain', 'ITGAV', 'MSK8', 'VNRA', 'CD51', 'Vitronectin receptor', 'Vitronectin receptor subunit alpha', 'VTNR', 'integrin alpha-V', 'antigen identified by monoclonal antibody L230', 'integrin alphaVbeta3', 'integrin alpha V (vitronectin receptor alpha polypeptide antigen CD51)', 'vitronectin receptor subunit alpha', 'integrin subunit alpha V', 'cancer or benign tumor', 'gastrointestinal disease', 'reproductive system or breast disease', 'genetic familial or congenital disease', 'immune system disease', 'integumentary system disease', 'urinary system disease', 'musculoskeletal or connective tissue disease']",protein complex,Antibody drug with a maximum clinical trial phase of II (across all indications) and has 8 investigational indications.,[],"","","",,"",
CHEMBL1743032,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",INTETUMUMAB,No,ANTAGONIST,Integrin alpha-V/beta-3 antagonist,"['prostate adenocarcinoma', 'adenocarcinoma of prostate', 'adenocarcinoma of the prostate', 'prostate gland adenocarcinoma', 'prad', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'Integrin alpha-V', 'Integrin alpha-V heavy chain', 'Integrin alpha-V light chain', 'ITGAV', 'MSK8', 'VNRA', 'CD51', 'Vitronectin receptor', 'Vitronectin receptor subunit alpha', 'VTNR', 'integrin alpha-V', 'antigen identified by monoclonal antibody L230', 'integrin alphaVbeta3', 'integrin alpha V (vitronectin receptor alpha polypeptide antigen CD51)', 'vitronectin receptor subunit alpha', 'integrin subunit alpha V', 'cancer or benign tumor', 'reproductive system or breast disease']",protein complex,Antibody drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL1743076,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",TADOCIZUMAB,No,ANTAGONIST,Integrin alpha-IIb/beta-3 antagonist,[],protein complex,Antibody drug with a maximum clinical trial phase of II.,"","","","",,"",
CHEMBL1800955,MYL4,"GOSR2, RPRML, CDC27, MYL4, WNT9B","LVEDV, LVSV_BSA, LVESV_BSA, LVSV, LVEDV_BSA, LVEDV, RVEDV, RVESV_BSA, RVEDV_BSA, RVESV, RVESV_BSA, RVEDV, RVESV, RVEF, RVEDV_BSA, RVSV, RVSV_BSA","","",OMECAMTIV MECARBIL,Yes,ACTIVATOR,Cardiac myosin activator,"['heart failure', 'Weak heart', 'Heart failure NOS', 'Heart failure unspecified', 'Heart: [weak] or [failure NOS]', 'Heart failure NOS (disorder)', 'cardiac failure', 'cardiac dysfunction', 'failure heart', 'Heart failure (disorder)', 'insufficiency Cardiac', 'cardiac insufficiency', 'Reduced left ventricular ejection fraction', 'Reduced ejection fraction', 'Myosin-6', 'MYH6', 'MYHCA', 'MyHC-alpha', 'Myosin heavy chain 6', 'Myosin heavy chain cardiac muscle alpha isoform', 'cardiomyopathy hypertrophic 1', 'ASD3', 'CMD1EE', 'CMH14', 'MYHC', 'SSS3', 'alpha-MHC', 'myosin-6', 'myHC-alpha', 'myosin heavy polypeptide 6 cardiac muscle alpha (cardiomyopathy hypertrophic 1)', 'myosin heavy chain 6', 'Myosin light chain 3', 'MYL3', 'CMLC1', 'MLC1SB', 'VLCl', 'MLC-lV/sb', 'CMH8', 'VLC1', 'MLC1V', 'Cardiac myosin light chain 1', 'Myosin light chain 1 slow-twitch muscle B/ventricular isoform', 'Ventricular myosin alkali light chain', 'Ventricular myosin light chain 1', 'Ventricular/slow twitch myosin alkali light chain', 'myosin light chain 3', 'cardiac myosin light chain 1', 'myosin light chain 3 alkali; ventricular skeletal slow', 'myosin light polypeptide 3 alkali; ventricular skeletal slow', 'ventricular myosin alkali light chain', 'ventricular myosin light chain 1', 'ventricular/slow twitch myosin alkali light chain', 'Myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'MYL2', 'MLC2', 'MLC-2', 'MLC-2v', 'MLC-2s/v', 'CMH10', 'Cardiac myosin light chain 2', 'Myosin light chain 2 slow skeletal/ventricular muscle isoform', 'Ventricular myosin light chain 2', 'cardiac ventricular myosin light chain 2', 'MFM12', 'myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'RLC of myosin', 'S15D myosin regulatory light chain 2', 'T160D myosin regulatory light chain 2', 'cardiac myosin light chain 2', 'myosin light chain 2 regulatory cardiac slow', 'myosin light polypeptide 2 regulatory cardiac slow', 'regulatory light chain of myosin', 'slow cardiac myosin regulatory light chain 2', 'ventricular myosin light chain 2', 'myosin light chain 2', 'Myosin regulatory light chain 2 atrial isoform', 'MYL7', 'MYL2A', 'MYLC2A', 'MLC-2a', 'MLC2a', 'Myosin light chain 2a', 'Myosin regulatory light chain 7', 'myosin regulatory light chain 2 atrial isoform', 'myosin light chain 2a', 'myosin regulatory light chain 7', 'myosin light chain 7 regulatory', 'myosin light polypeptide 7 regulatory', 'myosin light chain 7', 'Myosin-7B', 'MYH7B', 'KIAA1512', 'dJ756N5.1', 'MYH14', 'MHC14', 'lncMYH7b', 'Antigen MLAA-21', 'Myosin cardiac muscle beta chain', 'Myosin heavy chain 7B cardiac muscle beta isoform', 'Slow A MYH14', 'myosin-7B', 'U937-associated antigen', 'antigen MLAA-21', 'myosin heavy chain 7B cardiac muscle beta', 'myosin heavy polypeptide 7B cardiac muscle beta', 'slow A MYH14', 'myosin heavy chain 7B', 'Myosin-7', 'MYH7', 'MYHCB', 'MyHC-slow', 'MyHC-beta', 'CMD1S', 'Myosin heavy chain 7', 'Myosin heavy chain slow isoform', 'Myosin heavy chain cardiac muscle beta isoform', 'CMH1', 'CMYP7A', 'CMYP7B', 'MPD1', 'SPMD', 'SPMM', 'myosin-7', 'cardiac muscle myosin heavy chain 7 beta', 'myHC-beta', 'myhc-slow', 'myosin 7', 'myosin heavy chain beta-subunit', 'myosin heavy chain 7 cardiac muscle beta', 'myosin heavy polypeptide 7 cardiac muscle beta', 'rhabdomyosarcoma antigen MU-RMS-40.7A', 'myosin heavy chain 7', 'Myosin light chain 4', 'MYL4', 'MLC1', 'PRO1957', 'ALC1', 'AMLC', 'GT1', 'Myosin light chain 1 embryonic muscle/atrial isoform', 'Myosin light chain alkali GT-1 isoform', 'myosin atrial/fetal muscle light chain', 'atrial myosin light chain 1', 'myosin light chain 4', 'myosin light chain 4 alkali; atrial embryonic', 'myosin light polypeptide 4 alkali; atrial embryonic', 'cardiovascular disease', 'phenotype']",protein complex,Small molecule drug with a maximum clinical trial phase of III and has 1 investigational indication.,[],"","","",,"",
CHEMBL1819077,CRHR1,"KANSL1, WNT3, MAPT, CRHR1, CDC27","LVMVR, LVMCF, LVMVR, LVM_BSA, LVMCF, LVM, RVSV, RVEDV_BSA","","",ONO-2333MS,No,ANTAGONIST,Corticotropin releasing factor receptor 1 antagonist,"['major depressive disorder', 'MDD', 'Corticotropin-releasing factor receptor 1', 'CRHR1', 'CRFR', 'CRFR1', 'CRHR', 'CRF-R-1', 'CRF-R1', 'CRFR-1', 'CRH-R-1', 'CRH-R1', 'CRF-R', 'CRF1', 'Corticotropin-releasing hormone receptor 1', 'corticotropin-releasing factor receptor', 'CRHR1L', 'corticotropin-releasing factor receptor 1', 'corticotropin-releasing factor type 1 receptor', 'seven transmembrane helix receptor', 'corticotropin releasing hormone receptor 1', 'psychiatric disorder', 'nervous system disease']",single protein,Small molecule drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL2103847,NPEPPS,"RPRML, GOSR2, CDC27, WNT9B, MYL4","LVEDV, LVEDV_BSA, LVSV_BSA, LVSV, LVEDV, LVESV_BSA, RVEDV, RVEDV_BSA, RVESV, RVESV_BSA, RVSV, RVEDV_BSA, RVSV_BSA, RVESV_BSA, RVEDV, RVEF, RVESV","","",TOSEDOSTAT,No,INHIBITOR,Aminopeptidase inhibitor,"['non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'myelodysplastic syndrome', 'MDS', 'myelodysplastic neoplasm', 'MDS unclassifiable', 'myelodysplastic syndrome somatic', 'myelodysplasia', 'oligoblastic leukaemia', 'myelodysplastic syndromes', 'MDS-U', 'dysmyelopoietic syndrome', 'oligoblastic leukemia', 'preleukemia', 'myelodysplastic syndrome/neoplasm', 'hematopoeitic - myelodysplastic syndrome (MDS)', 'smouldering leukaemia', 'myelodysplastic syndrome unclassifiable', 'smoldering leukemia', 'myelodysplastic syndrome susceptibility to', 'Cytosol aminopeptidase', 'LAP3', 'LAPEP', 'PEPS', 'LAP-3', 'LAP', 'Cysteinylglycine-S-conjugate dipeptidase', 'Leucine aminopeptidase 3', 'Leucyl aminopeptidase', 'Peptidase S', 'Proline aminopeptidase', 'Prolyl aminopeptidase', 'HEL-S-106', 'cytosol aminopeptidase', 'cysteinylglycine-S-conjugate dipeptidase', 'epididymis secretory protein Li 106', 'leucyl aminopeptidase', 'peptidase S', 'proline aminopeptidase', 'prolyl aminopeptidase', 'leucine aminopeptidase 3', 'Aminopeptidase Q', 'LVRN', 'AQPEP', 'AP-Q', 'APQ', 'FLJ90650', 'TAQPEP', 'CHL2 antigen', 'Laeverin', 'aminopeptidase Q', 'laeverin', 'Xaa-Pro aminopeptidase 3', 'XPNPEP3', 'X-Pro aminopeptidase 3', 'APP3', 'NPHPL1', 'ICP55', 'Aminopeptidase P3', 'Intermediate Cleaving Peptidase 55', 'xaa-Pro aminopeptidase 3', 'X-prolyl aminopeptidase 3 mitochondrial', 'probable Xaa-Pro aminopeptidase 3', 'X-prolyl aminopeptidase 3', 'Endoplasmic reticulum aminopeptidase 1', 'ERAP1', 'APPILS', 'ARTS1', 'KIAA0525', 'UNQ584/PRO1154', 'A-LAP', 'PILS-AP', 'ARTS-1', 'ERAAP1', 'Adipocyte-derived leucine aminopeptidase', 'Aminopeptidase PILS', 'Puromycin-insensitive leucyl-specific aminopeptidase', 'Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator', 'aminopeptidase regulator of TNFR1 shedding', 'adipocyte-derived leucine aminopeptidase', 'puromycin-insensitive leucyl-specific aminopeptidase', 'ALAP', 'ERAAP', 'PILSAP', 'endoplasmic reticulum aminopeptidase 1', 'aminopeptidase PILS', 'endoplasmic reticulum aminopeptidase associated with antigen processing', 'type 1 tumor necrosis factor receptor shedding aminopeptidase regulator', 'Probable aminopeptidase NPEPL1', 'NPEPL1', 'KIAA1974', 'FLJ11583', 'bA261P9.2', 'Aminopeptidase-like 1', 'probable aminopeptidase NPEPL1', 'uncharacterized protein LOC124904942', 'LOC124904942', 'aminopeptidase like 1', 'Aminopeptidase B', 'RNPEP', 'APB', 'AP-B', 'Arginine aminopeptidase', 'Arginyl aminopeptidase', 'aminopeptidase B', 'arginine aminopeptidase', 'arginyl aminopeptidase', 'Puromycin-sensitive aminopeptidase', 'NPEPPS', 'PSA', 'AAP-S', 'MP100', 'Cytosol alanyl aminopeptidase', 'puromycin-sensitive aminopeptidase', 'metalloproteinase MP100', 'cytosol alanyl aminopeptidase', 'aminopeptidase puromycin sensitive', 'Glutamyl aminopeptidase', 'ENPEP', 'CD249', 'EAP', 'AP-A', 'gp160', 'Aminopeptidase A', 'Differentiation antigen gp160', 'APA', 'glutamyl aminopeptidase', 'aminopeptidase A', 'differentiation antigen gp160', 'Methionine aminopeptidase 2', 'METAP2', 'MNPEP', 'P67EIF2', 'MAP 2', 'MetAP 2', 'p67', 'p67eIF2', 'MAP2', 'Initiation factor 2-associated 67 kDa glycoprotein', 'Peptidase M', 'methionine aminopeptidase 2', 'eIF-2-associated p67 homolog', 'initiation factor 2-associated 67 kDa glycoprotein', 'peptidase M 2', 'testicular tissue protein Li 17', 'methionyl aminopeptidase 2', 'Endoplasmic reticulum aminopeptidase 2', 'ERAP2', 'LRAP', 'L-RAP', 'Leukocyte-derived arginine aminopeptidase', 'leukocyte-derived arginine aminopeptidase', 'endoplasmic reticulum aminopeptidase 2', 'Aminopeptidase N', 'ANPEP', 'APN', 'CD13', 'PEPN', 'AP-N', 'hAPN', 'AP-M', 'LAP1', 'gp150', 'p150', 'Alanyl aminopeptidase', 'Aminopeptidase M', 'Microsomal aminopeptidase', 'Myeloid plasma membrane glycoprotein CD13', 'aminopeptidase N', 'aminopeptidase M', 'microsomal aminopeptidase', 'membrane alanyl aminopeptidase', 'GP150', 'P150', 'alanyl (membrane) aminopeptidase', 'myeloid plasma membrane glycoprotein CD13', 'alanyl aminopeptidase membrane', 'Aspartyl aminopeptidase', 'DNPEP', 'ASPEP', 'DAP', 'aspartyl aminopeptidase', 'Leucyl-cystinyl aminopeptidase', 'Leucyl-cystinyl aminopeptidase pregnancy serum form', 'LNPEP', 'OTASE', 'Cystinyl aminopeptidase', 'IRAP', 'OTase', 'P-LAP', 'CAP', 'PLAP', 'Insulin-regulated membrane aminopeptidase', 'Insulin-responsive aminopeptidase', 'Oxytocinase', 'Placental leucine aminopeptidase', 'cystinyl aminopeptidase', 'placental leucine aminopeptidase', 'leucyl-cystinyl aminopeptidase', 'AT (4) receptor', 'angiotensin IV receptor', 'insulin-regulated aminopeptidase', 'insulin-regulated membrane aminopeptidase', 'insulin-responsive aminopeptidase', 'otase', 'oxytocinase', 'vasopressinase', 'leucyl and cystinyl aminopeptidase', 'Aminopeptidase RNPEPL1', 'RNPEPL1 {ECO:0000303|PubMed:11017071', 'ECO:0000312|HGNC:HGNC:10079}', 'Arginyl aminopeptidase-like 1', 'Methionyl aminopeptidase', 'aminopeptidase B-like 1', 'aminopeptidase RNPEPL1', 'RNPEP-like 1', 'argininyl aminopeptidase-like 1', 'arginyl aminopeptidase (aminopeptidase B)-like 1', 'methionyl aminopeptidase', 'RNPEPL1', 'arginyl aminopeptidase like 1', 'Xaa-Pro aminopeptidase 1', 'XPNPEP1 {ECO:0000303|PubMed:10871044', 'ECO:0000312|HGNC:HGNC:12822}', 'XPNPEPL', 'XPNPEPL1', 'sAmp', 'Aminoacylproline aminopeptidase', 'Cytosolic aminopeptidase P', 'Soluble aminopeptidase P', 'X-Pro aminopeptidase 1', 'X-prolyl aminopeptidase 1 soluble', 'APP1', 'SAMP', 'XPNPEP', 'xaa-Pro aminopeptidase 1', 'X-prolyl aminopeptidase (aminopeptidase P) 1 soluble', 'aminoacylproline aminopeptidase', 'aminopeptidase P cytosolic', 'cytosolic aminopeptidase P', 'soluble aminopeptidase P', 'XPNPEP1', 'X-prolyl aminopeptidase 1', 'Methionine aminopeptidase 1D mitochondrial', 'METAP1D', 'MAP1D', 'MAP 1D', 'MetAP 1D', 'Metap1l', 'Methionyl aminopeptidase type 1D mitochondrial', 'Peptidase M 1D', 'methionine aminopeptidase 1D', 'methionine aminopeptidase 1D mitochondrial', 'CDS of metAP-3 within PCR fragment', 'metAP 1D', 'peptidase M 1D', 'methionyl aminopeptidase type 1D mitochondrial', 'Aminopeptidase O', 'AOPEP', 'C9orf3', 'ONPEP', 'AP-O', 'C90RF3', 'FLJ14675', 'APO', 'DYT31', 'aminopeptidase O', 'aminopeptidase O (putative)', 'Methionine aminopeptidase 1', 'METAP1', 'KIAA0094', 'MAP 1', 'MetAP 1', 'MetAP1A', 'MAP1A', 'Peptidase M 1', 'methionine aminopeptidase 1', 'metAP 1', 'peptidase M 1', 'methionyl aminopeptidase 1', 'Xaa-Pro aminopeptidase 2', 'XPNPEP2', 'Membrane-bound APP', 'Membrane-bound AmP', 'mAmP', 'Membrane-bound aminopeptidase P', 'X-Pro aminopeptidase 2', 'AEACEI', 'APP2', 'xaa-Pro aminopeptidase 2', 'X-prolyl aminopeptidase (aminopeptidase P) 2 membrane-bound', 'membrane-bound APP', 'membrane-bound AmP', 'membrane-bound aminopeptidase P', 'X-prolyl aminopeptidase 2', 'respiratory or thoracic disease', 'cancer or benign tumor', 'hematologic disease', 'musculoskeletal or connective tissue disease', 'immune system disease', 'endocrine system disease', 'pancreas disease', 'gastrointestinal disease', 'genetic familial or congenital disease']",protein family,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 5 investigational indications.,[],"","","",,"",
CHEMBL2109621,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",ABITUZUMAB,No,INHIBITOR,Integrin alpha-V/beta-3 inhibitor,"['systemic scleroderma', 'Scleroderma', 'systemic sclerosis', 'SS - Systemic sclerosis', 'systemic Scleroderma', 'PSS (progressive systemic sclerosis)', 'Scleroderma Systemic', 'Sclerosis Systemic', 'Systemic sclerosis', 'Progressive systemic sclerosis', 'Thibierge-Weissenbach syndrome', 'Scleroderma diffuse', 'SSc diffuse sclerosis', 'Scleroderma syndrome', 'Scleroderma (& [systemic sclerosis])', 'Scleroderma systemic', 'PSS - Progressive systemic sclerosis', 'progressive systemic sclerosis', 'SSc', 'diffuse sclerosis', 'Systemic sclerosis (disorder)', 'diffuse Scleroderma', 'interstitial lung disease', 'lung disease interstitial', 'ILD', 'lung diseases interstitial', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'metastatic colorectal cancer', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'Integrin alpha-V', 'Integrin alpha-V heavy chain', 'Integrin alpha-V light chain', 'ITGAV', 'MSK8', 'VNRA', 'CD51', 'Vitronectin receptor', 'Vitronectin receptor subunit alpha', 'VTNR', 'integrin alpha-V', 'antigen identified by monoclonal antibody L230', 'integrin alphaVbeta3', 'integrin alpha V (vitronectin receptor alpha polypeptide antigen CD51)', 'vitronectin receptor subunit alpha', 'integrin subunit alpha V', 'musculoskeletal or connective tissue disease', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'immune system disease', 'integumentary system disease', 'urinary system disease', 'disorder of visual system', 'cancer or benign tumor', 'gastrointestinal disease', 'reproductive system or breast disease', 'endocrine system disease']",protein complex,Antibody drug with a maximum clinical trial phase of II (across all indications) and has 5 investigational indications.,[],"","","",,"",
CHEMBL291657,CRHR1,"KANSL1, WNT3, MAPT, CRHR1, CDC27","LVMVR, LVMCF, LVMVR, LVM_BSA, LVMCF, LVM, RVSV, RVEDV_BSA","","",CRINECERFONT,No,ANTAGONIST,Corticotropin releasing factor receptor 1 antagonist,"['depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'congenital adrenal hyperplasia', 'adrenal hyperplasia', 'adrenogenital syndrome', 'adrenogenital disorder', 'CAH', 'congenital adrenal gland hyperplasia', 'adrenal hyperplasia congenital', 'lipoid CAH', 'congenital lipoid adrenal hyperplasia', 'Corticotropin-releasing factor receptor 1', 'CRHR1', 'CRFR', 'CRFR1', 'CRHR', 'CRF-R-1', 'CRF-R1', 'CRFR-1', 'CRH-R-1', 'CRH-R1', 'CRF-R', 'CRF1', 'Corticotropin-releasing hormone receptor 1', 'corticotropin-releasing factor receptor', 'CRHR1L', 'corticotropin-releasing factor receptor 1', 'corticotropin-releasing factor type 1 receptor', 'seven transmembrane helix receptor', 'corticotropin releasing hormone receptor 1', 'psychiatric disorder', 'nervous system disease', 'genetic familial or congenital disease', 'endocrine system disease', 'nutritional or metabolic disease']",single protein,Small molecule drug with a maximum clinical trial phase of III (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL3114577,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",ZALUNFIBAN,Yes,INHIBITOR,Integrin alpha-IIb/beta-3 inhibitor,"['ST Elevation Myocardial Infarction', 'ST Elevation Myocardial Infarction by ECG Finding', 'STEMI', 'ST Elevation Myocardial Infarction by EKG Finding', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-IIb', 'Integrin alpha-IIb heavy chain', 'Integrin alpha-IIb light chain form 1', 'Integrin alpha-IIb light chain form 2', 'ITGA2B', 'GP2B', 'ITGAB', 'CD41', 'GPIIb', 'CD41B', 'PPP1R93', 'GPalpha IIb', 'Platelet membrane glycoprotein IIb', 'protein phosphatase 1 regulatory subunit 93', 'platelet glycoprotein IIb of IIb/IIIa complex', 'GT1', 'GTA', 'HPA3', 'integrin alpha-IIb', 'alphaIIb protein', 'integrin alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex antigen CD41)', 'platelet fibrinogen receptor alpha subunit', 'platelet membrane glycoprotein IIb', 'platelet-specific antigen BAK', 'integrin subunit alpha 2b', 'cardiovascular disease']",protein complex,Small molecule drug with a maximum clinical trial phase of III (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL3189072,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",TIROFIBAN HYDROCHLORIDE,Yes,INHIBITOR,Integrin alpha-IIb/beta-3 inhibitor,"['myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-IIb', 'Integrin alpha-IIb heavy chain', 'Integrin alpha-IIb light chain form 1', 'Integrin alpha-IIb light chain form 2', 'ITGA2B', 'GP2B', 'ITGAB', 'CD41', 'GPIIb', 'CD41B', 'PPP1R93', 'GPalpha IIb', 'Platelet membrane glycoprotein IIb', 'protein phosphatase 1 regulatory subunit 93', 'platelet glycoprotein IIb of IIb/IIIa complex', 'GT1', 'GTA', 'HPA3', 'integrin alpha-IIb', 'alphaIIb protein', 'integrin alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex antigen CD41)', 'platelet fibrinogen receptor alpha subunit', 'platelet membrane glycoprotein IIb', 'platelet-specific antigen BAK', 'integrin subunit alpha 2b', 'cardiovascular disease']",protein complex,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1998 and is indicated for myocardial infarction.,['EFO_0000612'],"","","",,"",
CHEMBL3990042,MAPT,"WNT3, KANSL1, CRHR1, MAPT, CDC27","LVMCF, LVMVR, LVMCF, LVMVR, LVM, LVM_BSA, RVEDV_BSA, RVSV","","",GOSURANEMAB,No,INHIBITOR,Microtubule-associated protein tau inhibitor,"['Classical progressive supranuclear palsy', 'Steele-Richardson-Olszewski disease', 'Richardson syndrome', 'Classical PSP', 'Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'progressive supranuclear palsy', 'progressive supranuclear ophthalmoplegia', 'PSP syndrome', 'Steele-Richardson-Olszewski syndrome', 'familial progressive supranuclear palsy (type)', 'supranuclear palsy progressive', 'Microtubule-associated protein tau', 'MAPT', 'MAPTL', 'MTBT1', 'TAU', 'PHF-tau', 'tau', 'PPND', 'FTDP-17', 'MSTD', 'MTBT2', 'FLJ31424', 'MGC138549', 'PPP1R103', 'tau-40', 'Tau-PHF6', 'Neurofibrillary tangle protein', 'Paired helical filament-tau', 'G protein beta1/gamma2 subunit-interacting factor 1', 'microtubule-associated protein tau isoform 4', 'protein phosphatase 1 regulatory subunit 103', 'Tau-derived paired helical filament hexapeptide', 'DDPAC', 'microtubule-associated protein tau', 'neurofibrillary tangle protein', 'paired helical filament-tau', 'microtubule associated protein tau', 'genetic familial or congenital disease', 'psychiatric disorder', 'disorder of visual system', 'nervous system disease']",single protein,Antibody drug with a maximum clinical trial phase of II (across all indications) and has 3 investigational indications.,[],"","","",,"",
CHEMBL4297456,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",ATN-161,No,ANTAGONIST,Integrin alpha-V/beta-3 antagonist,"['Central Nervous System Neoplasm', 'tumour of central nervous system', 'tumour of CNS', 'tumor of central nervous system', 'CNS tumor', 'tumour of the CNS', 'tumour of the central nervous system', 'central nervous system neoplasm', 'neoplasm of central nervous system', 'brain/spinal cord tumour', 'tumor of the central nervous system', 'CNS tumour', 'central nervous system neoplasm (disease)', 'tumor of the CNS', 'CNS neoplasm', 'neoplasm of the central nervous system', 'neoplasm of CNS', 'tumor of CNS', 'central nervous system tumour', 'central nervous system tumor', 'brain/spinal cord tumor', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'Integrin beta-1', 'ITGB1', 'FNRB', 'MDF2', 'MSK12', 'CD29', 'GPIIA', 'Fibronectin receptor subunit beta', 'Glycoprotein IIa', 'VLA-4 subunit beta', 'VLA-BETA', 'VLAB', 'integrin beta-1', 'glycoprotein IIa', 'integrin VLA-4 beta subunit', 'integrin beta 1', 'integrin beta 1 (fibronectin receptor beta polypeptide antigen CD29 includes MDF2 MSK12)', 'very late activation protein beta polypeptide', 'integrin subunit beta 1', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-5', 'Integrin alpha-5 heavy chain', 'Integrin alpha-5 light chain', 'ITGA5', 'FNRA', 'CD49e', 'CD49 antigen-like family member E', 'Fibronectin receptor subunit alpha', 'Integrin alpha-F', 'VLA-5', 'fibronectin receptor alpha polypeptide', 'VLA5A', 'integrin alpha-5', 'ITGA5/SLC9B1 fusion', 'fibronectin receptor subunit alpha', 'fibronectin receptor alpha subunit', 'integrin alpha-F', 'integrin alpha 5 (fibronectin receptor alpha polypeptide)', 'very late activation protein 5 alpha subunit', 'integrin subunit alpha 5', 'Integrin alpha-V', 'Integrin alpha-V heavy chain', 'Integrin alpha-V light chain', 'ITGAV', 'MSK8', 'VNRA', 'CD51', 'Vitronectin receptor', 'Vitronectin receptor subunit alpha', 'VTNR', 'integrin alpha-V', 'antigen identified by monoclonal antibody L230', 'integrin alphaVbeta3', 'integrin alpha V (vitronectin receptor alpha polypeptide antigen CD51)', 'vitronectin receptor subunit alpha', 'integrin subunit alpha V', 'cancer or benign tumor', 'nervous system disease', 'urinary system disease']",protein complex,Protein drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL4297517,MYL4,"GOSR2, RPRML, CDC27, MYL4, WNT9B","LVEDV, LVSV_BSA, LVESV_BSA, LVSV, LVEDV_BSA, LVEDV, RVEDV, RVESV_BSA, RVEDV_BSA, RVESV, RVESV_BSA, RVEDV, RVESV, RVEF, RVEDV_BSA, RVSV, RVSV_BSA","",United States,MAVACAMTEN,Yes,INHIBITOR,Cardiac myosin inhibitor,"['hypertrophic cardiomyopathy', 'hypertrophic myocardiopathy', 'Cardiomyopathies Hypertrophic Obstructive', 'Hypertrophies Asymmetric Septal', 'Asymmetric Septal Hypertrophies', 'obstructive hypertrophic cardiomyopathy', 'Septal Hypertrophies Asymmetric', 'SUBVALV STENOSIS IDIOPATHIC HYPERTROPHIC', 'Hypertrophic Obstructive Cardiomyopathies', 'Cardiomyopathy hypertrophic', 'Asymmetric Septal Hypertrophy', 'hyper. obst. cardiomyopathy', 'primary hypertrophic cardiomyopathy (disorder) [Ambiguous]', 'hypertrophic obstructive cardiomyopathy', 'Septal Hypertrophy Asymmetric', 'Primary hypertrophic cardiomyopathy', 'Idiopathic Hypertrophic Subaortic Stenosis', 'Hypertrophy Asymmetric Septal', 'Hypertrophic Cardiomyopathies', 'hypertrophic subaortic stenosis', 'Obstructive cardiomyopathy', 'SUBVALV STENOSIS', 'IHSS', 'HCM - Hypertrophic cardiomyopathy', 'Hypertrophic cardiomyopathy (disorder)', 'Cardiomyopathies Hypertrophic', 'Cardiomyopathy Hypertrophic Obstructive', 'IHSSs', 'Hypertrophic Obstructive Cardiomyopathy', 'Subvalvular Stenosis Idiopathic Hypertrophic', 'Obstructive Cardiomyopathies Hypertrophic', 'Idiopathic Hypertrophic Subvalvular Stenosis', 'Hypertrophic obstructive cardiomyopathy (disorder)', 'HOCM - Hypertrophic obstructive cardiomyopathy', 'HYPERTR OBSTR CARDIOMYOP', 'Obstructive Cardiomyopathy Hypertrophic', 'HCM', 'IDIOPATHIC HYPERTROPHIC SUBVALV STENOSIS', 'familial hypertrophic cardiomyopathy', 'HCM - hypertrophic cardiomyopathy', 'heart failure', 'Weak heart', 'Heart failure NOS', 'Heart failure unspecified', 'Heart: [weak] or [failure NOS]', 'Heart failure NOS (disorder)', 'cardiac failure', 'cardiac dysfunction', 'failure heart', 'Heart failure (disorder)', 'insufficiency Cardiac', 'cardiac insufficiency', 'Myosin-6', 'MYH6', 'MYHCA', 'MyHC-alpha', 'Myosin heavy chain 6', 'Myosin heavy chain cardiac muscle alpha isoform', 'cardiomyopathy hypertrophic 1', 'ASD3', 'CMD1EE', 'CMH14', 'MYHC', 'SSS3', 'alpha-MHC', 'myosin-6', 'myHC-alpha', 'myosin heavy polypeptide 6 cardiac muscle alpha (cardiomyopathy hypertrophic 1)', 'myosin heavy chain 6', 'Myosin light chain 3', 'MYL3', 'CMLC1', 'MLC1SB', 'VLCl', 'MLC-lV/sb', 'CMH8', 'VLC1', 'MLC1V', 'Cardiac myosin light chain 1', 'Myosin light chain 1 slow-twitch muscle B/ventricular isoform', 'Ventricular myosin alkali light chain', 'Ventricular myosin light chain 1', 'Ventricular/slow twitch myosin alkali light chain', 'myosin light chain 3', 'cardiac myosin light chain 1', 'myosin light chain 3 alkali; ventricular skeletal slow', 'myosin light polypeptide 3 alkali; ventricular skeletal slow', 'ventricular myosin alkali light chain', 'ventricular myosin light chain 1', 'ventricular/slow twitch myosin alkali light chain', 'Myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'MYL2', 'MLC2', 'MLC-2', 'MLC-2v', 'MLC-2s/v', 'CMH10', 'Cardiac myosin light chain 2', 'Myosin light chain 2 slow skeletal/ventricular muscle isoform', 'Ventricular myosin light chain 2', 'cardiac ventricular myosin light chain 2', 'MFM12', 'myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'RLC of myosin', 'S15D myosin regulatory light chain 2', 'T160D myosin regulatory light chain 2', 'cardiac myosin light chain 2', 'myosin light chain 2 regulatory cardiac slow', 'myosin light polypeptide 2 regulatory cardiac slow', 'regulatory light chain of myosin', 'slow cardiac myosin regulatory light chain 2', 'ventricular myosin light chain 2', 'myosin light chain 2', 'Myosin regulatory light chain 2 atrial isoform', 'MYL7', 'MYL2A', 'MYLC2A', 'MLC-2a', 'MLC2a', 'Myosin light chain 2a', 'Myosin regulatory light chain 7', 'myosin regulatory light chain 2 atrial isoform', 'myosin light chain 2a', 'myosin regulatory light chain 7', 'myosin light chain 7 regulatory', 'myosin light polypeptide 7 regulatory', 'myosin light chain 7', 'Myosin-7B', 'MYH7B', 'KIAA1512', 'dJ756N5.1', 'MYH14', 'MHC14', 'lncMYH7b', 'Antigen MLAA-21', 'Myosin cardiac muscle beta chain', 'Myosin heavy chain 7B cardiac muscle beta isoform', 'Slow A MYH14', 'myosin-7B', 'U937-associated antigen', 'antigen MLAA-21', 'myosin heavy chain 7B cardiac muscle beta', 'myosin heavy polypeptide 7B cardiac muscle beta', 'slow A MYH14', 'myosin heavy chain 7B', 'Myosin-7', 'MYH7', 'MYHCB', 'MyHC-slow', 'MyHC-beta', 'CMD1S', 'Myosin heavy chain 7', 'Myosin heavy chain slow isoform', 'Myosin heavy chain cardiac muscle beta isoform', 'CMH1', 'CMYP7A', 'CMYP7B', 'MPD1', 'SPMD', 'SPMM', 'myosin-7', 'cardiac muscle myosin heavy chain 7 beta', 'myHC-beta', 'myhc-slow', 'myosin 7', 'myosin heavy chain beta-subunit', 'myosin heavy chain 7 cardiac muscle beta', 'myosin heavy polypeptide 7 cardiac muscle beta', 'rhabdomyosarcoma antigen MU-RMS-40.7A', 'myosin heavy chain 7', 'Myosin light chain 4', 'MYL4', 'MLC1', 'PRO1957', 'ALC1', 'AMLC', 'GT1', 'Myosin light chain 1 embryonic muscle/atrial isoform', 'Myosin light chain alkali GT-1 isoform', 'myosin atrial/fetal muscle light chain', 'atrial myosin light chain 1', 'myosin light chain 4', 'myosin light chain 4 alkali; atrial embryonic', 'myosin light polypeptide 4 alkali; atrial embryonic', 'musculoskeletal or connective tissue disease', 'cardiovascular disease']",protein complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2022 and is indicated for hypertrophic cardiomyopathy and has 1 investigational indication. This drug has a black box warning from the FDA.,['EFO_0000538'],"","","",,"",
CHEMBL4297860,MAPT,"WNT3, KANSL1, CRHR1, MAPT, CDC27","LVMCF, LVMVR, LVMCF, LVMVR, LVM, LVM_BSA, RVEDV_BSA, RVSV","","",TILAVONEMAB,No,INHIBITOR,Microtubule-associated protein tau inhibitor,"['progressive supranuclear palsy', 'progressive supranuclear ophthalmoplegia', 'PSP syndrome', 'Steele-Richardson-Olszewski syndrome', 'familial progressive supranuclear palsy (type)', 'supranuclear palsy progressive', 'Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'Microtubule-associated protein tau', 'MAPT', 'MAPTL', 'MTBT1', 'TAU', 'PHF-tau', 'tau', 'PPND', 'FTDP-17', 'MSTD', 'MTBT2', 'FLJ31424', 'MGC138549', 'PPP1R103', 'tau-40', 'Tau-PHF6', 'Neurofibrillary tangle protein', 'Paired helical filament-tau', 'G protein beta1/gamma2 subunit-interacting factor 1', 'microtubule-associated protein tau isoform 4', 'protein phosphatase 1 regulatory subunit 103', 'Tau-derived paired helical filament hexapeptide', 'DDPAC', 'microtubule-associated protein tau', 'neurofibrillary tangle protein', 'paired helical filament-tau', 'microtubule associated protein tau', 'disorder of visual system', 'nervous system disease', 'psychiatric disorder']",single protein,Antibody drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL4298021,MAPT,"WNT3, KANSL1, CRHR1, MAPT, CDC27","LVMCF, LVMVR, LVMCF, LVMVR, LVM, LVM_BSA, RVEDV_BSA, RVSV","","",ZAGOTENEMAB,No,INHIBITOR,Microtubule-associated protein tau inhibitor,"['Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'Microtubule-associated protein tau', 'MAPT', 'MAPTL', 'MTBT1', 'TAU', 'PHF-tau', 'tau', 'PPND', 'FTDP-17', 'MSTD', 'MTBT2', 'FLJ31424', 'MGC138549', 'PPP1R103', 'tau-40', 'Tau-PHF6', 'Neurofibrillary tangle protein', 'Paired helical filament-tau', 'G protein beta1/gamma2 subunit-interacting factor 1', 'microtubule-associated protein tau isoform 4', 'protein phosphatase 1 regulatory subunit 103', 'Tau-derived paired helical filament hexapeptide', 'DDPAC', 'microtubule-associated protein tau', 'neurofibrillary tangle protein', 'paired helical filament-tau', 'microtubule associated protein tau', 'psychiatric disorder', 'nervous system disease']",single protein,Antibody drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL4298093,MAPT,"WNT3, KANSL1, CRHR1, MAPT, CDC27","LVMCF, LVMVR, LVMCF, LVMVR, LVM, LVM_BSA, RVEDV_BSA, RVSV","","",SEMORINEMAB,No,INHIBITOR,Microtubule-associated protein tau inhibitor,"['Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'Microtubule-associated protein tau', 'MAPT', 'MAPTL', 'MTBT1', 'TAU', 'PHF-tau', 'tau', 'PPND', 'FTDP-17', 'MSTD', 'MTBT2', 'FLJ31424', 'MGC138549', 'PPP1R103', 'tau-40', 'Tau-PHF6', 'Neurofibrillary tangle protein', 'Paired helical filament-tau', 'G protein beta1/gamma2 subunit-interacting factor 1', 'microtubule-associated protein tau isoform 4', 'protein phosphatase 1 regulatory subunit 103', 'Tau-derived paired helical filament hexapeptide', 'DDPAC', 'microtubule-associated protein tau', 'neurofibrillary tangle protein', 'paired helical filament-tau', 'microtubule associated protein tau', 'psychiatric disorder', 'nervous system disease']",single protein,Antibody drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL429876,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",CILENGITIDE,No,ANTAGONIST,Integrin alpha-V/beta-3 antagonist,"['gliosarcoma', 'glioblastoma with a sarcomatous component', 'glioblastoma with sarcomatous component', 'sarcomatous glioblastoma', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'myelodysplastic syndrome', 'MDS', 'myelodysplastic neoplasm', 'MDS unclassifiable', 'myelodysplastic syndrome somatic', 'myelodysplasia', 'oligoblastic leukaemia', 'myelodysplastic syndromes', 'MDS-U', 'dysmyelopoietic syndrome', 'oligoblastic leukemia', 'preleukemia', 'myelodysplastic syndrome/neoplasm', 'hematopoeitic - myelodysplastic syndrome (MDS)', 'smouldering leukaemia', 'myelodysplastic syndrome unclassifiable', 'smoldering leukemia', 'myelodysplastic syndrome susceptibility to', 'chronic myeloproliferative disorder', 'MPN', 'chronic myeloproliferative disease', 'NCI CTEP SDC Chronic Myeloproliferative Disease Sub-Category Terminology', 'chronic myeloproliferative neoplasm', 'myeloproliferative tumor', 'myeloproliferative tumour', 'myeloproliferative neoplasm', 'CMPD', 'MPD', 'myeloproliferative disorder', 'myeloproliferative neoplasm chronic', 'CMPD U', 'chronic myeloproliferative disorders', 'myeloproliferative neoplasms', 'anaplastic astrocytoma', 'grade III astrocytoma', 'grade III astrocytic neoplasm', 'astrocytoma anaplastic malignant', 'malignant astrocytoma', 'grade III astrocytic tumor', 'grade III astrocytic tumour', 'anaplastic oligoastrocytoma', 'aMOA', 'WHO grade III mixed glioma', 'anaplastic mixed glioma', 'AOAST', 'Central Nervous System Neoplasm', 'tumour of central nervous system', 'tumour of CNS', 'tumor of central nervous system', 'CNS tumor', 'tumour of the CNS', 'tumour of the central nervous system', 'central nervous system neoplasm', 'neoplasm of central nervous system', 'brain/spinal cord tumour', 'tumor of the central nervous system', 'CNS tumour', 'central nervous system neoplasm (disease)', 'tumor of the CNS', 'CNS neoplasm', 'neoplasm of the central nervous system', 'neoplasm of CNS', 'tumor of CNS', 'central nervous system tumour', 'central nervous system tumor', 'brain/spinal cord tumor', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'cerebellar astrocytoma', 'cerebellum astrocytoma', 'cerebellum astrocytoma (excluding glioblastoma)', 'astrocytoma cerebellar', 'astrocytoma of the cerebellum', 'astrocytoma of cerebellum', 'astrocytoma (excluding glioblastoma) of cerebellum', 'central nervous system cancer', 'cancer of the CNS', 'malignant tumor of the central nervous system', 'malignant neoplasm of the CNS', 'CNS malignant neoplasms', 'cancer of CNS', 'malignant tumour of the central nervous system', 'cancer of the central nervous system', 'malignant tumor of central nervous system', 'malignant CNS tumor', 'malignant neoplasm of CNS', 'malignant central nervous system tumour', 'central nervous system neoplasms malignant', 'malignant tumour of CNS', 'malignant tumour of central nervous system', 'CNS cancer', 'malignant CNS neoplasms', 'malignant central nervous system neoplasm', 'CNS neoplasms malignant', 'malignant tumor of CNS', 'cancer of central nervous system', 'central nervous system tumours', 'malignant tumour of the CNS', 'malignant CNS tumour', 'malignant neoplasm of the central nervous system', 'malignant central nervous system tumor', 'malignant CNS neoplasm', 'central nervous system tumors', 'malignant tumor of the CNS', 'malignant neoplasm of central nervous system', 'male breast carcinoma', 'male breast cancer', 'carcinoma of male breast', 'carcinoma of the Male breast', 'neoplasm of male breast', 'malignant neoplasm of male breast', 'Male breast carcinoma', 'Male breast cancer', 'carcinoma of Male breast', 'breast cancer in men', 'breast cancer male', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'anaplastic oligodendroglioma', 'oligodendroglioma malignant', 'oligodendroglioma anaplastic malignant', 'malignant oligodendroglioma', 'WHO grade III oligodendroglial neoplasm', 'WHO grade III oligodendroglial tumor', 'WHO grade III oligodendroglial tumour', 'undifferentiated oligodendroglioma', 'diffuse intrinsic pontine glioma', 'DIPG', 'diffuse midline glioma', 'infiltrative brainstem glioma', 'leukemia', 'leukaemia (disease)', 'leukemias general', 'leukemias', 'leukemia (disease)', 'blood (leukemia)', 'leukemia disease', 'leukemia malignant', 'leukaemia NOS', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'kidney disease', 'renal system disease', 'Kidney Disorder', 'disease or disorder of kidney', 'renal disorder', 'disorder of kidney', 'renal disease', 'disease of kidney', 'nephropathy', 'kidney diseases', 'kidney disorder', 'kidney disease or disorder', 'squamous cell carcinoma', 'squamous cell carcinoma NOS (morphologic abnormality)', 'epidermoid cell cancer', 'epidermoid carcinoma', 'malignant epidermoid cell neoplasm', 'malignant epidermoid cell tumour', 'carcinoma squamous cell malignant', 'malignant squamous cell tumor', 'malignant epidermoid cell tumor', 'malignant squamous cell neoplasm', 'malignant squamous cell tumour', 'squamous cell cancer', 'squamous carcinoma', 'SCC', 'squamous cell epithelioma', 'squamous cell carcinoma (morphologic abnormality)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'small intestine cancer', 'malignant neoplasm of the small intestine', 'malignant neoplasm of small bowel', 'malignant small bowel tumour', 'malignant small intestinal neoplasm', 'malignant small intestine tumour', 'malignant neoplasm of the small bowel', 'malignant tumor of the small bowel', 'malignant neoplasm of small intestine', 'malignant small bowel tumor', 'malignant tumor of small bowel', 'malignant tumor of the small intestine', 'malignant tumour of small intestine', 'malignant tumour of the small bowel', 'malignant small bowel neoplasm', 'malignant tumor of small intestine', 'cancer of small intestine', 'malignant small intestine tumor', 'malignant tumour of the small intestine', 'malignant small intestine neoplasm', 'malignant tumour of small bowel', 'malignant neoplasms of the small intestine', 'small bowel tumors', 'small bowel tumours', 'cerebral astrocytoma', 'cerebral hemispheric astrocytoma', 'astrocytoma of the cerebrum', 'astrocytoma (excluding glioblastoma) of cerebral hemisphere', 'astrocytoma of cerebral hemispheres', 'astrocytoma of cerebrum', 'astrocytoma of the cerebral hemispheres', 'cerebral hemisphere astrocytoma (excluding glioblastoma)', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'Integrin beta-5', 'ITGB5', 'integrin beta-5', 'testis secretory sperm-binding protein Li 217p', 'integrin subunit beta 5', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-V', 'Integrin alpha-V heavy chain', 'Integrin alpha-V light chain', 'ITGAV', 'MSK8', 'VNRA', 'CD51', 'Vitronectin receptor', 'Vitronectin receptor subunit alpha', 'VTNR', 'integrin alpha-V', 'antigen identified by monoclonal antibody L230', 'integrin alphaVbeta3', 'integrin alpha V (vitronectin receptor alpha polypeptide antigen CD51)', 'vitronectin receptor subunit alpha', 'integrin subunit alpha V', 'cancer or benign tumor', 'nervous system disease', 'hematologic disease', 'genetic familial or congenital disease', 'immune system disease', 'musculoskeletal or connective tissue disease', 'integumentary system disease', 'reproductive system or breast disease', 'respiratory or thoracic disease', 'urinary system disease', 'gastrointestinal disease']",protein complex,Protein drug with a maximum clinical trial phase of III (across all indications) and has 20 investigational indications.,[],"","","",,"",
CHEMBL4594304,MYL4,"GOSR2, RPRML, CDC27, MYL4, WNT9B","LVEDV, LVSV_BSA, LVESV_BSA, LVSV, LVEDV_BSA, LVEDV, RVEDV, RVESV_BSA, RVEDV_BSA, RVESV, RVESV_BSA, RVEDV, RVESV, RVEF, RVEDV_BSA, RVSV, RVSV_BSA","","",DANICAMTIV,Yes,ACTIVATOR,Cardiac myosin activator,"['dilated cardiomyopathy', 'DCM - Dilated cardiomyopathy', 'Congestive cardiomyopathy', 'Idiopathic Cardiomyopathies Familial', 'Congestive Cardiomyopathies', 'Primary dilated cardiomyopathy', 'Cardiomyopathies Familial Idiopathic', 'Congestive dilated cardiomyopathy', 'Familial Idiopathic Cardiomyopathy', 'Cardiomyopathies Dilated', 'COCM - Congestive cardiomyopathy', 'Idiopathic Cardiomyopathy Familial', 'Cardiomyopathy Dilated with Conduction Deffect1', 'Cardiomyopathy Dilated CMD1A', 'Cardiomyopathies Congestive', 'Cardiomyopathy Dilated LMNA', 'primary dilated cardiomyopathy (disorder)', 'CCM - Congestive cardiomyopathy', 'Dilated Cardiomyopathies', 'Familial Idiopathic Cardiomyopathies', 'Cardiomyopathy Familial Idiopathic', 'DCM', 'Cardiomyopathy Dilated', 'Congestive cardiomyopathy (disorder)', 'Cardiomyopathy Congestive', 'familial dilated cardiomyopathy', 'primary dilated cardiomyopathy', 'congestive cardiomyopathy', 'idiopathic dilation cardiomyopathy', 'Myosin-6', 'MYH6', 'MYHCA', 'MyHC-alpha', 'Myosin heavy chain 6', 'Myosin heavy chain cardiac muscle alpha isoform', 'cardiomyopathy hypertrophic 1', 'ASD3', 'CMD1EE', 'CMH14', 'MYHC', 'SSS3', 'alpha-MHC', 'myosin-6', 'myHC-alpha', 'myosin heavy polypeptide 6 cardiac muscle alpha (cardiomyopathy hypertrophic 1)', 'myosin heavy chain 6', 'Myosin light chain 3', 'MYL3', 'CMLC1', 'MLC1SB', 'VLCl', 'MLC-lV/sb', 'CMH8', 'VLC1', 'MLC1V', 'Cardiac myosin light chain 1', 'Myosin light chain 1 slow-twitch muscle B/ventricular isoform', 'Ventricular myosin alkali light chain', 'Ventricular myosin light chain 1', 'Ventricular/slow twitch myosin alkali light chain', 'myosin light chain 3', 'cardiac myosin light chain 1', 'myosin light chain 3 alkali; ventricular skeletal slow', 'myosin light polypeptide 3 alkali; ventricular skeletal slow', 'ventricular myosin alkali light chain', 'ventricular myosin light chain 1', 'ventricular/slow twitch myosin alkali light chain', 'Myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'MYL2', 'MLC2', 'MLC-2', 'MLC-2v', 'MLC-2s/v', 'CMH10', 'Cardiac myosin light chain 2', 'Myosin light chain 2 slow skeletal/ventricular muscle isoform', 'Ventricular myosin light chain 2', 'cardiac ventricular myosin light chain 2', 'MFM12', 'myosin regulatory light chain 2 ventricular/cardiac muscle isoform', 'RLC of myosin', 'S15D myosin regulatory light chain 2', 'T160D myosin regulatory light chain 2', 'cardiac myosin light chain 2', 'myosin light chain 2 regulatory cardiac slow', 'myosin light polypeptide 2 regulatory cardiac slow', 'regulatory light chain of myosin', 'slow cardiac myosin regulatory light chain 2', 'ventricular myosin light chain 2', 'myosin light chain 2', 'Myosin regulatory light chain 2 atrial isoform', 'MYL7', 'MYL2A', 'MYLC2A', 'MLC-2a', 'MLC2a', 'Myosin light chain 2a', 'Myosin regulatory light chain 7', 'myosin regulatory light chain 2 atrial isoform', 'myosin light chain 2a', 'myosin regulatory light chain 7', 'myosin light chain 7 regulatory', 'myosin light polypeptide 7 regulatory', 'myosin light chain 7', 'Myosin-7B', 'MYH7B', 'KIAA1512', 'dJ756N5.1', 'MYH14', 'MHC14', 'lncMYH7b', 'Antigen MLAA-21', 'Myosin cardiac muscle beta chain', 'Myosin heavy chain 7B cardiac muscle beta isoform', 'Slow A MYH14', 'myosin-7B', 'U937-associated antigen', 'antigen MLAA-21', 'myosin heavy chain 7B cardiac muscle beta', 'myosin heavy polypeptide 7B cardiac muscle beta', 'slow A MYH14', 'myosin heavy chain 7B', 'Myosin-7', 'MYH7', 'MYHCB', 'MyHC-slow', 'MyHC-beta', 'CMD1S', 'Myosin heavy chain 7', 'Myosin heavy chain slow isoform', 'Myosin heavy chain cardiac muscle beta isoform', 'CMH1', 'CMYP7A', 'CMYP7B', 'MPD1', 'SPMD', 'SPMM', 'myosin-7', 'cardiac muscle myosin heavy chain 7 beta', 'myHC-beta', 'myhc-slow', 'myosin 7', 'myosin heavy chain beta-subunit', 'myosin heavy chain 7 cardiac muscle beta', 'myosin heavy polypeptide 7 cardiac muscle beta', 'rhabdomyosarcoma antigen MU-RMS-40.7A', 'myosin heavy chain 7', 'Myosin light chain 4', 'MYL4', 'MLC1', 'PRO1957', 'ALC1', 'AMLC', 'GT1', 'Myosin light chain 1 embryonic muscle/atrial isoform', 'Myosin light chain alkali GT-1 isoform', 'myosin atrial/fetal muscle light chain', 'atrial myosin light chain 1', 'myosin light chain 4', 'myosin light chain 4 alkali; atrial embryonic', 'myosin light polypeptide 4 alkali; atrial embryonic', 'musculoskeletal or connective tissue disease', 'cardiovascular disease']",protein complex,Small molecule drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL4594612,MAPT,"WNT3, KANSL1, CRHR1, MAPT, CDC27","LVMCF, LVMVR, LVMCF, LVMVR, LVM, LVM_BSA, RVEDV_BSA, RVSV","","",BEPRANEMAB,No,INHIBITOR,Microtubule-associated protein tau inhibitor,"['progressive supranuclear palsy', 'progressive supranuclear ophthalmoplegia', 'PSP syndrome', 'Steele-Richardson-Olszewski syndrome', 'familial progressive supranuclear palsy (type)', 'supranuclear palsy progressive', 'Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'Microtubule-associated protein tau', 'MAPT', 'MAPTL', 'MTBT1', 'TAU', 'PHF-tau', 'tau', 'PPND', 'FTDP-17', 'MSTD', 'MTBT2', 'FLJ31424', 'MGC138549', 'PPP1R103', 'tau-40', 'Tau-PHF6', 'Neurofibrillary tangle protein', 'Paired helical filament-tau', 'G protein beta1/gamma2 subunit-interacting factor 1', 'microtubule-associated protein tau isoform 4', 'protein phosphatase 1 regulatory subunit 103', 'Tau-derived paired helical filament hexapeptide', 'DDPAC', 'microtubule-associated protein tau', 'neurofibrillary tangle protein', 'paired helical filament-tau', 'microtubule associated protein tau', 'disorder of visual system', 'nervous system disease', 'psychiatric disorder']",single protein,Antibody drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL4650402,MAPT,"WNT3, KANSL1, CRHR1, MAPT, CDC27","LVMCF, LVMVR, LVMCF, LVMVR, LVM, LVM_BSA, RVEDV_BSA, RVSV","","",POSDINEMAB,No,INHIBITOR,Microtubule-associated protein tau inhibitor,"['Alzheimer disease', 'Alzheimers disease', 'Alzheimer dementia', """"""""Alzheimer's dementia"""""""", 'presenile and senile dementia', 'AD', """"""""Alzheimer's disease"""""""", 'Alzheimers dementia', 'Alzheimer disease familial', 'Microtubule-associated protein tau', 'MAPT', 'MAPTL', 'MTBT1', 'TAU', 'PHF-tau', 'tau', 'PPND', 'FTDP-17', 'MSTD', 'MTBT2', 'FLJ31424', 'MGC138549', 'PPP1R103', 'tau-40', 'Tau-PHF6', 'Neurofibrillary tangle protein', 'Paired helical filament-tau', 'G protein beta1/gamma2 subunit-interacting factor 1', 'microtubule-associated protein tau isoform 4', 'protein phosphatase 1 regulatory subunit 103', 'Tau-derived paired helical filament hexapeptide', 'DDPAC', 'microtubule-associated protein tau', 'neurofibrillary tangle protein', 'paired helical filament-tau', 'microtubule associated protein tau', 'psychiatric disorder', 'nervous system disease']",single protein,Antibody drug with a maximum clinical trial phase of II and has 1 investigational indication.,[],"","","",,"",
CHEMBL482950,CRHR1,"KANSL1, WNT3, MAPT, CRHR1, CDC27","LVMVR, LVMCF, LVMVR, LVM_BSA, LVMCF, LVM, RVSV, RVEDV_BSA","","",PEXACERFONT,No,ANTAGONIST,Corticotropin releasing factor receptor 1 antagonist,"['generalized anxiety disorder', 'GAD', 'generalized anxiety disorders', 'generalised anxiety disorder', 'generalised anxiety disorders', 'major depressive disorder', 'MDD', 'irritable bowel syndrome', 'Mucous colitis', 'Syndromes Irritable Bowel', 'Psychogenic IBS', 'Syndrome Irritable Bowel', 'Nervous colitis', 'irritable colon', 'mucus colitis', 'Membranous colitis', 'Irritable bowel', 'Colitides Mucous', 'Irritable Colon', 'IC - Irritable colon', 'IBS', 'Adaptive colitis', 'Irritable colon (disorder)', 'Spastic colitis', 'IBD', 'Spastic colon', 'Colon spasm', 'IBS - Irritable bowel syndrome', 'Irritable colon syndrome', 'Irritable Bowel Syndromes', 'spastic colon', 'Colitis Mucous', 'Colon Irritable', 'Irritable colon - Irritable bowel syndrome', '[X]Psychogenic IBS', 'Functional bowel disease', 'Mucous Colitides', 'Irritable bowel - IBS', 'psychogenic IBS', 'Corticotropin-releasing factor receptor 1', 'CRHR1', 'CRFR', 'CRFR1', 'CRHR', 'CRF-R-1', 'CRF-R1', 'CRFR-1', 'CRH-R-1', 'CRH-R1', 'CRF-R', 'CRF1', 'Corticotropin-releasing hormone receptor 1', 'corticotropin-releasing factor receptor', 'CRHR1L', 'corticotropin-releasing factor receptor 1', 'corticotropin-releasing factor type 1 receptor', 'seven transmembrane helix receptor', 'corticotropin releasing hormone receptor 1', 'psychiatric disorder', 'nervous system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of III (across all indications) and has 3 investigational indications.,[],"","","",,"",
CHEMBL514270,CRHR1,"KANSL1, WNT3, MAPT, CRHR1, CDC27","LVMVR, LVMCF, LVMVR, LVM_BSA, LVMCF, LVM, RVSV, RVEDV_BSA","","",EMICERFONT,No,ANTAGONIST,Corticotropin releasing factor receptor 1 antagonist,"['irritable bowel syndrome', 'Mucous colitis', 'Syndromes Irritable Bowel', 'Psychogenic IBS', 'Syndrome Irritable Bowel', 'Nervous colitis', 'irritable colon', 'mucus colitis', 'Membranous colitis', 'Irritable bowel', 'Colitides Mucous', 'Irritable Colon', 'IC - Irritable colon', 'IBS', 'Adaptive colitis', 'Irritable colon (disorder)', 'Spastic colitis', 'IBD', 'Spastic colon', 'Colon spasm', 'IBS - Irritable bowel syndrome', 'Irritable colon syndrome', 'Irritable Bowel Syndromes', 'spastic colon', 'Colitis Mucous', 'Colon Irritable', 'Irritable colon - Irritable bowel syndrome', '[X]Psychogenic IBS', 'Functional bowel disease', 'Mucous Colitides', 'Irritable bowel - IBS', 'psychogenic IBS', 'social anxiety disorder', 'social anxiety', 'social phobia', 'SAD', 'Corticotropin-releasing factor receptor 1', 'CRHR1', 'CRFR', 'CRFR1', 'CRHR', 'CRF-R-1', 'CRF-R1', 'CRFR-1', 'CRH-R-1', 'CRH-R1', 'CRF-R', 'CRF1', 'Corticotropin-releasing hormone receptor 1', 'corticotropin-releasing factor receptor', 'CRHR1L', 'corticotropin-releasing factor receptor 1', 'corticotropin-releasing factor type 1 receptor', 'seven transmembrane helix receptor', 'corticotropin releasing hormone receptor 1', 'gastrointestinal disease', 'psychiatric disorder', 'nervous system disease']",single protein,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL916,ITGB3,"RPRML, GOSR2, CDC27, WNT9B","LVEDV, LVEDV_BSA, LVESV_BSA, LVEDV, LVSV_BSA, LVSV, RVESV, RVEDV_BSA, RVESV_BSA, RVEDV, RVSV, RVEDV_BSA, RVSV_BSA, RVEF","","",TIROFIBAN,Yes,INHIBITOR,Integrin alpha-IIb/beta-3 inhibitor,"['brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Ischemic stroke', 'Ischaemic stroke', 'Non-ST Elevation Myocardial Infarction', 'Non-ST Elevation Myocardial Infarction by ECG Finding', 'NON-STEMI', 'Non-ST Elevation Myocardial Infarction by EKG Finding', 'NSTEMI', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'Renal insufficiency', 'Renal failure in adulthood', 'Renal failure', 'Recurrent thrombophlebitis', 'Recurrent phlebitis', 'Recurrent thrombosis', 'acute coronary syndrome', 'syndromes acute coronary', 'coronary syndromes acute', 'acute coronary syndromes', 'syndrome acute coronary', 'coronary syndrome acute', 'ST Elevation Myocardial Infarction', 'ST Elevation Myocardial Infarction by ECG Finding', 'STEMI', 'ST Elevation Myocardial Infarction by EKG Finding', 'stroke', 'CVA (Cerebrovascular Accident)', 'Acute Cerebrovascular Accident', 'Cerebrovascular Apoplexya', 'Stroke NOS (disorder)', 'Brain Vascular Accident', 'Stroke and cerebrovascular accident unspecified (disorder)', 'CEREBROVASCULAR ACCIDENT (CVA)', 'Cerebrovascular Apoplexy', 'Stroke Cerebrovascular', 'ischemic stroke', 'Cerebrovascular Accidents', 'Acute Cerebrovascular Accidents', 'Vascular Accidents Brain', 'CVA', 'Brain Vascular Accidents', 'CVA CEREBROVASCULAR ACCIDENT', 'Apoplexy Cerebrovascular', 'Cerebral Stroke', 'Cerebral Strokes', 'CVAs (Cerebrovascular Accident)', 'cerebrovascular accident', 'CVA - Cerebrovascular accident', 'Cerebrovascular Stroke', 'Stroke/CVA - undefined', 'CVA cerebrovascular accident', 'undetermined stroke', 'Cerebrovascular Accident', 'stroke disorder', 'SYNDROME STROKE', 'Cerebrovascular Accident Acute', 'CVA - Cerebrovascular accident unspecified', 'Strokes', 'STROKE SYNDROME', 'Apoplexy', 'Cerebrovascular accident (disorder)', 'Strokes Cerebrovascular', 'Acute Strokes', 'Stroke and cerebrovascular accident unspecified', 'Vascular Accident Brain', 'Strokes Cerebral', 'Stroke NOS', 'Stroke Acute', 'syndrome stroke', 'Stroke Cerebral', 'Cerebrovascular Accidents Acute', 'cerebrovascular accident (CVA)', 'stroke syndrome', 'Cerebrovascular accident (disorder) [Ambiguous]', 'Strokes Acute', 'CVA (cerebral vascular accident)', 'Cerebrovascular Strokes', 'Acute Stroke', 'cerebral infarction', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'viral pneumonia', 'Pneumonia Viral', 'Viruses caused pneumonia', 'Viruses pneumonia', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'venous thromboembolism', 'VTE', 'Integrin beta-3', 'ITGB3', 'GP3A', 'CD61', 'GPIIIa', 'Platelet membrane glycoprotein IIIa', 'platelet glycoprotein IIIa', 'antigen CD61', 'BDPLT16', 'BDPLT2', 'BDPLT24', 'GT', 'GT2', 'integrin beta-3', 'integrin beta 3', 'integrin beta chain beta 3', 'integrin beta 3 (platelet glycoprotein IIIa antigen CD61)', 'platelet membrane glycoprotein IIIa', 'integrin subunit beta 3', 'Integrin alpha-IIb', 'Integrin alpha-IIb heavy chain', 'Integrin alpha-IIb light chain form 1', 'Integrin alpha-IIb light chain form 2', 'ITGA2B', 'GP2B', 'ITGAB', 'CD41', 'GPIIb', 'CD41B', 'PPP1R93', 'GPalpha IIb', 'Platelet membrane glycoprotein IIb', 'protein phosphatase 1 regulatory subunit 93', 'platelet glycoprotein IIb of IIb/IIIa complex', 'GT1', 'GTA', 'HPA3', 'integrin alpha-IIb', 'alphaIIb protein', 'integrin alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex antigen CD41)', 'platelet fibrinogen receptor alpha subunit', 'platelet membrane glycoprotein IIb', 'platelet-specific antigen BAK', 'integrin subunit alpha 2b', 'cardiovascular disease', 'nervous system disease', 'phenotype', 'respiratory or thoracic disease', 'infectious disease']",protein complex,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1998 and is indicated for myocardial infarction and recurrent thrombophlebitis and has 11 investigational indications.,"['EFO_0000612', 'HP_0004419']","","","",,"",
CHEMBL1200485,RAF1,CAND2,LVEF,"","",SORAFENIB TOSYLATE,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'Ewing sarcoma/peripheral primitive neuroectodermal tumor', 'EFTs', """"""""tumors of the Ewing's family"""""""", """"""""Ewing's sarcoma/peripheral primitive neuroectodermal tumor"""""""", """"""""Ewing's sarcoma/peripheral primitive neuroectodermal tumour"""""""", 'Ewing family of tumours', """"""""Ewing's family of tumours"""""""", """"""""Ewing's family of tumors"""""""", 'Ewing sarcoma family of tumors', 'Ewing sarcoma family of tumours', """"""""tumours of the Ewing's family"""""""", 'Ewing family of tumors', """"""""tumours of Ewing's family"""""""", """"""""tumors of Ewing's family"""""""", 'Ewing sarcoma/peripheral PNET', 'male breast carcinoma', 'male breast cancer', 'carcinoma of male breast', 'carcinoma of the Male breast', 'neoplasm of male breast', 'malignant neoplasm of male breast', 'Male breast carcinoma', 'Male breast cancer', 'carcinoma of Male breast', 'breast cancer in men', 'breast cancer male', 'myeloid sarcoma', 'extramedullary myeloid tumor', 'granulocytic sarcoma', 'sarcoma myeloid malignant', 'chloroma', 'extramedullary myeloid tumour', 'MS', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'follicular thyroid carcinoma', 'follicular cancer of the thyroid gland', 'thyroid gland follicular cancer', 'follicular cancer of the thyroid', 'well-differentiated follicular carcinoma', 'follicular cancer of thyroid', 'follicular cancer of thyroid gland', 'thyroid gland follicular carcinoma', 'thyroid gland adenocarcinoma', 'follicular carcinoma of the thyroid gland', 'follicular carcinoma', 'thyroid follicular carcinoma', 'well-differentiated follicular adenocarcinoma', 'follicular thyroid gland carcinoma', 'follicular adenocarcinoma well differentiated (morphologic abnormality)', 'carcinoma follicular cell malignant', 'carcinoma of thyroid follicle', 'follicular adenocarcinoma (morphologic abnormality)', 'follicular adenocarcinoma', 'follicular carcinoma of thyroid gland', 'thyroid follicle carcinoma', 'follicular carcinoma of the thyroid', 'follicular thyroid cancer', 'follicular adenocarcinoma well differentiated', 'follicular carcinoma of thyroid', 'thyroid cancer', 'neoplasm of thyroid gland', 'thyroid gland neoplasm', 'thyroid gland cancer', 'malignant tumor of the thyroid gland', 'malignant neoplasm of the thyroid gland', 'malignant thyroid tumor', 'malignant thyroid neoplasm', 'malignant neoplasm of the thyroid', 'malignant tumor of the thyroid', 'malignant tumor of thyroid', 'malignant thyroid gland neoplasm', 'cancer of thyroid gland', 'malignant thyroid gland tumour', 'malignant thyroid tumour', 'malignant tumour of thyroid', 'malignant tumour of the thyroid gland', 'malignant thyroid gland tumor', 'malignant neoplasm of thyroid gland', 'malignant tumour of thyroid gland', 'malignant tumor of thyroid gland', 'malignant tumour of the thyroid', 'malignant neoplasm of thyroid', 'urinary bladder carcinoma', 'cancer of the urinary bladder', 'cancer of bladder', 'urinary bladder cancer', 'cancer of urinary bladder', 'bladder cancer', 'cancer of the bladder', 'carcinoma of the urinary bladder', 'bladder carcinoma', 'carcinoma bladder', 'carcinoma of urinary bladder', 'carcinoma of the bladder', 'carcinoma of bladder', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'salivary gland squamous cell carcinoma', 'salivary gland SCC', 'SCC of salivary gland', 'squamous cell carcinoma of salivary gland', 'SCC of the salivary gland', 'salivary gland epidermoid carcinoma', 'epidermoid carcinoma of the salivary gland', 'salivary gland squamous cell cancer', 'squamous cell carcinoma of the salivary gland', 'epidermoid carcinoma of salivary gland', 'saliva-secreting gland squamous cell carcinoma', 'squamous cell carcinoma of salivary glands', 'anaplastic oligodendroglioma', 'oligodendroglioma malignant', 'oligodendroglioma anaplastic malignant', 'malignant oligodendroglioma', 'WHO grade III oligodendroglial neoplasm', 'WHO grade III oligodendroglial tumor', 'WHO grade III oligodendroglial tumour', 'undifferentiated oligodendroglioma', 'thyroid carcinoma', 'cancer of thyroid', 'cancer of the thyroid', 'head and neck cancer thyroid', 'thyroid gland carcinoma', 'carcinoma of thyroid gland', 'carcinoma of thyroid', 'carcinoma of the thyroid', 'carcinoma of the thyroid gland', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'metastatic malignant neoplasm', 'malignant metastatic neoplasm', 'metastatic neoplasm malignant', 'metastatic cancer', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'gastrointestinal stromal tumor', 'gastrointestinal stromal tumor familial isolated cases', 'gastrointestinal stromal sarcoma', 'gant', 'stromal tumor of gastrointestinal tract', 'gastrointestinal stromal tumor isolated cases', 'stromal tumour of gastrointestinal tract', 'gist', 'gastrointestinal stromal tumour (gist)', 'gastrointestinal stromal neoplasm', 'gastrointestinal stromal tumor (gist)', 'gastrointestinal stromal tumors', 'gastrointestinal stromal tumours', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'lung neoplasm', 'mixed phenotype acute leukemia', 'MPAL', 'fallopian tube cancer', 'tumor of the fallopian tube', 'tumour of the fallopian tube', 'malignant tumour of the fallopian tube', 'malignant tumor of fallopian tubes', 'malignant tubal tumor', 'cancer of fallopian tubes', 'fallopian tube malignant neoplasm', 'tumor fallopian tube malignant', 'malignant tumour of fallopian tube', 'malignant fallopian tube neoplasm', 'fallopian tube malignant tumour', 'malignant tumor of fallopian tube', 'malignant tumor of the fallopian tube', 'malignant neoplasm of uterine tube', 'cancer of fallopian tube', 'malignant neoplasm of the fallopian tube', 'malignant tumour of fallopian tubes', 'neoplasm fallopian tube malignant', 'malignant neoplasm of fallopian tube', 'malignant fallopian tube tumor', 'tubal cancer', 'malignant fallopian tube tumour', 'fallopian tube malignant tumor', 'malignant tubal tumour', 'verrucous carcinoma', 'warty carcinoma', 'verrucous carcinoma NOS (morphologic abnormality)', 'verrucous squamous carcinoma', 'verrucous squamous cell carcinoma', 'verrucous epidermoid cell carcinoma', 'verrucous epidermoid carcinoma', 'renal pelvis/ureter urothelial carcinoma', 'renal pelvis and ureter transitional cell carcinoma', 'transitional cell cancer of the renal pelvis and ureter', 'renal pelvis and ureter urothelial carcinoma', 'TCC of the renal pelvis and ureter', 'TCC of renal pelvis and ureter', 'renal pelvis and ureter transitional cell cancer', 'renal pelvis and ureter TCC', 'transitional cell carcinoma of renal pelvis and ureter', 'transitional cell cancer of renal pelvis and ureter', 'urothelial carcinoma of the renal pelvis and ureter', 'soft tissue sarcoma', 'malignant soft tissue tumor', 'malignant soft tissue tumour', 'malignant mesenchymal tumor', 'sarcoma of the soft tissue', 'soft part sarcoma', 'sarcoma of soft tissue', 'malignant mesenchymal tumour', 'connective tissue sarcoma', 'non-Rhabdo. soft tissue sarcoma', 'grade III glioma', 'anaplastic glioma', 'WHO grade III glioma', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'nasal cavity and paranasal sinus squamous cell carcinoma', 'nasal cavity and paranasal sinus squamous cell cancer', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'hypopharyngeal carcinoma', 'cancer of the hypopharynx', 'cancer of hypopharynx', 'hypopharyngeal cancer', 'hypopharyngeal throat cancer', 'hypopharynx carcinoma', 'carcinoma of the hypopharynx', 'carcinoma of hypopharynx', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'chromophobe renal cell carcinoma', 'kidney chromophobe', 'chromophobe adenocarcinoma', 'chromophobe cell carcinoma of the kidney', 'chromophobe carcinoma', 'chromophobe renal cell adenocarcinoma', 'chromophobe cell carcinoma of kidney', 'renal cell carcinoma chromophobe cell', 'chromophobe renal cell cancer', 'chromophobe carcinoma of the kidney', 'chromophobe carcinoma of kidney', 'renal cell carcinoma chromophobe type', 'CHRCC', 'ChRCC', 'CRCC', 'therapy related acute myeloid leukemia and myelodysplastic syndrome', 'therapy-related AML and myelodysplastic syndrome', 'Secondary Acute myeloblastic Leukaemia', 'Secondary Acute granulocytic Leukemia', 'Secondary Acute granulocytic Leukaemia', 'Secondary AGL', 'secondary acute myeloid leukemia', 'secondary AML', 'Secondary Acute myeloid Leukemia (AML)', 'Secondary Acute myelocytic Leukaemia', 'Secondary Acute myelocytic Leukemia', 'Secondary Acute myeloid Leukaemia (AML)', 'secondary acute myeloid leukaemia', 'Secondary Acute myelogenous Leukemia', 'Secondary Acute myelogenous Leukaemia', 'Secondary Acute myeloblastic Leukemia', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'mucosal melanoma', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'laryngeal squamous cell carcinoma', 'squamous cell carcinoma of the larynx', 'laryngeal epidermoid carcinoma', 'squamous cell carcinoma of larynx', 'LSCC', 'larynx squamous cell carcinoma', 'epidermoid carcinoma of the larynx', 'larynx epidermoid carcinoma', 'epidermoid carcinoma of larynx', 'laryngeal throat squamous cell cancer', 'LXSC', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'Desmoid-type fibromatosis', 'desmoid tumor', 'desmoid fibromatosis', 'desmoid-type fibromatosis', 'deep fibromatosis/desmoid tumor', 'desmoid type fibromatosis', 'deep fibromatosis/desmoid tumour', 'deep fibromatosis', 'aggressive fibromatosis', 'familial infiltrative fibromatosis', 'desmoid disorder hereditary', 'fibromatosis familial infiltrative', 'FIF', 'desmoid disease hereditary', 'desmoid/aggressive fibromatosis', 'desmoid tumor caused by somatic mutation', 'acute promyelocytic leukemia', 'acute myeloblastic leukaemia 3', 'acute myeloblastic leukemia 3', 'acute myeloblastic leukaemia type 3', 'APL', 'acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants', 'AML with t(15;17)(q22;q12);(PML/RARalpha) and variants', 'acute promyelocytic leukemia with PML-rara', 'acute promyelocytic leukemia with t(15;17)(q22;q12); PML-rara', 'acute myeloid leukaemia M3', 'FAB M3', 'promyelocytic leukaemia', 'AML M3', 'APML', 'APML - acute promyelocytic leukemia', 'acute promyelocytic leukaemia with t(15;17)(q22;q12); PML/rara', 'AML with t(15;17)(q22;q12)', 'acute promyelocytic leukaemia with t(15;17)(q22;q12); PML-rara', 'acute promyelocytic leukaemia with PML-rara', 'acute promyelocytic leukemia with t(15;17)(q22;q12); PML/rara', 'acute myeloid leukaemia with t(15;17)(q22;q12);(PML/RARalpha) and variants', 'acute myeloid leukemia M3', 'leukemia acute promyelocytic somatic', 'promyelocytic leukemia', 'APML - acute promyelocytic leukaemia', 'acute myeloblastic leukemia type 3', 'leukemia acute promyelocytic', 'papillary renal cell carcinoma', 'chromophil carcinoma of kidney', 'papillary (chromophil) renal cell carcinoma', 'papillary renal cell adenocarcinoma', 'papillary renal cell cancer', 'sporadic papillary renal cell carcinoma', 'papillary kidney carcinoma', 'HPRCC', 'chromophil carcinoma of the kidney', 'chromophil renal cell carcinoma', 'renal cell carcinoma papillary type 1', 'papillary renal cell carcinoma bilateral - (subtype)', 'RCCP', 'papillary renal cell carcinoma multiple - (subtype)', 'renal adenocarcinoma', 'RCCP1', 'chromophil RCC', 'renal cell carcinoma papillary 1', 'papillary renal carcinoma malignant - (subtype)', 'papillary renal cell carcinoma familial - (subtype)', 'papillary renal cell carcinoma sporadic - (subtype)', 'anaplastic astrocytoma', 'grade III astrocytoma', 'grade III astrocytic neoplasm', 'astrocytoma anaplastic malignant', 'malignant astrocytoma', 'grade III astrocytic tumor', 'grade III astrocytic tumour', 'mesothelioma', 'Central Nervous System Neoplasm', 'tumour of central nervous system', 'tumour of CNS', 'tumor of central nervous system', 'CNS tumor', 'tumour of the CNS', 'tumour of the central nervous system', 'central nervous system neoplasm', 'neoplasm of central nervous system', 'brain/spinal cord tumour', 'tumor of the central nervous system', 'CNS tumour', 'central nervous system neoplasm (disease)', 'tumor of the CNS', 'CNS neoplasm', 'neoplasm of the central nervous system', 'neoplasm of CNS', 'tumor of CNS', 'central nervous system tumour', 'central nervous system tumor', 'brain/spinal cord tumor', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'uterine sarcoma', 'body of uterus sarcoma', 'uterine corpus sarcoma', 'sarcoma of the body of uterus', 'uterine body sarcoma', 'sarcoma of the uterine body', 'uterus sarcoma', 'sarcoma of corpus uteri', 'corpus uteri sarcoma', 'sarcoma of uterine corpus', 'sarcoma of uterus', 'sarcoma of the uterine corpus', 'sarcoma of the corpus uteri', 'sarcoma of uterine body', 'sarcoma of body of uterus', 'uterine sarcoma/mesenchymal', 'sarcoma of the uterus', 'urethra cancer', 'malignant urethral neoplasm', 'malignant urethra tumour', 'malignant tumour of the urethra', 'urethral Ca', 'malignant tumor of urethra', 'malignant urethra tumor', 'malignant tumor of the urethra', 'malignant urethral tumor', 'malignant neoplasm of the urethra', 'malignant urethra neoplasm', 'malignant neoplasm of urethra', 'malignant tumour of urethra', 'malignant urethral tumour', 'cancer of urethra', 'urethral cancer', 'papillary thyroid carcinoma', 'papillary cancer of the thyroid gland', 'papillary carcinoma of the thyroid', 'thyroid gland papillary carcinoma', 'papillary carcinoma of thyroid', 'papillary carcinoma of the thyroid gland', 'PTC', 'papillary thyroid cancer', 'papillary cancer of the thyroid', 'thyroid gland papillary cancer', 'papillary thyroid gland carcinoma', 'papillary carcinoma of thyroid gland', 'thyroid papillary carcinoma', 'papillary cancer of thyroid gland', 'papillary cancer of thyroid', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'pleomorphic rhabdomyosarcoma', 'anaplastic rhabdomyosarcoma', 'pleomorphic rhabdomyosarcoma adult type', 'resectable malignant neoplasm of the liver', 'hepatic cancer', 'primary malignant neoplasm of liver', 'malignant tumour of liver', 'non-resectable primary hepatic malignant neoplasm', 'primary liver cancer', 'malignant neoplasm of liver primary', 'cancer of liver', 'malignant liver neoplasm', 'malignant tumor of liver', 'malignant neoplasm of liver not specified as primary or secondary', 'malignant neoplasm of liver', 'malignant hepato-biliary neoplasm', 'hepatic neoplasm', 'ca liver - primary', 'Ca liver - primary', 'primary malignant liver neoplasm', 'Resectable malignant neoplasm of liver', 'primary tumor of the liver', 'primary tumour of the liver', 'primary cancer of liver', 'clear cell renal carcinoma', 'kidney clear cell adenocarcinoma', 'RCC clear cell adenocarcinoma', 'conventional (clear cell) renal cell adenocarcinoma', 'renal clear cell carcinoma', 'clear cell adenocarcinoma of the kidney', 'hypernephroma', 'conventional (clear cell) renal cell carcinoma', 'clear cell adenocarcinoma of kidney', 'clear cell renal cell cancer', 'renal cell carcinoma clear cell adenocarcinoma', 'clear cell renal cell carcinoma', 'clear cell adenocarcinoma kidney', 'kidney clear cell carcinoma', 'renal clear cell adenocarcinoma', 'conventional renal cell carcinoma', 'clear cell carcinoma of the kidney', 'Grawitz tumour', 'clear cell carcinoma of kidney', 'Grawitz tumor', 'clear cell kidney carcinoma', 'clear-cell metastatic renal cell carcinoma', 'chronic lymphocytic leukemia', 'B-cell lymphocytic leukaemia', 'CLL', 'B-CLL', 'BCLL', 'chronic lymphogenous leukaemia', 'B cell lymphocytic leukemia', 'chronic lymphatic leukaemia', 'B cell CLL', 'B-cell lymphocytic leukemia', 'small lymphocytic lymphoma', 'B-cell chronic lymphoid leukaemia', 'lymphoplasmacytic leukaemia', 'B-cell chronic lymphocytic leukemia', 'B-cell chronic lymphogenous leukemia', 'B-cell chronic lymphogenous leukaemia', 'B-cell chronic lymphoid leukemia', 'B cell chronic lymphocytic leukaemia', 'chronic B-cell lymphocytic leukaemia', 'B cell lymphocytic leukaemia', 'chronic lymphocytic leukemia (CLL)', 'B-cell CLL', 'chronic lymphocytic leukaemia (CLL)', 'chronic lymphatic leukemia', 'chronic B-cell lymphocytic leukemia', 'B cell chronic lymphocytic leukemia', 'lymphoplasmacytic leukemia', 'hematopoeitic - chronic lymphocytic leukemia (CLL)', 'hematopoeitic - chronic lymphocytic leukaemia (CLL)', 'chronic lymphogenous leukemia', 'chronic lymphocytic leukaemia', 'leukemia chronic LYMPHOCYTIC', 'leukemia chronic lymphatic', 'leukemia lymphocytic chronic', 'rectal carcinoma', 'cancer of the rectum', 'rectum carcinoma', 'prostate adenocarcinoma', 'adenocarcinoma of prostate', 'adenocarcinoma of the prostate', 'prostate gland adenocarcinoma', 'prad', 'anaplastic large cell lymphoma', 'primary systemic ALCL', 'CD30 positive anaplastic large cell lymphoma', 'Ki-1+ ALCL', 'ALCL', 'Ki-1 lymphoma', 'CD30 Positive anaplastic large cell lymphoma', 'Ki-1+ anaplastic large cell lymphoma', 'sACL', 'Ki-1 positive anaplastic large cell lymphoma', 'acute lymphoblastic leukemia', 'lymphoblastic leukaemia', 'lymphoblastic leukemia', 'acute lymphogenous leukaemia', 'acute lymphoid leukemia', 'acute lymphoblastic leukaemia (ALL)', 'precursor Lymphoblasic leukaemia', 'acute lymphoid leukaemia', 'acute lymphoblastic leukemia/lymphoma', 'acute lymphocytic leukemia', 'lymphoblastic leukemia acute', 'acute lymphocytic leukemias', 'precursor lymphoblastic leukemia', 'acute lymphocytic leukaemia', 'leukemia lymphoblastic malignant', 'ALL - acute lymphocytic leukemia', 'ALL - acute lymphocytic leukaemia', 'precursor cell lymphoblastic leukaemia', 'acute lymphoblastic leukemia (disease)', 'acute lymphoblastic leukaemia (disease)', 'ALL', 'acute lymphogenous leukemia', 'acute lymphoblastic leukemia (ALL)', 'precursor lymphoblastic leukaemia', 'precursor cell lymphoblastic leukemia', 'precursor Lymphoblasic leukemia', 'osteosarcoma', 'bone tissue neoplasm', 'osteogenic sarcoma', 'osteosarcoma malignant', 'OS', 'osteosarcoma (disease)', 'sarcoma of osteoid', 'osteoid sarcoma', 'oropharyngeal carcinoma', 'oropharyngeal throat cancer', 'oropharyngeal cancer', 'cancer of oropharynx', 'cancer of the oropharynx', 'carcinoma of oropharynx', 'oropharynx carcinoma', 'carcinoma of the oropharynx', 'Uterine Carcinosarcoma', 'malignant mixed mesodermal (Müllerian) tumor of the uterus', 'uterine malignant mixed mesodermal (Mullerian) tumor', 'carcinosarcoma of the uterus', 'uterine malignant mixed mesodermal (Müllerian) tumour', 'uterine carcinosarcoma', 'malignant mixed mesodermal (Müllerian) tumour of the uterus', 'malignant mixed mesodermal (Mullerian) tumor of the uterus', 'mixed mullerian sarcoma of uterus', 'uterine malignant mixed mesodermal (Mullerian) tumour', 'uterine malignant mixed mesodermal (Müllerian) tumor', 'uterus carcinosarcoma', 'malignant mixed mesodermal (Mullerian) tumour of the uterus', 'uterine carcinosarcoma/uterine malignant mixed mullerian tumor', 'uterine carcinosarcoma/uterine malignant mixed mullerian tumour', 'Mantle cell lymphoma', 'classical mantle cell lymphoma', 'LCM', 'MCL', 'mantle cell lymphoma', 'mantle zone lymphoma', 'lymphoma mantle cell', 'diffuse large B-cell lymphoma', 'DLBCL', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'colorectal adenocarcinoma', 'colorectum adenocarcinoma', 'adenocarcinoma of the large bowel', 'colorectal (colon or rectal) adenocarcinoma', 'adenocarcinoma of large bowel', 'large intestine adenocarcinoma', 'adenocarcinoma of the large intestine', 'large bowel adenocarcinoma', 'adenocarcinoma of large intestine', 'tongue neoplasm', 'NEOPL TONGUE', 'Neoplasms Tongue', 'Cancers Tongue', 'NEOPL ORAL', 'Cancer of Tongue', 'tongue neoplasm (disease)', 'Oral Neoplasm', 'tongue tumor', 'Tongue Cancers', 'neoplasm of the tongue', 'Tongue Cancer', 'Neoplasm Tongue', 'Cancer Tongue', 'Neoplasms Oral', 'neoplasm of tongue', 'Cancer of the Tongue', 'Tongue Neoplasms', 'Cancer Oral', 'tumor of the tongue', 'tumour of the tongue', 'ORAL NEOPL', 'Oral Cancers', 'Oral Cancer', 'Cancers Oral', 'tumor of tongue', 'tongue tumour', 'tumour of tongue', 'TONGUE NEOPL', 'Neoplasm Oral', 'Oral Neoplasms', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'renal cell adenocarcinoma', 'gliosarcoma', 'glioblastoma with a sarcomatous component', 'glioblastoma with sarcomatous component', 'sarcomatous glioblastoma', 'multiple myeloma', 'myelomatosis', 'plasma cell myeloid neoplasm', 'Kahler disease', 'myeloma multiple', 'myeloma', 'multiple myeloma susceptibility to Somatic mutation', 'myeloid neoplasm of plasma cell', 'plasma cell myeloma', 'multiple myeloma resistance to Somatic mutation', 'myeloma plasma cell malignant', 'medullary plasmacytoma', 'multiple myeloma/plasma cell myeloma', """"""""Kahler's disease"""""""", 'Al amyloidosis', 'myeloma - multiple', 'amyloidosis systemic', 'peritoneum cancer', 'peritoneal cancer', 'peritoneal cavity cancer', 'malignant peritoneal neoplasm', 'cancer of peritoneum', 'malignant peritoneum neoplasm', 'cancer of the peritoneum', 'malignant neoplasm of peritoneum', 'peritoneal neoplasm', 'tumor of the bladder', 'tumour of the bladder', 'malignant neoplasm of the urinary bladder', 'malignant neoplasm bladder', 'malignant urinary bladder tumor', 'malignant tumor of the bladder', 'malignant tumor of bladder', 'urinary bladder malignant tumour', 'malignant tumor of the urinary bladder', 'urinary bladder malignant neoplasm', 'malignant neoplasm of the bladder', 'malignant bladder neoplasm', 'malignant bladder tumour', 'malignant tumour of the urinary bladder', 'malignant urinary bladder tumour', 'malignant urinary bladder neoplasm', 'malignant neoplasm urinary bladder', 'malignant bladder tumor', 'bladder cancer somatic', 'malignant tumor urinary bladder', 'malignant tumour of bladder', 'malignant tumor of urinary bladder', 'malignant tumour of the bladder', 'malignant tumour of urinary bladder', 'malignant neoplasm of bladder', 'malignant neoplasm of urinary bladder', 'urinary bladder malignant tumor', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'Vascular endothelial growth factor receptor 2', 'KDR', 'FLK1', 'VEGFR2', 'CD309', 'VEGFR-2', 'FLK-1', 'VEGFR', 'Fetal liver kinase 1', 'Kinase insert domain receptor', 'Protein-tyrosine kinase receptor flk-1', 'vascular endothelial growth factor receptor 2', 'fetal liver kinase 1', 'fetal liver kinase-1', 'kinase insert domain receptor (a type III receptor tyrosine kinase)', 'protein-tyrosine kinase receptor Flk-1', 'soluble VEGFR2', 'tyrosine kinase growth factor receptor', 'kinase insert domain receptor', 'Proto-oncogene tyrosine-protein kinase receptor Ret', 'Soluble RET kinase fragment', 'Extracellular cell-membrane anchored RET cadherin 120 kDa fragment', 'RET', 'CDHF12', 'CDHR16', 'RET51', 'Cadherin family member 12', 'Proto-oncogene c-Ret', 'cadherin-related family member 16', 'RET receptor tyrosine kinase', 'rearranged during transfection', 'HSCR1', 'MEN2A', 'MEN2B', 'MTC1', 'RET-ELE1', 'proto-oncogene","","","","","","",,"",
CHEMBL1336,RAF1,CAND2,LVEF,"","",SORAFENIB,Yes,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['pancreatic neoplasm', 'pancreas neoplasm (disease)', 'Neoplasm Pancreas', 'pancreas neoplasm', 'Neoplasm Pancreatic', 'PANCREAS NEOPL', 'tumour of the pancreas', 'Neoplasms Pancreas', 'Pancreatic Neoplasms', 'tumor of the pancreas', 'neoplasm of the pancreas', 'Pancreas Neoplasm', 'pancreatic tumor', 'Neoplasms Pancreatic', 'pancreas tumour', 'pancreatic cancer', 'pancreas tumor', 'PANCREATIC NEOPL', 'pancreatic tumour', 'tumour of pancreas', 'neoplasm of pancreas', 'NEOPL PANCREATIC', 'tumor of pancreas', 'Pancreas Neoplasms', 'pancreas', 'follicular thyroid carcinoma', 'follicular cancer of the thyroid gland', 'thyroid gland follicular cancer', 'follicular cancer of the thyroid', 'well-differentiated follicular carcinoma', 'follicular cancer of thyroid', 'follicular cancer of thyroid gland', 'thyroid gland follicular carcinoma', 'thyroid gland adenocarcinoma', 'follicular carcinoma of the thyroid gland', 'follicular carcinoma', 'thyroid follicular carcinoma', 'well-differentiated follicular adenocarcinoma', 'follicular thyroid gland carcinoma', 'follicular adenocarcinoma well differentiated (morphologic abnormality)', 'carcinoma follicular cell malignant', 'carcinoma of thyroid follicle', 'follicular adenocarcinoma (morphologic abnormality)', 'follicular adenocarcinoma', 'follicular carcinoma of thyroid gland', 'thyroid follicle carcinoma', 'follicular carcinoma of the thyroid', 'follicular thyroid cancer', 'follicular adenocarcinoma well differentiated', 'follicular carcinoma of thyroid', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'therapy related acute myeloid leukemia and myelodysplastic syndrome', 'therapy-related AML and myelodysplastic syndrome', 'Secondary Acute myeloblastic Leukaemia', 'Secondary Acute granulocytic Leukemia', 'Secondary Acute granulocytic Leukaemia', 'Secondary AGL', 'secondary acute myeloid leukemia', 'secondary AML', 'Secondary Acute myeloid Leukemia (AML)', 'Secondary Acute myelocytic Leukaemia', 'Secondary Acute myelocytic Leukemia', 'Secondary Acute myeloid Leukaemia (AML)', 'secondary acute myeloid leukaemia', 'Secondary Acute myelogenous Leukemia', 'Secondary Acute myelogenous Leukaemia', 'Secondary Acute myeloblastic Leukemia', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'biliary tract cancer', 'cancer of biliary tree', 'biliary tree cancer', 'malignant tumour of biliary tract', 'malignant neoplasm of biliary tree', 'malignant tumor of biliary tract', 'malignant biliary tree neoplasm', 'adenocarcinoma', 'adenocarcinoma malignant', 'adenocarcinoma NOS (morphologic abnormality)', 'adenocarcinomas', 'adenocarcinoma no subtype (morphologic abnormality)', 'ADNOS', 'small cell carcinoma', 'small cell car. (extrapulmonary)', 'small cell neuroendocrine carcinoma', 'small cell NEC', 'small cell cancer', 'small cell carcinoma (extrapulmonary)', 'oat cell cancer', 'small cell carcinoma - intermediate cell', 'small cell carcinoma intermediate cell (morphologic abnormality)', 'intermediate cell small cell carcinoma', 'small cell carcinoma intermediate cell', 'nasal cavity and paranasal sinus squamous cell carcinoma', 'nasal cavity and paranasal sinus squamous cell cancer', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'Ewing sarcoma/peripheral primitive neuroectodermal tumor', 'EFTs', """"""""tumors of the Ewing's family"""""""", """"""""Ewing's sarcoma/peripheral primitive neuroectodermal tumor"""""""", """"""""Ewing's sarcoma/peripheral primitive neuroectodermal tumour"""""""", 'Ewing family of tumours', """"""""Ewing's family of tumours"""""""", """"""""Ewing's family of tumors"""""""", 'Ewing sarcoma family of tumors', 'Ewing sarcoma family of tumours', """"""""tumours of the Ewing's family"""""""", 'Ewing family of tumors', """"""""tumours of Ewing's family"""""""", """"""""tumors of Ewing's family"""""""", 'Ewing sarcoma/peripheral PNET', 'pulmonary arterial hypertension', 'PPH1', 'PHT - Pulmonary hypertension', 'pulmonary hypertension (disorder)', 'pulmonary hypertension primary 1', 'Syndrome Ayerza', 'Ayerza-Arrilaga Syndrome', 'PULM HYPERTENSION', 'PAH', 'Ayerza Arrilaga Syndrome', 'Ayerza Syndrome', 'pulmonary hypertension', 'Pulmonary hypertension NOS', 'HYPERTENSION PULM', 'Syndrome Ayerza-Arrilaga', 'Hypertension Pulmonary', """"""""Ayerza's Syndrome"""""""", 'Ayerzas Syndrome', 'PVOD/PCH', 'PAH with overt features of venous/capillaries involvement', 'idiopathic pulmonary hypertension', 'PPH', 'male breast carcinoma', 'male breast cancer', 'carcinoma of male breast', 'carcinoma of the Male breast', 'neoplasm of male breast', 'malignant neoplasm of male breast', 'Male breast carcinoma', 'Male breast cancer', 'carcinoma of Male breast', 'breast cancer in men', 'breast cancer male', 'myeloid sarcoma', 'extramedullary myeloid tumor', 'granulocytic sarcoma', 'sarcoma myeloid malignant', 'chloroma', 'extramedullary myeloid tumour', 'MS', 'hypopharyngeal carcinoma', 'cancer of the hypopharynx', 'cancer of hypopharynx', 'hypopharyngeal cancer', 'hypopharyngeal throat cancer', 'hypopharynx carcinoma', 'carcinoma of the hypopharynx', 'carcinoma of hypopharynx', 'myelodysplastic syndrome', 'MDS', 'myelodysplastic neoplasm', 'MDS unclassifiable', 'myelodysplastic syndrome somatic', 'myelodysplasia', 'oligoblastic leukaemia', 'myelodysplastic syndromes', 'MDS-U', 'dysmyelopoietic syndrome', 'oligoblastic leukemia', 'preleukemia', 'myelodysplastic syndrome/neoplasm', 'hematopoeitic - myelodysplastic syndrome (MDS)', 'smouldering leukaemia', 'myelodysplastic syndrome unclassifiable', 'smoldering leukemia', 'myelodysplastic syndrome susceptibility to', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'chromophobe renal cell carcinoma', 'kidney chromophobe', 'chromophobe adenocarcinoma', 'chromophobe cell carcinoma of the kidney', 'chromophobe carcinoma', 'chromophobe renal cell adenocarcinoma', 'chromophobe cell carcinoma of kidney', 'renal cell carcinoma chromophobe cell', 'chromophobe renal cell cancer', 'chromophobe carcinoma of the kidney', 'chromophobe carcinoma of kidney', 'renal cell carcinoma chromophobe type', 'CHRCC', 'ChRCC', 'CRCC', 'thyroid neoplasm', 'tumor of the thyroid gland', 'tumour of the thyroid', 'neoplasm of thyroid gland', 'Thyroid Gland Neoplasm', 'NEOPL THYROID', 'neoplasm of the thyroid gland', 'tumour of thyroid', 'tumor of thyroid gland', 'thyroid gland tumour', 'tumor of thyroid', 'thyroid neoplasms', 'thyroid gland neoplasm', 'thyroid tumor', 'tumor of the thyroid', 'neoplasm of thyroid', 'THYROID NEOPL', 'thyroid gland tumor', 'Neoplasms Thyroid', 'neoplasm of the thyroid', 'tumour of the thyroid gland', 'Adenoma Thyroid', 'tumour of thyroid gland', 'Neoplasm Thyroid', 'Thyroid Neoplasms', 'thyroid gland neoplasm (disease)', 'THYROID', 'carcinoma of liver and intrahepatic biliary tract', 'liver cancer', 'cancer of liver', 'cancer of the liver', 'liver/hepatobiliary cancer', 'liver carcinoma', 'cancer of the liver and intrahepatic biliary tract', 'carcinoma of liver', 'cancer of liver and intrahepatic biliary tract', 'hepatic cancer', 'liver and intrahepatic bile duct cancer', 'liver and intrahepatic bile duct carcinoma', 'carcinoma of liver and IBT', 'liver and intrahepatic biliary tract carcinoma', 'liver and intrahepatic biliary tract cancer', 'primary liver carcinoma', 'hepatocellular carcinoma plus intrahepatic cholangiocarcinoma', """"""""Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of soft tissues"""""""", """"""""Kaposi's sarcoma (disease)"""""""", 'Kaposi sarcoma', """"""""Kaposi's sarcoma of cornea"""""""", 'KS', """"""""Kaposi's sarcoma of soft tissue"""""""", """"""""Kaposi's sarcoma of conjunctiva"""""""", """"""""Kaposi's sarcoma of palate"""""""", """"""""Kaposi's sarcoma of lung"""""""", """"""""palate Kaposi's sarcoma"""""""", """"""""conjunctival Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of anus"""""""", """"""""corneal Kaposi's sarcoma"""""""", 'multiple hemorrhagic sarcoma', """"""""gastric Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of skin"""""""", """"""""gallbladder Kaposi's sarcoma"""""""", """"""""lymph node Kaposi's sarcoma"""""""", """"""""cutaneous Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of lymph nodes"""""""", """"""""lymphadenopathic Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of oesophagus"""""""", """"""""prostate Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of penis"""""""", """"""""soft tissue Kaposi's sarcoma"""""""", """"""""pulmonary Kaposi's sarcoma"""""""", """"""""cardiac Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of the prostate"""""""", """"""""Kaposi's sarcoma skin"""""""", """"""""Kaposi's sarcoma of the CNS"""""""", """"""""intestinal Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of central nervous system"""""""", """"""""Kaposi's sarcoma of the gallbladder"""""""", """"""""anal Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of gastrointestinal sites"""""""", """"""""Kaposi's sarcoma lung"""""""", """"""""penis Kaposi's sarcoma"""""""", """"""""esophageal Kaposi's sarcoma"""""""", """"""""central nervous system Kaposi's sarcoma"""""""", """"""""Kaposi's sarcoma of heart"""""""", """"""""Kaposi's sarcoma of esophagus"""""""", 'Kaposi sarcoma herpesvirus', """"""""Kaposi's sarcoma-associated herpesvirus (KSHV)"""""""", 'KSHV', 'Mediterranean Kaposi sarcoma', 'non AIDS related Kaposi sarcoma', """"""""African lymphadenopathic Kaposi's sarcoma"""""""", 'HHV8', 'human herpesvirus 8', 'renal pelvis/ureter urothelial carcinoma', 'renal pelvis and ureter transitional cell carcinoma', 'transitional cell cancer of the renal pelvis and ureter', 'renal pelvis and ureter urothelial carcinoma', 'TCC of the renal pelvis and ureter', 'TCC of renal pelvis and ureter', 'renal pelvis and ureter transitional cell cancer', 'renal pelvis and ureter TCC', 'transitional cell carcinoma of renal pelvis and ureter', 'transitional cell cancer of renal pelvis and ureter', 'urothelial carcinoma of the renal pelvis and ureter', 'soft tissue sarcoma', 'malignant soft tissue tumor', 'malignant soft tissue tumour', 'malignant mesenchymal tumor', 'sarcoma of the soft tissue', 'soft part sarcoma', 'sarcoma of soft tissue', 'malignant mesenchymal tumour', 'connective tissue sarcoma', 'non-Rhabdo. soft tissue sarcoma', 'core binding factor acute myeloid leukemia', 'CBF-AML', 'Malignant Pancreatic Neoplasm', 'malignant neoplasm of body of pancreas', 'Ca body of pancreas', 'malignant neoplasm of pancreas', 'malignant pancreas neoplasm', 'Ca head of pancreas', 'malignant neoplasm of head of pancreas', 'malignant pancreatic neoplasm', 'malignant neoplasm of tail of pancreas', 'malignant neoplasm of the pancreas', 'Ca tail of pancreas', 'colorectal neoplasm', 'colorectal tumour', 'tumor of the large bowel', 'colorectum tumour', 'large intestine tumor', 'neoplasm of colorectum', 'tumor of colorectum', 'large intestine neoplasm', 'tumor of large bowel', 'large bowel tumour', 'colorectum neoplasm (disease)', 'neoplasm of large bowel', 'large bowel tumor', 'large intestinal neoplasm', 'large intestine tumour', 'colorectum neoplasm', 'colorectum tumor', 'tumour of the large bowel', 'colorectal tumor', 'tumour of colorectum', 'tumour of large bowel', 'large bowel neoplasm', 'neoplasm of the large bowel', 'diffuse large B-cell lymphoma', 'DLBCL', 'acute monocytic leukemia', 'monocytic leukemia', 'monocytic leukaemia', 'acute monocytic leukemia morphology', 'leukemia monocytic malignant', 'AML M5', 'acute monocytic leukemia FAB M5', 'acute monoblastic leukemia and acute monocytic leukemia', 'acute monocytic leukaemia without mention of remission', 'monocytic leukemia acute', 'acute monoblastic leukaemia and acute monocytic leukaemia', 'acute monocytic leukemia (FAB M5b)', 'acute monocytic leukemia (FAB M5B)', 'acute monocytic leukemia morphology (morphologic abnormality)', 'acute monocytic leukaemia (FAB M5b)', 'acute monocytic leukaemia (FAB M5B)', 'acute monocytic leukemia without mention of remission', 'acute myeloblastic leukaemia type 5', 'acute monoblastic leukaemia', 'AML-M5', 'acute myeloblastic leukemia type 5', 'leukemia acute monocytic', 'acute monoblastic/monocytic leukemia', 'acute monoblastic leukemia', 'acute monoblastic/monocytic leukaemia', 'grade III glioma', 'anaplastic glioma', 'WHO grade III glioma', 'cervical carcinoma', 'cervix cancer', 'cancer of the uterine cervix', 'uterine cervix cancer', 'cancer of the cervix', 'cervical cancer NOS', 'cancer of uterine cervix', 'cancer of cervix', 'cervical cancer', 'carcinoma of cervix', 'uterine cervix carcinoma', 'carcinoma of the cervix', 'carcinoma of the cervix uteri', 'carcinoma of uterine cervix', 'carcinoma cervix uteri', 'carcinoma of cervix uteri', 'carcinoma of the uterine cervix', 'cervix uteri carcinoma', 'cervix carcinoma', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'laryngeal squamous cell carcinoma', 'squamous cell carcinoma of the larynx', 'laryngeal epidermoid carcinoma', 'squamous cell carcinoma of larynx', 'LSCC', 'larynx squamous cell carcinoma', 'epidermoid carcinoma of the larynx', 'larynx epidermoid carcinoma', 'epidermoid carcinoma of larynx', 'laryngeal throat squamous cell cancer', 'LXSC', 'malignant peripheral nerve sheath tumor', 'neurofibrosarcoma', 'malignant neurilemoma', 'MPNST with glandular differentiation', 'Neurosarcoma [obs]', 'Peripheral Nerve Sheath Tumors Malignant', 'Malignant Peripheral Nerve Sheath Tumour', 'malignant tumour of the peripheral nerve sheath', 'malignant peripheral nerve sheath tumor (disorder)', 'Neurosarcoma', 'Melanotic psammomatous MPNST', 'malignant peripheral nerve sheath tumour [dup] (morphologic abnormality)', 'MPNST', 'Perineurioma', 'malignant neoplasm of peripheral nerve sheath', 'malignant schwannoma', 'malignant tumor of the peripheral nerve sheath', 'Malignant peripheral nerve sheath tumor (morphologic abnormality)', 'MPNST - Malignant peripheral nerve sheath tumor', 'MPNST - Malignant peripheral nerve sheath tumour', 'malignant peripheral nerve sheath tumor [dup] (morphologic abnormality)', 'MPNST with mesenchymal differentiation', 'malignant tumor of peripheral nerve sheath', 'Malignant Peripheral Nerve Sheath Neoplasm', 'neurogenic sarcoma', 'Malig. periph. nerve sheath tum.', 'Malignant Tumor of Peripheral Nerve Sheath', 'neurofibrosarcoma malignant', 'malignant peripheral nerve sheath tumour (morphologic abnormality)', 'Neurogenic sarcoma', 'Malignant Schwannoma', 'Malignant Neurilemmoma', 'malignant peripheral nerve sheath tumor (morphologic abnormality)', 'Neurofibrosarcoma', 'malignant neoplasm of the peripheral nerve Sheath', 'Malignant peripheral nerve sheath tumor [dup] (morphologic abnormality)', 'Neurofibrosarcoma [obs]', 'Melanotic MPNST', 'Neurogenic sarcoma [obs]', 'Perineuriomas', 'MPNSTs', 'Malignant Neoplasm of Peripheral Nerve Sheath', 'malignant neurofibroma', 'Malignant Peripheral Nerve Sheath Tumors', 'malignant neoplasm of the peripheral nerve sheath', 'malignant peripheral nerve sheath neoplasm', 'schwannoma malignant', 'malignant tumour of peripheral nerve sheath', 'malignant neurilemmoma', 'Malignant Tumor of the Peripheral Nerve Sheath', 'Epithelioid MPNST', 'Malignant Neurilemoma', 'metastatic prostate cancer', 'prostate carcinoma metastatic', 'metastatic prostate carcinoma', 'prostate cancer metastatic', 'cholangiocarcinoma', 'bile duct cancer', 'intrahepatic bile duct cancer (cholangiocarcinoma)', 'cholangiocarcinoma malignant', 'CC', 'adult primary cholangiocellular carcinoma', 'Cholangiocellular carcinoma', 'cholangiocarcinoma intrahepatic and extrahepatic bile ducts (adenocarcinoma)', 'CCA', 'cholangiosarcoma', 'adult primary cholangiocarcinoma', 'Cholangiocar.- intra/extrahepatic', 'lymphoma', """"""""lymphoma (Hodgkin's and non-Hodgkin's)"""""""", 'lymphoma (Hodgkin and non-Hodgkin)', 'lymphomatous', 'lymphoid cancer', 'malignant lymphoma', 'lymphoma malignant', 'MLYM', 'rhabdomyosarcoma', 'rhabdomyosarcoma malignant', 'rhabdomyosarcoma (disease)', 'squamous cell carcinoma', 'squamous cell carcinoma NOS (morphologic abnormality)', 'epidermoid cell cancer', 'epidermoid carcinoma', 'malignant epidermoid cell neoplasm', 'malignant epidermoid cell tumour', 'carcinoma squamous cell malignant', 'malignant squamous cell tumor', 'malignant epidermoid cell tumor', 'malignant squamous cell neoplasm', 'malignant squamous cell tumour', 'squamous cell cancer', 'squamous carcinoma', 'SCC', 'squamous cell epithelioma', 'squamous cell carcinoma (morphologic abnormality)', 'mucosal melanoma', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'leukemia', 'leukaemia (disease)', 'leukemias general', 'leukemias', 'leukemia (disease)', 'blood (leukemia)', 'leukemia disease', 'leukemia malignant', 'leukaemia NOS', 'Hepatopulmonary Syndrome', 'hepatopulmonary syndrome', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'prostate cancer', 'tumor of the prostate', 'prostatic neoplasm', 'tumour of the prostate', 'prostate neoplasm', 'malignant neoplasm of the prostate', 'malignant neoplasm of prostate gland', 'malignant prostate tumor', 'malignant prostate tumour', 'malignant prostate gland neoplasm', 'malignant neoplasm of prostate', 'malignant tumour of prostate', 'malignant prostate neoplasm', 'prostate gland cancer', 'prostatic cancer', 'cancer of prostate gland', 'malignant tumor of the prostate', 'malignant tumor of prostate', 'malignant tumour of the prostate', 'NGP - new growth of prostate', 'hereditary prostate cancer', 'prostate cancer familial', 'testicular carcinoma', 'testicular tumour', 'testis neoplasm', 'testicular tumor', 'malignant testis neoplasm', 'malignant tumor of the testis', 'malignant testicular tumour', 'testicular cancer', 'malignant neoplasm of testis', 'cancer of testis', 'malignant testicular tumor', 'testis cancer', 'malignant tumor of testis', 'malignant testicular neoplasm', 'malignant neoplasm of the testis', 'malignant tumour of testis', 'malignant tumour of the testis', 'paediatric testicular neoplasm', 'Keloid', 'keloid', 'keloids', 'Thymic Carcinoma', 'thymoma malignant (morphologic abnormality)', 'carcinoma of thymus', 'thymoma malignant', 'thymoma type C (morphologic abnormality)', 'thymoma type C', 'malignant thymoma', 'thymic carcinoma', 'thymic carcinoma (excluding well differentiated thymic carcinoma)', 'thymus carcinoma', 'type C thymoma', 'thymic carcinoma excluding well differentiated thymic carcinoma', 'THYC', 'Poorly Differentiated Thyroid Gland Carcinoma', 'poorly differentiated thyroid carcinoma', 'insular carcinoma', 'poorly differentiated thyroid gland carcinoma', 'poorly differentiated carcinoma of the thyroid gland', 'poorly differentiated carcinoma of thyroid gland', 'thyroid gland poorly differentiated carcinoma', 'poorly differentiated thyroid gland cancer', 'poorly differentiated thyroid cancer', 'kidney disease', 'renal system disease', 'Kidney Disorder', 'disease or disorder of kidney', 'renal disorder', 'disorder of kidney', 'renal disease', 'disease of kidney', 'nephropathy', 'kidney diseases', 'kidney disorder', 'kidney disease or disorder', 'tongue neoplasm', 'NEOPL TONGUE', 'Neoplasms Tongue', 'Cancers Tongue', 'NEOPL ORAL', 'Cancer of Tongue', 'tongue neoplasm (disease)', 'Oral Neoplasm', 'tongue tumor', 'Tongue Cancers', 'neoplasm of the tongue', 'Tongue Cancer', 'Neoplasm Tongue', 'Cancer Tongue', 'Neoplasms Oral', 'neoplasm of tongue', 'Cancer of the Tongue', 'Tongue Neoplasms', 'Cancer Oral', 'tumor of the tongue', 'tumour of the tongue', 'ORAL NEOPL', 'Oral Cancers', 'Oral Cancer', 'Cancers Oral', 'tumor of tongue', 'tongue tumour', 'tumour of tongue', 'TONGUE NEOPL', 'Neoplasm Oral', 'Oral Neoplasms', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'rectal carcinoma', 'cancer of the rectum', 'rectum carcinoma', 'prostate adenocarcinoma', 'adenocarcinoma of prostate', 'adenocarcinoma of the prostate', 'prostate gland adenocarcinoma', 'prad', 'anaplastic large cell lymphoma', 'primary systemic ALCL', 'CD30 positive anaplastic large cell lymphoma', 'Ki-1+ ALCL', 'ALCL', 'Ki-1 lymphoma', 'CD30 Positive anaplastic large cell lymphoma', 'Ki-1+ anaplastic large cell lymphoma', 'sACL', 'Ki-1 positive anaplastic large cell lymphoma', 'acute lymphoblastic leukemia', 'lymphoblastic leukaemia', 'lymphoblastic leukemia', 'acute lymphogenous leukaemia', 'acute lymphoid leukemia', 'acute lymphoblastic leukaemia (ALL)', 'precursor Lymphoblasic leukaemia', 'acute lymphoid leukaemia', 'acute lymphoblastic leukemia/lymphoma', 'acute lymphocytic leukemia', 'lymphoblastic leukemia acute', 'acute lymphocytic leukemias', 'precursor lymphoblastic leukemia', 'acute lymphocytic leukaemia', 'leukemia lymphoblastic malignant', 'ALL - acute lymphocytic leukemia', 'ALL - acute lymphocytic leukaemia', 'precursor cell lymphoblastic leukaemia', 'acute lymphoblastic leukemia (disease)', 'acute lymphoblastic leukaemia (disease)', 'ALL', 'acute lymphogenous leukemia', 'acute lymphoblastic leukemia (ALL)', 'precursor lymphoblastic leukaemia', 'precursor cell lymphoblastic leukemia', 'precursor Lymphoblasic leukemia', 'osteosarcoma', 'bone tissue neoplasm', 'osteogenic sarcoma', 'osteosarcoma malignant', 'OS', 'osteosarcoma (disease)', 'sarcoma of osteoid', 'osteoid sarcoma', 'oropharyngeal carcinoma', 'oropharyngeal throat cancer', 'oropharyngeal cancer', 'cancer of oropharynx', 'cancer of the oropharynx', 'carcinoma of oropharynx', 'oropharynx carcinoma', 'carcinoma of the oropharynx', 'Uterine Carcinosarcoma', 'malignant mixed mesodermal (Müllerian) tumor of the uterus', 'uterine malignant mixed mesodermal (Mullerian) tumor', 'carcinosarcoma of the uterus', 'uterine malignant mixed mesodermal (Müllerian) tumour', 'uterine carcinosarcoma', 'malignant mixed mesodermal (Müllerian) tumour of the uterus', 'malignant mixed mesodermal (Mullerian) tumor of the uterus', 'mixed mullerian sarcoma of uterus', 'uterine malignant mixed mesodermal (Mullerian) tumour', 'uterine malignant mixed mesodermal (Müllerian) tumor', 'uterus carcinosarcoma', 'malignant mixed mesodermal (Mullerian) tumour of the uterus', 'uterine carcinosarcoma/uterine malignant mixed mullerian tumor', 'uterine carcinosarcoma/uterine malignant mixed mullerian tumour', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'uterine sarcoma', 'body of uterus sarcoma', 'uterine corpus sarcoma', 'sarcoma of the body of uterus', 'uterine body sarcoma', 'sarcoma of the uterine body', 'uterus sarcoma', 'sarcoma of corpus uteri', 'corpus uteri sarcoma', 'sarcoma of uterine corpus', 'sarcoma of uterus', 'sarcoma of the uterine corpus', 'sarcoma of the corpus uteri', 'sarcoma of uterine body', 'sarcoma of body of uterus', 'uterine sarcoma/mesenchymal', 'sarcoma of the uterus', 'urethra cancer', 'malignant urethral neoplasm', 'malignant urethra tumour', 'malignant tumour of the urethra', 'urethral Ca', 'malignant tumor of urethra', 'malignant urethra tumor', 'malignant tumor of the urethra', 'malignant urethral tumor', 'malignant neoplasm of the urethra', 'malignant urethra neoplasm', 'malignant neoplasm of urethra', 'malignant tumour of urethra', 'malignant urethral tumour', 'cancer of urethra', 'urethral cancer', 'papillary thyroid carcinoma', 'papillary cancer of the thyroid gland', 'papillary carcinoma of the thyroid', 'thyroid gland papillary carcinoma', 'papillary carcinoma of thyroid', 'papillary carcinoma of the thyroid gland', 'PTC', 'papillary thyroid cancer', 'papillary cancer of the thyroid', 'thyroid gland papillary cancer', 'papillary thyroid gland carcinoma', 'papillary carcinoma of thyroid gland', 'thyroid papillary carcinoma', 'papillary cancer of thyroid gland', 'papillary cancer of thyroid', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'gastroesophageal junction adenocarcinoma', 'adenocarcinoma of the esophagogastric junction', 'adenocarcinoma of cardioesophageal junction', 'adenocarcinoma of the EG junction', 'adenocarcinoma - GEJ', 'adenocarcinoma of gastroesophageal junction', 'adenocarcinoma of the gastroesophageal junction', 'adenocarcinoma of the GE junction', 'esophagogastric junction adenocarcinoma', 'adenocarcinoma of the cardioesophageal junction', 'esophagogastric adenocarcinoma', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'lung adenocarcinoma', 'adenocarcinoma of the lung', 'non-small cell lung adenocarcinoma', 'bronchogenic lung adenocarcinoma', 'nonsmall cell adenocarcinoma', 'LUAD', 'adenocarcinoma of lung', 'metastatic malignant neoplasm', 'malignant metastatic neoplasm', 'metastatic neoplasm malignant', 'metastatic cancer', 'hepatocellular carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'portal hypertension', 'Hypertension Portal', 'Portal Hypertensions', 'Hypertensions Portal', 'Cruveilhier-Baumgarten Syndrome', 'Portal hypertension (disorder)', 'Cruveilhier Baumgarten Syndrome', 'PHT - Portal hypertension', 'Syndrome Cruveilhier-Baumgarten', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'adrenal cortex carcinoma', 'adrenocortical cancer', 'adrenal cortical tumors', 'malignant neoplasm of adrenal cortex', 'malignant tumor of adrenal cortex', 'adrenal cortex cancer', 'cancer of the adrenal cortex', 'adrenal cortical tumours', 'malignant adrenocortical tumor', 'malignant adrenocortical tumour', 'malignant tumour of adrenal cortex', 'carcinoma of the adrenal cortex', 'adrenal cortical adenocarcinoma', 'ACC', 'cortical cell carcinoma', 'carcinoma adrenocortical malignant', 'carcinoma of adrenal cortex', 'adrenal cortex adenocarcinoma', 'adrenal cortical carcinoma', 'adrenocortical carcinoma (disease)', 'adrenocortical carcinoma', 'adrenal cortical carcinoma (morphologic abnormality)', 'adenocarcinoma adrenocortical malignant', 'salivary gland squamous cell carcinoma', 'salivary gland SCC', 'SCC of salivary gland', 'squamous cell carcinoma of salivary gland', 'SCC of the salivary gland', 'salivary gland epidermoid carcinoma', 'epidermoid carcinoma of the salivary gla","","","","","","",,"",
CHEMBL1946170,RAF1,CAND2,LVEF,"",United States,REGORAFENIB,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['biliary tract cancer', 'cancer of biliary tree', 'biliary tree cancer', 'malignant tumour of biliary tract', 'malignant neoplasm of biliary tree', 'malignant tumor of biliary tract', 'malignant biliary tree neoplasm', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'ovarian neoplasm', 'OVARY NEOPL', 'Ovary Neoplasm', 'ovarian tumour', 'ovary neoplasm (disease)', 'Neoplasm Ovary', 'Cancer of Ovary', 'ovarian tumors', 'neoplasm of ovary', 'ovary tumor', 'Neoplasms Ovary', 'tumour of the ovary', 'neoplasm of the ovary', 'Ovary Neoplasms', 'ovarian tumours', 'tumor of ovary', 'ovarian tumor', 'Neoplasm Ovarian', 'tumour of ovary', 'Neoplasms Ovarian', 'OVARIAN NEOPL', 'NEOPL OVARIAN', 'ovary tumour', 'tumor of the ovary', 'Ovarian Neoplasms', 'ovary neoplasm', 'angiosarcoma', 'vascular sarcoma', 'hemangiosarcoma malignant', 'sarcoma of blood vessel', 'malignant hemangioendothelioma', 'hemangiosarcoma', 'blood vessel sarcoma', 'angiosarcoma (disease)', 'malignant angioendothelioma', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'intrahepatic cholangiocarcinoma', 'peripheral cholangiocarcinoma', 'cholangiocarcinoma intrahepatic malignant', 'intrahepatic Cholangiocellular carcinoma', 'intrahepatic bile duct cancer (cholangiocarcinoma)', 'intrahepatic carcinoma of the bile duct', 'intrahepatic carcinoma of bile duct', 'intrahepatic bile duct carcinoma', 'ICC', 'intrahepatic cholangiocarcinoma (bile duct cancer)', 'IHCH', 'malignant renal pelvis neoplasm', 'malignant tumour of renal pelvis', 'malignant renal pelvis tumor', 'malignant tumour of the renal pelvis', 'malignant tumor of the renal pelvis', 'malignant tumor of renal pelvis', 'malignant renal pelvis tumour', 'renal pelvis cancer', 'malignant neoplasm of renal pelvis', 'malignant neoplasm of the renal pelvis', 'cancer of renal pelvis', 'ovarian carcinoma', 'ovarian cancer', 'ovarian epithelial cancer', 'carcinoma of ovary', 'ovary carcinoma', 'EOS', 'epithelial ovarian cancer', 'carcinoma of the ovary', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'bile duct carcinoma', 'bile duct cancer', 'bile duct cancer (including cholangiocarcinoma)', 'carcinoma of bile duct', 'gastric cancer', 'gastric neoplasm', 'malignant tumor of lesser curve of stomach', 'malignant tumour of body of stomach', 'malignant neoplasm of stomach', 'gastric cancer risk after h. pylori infection', 'malignant neoplasm of lesser curve of stomach', 'malignant gastric tumour', 'malignant gastric neoplasm', 'malignant tumour of greater curve of stomach', 'Ca lesser curvature - stomach', 'malignant stomach neoplasm', 'malignant tumor of greater curve of stomach', 'malignant tumor of body of stomach', 'malignant tumour of the stomach', 'malignant tumour of stomach', 'malignant tumor of the stomach', 'gastric cancer somatic', 'malignant tumour of lesser curve of stomach', 'malignant neoplasm of the stomach', 'malignant tumor of stomach', 'cancer of stomach', 'malignant gastric tumor', 'stomach cancer', 'Ca body - stomach', 'ca greater curvature of stomach', 'malignant neoplasm of body of stomach', 'gastric cancer intestinal', 'primary peritoneal carcinoma', 'EOPPC', 'serous surface papillary carcinoma', 'primary peritoneal cancer', 'Extra-ovarian primary peritoneal carcinoma', 'primary peritoneal serous carcinoma', 'PPC', 'primary peritoneal carcinoma (disease)', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'colorectal adenocarcinoma', 'colorectum adenocarcinoma', 'adenocarcinoma of the large bowel', 'colorectal (colon or rectal) adenocarcinoma', 'adenocarcinoma of large bowel', 'large intestine adenocarcinoma', 'adenocarcinoma of the large intestine', 'large bowel adenocarcinoma', 'adenocarcinoma of large intestine', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'liposarcoma', 'lip sarcoma', 'liposarcoma malignant', 'sarcoma of lip', 'thyroid cancer', 'neoplasm of thyroid gland', 'thyroid gland neoplasm', 'thyroid gland cancer', 'malignant tumor of the thyroid gland', 'malignant neoplasm of the thyroid gland', 'malignant thyroid tumor', 'malignant thyroid neoplasm', 'malignant neoplasm of the thyroid', 'malignant tumor of the thyroid', 'malignant tumor of thyroid', 'malignant thyroid gland neoplasm', 'cancer of thyroid gland', 'malignant thyroid gland tumour', 'malignant thyroid tumour', 'malignant tumour of thyroid', 'malignant tumour of the thyroid gland', 'malignant thyroid gland tumor', 'malignant neoplasm of thyroid gland', 'malignant tumour of thyroid gland', 'malignant tumor of thyroid gland', 'malignant tumour of the thyroid', 'malignant neoplasm of thyroid', 'macular degeneration', 'macula retinal degeneration', 'macular degeneration of retina', 'macula lutea retinal degeneration', 'retinal degeneration of macula lutea', 'colorectal neoplasm', 'colorectal tumour', 'tumor of the large bowel', 'colorectum tumour', 'large intestine tumor', 'neoplasm of colorectum', 'tumor of colorectum', 'large intestine neoplasm', 'tumor of large bowel', 'large bowel tumour', 'colorectum neoplasm (disease)', 'neoplasm of large bowel', 'large bowel tumor', 'large intestinal neoplasm', 'large intestine tumour', 'colorectum neoplasm', 'colorectum tumor', 'tumour of the large bowel', 'colorectal tumor', 'tumour of colorectum', 'tumour of large bowel', 'large bowel neoplasm', 'neoplasm of the large bowel', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'soft tissue sarcoma', 'malignant soft tissue tumor', 'malignant soft tissue tumour', 'malignant mesenchymal tumor', 'sarcoma of the soft tissue', 'soft part sarcoma', 'sarcoma of soft tissue', 'malignant mesenchymal tumour', 'connective tissue sarcoma', 'non-Rhabdo. soft tissue sarcoma', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'rhabdomyosarcoma', 'rhabdomyosarcoma malignant', 'rhabdomyosarcoma (disease)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'malignant tumour of large intestine', 'colon cancer advanced somatic', 'malignant colorectal tumor', 'malignant neoplasm of large intestine', 'malignant colorectal neoplasm', 'malignant tumour of the large intestine', 'malignant tumour of large bowel', 'malignant large intestine neoplasm', 'malignant tumor of the large intestine', 'malignant neoplasm of large bowel', 'colorectal cancer somatic', 'malignant tumour of the large bowel', 'malignant large intestine tumor', 'malignant large bowel neoplasm', 'malignant large bowel tumor', 'malignant tumor of large intestine', 'cancer of colorectum', 'malignant large bowel tumour', 'colorectal cancer with chromosomal instability somatic', 'malignant neoplasm of the large intestine', 'colon cancer somatic', 'colorectal cancer susceptibility to autosomal dominant somatic mutation', 'malignant neoplasm of colorectum', 'malignant large intestine tumour', 'malignant tumor of large bowel', 'colorectum cancer', 'malignant colorectum neoplasm', 'colorectal cancer autosomal dominant somatic mutation', 'malignant neoplasm of the large bowel', 'malignant tumor of the large bowel', 'malignant colorectal tumour', 'colon cancer susceptibility to autosomal dominant somatic mutation', 'Digestive System Carcinoma', 'gastrointestinal carcinoma (disease)', 'gastrointestinal system carcinoma', 'carcinoma of digestive system', 'digestive system carcinoma', 'gastrointestinal carcinoma', 'carcinoma of the gastrointestinal system', 'cholangiocarcinoma', 'cholangiocarcinoma malignant', 'CC', 'adult primary cholangiocellular carcinoma', 'Cholangiocellular carcinoma', 'cholangiocarcinoma intrahepatic and extrahepatic bile ducts (adenocarcinoma)', 'CCA', 'cholangiosarcoma', 'adult primary cholangiocarcinoma', 'Cholangiocar.- intra/extrahepatic', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'osteosarcoma', 'bone tissue neoplasm', 'osteogenic sarcoma', 'osteosarcoma malignant', 'OS', 'osteosarcoma (disease)', 'sarcoma of osteoid', 'osteoid sarcoma', 'colon adenocarcinoma', 'colonic adenocarcinoma', 'adenocarcinoma of colon', 'adenocarcinoma - colon', 'adenocarcinoma of the colon', 'COAD', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'Malignant Bone Neoplasm', 'osseous tumor', 'bone neoplasm', 'bone tumor', 'osseous tumour', 'bone tumour', 'malignant neoplasm of skeletal element', 'malignant bone neoplasm', 'skeletal element cancer', 'CA - bone cancer', 'cancer of skeletal element', 'malignant osseous tumour', 'malignant neoplasm of bone', 'malignant osseous neoplasm', 'malignant bone tumour', 'malignant osseous tumor', 'malignant tumor of bone', 'osseous cancer', 'cancer of bone', 'malignant skeletal element neoplasm', 'malignant tumor of the bone', 'malignant tumour of the bone', 'malignant bone tumor', 'malignant tumour of bone', 'bone cancer', 'malignant neoplasm of the bone', 'cancer of the bone', 'gastrointestinal stromal tumor', 'gastrointestinal stromal tumor familial isolated cases', 'gastrointestinal stromal sarcoma', 'gant', 'stromal tumor of gastrointestinal tract', 'gastrointestinal stromal tumor isolated cases', 'stromal tumour of gastrointestinal tract', 'gist', 'gastrointestinal stromal tumour (gist)', 'gastrointestinal stromal neoplasm', 'gastrointestinal stromal tumor (gist)', 'gastrointestinal stromal tumors', 'gastrointestinal stromal tumours', 'fallopian tube cancer', 'tumor of the fallopian tube', 'tumour of the fallopian tube', 'malignant tumour of the fallopian tube', 'malignant tumor of fallopian tubes', 'malignant tubal tumor', 'cancer of fallopian tubes', 'fallopian tube malignant neoplasm', 'tumor fallopian tube malignant', 'malignant tumour of fallopian tube', 'malignant fallopian tube neoplasm', 'fallopian tube malignant tumour', 'malignant tumor of fallopian tube', 'malignant tumor of the fallopian tube', 'malignant neoplasm of uterine tube', 'cancer of fallopian tube', 'malignant neoplasm of the fallopian tube', 'malignant tumour of fallopian tubes', 'neoplasm fallopian tube malignant', 'malignant neoplasm of fallopian tube', 'malignant fallopian tube tumor', 'tubal cancer', 'malignant fallopian tube tumour', 'fallopian tube malignant tumor', 'malignant tubal tumour', 'metastatic colorectal cancer', 'adenoid cystic carcinoma', 'cylindroid adenocarcinoma', 'adenoid cystic cancer', 'adenocystic carcinoma', 'cylindroma', 'cribriform carcinoma', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'Vascular endothelial growth factor receptor 2', 'KDR', 'FLK1', 'VEGFR2', 'CD309', 'VEGFR-2', 'FLK-1', 'VEGFR', 'Fetal liver kinase 1', 'Kinase insert domain receptor', 'Protein-tyrosine kinase receptor flk-1', 'vascular endothelial growth factor receptor 2', 'fetal liver kinase 1', 'fetal liver kinase-1', 'kinase insert domain receptor (a type III receptor tyrosine kinase)', 'protein-tyrosine kinase receptor Flk-1', 'soluble VEGFR2', 'tyrosine kinase growth factor receptor', 'kinase insert domain receptor', 'Proto-oncogene tyrosine-protein kinase receptor Ret', 'Soluble RET kinase fragment', 'Extracellular cell-membrane anchored RET cadherin 120 kDa fragment', 'RET', 'CDHF12', 'CDHR16', 'PTC', 'RET51', 'Cadherin family member 12', 'Proto-oncogene c-Ret', 'cadherin-related family member 16', 'RET receptor tyrosine kinase', 'rearranged during transfection', 'HSCR1', 'MEN2A', 'MEN2B', 'MTC1', 'RET-ELE1', 'proto-oncogene tyrosine-protein kinase receptor Ret', 'cadherin family member 12', 'proto-oncogene c-Ret', 'ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1 Hirschsprung disease)', 'ret proto-oncogene', 'Fibroblast growth factor receptor 2', 'FGFR2', 'BEK', 'KGFR', 'KSAM', 'CD332', 'FGFR-2', 'CEK3', 'TK14', 'TK25', 'ECT1', 'K-SAM', 'K-sam', 'Keratinocyte growth factor receptor', 'Crouzon syndrome', 'Pfeiffer syndrome', 'BBDS', 'BFR-1', 'CFD1', 'JWS', 'fibroblast growth factor receptor 2', 'BEK fibroblast growth factor receptor', 'bacteria-expressed kinase', 'keratinocyte growth factor receptor', 'protein tyrosine kinase receptor like 14', 'Vascular endothelial growth factor receptor 3', 'FLT4', 'VEGFR3', 'VEGFR-3', 'FLT-4', 'PCL', 'Fms-like tyrosine kinase 4', 'Tyrosine-protein kinase receptor FLT4', 'vascular endothelial growth factor receptor 3', 'VEGF receptor-3', 'Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4', 'primary congenital lymphedema', 'CHTD7', 'FLT41', 'LMPH1A', 'LMPHM1', 'fms related tyrosine kinase 4', 'fms-like tyrosine kinase 4', 'tyrosine-protein kinase receptor FLT4', 'fms related receptor tyrosine kinase 4', 'Mitogen-activated protein kinase 11', 'MAPK11', 'PRKM11', 'SAPK2', 'SAPK2B', 'MAP kinase 11', 'MAPK 11', 'MAP kinase p38 beta', 'p38b', 'SAPK2b', 'p38-2', 'p38Beta', 'Mitogen-activated protein kinase p38 beta', 'Stress-activated protein kinase 2b', 'P38B', 'P38BETA2', 'mitogen-activated protein kinase 11', 'mitogen-activated protein kinase p38 beta', 'mitogen-activated protein kinase p38-2', 'stress-activated protein kinase-2', 'stress-activated protein kinase-2b', 'Angiopoietin-1 receptor', 'TEK', 'TIE2', 'VMCM', 'VMCM1', 'CD202b', 'hTIE2', 'TIE-2', 'Endothelial tyrosine kinase', 'Tunica interna endothelial cell kinase', 'Tyrosine kinase with Ig and EGF homology domains-2', 'Tyrosine-protein kinase receptor TEK', 'Tyrosine-protein kinase receptor TIE-2', 'p140 TEK', 'angiopoietin-1 receptor', 'CD202B', 'GLC3E', 'TEK tyrosine kinase endothelial', 'endothelial tyrosine kinase', 'tunica interna endothelial cell kinase', 'tyrosine kinase with Ig and EGF homology domains-2', 'tyrosine-protein kinase receptor TEK', 'tyrosine-protein kinase receptor TIE-2', 'TEK receptor tyrosine kinase', 'Platelet-derived growth factor receptor beta', 'PDGFRB', 'PDGFR', 'PDGFR1', 'CD140b', 'PDGF-R-beta', 'PDGFR-beta', 'PDGFR-1', 'JTK12', 'Beta platelet-derived growth factor receptor', 'Beta-type platelet-derived growth factor receptor', 'CD140 antigen-like family member B', 'Platelet-derived growth factor receptor 1', 'CD140B', 'IBGC4', 'IMF1', 'KOGS', 'PENTT', 'platelet-derived growth factor receptor beta', 'Activated tyrosine kinase PDGFRB', 'NDEL1-PDGFRB', 'beta-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 1', 'platelet-derived growth factor receptor beta polypeptide', 'platelet derived growth factor receptor beta', 'Ephrin type-A receptor 2', 'EPHA2', 'ECK', 'Epithelial cell kinase', 'Tyrosine-protein kinase receptor ECK', 'ARCC2', 'CTPA', 'CTPP1', 'CTRCT6', 'ephrin type-A receptor 2', 'epithelial cell receptor protein tyrosine kinase', 'tyrosine-protein kinase receptor ECK', 'EPH receptor A2', 'Mast/stem cell growth factor receptor Kit', 'KIT', 'SCFR', 'CD117', 'PBT', 'C-Kit', 'Piebald trait protein', 'Proto-oncogene c-Kit', 'Tyrosine-protein kinase Kit', 'p145 c-kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog', 'mast/stem cell growth factor receptor Kit', 'MASTC', 'c-Kit protooncogene', 'piebald trait protein', 'proto-oncogene c-Kit', 'proto-oncogene tyrosine-protein kinase Kit', 'tyrosine-protein kinase Kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein', 'KIT proto-oncogene receptor tyrosine kinase', 'Platelet-derived growth factor receptor alpha', 'PDGFRA', 'PDGFR2', 'RHEPDGFRA', 'CD140a', 'PDGF-R-alpha', 'PDGFR-alpha', 'PDGFR-2', 'GAS9', 'Alpha platelet-derived growth factor receptor', 'Alpha-type platelet-derived growth factor receptor', 'CD140 antigen-like family member A', 'CD140a antigen', 'Platelet-derived growth factor alpha receptor', 'Platelet-derived growth factor receptor 2', 'CD140A', 'platelet-derived growth factor receptor alpha', 'alpha-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 2', 'platelet-derived growth factor receptor alpha polypeptide', 'platelet derived growth factor receptor alpha', 'Tyrosine-protein kinase ABL1', 'ABL1', 'ABL', 'JTK7', 'c-ABL', 'p150', 'Abelson murine leukemia viral oncogene homolog 1', 'Abelson tyrosine-protein kinase 1', 'Proto-oncogene c-Abl', 'BCR-ABL', 'CHDSKM', 'bcr/abl', 'c-ABL1', 'v-abl', 'tyrosine-protein kinase ABL1', 'ABL protooncogene 1 nonreceptor tyrosine kinase', 'BCR-ABL1 p190', 'BCR/ABL e8a2 fusion', 'BCR/ABL1 e1a2 fusion protein', 'bcr/c-abl oncogene protein', 'c-abl oncogene 1 receptor tyrosine kinase', 'proto-oncogene c-Abl', 'proto-oncogene tyrosine-protein kinase ABL1', 'v-abl Abelson murine leukemia viral oncogene homolog 1', 'ABL proto-oncogene 1 non-receptor tyrosine kinase', 'Vascular endothelial growth factor receptor 1', 'FLT1', 'FLT', 'FRT', 'VEGFR1', 'VEGFR-1', 'FLT-1', 'Fms-like tyrosine kinase 1', 'Tyrosine-protein kinase FRT', 'Tyrosine-protein kinase receptor FLT', 'Vascular permeability factor receptor', 'vascular endothelial growth factor receptor 1', 'vascular permeability factor receptor', 'fms related tyrosine kinase 1', 'fms-like tyrosine kinase 1', 'fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)', 'tyrosine-protein kinase FRT', 'tyrosine-protein kinase receptor FLT', 'fms related receptor tyrosine kinase 1', 'Fibroblast growth factor receptor 1', 'FGFR1', 'BFGFR', 'CEK', 'FGFBR', 'FLG', 'FLT2', 'HBGFR', 'CD331', 'FGFR-1', 'bFGF-R-1', 'FLT-2', 'H2', 'H3', 'H4', 'H5', 'N-SAM', 'Basic fibroblast growth factor receptor 1', 'Fms-like tyrosine kinase 2', 'N-sam', 'Proto-oncogene c-Fgr', 'ECCL', 'HH2', 'HRTFDS', 'KAL2', 'OGD', 'fibroblast growth factor receptor 1', 'FGFR1/PLAG1 fusion', 'FMS-like tyrosine kinase 2', 'basic fibroblast growth factor receptor 1', 'fms-related tyrosine kinase 2', 'heparin-binding growth factor receptor', 'hydroxyaryl-protein kinase', 'proto-oncogene c-Fgr', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'Tyrosine-protein kinase FRK', 'FRK', 'PTK5', 'RAK', 'GTK', 'FYN-related kinase', 'Nuclear tyrosine protein kinase RAK', 'Protein-tyrosine kinase 5', 'tyrosine-protein kinase FRK', 'PTK5 protein tyrosine kinase 5', 'fyn-related kinase', 'nuclear tyrosine protein kinase RAK', 'protein-tyrosine kinase 5', 'fyn related Src family tyrosine kinase', 'Discoidin domain-containing receptor 2', 'DDR2', 'NTRKR3', 'TKT', 'TYRO10', 'CD167b', 'Discoidin domain receptor 2', 'CD167 antigen-like family member B', 'Discoidin domain-containing receptor tyrosine kinase 2', 'Neurotrophic tyrosine kinase receptor-related 3', 'Receptor protein-tyrosine kinase TKT', 'Tyrosine-protein kinase TYRO10', 'MIG20a', 'WRCN', 'discoidin domain-containing receptor 2', 'cell migration-inducing protein 20', 'discoidin domain receptor 2', 'discoidin domain receptor family member 2', 'discoidin domain-containing receptor tyrosine kinase 2', 'migration-inducing gene 16 protein', 'neurotrophic tyrosine kinase receptor related 3', 'receptor protein-tyrosine kinase TKT', 'tyrosine-protein kinase TYRO10', 'discoidin domain receptor tyrosine kinase 2', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'High affinity nerve growth factor receptor', 'NTRK1', 'MTC', 'TRK', 'TRKA', 'Trk-A', 'Neurotrophic tyrosine kinase receptor type 1', 'TRK1-transforming tyrosine kinase protein', 'Tropomyosin-related kinase A', 'Tyrosine kinase receptor', 'Tyrosine kinase receptor A', 'gp140trk', 'p140-TrkA', 'high affinity nerve growth factor receptor', 'tropomyosin receptor kinase A', 'TRK1', 'Oncogene TRK', 'neurotrophic tyrosine kinase receptor type 1', 'tropomyosin-related kinase A', 'tyrosine kinase receptor A', 'neurotrophic receptor tyrosine kinase 1', 'carcinoma', 'endocrine system disease', 'cancer or benign tumor', 'gastrointestinal disease', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'pancreas disease', 'reproductive system or breast disease', 'cardiovascular disease', 'nervous system disease', 'urinary system disease', 'integumentary system disease', 'musculoskeletal or connective tissue disease', 'disorder of visual system', 'hematologic disease', 'immune system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2012 and has 6 approved and 30 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0000616', 'EFO_0000365', 'MONDO_0004992', 'EFO_0004142', 'MONDO_0005575', 'EFO_1001951']",pharmgkb,toxicity,decreased risk of drug toxicity,,rs4864950,TRUE
CHEMBL1946170,RAF1,CAND2,LVEF,"",United States,REGORAFENIB,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['biliary tract cancer', 'cancer of biliary tree', 'biliary tree cancer', 'malignant tumour of biliary tract', 'malignant neoplasm of biliary tree', 'malignant tumor of biliary tract', 'malignant biliary tree neoplasm', 'small cell lung carcinoma', 'SCLC', 'oat cell carcinoma', 'oat cell carcinoma (morphologic abnormality)', 'poorly differentiated endocrine neoplasm', 'oat cell carcinoma of the lung', 'oat cell carcinoma of lung', 'small cell neuroendocrine carcinoma of lung', 'lung small cell neuroendocrine carcinoma', 'lung oat cell carcinoma', 'oat cell lung carcinoma', 'small cell cancer of the lung somatic', 'small cell carcinoma of lung', 'small cell neuroendocrine carcinoma of the lung', 'lung small cell carcinoma', 'small cell lung cancer', 'small-cell cancer of lung', 'small cell carcinoma of the lung', 'SCLC1', 'small cell cancer of the lung', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'malignant colon neoplasm', 'malignant tumour of the colon', 'malignant colonic tumour', 'malignant neoplasm of the colon', 'malignant colon tumour', 'malignant colon tumor', 'colon neoplasm malignant', 'cancer of colon', 'malignant tumour of colon', 'malignant tumor of the colon', 'malignant colonic neoplasm', 'colon cancer', 'malignant neoplasm of colon', 'malignant tumor of colon', 'malignant colonic tumor', 'colon tumor malignant', 'rectum cancer', 'carcinoma of the rectum', 'carcinoma of rectum', 'malignant rectal tumour', 'malignant rectum tumor', 'malignant neoplasm of rectum', 'malignant rectal neoplasm', 'malignant neoplasm of the rectum', 'rectal cancer', 'malignant tumor of the rectum', 'malignant tumour of the rectum', 'malignant rectum tumour', 'cancer of rectum', 'malignant rectum neoplasm', 'malignant tumour of rectum', 'malignant tumor of rectum', 'malignant rectal tumor', 'ovarian neoplasm', 'OVARY NEOPL', 'Ovary Neoplasm', 'ovarian tumour', 'ovary neoplasm (disease)', 'Neoplasm Ovary', 'Cancer of Ovary', 'ovarian tumors', 'neoplasm of ovary', 'ovary tumor', 'Neoplasms Ovary', 'tumour of the ovary', 'neoplasm of the ovary', 'Ovary Neoplasms', 'ovarian tumours', 'tumor of ovary', 'ovarian tumor', 'Neoplasm Ovarian', 'tumour of ovary', 'Neoplasms Ovarian', 'OVARIAN NEOPL', 'NEOPL OVARIAN', 'ovary tumour', 'tumor of the ovary', 'Ovarian Neoplasms', 'ovary neoplasm', 'angiosarcoma', 'vascular sarcoma', 'hemangiosarcoma malignant', 'sarcoma of blood vessel', 'malignant hemangioendothelioma', 'hemangiosarcoma', 'blood vessel sarcoma', 'angiosarcoma (disease)', 'malignant angioendothelioma', 'glioblastoma multiforme', 'grade IV adult astrocytic tumor', 'glioblastoma multiforme (disease)', 'grade IV astrocytic tumor', 'glioblastoma', 'glioblastoma (disease)', 'grade IV astrocytic neoplasm', 'GBM', 'spongioblastoma multiforme', 'grade IV astrocytoma', 'WHO grade IV glioma', 'GBM (glioblastoma)', 'primary glioblastoma multiforme', 'grade IV astrocytic tumour', 'grade IV adult astrocytic tumour', 'giant cell glioblastoma (histologic variant)', 'gliosarcoma (histologic variant)', 'intrahepatic cholangiocarcinoma', 'peripheral cholangiocarcinoma', 'cholangiocarcinoma intrahepatic malignant', 'intrahepatic Cholangiocellular carcinoma', 'intrahepatic bile duct cancer (cholangiocarcinoma)', 'intrahepatic carcinoma of the bile duct', 'intrahepatic carcinoma of bile duct', 'intrahepatic bile duct carcinoma', 'ICC', 'intrahepatic cholangiocarcinoma (bile duct cancer)', 'IHCH', 'malignant renal pelvis neoplasm', 'malignant tumour of renal pelvis', 'malignant renal pelvis tumor', 'malignant tumour of the renal pelvis', 'malignant tumor of the renal pelvis', 'malignant tumor of renal pelvis', 'malignant renal pelvis tumour', 'renal pelvis cancer', 'malignant neoplasm of renal pelvis', 'malignant neoplasm of the renal pelvis', 'cancer of renal pelvis', 'ovarian carcinoma', 'ovarian cancer', 'ovarian epithelial cancer', 'carcinoma of ovary', 'ovary carcinoma', 'EOS', 'epithelial ovarian cancer', 'carcinoma of the ovary', 'pancreatic adenocarcinoma', 'adenocarcinoma - pancreas', 'pancreas adenocarcinoma', 'adenocarcinoma of pancreas', 'adenocarcinoma of the pancreas', 'PAAD', 'bile duct carcinoma', 'bile duct cancer', 'bile duct cancer (including cholangiocarcinoma)', 'carcinoma of bile duct', 'gastric cancer', 'gastric neoplasm', 'malignant tumor of lesser curve of stomach', 'malignant tumour of body of stomach', 'malignant neoplasm of stomach', 'gastric cancer risk after h. pylori infection', 'malignant neoplasm of lesser curve of stomach', 'malignant gastric tumour', 'malignant gastric neoplasm', 'malignant tumour of greater curve of stomach', 'Ca lesser curvature - stomach', 'malignant stomach neoplasm', 'malignant tumor of greater curve of stomach', 'malignant tumor of body of stomach', 'malignant tumour of the stomach', 'malignant tumour of stomach', 'malignant tumor of the stomach', 'gastric cancer somatic', 'malignant tumour of lesser curve of stomach', 'malignant neoplasm of the stomach', 'malignant tumor of stomach', 'cancer of stomach', 'malignant gastric tumor', 'stomach cancer', 'Ca body - stomach', 'ca greater curvature of stomach', 'malignant neoplasm of body of stomach', 'gastric cancer intestinal', 'primary peritoneal carcinoma', 'EOPPC', 'serous surface papillary carcinoma', 'primary peritoneal cancer', 'Extra-ovarian primary peritoneal carcinoma', 'primary peritoneal serous carcinoma', 'PPC', 'primary peritoneal carcinoma (disease)', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'colorectal adenocarcinoma', 'colorectum adenocarcinoma', 'adenocarcinoma of the large bowel', 'colorectal (colon or rectal) adenocarcinoma', 'adenocarcinoma of large bowel', 'large intestine adenocarcinoma', 'adenocarcinoma of the large intestine', 'large bowel adenocarcinoma', 'adenocarcinoma of large intestine', 'cutaneous melanoma', 'zone of skin melanoma', 'malignant neck melanoma', 'cutaneous melanoma (disease)', 'malignant scalp melanoma', 'malignant upper limb melanoma', 'malignant melanoma of skin of upper limb', 'malignant ear melanoma', 'melanoma of skin', 'malignant melanoma of skin of lower limb', 'zone of skin melanoma (disease)', 'melanoma (disease) of zone of skin', 'malignant melanoma of skin of trunk except scrotum', 'skin melanoma', 'malignant lower limb melanoma', 'malignant trunk melanoma', 'malignant melanoma of skin', 'malignant cutaneous melanoma', 'malignant melanoma of ear and/or external auricular canal', 'cutaneous (skin) melanoma', 'malignant lip melanoma', 'malignant melanoma of skin stage unspecified', 'malignant melanoma (of skin) stage unspecified', 'melanoma of the skin', 'liposarcoma', 'lip sarcoma', 'liposarcoma malignant', 'sarcoma of lip', 'thyroid cancer', 'neoplasm of thyroid gland', 'thyroid gland neoplasm', 'thyroid gland cancer', 'malignant tumor of the thyroid gland', 'malignant neoplasm of the thyroid gland', 'malignant thyroid tumor', 'malignant thyroid neoplasm', 'malignant neoplasm of the thyroid', 'malignant tumor of the thyroid', 'malignant tumor of thyroid', 'malignant thyroid gland neoplasm', 'cancer of thyroid gland', 'malignant thyroid gland tumour', 'malignant thyroid tumour', 'malignant tumour of thyroid', 'malignant tumour of the thyroid gland', 'malignant thyroid gland tumor', 'malignant neoplasm of thyroid gland', 'malignant tumour of thyroid gland', 'malignant tumor of thyroid gland', 'malignant tumour of the thyroid', 'malignant neoplasm of thyroid', 'macular degeneration', 'macula retinal degeneration', 'macular degeneration of retina', 'macula lutea retinal degeneration', 'retinal degeneration of macula lutea', 'colorectal neoplasm', 'colorectal tumour', 'tumor of the large bowel', 'colorectum tumour', 'large intestine tumor', 'neoplasm of colorectum', 'tumor of colorectum', 'large intestine neoplasm', 'tumor of large bowel', 'large bowel tumour', 'colorectum neoplasm (disease)', 'neoplasm of large bowel', 'large bowel tumor', 'large intestinal neoplasm', 'large intestine tumour', 'colorectum neoplasm', 'colorectum tumor', 'tumour of the large bowel', 'colorectal tumor', 'tumour of colorectum', 'tumour of large bowel', 'large bowel neoplasm', 'neoplasm of the large bowel', 'acute myeloid leukemia', 'acute myelogenous leukemia', 'AML', 'hematopoeitic - acute Myleogenous leukaemia (AML)', 'acute Nonlymphocytic leukemia', 'myeloid leukemia acute', 'leukemia acute myeloid somatic', 'acute myeloid leukemia (AML)', 'acute granulocytic leukemia', 'acute nonlymphocytic leukemia', 'acute granulocytic leukaemia', 'acute myelogenous leukaemia', 'ANLL', 'leukemia myelocytic acute', 'myeloid leukemia acute M4/M4Eo subtype somatic', 'AML - acute myeloid leukemia', 'hematopoeitic - acute Myleogenous leukemia (AML)', 'acute myeloid leukaemia (AML)', 'acute myeloblastic leukemia', 'AML - acute myeloid leukaemia', 'acute Nonlymphocytic leukaemia', 'acute myelocytic leukaemia', 'acute myeloid leukemia somatic', 'leukemia acute myeloid autosomal dominant somatic mutation', 'acute myelocytic leukemia', 'acute myeloblastic leukaemia', 'leukemia acute myeloid reduced survival in somatic', 'leukemia acute myeloid susceptibility to autosomal dominant somatic mutation', 'acute myelogenous leukemias', 'acute nonlymphocytic leukaemia', 'acute non lymphoblastic leukaemia', 'leukemia acute myeloid susceptibility to', 'leukemia acute myeloid', 'acute non lymphoblastic leukemia', 'leukemia acute myelogenous', 'soft tissue sarcoma', 'malignant soft tissue tumor', 'malignant soft tissue tumour', 'malignant mesenchymal tumor', 'sarcoma of the soft tissue', 'soft part sarcoma', 'sarcoma of soft tissue', 'malignant mesenchymal tumour', 'connective tissue sarcoma', 'non-Rhabdo. soft tissue sarcoma', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'rhabdomyosarcoma', 'rhabdomyosarcoma malignant', 'rhabdomyosarcoma (disease)', 'sarcoma', 'tumor of soft tissue and skeleton', 'sarcoma malignant', 'sarcoma of the soft tissue and bone', 'mesenchymal tumor malignant', 'sarcoma of soft tissue and bone', 'tumour of soft tissue and skeleton', 'malignant tumour of large intestine', 'colon cancer advanced somatic', 'malignant colorectal tumor', 'malignant neoplasm of large intestine', 'malignant colorectal neoplasm', 'malignant tumour of the large intestine', 'malignant tumour of large bowel', 'malignant large intestine neoplasm', 'malignant tumor of the large intestine', 'malignant neoplasm of large bowel', 'colorectal cancer somatic', 'malignant tumour of the large bowel', 'malignant large intestine tumor', 'malignant large bowel neoplasm', 'malignant large bowel tumor', 'malignant tumor of large intestine', 'cancer of colorectum', 'malignant large bowel tumour', 'colorectal cancer with chromosomal instability somatic', 'malignant neoplasm of the large intestine', 'colon cancer somatic', 'colorectal cancer susceptibility to autosomal dominant somatic mutation', 'malignant neoplasm of colorectum', 'malignant large intestine tumour', 'malignant tumor of large bowel', 'colorectum cancer', 'malignant colorectum neoplasm', 'colorectal cancer autosomal dominant somatic mutation', 'malignant neoplasm of the large bowel', 'malignant tumor of the large bowel', 'malignant colorectal tumour', 'colon cancer susceptibility to autosomal dominant somatic mutation', 'Digestive System Carcinoma', 'gastrointestinal carcinoma (disease)', 'gastrointestinal system carcinoma', 'carcinoma of digestive system', 'digestive system carcinoma', 'gastrointestinal carcinoma', 'carcinoma of the gastrointestinal system', 'cholangiocarcinoma', 'cholangiocarcinoma malignant', 'CC', 'adult primary cholangiocellular carcinoma', 'Cholangiocellular carcinoma', 'cholangiocarcinoma intrahepatic and extrahepatic bile ducts (adenocarcinoma)', 'CCA', 'cholangiosarcoma', 'adult primary cholangiocarcinoma', 'Cholangiocar.- intra/extrahepatic', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'osteosarcoma', 'bone tissue neoplasm', 'osteogenic sarcoma', 'osteosarcoma malignant', 'OS', 'osteosarcoma (disease)', 'sarcoma of osteoid', 'osteoid sarcoma', 'colon adenocarcinoma', 'colonic adenocarcinoma', 'adenocarcinoma of colon', 'adenocarcinoma - colon', 'adenocarcinoma of the colon', 'COAD', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'Malignant Bone Neoplasm', 'osseous tumor', 'bone neoplasm', 'bone tumor', 'osseous tumour', 'bone tumour', 'malignant neoplasm of skeletal element', 'malignant bone neoplasm', 'skeletal element cancer', 'CA - bone cancer', 'cancer of skeletal element', 'malignant osseous tumour', 'malignant neoplasm of bone', 'malignant osseous neoplasm', 'malignant bone tumour', 'malignant osseous tumor', 'malignant tumor of bone', 'osseous cancer', 'cancer of bone', 'malignant skeletal element neoplasm', 'malignant tumor of the bone', 'malignant tumour of the bone', 'malignant bone tumor', 'malignant tumour of bone', 'bone cancer', 'malignant neoplasm of the bone', 'cancer of the bone', 'gastrointestinal stromal tumor', 'gastrointestinal stromal tumor familial isolated cases', 'gastrointestinal stromal sarcoma', 'gant', 'stromal tumor of gastrointestinal tract', 'gastrointestinal stromal tumor isolated cases', 'stromal tumour of gastrointestinal tract', 'gist', 'gastrointestinal stromal tumour (gist)', 'gastrointestinal stromal neoplasm', 'gastrointestinal stromal tumor (gist)', 'gastrointestinal stromal tumors', 'gastrointestinal stromal tumours', 'fallopian tube cancer', 'tumor of the fallopian tube', 'tumour of the fallopian tube', 'malignant tumour of the fallopian tube', 'malignant tumor of fallopian tubes', 'malignant tubal tumor', 'cancer of fallopian tubes', 'fallopian tube malignant neoplasm', 'tumor fallopian tube malignant', 'malignant tumour of fallopian tube', 'malignant fallopian tube neoplasm', 'fallopian tube malignant tumour', 'malignant tumor of fallopian tube', 'malignant tumor of the fallopian tube', 'malignant neoplasm of uterine tube', 'cancer of fallopian tube', 'malignant neoplasm of the fallopian tube', 'malignant tumour of fallopian tubes', 'neoplasm fallopian tube malignant', 'malignant neoplasm of fallopian tube', 'malignant fallopian tube tumor', 'tubal cancer', 'malignant fallopian tube tumour', 'fallopian tube malignant tumor', 'malignant tubal tumour', 'metastatic colorectal cancer', 'adenoid cystic carcinoma', 'cylindroid adenocarcinoma', 'adenoid cystic cancer', 'adenocystic carcinoma', 'cylindroma', 'cribriform carcinoma', 'renal cell carcinoma', 'RCC', 'renal cell carcinoma (disease)', 'kidney adenocarcinoma', 'hypernephroma', 'renal cell adenocarcinoma', 'Vascular endothelial growth factor receptor 2', 'KDR', 'FLK1', 'VEGFR2', 'CD309', 'VEGFR-2', 'FLK-1', 'VEGFR', 'Fetal liver kinase 1', 'Kinase insert domain receptor', 'Protein-tyrosine kinase receptor flk-1', 'vascular endothelial growth factor receptor 2', 'fetal liver kinase 1', 'fetal liver kinase-1', 'kinase insert domain receptor (a type III receptor tyrosine kinase)', 'protein-tyrosine kinase receptor Flk-1', 'soluble VEGFR2', 'tyrosine kinase growth factor receptor', 'kinase insert domain receptor', 'Proto-oncogene tyrosine-protein kinase receptor Ret', 'Soluble RET kinase fragment', 'Extracellular cell-membrane anchored RET cadherin 120 kDa fragment', 'RET', 'CDHF12', 'CDHR16', 'PTC', 'RET51', 'Cadherin family member 12', 'Proto-oncogene c-Ret', 'cadherin-related family member 16', 'RET receptor tyrosine kinase', 'rearranged during transfection', 'HSCR1', 'MEN2A', 'MEN2B', 'MTC1', 'RET-ELE1', 'proto-oncogene tyrosine-protein kinase receptor Ret', 'cadherin family member 12', 'proto-oncogene c-Ret', 'ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1 Hirschsprung disease)', 'ret proto-oncogene', 'Fibroblast growth factor receptor 2', 'FGFR2', 'BEK', 'KGFR', 'KSAM', 'CD332', 'FGFR-2', 'CEK3', 'TK14', 'TK25', 'ECT1', 'K-SAM', 'K-sam', 'Keratinocyte growth factor receptor', 'Crouzon syndrome', 'Pfeiffer syndrome', 'BBDS', 'BFR-1', 'CFD1', 'JWS', 'fibroblast growth factor receptor 2', 'BEK fibroblast growth factor receptor', 'bacteria-expressed kinase', 'keratinocyte growth factor receptor', 'protein tyrosine kinase receptor like 14', 'Vascular endothelial growth factor receptor 3', 'FLT4', 'VEGFR3', 'VEGFR-3', 'FLT-4', 'PCL', 'Fms-like tyrosine kinase 4', 'Tyrosine-protein kinase receptor FLT4', 'vascular endothelial growth factor receptor 3', 'VEGF receptor-3', 'Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4', 'primary congenital lymphedema', 'CHTD7', 'FLT41', 'LMPH1A', 'LMPHM1', 'fms related tyrosine kinase 4', 'fms-like tyrosine kinase 4', 'tyrosine-protein kinase receptor FLT4', 'fms related receptor tyrosine kinase 4', 'Mitogen-activated protein kinase 11', 'MAPK11', 'PRKM11', 'SAPK2', 'SAPK2B', 'MAP kinase 11', 'MAPK 11', 'MAP kinase p38 beta', 'p38b', 'SAPK2b', 'p38-2', 'p38Beta', 'Mitogen-activated protein kinase p38 beta', 'Stress-activated protein kinase 2b', 'P38B', 'P38BETA2', 'mitogen-activated protein kinase 11', 'mitogen-activated protein kinase p38 beta', 'mitogen-activated protein kinase p38-2', 'stress-activated protein kinase-2', 'stress-activated protein kinase-2b', 'Angiopoietin-1 receptor', 'TEK', 'TIE2', 'VMCM', 'VMCM1', 'CD202b', 'hTIE2', 'TIE-2', 'Endothelial tyrosine kinase', 'Tunica interna endothelial cell kinase', 'Tyrosine kinase with Ig and EGF homology domains-2', 'Tyrosine-protein kinase receptor TEK', 'Tyrosine-protein kinase receptor TIE-2', 'p140 TEK', 'angiopoietin-1 receptor', 'CD202B', 'GLC3E', 'TEK tyrosine kinase endothelial', 'endothelial tyrosine kinase', 'tunica interna endothelial cell kinase', 'tyrosine kinase with Ig and EGF homology domains-2', 'tyrosine-protein kinase receptor TEK', 'tyrosine-protein kinase receptor TIE-2', 'TEK receptor tyrosine kinase', 'Platelet-derived growth factor receptor beta', 'PDGFRB', 'PDGFR', 'PDGFR1', 'CD140b', 'PDGF-R-beta', 'PDGFR-beta', 'PDGFR-1', 'JTK12', 'Beta platelet-derived growth factor receptor', 'Beta-type platelet-derived growth factor receptor', 'CD140 antigen-like family member B', 'Platelet-derived growth factor receptor 1', 'CD140B', 'IBGC4', 'IMF1', 'KOGS', 'PENTT', 'platelet-derived growth factor receptor beta', 'Activated tyrosine kinase PDGFRB', 'NDEL1-PDGFRB', 'beta-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 1', 'platelet-derived growth factor receptor beta polypeptide', 'platelet derived growth factor receptor beta', 'Ephrin type-A receptor 2', 'EPHA2', 'ECK', 'Epithelial cell kinase', 'Tyrosine-protein kinase receptor ECK', 'ARCC2', 'CTPA', 'CTPP1', 'CTRCT6', 'ephrin type-A receptor 2', 'epithelial cell receptor protein tyrosine kinase', 'tyrosine-protein kinase receptor ECK', 'EPH receptor A2', 'Mast/stem cell growth factor receptor Kit', 'KIT', 'SCFR', 'CD117', 'PBT', 'C-Kit', 'Piebald trait protein', 'Proto-oncogene c-Kit', 'Tyrosine-protein kinase Kit', 'p145 c-kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog', 'mast/stem cell growth factor receptor Kit', 'MASTC', 'c-Kit protooncogene', 'piebald trait protein', 'proto-oncogene c-Kit', 'proto-oncogene tyrosine-protein kinase Kit', 'tyrosine-protein kinase Kit', 'v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein', 'KIT proto-oncogene receptor tyrosine kinase', 'Platelet-derived growth factor receptor alpha', 'PDGFRA', 'PDGFR2', 'RHEPDGFRA', 'CD140a', 'PDGF-R-alpha', 'PDGFR-alpha', 'PDGFR-2', 'GAS9', 'Alpha platelet-derived growth factor receptor', 'Alpha-type platelet-derived growth factor receptor', 'CD140 antigen-like family member A', 'CD140a antigen', 'Platelet-derived growth factor alpha receptor', 'Platelet-derived growth factor receptor 2', 'CD140A', 'platelet-derived growth factor receptor alpha', 'alpha-type platelet-derived growth factor receptor', 'platelet-derived growth factor receptor 2', 'platelet-derived growth factor receptor alpha polypeptide', 'platelet derived growth factor receptor alpha', 'Tyrosine-protein kinase ABL1', 'ABL1', 'ABL', 'JTK7', 'c-ABL', 'p150', 'Abelson murine leukemia viral oncogene homolog 1', 'Abelson tyrosine-protein kinase 1', 'Proto-oncogene c-Abl', 'BCR-ABL', 'CHDSKM', 'bcr/abl', 'c-ABL1', 'v-abl', 'tyrosine-protein kinase ABL1', 'ABL protooncogene 1 nonreceptor tyrosine kinase', 'BCR-ABL1 p190', 'BCR/ABL e8a2 fusion', 'BCR/ABL1 e1a2 fusion protein', 'bcr/c-abl oncogene protein', 'c-abl oncogene 1 receptor tyrosine kinase', 'proto-oncogene c-Abl', 'proto-oncogene tyrosine-protein kinase ABL1', 'v-abl Abelson murine leukemia viral oncogene homolog 1', 'ABL proto-oncogene 1 non-receptor tyrosine kinase', 'Vascular endothelial growth factor receptor 1', 'FLT1', 'FLT', 'FRT', 'VEGFR1', 'VEGFR-1', 'FLT-1', 'Fms-like tyrosine kinase 1', 'Tyrosine-protein kinase FRT', 'Tyrosine-protein kinase receptor FLT', 'Vascular permeability factor receptor', 'vascular endothelial growth factor receptor 1', 'vascular permeability factor receptor', 'fms related tyrosine kinase 1', 'fms-like tyrosine kinase 1', 'fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)', 'tyrosine-protein kinase FRT', 'tyrosine-protein kinase receptor FLT', 'fms related receptor tyrosine kinase 1', 'Fibroblast growth factor receptor 1', 'FGFR1', 'BFGFR', 'CEK', 'FGFBR', 'FLG', 'FLT2', 'HBGFR', 'CD331', 'FGFR-1', 'bFGF-R-1', 'FLT-2', 'H2', 'H3', 'H4', 'H5', 'N-SAM', 'Basic fibroblast growth factor receptor 1', 'Fms-like tyrosine kinase 2', 'N-sam', 'Proto-oncogene c-Fgr', 'ECCL', 'HH2', 'HRTFDS', 'KAL2', 'OGD', 'fibroblast growth factor receptor 1', 'FGFR1/PLAG1 fusion', 'FMS-like tyrosine kinase 2', 'basic fibroblast growth factor receptor 1', 'fms-related tyrosine kinase 2', 'heparin-binding growth factor receptor', 'hydroxyaryl-protein kinase', 'proto-oncogene c-Fgr', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'Tyrosine-protein kinase FRK', 'FRK', 'PTK5', 'RAK', 'GTK', 'FYN-related kinase', 'Nuclear tyrosine protein kinase RAK', 'Protein-tyrosine kinase 5', 'tyrosine-protein kinase FRK', 'PTK5 protein tyrosine kinase 5', 'fyn-related kinase', 'nuclear tyrosine protein kinase RAK', 'protein-tyrosine kinase 5', 'fyn related Src family tyrosine kinase', 'Discoidin domain-containing receptor 2', 'DDR2', 'NTRKR3', 'TKT', 'TYRO10', 'CD167b', 'Discoidin domain receptor 2', 'CD167 antigen-like family member B', 'Discoidin domain-containing receptor tyrosine kinase 2', 'Neurotrophic tyrosine kinase receptor-related 3', 'Receptor protein-tyrosine kinase TKT', 'Tyrosine-protein kinase TYRO10', 'MIG20a', 'WRCN', 'discoidin domain-containing receptor 2', 'cell migration-inducing protein 20', 'discoidin domain receptor 2', 'discoidin domain receptor family member 2', 'discoidin domain-containing receptor tyrosine kinase 2', 'migration-inducing gene 16 protein', 'neurotrophic tyrosine kinase receptor related 3', 'receptor protein-tyrosine kinase TKT', 'tyrosine-protein kinase TYRO10', 'discoidin domain receptor tyrosine kinase 2', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'High affinity nerve growth factor receptor', 'NTRK1', 'MTC', 'TRK', 'TRKA', 'Trk-A', 'Neurotrophic tyrosine kinase receptor type 1', 'TRK1-transforming tyrosine kinase protein', 'Tropomyosin-related kinase A', 'Tyrosine kinase receptor', 'Tyrosine kinase receptor A', 'gp140trk', 'p140-TrkA', 'high affinity nerve growth factor receptor', 'tropomyosin receptor kinase A', 'TRK1', 'Oncogene TRK', 'neurotrophic tyrosine kinase receptor type 1', 'tropomyosin-related kinase A', 'tyrosine kinase receptor A', 'neurotrophic receptor tyrosine kinase 1', 'carcinoma', 'endocrine system disease', 'cancer or benign tumor', 'gastrointestinal disease', 'genetic familial or congenital disease', 'respiratory or thoracic disease', 'pancreas disease', 'reproductive system or breast disease', 'cardiovascular disease', 'nervous system disease', 'urinary system disease', 'integumentary system disease', 'musculoskeletal or connective tissue disease', 'disorder of visual system', 'hematologic disease', 'immune system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 2012 and has 6 approved and 30 investigational indications. This drug has a black box warning from the FDA.,"['EFO_0000616', 'EFO_0000365', 'MONDO_0004992', 'EFO_0004142', 'MONDO_0005575', 'EFO_1001951']",pharmgkb,toxicity,increased risk of drug toxicity,,rs4864950,TRUE
CHEMBL3348923,RAF1,CAND2,LVEF,"","",TOVORAFENIB,No,INHIBITOR,RAF serine/threonine protein kinase inhibitor,"['Craniopharyngioma', 'Rathke pouch tumor', """"""""Rathke's pouch tumor"""""""", 'craniopharyngioma', """"""""Rathke's pouch neoplasm"""""""", 'craniopharyngioma (morphologic abnormality)', 'Rathke pouch neoplasm', """"""""Rathke's pouch tumour"""""""", 'cystoma', 'craniopharyngioma benign', """"""""tumour of Rathke's pouch"""""""", 'Rathke pouch tumour', """"""""tumor of Rathke's pouch"""""""", 'craniopharyngioma (WHO grade I)', """"""""neoplasm of Rathke's pouch"""""""", 'Adamantinomatous tumour', 'Dysodontogenic epithelial tumor', 'Dysodontogenic epithelial tumour', 'craniopharyngeal duct tumour', 'craniopharyngeal duct tumor', 'Adamantinomatous tumor', 'low grade glioma', 'low-grade glioma', 'metastatic melanoma', 'metastatic malignant melanoma', 'papillary thyroid carcinoma', 'papillary cancer of the thyroid gland', 'papillary carcinoma of the thyroid', 'thyroid gland papillary carcinoma', 'papillary carcinoma of thyroid', 'papillary carcinoma of the thyroid gland', 'PTC', 'papillary thyroid cancer', 'papillary cancer of the thyroid', 'thyroid gland papillary cancer', 'papillary thyroid gland carcinoma', 'papillary carcinoma of thyroid gland', 'thyroid papillary carcinoma', 'papillary cancer of thyroid gland', 'papillary cancer of thyroid', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'Spindle Cell Melanoma', 'malignant spindle cell melanoma', 'spitzoid malignant melanoma', 'spindle cell malignant melanoma', 'spindle cell melanoma', 'desmoplastic melanoma', 'pancreatic carcinoma', 'exocrine cancer', 'cancer of pancreas', 'pancreatic cancer', 'pancreas cancer', 'cancer of the pancreas', 'pancreas carcinoma', 'exocrine pancreas carcinoma', 'carcinoma of pancreas', 'carcinoma of the pancreas', 'exocrine pancreatic carcinoma', 'pancreatic cancer (not islets)', 'carcinoma of exocrine pancreas', 'pancreatic carcinoma familial', 'pilocytic astrocytoma', 'grade I astrocytoma', 'grade I astrocytic tumor', 'Piloid astrocytoma', 'grade I astrocytic neoplasm', 'grade I astrocytic tumour', 'astrocytoma benign', 'astrocytoma pilocytic benign', 'Langerhans Cell Histiocytosis', 'letterer-Siwe disease of lymph nodes of inguinal region amd/or lower limb', 'letterer-Siwe disease of intrathoracic lymph nodes', 'letterer-Siwe disease of lymph nodes of inguinal region and lower limb', 'letterer-Siwe disease of lymph nodes of axilla and upper limb', 'letterer-Siwe disease involving intrathoracic lymph nodes', 'letterer-Siwe disease of lymph nodes of axilla and/or upper limb', 'letterer-Siwe disease involving intrapelvic lymph nodes', 'letterer-Siwe disease involving lymph nodes of head face and neck', 'Langerhans cell histiocytosis', 'histiocytosis X', 'letterer-Siwe disease of intra-abdominal lymph nodes', 'Langerhans cell granulomatosis', 'letterer-Siwe disease involving spleen', 'letterer-Siwe disease of lymph nodes of multiple sites', 'letterer-Siwe disease of lymph nodes of head face and/or neck', 'letterer-Siwe disease of intrapelvic lymph nodes', 'Langerhans cell histiocytosis Not otherwise specified', 'letterer-Siwe disease of spleen', 'letterer-Siwe disease involving lymph nodes of inguinal region and lower limb', 'letterer-Siwe disease of lymph nodes of inguinal region and/or lower limb', 'letterer-Siwe disease of lymph nodes of head face and neck', 'LCH', 'letterer-Siwe disease involving lymph nodes of axilla and upper limb', """"""""Langerhan's cell histiocytosis"""""""", 'letterer-Siwe disease involving intra-abdominal lymph nodes', 'letterer-Siwe disease involving lymph nodes of multiple sites', 'Langerhans cell histiocytosis NOS', 'Langerhans-cell histiocytosis', 'Lch', 'bladder transitional cell carcinoma', 'urinary bladder transitional cell carcinoma', 'bladder urothelial cancer', 'urothelial carcinoma of the urinary bladder', 'transitional cell carcinoma of the urinary bladder', 'bladder urothelial carcinoma', 'transitional cell carcinoma of bladder', 'urothelial bladder carcinoma', 'urinary bladder urothelial carcinoma', 'BLCA', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'Serine/threonine-protein kinase A-Raf', 'ARAF', 'ARAF1', 'PKS', 'PKS2', 'A-Raf', 'Proto-oncogene A-Raf', 'Proto-oncogene A-Raf-1', 'Proto-oncogene Pks', 'A-RAF', 'RAFA1', 'serine/threonine-protein kinase A-Raf', 'A-Raf proto-oncogene serine/threonine-protein kinase', 'Oncogene ARAF1', 'Ras-binding protein DA-Raf', 'proto-oncogene A-Raf-1', 'proto-oncogene Pks', 'v-raf murine sarcoma 3611 viral oncogene homolog 1', 'v-raf murine sarcoma 3611 viral oncogene-like protein', 'A-Raf proto-oncogene serine/threonine kinase', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'musculoskeletal or connective tissue disease', 'cancer or benign tumor', 'nervous system disease', 'endocrine system disease', 'gastrointestinal disease', 'pancreas disease', 'hematologic disease', 'genetic familial or congenital disease', 'immune system disease', 'urinary system disease', 'respiratory or thoracic disease']",protein family,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 5 investigational indications.,[],"","","",,"",
CHEMBL3545027,RAF1,CAND2,LVEF,"","",XL-281,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'papillary thyroid carcinoma', 'papillary cancer of the thyroid gland', 'papillary carcinoma of the thyroid', 'thyroid gland papillary carcinoma', 'papillary carcinoma of thyroid', 'papillary carcinoma of the thyroid gland', 'PTC', 'papillary thyroid cancer', 'papillary cancer of the thyroid', 'thyroid gland papillary cancer', 'papillary thyroid gland carcinoma', 'papillary carcinoma of thyroid gland', 'thyroid papillary carcinoma', 'papillary cancer of thyroid gland', 'papillary cancer of thyroid', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'cancer or benign tumor', 'gastrointestinal disease', 'endocrine system disease', 'respiratory or thoracic disease']",single protein,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 4 investigational indications.,[],"","","",,"",
CHEMBL3545082,RAF1,CAND2,LVEF,"","",RG-7376,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,[],single protein,Small molecule drug with a maximum clinical trial phase of I.,"","","","",,"",
CHEMBL3545195,RAF1,CAND2,LVEF,"","",LY-3009120,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'metastasis', 'tumor metastasis', 'tumor cell migration', 'cancer metastasis', 'neoplasm metastasis', 'colorectal neoplasm', 'colorectal tumour', 'tumor of the large bowel', 'colorectum tumour', 'large intestine tumor', 'neoplasm of colorectum', 'tumor of colorectum', 'large intestine neoplasm', 'tumor of large bowel', 'large bowel tumour', 'colorectum neoplasm (disease)', 'neoplasm of large bowel', 'large bowel tumor', 'large intestinal neoplasm', 'large intestine tumour', 'colorectum neoplasm', 'colorectum tumor', 'tumour of the large bowel', 'colorectal tumor', 'tumour of colorectum', 'tumour of large bowel', 'large bowel neoplasm', 'neoplasm of the large bowel', 'non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'Serine/threonine-protein kinase A-Raf', 'ARAF', 'ARAF1', 'PKS', 'PKS2', 'A-Raf', 'Proto-oncogene A-Raf', 'Proto-oncogene A-Raf-1', 'Proto-oncogene Pks', 'A-RAF', 'RAFA1', 'serine/threonine-protein kinase A-Raf', 'A-Raf proto-oncogene serine/threonine-protein kinase', 'Oncogene ARAF1', 'Ras-binding protein DA-Raf', 'proto-oncogene A-Raf-1', 'proto-oncogene Pks', 'v-raf murine sarcoma 3611 viral oncogene homolog 1', 'v-raf murine sarcoma 3611 viral oncogene-like protein', 'A-Raf proto-oncogene serine/threonine kinase', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'cancer or benign tumor', 'biological_process', 'gastrointestinal disease', 'respiratory or thoracic disease']",single protein,Small molecule drug with a maximum clinical trial phase of I (across all indications) and has 4 investigational indications.,[],"","","",,"",
CHEMBL3545263,RAF1,CAND2,LVEF,"","",LGX-806,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,[],single protein,Small molecule drug with a maximum clinical trial phase of I.,"","","","",,"",
CHEMBL3545296,RAF1,CAND2,LVEF,"","",ARQ-736,No,INHIBITOR,Serine/threonine-protein kinase RAF inhibitor,"['neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'cancer or benign tumor']",single protein,Small molecule drug with a maximum clinical trial phase of I and has 1 investigational indication.,[],"","","",,"",
CHEMBL3977543,RAF1,CAND2,LVEF,"","",BELVARAFENIB,No,INHIBITOR,RAF serine/threonine protein kinase inhibitor,"['melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'Serine/threonine-protein kinase A-Raf', 'ARAF', 'ARAF1', 'PKS', 'PKS2', 'A-Raf', 'Proto-oncogene A-Raf', 'Proto-oncogene A-Raf-1', 'Proto-oncogene Pks', 'A-RAF', 'RAFA1', 'serine/threonine-protein kinase A-Raf', 'A-Raf proto-oncogene serine/threonine-protein kinase', 'Oncogene ARAF1', 'Ras-binding protein DA-Raf', 'proto-oncogene A-Raf-1', 'proto-oncogene Pks', 'v-raf murine sarcoma 3611 viral oncogene homolog 1', 'v-raf murine sarcoma 3611 viral oncogene-like protein', 'A-Raf proto-oncogene serine/threonine kinase', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'cancer or benign tumor']",protein family,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 3 investigational indications.,[],"","","",,"",
CHEMBL4583691,RAF1,CAND2,LVEF,"","",LXH254,No,INHIBITOR,B-raf/RAF proto-oncogene serine/threonine-protein kinase inhibitor,"['non-small cell lung carcinoma', 'non-small cell lung carcinoma (disease)', 'non-small cell carcinoma of lung', 'non-small cell carcinoma of the lung', 'NSCLC - non-small cell lung cancer', 'non-small cell lung cancer', 'NSCLC', 'non-small cell cancer of the lung', 'non-small cell cancer of lung', 'melanoma', 'melanoma (disease)', 'melanoma malignant', 'malignant melanoma', 'Naevocarcinoma', 'Serine/threonine-protein kinase B-raf', 'BRAF', 'BRAF1', 'RAFB1', 'BRAF-1', 'Proto-oncogene B-Raf', 'p94', 'v-Raf murine sarcoma viral oncogene homolog B1', 'B-RAF1', 'B-raf', 'NS7', 'serine/threonine-protein kinase B-raf', '94 kDa B-raf protein', 'B-Raf proto-oncogene serine/threonine-protein kinase (p94)', 'B-Raf serine/threonine-protein', 'murine sarcoma viral (v-raf) oncogene homolog B1', 'proto-oncogene B-Raf', 'v-raf murine sarcoma viral oncogene homolog B', 'v-raf murine sarcoma viral oncogene homolog B1', 'B-Raf proto-oncogene serine/threonine kinase', 'RAF proto-oncogene serine/threonine-protein kinase', 'RAF1', 'RAF', 'cRaf', 'Raf-1', 'c-Raf', 'CRAF', 'Proto-oncogene c-RAF', 'C-Raf proto-oncogene serine/threonine kinase', 'CMD1NN', 'NS5', 'Oncogene RAF1', 'proto-oncogene c-RAF', 'raf proto-oncogene serine/threonine protein kinase', 'v-raf-1 murine leukemia viral oncogene homolog 1', 'v-raf-1 murine leukemia viral oncogene-like protein 1', 'Raf-1 proto-oncogene serine/threonine kinase', 'respiratory or thoracic disease', 'cancer or benign tumor']",protein family,Small molecule drug with a maximum clinical trial phase of II (across all indications) and has 2 investigational indications.,[],"","","",,"",
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192176,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs279858,TRUE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922876,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192163,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922803,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922764,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922876,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs3813867,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192161,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922772,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922764,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922762,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs2307116,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922809,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918594,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922753,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs112563513,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192124,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922753,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922802,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922747,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs1801086,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192122,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918595,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192162,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs2307116,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922843,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased likelihood of adverse events and improved response to sevoflurane and remifentanil,,rs1128503,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192170,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922843,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918596,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,decreased vol% end-tidal sevoflurane concentration,,rs3733784,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192176,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922809,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922762,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922816,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192177,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192167,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922802,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922747,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922803,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs63749869,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs144336148,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918592,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922772,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918592,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922748,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs1801394,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,worse response to sevoflurane and remifentanil,,rs1128503,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192168,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs111888148,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs2031920,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192163,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,decreased vol% end-tidal sevoflurane concentration,,rs1801394,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,increased sedation,,rs6686529,TRUE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs1806201,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922770,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs118192167,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192116,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,increased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933397,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,increased likelihood of adverse events,,rs1128503,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918594,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs1275988,TRUE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,worse response to sevoflurane and remifentanil,,rs1128503,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs28933396,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922818,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,decreased likelihood of adverse events and improved response to sevoflurane and remifentanil,,rs1128503,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918596,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,decreased vol% end-tidal sevoflurane concentration,,rs2307116,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922818,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192172,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,increased vol% end-tidal sevoflurane concentration,,rs1801394,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs1801394,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918593,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192168,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs2031920,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918593,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192172,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs112563513,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192124,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,develop malignant hyperthermia,,rs193922878,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,increased likelihood of adverse events,,rs1128503,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918595,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192178,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,increased vol% end-tidal sevoflurane concentration,,rs3733784,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192175,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs111888148,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,increased vol% end-tidal sevoflurane concentration,,rs2307116,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922807,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs1806201,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922832,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922807,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192122,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,efficacy,decreased sedation,,rs6686529,TRUE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,increased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192177,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs279858,TRUE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs28933397,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192161,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922878,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922770,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922748,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922816,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922768,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1801086,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922878,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192175,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,greater severity of hypotension,,rs1042718,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,increased mean arterial pressure,,rs3813867,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,other,decreased mean arterial pressure,,rs1275988,TRUE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933396,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922768,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922832,FALSE
CHEMBL1200694,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",SEVOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['intelligence', 'cognitive ability', 'general cognitive function', 'general cognitive ability', 'morbid obesity', 'Severe obesity', 'Obesities Morbid', 'Morbid obesity (disorder)', 'severe obesity', 'Obesity Morbid', 'Morbid Obesities', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'Laryngospasm', 'inflammation', 'inflammatory response', 'drug dependence', 'Habituation Drug', 'Usage Drug', 'Abuse Drug', 'Disorder Drug Use', 'Dependence Drug', 'DRUG USE DIS', 'Drug Use Disorder', 'Drug Habituation', 'Drug Usage', 'Drug Abuse', 'Addiction Drug', 'Drug Use Disorders', 'Drug Addiction', 'chemical dependence', 'hypertension', 'HTN', 'pressure high blood', 'High Blood Pressure', '[X]Hypertensive diseases', 'increased blood pressure', 'HYPERTENSIVE DISEASE', '(hypertensive disease) or (hypertension)', 'vascular hypertensive disorder', 'hypertensive disorder', 'hypertension NOS', 'Hypertensive disease NOS (disorder)', 'hyperpiesia', '[X]Hypertensive diseases (disorder)', 'blood pressure increased', 'High blood pressure (& [essential hypertension])', 'HTN - hypertension', 'blood pressure high', 'Hypertensive disease (disorder)', 'hypertensive disease NOS', 'Blood Pressures High', 'SURG COMP - HYPERTENSION', 'hypertensive disease', 'High Blood Pressures', 'high blood pressure', 'Blood Pressure High', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'kidney cancer', 'malignant neoplasm of the kidney', 'malignant kidney tumor', 'malignant neoplasm of kidney except pelvis', 'malignant kidney tumour', 'malignant tumor of kidney', 'malignant neoplasm of kidney', 'malignant tumor of the kidney', 'malignant renal tumour', 'malignant tumour of kidney', 'malignant tumour of the kidney', 'malignant renal tumor', 'malignant renal neoplasm', 'malignant kidney neoplasm', 'cancer of kidney', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'hemorrhage', 'bleeding', 'haemorrhage', 'female breast carcinoma', 'carcinoma of female breast', 'breast carcinoma female', 'female breast cancer', 'mammary carcinoma of the female breast', 'mammary carcinoma of female breast', 'carcinoma of the female breast', 'bone fracture', 'fracture(s)', 'Bones Broken', 'Fractures Bone', 'Bone Fractures', 'Broken Bone', 'Bone Broken', 'fracture of bone', 'Broken Bones', 'fracture', 'Fracture Bone', 'infection', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'brain injury', 'injury of brain', 'brain trauma', 'brain Traumas', 'sinusitis', 'fluoride poisoning', 'fluoride toxicity', 'Back pain', 'ovarian cancer', 'tumour of the ovary', 'ovarian neoplasm', 'ovary neoplasm', 'tumor of the ovary', 'malignant tumor of the ovary', 'malignant ovarian neoplasm', 'malignant ovarian tumor', 'cancer of ovary', 'malignant tumor of ovary', 'malignant neoplasm of ovary', 'ovary cancer', 'malignant tumour of ovary', 'malignant ovarian tumour', 'ovarian malignant tumor', 'malignant tumour of the ovary', 'cancer of the ovary', 'ovarian malignant tumour', 'malignant neoplasm of the ovary', 'malignant ovary neoplasm', 'ovarian cancer somatic', 'ovarian cancer epithelial', 'primary ovarian cancer', 'internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'colorectal carcinoma', 'large bowel cancer', 'large intestine cancer', 'cancer of the large bowel', 'colorectal cancer', 'cancer of large intestine', 'cancer of large bowel', 'cancer of the large intestine', 'colorectal (colon or rectal) cancer', 'large intestine carcinoma', 'CRC', 'carcinoma of large bowel', 'large bowel carcinoma', 'carcinoma of colorectum', 'carcinoma of the large intestine', 'colorectum carcinoma', 'carcinoma of large intestine', 'carcinoma of the large bowel', 'congenital heart disease', 'heart malformation', 'congenital heart defects', 'congenital heart defect', 'congenital anomaly of heart', 'heart defect', 'heart defect congenital', 'heart-congenital defect', 'defect congenital heart', 'heart abnormalities', 'heart malformation Of', 'Abnormality heart', 'defects congenital heart', 'abnormalities heart', 'heart abnormality', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'lung neoplasm', 'lung tumor', 'neoplasm of lung', 'tumor of lung', 'lung neoplasm (disease)', 'tumour of the lung', 'tumour of lung', 'lung tumour', 'tumor of the lung', 'neoplasm of the lung', 'lung neoplasms', 'neoplasm lung', 'lung', 'neoplasm pulmonary', 'neoplasms pulmonary', 'neoplasms lung', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'neurotoxicity', 'aneurysm', 'oxidative stress', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'hepatocellular carcinoma', 'liver and intrahepatic bile duct carcinoma', 'liver cell cancer (hepatocellular carcinoma)', 'carcinoma of liver cells', 'hepatocellular adenocarcinoma', 'liver cell carcinoma', 'HCC', 'primary carcinoma of liver cells', 'carcinoma of the liver cells', 'hepatocellular carcinoma somatic', 'hepatoma', 'hepatocellular cancer', 'liver carcinoma', 'hepatocellular carcinoma childhood type somatic', 'hepatoblastoma somatic', 'cancer hepatocellular', 'hepatocellular cancer somatic', 'primary carcinoma of the liver cells', 'carcinoma hepatocellular malignant', 'carcinoma of liver', 'adult primary hepatocellular carcinoma', 'adult hepatoma', 'liver cancer', 'hepatoblastoma', 'hepatoblastoma caused by somatic mutation', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'brain neoplasm', 'Intracranial Neoplasms', 'Recurrent Brain Tumor', 'Tumor Brain', 'Recurrent Brain Tumors', 'Neoplasms Brain', 'PRIMARY BRAIN NEOPL', 'Brain Tumor Recurrent', 'Brain Tumors', 'Neoplasm Brain', 'Brain Neoplasms', 'Brain Tumor', 'tumour of brain', 'Intracranial Neoplasm', 'NEOPL BRAIN', 'Tumors Brain', 'tumor of the Brain', 'brain neoplasms', 'INTRACRANIAL NEOPL', 'tumor of brain', 'Neoplasms Intracranial', 'neoplasm of brain', 'neoplasm of the brain', 'brain neoplasm (disease)', 'Neoplasm Intracranial', 'Brain Tumors Recurrent', 'NEOPL INTRACRANIAL', 'tumour of the Brain', 'brain tumor', 'brain tumour', 'septic shock', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'neoplasm', 'cell process disease', 'neoplasm (disease)', 'tumor', 'disease of cellular proliferation', 'neoplastic disease', 'neoplastic growth', 'tumor disease', 'tumour disease', 'tumour', 'neoplasia', 'other neoplasm', 'breast cancer', 'breast tumor', 'mammary tumour', 'mammary tumor', 'breast tumour', 'mammary cancer', 'malignant tumor of breast', 'malignant neoplasm of the breast', 'malignant breast tumor', 'BC', 'cancer of breast', 'malignant tumour of breast', 'malignant neoplasm of breast', 'malignant tumor of the breast', 'malignant breast neoplasm', 'malignant tumour of the breast', 'malignant breast tumour', 'primary breast cancer', 'mammary neoplasm', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'depressive disorder', 'depression', 'mental depression', 'melancholia', 'syndromes depressive', 'melancholias', 'syndrome depressive', 'post-operative sign or symptom', 'acute myocardial infarction', 'myocardial infarction (disease) acute', 'AMI', 'acute myocardial infarction (disease)', 'severe acute respiratory syndrome', 'SARS-CoV infection', 'SARS-associated coronavirus', 'SARS coronavirus disease or disorder', 'acute respiratory coronavirus infection', 'SARS coronavirus infectious disease', 'Respiratory Syndrome Acute Severe', 'SARS ASSOC CORONAVIRUS', 'SARS coronavirus caused disease or disorder', 'Respiratory Syndrome Severe Acute', 'SARS', 'Severe acute respiratory syndrome (disorder)', 'myocardial infarction', 'Cardiac infarction', 'MI MYOCARDIAL INFARCTION', 'Myocardial Infarctions', 'Myocardial infarction NOS', 'Cardiac infarction NOS', 'MYOCARDIAL INFARCTION (MI)', 'Infarcts Myocardial', 'Myocardial Infarct', 'infarction (MI) myocardial', 'Infarction Myocardial', 'MI', 'Infarctions Myocardial', 'INFARCTION (MI) MYOCARDIAL', 'Infarction of heart', 'myocardial infarct', 'Infarction of heart NOS', 'Myocardial Infarcts', 'Heart attack NOS', 'heart attack', 'myocardial infarction (MI)', 'Myocardial infarction (disorder)', 'MI - Myocardial infarction', 'Attack - heart', 'myocardial infarction (disease)', 'MI myocardial infarction', 'Infarct Myocardial', 'Acute kidney injury', 'Acute kidney failure', 'Acute renal failure', 'acute respiratory distress syndrome', 'shock lung', 'ARDS', 'Shock lung', 'acute lung injury', 'non-cardiogenic pulmonary edema', 'non-cardiogenic pulmonary oedema', 'increased-permeability pulmonary oedema', 'ALI', 'Stiff lung', 'increased-permeability pulmonary edema', 'carcinoma', 'epithelioma', 'Other carcinoma', 'malignant epithelioma', 'epithelioma malignant', 'epithelial carcinoma', 'malignant epithelial neoplasm', 'malignant epithelial tumor', 'carcinoma malignant', 'malignant epithelial tumour', 'energy expenditure', 'Recurrent tonsillitis', 'Recurrent inflammation of tonsils', 'Agitation', 'Psychomotor agitation', 'memory impairment', 'Memory Impairment Adverse Event', 'female reproductive system disease', 'disease of female reproductive system', 'female reproductive system disease or disorder', 'disorder of female reproductive system', 'female reproductive disease', 'disease or disorder of female reproductive system', 'female reproductive system disorder', 'disorder of female genital system', 'disease of female genital system', 'gynecological disease', 'gynaecological disease', 'disorder of female genital tract', 'retinopathy', 'retinal disorder', 'retinal disease', 'retina eye disease', 'eye disease of retina', 'lung cancer', 'malignant neoplasm of lung', 'malignant lung tumour', 'malignant tumour of the lung', 'malignant lung neoplasm', 'lung cancer somatic', 'nonsmall cell lung cancer somatic', 'malignant tumor of the lung', 'lung cancer protection against autosomal dominant somatic mutation', 'malignant tumor of lung', 'malignant tumour of lung', 'lung cancer susceptibility to autosomal dominant somatic mutation', 'malignant lung tumor', 'nonsmall cell lung cancer susceptibility to autosomal dominant somatic mutation', 'cancer of lung', 'malignant neoplasm of the lung', 'adenocarcinoma of lung response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'lung cancer resistance to autosomal dominant somatic mutation', 'nonsmall cell lung cancer response to tyrosine kinase inhibitor in autosomal dominant somatic mutation', 'adenocarcinoma of lung somatic', 'lung cancer protection against', 'alveolar cell carcinoma', 'Nonsmall cell lung cancer', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'dental phobia', 'dental fear', 'dentist phobia', 'dentophobia', 'dental anxiety', 'odontophobia', 'Cough', 'Coughing', 'alcohol-related disorders', 'alcohol related disorders', 'alcohol-related disorder', 'disorder alcohol-related', 'disorders alcohol-related', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'brain aneurysm', 'Cerebral Aneurysms', 'Aneurysm Intracranial Mycotic', 'Aneurysms Giant Intracranial', 'Aneurysm Cerebral', 'Anterior Communicating Artery Aneurysm', 'Berry Aneurysms', 'Cerebral Aneurysm', 'Aneurysms Intracranial Mycotic', 'Mycotic Aneurysm Intracranial', 'Aneurysm Basilar Artery', 'Intracranial Mycotic Aneurysms', 'Aneurysms Berry', 'Middle Cerebral Artery Aneurysm', 'Aneurysm Anterior Communicating Artery', 'Anterior Cerebral Artery Aneurysm', 'Intracranial Aneurysms', 'Aneurysms Brain', 'Berry Aneurysm', 'Intracranial Aneurysms Giant', 'Aneurysm Intracranial', 'Basilar Artery Aneurysm', 'Artery Aneurysm Basilar', 'Artery Aneurysms Basilar', 'Mycotic Aneurysms Intracranial', 'Aneurysms Basilar Artery', 'Posterior Communicating Artery Aneurysm', 'Aneurysm Middle Cerebral Artery', 'Aneurysm Brain', 'Intracranial Aneurysm Giant', 'Brain Aneurysms', 'Aneurysm Posterior Cerebral Artery', 'Aneurysm Posterior Communicating Artery', 'Aneurysm Giant Intracranial', 'Giant Intracranial Aneurysm', 'Aneurysm Anterior Cerebral Artery', 'Aneurysm Berry', 'Giant Intracranial Aneurysms', 'Basilar Artery Aneurysms', 'Intracranial Mycotic Aneurysm', 'Aneurysms Intracranial', 'Intracranial Aneurysm', 'Aneurysms Cerebral', 'Posterior Cerebral Artery Aneurysm', 'intracranial aneurysm', 'Pituitary Gland Adenoma', 'adenoma of pituitary', 'pituitary gland adenoma', 'pituitary adenoma', 'adenoma of the pituitary gland', 'adenoma of the pituitary', 'adenoma of pituitary gland', 'adenoma anterior lobe pituitary gland benign', 'PTAD', 'esophageal cancer', 'esophageal squamous cell carcinoma somatic', 'malignant oesophagus tumour', 'malignant esophagus tumor', 'malignant tumour of oesophagus', 'malignant neoplasm of the oesophagus', 'malignant neoplasm of the esophagus', 'oesophagus cancer', 'cancer of oesophagus', 'malignant esophagus neoplasm', 'malignant esophageal neoplasm', 'esophagus cancer', 'malignant tumor of the esophagus', 'malignant neoplasm of esophagus', 'malignant neoplasm of oesophagus', 'cancer of esophagus', 'esophageal carcinoma somatic', 'malignant esophageal tumour', 'malignant oesophagus neoplasm', 'malignant tumor of esophagus', 'malignant esophageal tumor', 'esophageal cancer somatic', 'malignant tumour of the oesophagus', 'malignant neoplasm of upper third esophagus', 'malignant neoplasm of distal third of oesophagus', 'malignant tumor of the middle third of the esophagus', 'malignant tumor of distal third of esophagus', 'Ca lower third oesophagus', 'Ca middle third oesophagus', 'malignant tumor of proximal third of esophagus', 'malignant neoplasm of distal third of esophagus', 'malignant tumour of the middle third of the oesophagus', 'malignant neoplasm of proximal third of esophagus', 'malignant tumour of distal third of oesophagus', 'malignant tumor of abdominal esophagus', 'Ca lower third esophagus', 'malignant tumour of abdominal oesophagus', 'malignant neoplasm of lower third of oesophagus', 'Ca middle third esophagus', 'malignant neoplasm of middle third of oesophagus', 'malignant neoplasm of middle third of esophagus', 'malignant tumour of proximal third of oesophagus', 'malignant neoplasm of lower third of esophagus', 'malignant neoplasm of upper third oesophagus', 'malignant neoplasm of proximal third of oesophagus', 'gastric cardia adenocarcinoma susceptibility to', 'esophageal squamous cell carcinoma susceptibility to', 'Escc susceptibility to', 'Aerodigestive tract cancer susceptibility to', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'cancer', 'organ system cancer', 'neoplasm malignant', 'malignant tumor', 'malignant neoplastic disease', 'malignant neoplasm (disease)', 'malignant neoplasm', 'malignant Growth', 'malignancy', 'neoplasm (disease) malignant', 'CA', 'cell type cancer', 'malignant tumour', 'primary cancer', 'MT', 'pain', 'Sufferings Physical', 'Pains Radiating', 'Crushing Pain', 'Radiating Pains', 'Pains Crushing', 'Splitting Pains', 'Migratory Pain', 'Burning Pain', 'Ache', 'Suffering Physical', 'Crushing Pains', 'Pain Migratory', 'Pains Migratory', 'Pain Radiating', 'Aches', 'Radiating Pain', 'Burning Pains', 'Physical Sufferings', 'Pain Splitting', 'Pains Burning', 'Splitting Pain', 'Pains Splitting', 'Migratory Pains', 'Physical Suffering', 'Pain Crushing', 'Pain Burning', 'Skin ulcer', 'Open skin sore', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'biological_process', 'nutritional or metabolic disease', 'cardiovascular disease', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'urinary system disease', 'cancer or benign tumor', 'integumentary system disease', 'reproductive system or breast disease', 'musculoskeletal or connective tissue disease', 'injury poisoning or other complication', 'respiratory or thoracic disease', 'endocrine system disease', 'gastrointestinal disease', 'genetic familial or congenital disease', 'infectious disease', 'disorder of visual system']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1995 and has 32 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192162,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922753,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922818,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192162,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192161,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922762,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192124,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922803,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192168,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922747,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933396,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918593,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192122,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922818,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922876,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192176,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922803,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192178,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs1801086,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918594,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192116,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922816,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192163,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192167,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918596,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922762,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192175,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918592,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922748,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs111888148,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922770,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs28933396,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922843,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918594,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922876,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922878,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922832,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192124,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922802,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs144336148,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs118192167,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922753,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922807,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192122,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933397,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922768,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192161,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918595,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs63749869,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192170,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,develop malignant hyperthermia,,rs193922878,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922832,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs112563513,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs28933397,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922772,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192172,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922816,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922878,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192177,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922748,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922807,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192172,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922809,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192177,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192176,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922768,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1801086,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918595,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192163,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922764,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,increased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs111888148,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918596,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918593,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192175,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192168,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922809,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918592,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922770,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922764,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922747,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs112563513,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922802,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922843,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922772,FALSE
CHEMBL1200733,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DESFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['internal carotid artery stenosis', 'Internal carotid artery stenosis (disorder)', 'ICA - Internal carotid artery stenosis', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'chronic kidney disease', 'END STAGE RENAL DIS', 'Renal Insufficiency Chronic', 'END STAGE KIDNEY DIS', 'chronic renal insufficiency', 'End-Stage Renal Failure', 'chronic renal disease', 'renal failure - chronic', 'Renal Insufficiencies Chronic', 'Chronic Kidney Insufficiency', 'CKD - chronic kidney disease', 'End Stage Renal Disease', 'Chronic Kidney Insufficiencies', 'RENAL DIS END STAGE', 'End-Stage Kidney Disease', 'End-Stage Renal Disease', 'Kidney Failure Chronic', 'Renal Disease End-Stage', 'Kidney Insufficiency Chronic', 'Renal Failure End Stage', 'Disease End-Stage Renal', 'Chronic Renal Insufficiencies', 'Disease End-Stage Kidney', 'Renal Failure Chronic', 'Renal Disease End Stage', 'Renal Failure End-Stage', 'ESRD', 'Kidney Disease End-Stage', 'kidney disease chronic', 'CKD', 'End Stage Kidney Disease', 'chronic kidney failure', 'Kidney Insufficiencies Chronic', 'Chronic Renal Failure', 'chronic renal failure syndrome', 'rotator cuff tear', 'rotator cuff syndrome', 'rotator cuff injury', 'Agitation', 'Psychomotor agitation', 'osteoarthritis', 'hypertrophic arthritis', 'degenerative joint disease', 'degenerative arthritis', 'osteoarthrosis and allied disorder', 'osteoarthrosis', 'oxidative stress', 'post operative nausea and vomiting', 'Postoperative Nausea and Vomiting', 'avascular necrosis', 'AVN', 'avascular necrosis of bone', 'sudden cardiac arrest', 'sudden cardiac death', 'death sudden cardiac', 'post-operative sign or symptom', 'obesity', 'Overweight and obesity', 'obesity disease', 'Obesity [Ambiguous]', 'Obesity unspecified', 'Obesity NOS', 'Obesity (disorder)', 'Obese (finding)', 'obesity disorder', 'Obese', 'Adiposity', 'Adiposis', 'End Stage Liver Disease', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'aortic stenosis', 'Stenoses Aortic Valve', 'Stenosis Aortic', 'AS', 'Aortic Valve Stenosis', 'AS - Aortic stenosis', 'Aortic Valve Stenoses', 'Stenosed aortic valve', 'Aortic valve stenosis NOS', 'Stenoses Aortic', 'Valve Stenosis Aortic', 'Aortic valve stenosis (disorder)', 'Valve Stenoses Aortic', 'Stenosis Aortic Valve', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'cardiovascular disease', 'nervous system disease', 'psychiatric disorder', 'urinary system disease', 'musculoskeletal or connective tissue disease', 'phenotype', 'biological_process', 'nutritional or metabolic disease', 'endocrine system disease', 'gastrointestinal disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1992 and has 2 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192162,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922770,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192116,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918595,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192122,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922816,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922802,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922878,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918596,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs144336148,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192175,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192177,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922770,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192176,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs112563513,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922753,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192175,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922818,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922772,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922876,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922802,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs1801086,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs112563513,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs118192167,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922748,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192163,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922762,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922876,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192178,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192162,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs28933397,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922762,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922832,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918595,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922807,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918593,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192161,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192172,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs28933396,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192167,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192176,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922878,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918592,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922747,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs63749869,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs111888148,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192163,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922768,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922809,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192124,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1801086,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922764,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918593,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,develop malignant hyperthermia,,rs193922878,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922843,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192168,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922818,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922803,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922772,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192177,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922843,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922753,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192122,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918596,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192172,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933397,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192162,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs118192168,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192170,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922764,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922768,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs121918594,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922747,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922816,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs193922807,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,malignant hyperthermia,,rs111888148,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933396,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922809,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918594,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918592,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922832,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922748,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922803,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192161,FALSE
CHEMBL1256,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ISOFLURANE,Yes,OPENER,Potassium channel subfamily K member 3 opener,"['Inguinal hernia', 'toxicity', 'heart disease', 'Cardiac Diseases', 'heart/pericardial disease', 'Disease Heart', 'cardiac disease', 'heart disease or disorder', 'heart/pericardial disorder', 'Disease Cardiac', 'heart trouble', 'Heart Diseases', 'disorder of heart', 'heart disorder', 'Diseases Heart', 'heart/pericardial disease or disorder', 'disorder of heart/pericardium', 'Cardiac Disease', 'disease or disorder of heart', 'heart/pericardial trouble', 'disease of heart', 'Diseases Cardiac', 'CARDIAC DIS', 'HEART DIS', 'breast neoplasm', 'Tumor Breast', 'BREAST NEOPL', 'Mammary Neoplasm Human', 'Mammary Neoplasms Human', 'tumour of the breast', 'neoplasm of breast', 'NEOPL BREAST', 'Human Mammary Neoplasms', 'Breast Tumor', 'Breast Tumors', 'tumor of breast', 'breast tumor', 'neoplasm of the breast', 'tumor of the breast', 'Neoplasms Breast', 'Breast Neoplasms', 'Tumors Breast', 'breast tumour', 'Neoplasms Human Mammary', 'neoplasm breast', 'Neoplasm Human Mammary', 'Human Mammary Neoplasm', 'tumour of breast', 'breast neoplasm (disease)', 'Neoplasm Breast', 'delirium', 'organic brain syndrome', 'OBS syndrome', 'subarachnoid hemorrhage', 'Intracranial Subarachnoid Hemorrhage', 'SAH - Subarachnoid haemorrhage', 'Hemorrhages Perinatal Subarachnoid', 'SAH - Subarachnoid hemorrhage', 'Hemorrhage Subarachnoid', 'Subarachnoid Hemorrhage Aneurysmal', 'Subarachnoid haemorrhage NOS', 'Hemorrhage Spontaneous Subarachnoid', 'Hemorrhages Aneurysmal Subarachnoid', 'SAHs (Subarachnoid Hemorrhage)', 'Perinatal Subarachnoid Hemorrhage', 'Aneurysmal Subarachnoid Hemorrhages', 'subarachnoid hemorrhage (disease)', 'Hemorrhage Intracranial Subarachnoid', 'Subarachnoid Hemorrhages Spontaneous', 'Hemorrhages Spontaneous Subarachnoid', 'Aneurysmal Subarachnoid Hemorrhage', 'Subarachnoid Hemorrhage Perinatal', 'Intracranial Subarachnoid Hemorrhages', 'Hemorrhages Intracranial Subarachnoid', 'Subarachnoid Hemorrhages', 'Spontaneous Subarachnoid Hemorrhages', 'Hemorrhage Aneurysmal Subarachnoid', 'Spontaneous Subarachnoid Hemorrhage', 'Subarachnoid aneurysmal hemorrhage', 'Hemorrhages Subarachnoid', 'Subarachnoid Hemorrhage Spontaneous', 'SAH (Subarachnoid Hemorrhage)', 'Subarachnoid hemorrhage NOS (disorder)', 'Perinatal Subarachnoid Hemorrhages', 'Subarachnoid Hemorrhages Perinatal', 'subarachnoid haemorrhage (disease)', 'Subarachnoid hemorrhage (disorder)', 'Subarachnoid Hemorrhage Intracranial', 'Subarachnoid haemorrhage', 'SAH', 'Hemorrhage Perinatal Subarachnoid', 'Subarachnoid hemorrhage NOS', 'Subarachnoid Hemorrhages Intracranial', 'Subarachnoid Hemorrhages Aneurysmal', 'Myocardial Ischemia', 'ischaemic heart disease', 'myocardium ischemic disease', 'ischemic disease of myocardium', 'ischaemic disease of myocardium', 'myocardial ischemia', 'myocardium ischaemic disease', 'ischemic heart disease', 'IHD', 'heart diseases ischaemic', 'ischemic heart diseases', 'heart disease ischemic', 'heart diseases ischemic', 'myocardial Ischemias', 'disease ischemic heart', 'disease ischaemic heart', 'diseases ischemic heart', 'diseases ischaemic heart', 'heart disease ischaemic', 'ischemias myocardial', 'ischaemic heart diseases', 'ischemia myocardial', 'septic shock', 'respiratory failure', 'respiratory insufficiency/failure', 'failure respiratory', 'chronic respiratory failure', 'acute respiratory failure', 'acute-on-chronic respiratory failure', 'acute and chronic respiratory failure', 'ischemia reperfusion injury', 'ischaemia reperfusion injury', 'myocardial reperfusion injury', 'opioid dependence', 'Opioid-Related Disorders', 'opiate abuse', 'opiate dependence', 'opioid type dependence', 'opiate addiction', 'opioid abuse', 'narcotism', 'kidney failure', 'renal insufficiency', 'renal failure', 'renal failure syndrome', 'failure renal', 'hypotension', 'low blood pressure', 'hypotensive disorder', 'hypotension (disease)', 'coronary artery disease', 'Coronary Arteriosclerosis', 'Disease Coronary', 'Diseases Coronary', 'Arterioscleroses Coronary', 'coronary heart disease', 'Disease Coronary Heart', 'CHD - Coronary heart disease', 'Atherosclerosis Coronary', 'Arteriosclerosis Coronary', 'Coronary Atheroscleroses', 'CORONARY ARTERY DIS', 'Atheroscleroses Coronary', 'CHD (coronary heart disease)', 'coronary artery disorder', 'Diseases Coronary Heart', 'CORONARY HEART DIS', 'Artery Disease Coronary', 'Disease Coronary Artery', 'Heart Disease Coronary', 'CORONARY DIS', 'CHD', 'Coronary Artery Diseases', 'disease of coronary artery', 'Heart Diseases Coronary', 'Coronary Disease', 'coronary artery disease or disorder', 'Coronary Heart Diseases', 'Artery Diseases Coronary', 'disease or disorder of coronary artery', 'coronary disease', 'Coronary Diseases', 'Coronary Artery Disease', 'Coronary Arterioscleroses', 'Diseases Coronary Artery', 'Coronary Atherosclerosis', 'disorder of coronary artery', 'CAD', 'coronary arteriosclerosis', 'intracranial subdural hematoma', 'subdural intracranial hematoma', 'intracranial hematoma subdural', 'subdural hematoma', 'Hematoma Subdural Intracranial', 'COVID-19', 'severe acute respiratory syndrome coronavirus 2 infectious disease', 'CoV-2 infection', 'coronavirus disease 2019', '2019 novel coronavirus infection', '2019-nCoV infection', '2019 novel coronavirus', 'β-CoV', 'beta-CoV', 'SARS-CoV-2', 'β-CoVs', '2019-nCoV', 'betacoronavirus', 'β-coronavirus', 'severe acute respiratory syndrome coronavirus 2', 'SARS-coronavirus 2', 'beta-CoVs', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Gamma-aminobutyric acid receptor subunit alpha-4', 'GABRA4', 'GABA(A) receptor subunit alpha-4', 'GABA(A) receptor alpha 4', 'gamma-aminobutyric acid receptor subunit alpha-4', 'gamma-aminobutyric acid (GABA) A receptor alpha 4', 'gamma-aminobutyric acid A receptor alpha 4', 'gamma-aminobutyric acid type A receptor alpha4 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha4', 'Gamma-aminobutyric acid receptor subunit alpha-6', 'GABRA6', 'GABA(A) receptor subunit alpha-6', 'GABA(A) receptor alpha 6', 'gamma-aminobutyric acid receptor subunit alpha-6', 'GABA subunit A receptor alpha 6', 'gamma-aminobutyric acid (GABA) A receptor alpha 6', 'gamma-aminobutyric acid type A receptor alpha6 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha6', 'Potassium channel subfamily K member 2', 'KCNK2', 'TREK', 'TREK1', 'K2p2.1', 'TREK-1', 'Outward rectifying potassium channel protein TREK-1', 'TREK-1 K(+) channel subunit', 'Two pore domain potassium channel TREK-1', 'Two pore potassium channel TPKC1', 'TPKC1', 'hTREK-1c', 'hTREK-1e', 'potassium channel subfamily K member 2', 'K2P2.1 potassium channel', 'TWIK-related potassium channel 1', 'outward rectifying potassium channel protein TREK-1', 'potassium channel two pore domain subfamily K member 2', 'potassium inwardly-rectifying channel subfamily K member 2', 'tandem-pore-domain potassium channel TREK-1', 'two pore domain potassium channel TREK-1', 'two pore potassium channel TPKC1', 'two-pore potassium channel 1', 'potassium two pore domain channel subfamily K member 2', 'Gamma-aminobutyric acid receptor subunit alpha-3', 'GABRA3', 'GABA(A) receptor subunit alpha-3', 'GABA(A) receptor alpha 3', 'EPILX2', 'gamma-aminobutyric acid receptor subunit alpha-3', 'gamma-aminobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor alpha3 subunit', 'gamma-animobutyric acid (GABA) A receptor alpha 3', 'gamma-aminobutyric acid type A receptor subunit alpha3', 'Gamma-aminobutyric acid receptor subunit delta', 'GABRD', 'GABAARdelta', 'GABA(A) receptor subunit delta', 'GABA(A) receptor delta', 'EIG10', 'EJM7', 'GEFSP5', 'gamma-aminobutyric acid receptor subunit delta', 'GABA-A receptor delta polypeptide', 'gamma-aminobutyric acid (GABA) A receptor delta', 'gamma-aminobutyric acid type A receptor delta subunit', 'gamma-aminobutyric acid type A receptor subunit delta', 'Gamma-aminobutyric acid receptor subunit alpha-2', 'GABRA2', 'GABA(A) receptor subunit alpha-2', 'GABA(A) receptor alpha 2', 'DEE78', 'EIEE78', 'gamma-aminobutyric acid receptor subunit alpha-2', 'gamma-aminobutyric acid type A receptor alpha2 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha2', 'Gamma-aminobutyric acid receptor subunit beta-2', 'GABRB2', 'GABA(A) receptor subunit beta-2', 'GABA(A) receptor beta 2', 'DEE92', 'ICEE2', 'gamma-aminobutyric acid receptor subunit beta-2', 'gamma-aminobutyric acid A receptor beta 2', 'gamma-aminobutyric acid type A receptor beta2 subunit', 'gamma-aminobutyric acid type A receptor subunit beta2', 'Gamma-aminobutyric acid receptor subunit beta-3', 'GABRB3', 'GABA(A) receptor subunit beta-3', 'GABA(A) receptor beta 3', 'DEE43', 'ECA5', 'EIEE43', 'gamma-aminobutyric acid receptor subunit beta-3', 'GABA-alpha receptor beta-2 subunit', 'GABAA receptor beta-3 subunit', 'gamma-aminobutyric acid (GABA) A receptor beta 3', 'gamma-aminobutyric acid A receptor beta 3', 'gamma-aminobutyric acid type A receptor beta3 subunit', 'gamma-aminobutyric acid type A receptor subunit beta3', 'Gamma-aminobutyric acid receptor subunit gamma-3', 'GABRG3', 'GABA(A) receptor subunit gamma-3', 'GABA(G) receptor gamma 3', 'gamma-aminobutyric acid receptor subunit gamma-3', 'gamma-aminobutyric acid (GABA) A receptor gamma 3', 'gamma-aminobutyric acid type A receptor gamma3 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma3', 'Gamma-aminobutyric acid receptor subunit epsilon', 'GABRE', 'GABA(A) receptor subunit epsilon', 'GABA(A) receptor epsilon', 'gamma-aminobutyric acid receptor subunit epsilon', 'gamma-aminobutyric acid (GABA) A receptor epsilon', 'gamma-aminobutyric acid type A receptor epsilon subunit', 'gamma-aminobutyric acid type A receptor subunit epsilon', 'Gamma-aminobutyric acid receptor subunit alpha-1', 'GABRA1', 'EJM5', 'GABA(A) receptor subunit alpha-1', 'GABA(A) receptor alpha 1', 'DEE19', 'ECA4', 'EIEE19', 'EJM', 'gamma-aminobutyric acid receptor subunit alpha-1', 'gamma-aminobutyric acid (GABA) A receptor alpha 1', 'gamma-aminobutyric acid type A receptor alpha1 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha1', 'Potassium channel subfamily K member 18', 'KCNK18', 'TRESK', 'TRIK', 'K2p18.1', 'TRESK-2', 'TRESK2', 'TWIK-related individual potassium channel', 'TWIK-related spinal cord potassium channel', 'TWIK related spinal cord K+ channel', 'MGR13', 'potassium channel subfamily K member 18', 'TWIK-related individual K+ channel', 'TWIK-related spinal cord K+ channel', 'potassium channel two pore domain subfamily K member 18', 'potassium two pore domain channel subfamily K member 18', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'Gamma-aminobutyric acid receptor subunit pi', 'GABRP', 'GABA(A) receptor subunit pi', 'GABA(A) receptor pi', 'gamma-aminobutyric acid receptor subunit pi', 'gamma-aminobutyric acid (GABA) A receptor pi', 'gamma-aminobutyric acid type A receptor pi subunit', 'gamma-aminobutyric acid type A receptor subunit pi', 'Potassium channel subfamily K member 10', 'KCNK10', 'TREK2', 'K2p10.1', 'TREK-2', 'PPP1R97', 'Outward rectifying potassium channel protein TREK-2', 'TREK-2 K(+) channel subunit', 'protein phosphatase 1 regulatory subunit 97', 'potassium channel subfamily K member 10', '2P domain potassium channel TREK2', 'TWIK-related K+ channel 2', 'outward rectifying potassium channel protein TREK-2', 'potassium channel TREK-2', 'potassium channel two pore domain subfamily K member 10', 'potassium two pore domain channel subfamily K member 10', 'Gamma-aminobutyric acid receptor subunit theta', 'GABRQ', 'GABA(A) receptor subunit theta', 'GABA(A) receptor theta', 'THETA', 'gamma-aminobutyric acid receptor subunit theta', 'gamma-aminobutyric acid (GABA) A receptor theta', 'gamma-aminobutyric acid type A receptor theta subunit', 'gamma-aminobutyric acid type A receptor subunit theta', 'Gamma-aminobutyric acid receptor subunit gamma-1', 'GABRG1', 'GABA(A) receptor subunit gamma-1', 'GABA(A) receptor gamma', 'gamma-aminobutyric acid receptor subunit gamma-1', 'gamma-1 polypeptide', 'gamma-aminobutyric acid (GABA) A receptor gamma 1', 'gamma-aminobutyric acid type A receptor gamma1 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma1', 'Gamma-aminobutyric acid receptor subunit gamma-2', 'GABRG2', 'GABA(A) receptor subunit gamma-2', 'GABA(A) receptor gamma 2', 'CAE2', 'DEE74', 'ECA2', 'EIEE74', 'FEB8', 'GEFSP3', 'gamma-aminobutyric acid receptor subunit gamma-2', 'gamma-aminobutyric acid (GABA) A receptor gamma 2', 'gamma-aminobutyric acid type A receptor gamma2 subunit', 'gamma-aminobutyric acid type A receptor subunit gamma2', 'Glycine receptor subunit alpha-1', 'GLRA1', 'Glycine receptor 48 kDa subunit', 'Glycine receptor strychnine-binding subunit', 'stiff person syndrome', 'HKPX1', 'STHE', 'glycine receptor subunit alpha-1', 'glycine receptor 48 kDa subunit', 'glycine receptor strychnine-binding subunit', 'glycine receptor alpha 1', 'Gamma-aminobutyric acid receptor subunit alpha-5', 'GABRA5', 'GABA(A) receptor subunit alpha-5', 'GABA(A) receptor alpha 5', 'DEE79', 'EIEE79', 'gamma-aminobutyric acid receptor subunit alpha-5', 'gamma-aminobutyric acid (GABA) A receptor alpha 5', 'gamma-aminobutyric acid type A receptor alpha5 subunit', 'gamma-aminobutyric acid type A receptor subunit alpha5', 'Gamma-aminobutyric acid receptor subunit beta-1', 'GABRB1', 'GABA(A) receptor subunit beta-1', 'GABA(A) receptor beta 1', 'DEE45', 'EIEE45', 'gamma-aminobutyric acid receptor subunit beta-1', 'gamma-aminobutyric acid (GABA) A receptor beta 1', 'gamma-aminobutyric acid type A receptor beta1 subunit', 'gamma-aminobutyric acid type A receptor subunit beta1', 'phenotype', 'injury poisoning or other complication', 'cardiovascular disease', 'integumentary system disease', 'cancer or benign tumor', 'reproductive system or breast disease', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease', 'urinary system disease', 'infectious disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1979 and has 6 investigational indications.,[],pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192124,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192168,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922832,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922807,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918592,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922816,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs144336148,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs1801086,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922802,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192161,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922818,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192176,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192122,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192163,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918594,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192172,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs112563513,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192170,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922770,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192177,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918593,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192163,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922747,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192172,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922832,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs112563513,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192175,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933396,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922753,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs63749869,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922809,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922770,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922772,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922809,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192124,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922764,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,develop malignant hyperthermia,,rs193922878,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1801086,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192168,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192124,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922772,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922768,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,risk for Malignant Hyperthermia,,rs1800559,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922843,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922764,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922803,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs28933397,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918593,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922753,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922807,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918596,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,increased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922768,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922748,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs118192167,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918594,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192122,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922816,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192175,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192116,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922747,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192162,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922802,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192177,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922818,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918595,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918595,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922762,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922878,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922876,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs111888148,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192161,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922878,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs111888148,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192162,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192176,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918592,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922843,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192178,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192167,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918596,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922803,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922876,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,malignant hyperthermia,,rs28933396,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922748,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922762,FALSE
CHEMBL1257,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",ENFLURANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1972.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933397,FALSE
CHEMBL1754,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DOXAPRAM,Yes,BLOCKER,Potassium channel subfamily K member 3 blocker,"['premature birth', 'Births Premature', 'Birth Preterm', 'Births Preterm', 'Premature Births', 'Preterm Birth', 'Preterm Births', 'Birth Premature', 'hypoxia', 'lung disease', 'LUNG DIS', 'PULM DIS', 'disease or disorder of lung', 'Disease Pulmonary', 'pulmonary disorders', 'lung disorder', 'pulmonary disorder', 'Pulmonary Diseases', 'pulmonary disease', 'disease of lung', 'lung disease or disorder', 'Diseases Lung', 'Pulmonary Disease', 'disorder of lung', 'DIS PULM', 'Diseases Pulmonary', 'pulmonary diseases', 'Lung Diseases', 'Disease Lung', 'lung disorders', 'Apnea', 'Apneic episodes', 'Apnoea', 'Absence of spontaneous respiration', 'respiratory system disease', 'Other diseases of respiratory system NOS (disorder)', 'Disease of respiratory system', 'Unspecified disease of respiratory system', 'Other respiratory system diseases NOS', '[X]Respiratory conditions due to other specified external agents', 'Other respiratory system diseases NOS (disorder)', 'Other diseases of trachea and bronchus not elsewhere classified', '[X]Chronic and other pulmonary manifestations due to radiation (disorder)', 'ALVEOL PNEUMONOPATHY NOS', 'Respiratory conditions due to other specified external agents', 'CHR PUL MANIF D/T RADIAT', 'Lung involvement in other diseases classified elsewhere', 'Other respiratory system diseases', 'INORG DUST PNEUMOCON NEC', 'respiratory system disorder', 'Respiratory disorder NOS', '[X]Respiratory conditions due to unspecified external agent (disorder)', 'Other diseases of respiratory system', 'PNEUMOCONIOSES AND OTHER LUNG DISEASES DUE TO EXTERNAL AGENTS', 'Respiratory disorder', 'Respiratory System Disorder', 'disease of respiratory system', 'Respiratory conditions due to unspecified external agent', 'DISEASES OF THE RESPIRATORY SYSTEM', 'Other specified alveolar and parietoalveolar pneumonopathies', 'disorder of respiratory system', 'Other diseases of respiratory system NOS', 'Respiratory conditions due to other and unspecified external agents', 'Disorder of respiratory system', 'RESP SYSTEM DISEASE NOS', '[X]Chronic and other pulmonary manifestations due to radiation', 'Unspecified alveolar and parietoalveolar pneumonopathy', 'MEDIASTINUM DISEASE NEC', 'Disease of respiratory system NOS', 'Respiratory system diseases NOS', '[X]Respiratory conditions due to unspecified external agent', '[X]Respiratory conditions due to other specified external agents (disorder)', '[X]Other diseases of the respiratory system (disorder)', 'Respiratory system diseases NOS (disorder)', 'RESP COND: EXT AGENT NEC', 'LUNG INVOLV IN OTH DIS', 'RESP COND: EXT AGENT NOS', 'Pneumoconiosis due to other inorganic dust', 'Disorder of respiratory system (disorder)', 'Other diseases of respiratory system not elsewhere classified', 'Other alveolar and parietoalveolar pneumonopathy', 'Other respiratory system diseases (disorder)', 'Other diseases of mediastinum not elsewhere classified', 'ALVEOL PNEUMONOPATHY NEC', 'RESP SYSTEM DISEASE NEC', 'Lung involvement in conditions classified elsewhere', 'Disease of respiratory system (disorder)', 'disease or disorder of respiratory system', 'respiratory system disease or disorder', 'respiratory disorder', '[X]Other diseases of the respiratory system', 'respiratory disease', 'Respiratory disease', 'Chronic and other pulmonary manifestations due to radiation', 'panic disorder', 'panic anxiety syndrome', 'panic disorder syndrome', 'panic syndrome', 'panic attack', 'panic attacks', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'phenotype', 'respiratory or thoracic disease', 'psychiatric disorder', 'nervous system disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1965 and is indicated for respiratory system disease and lung disease and has 1 investigational indication.,"['EFO_0000684', 'EFO_0003818']","","","",,"",
CHEMBL3989519,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",DOXAPRAM HYDROCHLORIDE,Yes,BLOCKER,Potassium channel subfamily K member 3 blocker,"['hypoxia', 'premature birth', 'Births Premature', 'Birth Preterm', 'Births Preterm', 'Premature Births', 'Preterm Birth', 'Preterm Births', 'Birth Premature', 'Apnea', 'Apneic episodes', 'Apnoea', 'Absence of spontaneous respiration', 'panic disorder', 'panic anxiety syndrome', 'panic disorder syndrome', 'panic syndrome', 'panic attack', 'panic attacks', 'lung disease', 'LUNG DIS', 'PULM DIS', 'disease or disorder of lung', 'Disease Pulmonary', 'pulmonary disorders', 'lung disorder', 'pulmonary disorder', 'Pulmonary Diseases', 'pulmonary disease', 'disease of lung', 'lung disease or disorder', 'Diseases Lung', 'Pulmonary Disease', 'disorder of lung', 'DIS PULM', 'Diseases Pulmonary', 'pulmonary diseases', 'Lung Diseases', 'Disease Lung', 'lung disorders', 'Potassium channel subfamily K member 9', 'KCNK9', 'TASK3', 'Two pore K(+) channel KT3.2', 'K2p9.1', 'TASK-3', 'Acid-sensitive potassium channel protein TASK-3', 'TWIK-related acid-sensitive K(+) channel 3', 'Two pore potassium channel KT3.2', 'TWIK-related acid-sensitive K+ 3', 'BIBARS', 'KT3.2', 'TASK32', 'potassium channel subfamily K member 9', 'acid-sensitive potassium channel protein TASK-3', 'potassium 2-pore domain leak channel TASK3', 'potassium channel two pore domain subfamily K member 9', 'two pore K(+) channel KT3.2', 'two pore potassium channel KT3.2', 'potassium two pore domain channel subfamily K member 9', 'Potassium channel subfamily K member 3', 'KCNK3', 'TASK', 'TASK1', 'Two pore K(+) channel KT3.1', 'K2p3.1', 'TASK-1', 'Acid-sensitive potassium channel protein TASK-1', 'TWIK-related acid-sensitive K(+) channel 1', 'Two pore potassium channel KT3.1', 'TWIK-related acid-sensitive K+ 1', 'OAT1', 'PPH4', 'TBAK1', 'potassium channel subfamily K member 3', 'TWIK-related acid-sensitive K+ channel', 'acid-sensitive potassium channel protein TASK', 'acid-sensitive potassium channel protein TASK-1', 'cardiac potassium channel', 'potassium channel two pore domain subfamily K member 3', 'potassium inwardly-rectifying channel subfamily K member 3', 'two P domain potassium channel', 'two pore K(+) channel KT3.1', 'two pore potassium channel KT3.1', 'potassium two pore domain channel subfamily K member 3', 'phenotype', 'psychiatric disorder', 'nervous system disease', 'respiratory or thoracic disease']",single protein,Small molecule drug with a maximum clinical trial phase of IV (across all indications) that was first approved in 1965 and is indicated for lung disease and has 1 investigational indication.,['EFO_0003818'],"","","",,"",
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922747,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs112563513,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922768,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922753,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,develop malignant hyperthermia,,rs193922878,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs28933397,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192170,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192162,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs111888148,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192168,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192177,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922770,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,increased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918594,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922809,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs63749869,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs144336148,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192116,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922762,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922747,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922770,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192176,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs1801086,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922764,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922807,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922816,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192163,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922876,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922878,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192175,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs28933396,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192122,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918596,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918595,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922753,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922876,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192172,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918592,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922816,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192161,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918593,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922772,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922878,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192168,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918595,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs121918594,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918593,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922818,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922748,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1801086,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933397,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,risk for malignant hyperthermia,,rs118192167,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192178,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs112563513,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918592,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922843,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192124,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922772,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922843,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192161,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192172,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922803,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922748,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192175,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia susceptibility,,rs118192167,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922803,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs1800559,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922809,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs121918596,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922802,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192122,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922818,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192177,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922802,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922762,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922832,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs193922832,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs28933396,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,malignant hyperthermia,,rs118192162,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs111888148,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192124,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192178,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192176,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922768,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922764,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,increased risk for malignant hyperthermia,,rs772226819,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs193922807,FALSE
CHEMBL931,KCNK3,KCNK3,"LVM, LVM_BSA, RVEDV, RVEDV_BSA, RVESV_BSA, RVESV, RVESV_BSA, RVEDV, RVEDV_BSA, RVESV","","",HALOTHANE,No,OPENER,Potassium channel subfamily K member 3 opener,[],single protein,Small molecule drug with a maximum clinical trial phase of IV that was first approved in 1958.,"",pharmgkb,toxicity,decreased risk for malignant hyperthermia,,rs118192163,FALSE