How to determine the number of the genes in the final result of perturbation?
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jialei233
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Thank you for your interest in Geneformer! Our methodology, and what we would recommend, is filtering genes by statistical significance with multiple hypothesis correction (Goal_end_FDR). You can also subset to genes that move towards or away from an alternate state that you are interested in. Please see the supplementary tables in the manuscript for the output of our in silico perturbation to determine the number of statistically significant genes. Please also see the documentation about the output of the in silico perturber stats module for more information about each column.
ctheodoris
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