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CC#N.CCCCc1nc(N)c2c(n1)c(CCCCO)cn2COCc1ccccc1.CCC[N+](CCC)(CCC)CCC~O=[Ru](=O)(=O)[O-].C[N+]1([O-])CCOCC1.ClCCl>>CCCCc1nc(N)c2c(n1)c(CCCC=O)cn2COCc1ccccc1 | 142 |
CC(C)(C)CCCN1C(c2ccc(C(F)(F)F)cc2)CC(F)(F)C(CC(=O)OC(C)(C)C)C1c1ccc(C(F)(F)F)cc1.ClCCl.O=C(O)C(F)(F)F>>CC(C)(C)CCCN1C(c2ccc(C(F)(F)F)cc2)CC(F)(F)C(CC(=O)O)C1c1ccc(C(F)(F)F)cc1 | 278 |
CC(=O)[O-].CC(=O)[O-].COCCOC.Clc1cc(Cl)nc(Cl)n1.O=C([O-])[O-].OB(O)c1ccc(F)c(Cl)c1.[Na+].[Na+].[Pd+2].c1ccc(P(c2ccccc2)c2ccccc2)cc1>>Fc1ccc(-c2cc(Cl)nc(Cl)n2)cc1Cl | 884 |
C1COCCO1.CC(=O)[O-].CC(=O)[O-].CC(C)(C)OC(=O)N1CCN(c2cc(C#N)cc(N)c2Cl)C(=O)C1.CC1(C)c2cccc(P(c3ccccc3)c3ccccc3)c2Oc2c(P(c3ccccc3)c3ccccc3)cccc21.COc1ccc(CN(c2nc(Cl)nn3c(C#N)cnc23)C2CC2)cc1.O=C([O-])[O-].[Cs+].[Cs+].[Fe+2].[Pd+2].c1ccc(P(c2ccccc2)[c-]2cccc2)cc1.c1ccc(P(c2ccccc2)[c-]2cccc2)cc1>>COc1ccc(CN(c2nc(Nc3cc(C#N)cc(N4CCN(C(=O)OC(C)(C)C)CC4=O)c3Cl)nn3c(C#N)cnc23)C2CC2)cc1 | 990 |
BrB(Br)Br.CC#N.CC(C)=O~O=C=O.CCc1cc(-c2ccc(-c3cc[nH]n3)cc2)ccc1OC.ClCCl.O>>CCc1cc(-c2ccc(-c3cc[nH]n3)cc2)ccc1O | 48 |
CC(=O)[O-].CC(=O)[O-].CCN(CC)CC.CCOC(C)=O.Cc1ccc(Br)cc1O.ClCCl.OB(O)c1ccccc1.[Cu+2]>>Cc1ccc(Br)cc1Oc1ccccc1 | 920 |
C1CCOC1.CN(C)C=O.Cc1ccc(S(=O)(=O)OCC2CC(c3ccc(CN4CCCC4)cc3)C2)cc1.O=C([O-])[O-]~[K+]~[K+].c1cnc(N2CCNCC2)nc1>>c1cnc(N2CCN(CC3CC(c4ccc(CN5CCCC5)cc4)C3)CC2)nc1 | 429 |
C1CCOC1~CO.CC1Oc2ccc(CCN)cc2NC1=O.O.O=Cc1cccc(Cl)c1.[BH4-]~[Na+]>>CC1Oc2ccc(CCNCc3cccc(Cl)c3)cc2NC1=O | 468 |
C1CCOC1.CC(C)OC(=O)N=NC(=O)OC(C)C.CCCCC(O)CCCC.Cc1cc([N+](=O)[O-])c(C)cc1O.c1ccc(P(c2ccccc2)c2ccccc2)cc1>>CCCCC(CCCC)Oc1cc(C)c([N+](=O)[O-])cc1C | 846 |
COc1cc(C#N)c([N+](=O)[O-])c(F)c1OC.O.O=S([O-])S(=O)[O-].[Na+].[Na+]>>COc1cc(C#N)c(N)c(F)c1OC | 202 |
COc1ccc(Cn2cc(-c3nc(Nc4ccccn4)cs3)c(C(F)(F)F)n2)cc1.O=C(O)C(F)(F)F.O=C([O-])[O-]~[Na+]~[Na+]>>FC(F)(F)c1n[nH]cc1-c1nc(Nc2ccccn2)cs1 | 940 |
C1CCOC1.CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)OC)CCN3C(C)C)cc1.CO.[Na+]~[OH-]>>CCCCOCCOc1ccc(-c2ccc3c(c2)C=C(C(=O)O)CCN3C(C)C)cc1 | 58 |
CC[C@@H]1C(=O)N(C)c2cnc(Cl)nc2N1C1CCCC1.CN1CCNCC1.CS(C)=O.O>>CC[C@@H]1C(=O)N(C)c2cnc(N3CCN(C)CC3)nc2N1C1CCCC1 | 36 |
CCOC(=O)C1(O)CCCc2ccc(Cl)cc21.CS(C)=O.O~[Cl-]~[Na+].[Na+]~[OH-]>>O=C(O)C1(O)CCCc2ccc(Cl)cc21 | 7 |
CNC(=O)c1ccc(Nc2c(C(=O)O)ccc(F)c2F)c(F)c1.COc1nc(OC)nc([N+]2(C)CCOCC2)n1.NOCCO.[Cl-]>>CNC(=O)c1ccc(Nc2c(C(=O)NOCCO)ccc(F)c2F)c(F)c1 | 741 |
CC(C)=O.CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc([C@H](N)C(=O)OC)cc2)c(C)c1.Cl>>CCC(CC)(c1ccc(CCC(O)C(C)(C)C)c(C)c1)c1ccc(-c2ccc([C@H](N)C(=O)O)cc2)c(C)c1 | 88 |
CC(=O)Cc1ccc(O)cc1.NCC(O)c1csc(C(F)(F)F)n1>>CC(Cc1ccc(O)cc1)NCC(O)c1csc(C(F)(F)F)n1 | 236 |
CC(C)O.CCOC(=O)C(=C(C)C)c1cnc(C(C)(C)C)nc1.O.[Na+]~[OH-]>>CC(C)=C(C(=O)O)c1cnc(C(C)(C)C)nc1 | 122 |
COc1ccccc1N.O=C(O)c1ccncc1>>COc1ccccc1NC(=O)c1ccncc1 | 50 |
COC(=O)[C@H](Cc1ccc(OC)cc1)NC(=O)[C@H](C)NC(=O)c1cn2ccccc2n1.C[Sn+](C)C~[OH-].ClCCCl>>COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)c2cn3ccccc3n2)C(=O)O)cc1 | 88 |
CCCN1CCCNCC1.O=[N+]([O-])c1ccc(F)cc1>>CCCN1CCCN(c2ccc([N+](=O)[O-])cc2)CC1 | 26 |
CCOC(=O)c1coc2c1C(=O)C(C)(C)CC2.CCOC(=O)c1coc2c1C(=O)C(C)(C)OC2>>CC1(C)OCc2occ(C(=O)O)c2C1=O | 171 |
CC(=O)OC(C)=O.NC1CCC(N2CCCC(N3CCc4cncc5cccc3c45)C2)CC1>>CC(=O)NC1CCC(N2CCCC(N3CCc4cncc5cccc3c45)C2)CC1 | 339 |
O=c1cc(CBr)c2ccc(F)c(F)c2[nH]1.c1ccc2[nH]c(-n3ccnc3)nc2c1>>O=c1cc(Cn2c(-n3ccnc3)nc3ccccc32)c2ccc(F)c(F)c2[nH]1 | 593 |
CC(C)(C)OC(=O)Nc1cc(Cl)c(C(F)(F)F)cc1NC(=O)CC(=O)c1cccc(-c2cncnc2)c1.ClCCl.O=C(O)C(F)(F)F>>O=C1CC(c2cccc(-c3cncnc3)c2)=Nc2cc(Cl)c(C(F)(F)F)cc2N1 | 930 |
CC(=O)O.CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1N.CO.O=C([O-])O~[Na+].O=C1CCCC1.[BH3-]C#N~[Na+]>>CCOC(=O)[C@@H]1[C@H]2CC[C@H](C2)[C@@H]1NC1CCCC1 | 236 |
CC(=O)O.O=[N+]([O-])c1ccccc1C=C1CCCCC1.[Fe]>>Nc1ccccc1C=C1CCCCC1 | 1 |
ClCCl.O=C(O)CCSCCC(F)(F)F.O=S(Cl)Cl>>O=C(Cl)CCSCCC(F)(F)F | 53 |
CCN=C=NCCCN(C)C.CN(C)C=O.CN(C)c1ccncc1.Cl.Nc1cccc2[nH]ccc12.O=C(O)CC1C2CC3CC(C2)CC1C3>>O=C(CC1C2CC3CC(C2)CC1C3)Nc1cccc2[nH]ccc12 | 365 |
CC(=O)Cl.CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](c3cccc(F)c3)CC2)CC1.Cc1ccccc1.Cl.O=[N+]([O-])c1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-]>>CCC[C@@H]1CC[C@@H]([C@@H]2CC[C@@H](c3ccc(C(C)=O)c(F)c3)CC2)CC1 | 31 |
COCC(=O)Cl.Cl~O=C(NC1CCNCC1)c1c[nH]c2c(-c3c(OCC4CC4)ccc4c3OCO4)ncnc12>>COCC(=O)N1CCC(NC(=O)c2c[nH]c3c(-c4c(OCC5CC5)ccc5c4OCO5)ncnc23)CC1 | 125 |
BrCc1ccccc1.C1CCOC1.Oc1ccc(F)cc1Cl.[H-]~[Na+]>>Fc1ccc(OCc2ccccc2)c(Cl)c1 | 127 |
C1CCOC1.CCCCC1CCC(c2ccc(Cc3ccc([N+](=O)[O-])cc3)cc2)(c2ccc(Cc3ccc([N+](=O)[O-])cc3)cc2)CC1.O.[H][H]>>CCCCC1CCC(c2ccc(Cc3ccc(N)cc3)cc2)(c2ccc(Cc3ccc(N)cc3)cc2)CC1 | 204 |
CC(=O)[O-].CCO.COc1ccc(C#Cc2cnccc2C=O)cc1.Cl.NO.O.[Na+]>>COc1ccc(C#Cc2cnccc2C=NO)cc1 | 30 |
C1CCOC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Cc1ccccc1.ClCCl.Nc1cc(F)c(C(F)(F)F)cc1[N+](=O)[O-].Nc1ccc(C(F)(F)F)c(F)c1.O=C(O)C(F)(F)F.O=[N+]([O-])O.[Na+].[OH-]>>CC(C)(C)OC(=O)Nc1cc(F)c(C(F)(F)F)cc1[N+](=O)[O-] | 735 |
CCO.COc1ccc([N+](=O)[O-])c(NCCN2CCC(NC(=O)OC(C)(C)C)CC2)n1.[Pd]>>COc1ccc(N)c(NCCN2CCC(NC(=O)OC(C)(C)C)CC2)n1 | 269 |
CCN(CC)CC.CCN=C=NCCCN(C)C.Cl.Cl.ClCCl.N#Cc1c[nH]c(-c2nc([C@H]3CCCNC3)no2)c1.O=C(O)c1ccc(F)nc1.On1nnc2cccnc21>>N#Cc1c[nH]c(-c2nc([C@H]3CCCN(C(=O)c4ccc(F)nc4)C3)no2)c1 | 256 |
C=CC[C@H](NC(=O)OC(C)(C)C)c1cncc(-c2c([N+](=O)[O-])cnn2C(F)F)c1.CC(C)=O.O.[Cl-].[NH4+].[Zn]>>C=CC[C@H](NC(=O)OC(C)(C)C)c1cncc(-c2c(N)cnn2C(F)F)c1 | 628 |
C1CCOC1.CCOC(=O)Cc1nc(-c2ccc(C(F)(F)F)cc2)oc1CC.[Al+3]~[H-]~[H-]~[H-]~[H-]~[Li+]>>CCc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCO | 225 |
CC(=O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C.CCO.[BH4-].[Na+]>>CC(O)CCCCn1cnc2c1c(=O)n(C)c(=O)n2C | 91 |
CC(=O)OI1(OC(C)=O)(OC(C)=O)OC(=O)c2ccccc21.CC(C)(C)OC(=O)N1CCC(O)C(Sc2ccc(Br)cc2)C1>>CC(C)(C)OC(=O)N1CCC(=O)C(Sc2ccc(Br)cc2)C1 | 87 |
CC(=O)N(C)C.CCOC(C)=O.CN(C)c1ccccc1-c1ccccc1P(C1CCCCC1)C1CCCCC1.COc1c([N+](=O)[O-])ccc(Br)c1F.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1~O=C(/C=C/c1ccccc1)/C=C/c1ccccc1~O=C(/C=C/c1ccccc1)/C=C/c1ccccc1~[Pd]~[Pd].[C-]#N~[C-]#N~[Zn+2].[Pd]>>COc1c([N+](=O)[O-])ccc(C#N)c1F | 65 |
CCN(CC)CC.CCOC(=O)NCC(C)O.CS(=O)(=O)Cl.Cl>>CCOC(=O)NCC(C)OS(C)(=O)=O | 0 |
CC1(C)CCC(=O)CC1.CCO.Cl~NO.O.O=C([O-])[O-]~[Na+]~[Na+]>>CC1(C)CCC(=NO)CC1 | 86 |
CC(C)CC(=O)Cl.COc1cccc(Cl)c1Cl.Cl.ClCCl.[Al+3].[Cl-].[Cl-].[Cl-]>>COc1ccc(C(=O)CC(C)C)c(Cl)c1Cl | 31 |
CC(C)(Cc1cccc(C(=O)O)c1)NC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c(CO)c1.CCN(CC)CC.CCN=C=NCCCN(C)C.Cl.ClCCl.NCCc1ccc(Cl)cc1.O.On1nnc2ccccc21>>CC(C)(Cc1cccc(C(=O)NCCc2ccc(Cl)cc2)c1)NC[C@H](O[Si](C)(C)C(C)(C)C)c1ccc(O)c(CO)c1 | 334 |
CCCCCCc1ccc(-c2ccc(-c3ncc(C(=O)OCC)cn3)cc2)cc1.CCO.[Na+].[OH-]>>CCCCCCc1ccc(-c2ccc(-c3ncc(C(=O)O)cn3)cc2)cc1 | 171 |
CC(C)(C)O.CCCCCCCCc1ccc(OCC(O)Cn2ccc3cc(C#N)ccc32)cc1.Cl.O.[K+].[OH-]>>CCCCCCCCc1ccc(OCC(O)Cn2ccc3cc(C(N)=O)ccc32)cc1 | 419 |
CCCCCCCOc1ccc(COc2ccc(C(=O)OCC)cc2)cc1.CCO.[K+].[OH-]>>CCCCCCCOc1ccc(COc2ccc(C(=O)O)cc2)cc1 | 386 |
CCN(CC)CC.CNC.COc1cc(CO)ccc1[N+](=O)[O-].CS(=O)(=O)Cl.Cl.ClCCl>>COc1cc(CN(C)C)ccc1[N+](=O)[O-] | 765 |
CCN(CC)CC.CS(C)=O.ClCCl.O=C(Cl)C(=O)Cl.O=C(NCCCCO)OCc1ccccc1>>O=CCCCNC(=O)OCc1ccccc1 | 142 |
C1CCOC1.CCN(CC)CC.Cc1noc(C)c1COc1ccc(CC(=O)O)nc1.Cl.ClCCCl.NC(c1ccccc1)c1ccc(Cl)cc1.O.On1nnc2ccccc21>>Cc1noc(C)c1COc1ccc(CC(=O)NC(c2ccccc2)c2ccc(Cl)cc2)nc1 | 769 |
C1CCOC1.Cl.NC(=O)C1CNc2cccc(F)c2O1.[Al+3].[H-].[H-].[H-].[H-].[Li+]>>NCC1CNc2cccc(F)c2O1 | 363 |
CC(=O)O.O=C1CCC(=O)N1I.O=C1Cc2ccccc2N1>>O=C1Cc2cc(I)ccc2N1 | 834 |
CC(=O)c1cccc(Cc2cc3cccc(-c4cccc(C(=O)O)c4)c3s2)c1.COCCN>>COCCNC(=O)c1cccc(-c2cccc3cc(Cc4cccc(C(C)=O)c4)sc23)c1 | 334 |
N#CCC(=O)O.NC(N)=O.NCc1ccccc1.Nc1c(N)n(-c2ccccc2)c(=O)n(Cc2ccccc2)c1=O.Nc1cc(=O)n(Cc2ccccc2)c(=O)n1-c1ccccc1.O=C=Nc1ccccc1.O=N[O-]~[Na+].[H][H]>>O=C(NCc1ccccc1)Nc1ccccc1 | 814 |
Brc1ccc(Br)nc1.CC(=O)N1CCNCC1>>CC(=O)N1CCN(c2ccc(Br)cn2)CC1 | 647 |
CCN1C[C@H](N)[C@@H](OC)C1.O=C(O)c1cc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1>>CCN1C[C@H](NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)[C@@H](OC)C1 | 736 |
CCN(CC)CC.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CNC1CCN(C(=O)OC(C)(C)C)CC1.ClCCl.F[P-](F)(F)(F)(F)F.O=C(O)c1ccccc1>>CN(C(=O)c1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1 | 44 |
C#Cc1cc(NC(=O)Nc2ccc(C(=O)OCC)c(F)c2)cc2c1OC(C)(C)CC2(C)C.C1CCOC1.CO.O.[Li+]~[OH-]>>C#Cc1cc(NC(=O)Nc2ccc(C(=O)O)c(F)c2)cc2c1OC(C)(C)CC2(C)C | 5 |
C1CCOC1.CC(O)c1cnc(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)s1.CI.C[Si](C)(C)[N-][Si](C)(C)C.[Na+]>>COC(C)c1cnc(-c2ccc(C(F)(F)F)cc2CN2C(=O)O[C@H](c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[C@@H]2C)s1 | 140 |
CC#N.CCOC(=O)CCc1ccc(O)c2c1CCCC2.Cc1nc(-c2ccc(C(F)(F)F)cc2)ccc1CCl.O=C([O-])[O-].[Cs+].[Cs+]>>CCOC(=O)CCc1ccc(OCc2ccc(-c3ccc(C(F)(F)F)cc3)nc2C)c2c1CCCC2 | 678 |
CC(C(=O)O)c1ccc2c(c1)CCc1ccccc1C2=O.O=S(Cl)Cl>>CC(C(=O)Cl)c1ccc2c(c1)CCc1ccccc1C2=O | 53 |
CC(=O)Cl.COc1ccc2c3c4c(ccc3n(CCCN(C)C)c2c1)C(=O)CC4.O.O=C([O-])[O-].O=[N+]([O-])c1ccccc1.[Al+3].[Cl-].[Cl-].[Cl-].[Na+].[Na+]>>COc1cc2c(cc1C(C)=O)c1c3c(ccc1n2CCCN(C)C)C(=O)CC3 | 31 |
BrBr.CC(=O)O.CCCCc1ccc(NC(C)=O)cc1>>CCCCc1ccc(NC(C)=O)c(Br)c1 | 98 |
C1CCOC1.CN(C)C=O.COc1ccc(C2CCc3cc(OC(=O)C(C)(C)C)ccc3C2)c(NCCCc2ccc(CC(=O)O)cc2)c1.O=C(Cl)C(=O)Cl>>COc1ccc(C2CCc3cc(OC(=O)C(C)(C)C)ccc3C2)c(NCCCc2ccc(CC(=O)Cl)cc2)c1 | 56 |
CCOC(C)=O.CO.C[O-]~[Na+].Cc1ccc(S(=O)(=O)n2cc(C)c3c(-c4nc(Cl)c5c(n4)CCN(c4cc(C(C)C)ccc4C)C5)cccc32)cc1.ClCCl.O.O~[Cl-]~[Na+].[K+]~[OH-].[NH4+]~[OH-]>>COc1nc(-c2cccc3c2c(C)cn3S(=O)(=O)c2ccc(C)cc2)nc2c1CN(c1cc(C(C)C)ccc1C)CC2 | 461 |
CC(=O)O.CC(=O)[O-].CO.Cn1cnc(S(=O)(=O)N2C[C@@H](N)[C@H](c3ccc(F)cc3)C2)c1.O=Cc1ccccc1.O=S(=O)([O-])[O-].[Mg+2].[Na+]>>Cn1cnc(S(=O)(=O)N2C[C@@H](NCc3ccccc3)[C@H](c3ccc(F)cc3)C2)c1 | 468 |
CC(=O)[O-].CC(=O)[O-].CC(C)(C)[O-].CC(C)c1cc(C(C)C)c(-c2ccccc2P(C2CCCCC2)C2CCCCC2)c(C(C)C)c1.C[C@@H]1CN(C(=O)OC(C)(C)C)CCN1.Cc1ccc(Br)c(C)c1.Cc1ccccc1.[Na+].[Pd+2]>>Cc1ccc(N2CCN(C(=O)OC(C)(C)C)C[C@H]2C)c(C)c1 | 294 |
CCN(CC)CC.COc1cccc([C@H]2O[C@H](CCO)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC.CS(=O)(=O)Cl.ClCCl.O=C([O-])O~[Na+]>>COc1cccc([C@H]2O[C@H](CCOS(C)(=O)=O)c3nnc(C(C)C)n3-c3ccc(Cl)cc32)c1OC | 0 |
CCC(C)=O.CCCOc1nc2c(Cl)cc(F)c(-n3c(=O)cc(C(F)(F)F)[nH]c3=O)c2s1.CI.O=C([O-])[O-]~[K+]~[K+]>>CCCOc1nc2c(Cl)cc(F)c(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)c2s1 | 570 |
CCN(C(C)C)C(C)C.CN(C)C(On1nnc2cccnc21)=[N+](C)C~F[P-](F)(F)(F)(F)F.CN(C)C=O.Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(C(=O)O)c2c1.N[C@@H]1CCNC1>>Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)n(CC3CC3)cc(C(=O)N3CC[C@@H](N)C3)c2c1 | 256 |
CC(=O)c1ccc(N)cc1.Nc1nc(Cl)cc(-c2cccc(Cl)c2)n1>>CC(=O)c1ccc(Nc2cc(-c3cccc(Cl)c3)nc(N)n2)cc1 | 161 |
C1COCCO1.C1COCCO1.CC(=O)N(Cc1ccccc1)C1CCN(C(=O)OC(C)(C)C)CC1.Cl>>CC(=O)N(Cc1ccccc1)C1CCNCC1 | 575 |
CI.CN(C)C=O.CSc1cc(C(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c[nH]1.[H-]~[Na+]>>CSc1cc(C(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cn1C | 191 |
C1CCOC1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.CCN(CC)CC.CCOC(C)=O.CN(C)c1ccncc1.Nc1n[nH]c2ccc(-c3ncccc3Cl)cc12>>CC(C)(C)OC(=O)n1nc(N)c2cc(-c3ncccc3Cl)ccc21 | 841 |
C1CCOC1.COCOc1cc(CCc2ccc(OCC3CC3)cc2)ccc1C(=O)OC.O.[Al+3]~[H-]~[H-]~[H-]~[H-]~[Li+].[Na+]~[OH-]>>COCOc1cc(CCc2ccc(OCC3CC3)cc2)ccc1CO | 444 |
ClCCl.N#Cc1cccc(-c2ccccc2C(=O)O)c1.O=S(Cl)Cl>>N#Cc1cccc(-c2ccccc2CO)c1 | 72 |
C1CCOC1.CC(C)C[Al+]CC(C)C~[H-].CCOC(C)=O.CCc1nn(C2CC2)c2cc(-c3ccnn3-c3ccc(C(=O)OC)cc3)ccc12.CO.Cc1ccccc1.O>>CCc1nn(C2CC2)c2cc(-c3ccnn3-c3ccc(CO)cc3)ccc12 | 444 |
CC(=O)O.CC(=O)O[BH-](OC(C)=O)OC(C)=O~[Na+].CC=O.ClCCCl.Fc1ccc(-c2[nH]c(C3CCNCC3)cc2-c2ccncc2)cc1>>CCN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 | 484 |
C1CCOC1.CCOC(C)=O.COC(=O)c1nc2c(C(F)(F)F)cc(OC(F)F)cn2c1Cl.Cl.O.[Na+].[OH-]>>O=C(O)c1nc2c(C(F)(F)F)cc(OC(F)F)cn2c1Cl | 152 |
CCOC(C)=O.O=[N+]([O-])c1ccc(OC(F)(F)F)c(CO)c1>>Nc1ccc(OC(F)(F)F)c(CO)c1 | 202 |
C1CCOC1.CCO.CCOC(=O)c1cn2c(cc1=O)-c1cc(OC)c(OCc3ccccc3)cc1CC2C(C)(C)COC.Cl.[Li+].[OH-]>>COCC(C)(C)C1Cc2cc(OCc3ccccc3)c(OC)cc2-c2cc(=O)c(C(=O)O)cn21 | 171 |
CCOC(C)=O.Cc1ccc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c([N+](=O)[O-])c1.[Pd]>>Cc1ccc(C(C(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c(N)c1 | 1 |
CCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)C#N.CCO.O.OO.[NH4+]~[OH-]>>CCCn1nc2c(N)nc3ccccc3c2c1CC(C)(C)C(N)=O | 632 |
CCN(CCc1noc(-c2ccc(F)c(F)c2)n1)C(=O)OC(C)(C)C.ClC(Cl)Cl.O=C(O)C(F)(F)F.O=C([O-])O.[Na+]>>CCNCCc1noc(-c2ccc(F)c(F)c2)n1 | 575 |
C1CCNC1.CCO.O=C([O-])[O-]~[K+]~[K+].O=Cc1cccc(CBr)c1>>O=Cc1cccc(CN2CCCC2)c1 | 248 |
BrB(Br)Br~ClCCl.CCOC(C)=O.COc1ccc2c(C(C)NC(C)=O)noc2c1.Cc1ccccc1.ClCCl>>CC(=O)NC(C)c1noc2cc(O)ccc12 | 48 |
CO.COC(=O)c1c(C(F)(F)F)[nH]c2c(OCc3ccccc3)cc3c(c12)C(COC(C)=O)CN3C(=O)OC(C)(C)C.O.O=C(O)CC(O)(CC(=O)O)C(=O)O.O=C([O-])[O-].[K+].[K+]>>COC(=O)c1c(C(F)(F)F)[nH]c2c(OCc3ccccc3)cc3c(c12)C(CO)CN3C(=O)OC(C)(C)C | 225 |
CO.Nc1ccc(C(=O)O)cc1O.O=S(=O)(O)O>>COC(=O)c1ccc(N)c(O)c1 | 33 |
CCO.COCCCOc1ccc(Cl)cc1[N+](=O)[O-].O.c1ccncc1>>COCCCOc1ccc(Cl)cc1N | 1 |
ClCCl.O=[Mn]=O.O=[N+]([O-])c1c(C(O)c2cccc(F)c2)ccc2cccnc12>>O=C(c1cccc(F)c1)c1ccc2cccnc2c1[N+](=O)[O-] | 59 |
CC(C)(C)S(=O)NC(CC(=O)O)c1ccc(F)c(Oc2ccccc2)c1F.CCN=C=NCCCN(C)C.CN(C)C=O.Nc1ccncc1.On1nnc2ccccc21>>CC(C)(C)S(=O)NC(CC(=O)Nc1ccncc1)c1ccc(F)c(Oc2ccccc2)c1F | 365 |
CC(=O)O.ClI.Nc1c(F)cccc1F.O.c1ccncc1>>Nc1c(F)cc(I)cc1F | 466 |
BrCC=CCBr.COCCOC.OCc1ccc2c(c1)OCO2.[Na]>>BrCC=CCOCc1ccc2c(c1)OCO2 | 120 |
CCO.CCc1nc2cc(C(C)=O)ccc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1.O.[BH4-].[Cl-].[NH4+].[Na+].[Na+].[OH-]>>CCc1nc2cc(C(C)O)ccc2n1-c1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 | 24 |
CCOC(=O)C(N)C=C(CCCO)CP(=O)(O)O.O>>NC(C=C(CCCO)CP(=O)(O)O)C(=O)O | 7 |
CC1NCCn2c(-c3cncnc3)ccc21.O=C(O)c1cc2ncc(Cl)cn2n1>>CC1c2ccc(-c3cncnc3)n2CCN1C(=O)c1cc2ncc(Cl)cn2n1 | 663 |
CCOC(=O)[C@@H]1C[C@H]1c1cc(F)c(NCc2cccc(Oc3ccccc3)c2)cc1F.CO.[Na+].[OH-]>>O=C(O)[C@@H]1C[C@H]1c1cc(F)c(NCc2cccc(Oc3ccccc3)c2)cc1F | 7 |
C1CCOC1.Cc1ccc(-c2c(NS(=O)(=O)C=Cc3ccccc3)ncnc2OCCO)cc1.Clc1ncccn1.[H-]~[Na+]>>Cc1ccc(-c2c(NS(=O)(=O)C=Cc3ccccc3)ncnc2OCCOc2ncccn2)cc1 | 37 |