text
stringlengths 25
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int64 0
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|---|---|
C1CCOC1.CCCCCC.CN(C)CCN(C)CCN(C)C.Cl.Fc1ccc(Oc2ccccc2)cc1.O=C=O.[Li]CCCC>>O=C(O)c1cc(Oc2ccccc2)ccc1F | 387 |
C1CCOC1.CO.COC(=O)C(C)C1=CCc2cc(OC)ccc21.O.[Na+].[OH-]>>COc1ccc2c(c1)CC=C2C(C)C(=O)O | 88 |
CCCCCCCCCCCCCCCCBr.CN(C)C=O.O=Cc1ccc(O)cc1>>CCCCCCCCCCCCCCCCOc1ccc(C=O)cc1 | 75 |
CCOC(=O)CNc1ccc(C(=O)c2c(-c3ccccc3)c(OC)c3ccccn23)cc1OC.COc1cc(C(=O)c2c(C)c(OC)c3ccccn23)ccc1NCC(=O)O.[Na+]~[OH-]>>COc1cc(C(=O)c2c(-c3ccccc3)c(OC)c3ccccn23)ccc1NCC(=O)O | 7 |
C1CCOC1.CCCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CC(C)(C)O2)C(=O)OC.Cl.O.O~[Li+]~[OH-]>>CCCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)NS(=O)(=O)c1c(C)c(C)c2c(c1C)CC(C)(C)O2)C(=O)O | 88 |
CCCc1nc2cnc3cc(O)ccc3c2s1.CN(C)C=O.O=C(CBr)N1CCOCC1.O=C([O-])[O-].[Cs+].[Cs+]>>CCCc1nc2cnc3cc(OCC(=O)N4CCOCC4)ccc3c2s1 | 778 |
CC(C)=O.Cc1ccc(C(=O)CBr)cc1.O=C([O-])[O-].OCc1cc(Br)ccc1O.[K+].[K+]>>Cc1ccc(C(=O)COc2ccc(Br)cc2CO)cc1 | 221 |
C1[NH2+]CC12COC2~C1[NH2+]CC12COC2~O=C([O-])C(=O)[O-].Cn1nnc(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)O)cn2)cn1>>Cn1nnc(-c2ccccc2F)c1-c1cn(-c2ccc(C(=O)N3CC4(COC4)C3)cn2)cn1 | 256 |
CC(C)(C)OC(=O)N1CC[C@@H](CO)C1.CCN(CC)CC.CS(=O)(=O)Cl.ClCCl.O=C(O)CC(O)(CC(=O)O)C(=O)O>>CC(C)(C)OC(=O)N1CC[C@@H](COS(C)(=O)=O)C1 | 0 |
CCOC(C)=O.CC[O-]~[Na+].COc1cnc(Cl)c2ccc(F)cc12.CS(C)=O>>CCOc1ccc2c(Cl)ncc(OC)c2c1 | 485 |
C1COCCO1.C=Cc1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)OC)OCC1CC21.O.[Li+].[OH-]>>C=Cc1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)OCC1CC21 | 247 |
Cl.NN~O.O=C1CCCNc2ccccc21.OCCOCCO.[K+]~[OH-]>>c1ccc2c(c1)CCCCN2 | 92 |
C1CCOC1.COC(=O)c1cc(Br)c(Br)o1.Cl.[Li+].[OH-]>>O=C(O)c1cc(Br)c(Br)o1 | 152 |
CCO.COc1ccc(Nc2ccc(OCc3ccccc3)cc2)c(CO)c1.[Pd]>>COc1ccc(Nc2ccc(O)cc2)c(CO)c1 | 698 |
CC(C)NC(=O)c1cn(COCC[Si](C)(C)C)c2ncc(-c3nn(C4CNC4)c4cc(F)ccc34)nc12.ClCCl.NCCN.O=C(O)C(F)(F)F>>CC(C)NC(=O)c1c[nH]c2ncc(-c3nn(C4CNC4)c4cc(F)ccc34)nc12 | 981 |
CC(O)c1ccsc1.ClC(Cl)(Cl)Cl.O=C1CCC(=O)N1Br>>CC(O)c1ccsc1Br | 807 |
CC(C)(C)NC(=O)c1cccc(CN2CCNCC2)c1.CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1.CCN(CC)CC.COc1cc(N)ccc1C(=O)O.ClCCl>>COc1cc(N)ccc1C(=O)N1CCN(Cc2cccc(C(=O)NC(C)(C)C)c2)CC1 | 44 |
CN1CCNCC1.COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCN(C)CC2)ccc1NC(=O)c1cccc2[nH]c(Cl)nc12>>COc1cc(C(=O)N(C)c2ccc(C)cc2OCCCCCC(=O)N2CCN(C)CC2)ccc1NC(=O)c1cccc2[nH]c(N3CCN(C)CC3)nc12 | 36 |
CC1(C)OC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21.CI.CN(C)C=O.O.O=C([O-])[O-].[K+].[K+]>>Cn1c(C#N)ccc1-c1ccc2c(c1)C(C)(C)OC(=O)N2 | 191 |
CO.C[Si](C)(C)C#Cc1ncc2c(n1)n(C1CCOCC1)c(=O)n2COCC[Si](C)(C)C.O=C([O-])[O-].[K+].[K+]>>C#Cc1ncc2c(n1)n(C1CCOCC1)c(=O)n2COCC[Si](C)(C)C | 337 |
C1CCOC1.CC(=O)OCc1cc(NC(=O)OC(C)(C)C)c([N+](=O)[O-])cc1C(F)(F)F.CO.[Na+]~[OH-]>>CC(C)(C)OC(=O)Nc1cc(CO)c(C(F)(F)F)cc1[N+](=O)[O-] | 497 |
BrBr.Cl.ClC(Cl)(Cl)Cl.N#Cc1ccc2c(c1)CCCC2>>N#Cc1cc(Br)c2c(c1)CCCC2 | 98 |
CNCc1ccccc1OC.O=C(O)CCCSc1ccc(F)cc1>>COc1ccccc1CN(C)C(=O)CCCSc1ccc(F)cc1 | 633 |
C1COCCO1.Cc1cc(Nc2cccc(N)c2)nc(N)n1.N.O.O=C(Cl)c1ccc([N+](=O)[O-])cc1.c1ccncc1>>Cc1cc(Nc2cccc(NC(=O)c3ccc([N+](=O)[O-])cc3)c2)nc(N)n1 | 11 |
CC(C)=O.CCN(CC)CC.CN(C)C=O.Cc1cc(=O)[nH]c2ccc(OCCCCl)cc12.O=C([O-])O~[Na+].[I-]~[Na+].c1ccc(CC2CCNCC2)cc1>>Cc1cc(=O)[nH]c2ccc(OCCCN3CCC(Cc4ccccc4)CC3)cc12 | 138 |
CN(CC(=O)c1ccc(F)cc1)S(=O)(=O)c1ccc(Br)s1.[BH4-]~[Na+]>>CN(CC(O)c1ccc(F)cc1)S(=O)(=O)c1ccc(Br)s1 | 24 |
CN(C)C=O.COC(=O)CCCCCBr.O.[N-]=[N+]=[N-].[Na+]>>COC(=O)CCCCCN=[N+]=[N-] | 622 |
C1CC(NC2CC2)CCN1.CCN=C=NCCCN(C)C.CN(C)C=O.Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CCC(=O)O.O=C([O-])O.On1nnc2ccccc21.[Na+]>>Cc1[nH]c(/C=C2\C(=O)Nc3ccc(S(=O)(=O)Cc4c(Cl)cccc4Cl)cc32)c(C)c1CCC(=O)N1CCC(NC2CC2)CC1 | 146 |
CCO.CCOCC.Cl.O=Cc1ccc(F)c(Oc2ccccc2)c1.[BH4-].[Na+]>>OCc1ccc(F)c(Oc2ccccc2)c1 | 356 |
CCN(CC)CC.CN(C)C(On1nnc2cccnc21)=[N+](C)C~F[P-](F)(F)(F)(F)F.CN(C)C=O.CO[C@H]1CCNC1~Cl.O.O=C(O)C1CCN(c2cncnc2-c2ccc(F)cc2)CC1>>CO[C@H]1CCN(C(=O)C2CCN(c3cncnc3-c3ccc(F)cc3)CC2)C1 | 146 |
CN(C)/C=C/C(=O)c1nn(-c2cccc(OC(F)(F)F)c2)ccc1=O.NNc1ccc(F)cc1>>O=c1ccn(-c2cccc(OC(F)(F)F)c2)nc1-c1ccnn1-c1ccc(F)cc1 | 984 |
C1CCOC1.CCOCC.COC(=O)CCCCCCCC(=O)O.O.O=C([O-])[O-]~[K+]~[K+]>>COC(=O)CCCCCCCCO | 231 |
CC1(C)CCC(C)(C)c2cc(-c3nc(C4CCNCC4)co3)ccc21.Cl.O=CCCCCO>>CC1(C)CCC(C)(C)c2cc(-c3nc(C4CCN(CCCCCO)CC4)co3)ccc21 | 484 |
CCCS(=O)(=O)Nc1ccc(Cl)c(NC(=O)Nc2cc(Cl)ncn2)c1F.CCN(C(C)C)C(C)C.ClCCCl.NCc1ccccc1>>CCCS(=O)(=O)Nc1ccc(Cl)c(NC(=O)Nc2cc(NCc3ccccc3)ncn2)c1F | 165 |
C1COCCO1.CC(C)(C)OC(=O)OC(=O)OC(C)(C)C.Nc1nc2c(s1)CNCC2.O.O=C([O-])[O-]~[K+]~[K+]>>CC(C)(C)OC(=O)N1CCc2nc(N)sc2C1 | 694 |
CC#N.NCCCCN1CCOCC1.O=C([O-])[O-].O=[N+]([O-])c1ccc(F)c(F)c1.[K+].[K+]>>O=[N+]([O-])c1ccc(NCCCCN2CCOCC2)c(F)c1 | 572 |
CCN(CC)CC.CSc1ncc(C#N)c(Cl)n1.ClCCl.NC1CC2CCC1C2>>CSc1ncc(C#N)c(NC2CC3CCC2C3)n1 | 166 |
CCN(C(C)C)C(C)C.CCOC(=O)C(C#N)=NOC(N1CCOCC1)=[N+](C)C~F[P-](F)(F)(F)(F)F.CN(C)C=O.COc1cc(C)[nH]c(=O)c1C[NH3+]~[Cl-].Cc1c(C(=O)O)c2ccccc2n1[C@H](C)C1CCN(CC(C)(F)F)CC1>>COc1cc(C)[nH]c(=O)c1CNC(=O)c1c(C)n([C@H](C)C2CCN(CC(C)(F)F)CC2)c2ccccc12 | 674 |
C1=CCCCC1.CC#N.CCN=C=NCCCN(C)C.Cc1cc(C(=O)O)cc(Cl)n1.NN~O.On1nnc2ccccc21>>Cc1cc(C(=O)NN)cc(Cl)n1 | 55 |
CN1CCNCC1.O=C([O-])[O-].O=[N+]([O-])c1ccc(Cl)nc1.[K+].[K+]>>CN1CCN(c2ccc([N+](=O)[O-])cn2)CC1 | 220 |
CC(C)(C)OC(=O)N1CCC(COCC(NC(=O)c2ccc3cc[nH]c3c2)c2ccc(F)cc2)CC1.COc1ccccc1>>O=C(NC(COCC1CCNCC1)c1ccc(F)cc1)c1ccc2cc[nH]c2c1 | 575 |
CI.CN(C)C=O.Nc1cc(Br)cc(C(F)(F)F)c1C(=O)O.O.O=C([O-])[O-].[Cs+].[Cs+]>>COC(=O)c1c(N)cc(Br)cc1C(F)(F)F | 415 |
CC#N.Cc1c(O)cccc1Cl.NC(=O)c1cc(-c2ccc(CBr)cc2)no1.O=C([O-])[O-].[K+].[K+]>>Cc1c(Cl)cccc1OCc1ccc(-c2cc(C(N)=O)on2)cc1 | 127 |
C1COCCO1.CCCCC(CC(=O)OCC)c1sc2cc(OC)ccc2c1C.O.[K+].[OH-]>>CCCCC(CC(=O)O)c1sc2cc(OC)ccc2c1C | 7 |
C1CCOC1.CCOC(=O)c1ccc(CC(=O)OC(C)(C)C)o1.Cl.[Na+]~[OH-]>>CC(C)(C)OC(=O)Cc1ccc(C(=O)O)o1 | 171 |
CCO.CCOC(=O)c1cc(C(F)(F)F)nn1-c1cccc(C#N)c1.Cl.O.O=[Pt].[H][H].[Pd]>>CCOC(=O)c1cc(C(F)(F)F)nn1-c1cccc(CN)c1 | 175 |
C1CCOC1.CO.COC(=O)C(C)(C)C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1.O.[Li+].[Li]O.[OH-]>>CC(C)(C(=O)O)C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 | 361 |
CC(C)=O.CCOC(=O)CBr.COc1ccc(Cl)cc1O.O=C([O-])[O-].[Cs+].[Cs+]>>CCOC(=O)COc1cc(Cl)ccc1OC | 123 |
CCO.O=C(O)C1CCC(O)CC1.O=C([O-])[O-].O=S(=O)(O)O.[Na+].[Na+]>>CCOC(=O)C1CCC(O)CC1 | 17 |
C1CCOC1.CC(=O)O[BH-](OC(C)=O)OC(C)=O~[Na+].CC(C)(C)OC(=O)N1CCCC(c2ccn(-c3ccc4[nH]nc(-c5ccncc5)c4c3)n2)C1.COc1cccc(F)c1C=O>>COc1cccc(F)c1CN1CCCC(c2ccn(-c3ccc4[nH]nc(-c5ccncc5)c4c3)n2)C1 | 935 |
CCO.NN.O.O=C1c2ccccc2C(=O)N1CCOc1n[nH]c2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12>>NCCOc1n[nH]c2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12 | 242 |
COc1ccc([N+](=O)[O-])c(C(=O)O)c1OCc1ccccc1.O.[NH4+].[OH-]>>COc1ccc(N)c(C(=O)O)c1OCc1ccccc1 | 202 |
CCOC(=O)Cc1ccc(NC)cc1.O=C(Cl)CCl>>CCOC(=O)Cc1ccc(N(C)C(=O)CCl)cc1 | 160 |
CO.COC(=O)CCCCN=[N+]=[N-].O.[K+].[OH-]>>[N-]=[N+]=NCCCCC(=O)O | 88 |
OB(O)c1cccc(Cl)c1.Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Br>>Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1cccc(Cl)c1 | 872 |
CCN(CC)CC.CN(C)C=O.CN(C)[P+](On1nnc2ccccc21)(N(C)C)N(C)C~F[P-](F)(F)(F)(F)F.COCc1ccc(C(=O)O)c(N)n1.Cc1cccc(Oc2cccc(CN)c2)c1.O>>COCc1ccc(C(=O)NCc2cccc(Oc3cccc(C)c3)c2)c(N)n1 | 790 |
BrC1CCC1.CN(C)C=O.COCOc1ccc(Br)cc1O.O.O=C([O-])[O-].[K+].[K+]>>COCOc1ccc(Br)cc1OC1CCC1 | 153 |
CO.Cn1cnc(-c2cc3nccc(Oc4ccc([N+](=O)[O-])cc4F)c3s2)c1.O.[Cl-].[Fe].[NH4+]>>Cn1cnc(-c2cc3nccc(Oc4ccc(N)cc4F)c3s2)c1 | 335 |
CCO.COC(=O)c1c(C)noc1C(=O)NC(C)C.Cl.O.[K+].[OH-]>>Cc1noc(C(=O)NC(C)C)c1C(=O)O | 152 |
CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2O)c1.CCOC(C)=O.CN(C)C=O.Fc1ccc(CBr)cc1.O=C([O-])[O-]~[K+]~[K+]>>CCOC(=O)c1cccc(-n2c(C)ccc2-c2cc(S(C)(=O)=O)ccc2OCc2ccc(F)cc2)c1 | 127 |
CNC1(C(N)=O)CCNCC1.COCCBr>>CNC1(C(N)=O)CCN(CCOC)CC1 | 73 |
C1CCOC1.CC(=O)O[BH-](OC(C)=O)OC(C)=O.N#Cc1ccccc1-c1cc(-c2ccsc2C=O)cn(-c2ccccc2)c1=O.O=C([O-])[O-].[Na+].[Na+].[Na+]>>N#Cc1ccccc1-c1cc(-c2ccsc2CO)cn(-c2ccccc2)c1=O | 529 |
CCO.CON(C)C(=O)c1ccc([N+](=O)[O-])c(NC2CCCC2)c1.O=C[O-]~[NH4+]>>CON(C)C(=O)c1ccc(N)c(NC2CCCC2)c1 | 28 |
CC(C)(C)[O-].CC(C)Oc1cccc(OC(C)C)c1-c1ccccc1P(C1CCCCC1)C1CCCCC1.Cc1ccccc1.Cl.O.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=C(/C=C/c1ccccc1)/C=C/c1ccccc1.O=S(=O)(c1cccs1)N1CCNC(CC2CCOCC2)C1.OC(c1ccc(Br)cc1)(C(F)(F)F)C(F)(F)F.[Na+].[Pd].[Pd]>>O=S(=O)(c1cccs1)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)C(CC2CCOCC2)C1 | 294 |
C1CCOC1.CI.O=C1c2cccc([N+](=O)[O-])c2C2CC(O)CCN12>>COC1CCN2C(=O)c3cccc([N+](=O)[O-])c3C2C1 | 140 |
CC(C)(C)[Si](C)(C)Oc1ccccc1C=O.CO.[BH4-]~[Na+]>>CC(C)(C)[Si](C)(C)Oc1ccccc1CO | 356 |
BrCc1ccccc1.C1CCOC1.CCCc1nc2onc(C)c2c(=O)[nH]1.C[Si](C)(C)[N-][Si](C)(C)C~[Li+].[I-]~[Na+]>>CCCc1nc2onc(C)c2c(=O)n1Cc1ccccc1 | 389 |
BrB(Br)Br.COc1cc(Br)ccc1Cl.ClCCl>>Oc1cc(Br)ccc1Cl | 48 |
CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(-c3c(Cl)cc(N)cc3C(F)(F)F)cc2)CC1.Cl.ClCCl.O.O=C([O-])[O-].S=C(Cl)Cl.[Ca+2]>>CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccc(-c3c(Cl)cc(N=C=S)cc3C(F)(F)F)cc2)CC1 | 114 |
CCOC(C)=O.CN(C)C=O.Cc1ccc(S(=O)(=O)Cl)cc1.Fc1cccc2[nH]ccc12.[H-].[Na+]>>Cc1ccc(S(=O)(=O)n2ccc3c(F)cccc32)cc1 | 648 |
CC(C)(C)[Si](C)(C)Cl.ClCCl.Oc1ccc2[nH]ccc2c1.c1c[nH]cn1>>CC(C)(C)[Si](C)(C)Oc1ccc2[nH]ccc2c1 | 746 |
CC(=O)Cl.CCOCC.CO.O=C(O)[C@H]1C[C@H](O)CN1>>COC(=O)[C@H]1C[C@H](O)CN1 | 195 |
C1CCOC1.CC(C)(C)[Si](C)(C)Oc1ccc2ccc(I)cc2c1.CCCC[N+](CCCC)(CCCC)CCCC.CCOC(C)=O.O.[F-]>>Oc1ccc2ccc(I)cc2c1 | 754 |
CCOC(C)=O.O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(C#CCCO)cc2c1O.c1ccncc1>>O=C(NCc1ccc(Cl)cc1)c1cnc2c(F)cc(CCCCO)cc2c1O | 717 |
CCOC(=O)CC[C@H](N)C(=O)OCC.Nc1nc(=O)c2c(CCc3ccc(C(=O)O)cc3)c[nH]c2[nH]1>>CCOC(=O)CC[C@H](NC(=O)c1ccc(CCc2c[nH]c3[nH]c(N)nc(=O)c23)cc1)C(=O)OCC | 709 |
C1CCOC1.COC(=O)c1cc(CN2CCOCC2)c(Br)cc1O.O.[Li+]~[OH-]>>O=C(O)c1cc(CN2CCOCC2)c(Br)cc1O | 247 |
CCO.ClCc1nc2ccccc2[nH]1.O=C([O-])[O-].[K+].[K+].c1ccc(OCC2CNCCO2)cc1>>c1ccc(OCC2CN(Cc3nc4ccccc4[nH]3)CCO2)cc1 | 257 |
Cc1ccc2ocnc2c1.ClC(Cl)(Cl)Cl.O=C(OOC(=O)c1ccccc1)c1ccccc1.O=C1CCC(=O)N1Br>>BrCc1ccc2ocnc2c1 | 29 |
CC(=O)Nc1nc2ccc(Oc3cccc(N)c3)cc2s1.CC(C)(C#N)Oc1cccc(C(=O)O)c1.CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F.O.c1ccncc1>>CC(=O)Nc1nc2ccc(Oc3cccc(NC(=O)c4cccc(OC(C)(C)C#N)c4)c3)cc2s1 | 50 |
CN1CCCN(C)C1=O.ClCCl.OCc1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1.[Mn+4].[O-2].[O-2]>>O=Cc1cc2c(Nc3cccc(Cl)c3)ncnc2[nH]1 | 263 |
C[C@H]1C[C@H](N2CCCC2)CCN1.Cc1nn(-c2cccc(C(F)(F)F)c2)c(C2CC2)c1C(=O)O.Cl.Cl>>Cc1nn(-c2cccc(C(F)(F)F)c2)c(C2CC2)c1C(=O)N1CC[C@@H](N2CCCC2)C[C@@H]1C | 733 |
C1CCOC1.CO.COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)c2cc3ncccc3n2C)C(=O)OCc2ccccc2)cc1.[OH-]~[OH-]~[Pd+2]>>COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)c2cc3ncccc3n2C)C(=O)O)cc1 | 186 |
C1CCOC1.CCOC(=O)CCc1ccc(OCOC)cc1Oc1ccc(C(F)(F)F)cn1.Cl.[Na+]~[OH-]>>CCOC(=O)CCc1ccc(O)cc1Oc1ccc(C(F)(F)F)cn1 | 755 |
CC(=O)Cl.CCO.O=C(O)CCCCCCCCCCCO>>CCOC(=O)CCCCCCCCCCCO | 47 |
COc1ccccc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1.O=S(=O)(O)Cl>>COc1ccc(S(=O)(=O)Cl)cc1N1CCN(C(=O)C(Cl)(Cl)Cl)CC1 | 182 |
CI.CN(C)C=O.O=C1CC2(CCC(n3cc(Br)cn3)CC2)CN1.[H-].[Na+]>>CN1CC2(CCC(n3cc(Br)cn3)CC2)CC1=O | 83 |
CCCCCC~CCOC(C)=O.Cc1ccc(N(C)S(C)(=O)=O)c(CO)c1.ClC(Cl)Cl.O=S(Cl)Cl>>Cc1ccc(N(C)S(C)(=O)=O)c(CCl)c1 | 81 |
C1CCOC1~CCO.COc1ccc(CCNc2nccc(-c3cccc([N+](=O)[O-])c3)n2)cc1OC.[C]~[Pd]>>COc1ccc(CCNc2nccc(-c3cccc(N)c3)n2)cc1OC | 1 |
CC(=O)O.COc1cc(NC(=O)CC23CC4CC(CC(C4)C2)C3)c(C)c(OC)c1>>Cc1c(O)cc(O)cc1NC(=O)CC12CC3CC(CC(C3)C1)C2 | 20 |
CC(C)(C)C(=O)Cl.CCN(CC)CC.CCOCC.Nc1ccc2c(c1)OCCO2>>CC(C)(C)C(=O)Nc1ccc2c(c1)OCCO2 | 134 |
C1CCOC1.CCCc1cc2cc(I)cc(COc3ccc(CCC(=O)OCC)c(C)c3C)c2o1.O.[Li+]~[OH-]>>CCCc1cc2cc(I)cc(COc3ccc(CCC(=O)O)c(C)c3C)c2o1 | 7 |
CCN(C(C)C)C(C)C.CCOC(=O)C(C)(C)N1CCC(NCc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)CC1.CN(C)C(On1nnc2cccnc21)=[N+](C)C.CN(C)C=O.F[P-](F)(F)(F)(F)F.O=C(O)Cn1c(CCc2cccc(F)c2F)nc(=O)c2cccnc21>>CCOC(=O)C(C)(C)N1CCC(N(Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)C(=O)Cn2c(CCc3cccc(F)c3F)nc(=O)c3cccnc32)CC1 | 633 |
CCCn1cnc2[nH]ccc2c1=O.COCCOC.O=C(c1ccc(Cl)cc1)c1ccc(CBr)cc1.[H-].[Na+]>>CCCn1cnc2c(ccn2Cc2ccc(C(=O)c3ccc(Cl)cc3)cc2)c1=O | 389 |
C1CC(N2CCC(OC3CCNCC3)CC2)C1.CS(C)=O.N#Cc1ccc(F)c(F)c1.O=C([O-])[O-].[K+].[K+]>>N#Cc1ccc(N2CCC(OC3CCN(C4CCC4)CC3)CC2)c(F)c1 | 26 |
CC(C)Br.O=C([O-])[O-].Oc1ccccc1Br.[K+].[K+]>>CC(C)Oc1ccccc1Br | 153 |
C1COCCO1.COC(=O)c1ccc(C(CC(=O)c2ccc(OC)nc2)c2ccccc2Cl)cc1F.Cl>>COC(=O)c1ccc(C(CC(=O)c2ccc(=O)[nH]c2)c2ccccc2Cl)cc1F | 758 |
CC(C)Nc1ccccc1[N+](=O)[O-].CCO.O=C[O-]~[NH4+].[Pd]>>CC(C)Nc1ccccc1N | 1 |
C=CCOc1cc(-n2c(=O)cc(C(F)(F)F)[nH]c2=O)c(F)cc1Br.CI.CN(C)C=O.O=C([O-])[O-].[K+].[K+]>>C=CCOc1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Br | 570 |
CC(C)NCC(=O)c1cc(F)c(N)c(Cl)c1~Cl.Cl.[BH4-]~[Na+]>>CC(C)NCC(O)c1cc(F)c(N)c(Cl)c1 | 24 |
C1CCN(C2CCNCC2)CC1.CCN(CC)CC.CCN=C=NCCCN(C)C.CCOc1cccc(Cn2ncc3c(N4CCC(C(=O)O)CC4)ncnc32)c1.Cl.Cl.ClC(Cl)Cl.O=C([O-])O.On1nnc2ccccc21.[Na+]>>CCOc1cccc(Cn2ncc3c(N4CCC(C(=O)N5CCC(N6CCCCC6)CC5)CC4)ncnc32)c1 | 146 |