Datasets:
seq
stringlengths 43
49
| label
int64 0
1
|
---|---|
YYAMYREISTNTYESNLYLRYDSYTWAEWAYLWY|GAGGAGGGV | 0 |
YSAMYEEKVAHTDENIAYLMFHYYTWAVQAYTGY|EYGIFNQKI | 1 |
YHTEYREICAKTDEDTLYLNYHHYTWAVLAYEWY|IRLPETIDL | 1 |
YHTEYREICAKTYENTAYLNYHDYTWAVLAYEWY|KRTFRKFTY | 1 |
YYAMYGEKVAHTHVDTLYLRYHYYTWAVWAYTWY|YLDHEQRDPF | 0 |
YYAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|FKGSGYWQW | 0 |
YDSGYREKYRQADVNKLYLWYDSYTWAEWAYTWY|QSLRGVPHV | 0 |
YDSGYREKYRQADVNKLYLWYDSYTWAEWAYTWY|HYNNQIRTL | 1 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYEWY|FLKDVMESM | 1 |
YYSEYRNICTNTDESNLYLRYNFYTWAVLTYTWY|EHTPDDPLL | 1 |
YYTMYREISTNTYENTAYWTYNLYTWAVLAYEWY|TKAFAEPSL | 0 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|AMLPDLQPLEKL | 1 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|AKRDAHRSLG | 0 |
YYAMYGEKVAHTHVDTLYLRYHYYTWAVWAYTWY|RLAVYIDKV | 1 |
YYSEYRNICTNTDESNLYLWYNFYTWAELAYTWH|YQIANIYEL | 1 |
YYAGYREKYRQTDVSNLYIRYDYYTWAELAYLWY|TSQWVSYTI | 0 |
YYAMYRNNVAQTDVDTLYIRYHYYTWAVWAYTWY|LTSVDIETA | 1 |
YYSEYRNIYAQTDESNLYLSYDYYTWAERAYEWY|YEAFPKPEH | 0 |
YHTEYREICAKTDEDTLYLNYHDYTWAVLAYEWY|ERALTYARGETL | 1 |
YDSGYRENYRQADVSNLYLRYDSYTLAALAYTWY|FADFCMGLYL | 0 |
YHTEYREICAKTDEDTLYLNYHDYTWAVLAYEWY|RRLEWERIR | 1 |
YHSTYRNISTNTDESNLYLRYDSYTWAVLAYTWH|EEFADFATF | 1 |
YSAGYREKYRQADVNKLYLRFNFYTWAERAYTWY|VLDDKDYFLF | 1 |
YHTKYREISTNTYESNLYLRYNYYSLAVLAYEWY|TEILGTQEI | 1 |
YYATYRNIFTNTYENIAYWTYNYYTWAELAYLWH|FYRHKLLKW | 0 |
YYSEYRNICTNTDESNLYLRYNFYTWAVLTYTWY|FHDMMPKYL | 1 |
YYAGYRENYRQTDVNKLYIRYDLYTWAELAYTWY|HPTYNISHP | 0 |
YHTKYREISTNTYESNLYWRYNLYTWAVDAYLSY|MQLVDTKAG | 0 |
YFAMYQENVAHTDESIAYIMYQDYTWAVLAYTWY|AASPAPASA | 0 |
YHTEYRNICAKTDVGNLYWTYNFYTWAVLAYEWH|VTTSTKASS | 0 |
YYAMYREISTNTYESNLYLRYDSYTWAEWAYLWY|RMFLAMITY | 1 |
YYSEYRNIYAQTDESNLYLSYDYYTWAERAYEWY|EPSGNNYHIL | 1 |
YYTKYREISTNTYENTAYIRYDDYTWAVDAYLSY|LMNILKSIT | 0 |
YHTEYREICAKTDESTLYLNYHDYTWAELAYEWY|QFVMKTRRT | 0 |
YDSGYREKYRQADVSNLYFRYDFYTLAADAYTWY|ISLTRPGSS | 0 |
YYAMYGENMASTYENIAYIVYNYYTWAVLAYLWY|FSLKGVDFQKF | 1 |
YYATYRNIFTNTYESNLYIRYDFYTWAVLAYLWY|GKKPYKCEE | 0 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|LFWFGRRFE | 0 |
YYATYRNIFTNTYESNLYIRYDSYTWAVRAYLWY|YPIVQYDVY | 1 |
YYTKYREISTNTYENTAYIRYDDYTWAVLAYLSY|AWTGPGCWHE | 0 |
YDSGYREKYRQADVNKLYLWYDSYTWAEWAYTWY|LLQPQDVGD | 0 |
YDSEYRNIFTNTDESNLYLSYNYYTWAVDAYTWY|SSKSSHCDS | 0 |
YSAMYEEKVAHTDENIAYLMFHYYTWAVQAYTGY|PYGPPPTGL | 1 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|MMIMIKFMGV | 1 |
YSAMYEEKVAHTDENIAYLMFHYYTWAVQAYTGY|QLACHHRLHT | 0 |
YYAGYREKYRQTDVNKLYLRYNFYTWAERAYTWY|CGESIDRN | 0 |
YHSTYRNISTNTYESNLYLRYDSYTWAVLAYTWH|YEDTLREMF | 1 |
YYAMYQENVAQTDVDTLYIIYRDYTWAAQAYRWY|GSKFKELVTH | 0 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAEWAYTWY|RILGAGCFV | 1 |
YYATYGENMASTYENIAYIRYDSYTWAVLAYLWY|VTAADTAVYY | 1 |
YYAMYREISTNTYESNLYLRYDSYTWAEWAYLWY|CTNPGTRYC | 0 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|TLTDQDLKELG | 0 |
YYATYGENMASTYENIAYIRYDSYTWAVLAYLWY|RRAFCESDKTC | 0 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVQAYTGY|EWKEFVWNP | 0 |
YYAMYGENMASTYENIAYIVYDSYTWAVLAYLWY|HLSKSMMEA | 0 |
YYAMYRNNVAHTDANTLYIRYQDYTWAEWAYRWY|EIPLQWIASA | 1 |
YFAMYGEKVAHTHVDTLYLRYHYYTWAVWAYTWY|LIDSTPYRQ | 0 |
YYATYGENMASTYENIAYIRYDSYTWAVLAYLWY|ERSWNSGHEW | 1 |
YYAMYREISTNTYESNLYLRYDSYTWAEWAYLWY|KINKKRIAL | 1 |
YYTKYREISTNTYENTAYIRYDDYTWAVLAYLSY|PPCESACTV | 0 |
YYAMYRNNVAQTDVDTLYIMYRDYTWAVWAYTWY|RSNLGWLCL | 0 |
YYAMYGENMASTYENIAYIVYDSYTWAVLAYLWY|TLRCWALSF | 0 |
YFAMYQENVAHTDESIAYIMYQDYTWAVLAYTWY|VTLPYFHSF | 1 |
YYAMYREISTNTYESNLYLRYDSYTWAEWAYLWY|LRFPGQLNAD | 0 |
YYAMYGENMASTYENIAYIVYDSYTWAVLAYLWY|KLATTILQHW | 1 |
YYSEYRNICTNTDESNLYLWYNFYTWAELAYTWH|LPYKGGNTL | 1 |
YHTEYREICAKTDESTLYLNYHDYTWAELAYEWY|RRLSVLVDDY | 1 |
YHSTYREISTNTYEDTLYIRSNFYTWAVDAYTWY|KEINQNVEI | 1 |
YFAMYGEKVAHTHVDTLYVRCHYYTWAVLAYTWY|GLDAIVTQL | 1 |
YYAMYQENVAQTDVDTLYIIYRDYTWAAQAYRWY|LTMFLIAENK | 1 |
YFAMYQENVAQTDVDTLYIIYRDYTWAELAYTWY|GMTGYGMPR | 1 |
YHTEYREICAKTDESTLYLNYDYYTWAELAYEWY|PRVQNRVKSM | 0 |
YYAMYQENVAQTDVDTLYIIYRDYTWAAQAYRWY|PAPTASPPP | 0 |
YDSEYRNIFTNTDESNLYLSYNYYTWAVDAYTWY|DDGNDVSPY | 0 |
YYAMYQENVAQTDVDTLYIIYRDYTWAAQAYRWY|SWPWVRTLL | 0 |
YYAGYREKYRQTDVNKLYLRYNFYTWAERAYTWY|ALDTSNVMV | 1 |
YYTMYREISTNTYENTAYWTYNLYTWAVLAYEWY|AGPGGCSFP | 0 |
YHTKYREISTNTYESNLYLRYNYYSLAVLAYEWY|FEQFPPPEI | 1 |
YSAMYEEKVAHTDENIAYLMFHYYTWAVLAYTGY|EYNKSWQTF | 1 |
YFAMYQENMAHTDANTLYIIYRDYTWVARVYRGY|SQLPEEPET | 0 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVLAYTWY|LWQRPWLR | 0 |
YYATYGENMASTYENIAYIRYDSYTWAVLAYLWY|IAAQRTINW | 1 |
YFAMYGEKVAHTHVDTLYVRYHYYTWAVQAYTGY|INSLSSEMH | 0 |
YYATYGENMASTYENIAYIRYDSYTWAVLAYLWY|VSANVKGNW | 1 |
YYAMYGENMASTYENIAYIVYNYYTWAVLAYLWY|YSPKAEELLS | 0 |
YSAMYEEKVAHTDENIAYLMFHYYTWAVLAYTGY|REIPARQSR | 0 |
YFAMYGEKVAHTHVDTLYVMYHYYTWAVLAYTWY|KKLFLVNNK | 0 |
YYAMYQENVAQTDVDTLYIIYRDYTWAAQAYRWY|SVYDGEEHGR | 1 |
YSAMYEEKVAHTDENIAYLMFHYYTWAVQAYTGY|GRDYSMVESP | 0 |
YYSEYRNIYAQTDESNLYLSYDYYTWAERAYEWY|LHSNSTRMALFA | 0 |
YYAGYREKYRQTDVNKLYLRYNFYTWAERAYTWY|TKPIWTRNP | 0 |
YDSGYREKYRQADVNKLYLWYDSYTWAEWAYTWY|WSWTKNRMWRK | 0 |
YYAGYREKYRQTDVSNLYLRYNFYTWAERAYTWY|FVNDIFERI | 1 |
YYAGYREKYRQTDVSNLYLRYNFYTWAERAYTWY|TAAPPAQPL | 1 |
YYAMYREISTNTYESNLYLRYDSYTWAEWAYLWY|QLFSSQYPFHVPL | 1 |
YYAGYRNIYAQTDESNLYWTYNLYTWAVLAYTWY|EAFSIPGVLEA | 1 |
YHTEYREICAKTDESTLYLNYHDYTWAELAYEWY|IEDLYTERG | 0 |
YHTEYREICAKTDEDTLYLNYHDYTWAVLAYEWY|RKSLRTDFR | 1 |
YYAGYREKYRQTDVSNLYIRYDYYTWAELAYLWY|AADMLGLSL | 0 |
YYAMYGENMASTYENIAYIVYDSYTWAVLAYLWY|LTGPALEAWTDR | 0 |
Dataset Card for Peptide-HLA/MHC Affinity Dataset
Dataset Summary
The human leukocyte antigen (HLA) gene encodes major histo-compatibility complex (MHC) proteins, which can bind to peptide fragments and be presented to the cell surface for subsequent T cell receptors (TCRs) recognition. Accurately predicting the interaction between peptide sequence and HLA molecule will boost the understanding of immune responses, antigen presentation, and designing therapeutic interventions such as peptide-based vaccines or immunotherapies.
Dataset Structure
Data Instances
For each instance, there is a string representing the protein sequence and an integer label indicating that whether a given paired peptide and HLA sequence can bind or not. See the peptide-HLA/MHC affinity dataset viewer to explore more examples.
{'seq':'MEHVIDNFDNIDKCLKCGKPIKVVKLKYIKKKIENIPNSHLINFKYCSKCKRENVIENL'
'label':1}
The average for the seq
and the label
are provided below:
Feature | Mean Count |
---|---|
seq | 45 |
label (0) | 0.5 |
label (1) | 0.5 |
Data Fields
seq
: a string containing the protein sequencelabel
: an integer label indicating that whether a given paired peptide and HLA sequence can bind or not.
Data Splits
The Peptide-HLA/MHC Affinity dataset has 3 splits: train, valid, and test. Below are the statistics of the dataset.
Dataset Split | Number of Instances in Split |
---|---|
Train | 57,357 |
Valid | 7,008 |
Test | 8,406 |
Source Data
Initial Data Collection and Normalization
The modeling data is from Wu et al. The raw dataset contains millions of samples, we used the same split and downsample 1% for training and 5% for validation and testing (57,357 training samples, 7,008 validation samples and 8,406 test samples).
Licensing Information
The dataset is released under the Apache-2.0 License.
Citation
If you find our work useful, please consider citing the following paper:
@misc{chen2024xtrimopglm,
title={xTrimoPGLM: unified 100B-scale pre-trained transformer for deciphering the language of protein},
author={Chen, Bo and Cheng, Xingyi and Li, Pan and Geng, Yangli-ao and Gong, Jing and Li, Shen and Bei, Zhilei and Tan, Xu and Wang, Boyan and Zeng, Xin and others},
year={2024},
eprint={2401.06199},
archivePrefix={arXiv},
primaryClass={cs.CL},
note={arXiv preprint arXiv:2401.06199}
}
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