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These results suggest that an early transition to menopause ( shortening the time of exposure to estrogens ) may influence pain hypersensitivity and could be related to aggravation of FM symptoms .
{ "id": "C0441636", "pos": [ 62, 72 ], "name": "shortening" }
{ "id": "C0014939", "pos": [ 97, 106 ], "name": "estrogens" }
0NA
Hence , autophagosomes accumulate in OCRL-depleted cells and in the kidneys of Lowe syndrome patients .
{ "id": "C0022646", "pos": [ 68, 75 ], "name": "kidneys" }
{ "id": "C0028860", "pos": [ 79, 92 ], "name": "Lowe syndrome" }
11finding_site_of
In particular , the amount of outdoor activities and near work would display an important role in the pathogenesis of the disease .
{ "id": "C0012634", "pos": [ 122, 129 ], "name": "disease" }
{ "id": "C0475806", "pos": [ 53, 57 ], "name": "near" }
0NA
In lung transplant recipients on cyclosporine therapy , the antidepressant drug nefazadone may cause increased cyclosporine levels .
{ "id": "C0010592", "pos": [ 111, 123 ], "name": "cyclosporine" }
{ "id": "C4510269", "pos": [ 33, 53 ], "name": "cyclosporine therapy" }
10direct_substance_of
dose , agitation speed and pH on the sorbed amount of IBP was studied through a 2(3 ) full factorial central composite design ( CCD ) .
{ "id": "C0085631", "pos": [ 7, 16 ], "name": "agitation" }
{ "id": "C0002658", "pos": [ 17, 22 ], "name": "speed" }
0NA
Varicella is a very common disease in Romania , which may develop complications .
{ "id": "C0012634", "pos": [ 27, 34 ], "name": "disease" }
{ "id": "C0008049", "pos": [ 0, 9 ], "name": "Varicella" }
0NA
Three of these four patients had undergone endoscopy with conscious sedation immediately before the dilation .
{ "id": "C0012359", "pos": [ 100, 108 ], "name": "dilation" }
{ "id": "C0014245", "pos": [ 43, 52 ], "name": "endoscopy" }
0NA
Single crystals have also been grown of a genetically engineered site-specific mutant for which the replacement of an arginine ( Arg-57 ) to a glycine has been shown to not only drastically affect the enzyme activity but also its kinetic mechanism ( Kuo , L. C. , Miller , A. W. , Lee , S. , and Kozuma , C. ( 1988 ) Biochemistry 27 , 8823 - 8832 ) .
{ "id": "C0427896", "pos": [ 7, 15 ], "name": "crystals" }
{ "id": "C0035139", "pos": [ 100, 111 ], "name": "replacement" }
0NA
Open synovectomy has been used since 1969 to prevent recurrent hemarthrosis of target joints .
{ "id": "C0022417", "pos": [ 86, 92 ], "name": "joints" }
{ "id": "C0018924", "pos": [ 63, 75 ], "name": "hemarthrosis" }
11finding_site_of
Histologically the tumors were similar to renal angiomyolipomas , containing tortuous blood vessels , smooth muscle , and fat .
{ "id": "C0027651", "pos": [ 19, 25 ], "name": "tumors" }
{ "id": "C1267092", "pos": [ 102, 115 ], "name": "smooth muscle" }
0NA
The current study demonstrates a higher prevalence of venous , as opposed to arterial , events in PMF , post-diagnosis , and clarifies their nature as being mostly provoked .
{ "id": "C0003842", "pos": [ 77, 85 ], "name": "arterial" }
{ "id": "C0042449", "pos": [ 54, 60 ], "name": "venous" }
0NA
In addition , as in bacteria and red blood cells , inosine and adenosine in the lens , acting as ribose donors , exert a profound effect on the process of adenine conversion into ATP .
{ "id": "C0001480", "pos": [ 179, 182 ], "name": "ATP" }
{ "id": "C0001443", "pos": [ 63, 72 ], "name": "adenosine" }
16is_modification_of
The genotoxic hepatocarcinogens dimethylnitrosamine , diethylnitrosamine , benzo[a]pyrene and 2-acetylaminofluorene , and the hepatocytotoxins bromobenzene , acetaminophen , carbon tetrachloride , chloroform and methotrexate had no effect on mouse hepatocyte intercellular communication at non-cytotoxic levels .
{ "id": "C0025677", "pos": [ 212, 224 ], "name": "methotrexate" }
{ "id": "C0000970", "pos": [ 158, 171 ], "name": "acetaminophen" }
0NA
However , patients who received tMCS had increased lengths of stays and rates of acute renal , hepatic , and respiratory failure , sepsis , bleeding complications , and surgical reoperations .
{ "id": "C0019080", "pos": [ 140, 148 ], "name": "bleeding" }
{ "id": "C1145670", "pos": [ 109, 128 ], "name": "respiratory failure" }
0NA
To determine the relationship between tophus , erosion and bone remodeling factors in gout .
{ "id": "C0018099", "pos": [ 86, 90 ], "name": "gout" }
{ "id": "C0221248", "pos": [ 38, 44 ], "name": "tophus" }
5cause_of
The success of proteasome inhibition in multiple myeloma highlights the critical role for the ubiquitin-proteasome system ( UPS ) in this disease .
{ "id": "C0334463", "pos": [ 124, 127 ], "name": "UPS" }
{ "id": "C0012634", "pos": [ 138, 145 ], "name": "disease" }
0NA
The near point-of-care/point-of-need genotyping methods reported here can be applied for detecting and assessing risks of diseases such as cancer and to detect SNPs that alter drug metabolism and hence response to therapy .
{ "id": "C0006826", "pos": [ 139, 145 ], "name": "cancer" }
{ "id": "C0012634", "pos": [ 122, 130 ], "name": "diseases" }
0NA
Patients lacked a cervix ( cervical agenesis ) or had one of three variants of cervical dysgenesis .
{ "id": "C0007874", "pos": [ 18, 24 ], "name": "cervix" }
{ "id": "C0266404", "pos": [ 27, 44 ], "name": "cervical agenesis" }
11finding_site_of
Interestingly , the inhibition of Akt pathway at the level of Akt-Pdpk1 interaction was sufficient to suppress the growth of tumor cells and no significant additive effect could be detected when co-treated with the inhibitors of Wnt , Hedgehog or Notch pathways .
{ "id": "C0442726", "pos": [ 181, 189 ], "name": "detected" }
{ "id": "C0037420", "pos": [ 72, 83 ], "name": "interaction" }
0NA
Intranasal immunization with Ad85A inhibits Mtb growth in the early phase of infection , up to day 8 .
{ "id": "C0020971", "pos": [ 11, 23 ], "name": "immunization" }
{ "id": "C0009450", "pos": [ 77, 86 ], "name": "infection" }
0NA
These findings suggest that a single measurement of serum PRL within 24 to 48 following transphenoidal adenomectomy is a reliable indicator of the success or failure of the procedure .
{ "id": "C0184661", "pos": [ 173, 182 ], "name": "procedure" }
{ "id": "C0033371", "pos": [ 58, 61 ], "name": "PRL" }
0NA
The methods of caries removal have been the subject of many studies over the last years .
{ "id": "C0015252", "pos": [ 22, 29 ], "name": "removal" }
{ "id": "C0011334", "pos": [ 15, 21 ], "name": "caries" }
0NA
There was a statistically significant difference in two arms of treatment regarding to surgically induced astigmatism after 3 months .
{ "id": "C0004106", "pos": [ 106, 117 ], "name": "astigmatism" }
{ "id": "C0543467", "pos": [ 87, 97 ], "name": "surgically" }
0NA
Joints were assessed for gross pathology ( cartilage erosion and osteophytes ) , histomorphometry , two histopathology scoring methods ( modified Mankin-type and Pritzker score ) , and immunohistology for ADAMTS- and MMP-cleaved neoepitopes , at 12 weeks post-op .
{ "id": "C0022417", "pos": [ 0, 6 ], "name": "Joints" }
{ "id": "C0007301", "pos": [ 43, 52 ], "name": "cartilage" }
0NA
After both kidneys were injected with a blue modified Gerota mass , lymph vessels were dissected until their termination .
{ "id": "C0022646", "pos": [ 11, 18 ], "name": "kidneys" }
{ "id": "C0229889", "pos": [ 68, 81 ], "name": "lymph vessels" }
0NA
Hyperpolarized ( hp ) (83)Kr ( spin I=9/2 ) is a promising gas-phase contrast agent that displays sensitivity to the surface chemistry , surface-to-volume ratio , and surface temperature of the surrounding environment .
{ "id": "C0020517", "pos": [ 98, 109 ], "name": "sensitivity" }
{ "id": "C0005903", "pos": [ 175, 186 ], "name": "temperature" }
0NA
We tested this hypothesis by inducing doxorubicin nephrosis with 1 , 2 and 3 mg/kg , and evaluating the response to intervention with lisinopril .
{ "id": "C0013089", "pos": [ 38, 49 ], "name": "doxorubicin" }
{ "id": "C0065374", "pos": [ 134, 144 ], "name": "lisinopril" }
0NA
A 33-year-old man with a history of toxoplasmosis chorioretinitis reported 1 week of decreased vision to 20/200 in his right eye .
{ "id": "C0229089", "pos": [ 119, 128 ], "name": "right eye" }
{ "id": "C0042789", "pos": [ 95, 101 ], "name": "vision" }
0NA
At certain " critical " points along their course , local aggression of the vessels may cause lymphedema .
{ "id": "C0005847", "pos": [ 76, 83 ], "name": "vessels" }
{ "id": "C0024236", "pos": [ 94, 104 ], "name": "lymphedema" }
0NA
Taking the autopsy data into account , the cumulative incidence of the two tumours was 16.8 % for KS and 16.5 % for NHL .
{ "id": "C0027651", "pos": [ 75, 82 ], "name": "tumours" }
{ "id": "C0024305", "pos": [ 116, 119 ], "name": "NHL" }
0NA
Similarly , diabetic nephropathy is increasingly considered an inflammatory disease , with immune modulation being involved in both the development and progression of the disease .
{ "id": "C1290884", "pos": [ 63, 83 ], "name": "inflammatory disease" }
{ "id": "C0012634", "pos": [ 171, 178 ], "name": "disease" }
0NA
More studies are warranted to allow the construction of a model for the interaction between host immunity , aging , and the environment .
{ "id": "C0441513", "pos": [ 40, 52 ], "name": "construction" }
{ "id": "C0037420", "pos": [ 72, 83 ], "name": "interaction" }
0NA
Other sulfate ester derivatives of testosterone , estrone , pregnenolone and dehydroepiandrosterone and cholesterol tested did not show any effect on the activation of Factor XII and prekallikrein .
{ "id": "C0011185", "pos": [ 77, 99 ], "name": "dehydroepiandrosterone" }
{ "id": "C0039601", "pos": [ 35, 47 ], "name": "testosterone" }
0NA
High levels of heavy metals ( Hg , Pb , Cd and As ) found in the liver and kidneys might have contributed to the animal 's demise .
{ "id": "C0022646", "pos": [ 75, 82 ], "name": "kidneys" }
{ "id": "C0023884", "pos": [ 65, 70 ], "name": "liver" }
0NA
These normal data should be useful in assessing patients with congenital heart disease , particularly those in whom pulmonary blood flow is abnormal .
{ "id": "C0205161", "pos": [ 140, 148 ], "name": "abnormal" }
{ "id": "C0152021", "pos": [ 62, 86 ], "name": "congenital heart disease" }
0NA
The mean levels of serum ammonia in the group of cirrhotic patients with H. pylori infection were 167.82 + /- 8.97 mumol/L ( portal vein ) and 142.2 + /- 13.35 mumol/L ( cubital vein ) .
{ "id": "C0002607", "pos": [ 25, 32 ], "name": "ammonia" }
{ "id": "C0850666", "pos": [ 73, 92 ], "name": "H. pylori infection" }
0NA
Repeat testing more than one week apart does not appear to influence the glucose , ACTH or cortisol response to insulin stress .
{ "id": "C0017725", "pos": [ 73, 80 ], "name": "glucose" }
{ "id": "C0001655", "pos": [ 83, 87 ], "name": "ACTH" }
0NA
Physician counselling and pharmacotherapy for smoking cessation do not appear to be received more frequently among individuals with COPD or asthma compared to the general smoking population , despite the greater vulnerability of such patients to smoking effects .
{ "id": "C0010210", "pos": [ 10, 21 ], "name": "counselling" }
{ "id": "C0004096", "pos": [ 140, 146 ], "name": "asthma" }
0NA
In all patients there was either no , or abnormally low , transit at the level of the left colon and rectum .
{ "id": "C0034896", "pos": [ 101, 107 ], "name": "rectum" }
{ "id": "C0227388", "pos": [ 86, 96 ], "name": "left colon" }
0NA
Individuals with cervical spinal cord lesions are characterised by markedly decreased aerobic capacity , accompanied by increased risk of developing cardiovascular disease .
{ "id": "C0221198", "pos": [ 38, 45 ], "name": "lesions" }
{ "id": "C0007222", "pos": [ 149, 171 ], "name": "cardiovascular disease" }
0NA
Our results suggest that ACP acts by interacting with the SK channel , to block the facilitatory effect of low concentration of ethanol , on network activity in hippocampal cultures .
{ "id": "C0028778", "pos": [ 74, 79 ], "name": "block" }
{ "id": "C0019564", "pos": [ 161, 172 ], "name": "hippocampal" }
0NA
Our findings provide additional evidence of abnormalities in the genu of the corpus callosum in early onset depression that persist into adulthood .
{ "id": "C0000768", "pos": [ 44, 57 ], "name": "abnormalities" }
{ "id": "C0010090", "pos": [ 77, 92 ], "name": "corpus callosum" }
0NA
Ticks , blood-sucking arthropods , serve as vectors for transmission of infectious diseases including Lyme borreliosis .
{ "id": "C0009450", "pos": [ 72, 91 ], "name": "infectious diseases" }
{ "id": "C0024198", "pos": [ 102, 118 ], "name": "Lyme borreliosis" }
0NA
A portable neodymium : yttrium aluminium garnet ( Nd : YAG ) laser was used to perform capsulotomies on all eyes with visually significant PCO .
{ "id": "C0015392", "pos": [ 108, 112 ], "name": "eyes" }
{ "id": "C0032460", "pos": [ 139, 142 ], "name": "PCO" }
0NA
GI toxicity rates were 9.3 per 1000 person-years after three-dimensional conformal radiotherapy , 8.9 per 1000 person-years after intensity-modulated radiotherapy , 5.3 per 1000 person-years after brachytherapy alone , 20.1 per 1000 person-years after proton therapy , and 2.1 per 1000 person-years for conservative management patients .
{ "id": "C0006098", "pos": [ 197, 210 ], "name": "brachytherapy" }
{ "id": "C1512814", "pos": [ 130, 162 ], "name": "intensity-modulated radiotherapy" }
0NA
Treatment with 5 mg prednisone at bedtime , and 0.625 to 1.25 mg conjugated estrogens daily except during menses resulted in a signficant decrease in serum 17 beta-ol androgens , and an even more statistically significant increase in serum androgen binding .
{ "id": "C0014939", "pos": [ 76, 85 ], "name": "estrogens" }
{ "id": "C0032952", "pos": [ 20, 30 ], "name": "prednisone" }
0NA
Accordingly , there is considerable current interest in their use as antimicrobial agents against different pathogens like bacteria , virus , fungi or parasites , multidrug-resistant strains and biofilms ; as targeting vectors towards specific tissues ; as vaccines and as theranostic systems .
{ "id": "C0042210", "pos": [ 257, 265 ], "name": "vaccines" }
{ "id": "C1136254", "pos": [ 69, 89 ], "name": "antimicrobial agents" }
0NA
Reports an error in " On the Association Between Loneliness and Physical Warmth-Seeking Through Bathing : Reply to Donnellan et al. ( 2014 ) and Three Further Replications of Bargh and Shalev ( 2012 ) Study 1 " by Idit Shalev and John Bargh ( Emotion , Advanced Online Publication , Sep 8 , 2014 , np ) .
{ "id": "C0023974", "pos": [ 49, 59 ], "name": "Loneliness" }
{ "id": "C0013987", "pos": [ 243, 250 ], "name": "Emotion" }
15interprets
The efficacy of phenoxybenzamine and carbachol for the prevention of prolonged micturition problems was investigated in 160 consecutive patients with postoperative urinary retention .
{ "id": "C0199176", "pos": [ 55, 65 ], "name": "prevention" }
{ "id": "C0080274", "pos": [ 164, 181 ], "name": "urinary retention" }
0NA
Clinical evaluation and follow-up were continued and CXR was performed sequentially in two-day intervals until clinical improvement or occurrence of other events including death .
{ "id": "C0011065", "pos": [ 172, 177 ], "name": "death" }
{ "id": "C1261322", "pos": [ 0, 19 ], "name": "Clinical evaluation" }
0NA
Male Wistar rats received subcutaneous injections of saline , oleic acid ( OA ) , or DHA .
{ "id": "C0556150", "pos": [ 85, 88 ], "name": "DHA" }
{ "id": "C0086582", "pos": [ 0, 4 ], "name": "Male" }
0NA
While the Clinical and Laboratory Standards Institute ( CLSI ) recommends against routine screening for extended spectrum β-lactamases ( ESBLs ) , knowledge of these data can provide valuable insights regarding epidemiology and drug therapy decisions .
{ "id": "C0013216", "pos": [ 228, 240 ], "name": "drug therapy" }
{ "id": "C0199230", "pos": [ 90, 99 ], "name": "screening" }
0NA
Twenty adult patients underwent tonsillectomy , each having one randomly selected tonsil removed by dissection and the other removed by coblation .
{ "id": "C0040421", "pos": [ 82, 88 ], "name": "tonsil" }
{ "id": "C0040423", "pos": [ 32, 45 ], "name": "tonsillectomy" }
9direct_procedure_site_of
Central nervous system endothelial cells were isolated from human brain and retina and cultured in vitro in a transwell system .
{ "id": "C0006104", "pos": [ 66, 71 ], "name": "brain" }
{ "id": "C0035298", "pos": [ 76, 82 ], "name": "retina" }
0NA
Tinnitus assessment , neuroimaging , and cognitive testing were completed at baseline and 8 weeks later .
{ "id": "C0031809", "pos": [ 9, 19 ], "name": "assessment" }
{ "id": "C0040264", "pos": [ 0, 8 ], "name": "Tinnitus" }
0NA
The disposition parameters of MMC-Dcat with a molecular weight of 500,000 ( T-500 ) indicated some tissue distribution and sequestration in the tumor preparation .
{ "id": "C0027651", "pos": [ 144, 149 ], "name": "tumor" }
{ "id": "C0040300", "pos": [ 99, 105 ], "name": "tissue" }
0NA
In conclusion , we present emerging concepts about the functional plasticity of secretory pathways and their modulation for controlling cytokines and inflammation .
{ "id": "C0021368", "pos": [ 150, 162 ], "name": "inflammation" }
{ "id": "C0079189", "pos": [ 136, 145 ], "name": "cytokines" }
0NA
From a physiological point of view , basal GC levels are essential for intermediary metabolism and participate in the development and homeostasis of a wide range of body tissues , including the skeleton .
{ "id": "C0037253", "pos": [ 194, 202 ], "name": "skeleton" }
{ "id": "C0040300", "pos": [ 165, 177 ], "name": "body tissues" }
0NA
After raising the abdominal wall , the scope is introduced through the same access and the laparoscopic procedure can be started without the technical and pathophysiological problems which may occur when using a pneumoperitoneum .
{ "id": "C0836916", "pos": [ 18, 32 ], "name": "abdominal wall" }
{ "id": "C0032320", "pos": [ 212, 228 ], "name": "pneumoperitoneum" }
0NA
Osteochondral lesions of the wrist are rare in the pediatric and adolescent population .
{ "id": "C0221198", "pos": [ 14, 21 ], "name": "lesions" }
{ "id": "C0043262", "pos": [ 29, 34 ], "name": "wrist" }
0NA
In the neonatal cat and guinea pig portal veins the pattern of the spontaneous activity and induced responses resembled those found in vessels from adult animals .
{ "id": "C0005847", "pos": [ 135, 142 ], "name": "vessels" }
{ "id": "C0032718", "pos": [ 35, 47 ], "name": "portal veins" }
0NA
Unlike gabapentin , intrathecal clonidine and neostigmine attenuate both acute pain and phase 2 of the formalin response .
{ "id": "C0027679", "pos": [ 46, 57 ], "name": "neostigmine" }
{ "id": "C0060926", "pos": [ 7, 17 ], "name": "gabapentin" }
0NA
Long-term preservation of corneas by freezing has long been a major goal in eye banking because indefinite storage by cryopreservation offers significant advantages for the quality and the quantity of material for use in keratoplasty , as well as for its distribution .
{ "id": "C0010031", "pos": [ 26, 33 ], "name": "corneas" }
{ "id": "C0010042", "pos": [ 221, 233 ], "name": "keratoplasty" }
9direct_procedure_site_of
More precise risk assessments for prostate cancer detection are needed for men faced with an abnormal PSA .
{ "id": "C0205161", "pos": [ 93, 101 ], "name": "abnormal" }
{ "id": "C0376358", "pos": [ 34, 49 ], "name": "prostate cancer" }
0NA
Blood flow resistance in the dominant ovarian artery was lower in ISDN-treated pregnant mares than in placebo-treated pregnant and cycling mares ( treatment effect : P   =   0.04 ; time effect : P   =   0.003 ) .
{ "id": "C0549206", "pos": [ 118, 126 ], "name": "pregnant" }
{ "id": "C0226411", "pos": [ 38, 52 ], "name": "ovarian artery" }
0NA
Sonohysterography provides a diagnostic accuracy as well as hysteroscopy , therefore , it could be considered an alternative procedure in the diagnosis of benign uterine endocavitary findings .
{ "id": "C0042149", "pos": [ 162, 169 ], "name": "uterine" }
{ "id": "C0020710", "pos": [ 60, 72 ], "name": "hysteroscopy" }
9direct_procedure_site_of
Failure to make the diagnosis of persistent sciatic artery and popliteal entrapment can result in critical limb ischemia and subsequent amputation .
{ "id": "C0002688", "pos": [ 136, 146 ], "name": "amputation" }
{ "id": "C0022116", "pos": [ 112, 120 ], "name": "ischemia" }
0NA
There appear correlations between resistance to hypoxia and red cell count , hemoglobin and hematocrit .
{ "id": "C0019046", "pos": [ 77, 87 ], "name": "hemoglobin" }
{ "id": "C0014772", "pos": [ 60, 74 ], "name": "red cell count" }
0NA
Incubation of erythrocyte membranes instead of intact erythrocytes with glucose and glucose-6-phosphate strongly suggests that only the glycosylation of the membrane inner-surface proteins can affect Ca2(+)-ATPase activity .
{ "id": "C0017725", "pos": [ 72, 79 ], "name": "glucose" }
{ "id": "C0014772", "pos": [ 54, 66 ], "name": "erythrocytes" }
0NA
In an attempt to save it anyway , after debridement , sandblasting and decontamination of both implant surfaces an enzyme-deantigenic collagenic bone substitute was grafted .
{ "id": "C0011079", "pos": [ 40, 51 ], "name": "debridement" }
{ "id": "C0021102", "pos": [ 95, 102 ], "name": "implant" }
0NA
Conclusion Elective B-Lynch suture is cheap , quick and effective in preventing atonic Postpartum Haemorrhage in women undergoing emergency lower segment caesarian section who are at high risk for haemorrhage .
{ "id": "C0019080", "pos": [ 197, 208 ], "name": "haemorrhage" }
{ "id": "C0032797", "pos": [ 87, 109 ], "name": "Postpartum Haemorrhage" }
3associated_morphology_of
Thus , the altered protein metabolism in moderately hyperglycemic NIDDM subjects was improved with exogenous insulin in doses sufficient to restore normoglycemia in the isoenergetic fed state , but it remained abnormal with a reduced non-protein energy intake .
{ "id": "C0205161", "pos": [ 210, 218 ], "name": "abnormal" }
{ "id": "C0021641", "pos": [ 109, 116 ], "name": "insulin" }
0NA
In blood , the binding of CPT-11 was moderate ( 80 % ) , mainly to plasma proteins ( 47 % ) and erythrocytes ( 33 % ) .
{ "id": "C0005767", "pos": [ 3, 8 ], "name": "blood" }
{ "id": "C0014772", "pos": [ 96, 108 ], "name": "erythrocytes" }
0NA
Major points emerging are the limitations of post-traumatic amnesia as an index of the severity of a minor head injury , and the high incidence of symptoms on return to work and later , in patients who were at work and without compensation claims .
{ "id": "C0425105", "pos": [ 159, 173 ], "name": "return to work" }
{ "id": "C0018674", "pos": [ 107, 118 ], "name": "head injury" }
0NA
A 74 year-old man with a past medical history of idiopathic thrombocytopenic purpura , splenectomy , autoimmune hemolytic anemia , and polymyalgia rheumatica developed HZ on the right median nerve 7 days after he underwent a coronariography for managing an acute coronary syndrome .
{ "id": "C0002880", "pos": [ 101, 128 ], "name": "autoimmune hemolytic anemia" }
{ "id": "C0948089", "pos": [ 257, 280 ], "name": "acute coronary syndrome" }
0NA
Genetic analysis revealed a homozygous mutation , p. W60X , in exon 3 of the IL12B gene , resulting in complete IL12p40 deficiency .
{ "id": "C0019904", "pos": [ 28, 38 ], "name": "homozygous" }
{ "id": "C0679560", "pos": [ 0, 16 ], "name": "Genetic analysis" }
15interprets
This occurs especially at the point of indication ( maximum diameter ) and the total length of the aneurysm ( important for correct stent graft selection ) .
{ "id": "C0002940", "pos": [ 99, 107 ], "name": "aneurysm" }
{ "id": "C0038257", "pos": [ 132, 137 ], "name": "stent" }
0NA
A headspace vial containing the urine sample , NaOH , NaCl , and amphetamine-d3 as the internal standard was heated at 100 degrees C for 20 min .
{ "id": "C1610733", "pos": [ 32, 44 ], "name": "urine sample" }
{ "id": "C0037494", "pos": [ 54, 58 ], "name": "NaCl" }
0NA
LEPs to stimulation of the affected side were abnormal because of absent , reduced or delayed responses .
{ "id": "C0205161", "pos": [ 46, 54 ], "name": "abnormal" }
{ "id": "C1292856", "pos": [ 8, 19 ], "name": "stimulation" }
0NA
The aim of the study was to evaluate mechanical behavior of implants inserted in three substrates , by measuring the pullout strength and the relative stiffness .
{ "id": "C0441587", "pos": [ 69, 77 ], "name": "inserted" }
{ "id": "C0021102", "pos": [ 60, 68 ], "name": "implants" }
0NA
Inhibition of prostaglandin synthesis mediates closure of the ductus arteriosus and renal side effects after indomethacin administration .
{ "id": "C0185003", "pos": [ 47, 54 ], "name": "closure" }
{ "id": "C0021246", "pos": [ 109, 121 ], "name": "indomethacin" }
0NA
The patient underwent removal of the labia majora , and was reconstructed with a bi-lobed abdominal flap tunneled through the mons pubis .
{ "id": "C0015252", "pos": [ 22, 29 ], "name": "removal" }
{ "id": "C0227760", "pos": [ 37, 49 ], "name": "labia majora" }
0NA
Randomized controlled trials addressing self-management support interventions for patients with cardiovascular disease , stroke , cancer , diabetes and/or chronic respiratory disease were included .
{ "id": "C0038454", "pos": [ 121, 127 ], "name": "stroke" }
{ "id": "C0264220", "pos": [ 155, 182 ], "name": "chronic respiratory disease" }
0NA
Perioperative management should include careful evaluation of the airway as the extent of compression and deviation caused by the mass can lead to a difficult intubation .
{ "id": "C0577559", "pos": [ 130, 134 ], "name": "mass" }
{ "id": "C0021925", "pos": [ 159, 169 ], "name": "intubation" }
0NA
CRF was found to inhibit dose-dependently gastric acid response to pentagastrin but not to histamine .
{ "id": "C0019588", "pos": [ 91, 100 ], "name": "histamine" }
{ "id": "C0030859", "pos": [ 67, 79 ], "name": "pentagastrin" }
0NA
Independent risk factors associated with RSVH include : proximity of birth to the RSV season , living with school-age siblings , smoking of mother during pregnancy or infant exposure to environmental smoking , reduced breast feeding , male sex , and familial atopy ( asthma ) ( high SOE ) .
{ "id": "C0004096", "pos": [ 267, 273 ], "name": "asthma" }
{ "id": "C0086582", "pos": [ 235, 239 ], "name": "male" }
0NA
Beginning with a clinical case report we proceed to present a general overview of the clinical features and pathophysiology of diabetes mellitus , followed by a critical discussion of the results of a systematic literature search for aspects of the disease relevant to orthodontics .
{ "id": "C0011849", "pos": [ 127, 144 ], "name": "diabetes mellitus" }
{ "id": "C0012634", "pos": [ 249, 256 ], "name": "disease" }
0NA
We used a regression model incorporating all three joint or limb segment angles and performed a backward elimination of insignificant or redundant variables .
{ "id": "C0022417", "pos": [ 51, 56 ], "name": "joint" }
{ "id": "C0425087", "pos": [ 137, 146 ], "name": "redundant" }
0NA
1,683 participants ( 1,683 eyes ) from the Handan Eye Study were involved , including 955 female and 728 male with average age of 53.64 years old ( range from 30 to 107 years ) .
{ "id": "C0015392", "pos": [ 27, 31 ], "name": "eyes" }
{ "id": "C0086582", "pos": [ 105, 109 ], "name": "male" }
0NA
The successful use of the Endo-Coagulator , an electronically regulated apparatus for pelviscopy and coagulation of tubes , adhesions or , bleeding areas after ovarian biopsy is reported .
{ "id": "C0001511", "pos": [ 124, 133 ], "name": "adhesions" }
{ "id": "C0195484", "pos": [ 160, 174 ], "name": "ovarian biopsy" }
0NA
Generally , the flap matched the surrounding skin .
{ "id": "C0444099", "pos": [ 45, 49 ], "name": "skin" }
{ "id": "C0038925", "pos": [ 16, 20 ], "name": "flap" }
0NA
The technique is simple and most suitable for the correction of crossbite and Class III malocclusion and for establishing a nasal airway in habitual mouth breathers with a history of ENT problems .
{ "id": "C0226896", "pos": [ 149, 154 ], "name": "mouth" }
{ "id": "C0399526", "pos": [ 78, 100 ], "name": "Class III malocclusion" }
0NA
Based on elastase and hyaluronidase inhibitions , and type II collagen expression , it could be suggested that PGG might have an influence on skin conditions when used cosmetically as an active anti-aging ingredient with no cytotoxicity ; also , it might be beneficial in relieving painful joint conditions , and thus have relevance for treating arthritis .
{ "id": "C0030193", "pos": [ 282, 289 ], "name": "painful" }
{ "id": "C0037274", "pos": [ 142, 157 ], "name": "skin conditions" }
0NA
Pathogenesis of pruritus of cholestasis remains poorly understood .
{ "id": "C0008370", "pos": [ 28, 39 ], "name": "cholestasis" }
{ "id": "C0033774", "pos": [ 16, 24 ], "name": "pruritus" }
0NA
Treatment of 10 % FBRA significantly reduced the mRNA expression levels of cytochrome P450 2A5 ( Cyp2a5 ) , which is known to be closely related to the human CYP2A6 enzyme that is involved in the mutagenic activation of NNK , in the lung but not liver tissues .
{ "id": "C0024109", "pos": [ 233, 237 ], "name": "lung" }
{ "id": "C0736268", "pos": [ 246, 259 ], "name": "liver tissues" }
0NA
Eighty one patients harboring 104 aneurysms were diagnosed , of them 45 were males ( 55.5 % ) and 36 were females ( 44.5 % ) .
{ "id": "C0002940", "pos": [ 34, 43 ], "name": "aneurysms" }
{ "id": "C0086287", "pos": [ 106, 113 ], "name": "females" }
0NA
Cobalt oxide nanoparticles ( Co(3)O(4)NPs ) are increasingly recognized for their utility in biological applications , magnetic resonance imaging , and drug delivery .
{ "id": "C0024485", "pos": [ 119, 145 ], "name": "magnetic resonance imaging" }
{ "id": "C0185125", "pos": [ 104, 116 ], "name": "applications" }
0NA
We have devised a new position ( Monzen position ) which can suppress the influence of scattered rays from surrounding organs ( liver , etc . ) when conducting myocardial imaging .
{ "id": "C0023884", "pos": [ 128, 133 ], "name": "liver" }
{ "id": "C0203713", "pos": [ 160, 178 ], "name": "myocardial imaging" }
0NA
We observed the specific attachment of the functionalized gold plasmonic nanoparticles ( AuNPs ) targeting CD44(+ ) human breast cancer cells by conventional and by proposed hyperspectral darkfield microscopy .
{ "id": "C0185023", "pos": [ 25, 35 ], "name": "attachment" }
{ "id": "C0018026", "pos": [ 58, 62 ], "name": "gold" }
0NA
Twelve patients with drug overdoses involving 20 different ( a total of 32 ) drugs were hemoperfused using a charcoal column at Japanese Red Cross Kumamoto Hospital in 2000 .
{ "id": "C0013227", "pos": [ 77, 82 ], "name": "drugs" }
{ "id": "C0029944", "pos": [ 21, 35 ], "name": "drug overdoses" }
4causative_agent_of