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To clarify the roles of perforin in Ag-specific cytotoxicity mediated by human CD4+ CTLs, alloantigen-specific and HSV-specific human CD4+ T lymphocyte bulk lines and clones were established from a patient with hereditary perforin deficiency and her healthy father, and their cytotoxic activities were investigated. | NA | {
"id": 920,
"name": "CD4",
"pos": [
79,
3
]
} | {
"id": "C4288409",
"name": "Perforin Deficiency",
"pos": [
222,
19
]
} |
We provide evidence that sorafenib has a selective action on glioblastoma stem cells, causing enrichment of cultures in differentiated cells, downregulation of the expression of stemness markers required to maintain malignancy (nestin, Olig2 and Sox2) and reducing cell clonogenic ability in vitro and tumorigenic potential in vivo. | biomarker | {
"id": 10763,
"name": "NES",
"pos": [
228,
6
]
} | {
"id": "C0006826",
"name": "Malignant Neoplasms",
"pos": [
216,
10
]
} |
TLG determined per RECIST 1.1 criteria is an independent predictor of OS in EGFR mutation-negative patients with advanced lung adenocarcinoma. | genomic_alterations | {
"id": 1956,
"name": "EGFR",
"pos": [
76,
4
]
} | {
"id": "C0152013",
"name": "Adenocarcinoma of lung (disorder)",
"pos": [
122,
19
]
} |
Functional investigations of the VHL gene product have provided novel information on how cells sense oxygen and the role of hypoxia-response pathways in human tumourigenesis. | NA | {
"id": 7428,
"name": "VHL",
"pos": [
33,
8
]
} | {
"id": "C0242184",
"name": "Hypoxia",
"pos": [
124,
7
]
} |
A total of 30 prostate tumor specimens were investigated for promoter methylation status of TS hypermethylated in cancer 1 (HIC1), death-associated protein kinase 1 (DAPK1), secreted frizzled-related protein 2 (SFRP2), cyclin-dependent kinase inhibitor 2A (p16), and O-6-methylguanine-DNA methyltransferase (MGMT) genes by using bisulfite modifying method. | NA | {
"id": 2487,
"name": "FRZB",
"pos": [
183,
24
]
} | {
"id": "C0033578",
"name": "Prostatic Neoplasms",
"pos": [
14,
14
]
} |
Amyotrophic lateral sclerosis (ALS) is caused by mutations in the gene for Cu/Zn superoxide dismutase (SOD1) in 10% of familial and sporadic cases. | NA | {
"id": 6647,
"name": "SOD1",
"pos": [
103,
4
]
} | {
"id": "C1853237",
"name": "Isolated cases",
"pos": [
132,
8
]
} |
Collectively, our findings suggested miR-1303 promotes NB proliferation by targeting GSK3β and SFRP1, and might be a target for NB therapy. | biomarker | {
"id": 100302284,
"name": "MIR1303",
"pos": [
37,
8
]
} | {
"id": "C4086165",
"name": "Childhood Neuroblastoma",
"pos": [
55,
2
]
} |
We showed that XPC A499V was associated with increased risk of HNSCC, especially laryngeal carcinoma. | genomic_alterations | {
"id": 7508,
"name": "XPC",
"pos": [
15,
3
]
} | {
"id": "C0595989",
"name": "Carcinoma of larynx",
"pos": [
81,
19
]
} |
Patients with monocytes that expressed the greatest amount of TNF-alpha demonstrated higher prevalence of choroidal neovascularization. | NA | {
"id": 7124,
"name": "TNF",
"pos": [
62,
9
]
} | {
"id": "C0600518",
"name": "Choroidal Neovascularization",
"pos": [
106,
28
]
} |
Our results confirm the relatively low incidence of p53 mutations in AML and further support the evidence that p53 plays a role in leukemogenesis through a recessive mechanism (two-hit model) of inactivation of tumor suppressor activity. | NA | {
"id": 7157,
"name": "TP53",
"pos": [
111,
3
]
} | {
"id": "C0272285",
"name": "Heparin-induced thrombocytopenia",
"pos": [
181,
3
]
} |
Treatment of fibroblasts with TGF-β1, oxidative stress, UV light, and hypoxia induced a significant increase in expression levels of LOXL1 and elastic proteins, whereas the effect of IL-6 was limited to induction of elastic constituents. | NA | {
"id": 4016,
"name": "LOXL1",
"pos": [
133,
5
]
} | {
"id": "C0242184",
"name": "Hypoxia",
"pos": [
70,
7
]
} |
Treatment with TGF-beta or expression of an activated TGF-beta type I receptor (Alk5 with the mutation T204D [Alk5(T204D)]) induced phosphorylation of TACE/ADAM17 and its translocation to the cell surface, resulting in increased secretion of TGF-alpha, amphiregulin, and heregulin. | NA | {
"id": 6868,
"name": "ADAM17",
"pos": [
156,
6
]
} | {
"id": "C0040715",
"name": "Chromosomal translocation",
"pos": [
171,
13
]
} |
These studies suggest that a t(9;14)(p21;q32) chromosomal translocation can result in deletion of both p16 INK4A and p15 INK4B genes in pre-B ALL, and that the JKB2 cell line therefore provides a model for the study of leukemogenesis related to abnormalities in chromosome 9p2l. | NA | {
"id": 1026,
"name": "CDKN1A",
"pos": [
37,
3
]
} | {
"id": "C0000768",
"name": "Congenital Abnormality",
"pos": [
245,
13
]
} |
The effect of alcohol consumption on the risk of breast cancer varied according to the allelic variants of the rs2981582 polymorphism in the FGFR2 gene: OR = 3.97 (95% CI 2.10-7.49), OR = 2.01 (95% CI 1.23-3.29) and OR = 1.21 (95% CI 0.48-3.05) for genotypes CC, CT and TT, respectively. | NA | {
"id": 2263,
"name": "FGFR2",
"pos": [
141,
10
]
} | {
"id": "C0001948",
"name": "Alcohol consumption",
"pos": [
14,
19
]
} |
In three Centre d'Etude du Polymorphisme Humain families, meiotic breakpoint analysis using these two polymorphic loci localized the CC10 gene to 11 p12-q13 between markers D11S16 and D11S97, a region recently linked to atopy and to the beta-subunit of the high-affinity immunoglobulin E receptor. | NA | {
"id": 7356,
"name": "SCGB1A1",
"pos": [
133,
4
]
} | {
"id": "C0392707",
"name": "Atopy",
"pos": [
220,
5
]
} |
Advanced glycation endproducts (AGEs) produced as the result of hyperglycemia are known to stimulate the production of extracellular matrix (ECM) proteins, resulting in glomerulosclerosis. | biomarker | {
"id": 22915,
"name": "MMRN1",
"pos": [
141,
3
]
} | {
"id": "C0020456",
"name": "Hyperglycemia",
"pos": [
64,
13
]
} |
The ADRB3 W64R polymorphism was significantly associated with body weight and BMI in men but not in women. | NA | {
"id": 155,
"name": "ADRB3",
"pos": [
4,
5
]
} | {
"id": "C0005910",
"name": "Body Weight",
"pos": [
62,
11
]
} |
Therefore, these results indicate that a rapid translocation of CD45RO to lipid rafts may be responsible for IL-6-induced proliferation, and that the change from CD45RA to CD45RO confers the ability to respond to IL-6 in human myeloma cells. | NA | {
"id": 3569,
"name": "IL6",
"pos": [
109,
4
]
} | {
"id": "C0040715",
"name": "Chromosomal translocation",
"pos": [
47,
13
]
} |
Significance of 5,10-methylenetetrahydrofolate reductase gene variants in acute lymphoblastic leukemia in Indian population: an experimental, computational and meta-analysis. | genomic_alterations | {
"id": 4524,
"name": "MTHFR",
"pos": [
21,
35
]
} | {
"id": "C1961102",
"name": "Precursor Cell Lymphoblastic Leukemia Lymphoma",
"pos": [
74,
28
]
} |
Overexpression p21WAF1/CIP1 in suppressing retinal pigment epithelial cells and progression of proliferative vitreoretinopathy via inhibition CDK2 and cyclin E. | biomarker | {
"id": 56996,
"name": "SLC12A9",
"pos": [
23,
4
]
} | {
"id": "C0242852",
"name": "Proliferative vitreoretinopathy",
"pos": [
95,
31
]
} |
In this study, we analyzed the association genetic polymorphisms of N-acetyltransferase 1 (NAT1) with genetic susceptibility to sporadic colorectal adenocarcinoma (SCRAC). | NA | {
"id": 9,
"name": "NAT1",
"pos": [
91,
4
]
} | {
"id": "C1853237",
"name": "Isolated cases",
"pos": [
128,
8
]
} |
We found Ewing's sarcoma cell lines, overall, were more sensitive to the PARP inhibitor olaparib than osteosarcoma cell lines; however, while the effect was in the same direction as the original study (Figure 4C; Garnett et al., 2012), it was not statistically significant. | biomarker | {
"id": 142,
"name": "PARP1",
"pos": [
73,
4
]
} | {
"id": "C0029463",
"name": "Osteosarcoma",
"pos": [
102,
12
]
} |
To date, there are no such studies regarding fibrolamellar carcinoma, a less common variant of HCC, which usually affects young people and displays distinct morphological features. | NA | {
"id": 84668,
"name": "FAM126A",
"pos": [
95,
3
]
} | {
"id": "C0334287",
"name": "Fibrolamellar Hepatocellular Carcinoma",
"pos": [
45,
23
]
} |
Patients with alpha-thalassemia had a lower MCHC than patients with four alpha-globin genes and this was not significantly affected by the level of Hb F. The combination of alpha-thalassemia and high levels of Hb F appears to result in a distinctive S/S phenotype that is similar to the type of S/S disease described in Southern India. | genomic_alterations | {
"id": 3039,
"name": "HBA1",
"pos": [
73,
12
]
} | {
"id": "C1456873",
"name": "alpha^+^ Thalassemia",
"pos": [
173,
17
]
} |
The t(14;19)(q32;q13) is a recurring translocation found in some patients with chronic lymphocytic leukemia (CLL), and the t(14;19) juxtaposes the BCL3 gene on chromosome 19 with the immunoglobulin heavy chain gene (IGH) locus on chromosome 14. | NA | {
"id": 3492,
"name": "IGH",
"pos": [
216,
3
]
} | {
"id": "C0040715",
"name": "Chromosomal translocation",
"pos": [
37,
13
]
} |
In conclusion, nuclear OCT4A may serve as a marker of CCSCs and the driving force for cervical cancer metastasis and recurrence, while cytoplasmic OCT4B may cooperate with OCT4A to regulate the progression of cervical cancer through inducing angiogenesis and EMT. | NA | {
"id": 3702,
"name": "ITK",
"pos": [
259,
3
]
} | {
"id": "C4048328",
"name": "cervical cancer",
"pos": [
209,
15
]
} |
To understand the importance of frequent deletions at chromosome 11q24.1-24.2 region in breast carcinoma, alterations (deletion/methylation) of the candidate genes LOH11CR2A, ROBO3, ROBO4, HEPACAM, PIG8 and CHEK1 located in this region were analyzed in 106 breast carcinoma samples. | NA | {
"id": 54538,
"name": "ROBO4",
"pos": [
182,
5
]
} | {
"id": "C0678222",
"name": "Breast Carcinoma",
"pos": [
257,
16
]
} |
Furthermore, by a discovery-based global approach, comparing cDNA microarray expression profiles of two germ cell tumour cell lines before and after treatment with the demethylating agent 5-aza-2'-deoxycytidine, a gene list of potentially epigenetic targets was identified, from which CGGBP1, CGRRF1, SMARCC2, SORBS1, and XPA were analysed further. | NA | {
"id": 6601,
"name": "SMARCC2",
"pos": [
301,
7
]
} | {
"id": "C0205851",
"name": "Germ cell tumor",
"pos": [
104,
16
]
} |
Erythropoietin (EPO) has been shown to have a cytoprotective effect against hypoxia. | NA | {
"id": 2056,
"name": "EPO",
"pos": [
16,
3
]
} | {
"id": "C0242184",
"name": "Hypoxia",
"pos": [
76,
7
]
} |
The results indicated that BRCA1 and TOC are independent targets of allelic loss on 17q in primary breast cancers, and that inactivation of the TOC locus in particular may play an important role in the genesis of sporadic breast tumors. | NA | {
"id": 672,
"name": "BRCA1",
"pos": [
27,
5
]
} | {
"id": "C1853237",
"name": "Isolated cases",
"pos": [
213,
8
]
} |
With a goal to develop gene therapy for the XLRP-RP2 disease, we first performed detailed characterization of the Rp2-knockout (Rp2-KO) mice and observed early-onset cone dysfunction, which was followed by progressive cone degeneration, mimicking cone vision impairment in XLRP patients. | NA | {
"id": 390916,
"name": "NUDT19",
"pos": [
128,
3
]
} | {
"id": "C3665342",
"name": "Progressive Cone Dystrophy",
"pos": [
206,
29
]
} |
Gastric cancer is one of the most common cancers affecting East Asians, and MLH1 could play a critical role during tumorigenesis in this condition. | NA | {
"id": 4292,
"name": "MLH1",
"pos": [
76,
4
]
} | {
"id": "C0007621",
"name": "Neoplastic Cell Transformation",
"pos": [
115,
13
]
} |
Finally, OCT exerted a preventive as well as therapeutic effect on cancer-associated hypercalcemia with a marked prolongation of the survival time in tumor-bearing animals. | NA | {
"id": 5362,
"name": "PLXNA2",
"pos": [
9,
3
]
} | {
"id": "C0020437",
"name": "Hypercalcemia",
"pos": [
85,
13
]
} |
Potential utility of rhIGF-1 in neuromuscular and/or degenerative disease. | therapeutic | {
"id": 3479,
"name": "IGF1",
"pos": [
23,
5
]
} | {
"id": "C4721453",
"name": "Peripheral Nervous System Diseases",
"pos": [
53,
20
]
} |
Protoporphyrinogen oxidase activity and ferrochelatase activity have been measured in blood lymphocytes from patients with prophyria variegata, and from some members of the family of one patient; the mean activity of protoporphyrinogen oxidase from patients was about 50% of that in lymphocytes from normal subjects; similar results were obtained from asymptomatic carriers in two generations of the patient's family. | NA | {
"id": 5498,
"name": "PPOX",
"pos": [
217,
26
]
} | {
"id": "C0231221",
"name": "Asymptomatic",
"pos": [
352,
12
]
} |
BCL1/PRAD1 is the gene locus involved in the t(11;14)(q13;q32) translocation, which often occurs in a proposed subtype of non-Hodgkin's lymphoma of B-cell phenotype (B-NHL), named mantle cell lymphoma (MCL). | NA | {
"id": 595,
"name": "CCND1",
"pos": [
5,
5
]
} | {
"id": "C0040715",
"name": "Chromosomal translocation",
"pos": [
63,
13
]
} |
Western blot analysis indicated that the Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathway was involved in the mechanisms underlying the in vitro and in vivo inhibitory effects of SIM on cardiac hypertrophy. | NA | {
"id": 6493,
"name": "SIM2",
"pos": [
211,
3
]
} | {
"id": "C1383860",
"name": "Cardiac Hypertrophy",
"pos": [
218,
19
]
} |
CtBP2 is an ovarian cancer oncogene that may play a significant role in epigenetically silencing BRCA1 function in sporadic epithelial ovarian cancer. | NA | {
"id": 672,
"name": "BRCA1",
"pos": [
97,
5
]
} | {
"id": "C1853237",
"name": "Isolated cases",
"pos": [
115,
8
]
} |
hMOF, but not HDAC4, is mainly responsible for global histone H4K16ac acetylation in gastric cancer cells. | NA | {
"id": 84148,
"name": "KAT8",
"pos": [
0,
4
]
} | {
"id": "C0024623",
"name": "Malignant neoplasm of stomach",
"pos": [
85,
14
]
} |
Liver biopsies were performed on 20 chronically HBV-infected (15 HBeAg-positive and 5 HBeAg-negative) patients to assess liver inflammation/fibrosis, and mRNA levels of furin, IL-10, IL-12β, IFN-γ, PD-1, and PD-L1 were assessed by quantitative real-time PCR. | NA | {
"id": 3439,
"name": "IFNA1",
"pos": [
191,
3
]
} | {
"id": "C0016059",
"name": "Fibrosis",
"pos": [
140,
8
]
} |
The association of rare chromosomal rearrangements involving a specific 17q breakpoint with campomelic syndrome (CMPS) and/or sex reversal (SR) has led to an assignment of the CMPS1/SRA1 locus to 17q24.3-->q25.1. | NA | {
"id": 23191,
"name": "CYFIP1",
"pos": [
182,
4
]
} | {
"id": "C4022995",
"name": "Sex reversal",
"pos": [
126,
12
]
} |
Based on the hypothesis that abnormalities of innate immune responses are involved in carcinogenesis, we examined the presence or absence of the expression of Toll-like receptor 4 (TLR4), comprising one of the TLR families, in colorectal cancer tissues. | NA | {
"id": 7099,
"name": "TLR4",
"pos": [
181,
4
]
} | {
"id": "C0000768",
"name": "Congenital Abnormality",
"pos": [
29,
13
]
} |
To undertake analysis of hepatitis A viral load, alanine aminotransferase (ALT), and viral genotypes with duration of viremia, and to correlate these parameters with CD4(+)/ CD8(+) lymphocyte populations that control cell-mediated immunity. | NA | {
"id": 2875,
"name": "GPT",
"pos": [
49,
24
]
} | {
"id": "C0376705",
"name": "Viral Load result",
"pos": [
37,
10
]
} |
Inhibition of MIR21, MIR23A, and MIR27A had synergistic effects in reducing proliferation of PDAC cells in culture and growth of xenograft tumors in mice. | biomarker | {
"id": 407018,
"name": "MIR27A",
"pos": [
33,
6
]
} | {
"id": "C0027651",
"name": "Neoplasms",
"pos": [
139,
6
]
} |
]ryanodine binding sites (Bmax) and the expression levels of ryanodine receptor (RyR) mRNA and calcium-adenosine triphosphatase (Ca2+-ATPase) mRNA in atrial myocardial tissue from 13 patients with AF due to mitral valvular disease (MVD) and 9 patients with normal sinus rhythm (NSR). | NA | {
"id": 4597,
"name": "MVD",
"pos": [
232,
3
]
} | {
"id": "C0026265",
"name": "Diseases of mitral valve",
"pos": [
207,
23
]
} |
However, a trend for total pack-years of smoking was found when p53-positive cases were compared with p53-negative cases suggesting aetiological, heterogeneity (trend test: P = 0.06). | NA | {
"id": 7157,
"name": "TP53",
"pos": [
102,
3
]
} | {
"id": "C0037369",
"name": "Smoking",
"pos": [
41,
7
]
} |
Localized overexpression of FGF-2 and BDNF in hippocampus reduces mossy fiber sprouting and spontaneous seizures up to 4 weeks after pilocarpine-induced status epilepticus. | therapeutic | {
"id": 2247,
"name": "FGF2",
"pos": [
28,
4
]
} | {
"id": "C0022333",
"name": "Jacksonian Seizure",
"pos": [
104,
8
]
} |
Central to the molecular pathogenesis of HCC are mutations of various genes and genetic/chromosomal instability that result from chronic liver disease and the associated enhanced liver cell regeneration and mitotic activity. | NA | {
"id": 84668,
"name": "FAM126A",
"pos": [
41,
3
]
} | {
"id": "C1257806",
"name": "Chromosomal Instability",
"pos": [
88,
23
]
} |
Taking into account the available data, pretreated NSCLC patients carrying the ALK-translocation require a selected targeted therapy which significantly improves activity, efficacy and symptoms control versus chemotherapy. | NA | {
"id": 238,
"name": "ALK",
"pos": [
79,
3
]
} | {
"id": "C0040715",
"name": "Chromosomal translocation",
"pos": [
83,
13
]
} |
Although patients with PDGFRB rearrangement mostly present with myeloproliferative neoplasm and eosinophilia, acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) have also been reported in this population. | genomic_alterations | {
"id": 5159,
"name": "PDGFRB",
"pos": [
23,
6
]
} | {
"id": "C1306759",
"name": "Eosinophilic disorder",
"pos": [
96,
12
]
} |
In present study, functional and mechanism experiments were conducted to investigate the role of long intergenic non-protein coding RNA 00858 (LINC00858) on human osteosarcoma tumorigenesis. | biomarker | {
"id": 170425,
"name": "LINC00858",
"pos": [
143,
9
]
} | {
"id": "C0596263",
"name": "Carcinogenesis",
"pos": [
176,
13
]
} |
Lentiviral-mediated transduction of VE-cadherin and PECAM-1 into REH cells and antibody neutralization of VE-cadherin and PECAM-1 in SUP-B15 cells was used to delineate the role of these two proteins in mediating ALL adhesion to, and migration through, HBMEC monolayers. | NA | {
"id": 9709,
"name": "HERPUD1",
"pos": [
133,
3
]
} | {
"id": "C0001511",
"name": "Tissue Adhesions",
"pos": [
217,
8
]
} |
miR-103/107 expression was increased in the presence of hypoxia, thereby potentiating DAPK and KLF4 downregulation and hypoxia-induced motility and invasiveness. | NA | {
"id": 1612,
"name": "DAPK1",
"pos": [
86,
4
]
} | {
"id": "C0242184",
"name": "Hypoxia",
"pos": [
119,
7
]
} |
The ACE genotypes did not differ in terms of age, sex, body mass index, blood pressure, plasma lipids or lipoproteins. | NA | {
"id": 1636,
"name": "ACE",
"pos": [
4,
3
]
} | {
"id": "C1305855",
"name": "Body mass index",
"pos": [
55,
15
]
} |
Recently, the adenosine A2A receptor (A2AR) emerges as a novel inflammation regulator, therefore manipulation of A2AR may suppress the EMT process and as such protect against RIF. | NA | {
"id": 135,
"name": "ADORA2A",
"pos": [
113,
4
]
} | {
"id": "C0021368",
"name": "Inflammation",
"pos": [
63,
12
]
} |
Markers within GRIK2 and GRIA3 were associated with treatment-emergent suicidal ideation during citalopram therapy. | NA | {
"id": 2892,
"name": "GRIA3",
"pos": [
25,
5
]
} | {
"id": "C0424000",
"name": "Feeling suicidal (finding)",
"pos": [
71,
17
]
} |
In conclusion, these data show that during paclitaxel-induced neuropathic pain there is significant increase in GAT-1 expression in the ACC. | NA | {
"id": 10249,
"name": "GLYAT",
"pos": [
112,
3
]
} | {
"id": "C0027796",
"name": "Neuralgia",
"pos": [
62,
16
]
} |
In additional, HNSCC tumor tissue was analyzed to determine whether the wild-type p16 allele was lost or maintained. | genomic_alterations | {
"id": 1029,
"name": "CDKN2A",
"pos": [
82,
3
]
} | {
"id": "C0027651",
"name": "Neoplasms",
"pos": [
21,
5
]
} |
Stromal cell-derived factor 1α (SDF-1α) and its receptor, CXC chemokine receptor 4 (CXCR4), has been implicated as a regulator of bone resorption, suggesting that agents that can suppress SDF1α/CXCR4 signaling might inhibit osteoclastogenesis, a process closely linked to bone resorption. | NA | {
"id": 7852,
"name": "CXCR4",
"pos": [
194,
5
]
} | {
"id": "C0005974",
"name": "Bone Resorption",
"pos": [
272,
15
]
} |
As hypertension (HT) is one of the risk factors for lower urinary tract symptoms, we investigated the effect of an angiotensin II type I receptor blocker, olmesartan, on bladder dysfunction in the spontaneously hypertensive rat (SHR). | NA | {
"id": 183,
"name": "AGT",
"pos": [
115,
14
]
} | {
"id": "C0574785",
"name": "Lower Urinary Tract Symptoms",
"pos": [
52,
28
]
} |
Splicing abnormalities of CHCHD2 mutants were analysed in SH-SY5Y cells. | NA | {
"id": 51142,
"name": "CHCHD2",
"pos": [
26,
6
]
} | {
"id": "C0000768",
"name": "Congenital Abnormality",
"pos": [
9,
13
]
} |
In order to address a potential role of the interaction of p53 with MDM2 for the regulation of cellularity in atherosclerotic tissue, 22 carotid atheromatous plaques from patients undergoing endarterectomy were studied to determine the presence of p53 immunoreactivity (IR), MDM2 IR, cell proliferation as evidenced by MIB1/Ki-67 IR and DNA fragmentation by in situ terminal transferase-mediated dUTP 3' end labelling (TUNEL), as a marker for apoptosis. | NA | {
"id": 7157,
"name": "TP53",
"pos": [
248,
3
]
} | {
"id": "C0264956",
"name": "Atheroma",
"pos": [
145,
20
]
} |
In this study, we examined the expression of HOTAIR in 77 NSCLCs, their corresponding normal lung tissues and 6 brain metastases by quantitative real-time RT-PCR. | NA | {
"id": 100124700,
"name": "HOTAIR",
"pos": [
45,
6
]
} | {
"id": "C0220650",
"name": "Metastatic malignant neoplasm to brain",
"pos": [
112,
16
]
} |
These results suggest that the HLA-G 14-bp insertion/deletion polymorphism may not be associated with HCC susceptibility and liver cirrhosis development in the Korean population. | NA | {
"id": 3135,
"name": "HLA-G",
"pos": [
31,
5
]
} | {
"id": "C0023890",
"name": "Liver Cirrhosis",
"pos": [
125,
15
]
} |