|
--- |
|
license: mit |
|
configs: |
|
- config_name: dataset |
|
data_files: "dataset.csv" |
|
--- |
|
|
|
### Description |
|
This dataset contains ACE2 binding affinities of mutant SARSCoV-2 XBB.1.5 variants amino acid sequences. |
|
|
|
**Protein Format:** AA sequence |
|
|
|
### Splits |
|
traing: 3425 |
|
|
|
valid: 391 |
|
|
|
test: 386 |
|
|
|
### Related paper |
|
The dataset is from [Deep mutational scans of XBB.1.5 and BQ.1.1 reveal ongoing epistatic drift during SARSCoV-2 evolution](https://doi.org/10.1371/journal.ppat.1011901). |
|
|
|
|
|
### Label |
|
Label means delta mutation effect (ACE2 binding affinities) compre to wildtype, ranging from minus infinity to positive infinity. |
|
Zero means no affinity, lager means higher affinity and smaller means lower affinity. |
