id
stringlengths 1
4
| document_id
stringlengths 8
11
| passages
list | entities
list | events
list | coreferences
list | relations
list |
|---|---|---|---|---|---|---|
0 | 20560622:8 | [
{
"id": "1",
"type": "sentence",
"text": [
"Serum and urine biochemical parameters related to calcium status and bone metabolism remained unaltered ."
],
"offsets": [
[
0,
105
]
]
}
] | [
{
"id": "2",
"type": "outcome",
"text": [
"Serum and urine biochemical parameters related to calcium status and bone metabolism"
],
"offsets": [
[
0,
84
]
],
"normalized": []
}
] | [] | [] | [] |
3 | 19802506:6 | [
{
"id": "4",
"type": "sentence",
"text": [
"After 24 months , women who took medications without exercising had significant improvements in BMD at the total hip ( +1.81 % ) and spine ( +2.85 % ) and significant decreases in Alkphase B ( -8.7 % ) and serum NTx ( -16.7 % ) ."
],
"offsets": [
[
0,
229
]
]
}
] | [
{
"id": "5",
"type": "intervention",
"text": [
"medications"
],
"offsets": [
[
33,
44
]
],
"normalized": []
},
{
"id": "6",
"type": "intervention",
"text": [
"exercising"
],
"offsets": [
[
53,
63
]
],
"normalized": []
},
{
"id": "7",
"type": "outcome",
"text": [
"BMD"
],
"offsets": [
[
96,
99
]
],
"normalized": []
},
{
"id": "8",
"type": "outcome",
"text": [
"Alkphase B"
],
"offsets": [
[
180,
190
]
],
"normalized": []
},
{
"id": "9",
"type": "outcome",
"text": [
"serum NTx"
],
"offsets": [
[
206,
215
]
],
"normalized": []
}
] | [] | [] | [] |
10 | 23417625:10 | [
{
"id": "11",
"type": "sentence",
"text": [
"The SST-GP had higher efficacy than the LA-GP ."
],
"offsets": [
[
0,
47
]
]
}
] | [
{
"id": "12",
"type": "intervention",
"text": [
"SST-GP"
],
"offsets": [
[
4,
10
]
],
"normalized": []
},
{
"id": "13",
"type": "intervention",
"text": [
"LA-GP"
],
"offsets": [
[
40,
45
]
],
"normalized": []
},
{
"id": "14",
"type": "outcome",
"text": [
"efficacy"
],
"offsets": [
[
22,
30
]
],
"normalized": []
}
] | [] | [] | [] |
15 | 21896676:0 | [
{
"id": "16",
"type": "sentence",
"text": [
"A physiotherapy service to an emergency extended care unit does not decrease admission rates to hospital : a randomised trial ."
],
"offsets": [
[
0,
127
]
]
}
] | [
{
"id": "17",
"type": "intervention",
"text": [
"physiotherapy service"
],
"offsets": [
[
2,
23
]
],
"normalized": []
},
{
"id": "18",
"type": "outcome",
"text": [
"admission rates to hospital"
],
"offsets": [
[
77,
104
]
],
"normalized": []
}
] | [] | [] | [] |
19 | 11737955:0 | [
{
"id": "20",
"type": "sentence",
"text": [
"Antioxidant supplementation and exercise-induced oxidative stress in the 60-year-old as measured by antipyrine hydroxylates ."
],
"offsets": [
[
0,
125
]
]
}
] | [
{
"id": "21",
"type": "intervention",
"text": [
"Antioxidant supplementation"
],
"offsets": [
[
0,
27
]
],
"normalized": []
},
{
"id": "22",
"type": "intervention",
"text": [
"antipyrine hydroxylates"
],
"offsets": [
[
100,
123
]
],
"normalized": []
},
{
"id": "23",
"type": "outcome",
"text": [
"exercise-induced oxidative stress"
],
"offsets": [
[
32,
65
]
],
"normalized": []
},
{
"id": "24",
"type": "participant",
"text": [
"the 60-year-old"
],
"offsets": [
[
69,
84
]
],
"normalized": []
}
] | [] | [] | [] |
25 | 11891832:1 | [
{
"id": "26",
"type": "sentence",
"text": [
"We investigated whether 5 to 20mg per week oral methotrexate could slow down disease progression in 44 patients with inclusion body myositis in a randomized double-blind placebo-controlled study over 48 weeks ."
],
"offsets": [
[
0,
210
]
]
}
] | [
{
"id": "27",
"type": "intervention",
"text": [
"methotrexate"
],
"offsets": [
[
48,
60
]
],
"normalized": []
},
{
"id": "28",
"type": "outcome",
"text": [
"disease progression"
],
"offsets": [
[
77,
96
]
],
"normalized": []
},
{
"id": "29",
"type": "participant",
"text": [
"44 patients with inclusion body myositis"
],
"offsets": [
[
100,
140
]
],
"normalized": []
}
] | [] | [] | [] |
30 | 7853069:8 | [
{
"id": "31",
"type": "sentence",
"text": [
"The findings indicate that this method of reporting symptoms and functioning status to primary care physicians did not significantly change patient outcomes ."
],
"offsets": [
[
0,
158
]
]
}
] | [] | [] | [] | [] |
32 | 12576806:7 | [
{
"id": "33",
"type": "sentence",
"text": [
"Followup was done with diuretic scanning at 3 , 6 , 9 and 12 months and then yearly , and thereafter with diuretic renography ."
],
"offsets": [
[
0,
127
]
]
}
] | [
{
"id": "34",
"type": "outcome",
"text": [
"diuretic scanning"
],
"offsets": [
[
23,
40
]
],
"normalized": []
},
{
"id": "35",
"type": "outcome",
"text": [
"diuretic renography"
],
"offsets": [
[
106,
125
]
],
"normalized": []
}
] | [] | [] | [] |
36 | 2188766:8 | [
{
"id": "37",
"type": "sentence",
"text": [
"Trials involving larger patient populations will be necessary to confirm the results of this preliminary study and to determine the extent of clinical improvement , subpopulations benefited , role in heart failure therapeutics , and so forth ."
],
"offsets": [
[
0,
243
]
]
}
] | [] | [] | [] | [] |
38 | 7853069:5 | [
{
"id": "39",
"type": "sentence",
"text": [
"573 patients who had unrecognized and untreated anxiety identified from the approximately 8,000 patients who completed the waiting room screening questionnaire ."
],
"offsets": [
[
0,
161
]
]
}
] | [
{
"id": "40",
"type": "participant",
"text": [
"573 patients who had unrecognized and untreated anxiety identified from the approximately 8,000 patients who completed the waiting room screening questionnaire"
],
"offsets": [
[
0,
159
]
],
"normalized": []
}
] | [] | [] | [] |
41 | 12960652:0 | [
{
"id": "42",
"type": "sentence",
"text": [
"Gastric dysrhythmia in infants with gastrointestinal diseases measured by epigastric impedance ."
],
"offsets": [
[
0,
96
]
]
}
] | [
{
"id": "43",
"type": "outcome",
"text": [
"Gastric dysrhythmia"
],
"offsets": [
[
0,
19
]
],
"normalized": []
},
{
"id": "44",
"type": "outcome",
"text": [
"epigastric impedance"
],
"offsets": [
[
74,
94
]
],
"normalized": []
},
{
"id": "45",
"type": "participant",
"text": [
"infants with gastrointestinal diseases"
],
"offsets": [
[
23,
61
]
],
"normalized": []
}
] | [] | [] | [] |
46 | 12595499:10 | [
{
"id": "47",
"type": "sentence",
"text": [
"Microalbuminuria itself predicts clinical proteinuria in nondiabetic and in diabetic people ."
],
"offsets": [
[
0,
93
]
]
}
] | [
{
"id": "48",
"type": "outcome",
"text": [
"clinical proteinuria"
],
"offsets": [
[
33,
53
]
],
"normalized": []
},
{
"id": "49",
"type": "participant",
"text": [
"nondiabetic and in diabetic people"
],
"offsets": [
[
57,
91
]
],
"normalized": []
}
] | [] | [] | [] |
50 | 23021296:2 | [
{
"id": "51",
"type": "sentence",
"text": [
"However , there is a lack of information regarding patient 's adherence to these recommendations in daily clinical practice ."
],
"offsets": [
[
0,
125
]
]
}
] | [
{
"id": "52",
"type": "outcome",
"text": [
"patient 's adherence"
],
"offsets": [
[
51,
71
]
],
"normalized": []
}
] | [] | [] | [] |
53 | 11495215:1 | [
{
"id": "54",
"type": "sentence",
"text": [
"Women who smoke and take oral contraceptives ( OCs ) have significantly increased risk of cardiovascular disease , but the exact mechanismsfor the increased risk are not known ."
],
"offsets": [
[
0,
177
]
]
}
] | [
{
"id": "55",
"type": "intervention",
"text": [
"oral contraceptives ( OCs )"
],
"offsets": [
[
25,
52
]
],
"normalized": []
},
{
"id": "56",
"type": "outcome",
"text": [
"cardiovascular disease"
],
"offsets": [
[
90,
112
]
],
"normalized": []
}
] | [] | [] | [] |
57 | 11750293:4 | [
{
"id": "58",
"type": "sentence",
"text": [
"Patients became significantly more depressed over time ."
],
"offsets": [
[
0,
56
]
]
}
] | [] | [] | [] | [] |
59 | 11891832:0 | [
{
"id": "60",
"type": "sentence",
"text": [
"Comparison of weakness progression in inclusion body myositis during treatment with methotrexate or placebo ."
],
"offsets": [
[
0,
109
]
]
}
] | [
{
"id": "61",
"type": "intervention",
"text": [
"methotrexate"
],
"offsets": [
[
84,
96
]
],
"normalized": []
},
{
"id": "62",
"type": "intervention",
"text": [
"placebo"
],
"offsets": [
[
100,
107
]
],
"normalized": []
},
{
"id": "63",
"type": "outcome",
"text": [
"weakness progression"
],
"offsets": [
[
14,
34
]
],
"normalized": []
},
{
"id": "64",
"type": "participant",
"text": [
"inclusion body myositis"
],
"offsets": [
[
38,
61
]
],
"normalized": []
}
] | [] | [] | [] |
65 | 18503531:6 | [
{
"id": "66",
"type": "sentence",
"text": [
"Treatment group participants were better able to suggest appropriate emotion-management strategies for story characters at post-intervention than at pre-intervention , whereas control participants were not ."
],
"offsets": [
[
0,
207
]
]
}
] | [
{
"id": "67",
"type": "outcome",
"text": [
"emotion-management strategies"
],
"offsets": [
[
69,
98
]
],
"normalized": []
}
] | [] | [] | [] |
68 | 6421395:4 | [
{
"id": "69",
"type": "sentence",
"text": [
"The increase in plasma 6-keto-prostaglandin F1 alpha concentration was associated with an increase in serum HDL2 cholesterol concentration in the group taking regular exercise ."
],
"offsets": [
[
0,
177
]
]
}
] | [
{
"id": "70",
"type": "intervention",
"text": [
"regular exercise"
],
"offsets": [
[
159,
175
]
],
"normalized": []
},
{
"id": "71",
"type": "outcome",
"text": [
"plasma 6-keto-prostaglandin F1 alpha concentration"
],
"offsets": [
[
16,
66
]
],
"normalized": []
},
{
"id": "72",
"type": "outcome",
"text": [
"serum HDL2 cholesterol concentration"
],
"offsets": [
[
102,
138
]
],
"normalized": []
}
] | [] | [] | [] |
73 | 21170734:3 | [
{
"id": "74",
"type": "sentence",
"text": [
"Results showed that cortisol and glucose levels were significantly high in 700 and 500 but not 3,000 mg l⁻¹ group compared to control ."
],
"offsets": [
[
0,
135
]
]
}
] | [
{
"id": "75",
"type": "outcome",
"text": [
"cortisol and glucose levels"
],
"offsets": [
[
20,
47
]
],
"normalized": []
}
] | [] | [] | [] |
76 | 21170734:7 | [
{
"id": "77",
"type": "sentence",
"text": [
"Results suggest that rapid anesthesia with higher dose is better than slow anesthesia with lower dose for blood sampling in Beluga ."
],
"offsets": [
[
0,
132
]
]
}
] | [
{
"id": "78",
"type": "intervention",
"text": [
"anesthesia"
],
"offsets": [
[
27,
37
]
],
"normalized": []
},
{
"id": "79",
"type": "intervention",
"text": [
"anesthesia"
],
"offsets": [
[
27,
37
]
],
"normalized": []
},
{
"id": "80",
"type": "outcome",
"text": [
"blood sampling"
],
"offsets": [
[
106,
120
]
],
"normalized": []
},
{
"id": "81",
"type": "participant",
"text": [
"Beluga"
],
"offsets": [
[
124,
130
]
],
"normalized": []
}
] | [] | [] | [] |
82 | 18337284:7 | [
{
"id": "83",
"type": "sentence",
"text": [
"GABHS isolates were serotyped to distinguish bacteriological treatment failures ( and relapses ) from new acquisitions ."
],
"offsets": [
[
0,
120
]
]
}
] | [
{
"id": "84",
"type": "outcome",
"text": [
"GABHS isolates were serotyped"
],
"offsets": [
[
0,
29
]
],
"normalized": []
},
{
"id": "85",
"type": "outcome",
"text": [
"bacteriological treatment failures"
],
"offsets": [
[
45,
79
]
],
"normalized": []
},
{
"id": "86",
"type": "outcome",
"text": [
"relapses"
],
"offsets": [
[
86,
94
]
],
"normalized": []
},
{
"id": "87",
"type": "outcome",
"text": [
"new acquisitions"
],
"offsets": [
[
102,
118
]
],
"normalized": []
}
] | [] | [] | [] |
88 | 12576806:12 | [
{
"id": "89",
"type": "sentence",
"text": [
"This difference was not significant ."
],
"offsets": [
[
0,
37
]
]
}
] | [] | [] | [] | [] |
90 | 11495215:10 | [
{
"id": "91",
"type": "sentence",
"text": [
"These data show that acute nicotine administration , in the form of nicotine gum , has no effect on cardiovascular or lipid stress reactivity in women ."
],
"offsets": [
[
0,
152
]
]
}
] | [
{
"id": "92",
"type": "intervention",
"text": [
"nicotine"
],
"offsets": [
[
27,
35
]
],
"normalized": []
},
{
"id": "93",
"type": "intervention",
"text": [
"nicotine"
],
"offsets": [
[
27,
35
]
],
"normalized": []
},
{
"id": "94",
"type": "outcome",
"text": [
"cardiovascular or lipid stress reactivity"
],
"offsets": [
[
100,
141
]
],
"normalized": []
},
{
"id": "95",
"type": "participant",
"text": [
"women"
],
"offsets": [
[
145,
150
]
],
"normalized": []
}
] | [] | [] | [] |
96 | 23417625:5 | [
{
"id": "97",
"type": "sentence",
"text": [
"Participants were randomized to the SST or LA group ."
],
"offsets": [
[
0,
53
]
]
}
] | [
{
"id": "98",
"type": "intervention",
"text": [
"SST"
],
"offsets": [
[
36,
39
]
],
"normalized": []
},
{
"id": "99",
"type": "intervention",
"text": [
"LA"
],
"offsets": [
[
43,
45
]
],
"normalized": []
}
] | [] | [] | [] |
100 | 10390665:4 | [
{
"id": "101",
"type": "sentence",
"text": [
"A complete response , defined as no emesis with no need for another rescue antiemetic , during the first 3 h ( 0-3 h ) after anesthesia was 87 % with granisetron and 78 % with perphenazine ( P = 0.204 ) ."
],
"offsets": [
[
0,
204
]
]
}
] | [
{
"id": "102",
"type": "intervention",
"text": [
"granisetron"
],
"offsets": [
[
150,
161
]
],
"normalized": []
},
{
"id": "103",
"type": "intervention",
"text": [
"perphenazine"
],
"offsets": [
[
176,
188
]
],
"normalized": []
},
{
"id": "104",
"type": "outcome",
"text": [
"complete response , defined as no emesis with no need for another rescue antiemetic"
],
"offsets": [
[
2,
85
]
],
"normalized": []
}
] | [] | [] | [] |
105 | 20618920:0 | [
{
"id": "106",
"type": "sentence",
"text": [
"Effectiveness of hygienic-dietary recommendations as enhancers of antidepressant treatment in patients with depression : study protocol of a randomized controlled trial ."
],
"offsets": [
[
0,
170
]
]
}
] | [
{
"id": "107",
"type": "intervention",
"text": [
"hygienic-dietary recommendations"
],
"offsets": [
[
17,
49
]
],
"normalized": []
},
{
"id": "108",
"type": "outcome",
"text": [
"Effectiveness"
],
"offsets": [
[
0,
13
]
],
"normalized": []
},
{
"id": "109",
"type": "participant",
"text": [
"patients with depression"
],
"offsets": [
[
94,
118
]
],
"normalized": []
}
] | [] | [] | [] |
110 | 24515505:2 | [
{
"id": "111",
"type": "sentence",
"text": [
"We used national data from the Medical Expenditure Panel Survey linked to the National Health Interview Survey and a study-specific survey to estimate the annual utilization and costs for health care , school , ASD-related therapy , family-coordinated services , as well as caregiver time in children aged 3 to 17 years , with and without parent-reported ASD ."
],
"offsets": [
[
0,
360
]
]
}
] | [
{
"id": "112",
"type": "outcome",
"text": [
"annual utilization and costs for health care , school , ASD-related therapy , family-coordinated services , as well as caregiver time"
],
"offsets": [
[
155,
288
]
],
"normalized": []
},
{
"id": "113",
"type": "participant",
"text": [
"children aged 3 to 17 years , with and without parent-reported ASD ."
],
"offsets": [
[
292,
360
]
],
"normalized": []
}
] | [] | [] | [] |
114 | 9816035:5 | [
{
"id": "115",
"type": "sentence",
"text": [
"Amonafide was chosen for inclusion in the Cancer and Leukemia Group B ( CALGB ) master metastatic breast cancer protocol ."
],
"offsets": [
[
0,
122
]
]
}
] | [
{
"id": "116",
"type": "intervention",
"text": [
"Amonafide"
],
"offsets": [
[
0,
9
]
],
"normalized": []
}
] | [] | [] | [] |
117 | 18337284:14 | [
{
"id": "118",
"type": "sentence",
"text": [
"In this adequately powered study , once-daily oral amoxicillin is not inferior to twice-daily penicillin V for the treatment and eradication of GABHS in children with pharyngitis ."
],
"offsets": [
[
0,
180
]
]
}
] | [
{
"id": "119",
"type": "intervention",
"text": [
"amoxicillin"
],
"offsets": [
[
51,
62
]
],
"normalized": []
},
{
"id": "120",
"type": "intervention",
"text": [
"penicillin"
],
"offsets": [
[
94,
104
]
],
"normalized": []
},
{
"id": "121",
"type": "outcome",
"text": [
"not inferior"
],
"offsets": [
[
66,
78
]
],
"normalized": []
},
{
"id": "122",
"type": "participant",
"text": [
"GABHS in children with pharyngitis"
],
"offsets": [
[
144,
178
]
],
"normalized": []
}
] | [] | [] | [] |
123 | 23356250:4 | [
{
"id": "124",
"type": "sentence",
"text": [
"In this preliminary , open-labeled , randomized study , the effects of lime juice on the clinical and some laboratory characteristics of children with SCA were tested ."
],
"offsets": [
[
0,
168
]
]
}
] | [
{
"id": "125",
"type": "intervention",
"text": [
"lime juice"
],
"offsets": [
[
71,
81
]
],
"normalized": []
},
{
"id": "126",
"type": "outcome",
"text": [
"clinical and some laboratory characteristics"
],
"offsets": [
[
89,
133
]
],
"normalized": []
},
{
"id": "127",
"type": "participant",
"text": [
"children with SCA"
],
"offsets": [
[
137,
154
]
],
"normalized": []
}
] | [] | [] | [] |
128 | 9816035:2 | [
{
"id": "129",
"type": "sentence",
"text": [
"The drug had demonstrated significant activity in preclinical studies and some activity in Phase I trials ."
],
"offsets": [
[
0,
107
]
]
}
] | [] | [] | [] | [] |
130 | 12595499:11 | [
{
"id": "131",
"type": "sentence",
"text": [
"Ramipril prevents or delays the progression of albuminuria ."
],
"offsets": [
[
0,
60
]
]
}
] | [
{
"id": "132",
"type": "intervention",
"text": [
"Ramipril"
],
"offsets": [
[
0,
8
]
],
"normalized": []
},
{
"id": "133",
"type": "outcome",
"text": [
"progression of albuminuria"
],
"offsets": [
[
32,
58
]
],
"normalized": []
}
] | [] | [] | [] |
134 | 16505427:1 | [
{
"id": "135",
"type": "sentence",
"text": [
"To compare maintenance epoetin alfa administered once every 3 weeks with continued weekly epoetin alfa for patients with cancer-associated anemia ."
],
"offsets": [
[
0,
147
]
]
}
] | [
{
"id": "136",
"type": "intervention",
"text": [
"epoetin alfa"
],
"offsets": [
[
23,
35
]
],
"normalized": []
},
{
"id": "137",
"type": "intervention",
"text": [
"epoetin alfa"
],
"offsets": [
[
23,
35
]
],
"normalized": []
},
{
"id": "138",
"type": "participant",
"text": [
"patients with cancer-associated anemia"
],
"offsets": [
[
107,
145
]
],
"normalized": []
}
] | [] | [] | [] |
139 | 12960652:3 | [
{
"id": "140",
"type": "sentence",
"text": [
"Epigastric impedance is a non-invasive method used to study gastric emptying time and gastric phasic activity ."
],
"offsets": [
[
0,
111
]
]
}
] | [
{
"id": "141",
"type": "intervention",
"text": [
"Epigastric impedance"
],
"offsets": [
[
0,
20
]
],
"normalized": []
},
{
"id": "142",
"type": "outcome",
"text": [
"Epigastric impedance"
],
"offsets": [
[
0,
20
]
],
"normalized": []
},
{
"id": "143",
"type": "outcome",
"text": [
"gastric emptying time and gastric phasic activity"
],
"offsets": [
[
60,
109
]
],
"normalized": []
}
] | [] | [] | [] |
144 | 23849147:0 | [
{
"id": "145",
"type": "sentence",
"text": [
"Bayesian adaptive trials offer advantages in comparative effectiveness trials : an example in status epilepticus ."
],
"offsets": [
[
0,
114
]
]
}
] | [
{
"id": "146",
"type": "intervention",
"text": [
"Bayesian adaptive trials"
],
"offsets": [
[
0,
24
]
],
"normalized": []
},
{
"id": "147",
"type": "outcome",
"text": [
"effectiveness"
],
"offsets": [
[
57,
70
]
],
"normalized": []
},
{
"id": "148",
"type": "participant",
"text": [
"status epilepticus"
],
"offsets": [
[
94,
112
]
],
"normalized": []
}
] | [] | [] | [] |
149 | 2188766:1 | [
{
"id": "150",
"type": "sentence",
"text": [
"This study was conducted to determine the long-term effect of flosequinan , a new orally administered arterial and venous dilator , on the clinical course of patients with moderate to severe congestive heart failure ."
],
"offsets": [
[
0,
217
]
]
}
] | [
{
"id": "151",
"type": "intervention",
"text": [
"flosequinan"
],
"offsets": [
[
62,
73
]
],
"normalized": []
},
{
"id": "152",
"type": "outcome",
"text": [
"long-term effect"
],
"offsets": [
[
42,
58
]
],
"normalized": []
},
{
"id": "153",
"type": "outcome",
"text": [
"clinical course"
],
"offsets": [
[
139,
154
]
],
"normalized": []
},
{
"id": "154",
"type": "participant",
"text": [
"patients with moderate to severe congestive heart failure"
],
"offsets": [
[
158,
215
]
],
"normalized": []
}
] | [] | [] | [] |
155 | 23356250:2 | [
{
"id": "156",
"type": "sentence",
"text": [
"Intake of lime juice was recently demonstrated to facilitate clearance of the malaria parasite ."
],
"offsets": [
[
0,
96
]
]
}
] | [
{
"id": "157",
"type": "intervention",
"text": [
"lime juice"
],
"offsets": [
[
10,
20
]
],
"normalized": []
}
] | [] | [] | [] |
158 | 11737955:2 | [
{
"id": "159",
"type": "sentence",
"text": [
"Subjects were randomly divided in two groups : supplementation ( n 11 ) with 100 mg dl-alpha-tocopheryl acetate , 200 mg ascorbic acid , and 2 mg beta-carotene , and placebo ( n 9 ) ."
],
"offsets": [
[
0,
183
]
]
}
] | [
{
"id": "160",
"type": "intervention",
"text": [
"dl-alpha-tocopheryl acetate"
],
"offsets": [
[
84,
111
]
],
"normalized": []
},
{
"id": "161",
"type": "intervention",
"text": [
"ascorbic acid"
],
"offsets": [
[
121,
134
]
],
"normalized": []
},
{
"id": "162",
"type": "intervention",
"text": [
"beta-carotene"
],
"offsets": [
[
146,
159
]
],
"normalized": []
},
{
"id": "163",
"type": "intervention",
"text": [
"placebo"
],
"offsets": [
[
166,
173
]
],
"normalized": []
}
] | [] | [] | [] |
164 | 2188766:7 | [
{
"id": "165",
"type": "sentence",
"text": [
"The addition of chronic vasodilator therapy with flosequinan to standard digitalis-diuretic regimens is capable of inducing clinical improvement in patients with moderate to severe chronic heart failure ."
],
"offsets": [
[
0,
204
]
]
}
] | [
{
"id": "166",
"type": "intervention",
"text": [
"flosequinan"
],
"offsets": [
[
49,
60
]
],
"normalized": []
},
{
"id": "167",
"type": "participant",
"text": [
"patients with moderate to severe chronic heart failure"
],
"offsets": [
[
148,
202
]
],
"normalized": []
}
] | [] | [] | [] |
168 | 18337284:6 | [
{
"id": "169",
"type": "sentence",
"text": [
"Eradication of GABHS , determined with follow-up throat cultures on days 3-6 , 12-16 and 26-36 ."
],
"offsets": [
[
0,
96
]
]
}
] | [
{
"id": "170",
"type": "outcome",
"text": [
"Eradication of GABHS ,"
],
"offsets": [
[
0,
22
]
],
"normalized": []
},
{
"id": "171",
"type": "outcome",
"text": [
"follow-up throat cultures"
],
"offsets": [
[
39,
64
]
],
"normalized": []
}
] | [] | [] | [] |
172 | 18337284:1 | [
{
"id": "173",
"type": "sentence",
"text": [
"Rheumatic fever is a preventable chronic disease preceded by group A beta-haemolytic streptococcal ( GABHS ) pharyngitis ."
],
"offsets": [
[
0,
122
]
]
}
] | [] | [] | [] | [] |
174 | 2188766:4 | [
{
"id": "175",
"type": "sentence",
"text": [
"During the course of therapy , a modest improvement in the symptom scores and functional classification of the flosequinan-treated patients was observed ."
],
"offsets": [
[
0,
154
]
]
}
] | [
{
"id": "176",
"type": "intervention",
"text": [
"flosequinan-treated"
],
"offsets": [
[
111,
130
]
],
"normalized": []
},
{
"id": "177",
"type": "outcome",
"text": [
"symptom scores and functional classification"
],
"offsets": [
[
59,
103
]
],
"normalized": []
}
] | [] | [] | [] |
178 | 9816035:8 | [
{
"id": "179",
"type": "sentence",
"text": [
"This report deals only with amonafide as a Phase II agent ."
],
"offsets": [
[
0,
59
]
]
}
] | [
{
"id": "180",
"type": "intervention",
"text": [
"amonafide"
],
"offsets": [
[
28,
37
]
],
"normalized": []
}
] | [] | [] | [] |
181 | 18503531:7 | [
{
"id": "182",
"type": "sentence",
"text": [
"However , there was no difference in the improvements made by children in the intervention and control conditions on facial expression and body-posture recognition measures ."
],
"offsets": [
[
0,
174
]
]
}
] | [
{
"id": "183",
"type": "outcome",
"text": [
"facial expression and body-posture recognition measures"
],
"offsets": [
[
117,
172
]
],
"normalized": []
}
] | [] | [] | [] |
184 | 20560622:3 | [
{
"id": "185",
"type": "sentence",
"text": [
"In a 2 week randomized two-period crossover trial , 18 male adolescents consumed two diets , named white diet ( WD ) and brown diet ( BD ) , which were poor and rich in MRP , respectively ."
],
"offsets": [
[
0,
189
]
]
}
] | [
{
"id": "186",
"type": "intervention",
"text": [
"white diet ( WD )"
],
"offsets": [
[
99,
116
]
],
"normalized": []
},
{
"id": "187",
"type": "intervention",
"text": [
"brown diet ( BD )"
],
"offsets": [
[
121,
138
]
],
"normalized": []
},
{
"id": "188",
"type": "intervention",
"text": [
"MRP"
],
"offsets": [
[
169,
172
]
],
"normalized": []
},
{
"id": "189",
"type": "participant",
"text": [
"18 male adolescents"
],
"offsets": [
[
52,
71
]
],
"normalized": []
}
] | [] | [] | [] |
190 | 17321989:6 | [
{
"id": "191",
"type": "sentence",
"text": [
"Our results suggest that both drugs were well tolerated in patients with AML or MDS who received chemotherapy and that the efficacy of itraconazole for prophylaxis against systemic fungal disease is not inferior to that of fluconazole ."
],
"offsets": [
[
0,
236
]
]
}
] | [
{
"id": "192",
"type": "intervention",
"text": [
"itraconazole"
],
"offsets": [
[
135,
147
]
],
"normalized": []
},
{
"id": "193",
"type": "intervention",
"text": [
"fluconazole"
],
"offsets": [
[
223,
234
]
],
"normalized": []
},
{
"id": "194",
"type": "outcome",
"text": [
"efficacy"
],
"offsets": [
[
123,
131
]
],
"normalized": []
},
{
"id": "195",
"type": "participant",
"text": [
"patients with AML or MDS who received chemotherapy"
],
"offsets": [
[
59,
109
]
],
"normalized": []
}
] | [] | [] | [] |
196 | 12595499:6 | [
{
"id": "197",
"type": "sentence",
"text": [
"Baseline microalbuminuria predicted subsequent clinical proteinuria for the study participants overall ( adjusted odds ratio [ OR ] , 17.5 ; 95 % confidence interval [ CI ] , 12.6 to 24.4 ) , in participants without diabetes ( OR , 16.7 ; 95 % CI , 8.6 to 32.4 ) , and in participants with diabetes ( OR , 18.2 ; 95 % CI , 12.4 to 26.7 ) ."
],
"offsets": [
[
0,
339
]
]
}
] | [
{
"id": "198",
"type": "outcome",
"text": [
"clinical proteinuria"
],
"offsets": [
[
47,
67
]
],
"normalized": []
}
] | [] | [] | [] |
199 | 11317090:9 | [
{
"id": "200",
"type": "sentence",
"text": [
"Nonparametric bootstrap sampling of costs/QALY ratios established the 95 % CI around the estimates ."
],
"offsets": [
[
0,
100
]
]
}
] | [
{
"id": "201",
"type": "outcome",
"text": [
"Nonparametric bootstrap sampling of costs/QALY ratios"
],
"offsets": [
[
0,
53
]
],
"normalized": []
}
] | [] | [] | [] |
202 | 21106663:7 | [
{
"id": "203",
"type": "sentence",
"text": [
"MLMs indicated a slight increase in depressive symptoms over time in the sample as a whole ."
],
"offsets": [
[
0,
92
]
]
}
] | [
{
"id": "204",
"type": "outcome",
"text": [
"depressive symptoms"
],
"offsets": [
[
36,
55
]
],
"normalized": []
}
] | [] | [] | [] |
205 | 11317090:10 | [
{
"id": "206",
"type": "sentence",
"text": [
"Aquatic exercisers reported equal ( QWB ) or better ( CHDR , HAQ , PQOL ) health-related quality of life compared with controls ."
],
"offsets": [
[
0,
129
]
]
}
] | [
{
"id": "207",
"type": "intervention",
"text": [
"Aquatic exercisers"
],
"offsets": [
[
0,
18
]
],
"normalized": []
},
{
"id": "208",
"type": "outcome",
"text": [
"QWB"
],
"offsets": [
[
36,
39
]
],
"normalized": []
},
{
"id": "209",
"type": "outcome",
"text": [
"CHDR , HAQ , PQOL"
],
"offsets": [
[
54,
71
]
],
"normalized": []
}
] | [] | [] | [] |
210 | 6421395:2 | [
{
"id": "211",
"type": "sentence",
"text": [
"In the men taking regular exercise serum cholesterol concentrations increased 26 % more in the high density lipoprotein subfraction two ( HDL2 ) and decreased 31 % more in the subfraction three ( HDL3 ) and 9 % more in the low density lipoprotein fraction than in the control group ."
],
"offsets": [
[
0,
283
]
]
}
] | [
{
"id": "212",
"type": "intervention",
"text": [
"regular exercise"
],
"offsets": [
[
18,
34
]
],
"normalized": []
},
{
"id": "213",
"type": "outcome",
"text": [
"serum cholesterol concentrations"
],
"offsets": [
[
35,
67
]
],
"normalized": []
},
{
"id": "214",
"type": "outcome",
"text": [
"high density lipoprotein subfraction two ( HDL2 )"
],
"offsets": [
[
95,
144
]
],
"normalized": []
},
{
"id": "215",
"type": "outcome",
"text": [
"subfraction three ( HDL3 )"
],
"offsets": [
[
176,
202
]
],
"normalized": []
},
{
"id": "216",
"type": "outcome",
"text": [
"low density lipoprotein fraction"
],
"offsets": [
[
223,
255
]
],
"normalized": []
}
] | [] | [] | [] |
217 | 11317090:11 | [
{
"id": "218",
"type": "sentence",
"text": [
"Outcomes improved with regular class attendance ."
],
"offsets": [
[
0,
49
]
]
}
] | [] | [] | [] | [] |
219 | 12595499:7 | [
{
"id": "220",
"type": "sentence",
"text": [
"Any progression of albuminuria ( defined as new microalbuminuria or new clinical proteinuria ) occurred in 1859 participants ; 1542 developed new microalbuminuria , and 317 participants developed clinical proteinuria ."
],
"offsets": [
[
0,
218
]
]
}
] | [
{
"id": "221",
"type": "outcome",
"text": [
"progression of albuminuria"
],
"offsets": [
[
4,
30
]
],
"normalized": []
},
{
"id": "222",
"type": "outcome",
"text": [
"new microalbuminuria or new clinical proteinuria"
],
"offsets": [
[
44,
92
]
],
"normalized": []
},
{
"id": "223",
"type": "outcome",
"text": [
"new microalbuminuria"
],
"offsets": [
[
44,
64
]
],
"normalized": []
},
{
"id": "224",
"type": "outcome",
"text": [
"clinical proteinuria"
],
"offsets": [
[
72,
92
]
],
"normalized": []
}
] | [] | [] | [] |
225 | 7853069:2 | [
{
"id": "226",
"type": "sentence",
"text": [
"Participating physicians were randomized to either the demonstration or the control arm , and patients were assigned to a study arm based on the randomization of their physicians ."
],
"offsets": [
[
0,
180
]
]
}
] | [
{
"id": "227",
"type": "intervention",
"text": [
"demonstration"
],
"offsets": [
[
55,
68
]
],
"normalized": []
}
] | [] | [] | [] |
228 | 11495215:5 | [
{
"id": "229",
"type": "sentence",
"text": [
"Approximately two thirds were smokers and were randomized to be tested after either a 12-hr nicotine deprivation or administration of nicotine gum ."
],
"offsets": [
[
0,
148
]
]
}
] | [
{
"id": "230",
"type": "intervention",
"text": [
"nicotine deprivation"
],
"offsets": [
[
92,
112
]
],
"normalized": []
},
{
"id": "231",
"type": "intervention",
"text": [
"nicotine"
],
"offsets": [
[
92,
100
]
],
"normalized": []
},
{
"id": "232",
"type": "participant",
"text": [
"two thirds were smokers"
],
"offsets": [
[
14,
37
]
],
"normalized": []
}
] | [] | [] | [] |
233 | 20560622:2 | [
{
"id": "234",
"type": "sentence",
"text": [
"The effects of the high intake of Maillard reaction products ( MRP ) on calcium availability in adolescents and across Caco-2 cell monolayers were examined ."
],
"offsets": [
[
0,
157
]
]
}
] | [
{
"id": "235",
"type": "intervention",
"text": [
"Maillard reaction products ( MRP )"
],
"offsets": [
[
34,
68
]
],
"normalized": []
},
{
"id": "236",
"type": "outcome",
"text": [
"calcium availability"
],
"offsets": [
[
72,
92
]
],
"normalized": []
},
{
"id": "237",
"type": "participant",
"text": [
"adolescents"
],
"offsets": [
[
96,
107
]
],
"normalized": []
}
] | [] | [] | [] |
238 | 24515505:9 | [
{
"id": "239",
"type": "sentence",
"text": [
"Previous analyses that focused on health care underestimated this economic burden , particularly for school systems ."
],
"offsets": [
[
0,
117
]
]
}
] | [
{
"id": "240",
"type": "outcome",
"text": [
"economic burden"
],
"offsets": [
[
66,
81
]
],
"normalized": []
}
] | [] | [] | [] |
241 | 23103798:0 | [
{
"id": "242",
"type": "sentence",
"text": [
"Role of posterior tibial nerve stimulation in the treatment of refractory monosymptomatic nocturnal enuresis : a pilot study ."
],
"offsets": [
[
0,
126
]
]
}
] | [
{
"id": "243",
"type": "intervention",
"text": [
"posterior tibial nerve stimulation"
],
"offsets": [
[
8,
42
]
],
"normalized": []
},
{
"id": "244",
"type": "participant",
"text": [
"refractory monosymptomatic nocturnal enuresis"
],
"offsets": [
[
63,
108
]
],
"normalized": []
}
] | [] | [] | [] |
245 | 23103798:13 | [
{
"id": "246",
"type": "sentence",
"text": [
"No change was evident in group 2 ."
],
"offsets": [
[
0,
34
]
]
}
] | [] | [] | [] | [] |
247 | 18845996:1 | [
{
"id": "248",
"type": "sentence",
"text": [
"To develop a cycle-based risk prediction model for neutropenic complications ( NC ) during chemotherapy with doxorubicin ( DOX ) or a pegylated liposomal formulation ( PLD ) for patients with metastatic breast cancer ( MBC ) ."
],
"offsets": [
[
0,
226
]
]
}
] | [
{
"id": "249",
"type": "intervention",
"text": [
"doxorubicin ( DOX )"
],
"offsets": [
[
109,
128
]
],
"normalized": []
},
{
"id": "250",
"type": "intervention",
"text": [
"pegylated liposomal formulation ( PLD )"
],
"offsets": [
[
134,
173
]
],
"normalized": []
},
{
"id": "251",
"type": "outcome",
"text": [
"cycle-based risk prediction model for neutropenic complications ( NC )"
],
"offsets": [
[
13,
83
]
],
"normalized": []
},
{
"id": "252",
"type": "participant",
"text": [
"patients with metastatic breast cancer ( MBC )"
],
"offsets": [
[
178,
224
]
],
"normalized": []
}
] | [] | [] | [] |
253 | 16505427:5 | [
{
"id": "254",
"type": "sentence",
"text": [
"There was no difference in the proportion of patients requiring transfusions during the study ( 23 % in 40K arm and 18 % in 120K arm , P = .22 ) or specifically during the maintenance phase ( 13 % in 40K arm v 15 % in 120K arm , P = .58 ) ."
],
"offsets": [
[
0,
240
]
]
}
] | [
{
"id": "255",
"type": "outcome",
"text": [
"requiring transfusions"
],
"offsets": [
[
54,
76
]
],
"normalized": []
}
] | [] | [] | [] |
256 | 24803369:2 | [
{
"id": "257",
"type": "sentence",
"text": [
"However , no study to date has examined whether or not they understand conceptual metaphors ( i.e . mappings between conceptual structures ) , which could be the building blocks of metaphoric thinking and understanding ."
],
"offsets": [
[
0,
220
]
]
}
] | [
{
"id": "258",
"type": "intervention",
"text": [
"conceptual metaphors"
],
"offsets": [
[
71,
91
]
],
"normalized": []
},
{
"id": "259",
"type": "outcome",
"text": [
"conceptual metaphors"
],
"offsets": [
[
71,
91
]
],
"normalized": []
}
] | [] | [] | [] |
260 | 23021296:0 | [
{
"id": "261",
"type": "sentence",
"text": [
"Adherence to lifestyle recommendations by patients with depression ."
],
"offsets": [
[
0,
68
]
]
}
] | [
{
"id": "262",
"type": "intervention",
"text": [
"lifestyle recommendations"
],
"offsets": [
[
13,
38
]
],
"normalized": []
},
{
"id": "263",
"type": "outcome",
"text": [
"Adherence"
],
"offsets": [
[
0,
9
]
],
"normalized": []
},
{
"id": "264",
"type": "participant",
"text": [
"patients with depression"
],
"offsets": [
[
42,
66
]
],
"normalized": []
}
] | [] | [] | [] |
265 | 2224060:3 | [
{
"id": "266",
"type": "sentence",
"text": [
"After induction of complete remission , patients were randomized to the bestatin group ( 30 mg/bw per os ( po ) daily ) and the control group ."
],
"offsets": [
[
0,
143
]
]
}
] | [
{
"id": "267",
"type": "intervention",
"text": [
"bestatin"
],
"offsets": [
[
72,
80
]
],
"normalized": []
}
] | [] | [] | [] |
268 | 2224060:4 | [
{
"id": "269",
"type": "sentence",
"text": [
"The 101 eligible cases ( bestatin : 48 , control : 53 ) were analyzed ; the bestatin group achieved longer remission than the control group and a statistically significant longer survival ."
],
"offsets": [
[
0,
189
]
]
}
] | [
{
"id": "270",
"type": "intervention",
"text": [
"bestatin"
],
"offsets": [
[
25,
33
]
],
"normalized": []
},
{
"id": "271",
"type": "intervention",
"text": [
"bestatin"
],
"offsets": [
[
25,
33
]
],
"normalized": []
},
{
"id": "272",
"type": "outcome",
"text": [
"longer remission"
],
"offsets": [
[
100,
116
]
],
"normalized": []
},
{
"id": "273",
"type": "outcome",
"text": [
"longer survival"
],
"offsets": [
[
172,
187
]
],
"normalized": []
},
{
"id": "274",
"type": "participant",
"text": [
"The 101 eligible cases ( bestatin : 48 , control : 53 )"
],
"offsets": [
[
0,
55
]
],
"normalized": []
}
] | [] | [] | [] |
275 | 24726342:8 | [
{
"id": "276",
"type": "sentence",
"text": [
"In assessing the acute functional effect of bronchodilators , ΔsRAW-based criterion is preferable to FEV1-FVC-based criteria , being more closely related to bronchodilator-induced improvements of lung mechanics and dyspnea at rest ."
],
"offsets": [
[
0,
232
]
]
}
] | [
{
"id": "277",
"type": "intervention",
"text": [
"bronchodilators"
],
"offsets": [
[
44,
59
]
],
"normalized": []
},
{
"id": "278",
"type": "intervention",
"text": [
"bronchodilator-induced"
],
"offsets": [
[
157,
179
]
],
"normalized": []
},
{
"id": "279",
"type": "outcome",
"text": [
"improvements of lung mechanics and dyspnea at rest"
],
"offsets": [
[
180,
230
]
],
"normalized": []
}
] | [] | [] | [] |
280 | 2678230:0 | [
{
"id": "281",
"type": "sentence",
"text": [
"[ The effect of ionic and nonionic x-ray contrast media on myocardial perfusion and myocardial function ] ."
],
"offsets": [
[
0,
107
]
]
}
] | [
{
"id": "282",
"type": "intervention",
"text": [
"ionic"
],
"offsets": [
[
16,
21
]
],
"normalized": []
},
{
"id": "283",
"type": "intervention",
"text": [
"nonionic x-ray contrast"
],
"offsets": [
[
26,
49
]
],
"normalized": []
},
{
"id": "284",
"type": "outcome",
"text": [
"myocardial perfusion and myocardial function"
],
"offsets": [
[
59,
103
]
],
"normalized": []
}
] | [] | [] | [] |
285 | 22865017:2 | [
{
"id": "286",
"type": "sentence",
"text": [
"To compare a collaborative approach , the Three Component Model ( 3CM ) , with usual care for treating PTSD in primary care ."
],
"offsets": [
[
0,
125
]
]
}
] | [
{
"id": "287",
"type": "intervention",
"text": [
"Three Component Model ( 3CM )"
],
"offsets": [
[
42,
71
]
],
"normalized": []
},
{
"id": "288",
"type": "intervention",
"text": [
"usual care"
],
"offsets": [
[
79,
89
]
],
"normalized": []
},
{
"id": "289",
"type": "participant",
"text": [
"PTSD"
],
"offsets": [
[
103,
107
]
],
"normalized": []
}
] | [] | [] | [] |
290 | 24451919:7 | [
{
"id": "291",
"type": "sentence",
"text": [
"Patients under each drug condition were compared with controls to assess normalization effects ."
],
"offsets": [
[
0,
96
]
]
}
] | [] | [] | [] | [] |
292 | 23849147:1 | [
{
"id": "293",
"type": "sentence",
"text": [
"We present a novel Bayesian adaptive comparative effectiveness trial comparing three treatments for status epilepticus that uses adaptive randomization with potential early stopping ."
],
"offsets": [
[
0,
183
]
]
}
] | [
{
"id": "294",
"type": "intervention",
"text": [
"Bayesian adaptive comparative effectiveness trial"
],
"offsets": [
[
19,
68
]
],
"normalized": []
},
{
"id": "295",
"type": "outcome",
"text": [
"effectiveness"
],
"offsets": [
[
49,
62
]
],
"normalized": []
},
{
"id": "296",
"type": "participant",
"text": [
"status epilepticus"
],
"offsets": [
[
100,
118
]
],
"normalized": []
}
] | [] | [] | [] |
297 | 12576806:15 | [
{
"id": "298",
"type": "sentence",
"text": [
"Two weeks seems to be a sufficient duration to allow functional restoration across the ureteropelvic junction after endopyelotomy and decrease stent related complications ."
],
"offsets": [
[
0,
172
]
]
}
] | [
{
"id": "299",
"type": "outcome",
"text": [
"duration"
],
"offsets": [
[
35,
43
]
],
"normalized": []
},
{
"id": "300",
"type": "outcome",
"text": [
"stent related complications"
],
"offsets": [
[
143,
170
]
],
"normalized": []
},
{
"id": "301",
"type": "participant",
"text": [
"endopyelotomy"
],
"offsets": [
[
116,
129
]
],
"normalized": []
}
] | [] | [] | [] |
302 | 17321989:2 | [
{
"id": "303",
"type": "sentence",
"text": [
"There were 4 cases with possible systemic fungal infection in the itraconazole group , and there were 8 possible and 3 probable cases in the fluconazole group ."
],
"offsets": [
[
0,
160
]
]
}
] | [
{
"id": "304",
"type": "intervention",
"text": [
"itraconazole"
],
"offsets": [
[
66,
78
]
],
"normalized": []
},
{
"id": "305",
"type": "intervention",
"text": [
"fluconazole"
],
"offsets": [
[
141,
152
]
],
"normalized": []
}
] | [] | [] | [] |
306 | 9816035:16 | [
{
"id": "307",
"type": "sentence",
"text": [
"Toxicity was primarily hematological and bimodal : 32 % had grade 3 or 4 leukopenia and 24 % had grade 3 or 4 thrombocytopenia ; 22 % had no leukopenia and 44 % had no thrombocytopenia ."
],
"offsets": [
[
0,
186
]
]
}
] | [
{
"id": "308",
"type": "outcome",
"text": [
"Toxicity"
],
"offsets": [
[
0,
8
]
],
"normalized": []
},
{
"id": "309",
"type": "outcome",
"text": [
"hematological"
],
"offsets": [
[
23,
36
]
],
"normalized": []
},
{
"id": "310",
"type": "outcome",
"text": [
"leukopenia"
],
"offsets": [
[
73,
83
]
],
"normalized": []
},
{
"id": "311",
"type": "outcome",
"text": [
"thrombocytopenia"
],
"offsets": [
[
110,
126
]
],
"normalized": []
},
{
"id": "312",
"type": "outcome",
"text": [
"leukopenia"
],
"offsets": [
[
73,
83
]
],
"normalized": []
},
{
"id": "313",
"type": "outcome",
"text": [
"thrombocytopenia"
],
"offsets": [
[
110,
126
]
],
"normalized": []
}
] | [] | [] | [] |
314 | 18845996:6 | [
{
"id": "315",
"type": "sentence",
"text": [
"Factors with a P value of < or =0.25 within a cycle were included in a generalized estimating equations regression model ."
],
"offsets": [
[
0,
122
]
]
}
] | [] | [] | [] | [] |
316 | 23103798:15 | [
{
"id": "317",
"type": "sentence",
"text": [
"However , deterioration in some responders with time suggests the need for maintenance protocols ."
],
"offsets": [
[
0,
98
]
]
}
] | [] | [] | [] | [] |
318 | 23417625:1 | [
{
"id": "319",
"type": "sentence",
"text": [
"High-functioning autism ( HFA ) is characterized by persistent impairment in social interaction despite the absence of mental retardation ."
],
"offsets": [
[
0,
139
]
]
}
] | [] | [] | [] | [] |
320 | 23417625:6 | [
{
"id": "321",
"type": "sentence",
"text": [
"The primary outcome was defined as an improvement of 2 points in error rates for facial emotion labeling ( DANVA2 ) from baseline ."
],
"offsets": [
[
0,
131
]
]
}
] | [
{
"id": "322",
"type": "outcome",
"text": [
"improvement of 2 points in error rates for facial emotion labeling ( DANVA2 ) from baseline"
],
"offsets": [
[
38,
129
]
],
"normalized": []
}
] | [] | [] | [] |
323 | 18337284:10 | [
{
"id": "324",
"type": "sentence",
"text": [
"The upper 95 % CL for the differences in positive cultures between the antibiotics was 4.9 % at days 3-6 , 6.5 % at days 12-16 and 8.5 % at days 26-36 ."
],
"offsets": [
[
0,
152
]
]
}
] | [
{
"id": "325",
"type": "outcome",
"text": [
"upper 95 % CL"
],
"offsets": [
[
4,
17
]
],
"normalized": []
}
] | [] | [] | [] |
326 | 21170734:2 | [
{
"id": "327",
"type": "sentence",
"text": [
"Blood samples were collected after these periods , when fish were immobile and reached stage 4 anesthesia ."
],
"offsets": [
[
0,
107
]
]
}
] | [
{
"id": "328",
"type": "outcome",
"text": [
"Blood samples"
],
"offsets": [
[
0,
13
]
],
"normalized": []
}
] | [] | [] | [] |
329 | 24803369:1 | [
{
"id": "330",
"type": "sentence",
"text": [
"Individuals with autism spectrum disorder ( ASD ) have difficulty comprehending metaphors ."
],
"offsets": [
[
0,
91
]
]
}
] | [
{
"id": "331",
"type": "intervention",
"text": [
"metaphors"
],
"offsets": [
[
80,
89
]
],
"normalized": []
},
{
"id": "332",
"type": "outcome",
"text": [
"comprehending metaphors"
],
"offsets": [
[
66,
89
]
],
"normalized": []
},
{
"id": "333",
"type": "participant",
"text": [
"Individuals with autism spectrum disorder ( ASD )"
],
"offsets": [
[
0,
49
]
],
"normalized": []
}
] | [] | [] | [] |
334 | 18845996:0 | [
{
"id": "335",
"type": "sentence",
"text": [
"Identifying patients at high risk for neutropenic complications during chemotherapy for metastatic breast cancer with doxorubicin or pegylated liposomal doxorubicin : the development of a prediction model ."
],
"offsets": [
[
0,
206
]
]
}
] | [
{
"id": "336",
"type": "intervention",
"text": [
"doxorubicin"
],
"offsets": [
[
118,
129
]
],
"normalized": []
},
{
"id": "337",
"type": "intervention",
"text": [
"pegylated liposomal doxorubicin"
],
"offsets": [
[
133,
164
]
],
"normalized": []
},
{
"id": "338",
"type": "outcome",
"text": [
"Identifying patients at high risk for neutropenic complications"
],
"offsets": [
[
0,
63
]
],
"normalized": []
},
{
"id": "339",
"type": "participant",
"text": [
"metastatic breast cancer"
],
"offsets": [
[
88,
112
]
],
"normalized": []
}
] | [] | [] | [] |
340 | 9816035:3 | [
{
"id": "341",
"type": "sentence",
"text": [
"The drug is extensively metabolized and detected in plasma and urine ."
],
"offsets": [
[
0,
70
]
]
}
] | [] | [] | [] | [] |
342 | 7831628:8 | [
{
"id": "343",
"type": "sentence",
"text": [
"Since the results were essentially identical between the techniques , it seems that comparable pathophysiological factors affect TLCO during breath holding and constant exhalation ."
],
"offsets": [
[
0,
181
]
]
}
] | [
{
"id": "344",
"type": "intervention",
"text": [
"TLCO"
],
"offsets": [
[
129,
133
]
],
"normalized": []
}
] | [] | [] | [] |
345 | 19802506:7 | [
{
"id": "346",
"type": "sentence",
"text": [
"Women who also exercised had additional increases in BMD at the femoral neck ( +0.29 % ) , total hip ( +0.34 % ) , spine ( +0.23 % ) , total radius ( +0.30 % ) , and additional decreases in Alkphase B ( -2.4 % ) and Serum NTx ( -6.5 % ) ."
],
"offsets": [
[
0,
238
]
]
}
] | [
{
"id": "347",
"type": "intervention",
"text": [
"exercised"
],
"offsets": [
[
15,
24
]
],
"normalized": []
},
{
"id": "348",
"type": "outcome",
"text": [
"BMD"
],
"offsets": [
[
53,
56
]
],
"normalized": []
},
{
"id": "349",
"type": "outcome",
"text": [
"Alkphase B"
],
"offsets": [
[
190,
200
]
],
"normalized": []
},
{
"id": "350",
"type": "outcome",
"text": [
"Serum NTx"
],
"offsets": [
[
216,
225
]
],
"normalized": []
}
] | [] | [] | [] |
351 | 10390665:0 | [
{
"id": "352",
"type": "sentence",
"text": [
"Anti-emetic efficacy of prophylactic granisetron compared with perphenazine for the prevention of post-operative vomiting in children ."
],
"offsets": [
[
0,
135
]
]
}
] | [
{
"id": "353",
"type": "intervention",
"text": [
"granisetron"
],
"offsets": [
[
37,
48
]
],
"normalized": []
},
{
"id": "354",
"type": "intervention",
"text": [
"perphenazine"
],
"offsets": [
[
63,
75
]
],
"normalized": []
},
{
"id": "355",
"type": "outcome",
"text": [
"Anti-emetic efficacy"
],
"offsets": [
[
0,
20
]
],
"normalized": []
},
{
"id": "356",
"type": "outcome",
"text": [
"prevention"
],
"offsets": [
[
84,
94
]
],
"normalized": []
},
{
"id": "357",
"type": "participant",
"text": [
"children"
],
"offsets": [
[
125,
133
]
],
"normalized": []
}
] | [] | [] | [] |
358 | 12960652:1 | [
{
"id": "359",
"type": "sentence",
"text": [
"Gastrointestinal symptoms have been reported in association with myoelectrical dysrhythmia , where different types of gastric electrical activity have been described ."
],
"offsets": [
[
0,
167
]
]
}
] | [
{
"id": "360",
"type": "outcome",
"text": [
"myoelectrical dysrhythmia"
],
"offsets": [
[
65,
90
]
],
"normalized": []
},
{
"id": "361",
"type": "outcome",
"text": [
"gastric electrical activity"
],
"offsets": [
[
118,
145
]
],
"normalized": []
}
] | [] | [] | [] |
362 | 9816035:15 | [
{
"id": "363",
"type": "sentence",
"text": [
"Escalation and reduction in dose was mandated dependent on hematotoxicity or lack thereof ."
],
"offsets": [
[
0,
91
]
]
}
] | [] | [] | [] | [] |
364 | 18845996:9 | [
{
"id": "365",
"type": "sentence",
"text": [
"A precycle risk score from > or =25 to < 40 for a given patient was identified as being the optimal threshold for sensitivity ( 58.0 % ) and specificity ( 78.7 % ) ."
],
"offsets": [
[
0,
165
]
]
}
] | [
{
"id": "366",
"type": "outcome",
"text": [
"precycle risk score"
],
"offsets": [
[
2,
21
]
],
"normalized": []
}
] | [] | [] | [] |
367 | 21106663:10 | [
{
"id": "368",
"type": "sentence",
"text": [
"These results are not concordant with the view that intentional smoking abstinence exacerbates depressive symptoms ."
],
"offsets": [
[
0,
116
]
]
}
] | [
{
"id": "369",
"type": "outcome",
"text": [
"depressive symptoms"
],
"offsets": [
[
95,
114
]
],
"normalized": []
}
] | [] | [] | [] |
370 | 23417625:4 | [
{
"id": "371",
"type": "sentence",
"text": [
"Eligible patients were children and adolescents with HFA ."
],
"offsets": [
[
0,
58
]
]
}
] | [
{
"id": "372",
"type": "participant",
"text": [
"Eligible patients were children and adolescents with HFA"
],
"offsets": [
[
0,
56
]
],
"normalized": []
}
] | [] | [] | [] |
373 | 12576806:6 | [
{
"id": "374",
"type": "sentence",
"text": [
"A symptom based questionnaire was administered to all patients at stent removal ."
],
"offsets": [
[
0,
81
]
]
}
] | [
{
"id": "375",
"type": "outcome",
"text": [
"symptom based questionnaire"
],
"offsets": [
[
2,
29
]
],
"normalized": []
}
] | [] | [] | [] |
376 | 20560622:7 | [
{
"id": "377",
"type": "sentence",
"text": [
"In accordance , calcium bioavailability in adolescents did not vary between the diets ( % WD = 40.4 +/- 5.1 , BD % = 38.2 +/- 3.6 ) ."
],
"offsets": [
[
0,
133
]
]
}
] | [
{
"id": "378",
"type": "outcome",
"text": [
"calcium bioavailability"
],
"offsets": [
[
16,
39
]
],
"normalized": []
}
] | [] | [] | [] |
379 | 16505427:10 | [
{
"id": "380",
"type": "sentence",
"text": [
"The Hb increment is somewhat greater with continued weekly epoetin alfa ."
],
"offsets": [
[
0,
73
]
]
}
] | [
{
"id": "381",
"type": "intervention",
"text": [
"epoetin alfa"
],
"offsets": [
[
59,
71
]
],
"normalized": []
},
{
"id": "382",
"type": "outcome",
"text": [
"Hb increment"
],
"offsets": [
[
4,
16
]
],
"normalized": []
}
] | [] | [] | [] |
383 | 7831628:0 | [
{
"id": "384",
"type": "sentence",
"text": [
"Measurement of transfer factor during constant exhalation ."
],
"offsets": [
[
0,
59
]
]
}
] | [] | [] | [] | [] |
385 | 12595499:5 | [
{
"id": "386",
"type": "sentence",
"text": [
"Inclusion criteria were known vascular disease or diabetes plus one other cardiovascular risk factor , exclusion criteria included heart failure or known impaired left ventricular function , dipstick-positive proteinuria ( > 1+ ) , and serum creatinine > 2.3 mg/dl ( 200 microM ) ."
],
"offsets": [
[
0,
281
]
]
}
] | [
{
"id": "387",
"type": "participant",
"text": [
"Inclusion criteria were known vascular disease or diabetes plus one other cardiovascular risk factor , exclusion criteria included heart failure or known impaired left ventricular function , dipstick-positive proteinuria ( > 1+ ) , and serum creatinine > 2.3 mg/dl ( 200 microM )"
],
"offsets": [
[
0,
279
]
],
"normalized": []
}
] | [] | [] | [] |
388 | 11737955:5 | [
{
"id": "389",
"type": "sentence",
"text": [
"Antipyrine reacts quickly with hydroxyl radicals to form para- and ortho-hydroxyantipyrine ."
],
"offsets": [
[
0,
92
]
]
}
] | [
{
"id": "390",
"type": "intervention",
"text": [
"Antipyrine"
],
"offsets": [
[
0,
10
]
],
"normalized": []
},
{
"id": "391",
"type": "outcome",
"text": [
"Antipyrine"
],
"offsets": [
[
0,
10
]
],
"normalized": []
},
{
"id": "392",
"type": "outcome",
"text": [
"para- and ortho-hydroxyantipyrine"
],
"offsets": [
[
57,
90
]
],
"normalized": []
}
] | [] | [] | [] |
393 | 11829043:7 | [
{
"id": "394",
"type": "sentence",
"text": [
"For the QoL-Colostomy , however , there was no significant difference between the control and experimental groups ."
],
"offsets": [
[
0,
115
]
]
}
] | [
{
"id": "395",
"type": "outcome",
"text": [
"QoL-Colostomy"
],
"offsets": [
[
8,
21
]
],
"normalized": []
}
] | [] | [] | [] |
396 | 18229990:0 | [
{
"id": "397",
"type": "sentence",
"text": [
"Language outcome in autism : randomized comparison of joint attention and play interventions ."
],
"offsets": [
[
0,
94
]
]
}
] | [
{
"id": "398",
"type": "intervention",
"text": [
"joint attention"
],
"offsets": [
[
54,
69
]
],
"normalized": []
},
{
"id": "399",
"type": "intervention",
"text": [
"play interventions"
],
"offsets": [
[
74,
92
]
],
"normalized": []
},
{
"id": "400",
"type": "outcome",
"text": [
"Language outcome"
],
"offsets": [
[
0,
16
]
],
"normalized": []
},
{
"id": "401",
"type": "participant",
"text": [
"autism"
],
"offsets": [
[
20,
26
]
],
"normalized": []
}
] | [] | [] | [] |
402 | 21106663:0 | [
{
"id": "403",
"type": "sentence",
"text": [
"Time-varying smoking abstinence predicts lower depressive symptoms following smoking cessation treatment ."
],
"offsets": [
[
0,
106
]
]
}
] | [
{
"id": "404",
"type": "outcome",
"text": [
"depressive symptoms"
],
"offsets": [
[
47,
66
]
],
"normalized": []
}
] | [] | [] | [] |
405 | 7831628:3 | [
{
"id": "406",
"type": "sentence",
"text": [
"Additionally , because prolonged breath holding is not required , measurements can readily be made in dyspnoeic patients ."
],
"offsets": [
[
0,
122
]
]
}
] | [
{
"id": "407",
"type": "participant",
"text": [
"dyspnoeic patients"
],
"offsets": [
[
102,
120
]
],
"normalized": []
}
] | [] | [] | [] |
End of preview. Expand
in Dataset Viewer.
Dataset Card for PICO Annotation
This dataset contains annotations for Participants, Interventions, and Outcomes (referred to as PICO task). For 423 sentences, annotations collected by 3 medical experts are available. To get the final annotations, we perform the majority voting.
Citation Information
@inproceedings{zlabinger-etal-2020-effective,
title = "Effective Crowd-Annotation of Participants, Interventions, and Outcomes in the Text of Clinical Trial Reports",
author = {Zlabinger, Markus and
Sabou, Marta and
Hofst{"a}tter, Sebastian and
Hanbury, Allan},
booktitle = "Findings of the Association for Computational Linguistics: EMNLP 2020",
month = nov,
year = "2020",
address = "Online",
publisher = "Association for Computational Linguistics",
url = "https://aclanthology.org/2020.findings-emnlp.274",
doi = "10.18653/v1/2020.findings-emnlp.274",
pages = "3064--3074",
}
- Downloads last month
- 66