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BigScience Biomedical Datasets 140

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(2010). They collected verbal estimates and free-hand measures of outdoor hills using the present device for a set of campus paths ranging from nearly flat (0.5°) to fairly steep (8.6°). Note that the perceived orientation of any specific outdoor hill may depend on a variety of factors in addition to its physical slant (e.g., curvature and viewing distance), but if the free-hand measure represents the NSE orientation, then we should expect the relationship between verbal estimates and free hand (NSE) estimates to remain similar to that observed for near surfaces. In other words, we should be able to make a prediction about the verbal estimates based on the free-hand estimates. ----- Figure 7 to be inserted here ----Figure 7 shows Stigliani et al.’s (2010) numeric estimation data for outdoor slopes plotted against the corresponding free-hand estimates (NSE) for each physical path (physical path inclination is shown next to each data point).

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Second, HASM cells in culture, when observed between 3 and 6 h after plating, were not spindle shaped or aligned in parallel, as they are at the tissue level (5); instead, they were irregularly shaped (Fig.

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These results are inconsistent with those of previous studies, which generally suggest that leptin is associated with sympathetic activation [11].

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polycystic lesions showing extensive growth in the extracerebral CSF spaces and secondary invagination of the brain [13].

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The 47 pixels whose NDVI values were greater than 0 and less than 0.2 were seen as non-vegetation pixels (Tsai et al., 2007; Noujdina and Ustin, 2008).

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) Botswana[102], Nigeria[87], South Africa[101], Zimbabwe[94] Comoro rousette (Rousettus oblivious) Comoros[107] House mouse (Mus musculus) Kenya[124], Madagascar[118] Pigs (Sus scrofa domesticus) South Africa[104, 122] Rusty-bellied brush-furred rat (Lophuromys sikapusi) Cameroon[109] L.

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Our algorithm extends the work [25] which addresses the traditional semi-supervised learning problem where labeled data is from a single source.

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Contrarily for the TRECVID 2010 dataset we have used linear SVM to learn from a suitable feature map (homogeneous kernel map) built by the histogram intersection kernel [137, 138].

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The application that motivated the calculation of g J was the identification of dot-depth one languages [49] according to a natural hierarchy of plus-free languages introduced by Brzozowski [29].

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To quantify habitat indication for each native and non-native species, we used an objective method that we developed in previous studies of effects of invasions, land management practices, or environmental conditions on plant species composition in a variety of ecosystems in MS (Brewer 2008; Brewer and Menzel 2009; Brewer 2011; Brewer et al. 2012).

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However, the reduction of GnRHR gene expression during inflammation in the PT may also result from the direct action of pro-inflammatory cytokines and stress, because both IL-1β and corticotropin-releasing hormone (CRH) were shown to suppress GnRHR expression [14,38,39].

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The vast majority of the Dot/Icm T4S effectors that gain access to the host cell cytoplasm are not absolutely required for bacterial intracellular replication, as the individual effector mutants do not replicate to lower numbers than WT bacteria (91).

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However, there are inevitably errors or uncertainties in spatial data, which are used to represent reality world (Goodchild and Gopal, 1989; Guptill and Morrison, 1995 Burrough and Frank, 1996; Shi and Liu, 2000).

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5 (Duarte et al., 2004; Hamada et al., 1999; Hrabe de Angelis et al., 1997; Xue et al., 1999).

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Candida spp. has been reported as one of the most common pathogens that cause hospital-acquired bloodstream infections in patients undergoing surgical or chemotherapeutic interventions and/or with underlying immunological deficiencies (Wisplinghoff et al., 2004; Pfaller & Diekema, 2007).

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By Perron’s theorem [27], the eigenvalue 1 is of multiplicity 1 and is the unique eigenvalue with maximum magnitude.

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This would also be consistent we our earlier study showing a threshold effect in electric field sensitivity, as evidenced by a sigmoidal dose–response curve (Kindzelskii and Petty 2000), which is a widelyrecognized feature of systems exhibiting cooperativity.

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Two possible interpretations of these observations are (a) the spontaneous hydrolysis of PMSF (James 1978) and/ or (b) the existence of spontaneous reactivation (Estévez and Vilanova 2009).

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NC is thought to be the result of growth dysregulation affecting the mesodermal portion of the pilosebaceous unit (2), leading to a follicle-based hamartoma with imperfect differentiation in the epithelial portion (4).

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Greater scapular upward rotation was demonstrated in rotator cuff dysfunction [14, 40, 41] and anterior glenohumeral joint tightness [13].

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Partial and total inbreeding coefficients were calculated with the ENDOG program (Gutierrez et al., 2003), that uses the algorithms described by Meuwissen et al. (1992) y Lacy et al. (1996).

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The thromboembolic complication was the first symptom of HIT preceding a subsequent platelet-count decrease in four patients [22, 25, 36].

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unstructured in HSPB6 and predicted to have similar properties in HSPB1 (18), that is essential for this preferred association.

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Cyclin D1 protein is overexpressed in more than 50% of human BCs [28] and has been frequently detected early in breast pre-neoplasias [29].

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The MEK inhibitor PD98059, prevented AR induced by LPC (de Lamirande and Gagnon, 2002) but not by A23187 and zona pellucida (du Plessis et al., 2002).

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GST-fusion proteins comprising the C-terminus of wild-type and mutant SERTs were used for pull-down experiments carried out with SEC24C and SEC24D.

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In all previous attempts [15, 30, 34, 8, 64, 43], the overlap problem is handled by partitioning the placement area and adding new constraints to the formulation to restrict the movement of the cells before solving another optimization problem.

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mutant embryos (Deng et al., 1994; Yamaguchi et al., 1994; Sun et al., 1999; Guo and Li, 2007).

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Metal concentrations were measured using an ELAN® 6000 ICP-MS (Perkin-Elmer, SCIEX, USA) (Maher et al. 2001).

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A recent storytelling task by Hendriks et al. (2014) confirmed this overall pattern but also highlighted that other factors can modulate this effect of the discourse stages.

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…did not use any chemical, biochemical or physiological characters, but in later taxomomic studies of Aspergillus physiological tests (Klich & Pitt 1988) and secondary metabolites (for example Frisvad 1989; Frisvad et al. 1998a, 2004; Samson et al. 2004; Frisvad et al. 2007) have been introduced.

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During the uplift of the Tibetan Plateau, river captures and flow reversals caused regional extension of the Yangtze River basin to the eastern Tibetan Plateau (Clark et al. 2004; Fan et al. 2005).

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Nowadays, there are only a few studies that have a systemic view on these accidents (Bentley 2008) and which try, by using detailed analysis (Gao and Abeysekera 2004, Leclercq and Thouy 2004, Bentley et al.

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The authors proposed that partial repairs would restore the force couple of the humeral head and increase acromion-humeral distance, resulting in dramatic changes in pain and function [16-19].

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Given that the angular spacings between adjacent views in golden angle acquisition are unevenly distributed, 610 views were used in the outermost region to fulfill the Nyquist criterion for a 240 240 image matrix (15).

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Insulin sensitivity was estimated by the insulin sensitivity index (SI) [6]; beta cell function was assessed as an index of the corrected insulinogenic response (CIR) [7] and disposition index (DI=CIR×SI) to adjust insulin secretion for SI.

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Neurotransmitter release at the NMJ is regulated by factors intrinsic to the motor neuron, including proteins that regulate intracellular signaling, as well as retrograde signals that convey postsynaptic activity levels to modulate neuronal properties (Collins and DiAntonio, 2007; Harris and Littleton, 2015; Menon et al., 2013).

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This indicates that GJIC is important for controlling the balance between proliferation and apoptosis of fibroblasts in the skin, as well as for managing the production of ECM [11].

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While many genetic correlations between body parts in Drosophila are positive (Cowley and Atchley 1990; Norry et al. 1997), an exception appears to exist for the eyes and head.

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HA monomer, consisting of two linked subunits; HA1 (~324 amino acids) and HA2 (~222 amino acids, (Webster et al., 1992), totally weighs about 60 kDa in the unglycosylated form (Sriwilaijaroen et al.

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Duschek and Schandry (2007) reported recently that impaired brain perfusion in hypotension especially in middle cerebral arteries (MCA) can cause cognitive deficits and even depression.

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Thus, the Patient Health Questionnaire-9 (PHQ-9) (Kroenke et al. 2001)—already administered to students seeking services at the clinic—was chosen as the screening instrument for the study.

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Wadge has proposed in [112] a fragment of higher-order Horn logic called “definitional programs” as a meta-programming language “based on Church’s Simple Theory of Types” [112], that is, the Simply Typed Lambda Calculus or λ→ [28, 6].

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[35] To document in-depth the effects that cognitive impairment has on women’s personal and professional lives.

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In particular, it has been noted that high levels of abdominal fat pose a particularly severe risk for progress to metabolic disease (12–18), whereas fat deposited subcutaneously is more benign (17,19) and may actually be protective (20).

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In a number of cases this resulted in a similar effect on transcription, namely activation of cryptic splice sites and exon skipping (Gardella et al, 1996; Posteraro et al, 1998; Terracina et al, 1998; Weil et al, 1988).

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…sample into two groups comparing those who displayed high levels of behavior problems as indexed by the Eyberg Problem or Intensity factor, using previously validated cut-off scores and mirroring the criteria applied during recruitment for the study (Burns and Patterson 2001; Dishion et al. 2008).

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Dominant and non-dominant breast categorisation was implemented by examining the magnitude of superioinferior breast displacement (the direction in which the greatest breast displacement occurred; Scurr et al., 2010) of each breast, within each participant, and assigning the breast with the greatest superioinferior displacement as the dominant breast and the least as the non-dominant breast.

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…River Capture There is overwhelming evidence that the Indus, Brahmaputra, and Ganges Rivers, existed as separate river systems soon after the original India-Asia collision (~55–45 Million Years (MY) ago) and even before large-scale elevation of the Himalayan mountains (Clift and Blusztajn 2005).

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Group II anti-cryptococcal mAbs have been shown to enhance the function of effector cells (29, 44, 55) which likely have a primary role in host defense (56).

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For the MEC study, data for the three SNPs presented in this study were extracted from the GWA scan data generated using Illumina 660W.

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…remove excess copper and is observed by clinical symptoms such as hepatic abnormalities, neurological defects, more commonly psychiatric/behavioral symptoms (Hedera 2017), and eventually liver failure which can cause death when untreated (Chesi et al. 2016; DiDonato et al. 2002; Yu et al. 2017c).

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Comparison of Ptf1a regulation in the CNS and pancreas These findings parallel those recently reported in the pancreas, where the 2.3 kb 5 element is also active (Masui et al., 2008).

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found that about 74 % had no regrets about treatment choice although about half reported difficulty and distress in making the decision [4].

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…turkey P450 1A and 3A orthologs with respect to AFB1 metabolism in liver microsomal and heterologously-expressed systems, which are, in fact closer to humans than those from either mice and rats (Rawal et al., 2010b; Gallagher et al., 1994, 1996; Ueng et al., 1995, 1997; Yip and Coulombe, 2006).

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functions as a molecular switch that both controls the duration of the NF-nB transcriptional response (20).

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On the whole, we had better results than Winslow and Brunt [31], perhaps because all the operations were performed by a single surgeon in our series.

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32 We note that our use of the term ‘blatant’ refers to the type (and not extent) of dehumanization perceptions (see also Kteily et al., 2015).

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Recent research has shown that features of interest in physiological signals such as electrocardiogram [5], [6] and photoplethysmogram [7] can be detected accurately from these sparse pulses.

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Inclusion criteria were having erosions detected by endoscopy at enrollment into this study or having a past history of RE, and having reflux symptoms at enrollment into this study, which could be evaluated using the 8-item Short-Form Health Survey (SF 8TM, Japanese translation) [12, 13] and the Frequency Scale for the Symptoms of GERD (FSSG) [14].

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In addition, they are in keeping with reports that Ser19 phosphorylation is low in swine carotid arteries relaxed with forskolin (Meeks et al. 2008) as well as in a-toxin permeabilized mouse tail arteries relaxed with urocortin and cAMP (Lubomirov et al. 2006).

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In the domain of supply chain, logistics, and operations management, the approach has been popularized by Holmström et al. (2009), leading to promising initial applications (e.g., Finne and Holmström, 2013; Schleper and Busse, 2013; Tanskanen et al., 2015).

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While quantitative changes in bacterial numbers in the soil surrounding the AMF are seldom reported, changes in bacterial composition may occur (Olsson et al., 1996; Andrade et al., 1997).

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Up to now, studies of brucine are mainly focused on reducing the central toxicity by transdermal administration and improving the efficacy through a novel drug carrier [3, 10].

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On the other hand, phospho-GSK-3β has recently received attention as a common mediator in protective mechanisms activated by different interventions, including IPC and ischemic postconditioning (IPost-C) [3,4,11,12].

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Given the tree and the MSA, the Rate4Site algorithm (16) is used to calculate positionspecific evolutionary rates under an empirical Bayesian methodology (17).

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It has previously been shown that members of the ADAM family of metalloproteinases are expressed in adult thymi [7,8,9,10,12,13] and that ADAM8 is expressed in fetal and adult thymi [12,13].

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For PLP-based features, we used mixtures of 128 for baseline, SWCE and Multi-peak and mixture of 64 Gaussians for the Thomson_1 and Thomson_2 systems.

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The invaded range of the species is well known (e.g. Brown et al. 2011), but the native range of the species in Asia has until now been poorly understood (Poutsma et al. 2008).

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Similar results were found in other restinga areas of the State of Rio de Janeiro, where Eugenia and Erythroxylum (Erythroxylaceae) were pointed out as super host plants (Maia, 2001; Oliveira and Maia, 2005).

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lingual phrase-based machine translation system with a reranking post-processing step8 (Wubben et al., 2012) and Hybrid, a model which first performs sentence splitting and deletion operations over discourse representation structures and then further simplifies sentences with PBMT-R (Narayan and Gardent, 2014).

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Sixteen other subjects took part in studies of lower intensity but more prolonged exercise comprising 45 min at 70% _ VO2peak then to fatigue at 90% _ VO2peak [3, 4].

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This was surprising since sLex bearing LGALS3BP has been shown to be involved in the rolling of the ZR-75-1 breast cancer cell line on endothelial cells (8).

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2002) or by enforcing constitutive expression of Dnmt1 in cells (Feltus et al. 2003) or of the CpG-specific bacterial DNA methyltransferase SssI in isolated nuclei (Fatemi et al.

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But from the experimental results in Wang et al. [2014], we find that R1MP outperforms these algorithms.

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qRT-PCR of androgen regulated genes (TMPRSS2, KLK3), and DNA repair genes (PRKDC, POLE2, FANCI), were carried out as described previously (4) using the following primer pairs: GAPDH (F: GGAGCGAGATCCCTCCAAAAT, R: GGCTGTTGTCATACTTCTCATGG); TMPRSS2 (F: TACTCTGGAAGTTCATGGGC R: GTCATCCACTATTCCTTGGCT); KLK3 (F: TGAACCAGAGGAGTTCTTGAC R: TGACGTGATACCTTGAAGCA); PRKDC (F: AGCTGGCTTGCGCCTATTT R: GGGCACACCACTTTAACAAGA); POLE2 (F: CTGCTCCGTGGTGAAGCTAT, R: ATTCCTGGACTGCTGCTTCC); FANCI (F: TTCTCACTGCTCTTTTCAGGGAT, R: GCCCTGTTTCCTTTAGCTGC).

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Here we analyse the sustainability of the initiative over a 32-month period of operations, using a modified version of a framework developed by Sarriot et al. (2004a).

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…independent real factor analysis (or noisy ICA), together with the corresponding criteria for the number of independent factors (Xu, 1998b, 2000, 2001a); as well as (e) several extensions of LMSER learning and the corresponding criteria for the number of hidden units (Xu, 1993, 1998b, 2000, 2001a).

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8 To validate the quality of our categorization, the next section discusses series of experiments that compare the performance of the vector space categorization approach with one of the top classifiers, Naïve-Bayes (Friedman et al., 1997).

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Critically, however, our reliability results converge with other investigations in the literature using a variety of methodologies (e.g., Brown et al. 2014; Enock et al. 2014; Schmukle 2005; Staugaard 2009).

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On the other hand, there were reports showing that chewing rate and eating behavior did not differ between people with high and normal BMI [64, 65].

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Modelled HO2 concentrations were generally found to agree with observations (Mao et al., 2009).

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Recent studies found that dynein which was involved in neuronal migration may play an important role in the function of BDNF (Tsai et al., 2007; Zhou et al., 2012).

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Twelve studies [3, 11, 15, 44, 50, 56, 60–62, 67, 69] reported incorporating some form of cultural adaptation salient to AAs including recruitment of only AA participants [60–62, 67], culturally specific diet and PA modifications [3, 11, 50, 56, 60, 61, 67], cultural sensitivity training for research staff [44, 56], employing AA case managers and interventionists [3, 11, 50, 60, 67], special attention to religion and spirituality [60, 62], AA community-focused field-trips to grocery stores, parks, and so forth [50], selection of study site in anAA community [67], and the formation of a minority implementation committee [56].

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, 1993), and the nuclear mitotic apparatus (NuMA) proteins (Lydersen and Pettijohn, 1980; Compton et al., 1992; Yang and Snyder, 1992).

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This protein was essential for the maintenance of the kDNA during cell division (12).

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Periodic boundary conditions were applied and electrostatic interactions were treated using the smooth particle mesh Ewald method [41] with a grid spacing of 1 Å.

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The same 24 color pictures of Barbary macaques used in Pascalis et al. (2005) were used in this experiment to create 12 pairings (6 easy and 6 hard pairings).

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To understand the relationship between exercise intensity and affective responses research has focused on quantifying pre- to during and pre- to post-exercise changes in affective responses at different exercise intensities [3-14].

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They have been identified as one of the major threats to the maintenance of biodiversity and ecosystem functioning (Ruiz et al., 1997; Mack et al., 2000).

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The Tsimane’ reported being healthy at the time of the study but, in the past, they might have suffered from otorhinolaryngological or other diseases impairing olfaction [19].

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…neighbor matrices, PCNM) as predictors in our analyses as these are suggested to produce inflated R2-statistics apparently due to over-fitting (i.e. selection of too many axes, which may overemphasise the spatial component in the data) even when forward selection is used (Gilbert & Bennett, 2010).

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Imaging studies showed reduced activation of visual cortices during vestibular stimulation (Brandt et al., 1998; Brandt, 1999; Bense et al., 2001), and this was hypothesized to be a cortical mechanism contributing to stabilize visual images during self-motion, along with brainstem reflexes (such as the vestibulo-ocular reflex).

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The joint distribution differs significantly from the earlier distribution, developed in Forest et al. (2002) and used in Webster et al. (2003), because the model simulations for the twentieth century used by Forest et al. (2006, 2008) include several additional forcings.

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Our recent characterization of spike frequency adaptation intrinsic to VSMN led us to hypothesize that the duration of phase 2 should be positively correlated with increasing phase 3 frequency (Krans and Chapple 2005).

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Total IgA fractions from all sera were purified as previously described [13] and used in experiments at a concentration of 1 μg/ml.

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For example, Kawato et al. (1990) suggested that movement trajectories can be projected using critical via-points through which the trajectory has to pass at a certain time, rather than in terms of the moment-by-moment dynamics of the implemented movement trajectory. Optimal trajectories can then be learnt by applying local optimising principles for getting from one via-point to the next. In this way, impoverished predictions can be used to monitor rich implementations. In the same way, language users might predict particularly crucial aspects of an utterance, but the aspects that they predict will depend on the circumstances. More generally, Meyer & Hagoort question the value of predicting one’s own utterance. They argue that prediction is useful when it is likely to differ from the actual event. This is the case when predicting another person’s behaviour or when the result of one’s action is uncertain (e.g., moving in a strong wind). But they argue that people are confident about their own speech. Meyer & Hagoort admit that they will tend to be less confident in dialogue, and we agree. But more important, we argue that the behaviour of the production implementer is not fully determined by the production command, because the complex processes involved in production are subject to internal (“neural”) noise or priming (i.e., influences that may not be a result of the production command). Assuming that these sources of noise do not necessarily affect forward modelling as well, predicted speech may differ from actual speech. In addition, prediction is useful even if the behaviour is fully predictable, because it allows the actor to plan future behaviour on the basis of the prediction. In fact, we made such a proposal in relation to the order of heavy and light phrases (see sect. 3.1, target article). Hartsuiker claims that our account incorrectly predicts an early competitor effect in Huettig and Hartsuiker (2010). His claim is based on the assumption that Response/Pickering & Garrod: An integrated theory of language production and comprehension

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These results are in agreement with those reported by Schmalz et al.(20), who did not observe any negative effect in the viability of fibroblastkeratinocyte cells cultured onto pure Pd during 24 h.

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Synaptic heterogeneity is not the only evidence for plasticity of several synaptic parameters: (1) Hebbian pairing of pre and postsynaptic neurons was shown to result in a selective increase in low frequency synaptic transmission (Markram and Tsodyks, 1996) which is due to a specific change in U (Tsodyks and Markram, 1997); (2) while presynaptic regulation of neurotransmitter release is typically considered as a mechanism to block or enhance transmission between neurons, this action rather serves to change the frequency dependence of transmission; (3) paired pulse experiments that demonstrated changes in paired pulse ratios rather demonstrated changes in frequency dependence; (4) we have recently found that an initial stage of LTDa is preceded by a selective loss of facilitation (LTDf) (A.

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This technique is also applied to chemoembolization of tumor-feeding extrahepatic collateral vessels that develop with an incidence of approximately 25% (5,7), and chemoembolization of these ves-