problem
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Using CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCN(C(=O)OC(C)(C)C)C4)no2)cc1C#N to produce CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNC4)no2)cc1C#N, the solvents is C1COCCO1 and CO, the agents is Cl
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Using CC1(C)CCSc2ccccc21 and CC(=O)Cl to produce CC(=O)c1ccc2c(c1)C(C)(C)CCS2, the solvents is S=C=S, the agents is [Al+3] and [Cl-]
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Using CSc1ncc(C(O)c2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1 to produce CSc1ncc(Cc2cn(S(=O)(=O)c3ccccc3)c3ncc(Cl)cc23)cn1, the solvents is O=C(O)C(F)(F)F and ClCCl, the agents is CC[SiH](CC)CC
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Using FC(F)(F)c1ccnc(Cl)n1 and Cc1nc(C#Cc2ccnc(Cl)c2)c[nH]1 to produce Cc1nc(C#Cc2ccnc(Cl)c2)cn1-c1nccc(C(F)(F)F)n1, the solvents is CN(C)C=O, the agents is O=C([O-])[O-] and [K+]
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Using Cc1cc(C2=NOC(c3cc(Cl)cc(C(F)(F)F)c3)(C(F)(F)F)C2)ccc1C(=O)O and O=C1CNCN1 to produce Cc1cc(C2=NOC(c3cc(Cl)cc(C(F)(F)F)c3)(C(F)(F)F)C2)ccc1C(=O)N1CNC(=O)C1, the solvents is CN(C)C=O and CCN(C(C)C)C(C)C, the agents is F[P-](F)(F)(F)(F)F and CN(C)C(On1nnc2cccnc21)=[N+](C)C and Cl
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Using O=CC(=O)O and NNc1ccc(C(F)(F)F)cc1 to produce O=C(O)C=NNc1ccc(C(F)(F)F)cc1, the solvents is O, the agents is Cl
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Using c1cnc(N2CC[N+]3(CCCC3)CC2)nc1 and O=C1CC2(CCCC2)CC(=O)N1 to produce O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ncccn2)CC1, the solvents is CN(C)C=O, the agents is [Br-] and O=C([O-])[O-] and [K+]
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Using C[S+](C)(C)=O and Cc1cccc(C=O)c1O to produce Cc1cccc2c1OCC2O, the solvents is C1CCOC1, the agents is [Cl-] and [Na+] and [H-]
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Using O=C(O)C(F)F and NC[C@H]1CN(c2ccc(I)c(F)c2)C(=O)O1 to produce O=C(NC[C@H]1CN(c2ccc(I)c(F)c2)C(=O)O1)C(F)F, the solvents is ClCCl and CCN(C(C)C)C(C)C, the agents is CCN=C=NCCCN(C)C
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Using CN(C)C=O and O=Cc1cncc(-c2cc3ccc(Cl)cc3[nH]2)c1 to produce Cn1c(-c2cncc(C=O)c2)cc2ccc(Cl)cc21, the solvents is O, the agents is [Na+] and [H-]
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Using CCCC[Sn](CCCC)(CCCC)c1ccccc1 and CCCOc1ccc2c(c1)C(c1ccc(OC)cc1OS(=O)(=O)C(F)(F)F)C(C(=O)OC)C2c1ccc2c(c1)OCO2 to produce CCCOc1ccc2c(c1)C(c1ccc(OC)cc1-c1ccccc1)C(C(=O)OC)C2c1ccc2c(c1)OCO2, the solvents is C1COCCO1 and CCOC(C)=O, the agents is [Cl-] and [Li+] and c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
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Using NNc1ccc(S(N)(=O)=O)cc1 and O=C1Nc2ccc3[nH]ncc3c2C1=O to produce NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc4[nH]ncc4c32)cc1, the solvents is CCOC(C)=O and O, the agents is Cl
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Using Nc1cnccn1 and CC(C)(C)C1=CC(=O)C=C(C(C)(C)C)C1=O to produce CC(C)(C)C1=CC(=Nc2cnccn2)C=C(C(C)(C)C)C1=O, the solvents is CC(Cl)Cl and c1ccncc1, the agents is [Al+3] and [Cl-]
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Using Nc1nc2ccc([N+](=O)[O-])cc2s1 to produce Nc1ccc2nc(N)sc2c1, the solvents is C1CCOC1, the agents is [Ni]
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Using CNOC and CC(C)(C)OC(=O)N1CCN(c2ncc(C(=O)O)cn2)CC1 to produce CON(C)C(=O)c1cnc(N2CCN(C(=O)OC(C)(C)C)CC2)nc1, the solvents is ClCCl and CCN(CC)CC, the agents is CCN=C=NCCCN(C)C and On1nnc2ccccc21
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Using [C-]#N and FC(F)(F)c1cc(Br)ccc1CBr to produce N#CCc1ccc(Br)cc1C(F)(F)F, the solvents is CCO and O, the agents is [K+]
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Using CCOC(=O)c1c[nH]nc1N and COc1ccc(CCl)cc1 to produce CCOC(=O)c1cn(Cc2ccc(OC)cc2)nc1N, the solvents is CC#N, the agents is O=C([O-])[O-] and [K+]
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Using COCOc1cc(OCOC)cc(C(=O)OC)c1 to produce COCOc1cc(CO)cc(OCOC)c1, the solvents is CCOCC, the agents is [Al+3] and [Li+] and [H-]
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Using CC(=O)OC(c1nc2nc(C)c3c(n2n1)CCC3)C1(Br)C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CS[C@@H]21 to produce Cc1nc2nc(/C=C3/C(=O)N4C(C(=O)O)=CS[C@H]34)nn2c2c1CCC2, the solvents is CC#N and C1CCOC1, the agents is O=P([O-])([O-])[O-] and [Pd]
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Using ON=Cc1ccc(C(F)(F)F)cc1 to produce NCc1ccc(C(F)(F)F)cc1, the solvents is CO, the agents is [H][H] and [Pd]
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Using CCOC(=O)CC(=O)C(F)(F)F and NNc1ccccc1 to produce Oc1cc(C(F)(F)F)nn1-c1ccccc1, the solvents is CO, the agents is C and Cl
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Using CC(C)N1CC2N(C(=O)C(NC(=O)OCc3ccccc3)CN2S(=O)(=O)c2ccc(Cl)cc2Cl)C(Cc2ccc(Cl)cc2)C1=O to produce CC(C)N1CC2N(C(=O)C(N)CN2S(=O)(=O)c2ccc(Cl)cc2Cl)C(Cc2ccc(Cl)cc2)C1=O, the solvents is CC#N and CO, the agents is C[Si](C)(C)I
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Using COC(=O)C[C@@H](O)C(=O)N1CCN(c2nc(-c3ccccc3O)nc3cc(C)ccc23)CC1 to produce Cc1ccc2c(N3CCN(C(=O)[C@H](O)CC(=O)O)CC3)nc(-c3ccccc3O)nc2c1, the solvents is O and C1CCOC1, the agents is [Li]O
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Using COc1ccc2cc([C@H](C)C(=O)O)ccc2c1 and O=C1c2ccccc2C(=O)N1O to produce COc1ccc2cc([C@H](C)C(=O)ON3C(=O)c4ccccc4C3=O)ccc2c1, the solvents is CN(C)C=O and ClCCl, the agents is CCN=C=NCCCN(C)C and Cl
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Using CC(C)(C)OC(=O)NC1CCN(C2CCOCC2)CC1 to produce NC1CCN(C2CCOCC2)CC1, the solvents is C1COCCO1 and CO, the agents is Cl
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Using CSSC and O=C(O)c1ccc(Cl)c(F)c1 to produce CSc1c(C(=O)O)ccc(Cl)c1F, the solvents is C1CCOC1, the agents is [Li]CCCC and Cl
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Using CCOC(=O)C(C(C)=O)C(C)(C)C(Cl)CC(Cl)(Cl)Cl to produce CCOC(=O)C1(C(C)=O)C(CC(Cl)(Cl)Cl)C1(C)C, the solvents is CCO, the agents is Cl and [OH-] and [Ba+2]
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Using NCCCC(=O)O and O=C(Cl)OCc1ccccc1 to produce O=C(O)CCCNC(=O)OCc1ccccc1, the solvents is O and CC(C)=O, the agents is [Na+] and O=C([O-])O
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Using OC1CCCc2cccnc21 to produce O=C1CCCc2cccnc21, the solvents is ClCCl, the agents is O=[Mn]=O
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Using CC(C)(C)[Si](C)(C)Cl and N#CCc1ccc(O)cc1 to produce CC(C)(C)[Si](C)(C)Oc1ccc(CC#N)cc1, the solvents is CN(C)C=O and CCOCC, the agents is c1c[nH]cn1
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Using O=C([O-])[O-] and O=C1CCc2cc(O)ccc2N1 to produce COc1ccc2c(c1)CCC(=O)N2, the solvents is CC#N, the agents is [K+]
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Using O=C(O)c1ccc(C(=O)O)cc1 to produce O=C([O-])c1ccc(C(=O)[O-])cc1, the solvents is CCO and c1ccccc1, the agents is CCCC[N+](CCCC)(CCCC)CCCC and [OH-]
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Using N#CCCCBr and Oc1cccc(CN2CCCCC2)c1 to produce N#CCCCOc1cccc(CN2CCCCC2)c1, the solvents is C1CCOC1, the agents is [Na+] and [H-]
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Using O=[N+]([O-])c1ccc2c(cnn2Cc2cccc(F)c2)c1 to produce Nc1ccc2c(cnn2Cc2cccc(F)c2)c1, the solvents is CO, the agents is [Pd]
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Using CC(C)(C)OC(=O)NC1CCN(CCO)CC1 to produce NC1CCN(CCO)CC1, the solvents is CCO, the agents is Cl
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Using C1COCCN1 and O=Cc1cc(Br)ccc1F to produce Fc1ccc(Br)cc1CN1CCOCC1, the solvents is CC(=O)O and ClCCCl, the agents is [Na+] and [Na] and O=C([O-])O
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Using CC(C)Cn1c(=O)n(C)c(=O)c2cc(C(O)c3cccc(F)c3)sc21 to produce CC(C)Cn1c(=O)n(C)c(=O)c2cc(Cc3cccc(F)c3)sc21, the solvents is O=C(O)C(F)(F)F, the agents is [Na+] and CC[SiH](CC)CC and [OH-]
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Using CCCCc1ncc(CO)n1Cc1ccccc1Cl to produce CCCCc1ncc(C=O)n1Cc1ccccc1Cl, the solvents is Cc1ccccc1, the agents is [Mn+4] and [O-2]
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Using ClC1CCOCC1 and CC(=O)C=CN(C)C to produce CC(=O)C=CC1CCOCC1, the solvents is C1CCOC1, the agents is II
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Using Brc1cccc(Br)n1 and COC(=O)CO to produce COC(=O)COc1cccc(Br)n1, the solvents is CN(C)C=O, the agents is [H-]
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Using CCCc1nc(C(C)(C)O)c(C(=O)OCC)[nH]1 to produce CCCc1nc(C(C)(C)O)c(C(=O)O)[nH]1, the solvents is O and CO, the agents is [Li+] and Cl and [OH-]
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Using NC1CN(S(=O)(=O)O)C1=O and O=C(Cl)Cc1ccccc1 to produce O=C(Cc1ccccc1)NC1CN(S(=O)(=O)[O-])C1=O, the solvents is O and C1CCOC1, the agents is O=P(O)(O)O and [Na+] and O=C([O-])O
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Using Clc1cncc(Cl)n1 and OCc1ccccc1 to produce Clc1cncc(OCc2ccccc2)n1, the solvents is CS(C)=O, the agents is CC(C)(C)[O-] and [K+]
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Using CC(C)(C)[Si](C)(C)Cl and Oc1ccc(Cl)cc1Cl to produce CC(C)(C)[Si](C)(C)Oc1ccc(Cl)cc1Cl, the solvents is O, the agents is c1c[nH]cn1
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Using O=C1C=C([N+](=O)[O-])C(=O)c2ccccc21 and O=C1C(Cl)=C(Cl)C(=O)c2ccccc21 to produce O=C1C(O)=C([N+](=O)[O-])C(=O)c2ccccc21, the solvents is O and CO, the agents is O=[N+]([O-])[O-] and [Na+]
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Using CC(C)[Si](Cl)(C(C)C)C(C)C and Oc1ccc(Br)cc1 to produce CC(C)[Si](Oc1ccc(Br)cc1)(C(C)C)C(C)C, the solvents is CN(C)C=O and O, the agents is c1c[nH]cn1
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Using C=CCBr and CC(C)(C)c1ccccc1O to produce C=CCOc1ccccc1C(C)(C)C, the solvents is CCOC(C)=O and CC(C)=O, the agents is O=C([O-])[O-] and [K+]
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Using CC(O)c1ccco1 and C1CCOC1 to produce Cc1occc(=O)c1O, the solvents is O, the agents is ClCl and BrBr
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Using COC(=O)c1nsc(Cl)c1Cl to produce OCc1nsc(Cl)c1Cl, the solvents is CCO, the agents is [Na+] and [BH4-]
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Using COc1cc(C[C@@H](CO)[C@H](CO)Cc2ccc(O)c(OC)c2)ccc1O to produce COc1cc(CC2COCC2Cc2ccc(O)c(OC)c2)ccc1O, the solvents is CC#N, the agents is c1ccc(P(c2ccccc2)c2ccccc2)cc1 and [Br-]
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Using Cc1cc([N+](=O)[O-])c(C)cc1Cl and CC(C)(C)c1cccc(O)c1 to produce Cc1cc([N+](=O)[O-])c(C)cc1Oc1cccc(C(C)(C)C)c1, the solvents is CN(C)C=O, the agents is O=C([O-])[O-] and [K+]
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Using C=O and CC(C)(C)c1ccccc1O to produce CC(C)(C)c1cccc(C=O)c1O, the solvents is CC#N and CCN(CC)CC, the agents is [Cl-] and Cl and [Mg+2]
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Using O=C(O)Cc1cccc(I)c1 to produce OCCc1cccc(I)c1, the solvents is C1CCOC1, the agents is [Cl-] and [NH4+] and B
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Using CN1CCN(c2ccc([N+](=O)[O-])c(N)c2F)CC1 to produce Nc1ccc(N2CCN(C3CCCC3)CC2)cc1N, the solvents is ClC(Cl)Cl, the agents is O=[Mn]=O
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Using O=C(NC1CCN(Cc2ccccc2)CC1)C(F)(F)F to produce O=C(NC1CCNCC1)C(F)(F)F, the solvents is CO, the agents is [Pd]
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Using O=C1O[C@H]([C@@H](O)CO)C(O)=C1O to produce O=C1O[C@H]([C@@H](O)CO)[C@H](O)[C@@H]1O, the solvents is O, the agents is [Pd]
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Using O=Cc1ccc(Cl)cc1 and NO to produce ON=Cc1ccc(Cl)cc1, the solvents is ClC(Cl)Cl, the agents is Cl
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Using COC(=O)c1ccc(OC(C)C)c(C#N)c1 to produce CC(C)Oc1ccc(C(=O)O)cc1C#N, the solvents is C1CCOC1, the agents is [K+] and [OH-]
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Using O=CCCl and Nc1cc(Cl)ccn1 to produce Clc1ccn2ccnc2c1, the solvents is O and CCO, the agents is [Na+] and O=C([O-])O
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Using CON(C)C(C)=O and Clc1nccs1 to produce CC(=O)c1cnc(Cl)s1, the solvents is C1CCOC1, the agents is [Li]CCCC
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Using Cc1ccc(C#N)cc1Cl and O=C1CCC(=O)N1Br to produce N#Cc1ccc(CBr)c(Cl)c1, the solvents is O and ClC(Cl)(Cl)Cl, the agents is CC(C)(C#N)N=NC(C)(C)C#N
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Using Oc1cc(Cl)nnc1Cl and Cc1cccc(C2CC2)c1O to produce Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O, the solvents is O=S1(=O)CCCC1 and CO, the agents is [K+] and Cl and [OH-]
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Using Cc1ccc(C#N)cc1Cl and O=C1CCC(=O)N1Br to produce N#Cc1ccc(CBr)c(Cl)c1, the solvents is ClC(Cl)(Cl)Cl, the agents is CC(C)(C#N)N=NC(C)(C)C#N
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Using Oc1cc(Cl)nnc1Cl and Cc1cccc(C2CC2)c1O to produce Cc1cccc(C2CC2)c1Oc1nnc(Cl)cc1O, the solvents is Clc1ccccc1Cl and CC(C)(C)O, the agents is [Cs+] and [OH-]
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Using O=C1CCC(c2ccccc2)(c2ccccc2)C2CN(Cc3ccccc3)CC12 to produce O=C1CCC(c2ccccc2)(c2ccccc2)C2CNCC12, the solvents is CO, the agents is C and Cl
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Using O=C1CCC(c2ccccc2)(c2ccccc2)C2CN(Cc3ccccc3)CC12 to produce O=C1CCC(c2ccccc2)(c2ccccc2)C2CNCC12, the solvents is CO, the agents is Cl
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Using BrBr and Nc1cccnc1F to produce Nc1ccc(Br)nc1F, the solvents is CC(=O)O, the agents is [Na+] and CC(=O)[O-] and [OH-]
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Using O=CC(Cl)(Cl)Cl and C=C(C)C to produce C=C(C)CC(O)C(Cl)(Cl)Cl, the solvents is O, the agents is [Al+3] and [Cl-]
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Using O=[N+]([O-])c1cccc2cnccc12 and NO to produce Nc1ccc([N+](=O)[O-])c2ccncc12, the solvents is CCO, the agents is [Na+] and Cl and [OH-]
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Using CN1CCCCC(C2=C(Cl)C(=O)CCC2)C1=O to produce CN1CCCCC(c2cccc(O)c2)C1=O, the solvents is CC(=O)O and O, the agents is Br
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Using O=C1CCCCC1 and Nc1c2ccccc2nn1-c1ccccc1 to produce c1ccc(-n2nc3ccccc3c2NC2CCCCC2)cc1, the solvents is CC(=O)O and ClCCl, the agents is CC(=O)O[BH-](OC(C)=O)OC(C)=O and [Na+]
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Using O=C(c1ccccc1)n1ccc2ccc(Br)nc21 to produce Brc1ccc2cc[nH]c2n1, the solvents is CO, the agents is [Na+] and [OH-]
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Using c1ccc2c(c1)sc1ccccc12 and CC(=O)Cl to produce CC(=O)c1ccc2sc3ccccc3c2c1, the solvents is S=C=S, the agents is [Al+3] and [Cl-]
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Using Cn1c(=O)[nH]c(=O)c2[nH]cnc21 and BrCc1ccccc1 to produce Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccccc1, the solvents is CCOC(C)=O and CN(C)C=O, the agents is O=C([O-])[O-] and [K+]
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Using C#CCCC(=O)OC and COc1cc[nH]c1/C=C1\C(=O)Nc2ccc([N+](=O)[O-])c(Br)c21 to produce COC(=O)CCC#Cc1c([N+](=O)[O-])ccc2c1/C(=C/c1[nH]ccc1OC)C(=O)N2, the solvents is CN(C)C=O and CCN(CC)CC, the agents is [Cu]I and Cl[Pd](Cl)([P](c1ccccc1)(c1ccccc1)c1ccccc1)[P](c1ccccc1)(c1ccccc1)c1ccccc1
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Using O=C(O)CCc1c[nH]cn1 and Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CNC1 to produce Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CN(C(=O)CCc2c[nH]cn2)C1, the solvents is CN(C)C=O and CCN(C(C)C)C(C)C, the agents is CCN=C=NCCCN(C)C and On1nnc2cccnc21 and Cl
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