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The earliest surviving valentine is a 15th-century rondeau written by Charles, Duke of Orléans to his wife, which commences.
Who wrote the oldest known rondeau?
2940eee13be94b9b4b2b9eaddbe95373f2974da1
en
Charles, Duke of Orléans
Dragon Ball Z (Japanese: ドラゴンボールZ (ゼット), Hepburn: Doragon Bōru Zetto, commonly abbreviated as DBZ) is a Japanese anime television series produced by Toei Animation. It is the sequel to the Dragon Ball anime and adapts the latter 325 chapters of the original 519-chapter Dragon Ball manga series created by Akira Toriyama which ran in Weekly Shōnen Jump from 1988-1995. Dragon Ball Z aired in Japan on Fuji TV from April 26, 1989 to January 31, 1996, before getting dubbed in territories including the United States, Canada, Australia, Europe, India, and Latin America. It was broadcast in at least 81 countries worldwide. It is part of the Dragon Ball media franchise.
who is the producer to Dragon Ball Z?
e2ccecce4aa7dcb4639bb71d8fd982449a95d9ec
en
Toei Animation
Muslims are commanded to perform prayers five times a day. These prayers are obligatory on every Muslim who has reached the age of puberty, with the exception being those who are mentally ill, too physically ill for it to be possible, menstruating, or experiencing postnatal bleeding. Those who are sick or otherwise physically unable to offer their prayers in the traditional form are permitted to offer their prayers while sitting or lying, as they are able.
how many times in one day are Muslims supposed to pray?
2160a67c1ebaee5e6bc466fa0880313f6272d23e
en
five times
Prayer in congregation (jama'ah) is considered to have more social and spiritual benefit than praying by oneself. When praying in congregation, the people stand in straight parallel rows behind one person who conduct the prayer, called imam, and face the qibla. The imam is usually chosen to be a scholar or the one who has the best knowledge of the Qur'an, preferably someone who has memorized it (a hafiz). In the first row behind the imam, if available, would be another hafiz to correct the imam in case a mistake is made during the performance of the salah. The prayer is performed as normal, with the congregation following the actions and movements of the imam as he performs the salah.
What is the name of the person who actually conducts the prayer?
b93eefb84e97d7a4829216a0cdf38f3c2ab1c9bc
en
imam
Born in Delhi, Sachdev was introduced to the game by her mother, Anju, at the age of 6. Her parents provided her with professional training. She achieved her first international title when she was eight. She was coached by K.C. Joshi during her early years. As a child, Tania Sachdev won multiple events. Her career successes are under-12 Indian champion, Asian U14 girls' champion in 2000 and bronze medalist at the 1998 World U12 Girls Championship. In 2002, she won the Asian Junior Girls Championship in Marawila.
Who gave Anju the training she needed
b9f90816cb3a39c306c37c151082e43081da9f54
en
Her parents
Born in Delhi, Sachdev was introduced to the game by her mother, Anju, at the age of 6. Her parents provided her with professional training. She achieved her first international title when she was eight. She was coached by K.C. Joshi during her early years. As a child, Tania Sachdev won multiple events. Her career successes are under-12 Indian champion, Asian U14 girls' champion in 2000 and bronze medalist at the 1998 World U12 Girls Championship. In 2002, she won the Asian Junior Girls Championship in Marawila.
When did she win the award?
d7927c29f2f8c07d1992e2a71b38d4683e9ad623
en
2002
Tania Sachdev (born 20 August 1986) is an Indian chess player, who holds the FIDE titles of International Master (IM) and Woman Grandmaster (WGM). She is also a chess presenter and commentator.
Who commentates and presents chess matches?
2049959ab824e092f0509c564a054eb5cf5abbd4
en
Tania Sachdev
Haplogroup L1 is a human mitochondrial DNA (mtDNA) haplogroup. It is most common in Central Africa and West Africa.
What does mtDNA stand for?
4a15d93808d9e94cd989ef272866fde441290eb7
en
mitochondrial DNA
Haplogroup L1 is believed to have appeared approximately 110,000 to 170,000 years ago. Haplogroup L1 is a daughter of L1-6 and genetic marker changes are 3666, 7055, 7389, 13789, 14178 and 14560.
when did Haplogroup L1 appear
653bd5235a6140069f2d714285c3bcf987bf9264
en
110,000 to 170,000 years ago
Nangarhār (Pashto: ننګرهار‎; Persian: ننگرهار‎), also called Nangrahar or Ningrahar, is one of the 34 provinces of Afghanistan, located in the eastern part of the country. It is divided into twenty-two districts and has a population of about 1,436,000. The city of Jalalabad is the capital of Nangarhar province.
Into how many districts is Nangrahar divided?
3d70bb32fcebd4922fed4d32faa5d8ae49bdf81c
en
twenty-two
Nangarhār (Pashto: ننګرهار‎; Persian: ننگرهار‎), also called Nangrahar or Ningrahar, is one of the 34 provinces of Afghanistan, located in the eastern part of the country. It is divided into twenty-two districts and has a population of about 1,436,000. The city of Jalalabad is the capital of Nangarhar province.
How many provinces are in Afghanistan?
fefdfa91dff45fe8536dbee041f3c4985fde8861
en
34
The national bird of Honduras is the scarlet macaw (Ara macao). This bird was much valued by the pre-Columbian civilizations of Honduras.
Early civilizations of the country of Honduras placed a high value on which bird?
96674311793cfa9235480fbe9d6eb9fd550bd1b3
en
scarlet macaw
The Embassy opened at its Jerusalem location on May 14, 2018, the 70th anniversary of the creation of the modern State of Israel. It was relocated from its previous site in Tel Aviv by the Donald Trump Administration and is situated in the Arnona section of the US Consulate. The opening prayer was delivered by the Evangelical Reverend Robert Jeffress, and the closing prayer was given by the Evangelical Reverend John C. Hagee.The move came 23 years after the passage of the Jerusalem Embassy Act of October 23, 1995, which set a deadline of May 31, 1999, for the move. The Clinton, Bush, and Obama administrations had all deferred the move. Eugene Kontorovich claimed that the decision to shift the US embassy to this area is tantamount to the United States recognizing Israeli sovereignty over land that it captured in the Six-Day War in 1967.However, despite the move of the Embassy to Jerusalem, President Trump signed on June 4, 2018 an executive order postponing the move of the Embassy to Jerusalem, although it already moved to that city. He was required to sign the order since the Jerusalem Embassy Act requires the US Ambassador to have a permanent residence in Jerusalem, a condition not yet fulfilled.
The Donald Trump Administration was responsible for the movement of the Israeli embassy to what location after years of waiting?
ea2d10719ed234cbef0cfa13e4b07fdeb5d4a6eb
en
Jerusalem
The Embassy opened at its Jerusalem location on May 14, 2018, the 70th anniversary of the creation of the modern State of Israel. It was relocated from its previous site in Tel Aviv by the Donald Trump Administration and is situated in the Arnona section of the US Consulate. The opening prayer was delivered by the Evangelical Reverend Robert Jeffress, and the closing prayer was given by the Evangelical Reverend John C. Hagee.The move came 23 years after the passage of the Jerusalem Embassy Act of October 23, 1995, which set a deadline of May 31, 1999, for the move. The Clinton, Bush, and Obama administrations had all deferred the move. Eugene Kontorovich claimed that the decision to shift the US embassy to this area is tantamount to the United States recognizing Israeli sovereignty over land that it captured in the Six-Day War in 1967.However, despite the move of the Embassy to Jerusalem, President Trump signed on June 4, 2018 an executive order postponing the move of the Embassy to Jerusalem, although it already moved to that city. He was required to sign the order since the Jerusalem Embassy Act requires the US Ambassador to have a permanent residence in Jerusalem, a condition not yet fulfilled.
Which presidential administrations deferred a move?
bda7746e9ea7bf7dfd4ad1f02099accebb9c789c
en
The Clinton, Bush, and Obama
Engels developed what is now known as Marxist theory together with Karl Marx and in 1845 he published The Condition of the Working Class in England, based on personal observations and research in English cities. In 1848, Engels co-authored The Communist Manifesto with Marx and also authored and co-authored (primarily with Marx) many other works. Later, Engels supported Marx financially, allowing him to do research and write Das Kapital. After Marx's death, Engels edited the second and third volumes of Das Kapital. Additionally, Engels organised Marx's notes on the Theories of Surplus Value, which he later published as the "fourth volume" of Capital. In 1884, he published The Origin of the Family, Private Property and the State on the basis of Marx's ethnographic research.
Who is known to have edited two additional volumes of Das Kapital following the death of Marx?
d45954ac9f664244a6e9ab426a7c6015d7653112
en
Engels
Fredrich Engels died of throat cancer in London on 5 August 1895, at the age of 74. Following cremation at Woking Crematorium, his ashes were scattered off Beachy Head, near Eastbourne as he had requested.
What type of cancer did Fredrich Engels have?
01d27483cf18a2f59627249dc3a26ac5d75af73e
en
throat
Ponomaryova later worked in orbital mechanics at the Gagarin Training Center. Following this, she was a research scientist at the Institute of Natural Historic Sciences. She was awarded a Candidate of Technical Sciences degree in 1974.
What year did she receive the accolade?
87c4a42ac9092953949d32652735b46a6d60cac7
en
1974
Ponomaryova later worked in orbital mechanics at the Gagarin Training Center. Following this, she was a research scientist at the Institute of Natural Historic Sciences. She was awarded a Candidate of Technical Sciences degree in 1974.
Where did Ponomaryova work after the Gagarin Training Center?
9f5c2d98d32b780ba5e14fc2c984be9cebf7e60c
en
Institute of Natural Historic Sciences
Ponomaryova later worked in orbital mechanics at the Gagarin Training Center. Following this, she was a research scientist at the Institute of Natural Historic Sciences. She was awarded a Candidate of Technical Sciences degree in 1974.
Who previously worked at the Institute of Natural Historic Sciences?
0a23aacbaf54c5efaee798ae1016949f16ad7243
en
Ponomaryova
Valentina Leonidovna Ponomaryova (Russian: Валентина Леонидовна Пономарёва, born 18 September 1933) is a former Soviet cosmonaut, pilot and scientist.
what was one of Valentina's profession?
5fa075b3f17eee0c9d35d211b0c0da5c15411e97
en
scientist
A statue of Isaac Newton, looking at an apple at his feet, can be seen at the Oxford University Museum of Natural History. A large bronze statue, Newton, after William Blake, by Eduardo Paolozzi, dated 1995 and inspired by Blake's etching, dominates the piazza of the British Library in London.
Where is the statue located?
1775af57a1421f6a2f7556f17bcef4ddc9c20ac8
en
Oxford University Museum of Natural History
Although born into an Anglican family, by his thirties Newton held a Christian faith that, had it been made public, would not have been considered orthodox by mainstream Christianity; in recent times he has been described as a heretic.By 1672 he had started to record his theological researches in notebooks which he showed to no one and which have only recently been examined. They demonstrate an extensive knowledge of early church writings and show that in the conflict between Athanasius and Arius which defined the Creed, he took the side of Arius, the loser, who rejected the conventional view of the Trinity. Newton "recognized Christ as a divine mediator between God and man, who was subordinate to the Father who created him." He was especially interested in prophecy, but for him, "the great apostasy was trinitarianism."Newton tried unsuccessfully to obtain one of the two fellowships that exempted the holder from the ordination requirement. At the last moment in 1675 he received a dispensation from the government that excused him and all future holders of the Lucasian chair.In Newton's eyes, worshipping Christ as God was idolatry, to him the fundamental sin. Historian Stephen D. Snobelen says, "Isaac Newton was a heretic. But ... he never made a public declaration of his private faith—which the orthodox would have deemed extremely radical. He hid his faith so well that scholars are still unravelling his personal beliefs." Snobelen concludes that Newton was at least a Socinian sympathiser (he owned and had thoroughly read at least eight Socinian books), possibly an Arian and almost certainly an anti-trinitarian.In a minority position, T.C. Pfizenmaier offers a more nuanced view, arguing that Newton held closer to the Semi-Arian view of the Trinity that Jesus Christ was of a "similar substance" (homoiousios) from the Father rather than the orthodox view that Jesus Christ is of the "same substance" of the Father (homoousios) as endorsed by modern Eastern Orthodox, Roman Catholics and Protestants. However, this type of view 'has lost support of late with the availability of Newton's theological papers', and now most scholars identify Newton as an Antitrinitarian monotheist.Although the laws of motion and universal gravitation became Newton's best-known discoveries, he warned against using them to view the Universe as a mere machine, as if akin to a great clock. He said, "Gravity explains the motions of the planets, but it cannot explain who set the planets in motion. God governs all things and knows all that is or can be done."Along with his scientific fame, Newton's studies of the Bible and of the early Church Fathers were also noteworthy. Newton wrote works on textual criticism, most notably An Historical Account of Two Notable Corruptions of Scripture and Observations upon the Prophecies of Daniel, and the Apocalypse of St. John. He placed the crucifixion of Jesus Christ at 3 April, AD 33, which agrees with one traditionally accepted date.He believed in a rationally immanent world, but he rejected the hylozoism implicit in Leibniz and Baruch Spinoza. The ordered and dynamically informed Universe could be understood, and must be understood, by an active reason. In his correspondence, Newton claimed that in writing the Principia "I had an eye upon such Principles as might work with considering men for the belief of a Deity". He saw evidence of design in the system of the world: "Such a wonderful uniformity in the planetary system must be allowed the effect of choice". But Newton insisted that divine intervention would eventually be required to reform the system, due to the slow growth of instabilities. For this, Leibniz lampooned him: "God Almighty wants to wind up his watch from time to time: otherwise it would cease to move. He had not, it seems, sufficient foresight to make it a perpetual motion."Newton's position was vigorously defended by his follower Samuel Clarke in a famous correspondence. A century later, Pierre-Simon Laplace's work "Celestial Mechanics" had a natural explanation for why the planet orbits do not require periodic divine intervention.
What did Snobelen think of Newton?
8f176f07aa24a8264860239ebbbe066dc9abf7e0
en
was a heretic
From 1670 to 1672, Newton lectured on optics. During this period he investigated the refraction of light, demonstrating that the multicoloured spectrum produced by a prism could be recomposed into white light by a lens and a second prism. Modern scholarship has revealed that Newton's analysis and resynthesis of white light owes a debt to corpuscular alchemy.He showed that coloured light does not change its properties by separating out a coloured beam and shining it on various objects, and that regardless of whether reflected, scattered, or transmitted, the light remains the same colour. Thus, he observed that colour is the result of objects interacting with already-coloured light rather than objects generating the colour themselves. This is known as Newton's theory of colour.
Where does colour come from?
8deebf03088b2efe6a248acb57439844faaf582b
en
objects interacting with already-coloured light
From 1670 to 1672, Newton lectured on optics. During this period he investigated the refraction of light, demonstrating that the multicoloured spectrum produced by a prism could be recomposed into white light by a lens and a second prism. Modern scholarship has revealed that Newton's analysis and resynthesis of white light owes a debt to corpuscular alchemy.He showed that coloured light does not change its properties by separating out a coloured beam and shining it on various objects, and that regardless of whether reflected, scattered, or transmitted, the light remains the same colour. Thus, he observed that colour is the result of objects interacting with already-coloured light rather than objects generating the colour themselves. This is known as Newton's theory of colour.
Who analyzed white light?
1412334a2b268481e33030d187013df11fe87fab
en
Newton
From 1978 until 1988, an image of Newton designed by Harry Ecclestone appeared on Series D £1 banknotes issued by the Bank of England (the last £1 notes to be issued by the Bank of England). Newton was shown on the reverse of the notes holding a book and accompanied by a telescope, a prism and a map of the Solar System.
Who designed the image of Newton on the one pound note in 1978?
8644cd93a1e1ca67c69db4c9e49ee261cae18905
en
Harry Ecclestone
He was appointed Lucasian Professor of Mathematics in 1669, on Barrow's recommendation. During that time, any Fellow of a college at Cambridge or Oxford was required to take holy orders and become an ordained Anglican priest. However, the terms of the Lucasian professorship required that the holder not be active in the church – presumably so as to have more time for science. Newton argued that this should exempt him from the ordination requirement, and Charles II, whose permission was needed, accepted this argument. Thus a conflict between Newton's religious views and Anglican orthodoxy was averted.
What colleges were ordered to take holy orders?
be840d83f09c9c98da4488aafda24eff3a055460
en
Cambridge or Oxford
Isaac Newton was born (according to the Julian calendar, in use in England at the time) on Christmas Day, 25 December 1642 (NS 4 January 1643) "an hour or two after midnight", at Woolsthorpe Manor in Woolsthorpe-by-Colsterworth, a hamlet in the county of Lincolnshire. His father, also named Isaac Newton, had died three months before. Born prematurely, Newton was a small child; his mother Hannah Ayscough reportedly said that he could have fit inside a quart mug. When Newton was three, his mother remarried and went to live with her new husband, the Reverend Barnabas Smith, leaving her son in the care of his maternal grandmother, Margery Ayscough. Newton disliked his stepfather and maintained some enmity towards his mother for marrying him, as revealed by this entry in a list of sins committed up to the age of 19: "Threatening my father and mother Smith to burn them and the house over them." Newton's mother had three children from her second marriage.From the age of about twelve until he was seventeen, Newton was educated at The King's School, Grantham, which taught Latin and Greek and probably imparted a significant foundation of mathematics. He was removed from school, and returned to Woolsthorpe-by-Colsterworth by October 1659. His mother, widowed for the second time, attempted to make him a farmer, an occupation he hated. Henry Stokes, master at The King's School, persuaded his mother to send him back to school. Motivated partly by a desire for revenge against a schoolyard bully, he became the top-ranked student, distinguishing himself mainly by building sundials and models of windmills.In June 1661, he was admitted to Trinity College, Cambridge, on the recommendation of his uncle Rev William Ayscough, who had studied there. He started as a subsizar—paying his way by performing valet's duties—until he was awarded a scholarship in 1664, guaranteeing him four more years until he could get his MA. At that time, the college's teachings were based on those of Aristotle, whom Newton supplemented with modern philosophers such as Descartes, and astronomers such as Galileo and Thomas Street, through whom he learned of Kepler's work. He set down in his notebook a series of "Quaestiones" about mechanical philosophy as he found it. In 1665, he discovered the generalised binomial theorem and began to develop a mathematical theory that later became calculus. Soon after Newton had obtained his BA degree in August 1665, the university temporarily closed as a precaution against the Great Plague. Although he had been undistinguished as a Cambridge student, Newton's private studies at his home in Woolsthorpe over the subsequent two years saw the development of his theories on calculus, optics, and the law of gravitation.
What did Henry Stokes do after being removed from school and returned to Woolsthorpe-by-Colsterworth?
dcc42ec6b396191626e80999aa237337761b5117
en
persuaded his mother to send him back to school
Isaac Newton was born (according to the Julian calendar, in use in England at the time) on Christmas Day, 25 December 1642 (NS 4 January 1643) "an hour or two after midnight", at Woolsthorpe Manor in Woolsthorpe-by-Colsterworth, a hamlet in the county of Lincolnshire. His father, also named Isaac Newton, had died three months before. Born prematurely, Newton was a small child; his mother Hannah Ayscough reportedly said that he could have fit inside a quart mug. When Newton was three, his mother remarried and went to live with her new husband, the Reverend Barnabas Smith, leaving her son in the care of his maternal grandmother, Margery Ayscough. Newton disliked his stepfather and maintained some enmity towards his mother for marrying him, as revealed by this entry in a list of sins committed up to the age of 19: "Threatening my father and mother Smith to burn them and the house over them." Newton's mother had three children from her second marriage.From the age of about twelve until he was seventeen, Newton was educated at The King's School, Grantham, which taught Latin and Greek and probably imparted a significant foundation of mathematics. He was removed from school, and returned to Woolsthorpe-by-Colsterworth by October 1659. His mother, widowed for the second time, attempted to make him a farmer, an occupation he hated. Henry Stokes, master at The King's School, persuaded his mother to send him back to school. Motivated partly by a desire for revenge against a schoolyard bully, he became the top-ranked student, distinguishing himself mainly by building sundials and models of windmills.In June 1661, he was admitted to Trinity College, Cambridge, on the recommendation of his uncle Rev William Ayscough, who had studied there. He started as a subsizar—paying his way by performing valet's duties—until he was awarded a scholarship in 1664, guaranteeing him four more years until he could get his MA. At that time, the college's teachings were based on those of Aristotle, whom Newton supplemented with modern philosophers such as Descartes, and astronomers such as Galileo and Thomas Street, through whom he learned of Kepler's work. He set down in his notebook a series of "Quaestiones" about mechanical philosophy as he found it. In 1665, he discovered the generalised binomial theorem and began to develop a mathematical theory that later became calculus. Soon after Newton had obtained his BA degree in August 1665, the university temporarily closed as a precaution against the Great Plague. Although he had been undistinguished as a Cambridge student, Newton's private studies at his home in Woolsthorpe over the subsequent two years saw the development of his theories on calculus, optics, and the law of gravitation.
who raised Isaac Newton?
33852d3f97b7651a7acc25675298ddcd3546fb3a
en
his maternal grandmother, Margery Ayscough
Isaac Newton was born (according to the Julian calendar, in use in England at the time) on Christmas Day, 25 December 1642 (NS 4 January 1643) "an hour or two after midnight", at Woolsthorpe Manor in Woolsthorpe-by-Colsterworth, a hamlet in the county of Lincolnshire. His father, also named Isaac Newton, had died three months before. Born prematurely, Newton was a small child; his mother Hannah Ayscough reportedly said that he could have fit inside a quart mug. When Newton was three, his mother remarried and went to live with her new husband, the Reverend Barnabas Smith, leaving her son in the care of his maternal grandmother, Margery Ayscough. Newton disliked his stepfather and maintained some enmity towards his mother for marrying him, as revealed by this entry in a list of sins committed up to the age of 19: "Threatening my father and mother Smith to burn them and the house over them." Newton's mother had three children from her second marriage.From the age of about twelve until he was seventeen, Newton was educated at The King's School, Grantham, which taught Latin and Greek and probably imparted a significant foundation of mathematics. He was removed from school, and returned to Woolsthorpe-by-Colsterworth by October 1659. His mother, widowed for the second time, attempted to make him a farmer, an occupation he hated. Henry Stokes, master at The King's School, persuaded his mother to send him back to school. Motivated partly by a desire for revenge against a schoolyard bully, he became the top-ranked student, distinguishing himself mainly by building sundials and models of windmills.In June 1661, he was admitted to Trinity College, Cambridge, on the recommendation of his uncle Rev William Ayscough, who had studied there. He started as a subsizar—paying his way by performing valet's duties—until he was awarded a scholarship in 1664, guaranteeing him four more years until he could get his MA. At that time, the college's teachings were based on those of Aristotle, whom Newton supplemented with modern philosophers such as Descartes, and astronomers such as Galileo and Thomas Street, through whom he learned of Kepler's work. He set down in his notebook a series of "Quaestiones" about mechanical philosophy as he found it. In 1665, he discovered the generalised binomial theorem and began to develop a mathematical theory that later became calculus. Soon after Newton had obtained his BA degree in August 1665, the university temporarily closed as a precaution against the Great Plague. Although he had been undistinguished as a Cambridge student, Newton's private studies at his home in Woolsthorpe over the subsequent two years saw the development of his theories on calculus, optics, and the law of gravitation.
In what year did he discover the generalized binomial theorem?
6eaf6cdc35490b6d82078a735319b29378171d08
en
1665
It is known from his notebooks that Newton was grappling in the late 1660s with the idea that terrestrial gravity extends, in an inverse-square proportion, to the Moon; however it took him two decades to develop the full-fledged theory. The question was not whether gravity existed, but whether it extended so far from Earth that it could also be the force holding the Moon to its orbit. Newton showed that if the force decreased as the inverse square of the distance, one could indeed calculate the Moon's orbital period, and get good agreement. He guessed the same force was responsible for other orbital motions, and hence named it "universal gravitation".
what was questioned about gravity?
7cb8a08435da80688b76e574ddd03f86c587dee2
en
whether it extended so far from Earth that it could also be the force holding the Moon to its orbit
It is known from his notebooks that Newton was grappling in the late 1660s with the idea that terrestrial gravity extends, in an inverse-square proportion, to the Moon; however it took him two decades to develop the full-fledged theory. The question was not whether gravity existed, but whether it extended so far from Earth that it could also be the force holding the Moon to its orbit. Newton showed that if the force decreased as the inverse square of the distance, one could indeed calculate the Moon's orbital period, and get good agreement. He guessed the same force was responsible for other orbital motions, and hence named it "universal gravitation".
What is Newton's idea of terrestrial gravity?
0d9d240495c4103e48aa59a4dc7d8ae384d64f80
en
if the force decreased as the inverse square of the distance, one could indeed calculate the Moon's orbital period
John Conduitt, Newton's assistant at the Royal Mint and husband of Newton's niece, also described the event when he wrote about Newton's life:
Who was Conduitt married to?
cfbf0f7b7044622d4cf9b5b58fff2f4adb2a6419
en
Newton's niece
Newton built the first practical reflecting telescope and developed a sophisticated theory of colour based on the observation that a prism separates white light into the colours of the visible spectrum. His work on light was collected in his highly influential book Opticks, published in 1704. He also formulated an empirical law of cooling, made the first theoretical calculation of the speed of sound, and introduced the notion of a Newtonian fluid. In addition to his work on calculus, as a mathematician Newton contributed to the study of power series, generalised the binomial theorem to non-integer exponents, developed a method for approximating the roots of a function, and classified most of the cubic plane curves.
Who was responsible for the observations in the spectrum?
f6d0c42792c166772d6947b1ae69a88ff0ae03da
en
Newton
Newton died in his sleep in London on 20 March 1727 (OS 20 March 1726; NS 31 March 1727). His body was buried in Westminster Abbey. Voltaire may have been present at his funeral. A bachelor, he had divested much of his estate to relatives during his last years, and died intestate. His papers went to John Conduitt and Catherine Barton. After his death, Newton's hair was examined and found to contain mercury, probably resulting from his alchemical pursuits. Mercury poisoning could explain Newton's eccentricity in late life.
What kind of poisoning helped explain Newton's later life?
3e7f0fd26153a784adf6aa6765a61f35d3d2fed5
en
Mercury
Newton died in his sleep in London on 20 March 1727 (OS 20 March 1726; NS 31 March 1727). His body was buried in Westminster Abbey. Voltaire may have been present at his funeral. A bachelor, he had divested much of his estate to relatives during his last years, and died intestate. His papers went to John Conduitt and Catherine Barton. After his death, Newton's hair was examined and found to contain mercury, probably resulting from his alchemical pursuits. Mercury poisoning could explain Newton's eccentricity in late life.
How did Newton die?
99eaecf7bcc8585dcefa55c1176bc896fc9a09b2
en
in his sleep
Newton was relatively modest about his achievements, writing in a letter to Robert Hooke in February 1676:
What type of communication occurred between these two men?
a05046cdf2cfbf0f5e3ee7cb0ad9f3125186886b
en
writing in a letter
Newton's work has been said "to distinctly advance every branch of mathematics then studied." His work on the subject usually referred to as fluxions or calculus, seen in a manuscript of October 1666, is now published among Newton's mathematical papers. The author of the manuscript De analysi per aequationes numero terminorum infinitas, sent by Isaac Barrow to John Collins in June 1669, was identified by Barrow in a letter sent to Collins in August of that year as "[...] of an extraordinary genius and proficiency in these things."Newton later became involved in a dispute with Leibniz over priority in the development of calculus (the Leibniz–Newton calculus controversy). Most modern historians believe that Newton and Leibniz developed calculus independently, although with very different mathematical notations. Occasionally it has been suggested that Newton published almost nothing about it until 1693, and did not give a full account until 1704, while Leibniz began publishing a full account of his methods in 1684. Leibniz's notation and "differential Method", nowadays recognised as much more convenient notations, were adopted by continental European mathematicians, and after 1820 or so, also by British mathematicians.Such a suggestion fails to account for the calculus in Book 1 of Newton's Principia itself and in its forerunner manuscripts, such as De motu corporum in gyrum of 1684; this content has been pointed out by critics of both Newton's time and modern times.His work extensively uses calculus in geometric form based on limiting values of the ratios of vanishingly small quantities: in the Principia itself, Newton gave demonstration of this under the name of "the method of first and last ratios" and explained why he put his expositions in this form, remarking also that "hereby the same thing is performed as by the method of indivisibles."Because of this, the Principia has been called "a book dense with the theory and application of the infinitesimal calculus" in modern times and in Newton's time "nearly all of it is of this calculus." His use of methods involving "one or more orders of the infinitesimally small" is present in his De motu corporum in gyrum of 1684 and in his papers on motion "during the two decades preceding 1684".
Which people are thought to have created the mathematical area known as calculus?
f56e644b8266381ada22b2c0a01faa2bdc94a072
en
Newton and Leibniz
Of Natures Obvious Laws & Processes in Vegetation (unpublished, c. 1671–75)
What was the year range?
21fec539768f1e537f1cef78d62d12020cda4543
en
1671–75
In the late nineteenth century, the neurophysiologist Vladimir Bekhterev of Russia in 1893, Adolph Strümpell of Germany in 1897, and Pierre Marie of France in 1898 were the first to give adequate descriptions which permitted an accurate diagnosis of AS prior to severe spinal deformity. For this reason, AS is also known as Bekhterev Disease, Bechterew's Disease or Marie–Strümpell Disease.
What medical condition were they trying to provide accurate descriptions of?
ce775ccadc5214d8ed1e3297d7831105dc16eed7
en
AS
It is not essential to use the standard Web forms development model when developing with ASP.NET. Noteworthy frameworks designed for the platform include:
What is one characteristic of developing with ASP.NET?
122617435ab89737ef43b74b702987bb01eff84f
en
not essential to use the standard Web forms development model
New York had been inhabited by tribes of Algonquian and Iroquoian-speaking Native Americans for several hundred years by the time the earliest Europeans came to New York. French colonists and Jesuit missionaries arrived southward from Montreal for trade and proselytizing. In 1609, the region was visited by Henry Hudson sailing for the Dutch East India Company. The Dutch built Fort Nassau in 1614 at the confluence of the Hudson and Mohawk rivers, where the present-day capital of Albany later developed. The Dutch soon also settled New Amsterdam and parts of the Hudson Valley, establishing the multicultural colony of New Netherland, a center of trade and immigration. England seized the colony from the Dutch in 1664. During the American Revolutionary War (1775–1783), a group of colonists of the Province of New York attempted to take control of the British colony and eventually succeeded in establishing independence. In the 19th century, New York's development of access to the interior beginning with the Erie Canal, gave it incomparable advantages over other regions of the U.S. east-coast and built its political and cultural ascendancy.Many landmarks in New York are well known, including four of the world's ten most-visited tourist attractions in 2013: Times Square, Central Park, Niagara Falls, and Grand Central Terminal. New York is home to the Statue of Liberty, a symbol of the United States and its ideals of freedom, democracy, and opportunity. In the 21st century, New York has emerged as a global node of creativity and entrepreneurship, social tolerance, and environmental sustainability. New York's higher education network comprises approximately 200 colleges and universities, including Columbia University, Cornell University, New York University, the United States Military Academy, the United States Merchant Marine Academy, University of Rochester, Rensselaer Polytechnic Institute, and Rockefeller University, which have been ranked among the top 40 in the nation and world.
What last name is mentioned which is also the name of a river located in New York?
6f3d17ddb0220c912a6090038ba01ef62d642022
en
Hudson
The state's most populous city, New York City, makes up over 40% of the state's population. Two-thirds of the state's population lives in the New York metropolitan area, and nearly 40% lives on Long Island. The state and city were both named for the 17th century Duke of York, the future King James II of England. With an estimated population of 8.62 million in 2017, New York City is the most populous city in the United States and the premier gateway for legal immigration to the United States. The New York metropolitan area is one of the most populous in the world. New York City is a global city, home to the United Nations Headquarters and has been described as the cultural, financial, and media capital of the world, as well as the world's most economically powerful city. The next four most populous cities in the state are Buffalo, Rochester, Yonkers, and Syracuse, while the state capital is Albany.
Who was New York City named after?
b7cd67ceebd3cbc9f12b70f8d794a2772d158a9c
en
Duke of York, the future King James II of England
Quantico, initially scheduled to air Tuesdays at 10:00 pm, was moved to Sundays at 10:00 pm due to a retooling of Of Kings and Prophets. The series premiered on ABC on Sunday, September 27, 2015. The series debuted in Canada on CTV on the same day as its American premiere. The episodes, about 43 minutes in length, were broadcast in standard and high definition. In Australia, it premiered on the Seven Network on October 11, 2015. The series was acquired by Alibi in the United Kingdom. Season two premiered on September 25, 2016. After the mid-season finale, it moved to Mondays at 10:00 p.m. on January 23, 2017. The third season premiered on April 26, 2018. After the cancellation, it was announced that the network will air the remaining episodes of the third season, as previously scheduled, on Friday nights.Standard- and high-definition episodes are available for download at the iTunes Store and Amazon Video, and ABC video on demand temporarily releases recent episodes. Season one episodes were on Hulu, and season two episodes are available at ABC's Quantico website and on Xfinity. The first season became available for streaming on Netflix in a number of countries on August 23, 2016, the second season became available in the U.S. on June 15, 2017 and the third season became available in the U.S. on September 2, 2018.
Quantico premiered on which channel?
d22cacaad370af857a67e14e6ab626d5f9e61bf5
en
ABC
In 2000, the Census estimated at least 1,408 same-sex households in Milwaukee, or about 0.6% of all households in the city. Gay-friendly communities have developed primarily in Walker's Point, but also in Bay View, Historic Third Ward, Washington Heights, Riverwest, and the East Side. In 2001, Milwaukee was named the #1 city for lesbians by Girlfriends magazine.The city's population is spread out with 28.6% under the age of 18, 12.2% from 18 to 24, 30.2% from 25 to 44, 18.1% from 45 to 64, and 10.9% who are 65 years of age or older. The median age is 31 years. For every 100 females, there are 91.6 males. For every 100 females age 18 and over, there are 87.2 males.
What is the median age of Milwaukee's population?
d4169d9955b1a399310ae6abfef25dcb12f86c05
en
31
In 2000, the Census estimated at least 1,408 same-sex households in Milwaukee, or about 0.6% of all households in the city. Gay-friendly communities have developed primarily in Walker's Point, but also in Bay View, Historic Third Ward, Washington Heights, Riverwest, and the East Side. In 2001, Milwaukee was named the #1 city for lesbians by Girlfriends magazine.The city's population is spread out with 28.6% under the age of 18, 12.2% from 18 to 24, 30.2% from 25 to 44, 18.1% from 45 to 64, and 10.9% who are 65 years of age or older. The median age is 31 years. For every 100 females, there are 91.6 males. For every 100 females age 18 and over, there are 87.2 males.
what was Milwaukee ranked number 1 for in 2001?
ac8c40a9630cf19615fc805551f5d34eb997a596
en
for lesbians
The median income for a household in the city is $32,216, and the median income for a family is $37,879. Males have a median income of $32,244 versus $26,013 for females. The per capita income for the city is $16,181. 21.3% of the population and 17.4% of families are below the poverty line. In 2010, rent increased an averaged 3% for home renters in Milwaukee. Out of the total population, 31.6% of those under the age of 18 and 11.0% of those 65 and older are living below the poverty line.
What is the per capita income of Milwaukee?
10f52025ac4f154c5107463acf010b73fc3afbb6
en
$16,181
Remote uploading is used by some online file hosting services. It is also used when the local computer has a slow connection to the remote systems, but they have a fast connection between them. Without remote uploading functionality, the data would have to first be downloaded to the local host and then uploaded to the remote file hosting server, both times over slow connections.
What online services use remote uploading?
545d6c6acf20c02181312ac5824ecfcd8f5b0939
en
file hosting services
Lina Medina was born in Ticrapo, Castrovirreyna Province, Peru, to silversmith Tiburelo Medina and Victoria Losea. Her parents brought her to a hospital at age five due to increasing abdominal size. Doctors originally thought that she had a tumor, but they then determined that she was in her seventh month of pregnancy. Dr Gerardo Lozada took her to Lima to have other specialists confirm that she was pregnant.Newspaper accounts indicate that interest in the case developed on many fronts. The San Antonio Light newspaper in Texas reported in its 16 July 1939 edition that a Peruvian obstetrician and midwife association had demanded that she be transported to a national maternity hospital. The paper quoted reports in the Peruvian paper La Crónica that an American film studio had sent down a representative "with authority to offer the sum of $5,000 to benefit the minor" in exchange for filming rights, but "we know that the offer was rejected". The article noted that Lozada had made films of Medina for scientific documentation and had shown them while addressing Peru's National Academy of Medicine; some baggage carrying the films had fallen into a river on a visit to the girl's hometown, but enough of his "pictorial record" remained to "intrigue the learned savants".A month and a half after the original diagnosis, Medina gave birth to a boy by caesarean section. She was 5 years, 7 months, and 21 days old, the youngest person in history to give birth. The caesarean birth was necessitated by her small pelvis. The surgery was performed by Lozada and Dr Busalleu, with Dr Colareta providing anaesthesia. The doctors found that she already had fully mature sexual organs from precocious puberty. Dr. Edmundo Escomel reported her case in the medical journal La Presse Médicale, including the additional details that her menarche had occurred at eight months of age, in contrast to a past report stating that she had been having regular periods since she was three years old (or 2½ according to a different article).Medina's son weighed 2.7 kg (6.0 lb; 0.43 st) at birth and was named Gerardo after her doctor. He was raised believing that Medina was his sister, but he found out at age 10 that she was his mother.
Who was the anesthesiologist during the surgery?
ea6ec32474222a7ce9b7f6dfe1ac58de16aa10ca
en
Dr Colareta
Medina has never revealed the father of the child nor the circumstances of her impregnation. Escomel suggested that she might not actually know herself, as she "couldn't give precise responses". Lina's father was arrested on suspicion of child sexual abuse, but he was released due to lack of evidence and the biological father was never identified. Her son grew up healthy. He died in 1979 at the age of 40.In young adulthood, Medina worked as a secretary in the Lima clinic of Lozada, which gave her an education and helped put her son through high school. She married Raúl Jurado, who fathered her second son in 1972. As of 2002, they lived in a poor district of Lima known as "Chicago Chico". She refused an interview with Reuters that year, just as she had turned away many reporters in years past.
Where did they live as of 2002?
b8682fcc474fd55c0af13f47a0a8426bd8f2a1e8
en
Chicago Chico
Medina has never revealed the father of the child nor the circumstances of her impregnation. Escomel suggested that she might not actually know herself, as she "couldn't give precise responses". Lina's father was arrested on suspicion of child sexual abuse, but he was released due to lack of evidence and the biological father was never identified. Her son grew up healthy. He died in 1979 at the age of 40.In young adulthood, Medina worked as a secretary in the Lima clinic of Lozada, which gave her an education and helped put her son through high school. She married Raúl Jurado, who fathered her second son in 1972. As of 2002, they lived in a poor district of Lima known as "Chicago Chico". She refused an interview with Reuters that year, just as she had turned away many reporters in years past.
What didn't Medina reveal regarding her impregnation?
92cf8bfc921965d77eba7f8b8b8585ee84c2ed8e
en
the father of the child nor the circumstances of her impregnation
Rai worked as a fashion and swimwear model prior to working in the adult industry. Rai was a stripper for 12 years prior to appearing in pornographic films. She entered the adult film industry in 2007 at the age of 29.In June 2013, she announced her retirement from adult films to focus on her mainstream career and personal life. Rai played the lead role of "Isis" in the mainstream horror film Isis Rising: Curse Of The Lady Mummy. In 2014, she was still touring as a feature stripper. On March 22, 2018, Priya announced her comeback after a six-year hiatus.She has expressed her opposition towards Measure B, a law requiring pornographic actors to wear condoms during all sex scenes filmed in Los Angeles, California.
What did Ria do after her work as a swimwear model?
3fd73bb702c42ee8d6f1ce76ef3c753d5a74cee6
en
stripper
HDPE has high tensile strength. It is used in products and packaging such as milk jugs, detergent bottles, butter tubs, garbage containers, and water pipes. One-third of all toys are manufactured from HDPE. In 2007, the global HDPE consumption reached a volume of more than 30 million tons.
How many millions of tons did global HDPE consumption reach in 2007?
d6775be80f3ba2a00a0747aa59746dd0a44c0c65
en
30
As of 2014, approximately one billion adults or ~22% of the population of the world have hypertension. It is slightly more frequent in men, in those of low socioeconomic status, and it becomes more common with age. It is common in high, medium, and low income countries. In 2004 rates of high blood pressure were highest in Africa, (30% for both sexes) and lowest in the Americas (18% for both sexes). Rates also vary markedly within regions with rates as low as 3.4% (men) and 6.8% (women) in rural India and as high as 68.9% (men) and 72.5% (women) in Poland. Rates in Africa were about 45% in 2016.In Europe hypertension occurs in about 30-45% of people as of 2013. In 1995 it was estimated that 43 million people (24% of the population) in the United States had hypertension or were taking antihypertensive medication. By 2004 this had increased to 29% and further to 32% (76 million US adults) by 2017. In 2017, with the change in definitions for hypertension, 46% of people in the United States are affected. African-American adults in the United States have among the highest rates of hypertension in the world at 44%. It is also more common in Filipino Americans and less common in US whites and Mexican Americans. Differences in hypertension rates are multifactorial and under study.
How many adults in billions have hypertension?
f29ed0f8b2d2d97291cf7b41db773105d3faefc1
en
one
Descriptions of hypertension as a disease came among others from Thomas Young in 1808 and especially Richard Bright in 1836. The first report of elevated blood pressure in a person without evidence of kidney disease was made by Frederick Akbar Mahomed (1849–1884).
When did the descriptions of hypertension come along?
e84177c67b7c7b03c2b1c613705316635c6a982e
en
1808
Failure to thrive, seizures, irritability, lack of energy, and difficulty in breathing can be associated with hypertension in newborns and young infants. In older infants and children, hypertension can cause headache, unexplained irritability, fatigue, failure to thrive, blurred vision, nosebleeds, and facial paralysis.
What is one reason young humans might experience difficulty moving their face as part of a larger issue?
b77547691f3f5206a6a5647f8457d2013691c04f
en
hypertension
High blood pressure is the most common chronic medical problem prompting visits to primary health care providers in USA. The American Heart Association estimated the direct and indirect costs of high blood pressure in 2010 as $76.6 billion. In the US 80% of people with hypertension are aware of their condition, 71% take some antihypertensive medication, but only 48% of people aware that they have hypertension adequately control it. Adequate management of hypertension can be hampered by inadequacies in the diagnosis, treatment, or control of high blood pressure. Health care providers face many obstacles to achieving blood pressure control, including resistance to taking multiple medications to reach blood pressure goals. People also face the challenges of adhering to medicine schedules and making lifestyle changes. Nonetheless, the achievement of blood pressure goals is possible, and most importantly, lowering blood pressure significantly reduces the risk of death due to heart disease and stroke, the development of other debilitating conditions, and the cost associated with advanced medical care.
In 2010, what was the cost of high blood pressure?
115ea90ffe86ecc5d9717f9edcd69a100efc7143
en
$76.6 billion
Hypertension is the most important preventable risk factor for premature death worldwide. It increases the risk of ischemic heart disease, strokes, peripheral vascular disease, and other cardiovascular diseases, including heart failure, aortic aneurysms, diffuse atherosclerosis, chronic kidney disease, atrial fibrillation, and pulmonary embolism. Hypertension is also a risk factor for cognitive impairment and dementia. Other complications include hypertensive retinopathy and hypertensive nephropathy.
What does hypertension increase?
00df95637d0fc0837b9eba5dafceb545856459b9
en
the risk of ischemic heart disease, strokes, peripheral vascular disease, and other cardiovascular diseases
Hypertension occurs in approximately 8–10% of pregnancies. Two blood pressure measurements six hours apart of greater than 140/90 mm Hg are diagnostic of hypertension in pregnancy. High blood pressure in pregnancy can be classified as pre-existing hypertension, gestational hypertension, or pre-eclampsia.Pre-eclampsia is a serious condition of the second half of pregnancy and following delivery characterised by increased blood pressure and the presence of protein in the urine. It occurs in about 5% of pregnancies and is responsible for approximately 16% of all maternal deaths globally. Pre-eclampsia also doubles the risk of death of the baby around the time of birth. Usually there are no symptoms in pre-eclampsia and it is detected by routine screening. When symptoms of pre-eclampsia occur the most common are headache, visual disturbance (often "flashing lights"), vomiting, pain over the stomach, and swelling. Pre-eclampsia can occasionally progress to a life-threatening condition called eclampsia, which is a hypertensive emergency and has several serious complications including vision loss, brain swelling, seizures, kidney failure, pulmonary edema, and disseminated intravascular coagulation (a blood clotting disorder).In contrast, gestational hypertension is defined as new-onset hypertension during pregnancy without protein in the urine.
what condition usually has no symptoms?
892e20cf8c340006123412c728f5ee7110572180
en
pre-eclampsia
Hypertension occurs in around 0.2 to 3% of newborns; however, blood pressure is not measured routinely in healthy newborns. Hypertension is more common in high risk newborns. A variety of factors, such as gestational age, postconceptional age and birth weight needs to be taken into account when deciding if a blood pressure is normal in a newborn.Hypertension defined as elevated blood pressure over several visits affects 1% to 5% of children and adolescents and is associated with long term risks of ill-health. Blood pressure rises with age in childhood and, in children, hypertension is defined as an average systolic or diastolic blood pressure on three or more occasions equal or higher than the 95th percentile appropriate for the sex, age and height of the child. High blood pressure must be confirmed on repeated visits however before characterizing a child as having hypertension. Prehypertension in children has been defined as average systolic or diastolic blood pressure that is greater than or equal to the 90th percentile, but less than the 95th percentile. In adolescents, it has been proposed that hypertension and pre-hypertension are diagnosed and classified using the same criteria as in adults.The value of routine screening for hypertension in children over the age of 3 years is debated. In 2004 the National High Blood Pressure Education Program recommended that children aged 3 years and older have blood pressure measurement at
What is the condition that is common in newborns?
71efffa3e3c1d3630b3ec1e4109c8d85aa2f273e
en
Hypertension
Hypertension occurs in around 0.2 to 3% of newborns; however, blood pressure is not measured routinely in healthy newborns. Hypertension is more common in high risk newborns. A variety of factors, such as gestational age, postconceptional age and birth weight needs to be taken into account when deciding if a blood pressure is normal in a newborn.Hypertension defined as elevated blood pressure over several visits affects 1% to 5% of children and adolescents and is associated with long term risks of ill-health. Blood pressure rises with age in childhood and, in children, hypertension is defined as an average systolic or diastolic blood pressure on three or more occasions equal or higher than the 95th percentile appropriate for the sex, age and height of the child. High blood pressure must be confirmed on repeated visits however before characterizing a child as having hypertension. Prehypertension in children has been defined as average systolic or diastolic blood pressure that is greater than or equal to the 90th percentile, but less than the 95th percentile. In adolescents, it has been proposed that hypertension and pre-hypertension are diagnosed and classified using the same criteria as in adults.The value of routine screening for hypertension in children over the age of 3 years is debated. In 2004 the National High Blood Pressure Education Program recommended that children aged 3 years and older have blood pressure measurement at
How is hypertension defined in children?
87c7cc6be5f8e7da5c1d4df15bf5a19daae13bbe
en
average systolic or diastolic blood pressure on three or more occasions equal or higher than the 95th percentile appropriate for the sex, age and height of the child
In people aged 18 years or older hypertension is defined as either a systolic or a diastolic blood pressure measurement consistently higher than an accepted normal value (this is above 129 or 139 mmHg systolic, 89 mmHg diastolic depending on the guideline). Other thresholds are used (135 mmHg systolic or 85 mmHg diastolic) if measurements are derived from 24-hour ambulatory or home monitoring. Recent international hypertension guidelines have also created categories below the hypertensive range to indicate a continuum of risk with higher blood pressures in the normal range. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC7) published in 2003 uses the term prehypertension for blood pressure in the range 120–139 mmHg systolic or 80–89 mmHg diastolic, while European Society of Hypertension Guidelines (2007) and British Hypertension Society (BHS) IV (2004) use optimal, normal and high normal categories to subdivide pressures below 140 mmHg systolic and 90 mmHg diastolic. Hypertension is also sub-classified: JNC7 distinguishes hypertension stage I, hypertension stage II, and isolated systolic hypertension. Isolated systolic hypertension refers to elevated systolic pressure with normal diastolic pressure and is common in the elderly. The ESH-ESC Guidelines (2007) and BHS IV (2004) additionally define a third stage (stage III hypertension) for people with systolic blood pressure exceeding 179 mmHg or a diastolic pressure over 109 mmHg. Hypertension is classified as "resistant" if medications do not reduce blood pressure to normal levels. In November 2017, the American Heart Association and American College of Cardiology published a joint guideline which updates the recommendations of the JNC7 report.
What is the third stage of hypertensions level of blood pressure?
d6d76338394c6414828179c0d07ad93ef6a248bf
en
exceeding 179 mmHg or a diastolic pressure over 109 mmHg
In the 19th and 20th centuries, before effective pharmacological treatment for hypertension became possible, three treatment modalities were used, all with numerous side-effects: strict sodium restriction (for example the rice diet), sympathectomy (surgical ablation of parts of the sympathetic nervous system), and pyrogen therapy (injection of substances that caused a fever, indirectly reducing blood pressure).The first chemical for hypertension, sodium thiocyanate, was used in 1900 but had many side effects and was unpopular. Several other agents were developed after the Second World War, the most popular and reasonably effective of which were tetramethylammonium chloride, hexamethonium, hydralazine, and reserpine (derived from the medicinal plant Rauwolfia serpentina). None of these were well tolerated. A major breakthrough was achieved with the discovery of the first well-tolerated orally available agents. The first was chlorothiazide, the first thiazide diuretic and developed from the antibiotic sulfanilamide, which became available in 1958. Subsequently, beta blockers, calcium channel blockers, angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers, and renin inhibitors were developed as antihypertensive agents.
What is the drug derived from Rauwolfia plant?
5b4172fa39234f7755a6615269035a8fc90b0bbb
en
reserpine
Modern understanding of the cardiovascular system began with the work of physician William Harvey (1578–1657), who described the circulation of blood in his book "De motu cordis". The English clergyman Stephen Hales made the first published measurement of blood pressure in 1733. However, hypertension as a clinical entity came into its own with the invention of the cuff-based sphygmomanometer by Scipione Riva-Rocci in 1896. This allowed easy measurement of systolic pressure in the clinic. In 1905, Nikolai Korotkoff improved the technique by describing the Korotkoff sounds that are heard when the artery is ausculted with a stethoscope while the sphygmomanometer cuff is deflated. This permitted systolic and diastolic pressure to be measured.
In what year did Scipione Riva-Rocci invent the sphygmomanometer
4e0f843d642d715f22de2f205f0a498dc090bc60
en
1896
Modern understanding of the cardiovascular system began with the work of physician William Harvey (1578–1657), who described the circulation of blood in his book "De motu cordis". The English clergyman Stephen Hales made the first published measurement of blood pressure in 1733. However, hypertension as a clinical entity came into its own with the invention of the cuff-based sphygmomanometer by Scipione Riva-Rocci in 1896. This allowed easy measurement of systolic pressure in the clinic. In 1905, Nikolai Korotkoff improved the technique by describing the Korotkoff sounds that are heard when the artery is ausculted with a stethoscope while the sphygmomanometer cuff is deflated. This permitted systolic and diastolic pressure to be measured.
What book did William Harvey write?
e97ae381ec1f8a2455e4cb7277000d88da26426a
en
De motu cordis
Once the diagnosis of hypertension has been made, healthcare providers should attempt to identify the underlying cause based on risk factors and other symptoms, if present. Secondary hypertension is more common in preadolescent children, with most cases caused by kidney disease. Primary or essential hypertension is more common in adolescents and adults and has multiple risk factors, including obesity and a family history of hypertension. Laboratory tests can also be performed to identify possible causes of secondary hypertension, and to determine whether hypertension has caused damage to the heart, eyes, and kidneys. Additional tests for diabetes and high cholesterol levels are usually performed because these conditions are additional risk factors for the development of heart disease and may require treatment.Initial assessment of the hypertensive people should include a complete history and physical examination. Serum creatinine is measured to assess for the presence of kidney disease, which can be either the cause or the result of hypertension. Serum creatinine alone may overestimate glomerular filtration rate and recent guidelines advocate the use of predictive equations such as the Modification of Diet in Renal Disease (MDRD) formula to estimate glomerular filtration rate (eGFR). eGFR can also provide a baseline measurement of kidney function that can be used to monitor for side effects of certain anti-hypertensive drugs on kidney function. Additionally, testing of urine samples for protein is used as a secondary indicator of kidney disease. Electrocardiogram (EKG/ECG) testing is done to check for evidence that the heart is under strain from high blood pressure. It may also show whether there is thickening of the heart muscle (left ventricular hypertrophy) or whether the heart has experienced a prior minor disturbance such as a silent heart attack. A chest X-ray or an echocardiogram may also be performed to look for signs of heart enlargement or damage to the heart.
What bodily fluid is used to test for kidney problems?
01b793014fbd87d8be9368f08eec683d2e1cc055
en
urine
Once the diagnosis of hypertension has been made, healthcare providers should attempt to identify the underlying cause based on risk factors and other symptoms, if present. Secondary hypertension is more common in preadolescent children, with most cases caused by kidney disease. Primary or essential hypertension is more common in adolescents and adults and has multiple risk factors, including obesity and a family history of hypertension. Laboratory tests can also be performed to identify possible causes of secondary hypertension, and to determine whether hypertension has caused damage to the heart, eyes, and kidneys. Additional tests for diabetes and high cholesterol levels are usually performed because these conditions are additional risk factors for the development of heart disease and may require treatment.Initial assessment of the hypertensive people should include a complete history and physical examination. Serum creatinine is measured to assess for the presence of kidney disease, which can be either the cause or the result of hypertension. Serum creatinine alone may overestimate glomerular filtration rate and recent guidelines advocate the use of predictive equations such as the Modification of Diet in Renal Disease (MDRD) formula to estimate glomerular filtration rate (eGFR). eGFR can also provide a baseline measurement of kidney function that can be used to monitor for side effects of certain anti-hypertensive drugs on kidney function. Additionally, testing of urine samples for protein is used as a secondary indicator of kidney disease. Electrocardiogram (EKG/ECG) testing is done to check for evidence that the heart is under strain from high blood pressure. It may also show whether there is thickening of the heart muscle (left ventricular hypertrophy) or whether the heart has experienced a prior minor disturbance such as a silent heart attack. A chest X-ray or an echocardiogram may also be performed to look for signs of heart enlargement or damage to the heart.
how do you find out hypertension?
05d39419d02a64797526e0be53cbc6da9ccf4b1d
en
Laboratory tests
Once the diagnosis of hypertension has been made, healthcare providers should attempt to identify the underlying cause based on risk factors and other symptoms, if present. Secondary hypertension is more common in preadolescent children, with most cases caused by kidney disease. Primary or essential hypertension is more common in adolescents and adults and has multiple risk factors, including obesity and a family history of hypertension. Laboratory tests can also be performed to identify possible causes of secondary hypertension, and to determine whether hypertension has caused damage to the heart, eyes, and kidneys. Additional tests for diabetes and high cholesterol levels are usually performed because these conditions are additional risk factors for the development of heart disease and may require treatment.Initial assessment of the hypertensive people should include a complete history and physical examination. Serum creatinine is measured to assess for the presence of kidney disease, which can be either the cause or the result of hypertension. Serum creatinine alone may overestimate glomerular filtration rate and recent guidelines advocate the use of predictive equations such as the Modification of Diet in Renal Disease (MDRD) formula to estimate glomerular filtration rate (eGFR). eGFR can also provide a baseline measurement of kidney function that can be used to monitor for side effects of certain anti-hypertensive drugs on kidney function. Additionally, testing of urine samples for protein is used as a secondary indicator of kidney disease. Electrocardiogram (EKG/ECG) testing is done to check for evidence that the heart is under strain from high blood pressure. It may also show whether there is thickening of the heart muscle (left ventricular hypertrophy) or whether the heart has experienced a prior minor disturbance such as a silent heart attack. A chest X-ray or an echocardiogram may also be performed to look for signs of heart enlargement or damage to the heart.
What is the first step after hypertension has been made?
a759e6a606ce90aec3e072f1aa0f5468060cee92
en
healthcare providers should attempt to identify the underlying cause
Once the diagnosis of hypertension has been made, healthcare providers should attempt to identify the underlying cause based on risk factors and other symptoms, if present. Secondary hypertension is more common in preadolescent children, with most cases caused by kidney disease. Primary or essential hypertension is more common in adolescents and adults and has multiple risk factors, including obesity and a family history of hypertension. Laboratory tests can also be performed to identify possible causes of secondary hypertension, and to determine whether hypertension has caused damage to the heart, eyes, and kidneys. Additional tests for diabetes and high cholesterol levels are usually performed because these conditions are additional risk factors for the development of heart disease and may require treatment.Initial assessment of the hypertensive people should include a complete history and physical examination. Serum creatinine is measured to assess for the presence of kidney disease, which can be either the cause or the result of hypertension. Serum creatinine alone may overestimate glomerular filtration rate and recent guidelines advocate the use of predictive equations such as the Modification of Diet in Renal Disease (MDRD) formula to estimate glomerular filtration rate (eGFR). eGFR can also provide a baseline measurement of kidney function that can be used to monitor for side effects of certain anti-hypertensive drugs on kidney function. Additionally, testing of urine samples for protein is used as a secondary indicator of kidney disease. Electrocardiogram (EKG/ECG) testing is done to check for evidence that the heart is under strain from high blood pressure. It may also show whether there is thickening of the heart muscle (left ventricular hypertrophy) or whether the heart has experienced a prior minor disturbance such as a silent heart attack. A chest X-ray or an echocardiogram may also be performed to look for signs of heart enlargement or damage to the heart.
What is the acronym for Electrocardiogram?
e6ea06caaa1deb4f675c8f6abad569df1c8641f6
en
EKG/ECG
The World Health Organization has identified hypertension, or high blood pressure, as the leading cause of cardiovascular mortality. The World Hypertension League (WHL), an umbrella organization of 85 national hypertension societies and leagues, recognized that more than 50% of the hypertensive population worldwide are unaware of their condition. To address this problem, the WHL initiated a global awareness campaign on hypertension in 2005 and dedicated May 17 of each year as World Hypertension Day (WHD). Over the past three years, more national societies have been engaging in WHD and have been innovative in their activities to get the message to the public. In 2007, there was record participation from 47 member countries of the WHL. During the week of WHD, all these countries – in partnership with their local governments, professional societies, nongovernmental organizations and private industries – promoted hypertension awareness among the public through several media and public rallies. Using mass media such as Internet and television, the message reached more than 250 million people. As the momentum picks up year after year, the WHL is confident that almost all the estimated 1.5 billion people affected by elevated blood pressure can be reached.
For how many years have national societies been participating in WHD pursuits?
5ec293e4a924587a28d20f57359d4c4b93fcb191
en
three years,
The World Health Organization has identified hypertension, or high blood pressure, as the leading cause of cardiovascular mortality. The World Hypertension League (WHL), an umbrella organization of 85 national hypertension societies and leagues, recognized that more than 50% of the hypertensive population worldwide are unaware of their condition. To address this problem, the WHL initiated a global awareness campaign on hypertension in 2005 and dedicated May 17 of each year as World Hypertension Day (WHD). Over the past three years, more national societies have been engaging in WHD and have been innovative in their activities to get the message to the public. In 2007, there was record participation from 47 member countries of the WHL. During the week of WHD, all these countries – in partnership with their local governments, professional societies, nongovernmental organizations and private industries – promoted hypertension awareness among the public through several media and public rallies. Using mass media such as Internet and television, the message reached more than 250 million people. As the momentum picks up year after year, the WHL is confident that almost all the estimated 1.5 billion people affected by elevated blood pressure can be reached.
Which organization created World Hypertension Day for awareness of hypertension?
cdeacee23dab19773a4d50ade89f7d0fadf605a6
en
World Hypertension League
The World Health Organization has identified hypertension, or high blood pressure, as the leading cause of cardiovascular mortality. The World Hypertension League (WHL), an umbrella organization of 85 national hypertension societies and leagues, recognized that more than 50% of the hypertensive population worldwide are unaware of their condition. To address this problem, the WHL initiated a global awareness campaign on hypertension in 2005 and dedicated May 17 of each year as World Hypertension Day (WHD). Over the past three years, more national societies have been engaging in WHD and have been innovative in their activities to get the message to the public. In 2007, there was record participation from 47 member countries of the WHL. During the week of WHD, all these countries – in partnership with their local governments, professional societies, nongovernmental organizations and private industries – promoted hypertension awareness among the public through several media and public rallies. Using mass media such as Internet and television, the message reached more than 250 million people. As the momentum picks up year after year, the WHL is confident that almost all the estimated 1.5 billion people affected by elevated blood pressure can be reached.
What is the WHL doing to address hypertension?
834152db11e91de3c0a8e3a34e741544adc5e670
en
global awareness campaign on hypertension
limit alcohol consumption to no more than 3 units/day in men and no more than 2 units/day in women
Many many units are recommended for women?
748a626fc2c6629ff857db79e5a0d13482cd5a3a
en
2 units/day
Scientific theories are sometimes labeled "numerology" if their primary inspiration appears to be a set of patterns rather than scientific observations. This colloquial use of the term is quite common within the scientific community and it is mostly used to dismiss a theory as questionable science.
what are scientific methods sometimes labeled as?
73cc67cd7c4339eb07684e3d5828341bd563a6f8
en
numerology
Scientific theories are sometimes labeled "numerology" if their primary inspiration appears to be a set of patterns rather than scientific observations. This colloquial use of the term is quite common within the scientific community and it is mostly used to dismiss a theory as questionable science.
The term is commonly used in what community?
75108fda82d4c85be7224e1d8094e73292267a4c
en
scientific
This governorate borders the Red Sea and is part of the narrow Tihamah region. Its capital, Al Hudaydah, also serves as an important local port city.
What ocean does the governorate border?
225f0653fc179789871937f288b1dbb9804b787c
en
Red Sea
Both the Olympics and 2014 Winter Paralympics were organized by the Sochi Organizing Committee (SOOC). Sochi was selected as the host city in July 2007, during the 119th IOC Session held in Guatemala City. It was the first Olympics to be held in a CIS state since the breakup of the Soviet Union in 1991. The Soviet Union was previously the host nation for the 1980 Summer Olympics in Moscow. These were the first Olympic Games under the International Olympic Committee (IOC) presidency of Thomas Bach.
Which city hosted the Olymipics in 2007?
9fc3f8c6582caf030eaa93884ff4e835d5d71142
en
Sochi
Sochi's medal design was unveiled in May 2013. The design is intended to resemble Sochi's landscape, with a semi-translucent section containing a "patchwork quilt" of diamonds representing mountains; the diamonds themselves contain designs that reflect Russia's regions. Those who won gold medals on 15 February received special medals with fragments of the Chelyabinsk meteor, marking the one-year anniversary of the event where pieces of the cosmic body fell into the Chebarkul Lake in the Ural Mountains in central Russia.
Where did the Chelyabinsk meteor fall?
e40c0d48656b9e89ffbda0e412ba2c139657dba4
en
the Chebarkul Lake in the Ural Mountains in central Russia
Brisbane ( (listen)) is the capital of and the most populated city in the Australian state of Queensland, and the third most populous city in Australia. Brisbane's metropolitan area has a population of approximately 2.5 million, and the South East Queensland metropolitan region, centred on Brisbane, encompasses a population of more than 3.6 million. The Brisbane central business district stands on the historic European settlement and is situated inside a peninsula of the Brisbane River, about 15 kilometres (9 miles) from its mouth at Moreton Bay. The metropolitan area extends in all directions along the floodplain of the Brisbane River Valley between Moreton Bay and the Great Dividing Range, sprawling across several of Australia's most populous local government areas (LGAs)—most centrally the City of Brisbane, which is by far the most populous LGA in the nation. The demonym of Brisbane is "Brisbanite" or "Brisbanian".One of the oldest cities in Australia, Brisbane was founded upon the ancient homelands of the indigenous Turrbal and Jagera peoples. Named after the Brisbane River on which it is located—which in turn takes its name from the Scotsman Sir Thomas Brisbane, the Governor of New South Wales from 1821 to 1825—the area was chosen as a place for secondary offenders from the Sydney Colony. A penal settlement was founded in 1824 at Redcliffe, 28 kilometres (17 mi) north of the central business district, but was soon abandoned and moved to North Quay in 1825, opening to free settlement in 1842. There was conflict between the European people and the Aboriginal people from 1843 to 1855. The development was partly set back by the Great Fire of Brisbane of 1864, and the Great Brisbane Flood of 1893. Brisbane was chosen as the capital when Queensland was proclaimed a separate colony from New South Wales in 1859. During World War II, Brisbane played a central role in the Allied campaign and served as the South West Pacific headquarters for United States Army General Douglas MacArthur.Today, Brisbane is well known for its distinct Queenslander architecture which forms much of the city's built heritage. It also received attention for its damaging flood events, most notably in 1974 and 2011. Major landmarks and precincts include; the South Bank Parklands and the Queensland Cultural Centre, City Hall and King George Square, the Story Bridge, the City Botanic Gardens and Parliament of Queensland, ANZAC Square, Howard Smith Wharves, Fortitude Valley, West End, Roma Street Parkland, New Farm Park and the Brisbane Powerhouse, St John's Cathedral, Mount Coot-tha, Redcliffe and Moreton and Stradbroke Islands. The city is a popular tourist destination, serving as a gateway to the state of Queensland, particularly to the Gold Coast and Sunshine Coast, popular resort areas immediately south and north of Brisbane respectively. Several large cultural, international and sporting events have been held at Brisbane, including the 1982 Commonwealth Games, World Expo '88, the final Goodwill Games in 2001, and the 2014 G-20 summit. In 2016, the Globalization and World Cities Research Network ranked Brisbane as a Beta world city.
When was the penal settlement founded?
fe3c8a54d354de1d71d11b10171eec50e050035e
en
1824
Brisbane ( (listen)) is the capital of and the most populated city in the Australian state of Queensland, and the third most populous city in Australia. Brisbane's metropolitan area has a population of approximately 2.5 million, and the South East Queensland metropolitan region, centred on Brisbane, encompasses a population of more than 3.6 million. The Brisbane central business district stands on the historic European settlement and is situated inside a peninsula of the Brisbane River, about 15 kilometres (9 miles) from its mouth at Moreton Bay. The metropolitan area extends in all directions along the floodplain of the Brisbane River Valley between Moreton Bay and the Great Dividing Range, sprawling across several of Australia's most populous local government areas (LGAs)—most centrally the City of Brisbane, which is by far the most populous LGA in the nation. The demonym of Brisbane is "Brisbanite" or "Brisbanian".One of the oldest cities in Australia, Brisbane was founded upon the ancient homelands of the indigenous Turrbal and Jagera peoples. Named after the Brisbane River on which it is located—which in turn takes its name from the Scotsman Sir Thomas Brisbane, the Governor of New South Wales from 1821 to 1825—the area was chosen as a place for secondary offenders from the Sydney Colony. A penal settlement was founded in 1824 at Redcliffe, 28 kilometres (17 mi) north of the central business district, but was soon abandoned and moved to North Quay in 1825, opening to free settlement in 1842. There was conflict between the European people and the Aboriginal people from 1843 to 1855. The development was partly set back by the Great Fire of Brisbane of 1864, and the Great Brisbane Flood of 1893. Brisbane was chosen as the capital when Queensland was proclaimed a separate colony from New South Wales in 1859. During World War II, Brisbane played a central role in the Allied campaign and served as the South West Pacific headquarters for United States Army General Douglas MacArthur.Today, Brisbane is well known for its distinct Queenslander architecture which forms much of the city's built heritage. It also received attention for its damaging flood events, most notably in 1974 and 2011. Major landmarks and precincts include; the South Bank Parklands and the Queensland Cultural Centre, City Hall and King George Square, the Story Bridge, the City Botanic Gardens and Parliament of Queensland, ANZAC Square, Howard Smith Wharves, Fortitude Valley, West End, Roma Street Parkland, New Farm Park and the Brisbane Powerhouse, St John's Cathedral, Mount Coot-tha, Redcliffe and Moreton and Stradbroke Islands. The city is a popular tourist destination, serving as a gateway to the state of Queensland, particularly to the Gold Coast and Sunshine Coast, popular resort areas immediately south and north of Brisbane respectively. Several large cultural, international and sporting events have been held at Brisbane, including the 1982 Commonwealth Games, World Expo '88, the final Goodwill Games in 2001, and the 2014 G-20 summit. In 2016, the Globalization and World Cities Research Network ranked Brisbane as a Beta world city.
Brisbane was settled by what population?
3cb5201422dbbbb3dc9b4774ea84a653b2a5a8df
en
secondary offenders from the Sydney Colony
Approximately 30,000 species of flora and fauna have been registered in Latvia. Common species of wildlife in Latvia include deer, wild boar, moose, lynx, bear, fox, beaver and wolves. Non-marine molluscs of Latvia include 159 species.Species that are endangered in other European countries but common in Latvia include: black stork (Ciconia nigra), corncrake (Crex crex), lesser spotted eagle (Aquila pomarina), white-backed woodpecker (Picoides leucotos), Eurasian crane (Grus grus), Eurasian beaver (Castor fiber), Eurasian otter (Lutra lutra), European wolf (Canis lupus) and European lynx (Felis lynx).Phytogeographically, Latvia is shared between the Central European and Northern European provinces of the Circumboreal Region within the Boreal Kingdom. According to the WWF, the territory of Latvia belongs to the ecoregion of Sarmatic mixed forests. 56 percent of Latvia's territory is covered by forests, mostly Scots pine, birch, and Norway spruce.Several species of flora and fauna are considered national symbols. Oak (Quercus robur, Latvian: ozols), and linden (Tilia cordata, Latvian: liepa) are Latvia's national trees and the daisy (Leucanthemum vulgare, Latvian: pīpene) its national flower. The white wagtail (Motacilla alba, Latvian: baltā cielava) is Latvia's national bird. Its national insect is the two-spot ladybird (Adalia bipunctata, Latvian: divpunktu mārīte). Amber, fossilized tree resin, is one of Latvia's most important cultural symbols. In ancient times, amber found along the Baltic Sea coast was sought by Vikings as well as traders from Egypt, Greece and the Roman Empire. This led to the development of the Amber Road.Several nature reserves protect unspoiled landscapes with a variety of large animals. At Pape Nature Reserve, where European bison, wild horses, and recreated aurochs have been reintroduced, there is now an almost complete Holocene megafauna also including moose, deer, and wolf.
Are moose commonly or rarely found in Latvia?
9c04c4c9669e95984fe64a5081ec542029863f46
en
Common
Latvia is a member of the World Trade Organization (1999) and the European Union (2004). On 1 January 2014, the Euro became the country's currency, superseding the Lats. According to statistics in late 2013, 45% of the population supported the introduction of the euro, while 52% opposed it. Following the introduction of the Euro, Eurobarometer surveys in January 2014 showed support for the Euro to be around 53%, close to the European average.Since the year 2000, Latvia has had one of the highest (GDP) growth rates in Europe. However, the chiefly consumption-driven growth in Latvia resulted in the collapse of Latvian GDP in late 2008 and early 2009, exacerbated by the global economic crisis, shortage of credit and huge money resources used for the bailout of Parex bank. The Latvian economy fell 18% in the first three months of 2009, the biggest fall in the European Union.
When did Latvia join EU?
79304324228cbc50be2853daa15d76e952b1b0d8
en
2004
The Saeima, Latvia's parliament, was again elected in 1993. Russia ended its military presence by completing its troop withdrawal in 1994 and shutting down the Skrunda-1 radar station in 1998. The major goals of Latvia in the 1990s, to join NATO and the European Union, were achieved in 2004. The NATO Summit 2006 was held in Riga.Language and citizenship laws have been opposed by many Russophones. Citizenship was not automatically extended to former Soviet citizens who settled during the Soviet occupation, or to their offspring. Children born to non-nationals after the reestablishment of independence are automatically entitled to citizenship. Approximately 72% of Latvian citizens are Latvian, while 20% are Russian; less than 1% of non-citizens are Latvian, while 71% are Russian. The government denationalised private property confiscated by the Soviets, returning it or compensating the owners for it, and privatised most state-owned industries, reintroducing the prewar currency. Albeit having experienced a difficult transition to a liberal economy and its re-orientation toward Western Europe, Latvia is one of the fastest growing economies in the European Union. In 2014, Riga was the European Capital of Culture, the euro was introduced as the currency of the country and a Latvian was named vice-president of the European Commission. In 2015 Latvia held the presidency of Council of the European Union. Big European events have been celebrated in Riga such as the Eurovision Song Contest 2003 and the European Film Awards 2014. On 1 July 2016, Latvia became a member of the OECD.
What were Latvia's goal that were son met?
366f0fa1fb8925de0728a1f9e48f2a2d48757ff4
en
join NATO and the European Union
Globular clusters are among the oldest objects in the Milky Way, which thus set a lower limit on the age of the Milky Way. The ages of individual stars in the Milky Way can be estimated by measuring the abundance of long-lived radioactive elements such as thorium-232 and uranium-238, then comparing the results to estimates of their original abundance, a technique called nucleocosmochronology. These yield values of about 12.5 ± 3 billion years for CS 31082-001 and 13.8 ± 4 billion years for BD +17° 3248. Once a white dwarf is formed, it begins to undergo radiative cooling and the surface temperature steadily drops. By measuring the temperatures of the coolest of these white dwarfs and comparing them to their expected initial temperature, an age estimate can be made. With this technique, the age of the globular cluster M4 was estimated as 12.7 ± 0.7 billion years. Age estimates of the oldest of these clusters gives a best fit estimate of 12.6 billion years, and a 95% confidence upper limit of 16 billion years.In November 2018, astronomers reported the discovery of one of the oldest stars in the universe. About 13.5 billion-years-old, 2MASS J18082002-5104378 B is a tiny ultra metal-poor (UMP) star made almost entirely of materials released from the Big Bang, and is possibly one of the very first stars. The discovery of the star in the Milky Way galaxy suggests that the galaxy may be at least 3 billion years older than previously thought.Several individual stars have been found in the Milky Way's halo with measured ages very close to the 13.80-billion-year age of the Universe. In 2007, a star in the galactic halo, HE 1523-0901, was estimated to be about 13.2 billion years old. As the oldest known object in the Milky Way at that time, this measurement placed a lower limit on the age of the Milky Way. This estimate was made using the UV-Visual Echelle Spectrograph of the Very Large Telescope to measure the relative strengths of spectral lines caused by the presence of thorium and other elements created by the R-process. The line strengths yield abundances of different elemental isotopes, from which an estimate of the age of the star can be derived using nucleocosmochronology. Another star, HD 140283, is 14.5 ± 0.7 billion years old.According to observations utilizing adaptive optics to correct for Earth's atmospheric distortion, stars in the galaxy's bulge date to about 12.8 billion years old.The age of stars in the galactic thin disk has also been estimated using nucleocosmochronology. Measurements of thin disk stars yield an estimate that the thin disk formed 8.8 ± 1.7 billion years ago. These measurements suggest there was a hiatus of almost 5 billion years between the formation of the galactic halo and the thin disk. Recent analysis of the chemical signatures of thousands of stars suggests that stellar formation might have dropped by an order of magnitude at the time of disk formation, 10 to 8 billion years ago, when interstellar gas was too hot to form new stars at the same rate as before.The satellite galaxies surrounding the Milky way are not randomly distributed but seemed to be the result of a break-up of some larger system producing a ring structure 500,000 light years in diameter and 50,000 light-years wide. Close encounters between galaxies, like that expected in 4 billion years with the Andromeda Galaxy rips off huge tails of gas, which, over time can coalesce to form dwarf galaxies in a ring at an arbitrary angle to the main disc.
How old is the star in HE 1523-0901?
9648c68e13734e33f5fdc7263377839fbd3f4121
en
13.2 billion years old
Although she was hostile to the suffragist goals of first-wave feminism, Goldman advocated passionately for the rights of women, and is today heralded as a founder of anarcha-feminism, which challenges patriarchy as a hierarchy to be resisted alongside state power and class divisions. In 1897, she wrote: "I demand the independence of woman, her right to support herself; to live for herself; to love whomever she pleases, or as many as she pleases. I demand freedom for both sexes, freedom of action, freedom in love and freedom in motherhood."A nurse by training, Goldman was an early advocate for educating women concerning contraception. Like many feminists of her time, she saw abortion as a tragic consequence of social conditions, and birth control as a positive alternative. Goldman was also an advocate of free love, and a strong critic of marriage. She saw early feminists as confined in their scope and bounded by social forces of Puritanism and capitalism. She wrote: "We are in need of unhampered growth out of old traditions and habits. The movement for women's emancipation has so far made but the first step in that direction."Goldman was also an outspoken critic of prejudice against homosexuals. Her belief that social liberation should extend to gay men and lesbians was virtually unheard of at the time, even among anarchists. As German sexologist Magnus Hirschfeld wrote, "she was the first and only woman, indeed the first and only American, to take up the defense of homosexual love before the general public." In numerous speeches and letters, she defended the right of gay men and lesbians to love as they pleased and condemned the fear and stigma associated with homosexuality. As Goldman wrote in a letter to Hirschfeld, "It is a tragedy, I feel, that people of a different sexual type are caught in a world which shows so little understanding for homosexuals and is so crassly indifferent to the various gradations and variations of gender and their great significance in life."
What did Goldman consider as a positive alternative to abortion?
67039cc7eb8ed95167f451cafdd0fa661cb61b05
en
birth control
Emma Goldman: A Documentary History of the American Years, Volume 1 – Made for America, 1890–1901. Berkeley: University of California Press, 2003. ISBN 0-520-08670-8.
What was the year span that the documentary was based on?
e1b878128e37ff7b9bb8a619aa8ba8305ee462d6
en
1890–1901
In 1906, Goldman decided to start a publication, "a place of expression for the young idealists in arts and letters". Mother Earth was staffed by a cadre of radical activists, including Hippolyte Havel, Max Baginski, and Leonard Abbott. In addition to publishing original works by its editors and anarchists around the world, Mother Earth reprinted selections from a variety of writers. These included the French philosopher Pierre-Joseph Proudhon, Russian anarchist Peter Kropotkin, German philosopher Friedrich Nietzsche, and British writer Mary Wollstonecraft. Goldman wrote frequently about anarchism, politics, labor issues, atheism, sexuality, and feminism, and was the first editor of the magazine.On May 18 of the same year, Alexander Berkman was released from prison. Carrying a bouquet of roses, Goldman met him on the train platform and found herself "seized by terror and pity" as she beheld his gaunt, pale form. Neither was able to speak; they returned to her home in silence. For weeks, he struggled to readjust to life on the outside. An abortive speaking tour ended in failure, and in Cleveland he purchased a revolver with the intent of killing himself. He returned to New York, however, and learned that Goldman had been arrested with a group of activists meeting to reflect on Czolgosz. Invigorated anew by this violation of freedom of assembly, he declared, "My resurrection has come!" and set about securing their release.Berkman took the helm of Mother Earth in 1907, while Goldman toured the country to raise funds to keep it operating. Editing the magazine was a revitalizing experience for Berkman. But his relationship with Goldman faltered, and he had an affair with a 15-year-old anarchist named Becky Edelsohn. Goldman was pained by his rejection of her, but considered it a consequence of his prison experience. Later that year she served as a delegate from the US to the International Anarchist Congress of Amsterdam. Anarchists and syndicalists from around the world gathered to sort out the tension between the two ideologies, but no decisive agreement was reached. Goldman returned to the US and continued speaking to large audiences.
What did Goldman continue to do when he returned to the states?
b6b14dd759c0c14ed1a2929dfc248321532c5dbe
en
speaking to large audiences
My Disillusionment in Russia. Garden City, New York: Doubleday, Page and Co., 1923.
What state is Garden City in?
e0f81a3af3e1c5be87e6c49cd1596e87cef0d586
en
New York
On September 6, 1901, Leon Czolgosz, an unemployed factory worker and registered Republican with a history of mental illness, shot US President William McKinley twice during a public speaking event in Buffalo, New York. McKinley was hit in the breastbone and stomach, and died eight days later. Czolgosz was arrested, and interrogated around the clock. During interrogation he claimed to be an anarchist and said he had been inspired to act after attending a speech by Goldman. The authorities used this as a pretext to charge Goldman with planning McKinley's assassination. They tracked her to a residence in Chicago she shared with Hippolyte Havel, who had come to the US; as well as with Mary and Abe Isaak, an anarchist couple and their family. Goldman was arrested, along with Isaak, Havel, and ten other anarchists.
How long did the questioning go on?
1cca4efb6e037b7133166ad4b0575b8c6ce1a1ed
en
around the clock
When the Panic of 1893 struck in the following year, the United States suffered one of its worst economic crises. By year's end, the unemployment rate was higher than 20%, and "hunger demonstrations" sometimes gave way to riots. Goldman began speaking to crowds of frustrated men and women in New York City. On August 21, she spoke to a crowd of nearly 3,000 people in Union Square, where she encouraged unemployed workers to take immediate action. Her exact words are unclear: undercover agents insist she ordered the crowd to "take everything ... by force". But Goldman later recounted this message: "Well then, demonstrate before the palaces of the rich; demand work. If they do not give you work, demand bread. If they deny you both, take bread." Later in court, Detective-Sergeant Charles Jacobs offered yet another version of her speech.
In what setting did Jacobs give a different version of her speech?
4ee5a0132988f1bfa430deed9de8b762e61f02fc
en
court
Football is the most recognized and national sport of Togo. Following suit with Nigeria, Ivory Coast, Cameroon, Ghana and Senegal, Togo qualified for the World Cup in 2006. Togo did not record a win in the group stage. Togo also qualified for CAF. Bachirou Salou was the first known footballer who paved the way for all the international Togolese soccer stars. He successfully played in the German Bundesliga for more than 14 years and is a living legend for the German Clubs Borussia Mönchengladbach and MSV Duisburg, where they even perpetuated him in their stadium. Salou gained 38 caps for Togo during a nine-year span. He played 300 games and scored 69 goals in the German major league.
Among sports, which is the most popular in Togo?
79b5e438cf9970ff2a780b0916e95445395b4c5d
en
Football
In 1884, a paper was signed at Togoville with the King Mlapa III, whereby Germany claimed a protectorate over a stretch of territory along the coast and gradually extended its control inland. Its borders were defined after the capture of hinterland by German forces and signing agreements with France and Britain. In 1905, this became the German colony of Togoland. The local population was forced to work, cultivate cotton, coffee and cocoa and pay high taxes. A railway and the port of Lomé were built for export of agricultural products. The Germans introduced modern techniques of cultivation of cocoa, coffee and cotton and developed the infrastructure.
When were the papers signed?
8aea9849a965404be025d13314cd117fc68af66f
en
1884
The highest mountain of the country is the Mont Agou at 986 m above sea level. The longest river is the Mono River with a length of 400 km. It runs from north to south.
How long was the Mono River?
688e43ec163fbc06b9d8f65d221f7c8484b34266
en
400 km
Togo ( (listen)), officially the Togolese Republic (French: République togolaise), is a country in West Africa bordered by Ghana to the west, Benin to the east and Burkina Faso to the north. The sovereign state extends south to the Gulf of Guinea, where its capital Lomé is located. Togo covers 57,000 square kilometres (22,008 square miles), making it one of the smallest countries in Africa, with a population of approximately 7.6 million.From the 11th to the 16th century, various tribes entered the region from all directions. From the 16th century to the 18th century, the coastal region was a major trading center for Europeans to purchase slaves, earning Togo and the surrounding region the name "The Slave Coast". In 1884, Germany declared a region including present-day Togo as a protectorate called Togoland. After World War I, rule over Togo was transferred to France. Togo gained its independence from France in 1960. In 1967, Gnassingbé Eyadéma led a successful military coup d'état after which he became president of an anti-communist, single-party state. Eventually, in 1993, Eyadéma faced multiparty elections, which were marred by irregularities, and won the presidency three times. At the time of his death, Eyadéma was the longest-serving leader in modern African history, having been president for 38 years. In 2005, his son Faure Gnassingbé was elected president.
Who was elected president in 2005?
9c923c953103d22707977a66944dc8c05a8d5d05
en
Faure Gnassingbé
Togo is a multilingual country. According to Ethnologue, 39 distinct languages are spoken in the country, many of them by communities that number fewer than 100,000 members. Of the 39 languages, the sole official language is French. Two spoken indigenous languages were designated politically as national languages in 1975: Ewé (Ewe: Èʋegbe; French: Evé) and Kabiyé; they are also the two most widely spoken indigenous languages.
What is the official language of Togo?
54829eb557b438847b789dd6d964120dec6aa59b
en
French
Togo is a tropical, sub-Saharan nation, whose economy depends highly on agriculture, with a climate that provides good growing seasons. While the official language is French, many other languages are spoken in Togo, particularly those of the Gbe family. The largest religious group in Togo consists of those with indigenous beliefs, and there are significant Christian and Muslim minorities. Togo is a member of the United Nations, African Union, Organisation of Islamic Cooperation, South Atlantic Peace and Cooperation Zone, Francophonie, and Economic Community of West African States.
Which African community is Togo a member of?
618d5856b7832ac85d75c9348c6fd088565d32d6
en
Economic Community of West African States
A brief lull in hostilities allowed Pitt to concentrate effort on Ireland, where there had been an uprising and attempted French landing in 1798. In 1800, the British and Irish Parliaments passed an Act of Union that took effect on 1 January 1801 and united Great Britain and Ireland into a single state, known as the "United Kingdom of Great Britain and Ireland". George used the opportunity to abandon the title "king of France", which English and British Sovereigns had maintained since the reign of Edward III. It was suggested that George adopt the title "Emperor of the British Isles", but he refused. As part of his Irish policy, Pitt planned to remove certain legal disabilities that applied to Roman Catholics. George III claimed that to emancipate Catholics would be to violate his coronation oath, in which Sovereigns promise to maintain Protestantism. Faced with opposition to his religious reform policies from both the King and the British public, Pitt threatened to resign. At about the same time, the King had a relapse of his previous illness, which he blamed on worry over the Catholic question. On 14 March 1801, Pitt was formally replaced by the Speaker of the House of Commons, Henry Addington. Addington opposed emancipation, instituted annual accounts, abolished income tax and began a programme of disarmament. In October 1801, he made peace with the French, and in 1802 signed the Treaty of Amiens.George did not consider the peace with France as real; in his view it was an "experiment". In 1803, the war resumed but public opinion distrusted Addington to lead the nation in war, and instead favoured Pitt. An invasion of England by Napoleon seemed imminent, and a massive volunteer movement arose to defend England against the French. George's review of 27,000 volunteers in Hyde Park, London, on 26 and 28 October 1803 and at the height of the invasion scare, attracted an estimated 500,000 spectators on each day. The Times said, "The enthusiasm of the multitude was beyond all expression." A courtier wrote on 13 November that, "The King is really prepared to take the field in case of attack, his beds are ready and he can move at half an hour's warning." George wrote to his friend Bishop Hurd, "We are here in daily expectation that Bonaparte will attempt his threatened invasion ... Should his troops effect a landing, I shall certainly put myself at the head of mine, and my other armed subjects, to repel them." After Admiral Lord Nelson's famous naval victory at the Battle of Trafalgar, the possibility of invasion was extinguished.
In what year was a French landing attempted?
169ff8b2456a4d165c273d723b656cea5d9d46cb
en
1798
A brief lull in hostilities allowed Pitt to concentrate effort on Ireland, where there had been an uprising and attempted French landing in 1798. In 1800, the British and Irish Parliaments passed an Act of Union that took effect on 1 January 1801 and united Great Britain and Ireland into a single state, known as the "United Kingdom of Great Britain and Ireland". George used the opportunity to abandon the title "king of France", which English and British Sovereigns had maintained since the reign of Edward III. It was suggested that George adopt the title "Emperor of the British Isles", but he refused. As part of his Irish policy, Pitt planned to remove certain legal disabilities that applied to Roman Catholics. George III claimed that to emancipate Catholics would be to violate his coronation oath, in which Sovereigns promise to maintain Protestantism. Faced with opposition to his religious reform policies from both the King and the British public, Pitt threatened to resign. At about the same time, the King had a relapse of his previous illness, which he blamed on worry over the Catholic question. On 14 March 1801, Pitt was formally replaced by the Speaker of the House of Commons, Henry Addington. Addington opposed emancipation, instituted annual accounts, abolished income tax and began a programme of disarmament. In October 1801, he made peace with the French, and in 1802 signed the Treaty of Amiens.George did not consider the peace with France as real; in his view it was an "experiment". In 1803, the war resumed but public opinion distrusted Addington to lead the nation in war, and instead favoured Pitt. An invasion of England by Napoleon seemed imminent, and a massive volunteer movement arose to defend England against the French. George's review of 27,000 volunteers in Hyde Park, London, on 26 and 28 October 1803 and at the height of the invasion scare, attracted an estimated 500,000 spectators on each day. The Times said, "The enthusiasm of the multitude was beyond all expression." A courtier wrote on 13 November that, "The King is really prepared to take the field in case of attack, his beds are ready and he can move at half an hour's warning." George wrote to his friend Bishop Hurd, "We are here in daily expectation that Bonaparte will attempt his threatened invasion ... Should his troops effect a landing, I shall certainly put myself at the head of mine, and my other armed subjects, to repel them." After Admiral Lord Nelson's famous naval victory at the Battle of Trafalgar, the possibility of invasion was extinguished.
How many visitors did George's review bring in to Hyde Park per day?
eeac1e063d31fd5cf51a31c9f80fdfb2bfbf4b3f
en
500,000
For George III, Pitt's appointment was a great victory. It proved that he was able to appoint Prime Ministers on the basis of his own interpretation of the public mood without having to follow the choice of the current majority in the House of Commons. Throughout Pitt's ministry, George supported many of Pitt's political aims and created new peers at an unprecedented rate to increase the number of Pitt's supporters in the House of Lords. During and after Pitt's ministry, George III was extremely popular in Britain. The British people admired him for his piety, and for remaining faithful to his wife. He was fond of his children, and was devastated at the death of two of his sons in infancy in 1782 and 1783 respectively. Nevertheless, he set his children a strict regimen. They were expected to attend rigorous lessons from seven in the morning, and to lead lives of religious observance and virtue. When his children strayed from George's own principles of righteousness, as his sons did as young adults, he was dismayed and disappointed.By this time George's health was deteriorating. He had a mental illness, characterised by acute mania, which was possibly a symptom of the genetic disease porphyria, although this has been questioned. A study of samples of the King's hair published in 2005 revealed high levels of arsenic, a possible trigger for the disease. The source of the arsenic is not known, but it could have been a component of medicines or cosmetics. The King may have had a brief episode of disease in 1765, but a longer episode began in the summer of 1788. At the end of the parliamentary session, he went to Cheltenham Spa to recuperate. It was the furthest he had ever been from London—just short of 100 miles (150 km)—but his condition worsened. In November he became seriously deranged, sometimes speaking for many hours without pause, causing him to foam at the mouth and making his voice hoarse. George would frequently repeat himself, and write sentences with over 400 words at a time, as well as his vocabulary becoming more complex, possible symptoms of bipolar disorder. His doctors were largely at a loss to explain his illness, and spurious stories about his condition spread, such as the claim that he shook hands with a tree in the mistaken belief that it was the King of Prussia. Treatment for mental illness was primitive by modern standards, and the King's doctors, who included Francis Willis, treated the King by forcibly restraining him until he was calm, or applying caustic poultices to draw out "evil humours".In the reconvened Parliament, Fox and Pitt wrangled over the terms of a regency during the King's incapacity. While both agreed that it would be most reasonable for George III's eldest son and heir apparent, the Prince of Wales, to act as regent, to Pitt's consternation Fox suggested that it was the Prince of Wales's absolute right to act on his ill father's behalf with full powers. Pitt, fearing he would be removed from office if the Prince of Wales were empowered, argued that it was for Parliament to nominate a regent, and wanted to restrict the regent's authority. In February 1789, the Regency Bill, authorising the Prince of Wales to act as regent, was introduced and passed in the House of Commons, but before the House of Lords could pass the bill, George III recovered.
To whom was the appointment of Pitt was a great victory?
50e74daebc87e9791b5171d1e1a8eb78dba819be
en
George III
For George III, Pitt's appointment was a great victory. It proved that he was able to appoint Prime Ministers on the basis of his own interpretation of the public mood without having to follow the choice of the current majority in the House of Commons. Throughout Pitt's ministry, George supported many of Pitt's political aims and created new peers at an unprecedented rate to increase the number of Pitt's supporters in the House of Lords. During and after Pitt's ministry, George III was extremely popular in Britain. The British people admired him for his piety, and for remaining faithful to his wife. He was fond of his children, and was devastated at the death of two of his sons in infancy in 1782 and 1783 respectively. Nevertheless, he set his children a strict regimen. They were expected to attend rigorous lessons from seven in the morning, and to lead lives of religious observance and virtue. When his children strayed from George's own principles of righteousness, as his sons did as young adults, he was dismayed and disappointed.By this time George's health was deteriorating. He had a mental illness, characterised by acute mania, which was possibly a symptom of the genetic disease porphyria, although this has been questioned. A study of samples of the King's hair published in 2005 revealed high levels of arsenic, a possible trigger for the disease. The source of the arsenic is not known, but it could have been a component of medicines or cosmetics. The King may have had a brief episode of disease in 1765, but a longer episode began in the summer of 1788. At the end of the parliamentary session, he went to Cheltenham Spa to recuperate. It was the furthest he had ever been from London—just short of 100 miles (150 km)—but his condition worsened. In November he became seriously deranged, sometimes speaking for many hours without pause, causing him to foam at the mouth and making his voice hoarse. George would frequently repeat himself, and write sentences with over 400 words at a time, as well as his vocabulary becoming more complex, possible symptoms of bipolar disorder. His doctors were largely at a loss to explain his illness, and spurious stories about his condition spread, such as the claim that he shook hands with a tree in the mistaken belief that it was the King of Prussia. Treatment for mental illness was primitive by modern standards, and the King's doctors, who included Francis Willis, treated the King by forcibly restraining him until he was calm, or applying caustic poultices to draw out "evil humours".In the reconvened Parliament, Fox and Pitt wrangled over the terms of a regency during the King's incapacity. While both agreed that it would be most reasonable for George III's eldest son and heir apparent, the Prince of Wales, to act as regent, to Pitt's consternation Fox suggested that it was the Prince of Wales's absolute right to act on his ill father's behalf with full powers. Pitt, fearing he would be removed from office if the Prince of Wales were empowered, argued that it was for Parliament to nominate a regent, and wanted to restrict the regent's authority. In February 1789, the Regency Bill, authorising the Prince of Wales to act as regent, was introduced and passed in the House of Commons, but before the House of Lords could pass the bill, George III recovered.
Did his condition improve?
f1a7cf54502bf3d49c90dbac794ee91033703a6f
en
his condition worsened
George III hoped that "the tongue of malice may not paint my intentions in those colours she admires, nor the sycophant extoll me beyond what I deserve", but in the popular mind George III has been both demonised and praised. While very popular at the start of his reign, by the mid-1770s George had lost the loyalty of revolutionary American colonists, though it has been estimated that as many as half of the colonists remained loyal. The grievances in the United States Declaration of Independence were presented as "repeated injuries and usurpations" that he had committed to establish an "absolute Tyranny" over the colonies. The Declaration's wording has contributed to the American public's perception of George as a tyrant. Contemporary accounts of George III's life fall into two camps: one demonstrating "attitudes dominant in the latter part of the reign, when the King had become a revered symbol of national resistance to French ideas and French power", while the other "derived their views of the King from the bitter partisan strife of the first two decades of the reign, and they expressed in their works the views of the opposition".Building on the latter of these two assessments, British historians of the nineteenth and early twentieth centuries, such as Trevelyan and Erskine May, promoted hostile interpretations of George III's life. However, in the mid-twentieth century the work of Lewis Namier, who thought George was "much maligned", started a re-evaluation of the man and his reign. Scholars of the later twentieth century, such as Butterfield and Pares, and Macalpine and Hunter, are inclined to treat George sympathetically, seeing him as a victim of circumstance and illness. Butterfield rejected the arguments of his Victorian predecessors with withering disdain: "Erskine May must be a good example of the way in which an historian may fall into error through an excess of brilliance. His capacity for synthesis, and his ability to dovetail the various parts of the evidence ... carried him into a more profound and complicated elaboration of error than some of his more pedestrian predecessors ... he inserted a doctrinal element into his history which, granted his original aberrations, was calculated to project the lines of his error, carrying his work still further from centrality or truth." In pursuing war with the American colonists, George III believed he was defending the right of an elected Parliament to levy taxes, rather than seeking to expand his own power or prerogatives. In the opinion of modern scholars, during the long reign of George III the monarchy continued to lose its political power, and grew as the embodiment of national morality.
What was King George III accused of in the Declaration of Independence?
7580a3eaa676b82877e6983971607c17ebc91f8b
en
absolute Tyranny