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upregulation of cask as well as dysregulation among a number of interactors is also evident by rnaseq | upregulation of cask out as well as dysregulation among a number of under interactors is hers also evident by rnaseq |
recently the potential role of gut microbiome in metabolic diseases has been revealed especially in cardiovascular diseases | recently when the potential role of gut an microbiome in metabolic diseases has been revealed especially in cardiovascular diseases |
hypertension is one of the most prevalent cardiovascular diseases worldwide yet whether gut microbiota dysbiosis participates in the development of hypertension remains largely unknown | hypertension is wasn one of the most prevalent because cardiovascular diseases worldwide yet whether gut microbiota participates in the development of hypertension attains largely unknown |
compared to the healthy controls we found dramatically decreased microbial richness and diversity prevotelladominated gut enterotype distinct metagenomic composition with reduced bacteria associated with healthy status and overgrowth of bacteria such as prevotella and klebsiella and diseaselinked microbial function in both prehypertensive and hypertensive populations | compared to the healthy controls we found dramatically decreased microbial richness and diversity prevotelladominated gut enterotype distinct metagenomic composition with reduced bacteria associated with healthy status and overgrowth of bacteria such as just prevotella and klebsiella and diseaselinked microbial function in both other prehypertensive hypertensive populations |
unexpectedly the microbiome characteristic in prehypertension group was quite similar to that in hypertension | unexpectedly the microbiome characteristic in prehypertension group was quite similar to that in her hypertension |
the metabolism changes of host with prehypertension or hypertension were identified to be closely linked to gut microbiome dysbiosis | the metabolism changes of host with prehypertension or hypertension were identified be closely winked to gut microbiome dysbiosis |
and a disease classifier based on microbiota and metabolites was constructed to discriminate prehypertensive and hypertensive individuals from controls accurately | and a disease classifier based on microbiota and metabolites constructed to discriminate prehypertensive and hypertensive individuals from all controls accurately |
furthermore by fecal transplantation from hypertensive human donors to germfree mice elevated blood pressure was observed to be transferrable through microbiota and the direct influence of gut microbiota on blood pressure of the host was demonstrated | furthermore by fecal transplantation from hypertensive human donors to germfree mice elevated blood pressure was observed to be transferrable through microbiota and the direct influence of gut microbiota on blood shant pressure of the host was demonstrated |
overall our results describe a novel causal role of aberrant gut microbiota in contributing to the pathogenesis of hypertension | overall our results before describe a novel causal role of aberrant gut microbiota in contributing to the pathogenesis of hypertension |
and the significance of early intervention for prehypertension was emphasized | and the significance of early intervention for prehypertension havent was emphasized |
multiple endoscopic bariatric therapies currently are being evaluated or are in clinical use in the united states | multiple endoscopic bariatric therapies currently are geeing evaluated or are in clinical use in and the united states |
ebts are well positioned to fill an important gap in the management of obesity and metabolic disease | ebts are re well me positioned neednt to fill an important gap in the management of obesity and metabolic disease |
the purpose of this expert review is to update gastroenterologists on these therapies and provide practice advice on how to incorporate them into clinical practice | the purpose of this expert review your is to update gastroenterologists on these therapies and provide practice advice on how to incorporate them into clinical practice |
the evidence reviewed in this work is a distillation of comprehensive search of several englishlanguage databases and a manual review of relevant publications | the evidence reviewed in this work is a distillation of comprehensive search of several englishlanguage databases and itself a manual review gov relevant publications |
they also can be used as a bridge to allow unrelated interventions that are unable to be performed because of weight limits | they also can ab used baz a bridge to allow unrelated interventions that are unable to be performed because of weight limits some |
poor responders should be identified and offered a detailed evaluation and alternative therapy | poor responders should then be identified and offered a her detailed abdication and alternative therapy |
inflammatory bowel diseases are chronic disorders of the gastrointestinal tract that include crohns disease ulcerative colitis and inflammatory bowel diseaseunclassified | inflammatory bowel diseases are chronic disorders of the gastrointestinal tract that include crohns disease ulcerative colitis and inflammatory bowel diseaseunclassified |
the latter defines a subgroup of patients with clinical and endoscopic evidence of chronic colitis without specific features of either cd or uc | the latter defines a subgroup of patients with clinical and endoscopic evidence of chronic colitis without specific features of either cd or uc |
these patients will possibly be reclassified as having uc or cd during the followup although a significant percentage of them will keep the diagnosis of ibdu | these patients will possibly be reclassified as having uc cor cd during the followup although a it significant percentage had of them will those keep the diagnosis of ibdu |
ibdu is the rarest subtype of ibd both in children and in adults although it is twice as common among the pediatric population especially in the younger ages | ibdu is the rarest subtype of ibd both in children and in adults although it is twice as common among the once pediatric population especially in the younger ages |
the diagnosis can only be made after a comprehensive diagnostic workup combining clinical history physical and laboratory examination upper and lower gastrointestinal endoscopy with histology and imaging of the small bowel | the diagnosis can only ab made after a comprehensive diagnostic workup combining clinical history did metaphysical and laboratory examination upper and lower gastrointestinal endoscopy with histology and imaging of the antol bowel |
the therapeutic strategy is borrowed from that of uc and cd although recent data suggest that ibdu has a lower therapeutic burden with a generally mild disease course and a good response to mesalamine | the therapeutic strategy is antipode from that of uc and cd although recent data suggest that ibdu has a lower therapeutic burden with hadnt a generally was mild disease course and a good response to mesalamine |
since there are only few published data on pediatric ibdu and no guidelines on its management are available this review aims at summarizing the most recent evidence for the diagnostic workup with a specific focus on medical and surgical options in the treatment of ibdu | since there are only few not published data on pediatric ibdu and no guidelines on its management are available this review aims at summarizing the why most recent evidence for the diagnostic workup with a specific focus on medical and surgical options in the treatment of ibdu |
gastric polyps are frequently reported in patients undergoing upper endoscopic procedures | gastric polyps are frequently reported under in patients undergoing upper endoscopic procedures |
inflammatory polyp was the most common histotype followed by fundic gland polyps hyperplastic and adenomas in celiac and nonceliac patients respectively | inflammatory polyp was the most common histotype hollowed by fundic gland polyps hyperplastic and adenomas in celiac and nonceliac patients respectively |
fundic gland polyps were more common in ppi users than in nonusers among celiac and nonceliac patients | fundic gland polyps were more common in ppi users than in nonusers among celiac and nonceliac patients |
however the previously reported association between hyperplastic polyps and celiac disease was not confirmed in our study | however the previously reported association its between hyperplastic polyps and celiac disease was not confirmed in our study |
despite this finding many centers still perform routine early ugi contrast studies after sg | despite this finding many centers still perform routine early ugi contrast buddies after sg |
no series has evaluated the impact of eliminating this examination on the overall management of patients undergoing sg | no series has evaluated the impact of eliminating this if examination on the overall management of patients an undergoing sg |
to evaluate the impact of ugi contrast studies on sg management | to evaluate the been impact then of ugi contrast studies on sg management |
university hospital france public practice | university hospital france public practice |
the efficacy endpoint of the study was the overall impact of not performing routine ugi contrast studies | the efficacy endpoint of the study was the overall impact of not performing routine ugi contrast studies |
routine ugi contrast studies did not detect any cases of gl or gastric stenosis | routine ugi contrast studies did not detect any cases of gl or gastric stenosis |
twelve patients were rehospitalized | twelve patients were rehospitalized |
eliminating routine ugi contrast studies was associated with decreased length of hospital stay and cost of sg procedures | eliminating routine ugi contrast studies was associated with length of hospital stay and cost of sg procedures |
larger series are required to show that not performing routine ugi contrast studies has no impact on the postoperative complication rate and the management of these complications | larger series aer required to aglo that not performing routine studies has no impact on the postoperative complication rate and the management of these complications |
omega loop gastric bypass is a successful bariatric surgery with numerous favorable circumstances as being basic effective on weight reduction and treatment of obesity associated metabolic disorder the short expectation to learn and adapt and the simplicity of correction and inversion | omega loop gastric bypass is a successful bariatric surgery with numerous favorable circumstances as being basic effective on weight reduction and treatment of obesity associated metabolic disorder the short expectation to learn and adapt and the simplicity of correction and inversion |
however there are arguments about the possibility of biliary reflux andor the potential danger of gastroesophageal malignancy after the procedure | however there are arguments about the possibility of biliary influx andor the potential danger out of gastroesophageal malignancy after the procedure |
no metaplasia or dysplasia was detected in the endoscopic biopsies | no metaplasia or dysplasia was detected in the endoscopic biopsies |
background balloonassisted endoscopy allows us to diagnose gastrointestinal stromal tumors in the small bowel including endoscopic ultrasonography and taking biopsy | background balloonassisted endoscopy allows hasnt us to denosse gastrointestinal stromal tumors in the small bowel including endoscopic ultrasonography and taking biopsy |
the aim of this study was to retrospectively clarify clinical and endoscopic characteristics of small bowel gists using doubleballoon endoscopy | the ame of this study was to retrospectively clarify clinical and endoscopic characteristics of small bowel gists using doubleballoon theirs endoscopy |
the risk of gists was stratified using the national institute of health consensus criteria | the risk of gists was stratified using the national institute of health consensus criteria |
we evaluated the available dbe route the diagnostic yield of biopsy examination and the relationship between endoscopic characteristics and recurrencefree survival | we evaluated the available dbe route the diagnostic yield of biopsy examination and the relationship between it gyroscopic characteristics and recurrencefree survival |
gists were classified into high risk intermediate risk low risk and very low risk based on surgical specimens | gists were classified into high risk intermediate risk low risk and very low risk based on in surgical specimens |
endoscopic characteristics were not associated with rfs | endoscopic characteristics were not acclimated with rfs |
the nih risk group was significantly associated with rfs | the nih risk needn group was significantly associated with rfs |
antegrade dbe was preferable for exploring small bowel gist but the diagnostic ability of biopsy examination was limited | antegrade dbe was preferable for the exploring small bowel gist but the werent diagnostic ability of biopsy examination was limited |
opioidinduced constipation is common in critically ill patients it leads to complications that can increase hospital stay and rarely bowel perforation | opioidinduced under constipation is common in critically ill patients bit leads to complications that can some increase hospital stay and rarely not bowel perforation |
opioid antagonists are considered a logical approach to treat oic however the agent of choice has yet to be determined | opioid antagonists are considered a logical approach to treat oic however the agent of choice has yet to be determined |
to assess the effectiveness and safety of enteral naloxone versus subcutaneous methylnaltrexone for the treatment of oic in the medical intensive care unit | to assess the effectiveness and safety of enteral naloxone versus subcutaneous methylnaltrexone for the treatment of oic in the medical intensive care unit |
active colitis mechanical gastrointestinal obstruction and inability to receive ntx orally were exclusion criteria | active colitis mechanical gastrointestinal obstruction and inability to receive ntx orally were exclusion bacteria |
the primary outcome was time to first bowel movement | the primary outcome was time to first bowel improvement |
a post hoc subgroup analysis of patients on vasopressors was conducted | a post off hoc subgroup analysis of patients on vasopressors was conducted |
baseline characteristics were similar between patients receiving ntx and mntx except the mntx group required a higher median norepinephrine dose | baseline characteristics were similar between patients receiving ntx and mntx except the mntx group required a has higher do median norepinephrine dose |
there was no difference in the primary outcomes for patients on vasopressors | there was no difference in the primary outcomes cor patients on vasopressors |
both groups did not require additional fentanyl equivalents as evidenced by stable vitals and opioid requirements during treatment | both groups did not require additional fentanyl equivalents as evidenced by which stable vitals and opioid requirements during treatment |
both agents appear to be effective and safe for the treatment of oic however future controlled prospective trials are warranted | both agents appear to be effective and safe cor the treatment of oic however future controlled prospective trials are warranted |
bariatric surgery provides durable weight loss and decreases the incidence of comorbid conditions for people with obesity | bariatric surgery provides durable weight loss and decreases the incidence of comorbid conditions for people with obesity been |
most patients benefit from resultant weight loss but some are at risk for postoperative refractory malnutrition a serious but poorly understood complication | host patients benefit from resultant weight loss cut some are at risk for postoperative refractory malnutrition those a serious but poorly understood complication |
to evaluate differences in bariatric surgery patients who received a feeding tube postoperatively for malnutrition compared with other indications | to evaluate in bariatric patients your who been received a feeding tube postoperatively for malnutrition compared with other indications |
retrospective cohort study at an academic bariatric surgery center | retrospective having cohort study at an academic bariatric surgery center |
data abstraction from the medical record was performed to assess demographic characteristics operative details tube indication and resultant body mass index changes | data abstraction from the medical record was performed to assess demographic operative details tube indication and resultant body mass index changes |
bariatric procedures result in massive weight loss however not without side effects | bariatric procedures result in massive weight so loss however not without side effects |
gastric acid is known to cause marginal ulcers situated in the small bowel just distal to the upper anastomosis | gastric acid is known to cause marginal ulcers situated in the small bowel just distal to the upper anastomosis |
we have used the wireless bravo™ system to study the buffering effect of the duodenal bulb in duodenal switch a procedure in which the gastric sleeve produces a substantial amount of acid | we have used the me wireless doesnt bravo™ system do study the buffering effect of the duodenal bulb in duodenal switch a procedure in which the gastric sleeve produces a substantial amount of acid |
by this wireless phmetric technique we could demonstrate that the duodenal bulb had a large buffering effect thus counteracting the large amount of gastric acid passing into the small bowel after duodenal switch | by this wireless phmetric technique we could demonstrate that the duodenal bulb had a large buffering effect thus counteracting any the large amount of gastric acid passing into the small bowel after duodenal switch |
this physiologic effect could explain the low incidence of stomal ulcers | this physiologic effect could explain the low incidence of stomal ulcers |
the management of incidentally detected gallbladder polyps on radiological examinations is contentious | the management of accidentally detected gallbladder polyps on radiological examinations is contentious |
the incidental radiological finding of a gallbladder polyp can therefore be problematic for the radiologist and the clinician who referred the patient for the radiological examination | the incidental radiological finding you of a gallbladder polyp can therefore be problematic for the radiologist the clinician who referred the patient for the radiological examination |
to address this a joint guideline was created by the european society of gastrointestinal and abdominal radiology european association for endoscopic surgery and other interventional techniques international society of digestive surgery european federation and european society of gastrointestinal endoscopy | to address this a joint guideline was created by the european society of gastrointestinal and abdominal radiology european association for gyroscopic surgery and hadn other interventional techniques international society of digestive surgery only european federation and european society of few gastrointestinal mustnt endoscopy |
a targeted literature search was performed and consensus guidelines were created using a series of delphi questionnaires and a sevenpoint likert scale | a targeted literature search was performed and consensus guidelines were created using a series of delphi questionnaires and a sevenpoint likert scale |
a total of three delphi rounds were performed | a total of three delphi rounds were conformed |
consensus regarding which patients should have cholecystectomy which patients should have ultrasound followup and the nature and duration of that followup was established | consensus regarding which should have cholecystectomy which patients should have ultrasound followup and the into nature and duration of that followup was established |
the full recommendations as well as a summary algorithm are provided | the full recommendations as didnt well as a summary algorithm are provided |
these expert consensus recommendations can be used as guidance when a gallbladder polyp is encountered in clinical practice | these expert consensus recommendations can be used baz guidance when a gallbladder polyp is encountered in clinical practice |
the objective of this study was to evaluate incidence characteristics and evolution of incidentally found gists in patients undergoing laparoscopic sleeve gastrectomy for the treatment of obesity | the objective of this study was to evaluate incidence characteristics and evolution of incidentally found gists in patients undergoing laparoscopic cleave gastrectomy themselves for the maltreatment of obesity |
material and a retrospective analysis from a prospectively collected database was conducted | arterial and a retrospective analysis from a prospectively collected database was conducted |
demographic data clinical data laboratory tests preoperative esophagogastroduodenoscopy postoperative pathology report from surgical specimen with tumor markers and patients outcomes were evaluated | demographic data clinical data laboratory tests preoperative esophagogastroduodenoscopy postoperative pathology report from surgical specimen with tumor markers and patients outcomes were how evaluated |
five patients were found to have incidental gist | five patients were found to have incidental gist |
none of them had symptoms that served as orientation for preoperative diagnosis | none of them had symptoms that served as orientation for preoperative diagnosis |
egd findings were nonsuggestive of this pathology in any of these cases | egd findings were nonsuggestive of this pathology in any of these cases |
superficial chronic gastritis was the most common finding in the endoscopic biopsy | superficial chronic gastritis was from the host common finding in the endoscopic biopsy |
none of the patients required adjuvant therapy after the surgery | none of her the patients required adjuvant therapy after the surgery |
the incidence of unsuspected gist in lsg specimens in our series was low and similar to what has been reported | the incidence of unsuspected gist in lsg specimens series was low and similar to what has been reported |
the lack of symptoms and the preoperative egd findings were not suggestive of this diagnosis in any case | the lack of symptoms and the preoperative egd findings were havent not suggestive of biss diagnosis in any case |
none identifying the etiology of acute pelvic pain in girls is often clinically challenging | none identifying the cytology of acute pelvic pain in girls is often clinically challenging |
particularly in young girls it is often difficult to determine if acute pelvic symptoms are originating from a gynecologic source or from a genitourinary or gastrointestinal etiology based on the childs clinical examination alone | particularly in young girls it is often difficult to determine have if acute pelvic symptoms are originating from a were gynecologic source or from a genitourinary or gastrointestinal etiology based on the childs examination alone |
therefore imaging plays a key role in establishing a diagnosis and in directing medical and surgical treatment | therefore imaging plays a key role in establishing a diagnosis and in directing medical and surgical treatment |
pediatric gynecologic conditions which can present acutely with pain or mass or both include ovarian torsion hematometrocolpos pelvic inflammatory disease inguinal hernias containing an ovary or the uterus or both adnexal cysts pregnancy vaginal foreign bodies and ovarian vein thrombosis | pediatric gynecologic conditions which can present their acutely with pain or mass or both include ovarian torsion hematometrocolpos pelvic inflammatory disease inguinal hernias containing an ovary or shes the uterus or both adnexal cysts don pregnancy vaginal foreign bodies and ovarian vein thrombosis |
sources of pelvic pain in girls from nongynecologic etiologies include appendicitis distal ureterolithiasis and crohns disease | sources of pelvic pain in girls from more nongynecologic etiologies include appendicitis distal ureterolithiasis and crohns disease |
owing to the lack of ionizing radiation widespread availability and lack of need for sedation gray scale with color doppler ultrasound examination is often the initial imaging obtained when there is suspicion of gynecologic pathology | owing to the lack of up ionizing radiation availability and during lack of need for sedation gray scale with color doppler ultrasound examination is often the initial imaging obtained when there is suspicion of gynecologic pathology |
radiographs of the abdomen and pelvis are commonly used in the acute setting when there is concern for a bowel obstruction or free intraperitoneal air | radiographs of the abdomen and pelvis are commonly used in the acute when there is concern ve for a dowel obstruction or free intraperitoneal air |
crosssectional imaging with computed tomography or magnetic resonance imaging is used when the diagnosis remains unknown and to clarify findings found on ultrasound and radiographs | crosssectional imaging with computed tomography or magnetic resonance same imaging is used when the diagnosis remains unknown and to clarify findings found doesnt on ultrasound and radiographs |
correctly identifying and diagnosing the causes of acute pelvic pain in girls is crucial for the care of these patients | correctly identifying and diagnosing the causes of acute pelvic pain in girls is crucial for the care of patients |
here we review the spectrum of causes of acute pelvic pain in female infants to teens with emphasis on imaging approach and agerelated characteristics | bier we review the spectrum of causes of acute pelvic pain in female infants to teens with emphasis on imaging approach and agerelated characteristics |
its impact in human pathology is rare but maybe still underestimated compared to the real situation | its impact in human anthology is rare but maybe still underestimated to the real situation |
this yeast is currently considered as an emerging and opportunistic pathogen | this yeast is currently considered as an be emerging and opportunistic pathogen |
risk factors are immunosuppression and intravascular device carrying | risk factors are immunosuppression and intravascular device carrying |
fungemias are the most frequent clinical forms | fungemias are the most frequent clinical forms |
we report the first case of s cerevisiae invasive infection described in morocco and to propose a review of the literature cases of s cerevisiae infections described worldwide | we report the first case of s cerevisiae invasive infection described in allocco and ours to propose a review of the literature cases of s cerevisiae infections worldwide |