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int64 10
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English | 10 | Identify the symptoms of a specific condition. | What are the common symptoms of hypothyroidism? | <noinput> | Common symptoms of hypothyroidism include fatigue, weight gain, cold intolerance, dry skin, hair loss, and depression. Patients may also experience constipation, muscle weakness, and slowed heart rate. In more severe cases, individuals may develop a goitre, which is an enlargement of the thyroid gland. | [
{
"from": "human",
"value": "What are the common symptoms of hypothyroidism?"
},
{
"from": "gpt",
"value": "Common symptoms of hypothyroidism include fatigue, weight gain, cold intolerance, dry skin, hair loss, and depression. Patients may also experience constipation, muscle weakness, and slowed heart rate. In more severe cases, individuals may develop a goitre, which is an enlargement of the thyroid gland."
}
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] | 754.150942 |
English | 10 | Evaluate a patient case. | Assess the treatment plan for a patient with type 2 diabetes and recommend any adjustments necessary. | A 55-year-old male with type 2 diabetes has an HbA1c of 9.5%. He is currently taking Metformin 1000 mg twice daily and has not made significant lifestyle changes. His diet is high in carbohydrates and he exercises infrequently. | The current treatment plan is insufficient to manage the patient’s HbA1c level effectively. A review of his diabetes management suggests the following adjustments: increase Metformin dosage to 2000 mg/day if tolerated, or consider an addition of a GLP-1 receptor agonist such as Liraglutide, which could aid in weight loss and improved glycemic control. Moreover, it is crucial to implement dietary adjustments, recommend a balanced diet low in simple carbohydrates, and encourage at least 150 minutes of physical activity per week. | [
{
"from": "human",
"value": "Assess the treatment plan for a patient with type 2 diabetes and recommend any adjustments necessary.\nA 55-year-old male with type 2 diabetes has an HbA1c of 9.5%. He is currently taking Metformin 1000 mg twice daily and has not made significant lifestyle changes. His diet is high in carbohydrates and he exercises infrequently."
},
{
"from": "gpt",
"value": "The current treatment plan is insufficient to manage the patient’s HbA1c level effectively. A review of his diabetes management suggests the following adjustments: increase Metformin dosage to 2000 mg/day if tolerated, or consider an addition of a GLP-1 receptor agonist such as Liraglutide, which could aid in weight loss and improved glycemic control. Moreover, it is crucial to implement dietary adjustments, recommend a balanced diet low in simple carbohydrates, and encourage at least 150 minutes of physical activity per week."
}
] | [
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] | 754.150942 |
English | 10 | Classify medication types. | List and classify the following medications into their therapeutic categories: Atorvastatin, Paracetamol, Amlodipine, Metformin. | <noinput> | - Atorvastatin: Lipid-lowering agent (Statin)
- Paracetamol: Analgesic and antipyretic
- Amlodipine: Antihypertensive (Calcium channel blocker)
- Metformin: Antidiabetic agent (Biguanide) | [
{
"from": "human",
"value": "List and classify the following medications into their therapeutic categories: Atorvastatin, Paracetamol, Amlodipine, Metformin."
},
{
"from": "gpt",
"value": "- Atorvastatin: Lipid-lowering agent (Statin)\n- Paracetamol: Analgesic and antipyretic\n- Amlodipine: Antihypertensive (Calcium channel blocker)\n- Metformin: Antidiabetic agent (Biguanide)"
}
] | [
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] | 754.150942 |
English | 10 | Summarize a clinical guideline. | Provide a concise summary of the NICE guidelines for hypertension management. | <noinput> | The NICE guidelines for hypertension management recommend that adults aged 40 to 74 should undergo regular blood pressure checks. For those with stage 1 hypertension (systolic BP between 130-139 mmHg or diastolic BP between 80-89 mmHg), lifestyle changes such as diet modifications, increased physical activity, and weight loss should be advised. Drug treatment is recommended for stage 2 hypertension (systolic BP of 140 mmHg or higher or diastolic BP of 90 mmHg or higher). First-line antihypertensive medications include ACE inhibitors, amlodipine, or thiazide-like diuretics based on individual circumstances. Regular monitoring and reassessment to adjust treatment according to patient response are also essential. | [
{
"from": "human",
"value": "Provide a concise summary of the NICE guidelines for hypertension management."
},
{
"from": "gpt",
"value": "The NICE guidelines for hypertension management recommend that adults aged 40 to 74 should undergo regular blood pressure checks. For those with stage 1 hypertension (systolic BP between 130-139 mmHg or diastolic BP between 80-89 mmHg), lifestyle changes such as diet modifications, increased physical activity, and weight loss should be advised. Drug treatment is recommended for stage 2 hypertension (systolic BP of 140 mmHg or higher or diastolic BP of 90 mmHg or higher). First-line antihypertensive medications include ACE inhibitors, amlodipine, or thiazide-like diuretics based on individual circumstances. Regular monitoring and reassessment to adjust treatment according to patient response are also essential."
}
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English | 10 | Provide information about a medical condition. | What are the common symptoms of anxiety disorders? | <noinput> | Common symptoms of anxiety disorders include persistent worry or fear, restlessness, difficulty concentrating, irritability, muscle tension, and sleep disturbances. Physical symptoms may also manifest, such as increased heart rate, sweating, trembling, or gastrointestinal issues. In some cases, individuals may experience panic attacks, characterized by sudden episodes of intense fear and physical symptoms such as chest pain and shortness of breath. | [
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"value": "Common symptoms of anxiety disorders include persistent worry or fear, restlessness, difficulty concentrating, irritability, muscle tension, and sleep disturbances. Physical symptoms may also manifest, such as increased heart rate, sweating, trembling, or gastrointestinal issues. In some cases, individuals may experience panic attacks, characterized by sudden episodes of intense fear and physical symptoms such as chest pain and shortness of breath."
}
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] | 754.150942 |
English | 10 | Create a differential diagnosis list. | List possible conditions that could cause these symptoms: fatigue, weight loss, and night sweats. | Patient is a 55-year-old male presenting with persistent fatigue, unexplained weight loss of 5 kg over the last month, and night sweats. He has a history of smoking and mild COPD. | 1. Malignancy (e.g., lung cancer or lymphoma)
2. Tuberculosis
3. Hyperthyroidism
4. Chronic infection (e.g., HIV or endocarditis)
5. Chronic obstructive pulmonary disease exacerbation
6. Depression/anxiety
7. Diabetes mellitus | [
{
"from": "human",
"value": "List possible conditions that could cause these symptoms: fatigue, weight loss, and night sweats.\nPatient is a 55-year-old male presenting with persistent fatigue, unexplained weight loss of 5 kg over the last month, and night sweats. He has a history of smoking and mild COPD."
},
{
"from": "gpt",
"value": "1. Malignancy (e.g., lung cancer or lymphoma) \n2. Tuberculosis \n3. Hyperthyroidism \n4. Chronic infection (e.g., HIV or endocarditis) \n5. Chronic obstructive pulmonary disease exacerbation\n6. Depression/anxiety\n7. Diabetes mellitus"
}
] | [
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] | 754.150942 |
English | 10 | Classify medication types. | Categorize the following medications into their respective classes: Amoxicillin, Metformin, Simvastatin, and Omeprazole. | Amoxicillin, Metformin, Simvastatin, Omeprazole. | 1. **Amoxicillin** - Antibiotic (Penicillin class)
2. **Metformin** - Antidiabetic (Biguanide class)
3. **Simvastatin** - Antihyperlipidemic (Statin class)
4. **Omeprazole** - Proton Pump Inhibitor (PPI) | [
{
"from": "human",
"value": "Categorize the following medications into their respective classes: Amoxicillin, Metformin, Simvastatin, and Omeprazole.\nAmoxicillin, Metformin, Simvastatin, Omeprazole."
},
{
"from": "gpt",
"value": "1. **Amoxicillin** - Antibiotic (Penicillin class)\n2. **Metformin** - Antidiabetic (Biguanide class)\n3. **Simvastatin** - Antihyperlipidemic (Statin class)\n4. **Omeprazole** - Proton Pump Inhibitor (PPI)"
}
] | [
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] | 754.150942 |
English | 10 | Step-by-step reasoning in the diagnosis of hypertension. | Outline the step-by-step approach for diagnosing a 52-year-old male presented with consistently elevated blood pressure readings. | A 52-year-old male presents to his GP with blood pressure readings averaging 150/95 mmHg taken over several visits. He reports a family history of hypertension and has no significant prior medical history. He is a non-smoker, moderately active, and has a BMI of 32 kg/m². | 1. Review the patient's medical history for past hypertension or cardiovascular issues.
2. Assess the patient's family history for cardiovascular diseases, especially hypertension.
3. Confirm the diagnosis by taking several blood pressure measurements across different visits (at least 3 over a month).
4. Rule out secondary causes of hypertension by conducting laboratory tests (kidney function tests, electrolytes, etc.).
5. Evaluate lifestyle factors, including diet, exercise, alcohol consumption, and stress levels.
6. If secondary causes are excluded, classify the hypertension as primary.
7. Discuss potential treatment options with the patient, including lifestyle modifications and pharmacotherapy. | [
{
"from": "human",
"value": "Outline the step-by-step approach for diagnosing a 52-year-old male presented with consistently elevated blood pressure readings.\nA 52-year-old male presents to his GP with blood pressure readings averaging 150/95 mmHg taken over several visits. He reports a family history of hypertension and has no significant prior medical history. He is a non-smoker, moderately active, and has a BMI of 32 kg/m²."
},
{
"from": "gpt",
"value": "1. Review the patient's medical history for past hypertension or cardiovascular issues.\n2. Assess the patient's family history for cardiovascular diseases, especially hypertension.\n3. Confirm the diagnosis by taking several blood pressure measurements across different visits (at least 3 over a month).\n4. Rule out secondary causes of hypertension by conducting laboratory tests (kidney function tests, electrolytes, etc.).\n5. Evaluate lifestyle factors, including diet, exercise, alcohol consumption, and stress levels.\n6. If secondary causes are excluded, classify the hypertension as primary.\n7. Discuss potential treatment options with the patient, including lifestyle modifications and pharmacotherapy."
}
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English | 10 | Open-ended generation on diabetes management. | Discuss effective strategies for managing type 2 diabetes in adults. | <noinput> | Effective management strategies for type 2 diabetes in adults include: 1. Regular monitoring of blood glucose levels to maintain control within target ranges. 2. Implementing a balanced diet rich in whole grains, vegetables, lean proteins, and healthy fats while minimizing refined sugars and carbohydrates. 3. Engaging in regular physical activity; at least 150 minutes of moderate exercise per week is recommended. 4. Weight management to reduce insulin resistance and improve overall metabolic health. 5. Medication adherence, which may include oral hypoglycaemics or insulin therapy as prescribed. 6. Regular follow-ups with healthcare professionals to adjust treatment plans based on progress and any emerging complications. 7. Education on recognizing and managing potential complications, such as neuropathy or retinopathy. | [
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"value": "Discuss effective strategies for managing type 2 diabetes in adults."
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{
"from": "gpt",
"value": "Effective management strategies for type 2 diabetes in adults include: 1. Regular monitoring of blood glucose levels to maintain control within target ranges. 2. Implementing a balanced diet rich in whole grains, vegetables, lean proteins, and healthy fats while minimizing refined sugars and carbohydrates. 3. Engaging in regular physical activity; at least 150 minutes of moderate exercise per week is recommended. 4. Weight management to reduce insulin resistance and improve overall metabolic health. 5. Medication adherence, which may include oral hypoglycaemics or insulin therapy as prescribed. 6. Regular follow-ups with healthcare professionals to adjust treatment plans based on progress and any emerging complications. 7. Education on recognizing and managing potential complications, such as neuropathy or retinopathy."
}
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] | 754.150942 |
English | 10 | Classification of medication. | Classify the following medications into appropriate categories: Metformin, Insulin, Acarbose, and Gliptins. | <noinput> | 1. Metformin - Biguanides (oral hypoglycaemics)
2. Insulin - Insulin replacement therapy (hormonal)
3. Acarbose - Alpha-glucosidase inhibitors (oral hypoglycaemics)
4. Gliptins - Dipeptidyl peptidase-4 (DPP-4) inhibitors (oral hypoglycaemics) | [
{
"from": "human",
"value": "Classify the following medications into appropriate categories: Metformin, Insulin, Acarbose, and Gliptins."
},
{
"from": "gpt",
"value": "1. Metformin - Biguanides (oral hypoglycaemics)\n2. Insulin - Insulin replacement therapy (hormonal)\n3. Acarbose - Alpha-glucosidase inhibitors (oral hypoglycaemics)\n4. Gliptins - Dipeptidyl peptidase-4 (DPP-4) inhibitors (oral hypoglycaemics)"
}
] | [
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] | 754.150942 |
English | 10 | Diagnostic Question | What are the common symptoms associated with hyperthyroidism? | <noinput> | Common symptoms of hyperthyroidism include:
1. Increased heart rate (tachycardia)
2. Unexplained weight loss despite normal or increased appetite
3. Increased sensitivity to heat
4. Nervousness, anxiety, or irritability
5. Tremors (shaking hands or fingers)
6. Sweating
7. Menstrual changes in women, such as lighter or less frequent periods
8. Sleep disturbances, including insomnia
9. Fatigue or muscle weakness, especially in the upper arms and thighs
10. Goitre (enlargement of the thyroid gland) that may cause swelling at the base of the neck. | [
{
"from": "human",
"value": "What are the common symptoms associated with hyperthyroidism?"
},
{
"from": "gpt",
"value": "Common symptoms of hyperthyroidism include:\n1. Increased heart rate (tachycardia)\n2. Unexplained weight loss despite normal or increased appetite\n3. Increased sensitivity to heat\n4. Nervousness, anxiety, or irritability\n5. Tremors (shaking hands or fingers)\n6. Sweating\n7. Menstrual changes in women, such as lighter or less frequent periods\n8. Sleep disturbances, including insomnia\n9. Fatigue or muscle weakness, especially in the upper arms and thighs\n10. Goitre (enlargement of the thyroid gland) that may cause swelling at the base of the neck."
}
] | [
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