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f58d76481b462c18a2a23667e0a4236807da65c20558ad73a23f4051021d4c87 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Although adverse effects are usually mild , the author reports here a case of leucocytopenia and thrombocytopenia with quetiapine treatment that required its discontinuation ."} | [{"head": "leucocytopenia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "quetiapine", "tail_type": "", "tail_pos": []}, {"head": "thrombocytopenia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "quetiapine", "tail_type": "", "tail_pos": []}] |
ffc45ab20bdb5561d0bcc33c4fa61f1b1af94be0fb4faa2f6b3a59b62d8bb603 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Methanol toxicity can cause severe central nervous system insult in which a characteristic pattern of bilateral putaminal injury is noted on brain imaging studies ."} | [{"head": "bilateral putaminal injury", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Methanol", "tail_type": "", "tail_pos": []}, {"head": "Methanol toxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Methanol", "tail_type": "", "tail_pos": []}, {"head": "severe central nervous system insult", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Methanol", "tail_type": "", "tail_pos": []}] |
167f38987c5acf8abbc2b29a286fa82bec12c6ca23bbaf39fe06fcd7c8b42800 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The authors caution that treatment with alprazolam may be complicated by the induction of mania ."} | [{"head": "mania", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "alprazolam", "tail_type": "", "tail_pos": []}] |
fd83a866465cb2f4ec20327c2d734f828ad35ce0e8adef47a68d0eafdf61d6f5 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "CASE PRESENTATION : Three cases of Leishmania infantum leishmaniasis in corticosteroid ( CS ) - treated patients are reported : an isolated lingual leishmaniasis in a farmer treated with CS for asthma , a severe visceral leishmaniasis associated with cutaneous lesions in a woman with myasthenia gravis , and a visceral involvement after cutaneous leishmaniasis in a man receiving CS ."} | [{"head": "cutaneous leishmaniasis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "CS", "tail_type": "", "tail_pos": []}, {"head": "Leishmania infantum leishmaniasis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "corticosteroid", "tail_type": "", "tail_pos": []}, {"head": "Leishmania infantum leishmaniasis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "CS", "tail_type": "", "tail_pos": []}, {"head": "lingual leishmaniasis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "corticosteroid", "tail_type": "", "tail_pos": []}, {"head": "lingual leishmaniasis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "CS", "tail_type": "", "tail_pos": []}] |
a2a68e671a6856d47802bace6c5ed9433ba3ceaee0f4f1191b8050e286cc1bde | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "No other endogenous or exogenous cause for the gynecomastia could be found except for the theophylline ."} | [{"head": "gynecomastia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "theophylline", "tail_type": "", "tail_pos": []}] |
c0fc9f28cbdfe30fe478ea4933a3ece95c6b3f8e18c253869707d49b78f28c6d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "SLE receded after withdrawal of carbamazepine and treatment with anti - inflammatory drugs ."} | [{"head": "SLE", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "carbamazepine", "tail_type": "", "tail_pos": []}] |
0e95aa7a0e9294fa4eb23d913ca65db8400fa41751f4669c2ca9e5951f4429ae | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Decreased plasma cortisol level during alprazolam treatment of panic disorder : a case report ."} | [{"head": "Decreased plasma cortisol level", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "alprazolam", "tail_type": "", "tail_pos": []}] |
1e40ae1f6671ad78f487fe7c5036079f8923a378ce1703b0a3a50e2789a0cc0e | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Adverse effects of amiodarone including pulmonary toxicity , hepatotoxicity , aggravation of arrhythmia , and thyroid diseases are well understood ."} | [{"head": "aggravation of arrhythmia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amiodarone", "tail_type": "", "tail_pos": []}, {"head": "hepatotoxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amiodarone", "tail_type": "", "tail_pos": []}, {"head": "pulmonary toxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amiodarone", "tail_type": "", "tail_pos": []}, {"head": "thyroid diseases", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amiodarone", "tail_type": "", "tail_pos": []}] |
21c4f69d5e5ac8741fdb6e6e57a326b1d4f4510a591b51a6ba5e09bd1b36f56d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We describe a patient who experienced chronic nausea and an episode of confusion while treated with a small , stable dose of oral morphine in the setting of mild renal insufficiency ."} | [{"head": "chronic nausea", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "morphine", "tail_type": "", "tail_pos": []}, {"head": "confusion", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "morphine", "tail_type": "", "tail_pos": []}] |
3560c0e6e7ab70b14dbf198fde893102b4b0f843cf1c87402803891e02b7c050 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "This is the first report of a disulfiram - like reaction with cefmenoxime ."} | [{"head": "disulfiram - like reaction", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "cefmenoxime", "tail_type": "", "tail_pos": []}] |
19b19a0c09ec90fe2ff291749f212ffda76ea902ea824ac8d9a3844f6ad7ded6 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Although neurotoxicity is a frequent complication of methotrexate therapy , fatal acute neurotoxicity is extremely uncommon , especially in adults ."} | [{"head": "fatal acute neurotoxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "methotrexate", "tail_type": "", "tail_pos": []}, {"head": "neurotoxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "methotrexate", "tail_type": "", "tail_pos": []}] |
6c416622add26ea8abdd6676f12b54340316801cca8979cdca4ace663c4f0f4d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The objective of this report is to describe a case of fixed drug eruption that occurred during omeprazole treatment ."} | [{"head": "eruption", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "omeprazole", "tail_type": "", "tail_pos": []}] |
b0e51161f791726be4c35da6b1bd2d1f6929ccaad88f61d183aea2795ec45bd7 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Possible mechanisms for damage to the urothelium by ketamine are suggested ."} | [{"head": "damage to the urothelium", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ketamine", "tail_type": "", "tail_pos": []}] |
ae8ba6c444cda38fe1d0a2f921a763331b6177005559d238cac93cd47ae5e0ff | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The abnormal rhythm disappeared with the withdrawal of propranolol and when the drug was restarted a 2/1 S - A block was seen ."} | [{"head": "abnormal rhythm", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "propranolol", "tail_type": "", "tail_pos": []}] |
4fb0e4b0525ef8c6f041c0962eb8712cedaf5524dd1cbfd34f43deb0d213fd5e | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "In addition to the recognized arrhythmic complications , the authors emphasize myocardial necrosis as a possible further manifestation of amsacrine - related cardiotoxicity ."} | [{"head": "cardiotoxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amsacrine", "tail_type": "", "tail_pos": []}, {"head": "myocardial necrosis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amsacrine", "tail_type": "", "tail_pos": []}] |
bf5c06dfddea89705c53b5b62fb936f013e8bb32025bc29832b1160f06d6be0f | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Despite a hematologic response in all 3 patients , none of them achieved cytogenetic remission , and all progressed to blast crisis at 7 to 10 months of imatinib therapy ."} | [{"head": "blast crisis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "imatinib", "tail_type": "", "tail_pos": []}] |
8bda1d8c107fd480d1be9b6ad3e350b8cecca338d7b1162f879a185f5acbd0c8 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Since early symptoms of the toxic effects of theophylline can mimic peptic ulcer disease , cimetidine might be prescribed for the gastrointestinal symptoms with subsequent worsening of theophylline poisoning ."} | [{"head": "peptic ulcer disease", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "theophylline", "tail_type": "", "tail_pos": []}] |
2bf6068895c4fd20a5b5209c651ec06e8214755034ea1d1ec74a859dc4a7e34d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Occult quinine - induced thrombocytopenia ."} | [{"head": "thrombocytopenia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "quinine", "tail_type": "", "tail_pos": []}] |
3906694454e23fd202c40edbbdbda9dad9594ed883989b0b83f126537ddbe4c0 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We report four cases of severe corneal ulceration in methamphetamine abusers ."} | [{"head": "severe corneal ulceration", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "methamphetamine", "tail_type": "", "tail_pos": []}] |
be624bac72b03ad475b6e027722872f245452589ecab26b09342ab46110d64f8 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Despite the known pulmonary side effects of nitrofurantoin , there is no report of this toxicity occurring in pregnant patients ."} | [{"head": "pulmonary side effects", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "nitrofurantoin", "tail_type": "", "tail_pos": []}] |
a6529354bb8c9b60f0c85ffdf70a5e68a5dd1b5b4117bbf1dc263d6dfea274be | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "These skin lesions may be induced or worsened during antiviral therapy with interferon - alpha ( IFN ) ."} | [{"head": "skin lesions", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "IFN", "tail_type": "", "tail_pos": []}, {"head": "skin lesions", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "interferon - alpha", "tail_type": "", "tail_pos": []}] |
b57b84ee573ba36a0de78ce2d775f167947707001216f4ff9309605baca03e54 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A patient with seropositive rheumatoid arthritis developed ascites while taking weekly doses of methotrexate ( MTX ) ."} | [{"head": "ascites", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "methotrexate", "tail_type": "", "tail_pos": []}, {"head": "ascites", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "MTX", "tail_type": "", "tail_pos": []}] |
78919efdcc91ff82c91d1c1c7c4c813a1a1c8ea555dae3bc4f373b9355cfc158 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Cicatricial entropion associated with chronic dipivefrin application ."} | [{"head": "Cicatricial entropion", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "dipivefrin", "tail_type": "", "tail_pos": []}] |
3ed7795b2d6c5511b7b196b0adaeff187eac1705f039782aaa6393bf9d4c9c4c | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Severe symptomatic hyponatremia during sibutramine therapy : a case report ."} | [{"head": "Severe symptomatic hyponatremia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "sibutramine", "tail_type": "", "tail_pos": []}] |
d2591a2ae1a422d0f869bef15d7080d4b750e132dfc220913675da6bd9d1898a | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Gemcitabine - related radiation recall preferentially involves internal tissue and organs ."} | [{"head": "radiation recall", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Gemcitabine", "tail_type": "", "tail_pos": []}] |
4ab068a2178c8dd0ade9ee2825419773958e6f05d4a8699cb851746f2b824106 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A 54-year - old man developed TEN 4 weeks after beginning lamotrigine for complex partial seizures related to a glioblastoma multiforme brain tumor ."} | [{"head": "TEN", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "lamotrigine", "tail_type": "", "tail_pos": []}] |
6eea491d91238132c0ce61d4562f7a7533ed65ec41f16c75a256821f1387f214 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A second episode of jaundice followed the intravaginal administration of a mixture of furazolidone and nifuroxime ."} | [{"head": "jaundice", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "furazolidone", "tail_type": "", "tail_pos": []}, {"head": "jaundice", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "nifuroxime", "tail_type": "", "tail_pos": []}] |
f28b7c97bffc7a66ff1ed1cb1fc46635a9d9748f5cdda64a35510db0fac6d14b | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Intracranial haemorrhage from a meningioma in a patient receiving aspirin prophylaxis : a case report ."} | [{"head": "Intracranial haemorrhage", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "aspirin", "tail_type": "", "tail_pos": []}] |
7f3020bbfcb119bea0e879cd14530afd22ecff4ed8dbe43d0519482cddbe8a7d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "This case illustrates the potential decoupling of PSA response from disease status in flutamide withdrawal ."} | [{"head": "decoupling of PSA response", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "flutamide", "tail_type": "", "tail_pos": []}] |
f2c19d808efab2e02033a4b4d189809d1bd348ba5d071269c8a36194937fdb13 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A 9-year - old boy developed acute renal failure following intravenous acyclovir ( 30 mg / kg per day ) administered for 6 days to treat herpetic encephalitis ."} | [{"head": "acute renal failure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "acyclovir", "tail_type": "", "tail_pos": []}] |
01c5fd7547dd39753009b553eca237e32e75731881027343b03f9e2503bd12e8 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Methotrexate - induced papular eruption following treatment of psoriasis has not been previously reported ."} | [{"head": "papular eruption", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Methotrexate", "tail_type": "", "tail_pos": []}] |
135dd93b430b9fea836ae0f5195e9bd8329a80c3d17d35ca34fbc2bd0be7ee5c | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "CONCLUSIONS : There is very little published information regarding ofloxacin - induced toxic epidermal necrolysis ."} | [{"head": "toxic epidermal necrolysis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ofloxacin", "tail_type": "", "tail_pos": []}] |
765ea2c782fe6311f7853b1c54da69b8c94edebae6b7b50e789cac1bf0164351 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Secondary hyperparathyroidism in certain patients with lithium nephrotoxicity is also possible ."} | [{"head": "nephrotoxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "lithium", "tail_type": "", "tail_pos": []}, {"head": "Secondary hyperparathyroidism", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "lithium", "tail_type": "", "tail_pos": []}] |
1763ac54b3bc09f3b8eea0dc3e9926ce78e84f97c3d7437ded7f370bb460e6ad | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We describe the development of ischemic colitis in a woman who was treated with tegaserod and review the relationship among ischemic colitis , tegaserod use , and irritable bowel syndrome ."} | [{"head": "irritable bowel syndrome", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "tegaserod", "tail_type": "", "tail_pos": []}, {"head": "ischemic colitis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "tegaserod", "tail_type": "", "tail_pos": []}] |
f874e8e65b9bba42688a9079dc79a868331479579782896b81e96d1ce4f1b25d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "In view of our experience in the present case , it should be stressed that close monitoring of coagulation capacity is necessary in critically ill patients in order to avoid fatal haemorrhage after initiating warfarin therapy regardless of the dosage ."} | [{"head": "fatal haemorrhage", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "warfarin", "tail_type": "", "tail_pos": []}] |
23be4f3a7dc8242edfe0b3fffa5e8e6f10b7b7262bbfdb5fed2266d6ac98353f | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "For patients who suffer from osteogenic sarcoma and have anaphylactic reactions to MTX , this desensitization protocol will allow these patients to continue with needed therapeutic or palliative chemotherapy ."} | [{"head": "anaphylactic reactions", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "MTX", "tail_type": "", "tail_pos": []}] |
803cb69bd4df0478924ede0595d131fa17e705c7b5d8c8b80491ccf5d6b47afd | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Three of these patients had convulsions attributed to imipenem / cilastatin ; 3.6 % of the patients had seizure , or 2 % of imipenem / cilastatin administrations was followed by a seizure attack ."} | [{"head": "convulsions", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "cilastatin", "tail_type": "", "tail_pos": []}, {"head": "convulsions", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "imipenem", "tail_type": "", "tail_pos": []}, {"head": "seizure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "cilastatin", "tail_type": "", "tail_pos": []}, {"head": "seizure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "imipenem", "tail_type": "", "tail_pos": []}] |
c82807ff2c9137c09f47249fd74405d63254bcb584bf1b3e067ced095a0a9a73 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "DISCUSSION : Electrolyte disorders associated with foscarnet are reviewed ."} | [{"head": "Electrolyte disorders", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "foscarnet", "tail_type": "", "tail_pos": []}] |
2f9c841bbbfa9bf6da6993e2401ae1ebbfe354974e94a32288f50a5fa79d7d11 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "When DSCG was withdrawn , urticaria vanished and the child remained symptom - free ."} | [{"head": "urticaria", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "DSCG", "tail_type": "", "tail_pos": []}] |
cf883be0b40f6a33d0a2c120d958abb013d159792168396320f4cd31b2c10037 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A case is presented in which a 68-year - old man became delirious after being withdrawn from a low dosage of alprazolam ."} | [{"head": "delirious", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "alprazolam", "tail_type": "", "tail_pos": []}] |
92306abbfe06510d22122d897e320c9637555c35f4a5f466567076f78688af4f | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Capecitabine was discontinued and the allergic reactions resolved after the woman took diphenhydramine for 1 week ."} | [{"head": "allergic reactions", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Capecitabine", "tail_type": "", "tail_pos": []}] |
b29c12bc8303252a969ceccb020ed503ec48cb26b14c3958871e0de217474e25 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A patient with alcoholic cerebellar degeneration had periodic alternating nystagmus during a period of phenytoin intoxication ."} | [{"head": "periodic alternating nystagmus", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "phenytoin", "tail_type": "", "tail_pos": []}] |
0c9c45a926240aa891150527d8d63b00fcb7c349f4579f75add0f24d358bc4d9 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "When cyanamide - treated alcoholics relapse into drinking , more severe inflammation develops in the liver ."} | [{"head": "inflammation", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "cyanamide", "tail_type": "", "tail_pos": []}] |
1a136c3b064411103c31dd7daa42accd43fc0341dca368f66816de585080080d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "This article describes a patient with suspected ciprofloxacin - induced interstitial nephritis ."} | [{"head": "interstitial nephritis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ciprofloxacin", "tail_type": "", "tail_pos": []}] |
075bda4533c612dd92390e3e9c5e36b3aff7515dbaec699c92656f70da9d6091 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "RESULTS : A patient developed a bilaterally symmetric bull's - eye maculopathy 45 years after taking quinacrine for 18 months as prophylaxis against malaria ."} | [{"head": "bilaterally symmetric bull's - eye maculopathy", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "quinacrine", "tail_type": "", "tail_pos": []}] |
fd4a3f780bbb189812154a7e41b4f71149b8366868612482195f73b427de0d5e | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Hepatocellular damage following therapeutic intravenous iron sucrose infusion in a child ."} | [{"head": "Hepatocellular damage", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "iron sucrose", "tail_type": "", "tail_pos": []}] |
bd5a769a1d6bd8ff61d0d65a476879be37173ae1543254d4ebebe488446a1dfd | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Magnesium toxicosis in two horses ."} | [{"head": "Magnesium toxicosis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Magnesium", "tail_type": "", "tail_pos": []}] |
737ef3ab8b0c8cd4153ffba5629bee09e39e4d1fd4493718aa7513d9cd4fab0d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Anaphylaxis to intrathecal diamorphine ."} | [{"head": "Anaphylaxis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "diamorphine", "tail_type": "", "tail_pos": []}] |
15e0a22845f2a7b8cbfda5c20418b6ac66560ec39f93849d2b5ae66b59bb0e7d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "This report describes a case of flucytosine - associated ulcerating enteritis in which the small bowel x - ray demonstrated severe luminal narrowing , ulceration , and marked separation of loops of bowel ."} | [{"head": "marked separation of loops of bowel", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "flucytosine", "tail_type": "", "tail_pos": []}, {"head": "severe luminal narrowing", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "flucytosine", "tail_type": "", "tail_pos": []}, {"head": "ulcerating enteritis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "flucytosine", "tail_type": "", "tail_pos": []}, {"head": "ulceration", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "flucytosine", "tail_type": "", "tail_pos": []}] |
6b1fea6c762f72662011edf71de7821ed4f1901d9fe8ce2abccb3be1ccc53e94 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "He developed recurrent skin rash , fever , hypereosinophilia , and acute renal failure after rechallenge with chlorambucil ."} | [{"head": "acute renal failure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "chlorambucil", "tail_type": "", "tail_pos": []}, {"head": "fever", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "chlorambucil", "tail_type": "", "tail_pos": []}, {"head": "hypereosinophilia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "chlorambucil", "tail_type": "", "tail_pos": []}, {"head": "skin rash", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "chlorambucil", "tail_type": "", "tail_pos": []}] |
72eaab90e6e5472145f687cbbca95135ec9911cb4a2b8dff9524f4dbe1466e05 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A typical case of dextran-40 associated acute renal failure is presented ."} | [{"head": "acute renal failure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "dextran-40", "tail_type": "", "tail_pos": []}] |
4cdfd9197ccf91a03adc4ce885fa5b885fba46afb77c15cfd12e0950cdcb22ac | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Amphotericin B ( AmB ) is effective , but its use is limited by toxicity : renal impairment , anaemia , fever , malaise , and hypokalaemia are common ."} | [{"head": "anaemia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AmB", "tail_type": "", "tail_pos": []}, {"head": "anaemia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Amphotericin B", "tail_type": "", "tail_pos": []}, {"head": "fever", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AmB", "tail_type": "", "tail_pos": []}, {"head": "fever", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Amphotericin B", "tail_type": "", "tail_pos": []}, {"head": "hypokalaemia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AmB", "tail_type": "", "tail_pos": []}, {"head": "hypokalaemia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Amphotericin B", "tail_type": "", "tail_pos": []}, {"head": "malaise", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AmB", "tail_type": "", "tail_pos": []}, {"head": "malaise", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Amphotericin B", "tail_type": "", "tail_pos": []}, {"head": "renal impairment", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AmB", "tail_type": "", "tail_pos": []}, {"head": "renal impairment", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Amphotericin B", "tail_type": "", "tail_pos": []}] |
4a6d55794dd23e284cfbe9d196240f3cd994a55b4ff272fb7ff514ca34664fb8 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "OBJECTIVE : To report a case of possible foscarnet - induced severe hypomagnesemia and other electrolyte disorders ."} | [{"head": "electrolyte disorders", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "foscarnet", "tail_type": "", "tail_pos": []}, {"head": "severe hypomagnesemia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "foscarnet", "tail_type": "", "tail_pos": []}] |
73cd71c63bd4efe72f60733cd7b0213cd660c48638f0259d50145a10044bc65d | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Ziprasidone is an atypical antipsychotic drug that is believed to have a low propensity for inducing extrapyramidal symptoms , including tardive dyskinesia ( TD ) ."} | [{"head": "extrapyramidal symptoms", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Ziprasidone", "tail_type": "", "tail_pos": []}, {"head": "tardive dyskinesia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Ziprasidone", "tail_type": "", "tail_pos": []}, {"head": "TD", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Ziprasidone", "tail_type": "", "tail_pos": []}] |
e8b9a88b1a1e069533c6dc169570d71e927e2ee150590dcb0e08291a01bf46d1 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Reported are three children who developed progressive paraparesis after intrathecal methotrexate administration followed by complete or partial recovery ."} | [{"head": "progressive paraparesis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "methotrexate", "tail_type": "", "tail_pos": []}] |
6822faf11438c649ec34021f3490bfb3f9ad5715db4528e6e313c3bdae7829e3 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "As far as we know , this is the first case report of acute hemorrhagic gastritis associated with AZ intoxication ."} | [{"head": "acute hemorrhagic gastritis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AZ", "tail_type": "", "tail_pos": []}, {"head": "AZ intoxication", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "AZ", "tail_type": "", "tail_pos": []}] |
da02ae904c08b9e11db06ab9580a61b8a5997dc7d271a5468916ff8d1795987c | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Since recent studies have reported no negative interactions with concurrent use , we here report three cases ( one case of a prolonged seizure , a serotonin syndrome and a focal seizure ) of severe lithium - induced side effects while patients underwent ECT without complications and lithium serum levels were still subtherapeutic ."} | [{"head": "focal seizure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "lithium", "tail_type": "", "tail_pos": []}, {"head": "prolonged seizure", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "lithium", "tail_type": "", "tail_pos": []}, {"head": "serotonin syndrome", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "lithium", "tail_type": "", "tail_pos": []}] |
75c231e990f9573eb2013e47b7dec4b4b137667638165603231837c10002a728 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Sensorimotor polyneuropathy with 5-aminosalicylic acid : a case report ."} | [{"head": "Sensorimotor polyneuropathy", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "5-aminosalicylic acid", "tail_type": "", "tail_pos": []}] |
97323043453c890d9f834bd5446753e689c03d6441887fcdddbb1f317dad3d3a | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Two of the five patients who worsened motorically also developed encephalopathy during risperidone treatment ; the encephalopathy resolved when the patients were switched to clozapine treatment ."} | [{"head": "encephalopathy", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "risperidone", "tail_type": "", "tail_pos": []}, {"head": "worsened motorically", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "risperidone", "tail_type": "", "tail_pos": []}] |
4bd37104c4407ab53b0a53f52186f49289189ebb774ddd9a31e70e0c9652ed1f | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We strongly suspect that this lethal anuria was mainly due to ifosfamide , occurring in a patient having received previous cisplatin chemotherapy and with poor kidney perfusion due to transient hypotension ."} | [{"head": "lethal anuria", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ifosfamide", "tail_type": "", "tail_pos": []}] |
146a0ca51447c4237935ad874b5a1761d89c63db7add80fae402b2f96b44dd2b | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "An intertrigo - like eruption from pegylated liposomal doxorubicin ."} | [{"head": "intertrigo - like eruption", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "doxorubicin", "tail_type": "", "tail_pos": []}] |
a969214c6b820754acf865bc5982891e2178d6f570d72a37ec05e58084ea079b | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "CONCLUSIONS : We present a case of a patient with CML who developed KS 12 months after starting treatment with imatinib 400 mg / d ."} | [{"head": "KS", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "imatinib", "tail_type": "", "tail_pos": []}] |
fb5c11d828314fa76387d533e5714f30ae9af33ab496bb648e8370d7e3672aac | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Interstitial lung disease ( ILD ) related to therapy with the drug gefitinib has been well reported ."} | [{"head": "ILD", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "gefitinib", "tail_type": "", "tail_pos": []}, {"head": "Interstitial lung disease", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "gefitinib", "tail_type": "", "tail_pos": []}] |
451bdc917192a089c6b26b5afbdabc1ba956f5cf9a970835e4912af578c84619 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A case of acute subdural haematoma originating spontaneously from an angiomatous meningioma in a patient receiving prophylactic aspirin therapy is presented ."} | [{"head": "acute subdural haematoma", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "aspirin", "tail_type": "", "tail_pos": []}] |
cebf845a96cee26284cb5d2e8dbbb57f25d674b9372ce92bae2373910544e7c0 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Flucytosine - associated diarrhea has been previously described in 6%-10 % of patients receiving the drug ."} | [{"head": "diarrhea", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Flucytosine", "tail_type": "", "tail_pos": []}] |
fc3455fd2316e0bc000687582ecbf68fd06b8f7bb8463beaee811f6b537f4b51 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Comparable adverse effects , such as disorientation and temporary amnesia , have been reported in patients in the analogous agent , propranolol ."} | [{"head": "disorientation", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "propranolol", "tail_type": "", "tail_pos": []}, {"head": "temporary amnesia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "propranolol", "tail_type": "", "tail_pos": []}] |
6037361dc195cb1d4d502030a6f99e03327cc7e9f4c1c92c9cd218ac560fa227 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Neurophysiological mechanisms which aid in elucidating the role of disulfiram in the etiology of catatonia are discussed ."} | [{"head": "catatonia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "disulfiram", "tail_type": "", "tail_pos": []}] |
c33d6be781d44b8f00d2c25b992deada6912a7008b70140f5b104ba5daf106ce | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "According to the Naranjo adverse drug reaction probability scale , the likelihood that temozolomide was responsible for the adverse drug reaction of fever was probable ( score of 6 ) ."} | [{"head": "fever", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "temozolomide", "tail_type": "", "tail_pos": []}] |
3feeffe83f80b621e060ba4f95aa76987d3ba6ad4581176d747883a2998d78c2 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Hemodynamic collapse following labetalol administration in preeclampsia ."} | [{"head": "Hemodynamic collapse", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "labetalol", "tail_type": "", "tail_pos": []}] |
86bb68faa14dd1f32d12cda36a8697755ee411832816e413d733b93b9970e253 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The cause is presumed to be secondary to hypercoagulability due to asparaginase - induced antithrombin III deficiency ."} | [{"head": "antithrombin III deficiency", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "asparaginase", "tail_type": "", "tail_pos": []}] |
84781d8f00806eec6796f80bd8c0c793a846280b17c92e5c8fb58f812de93257 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Bisphosphonate induced osteochemonecrosis of the jaw mimicking a tumour ."} | [{"head": "osteochemonecrosis of the jaw", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Bisphosphonate", "tail_type": "", "tail_pos": []}] |
5637c99e434d74ae73e8d0e99e4ae745b8f4b9d8e44396351229eda20c86bdea | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Patients receiving amifostine who develop only fever should be evaluated for an adverse drug reaction , as well as for sepsis and fevers of neutropenia , and it may be necessary to discontinue the drug ."} | [{"head": "fever", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amifostine", "tail_type": "", "tail_pos": []}, {"head": "fevers of neutropenia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amifostine", "tail_type": "", "tail_pos": []}, {"head": "sepsis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amifostine", "tail_type": "", "tail_pos": []}] |
469646f4870a60111d3cf42643c4676f69af25434554a924d5a3d68592022495 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Pemphigus foliaceus induced by rifampicin ."} | [{"head": "Pemphigus foliaceus", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "rifampicin", "tail_type": "", "tail_pos": []}] |
d2456eec8e428506a020a58a24d200e3bfc7725f16b5358112097d8483f6c939 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Heparin - dependent antibodies and thrombosis without heparin - induced thrombocytopenia ."} | [{"head": "thrombocytopenia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "heparin", "tail_type": "", "tail_pos": []}] |
ae5e4b3cd658389ff86b1a0b6a6f8d190468f430a1e5a4d6be2d2ec63573372b | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Experience with five patients in whom impaired renal function developed early during amphotericin B therapy is reported ."} | [{"head": "impaired renal function", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "amphotericin B", "tail_type": "", "tail_pos": []}] |
772549bc913aa9db3cb614537fa30f0c29496594a714dcb34eb9bd484545c7a7 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Ampicillin - induced interstitial nephritis with generalised exfoliative dermatitis ."} | [{"head": "generalised exfoliative dermatitis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Ampicillin", "tail_type": "", "tail_pos": []}, {"head": "interstitial nephritis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Ampicillin", "tail_type": "", "tail_pos": []}] |
bf6f96e29b9f9c305103363c9a6ff193205d5cc1088961eaa11e2b2b692dfa51 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "OBJECTIVE : To report a case of reversible nonthrombocytopenic palpable purpura associated with metoclopramide ."} | [{"head": "nonthrombocytopenic palpable purpura", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "metoclopramide", "tail_type": "", "tail_pos": []}] |
56717159a828ab20a93bd5d4b82c3ef4ad58c62ce50ebf34adff4e02d66ec7c0 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Vancomycin - induced vasculitis ."} | [{"head": "vasculitis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Vancomycin", "tail_type": "", "tail_pos": []}] |
79ca7f727be54a51cc22346bb84036cec9925ac694219d677f1037dc5739ca4a | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A new case of Creutzfeldt - Jakob disease associated with human growth hormone therapy in New Zealand ."} | [{"head": "Creutzfeldt - Jakob disease", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "human growth hormone", "tail_type": "", "tail_pos": []}] |
10db22d996f1801eccae4f9033a5e0f093f7a133292548e5460ae13cefa9524e | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "This eruption emerged after 1 month of therapy with salsalate , persisted for as long as salsalate was administered , and cleared within 3 weeks of discontinuing the medication ."} | [{"head": "eruption", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "salsalate", "tail_type": "", "tail_pos": []}] |
b83d61a1d4da49bbfa352dc3b0fc410153f936a075256b9ba41a19294eac5fa6 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A well - recognized complication of ethambutol use is optic neuropathy , but the potential ocular toxicity of isoniazid is often overlooked ."} | [{"head": "ocular toxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "isoniazid", "tail_type": "", "tail_pos": []}, {"head": "optic neuropathy", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ethambutol", "tail_type": "", "tail_pos": []}] |
5e89fb6fc7e998e1030f4c83bb049c00db24580e5d78cbc8eb6f6161ce044b15 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Skin necrosis after extravasation of low - dose vasopressin administered for septic shock ."} | [{"head": "Skin necrosis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "vasopressin", "tail_type": "", "tail_pos": []}] |
4d06f0d55f57e70f5364033db5fd411d299396382ded8b425756222b7ca94480 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "However , as the use of hepatitis B vaccination is growing , adverse side effects , including mental nerve neuropathy , should be observed with an increased frequency ."} | [{"head": "mental nerve neuropathy", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "hepatitis B vaccination", "tail_type": "", "tail_pos": []}] |
16b512f26a65d8df9c4f4dd68b372dc81603ce262f07445a232b3171d3669eea | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We conclude that MB is an effective treatment for ifosfamide - induced encephalopathy ."} | [{"head": "ifosfamide - induced encephalopathy", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ifosfamide", "tail_type": "", "tail_pos": []}] |
6dc87381873f971952790f40b8810fffd4c6638f442e710232eddbf94a82257c | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Prothipendylhydrochloride - induced priapism : case report ."} | [{"head": "priapism", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Prothipendylhydrochloride", "tail_type": "", "tail_pos": []}] |
b4abe768d82df07512b8bb2a70ac3fde62bd899bb1960f9574b8b33fe0e456b2 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Tacrolimus ( FK506 ) , an immunosuppressant , has been associated with mutism in adults after liver transplant ."} | [{"head": "mutism", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "FK506", "tail_type": "", "tail_pos": []}, {"head": "mutism", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Tacrolimus", "tail_type": "", "tail_pos": []}] |
4d2e4a6e6c2b4c2d3dc9acac0ea312861901462483be0d0d0057f55cb3b116ed | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Imidazoline intoxication due to overdose or accidental ingestion but also after normal therapeutic usage is frequent in children ."} | [{"head": "Imidazoline intoxication", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Imidazoline", "tail_type": "", "tail_pos": []}] |
b2732d7d02a7c9c5c045004a2a6eef5bd0de750b469605708b85ac93b75165a6 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Evaluation revealed elevated serum LTG levels and no other etiology for encephalopathy ."} | [{"head": "elevated serum LTG levels", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "LTG", "tail_type": "", "tail_pos": []}] |
845140e15cc6a44d50e31946126651101a7b301a3fa64f1a69a8ef6e9a3fbddd | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Central nervous system toxicity associated with meperidine use in hepatic disease ."} | [{"head": "Central nervous system toxicity", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "meperidine", "tail_type": "", "tail_pos": []}] |
0ceec208f7dafe436a69e2413c3fa73bfa47f88f900102423c45145386805c40 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Interferon - alpha - induced focal segmental glomerulosclerosis in chronic myelogenous leukemia : a case report and review of the literature ."} | [{"head": "focal segmental glomerulosclerosis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Interferon - alpha", "tail_type": "", "tail_pos": []}] |
043a70b82e1260218de737151adec025346f983ae5c6d74fafa927e857c4c42a | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "The patient developed occipital infarcts and was found to have extremely elevated levels of PPA in his blood and dialysis fluid ."} | [{"head": "extremely elevated levels of PPA", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "PPA", "tail_type": "", "tail_pos": []}, {"head": "occipital infarcts", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "PPA", "tail_type": "", "tail_pos": []}] |
99efa1da5044584caffbfc395b735eaa2db1e2a79cf6d05331b375a99e9c67aa | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "L - Thyroxine - induced leukopenia in a patient with Hashimoto 's disease : involvement of suppressor - cytotoxic T cells ."} | [{"head": "leukopenia", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "L - Thyroxine", "tail_type": "", "tail_pos": []}] |
cb64eefe7573fc91432191d03cd5da82229318ef6ac834cec9d3845d21a24880 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Amiodarone was the third drug to induce AVT in this patient ; she received 200 mg / day six days per week for six months ."} | [{"head": "AVT", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Amiodarone", "tail_type": "", "tail_pos": []}] |
5fd93a25032193db8b9e6863c78046e7772241f742225290e94ee52431e27451 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "This is a case of pseudoephedrine - induced intracerebral hemorrhage in a patient with an underlying vascular malformation ."} | [{"head": "intracerebral hemorrhage", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "pseudoephedrine", "tail_type": "", "tail_pos": []}] |
722e89e157d2d8b943c8b938adbc54717467ffd3b4e92ad52ebf70c0083d1d4e | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "A case of basilar invagination which is thought to have arisen from the patient 's intrauterine exposure to phenytoin is presented ."} | [{"head": "basilar invagination", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "phenytoin", "tail_type": "", "tail_pos": []}] |
8382d247310ce37f23a7482ab4a9cac3b6daceb5a65b410500deb40e124073bb | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "According to the Naranjo adverse drug reaction probability scale , tigecycline was the probable cause of her acute pancreatitis ."} | [{"head": "acute pancreatitis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "tigecycline", "tail_type": "", "tail_pos": []}] |
9577e02542d6f2f2feab74386530b2cce6fb58f3af35fb92201a5f199f1aa096 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "One type of SMON is associated with acrodermatitis enteropathica which has a very high frequency of occurrence in association with administration of clioquinol ."} | [{"head": "acrodermatitis enteropathica", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "clioquinol", "tail_type": "", "tail_pos": []}, {"head": "SMON", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "clioquinol", "tail_type": "", "tail_pos": []}] |
e81d00e3c67d071e434e8c86ff65122476bcc0c99bfb2250512619c2c3652549 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "We report the case of a 20-year - old woman originally from Cameroon who was infected by the L. loa parasite and developed severe hepatitis , identified 1 month after a single dose of ivermectin ."} | [{"head": "severe hepatitis", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "ivermectin", "tail_type": "", "tail_pos": []}] |
4f47c3545811b22bcfb3fe3b044000bc7abd26a2766edf9b09e3e5c331a09dab | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "Gabapentin withdrawal presenting as status epilepticus ."} | [{"head": "status epilepticus", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "Gabapentin", "tail_type": "", "tail_pos": []}] |
2ea65d3765e4f41f24bf0998cd51f356bb0baac26ceb53097ebac67171168905 | RE | ADE_corpus | {"instruction": "You are an expert in relationship extraction. Please extract relationship triples that match the schema definition from the input. Return an empty list for relationships that do not exist. Please respond in the format of a JSON string.", "schema": ["adverse effect"], "input": "However , follow - up revealed that gestational diabetes when associated with norethisterone had a lesser risk of emerging diabetes mellitus and impaired glucose tolerance ."} | [{"head": "diabetes mellitus", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "norethisterone", "tail_type": "", "tail_pos": []}, {"head": "gestational diabetes", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "norethisterone", "tail_type": "", "tail_pos": []}, {"head": "impaired glucose tolerance", "head_type": "", "head_pos": [], "relation": "adverse effect", "tail": "norethisterone", "tail_type": "", "tail_pos": []}] |