id
stringlengths 5
17
| title
stringlengths 2
2.56k
⌀ | abstract
stringlengths 3
29.9k
| type
stringclasses 4
values |
|---|---|---|---|
W2022384758 | Metastability and emergent performance of dynamic interceptive actions | Adaptive patterning of human movement is context specific and dependent on interacting constraints of the performer-environment relationship. Flexibility of skilled behaviour is predicated on the capacity of performers to move between different states of movement organisation to satisfy dynamic task constraints, previously demonstrated in studies of visual perception, bimanual coordination, and an interceptive combat task. Metastability is a movement system property that helps performers to remain in a state of relative coordination with their performance environments, poised between multiple co-existing states (stable and distinct movement patterns or responses). The aim of this study was to examine whether metastability could be exploited in externally paced interceptive actions in fast ball sports, such as cricket.Here we report data on metastability in performance of multi-articular hitting actions by skilled junior cricket batters (n=5).Participants' batting actions (key movement timings and performance outcomes) were analysed in four distinct performance regions varied by ball pitching (bounce) location.Results demonstrated that, at a pre-determined distance to the ball, participants were forced into a meta-stable region of performance where rich and varied patterns of functional movement behaviours emerged. Participants adapted the organisation of responses, resulting in higher levels of variability in movement timing in this performance region, without detrimental effects on the quality of interceptive performance outcomes.Findings provide evidence for the emergence of metastability in a dynamic interceptive action in cricket batting. Flexibility and diversity of movement responses were optimised using experiential knowledge and careful manipulation of key task constraints of the specific sport context. | publication |
US 2014/0028695 W | GATE VALVE ASSEMBLY COMPRISING A SUPPORT MEMBER | A gate valve assembly having a through bore adapted for fluid communication with a well bore and prepared for receiving an elongated member. The gate valve assembly comprises a gate element which is movably arranged in a gate valve housing, wherein the gate element has a gate bore arranged for receiving the elongated member, wherein a cutting tool is arranged in the gate bore first and second seats, wherein at least one of the first or second seat is arranged to provide sealing contact with a sealing surface of the gate element. A support member arranged with an opening encompassing the through bore and an expanded opening portion which is open to the through bore in the axial direction of the through bore, wherein a reduced section of the support member defines the expanded opening portion, and the opening has a decreasing radius along the reduced section in the axial direction of the support member toward a contact surface area arranged at an end portion of the support member adjacent the cutting tool, wherein the radius of the opening corresponds essentially to the radius of the through bore. The contact surface area is prepared for engagement with the elongated member and provides a counter acting area interacting with the cutting tool when shearing the elongated member. The invention also includes a method. | patent |
US 2016/0041844 W | SURGICAL INSTRUMENT AND METHOD OF USE | A surgical instrument includes an element connectable with a fixture. A first member is independently and selectively movable relative to the element and includes a part engageable with an incision in a cranial-caudal orientation relative to a body to space apart tissue. A second member is independently and selectively movable relative to the element and includes a part engageable with tissue of an anterior portion of the incision relative to the body. A third member is independently and selectively movable relative to the element and includes a part engageable with tissue of a posterior portion of the incision relative to the body. Systems and methods are disclosed. | patent |
W2125068452 | Market Power in an Exhaustible Resource Market: The Case of Storable Pollution Permits | Motivated by the structure of existing pollution permit markets, we study the equilibrium path that results from allocating an initial stock of storable permits to an agent, or a group of agents, in a position to exercise market power. A large seller of permits exercises market power no differently than a large supplier of an exhaustible resource. However, whenever the large agent's endowment falls short of his efficient endowment – allocation profile that would exactly cover his emissions along the perfectly competitive path – market power is greatly mitigated by a commitment problem, much like in a durable-goods monopoly. We illustrate our theory with two applications: the US sulphur market and the international carbon market that may eventually develop beyond the Kyoto Protocol. | publication |
169966 | Genetic and molecular priming approaches to increase crop strength and stress tolerance | The project provides advanced systems biology training for 5 ESRs who will develop novel methods for increasing crop strength and resistance to stress by alternative genetic and genomic, non-GMO, technologies: (1) Selecting allelic variants of a novel gene identified by members of the consortium which regulates oxidative and abiotic stress tolerance and (2) Molecular priming by biostimulants or low doses of H2O2 to induce stress-protective mechanisms in crops. This dual approach will meet the growing EU push towards secure, sustainable and safe means of food production (Dir.2009/128/EC & EU Reg. EC/178/2002). The genetic approaches are combined with high-throughput technologies for transcriptome, metabolome, and phenotypic analyses, combined with advanced bioinformatics. Both approaches to increasing crop yield are growing in importance, with the biostimulants industry expected to reach $2.2B globally by 2018. Equipping ESRs with these skills will enable them to develop their research careers in academia or industry. Training will be conducted at the University of Potsdam (UP, Coordinator), Germany, and two companies: BioAtlantis (BA), Ireland, and Enza Zaden (EZ), The Netherlands. Prof. B. Mueller-Roeber (UP) has extensive research management and teaching experience and will supervise the ESRs as PhD students. BA is internationally recognized for producing innovative biostimulants and has 3 patents filed, while EZ is among the top ten in vegetable breeding worldwide. All partners have experience in coordination and participation in EU FP7 projects. The expected results will increase our understanding of the molecular basis of stress tolerance and provide two alternative strategies for crop improvement and increasing food production. BA and EZ will ensure rapid dissemination of applied research to end users. | project/european |
894884 | Wearable applications enabled by electronic systems on paper | The WASP project aims at bringing the much-needed step change in flexible and wearable electronics by developing a new industrially driven enabling printing technology for the definition of electronic devices and circuits on paper, a flexible and foldable substrate, which is low cost, disposable, biodegradable, easily obtainable in nature and compatible with high speed roll-to-roll processes. The proposed technology is based on an environmentally friendly process and addresses the needs for future circular economy, as well as that for cheap, flexible and lightweight, multi-functional electronics. At the end of the project, a demonstrator will be released, able to sense biometric parameters (i.e., humidity, pH, glucose levels) and to communicate to an external reader, developed on purpose within the WASP activity. | project/european |
W2746381864 | Plan de mejora de atención al cliente en Recaudaciones del Gobierno Autónomo Descentralizado de la Provincia de Pichincha | The collection of taxes in the public sector has always been colored by the chaos that is
almost always generated in the institutions where these collections are made, the GAD
case of the Province of Pichincha has not escaped this reality and it is in this problem,
That this investigative work is developed trying to give solution to this constant
agglomeration of people and of long rows for his attention.
In this study a descriptive type investigation was carried out of the current situation of
the office in question, the historical - logical method was used to determine in time how
this problem has been happening and the survey was helped as the main source of
information in the search for solutions.
From the study carried out and with the strategies of improvement raised a considerable
reduction in the times of collections towards the users of this dependence.
Keywords: improvement, collection, taxes, customer service. | publication |
US 9506343 W | FIBERS AND FABRICS INCORPORATING LOWER MELTING PROPYLENE POLYMERS | Propylene homopolymers and copolymers formed by metallocene catalyst system exhibit generally lower melting behaviour than previous propylene polymers. This lower melting behaviour will be of use in the fabrication and use of fibers and fabrics that depend upon either lower melting behaviour in general or upon a melting point differential between two fabrics or fibers to achieve bonding. Such fibers are, for instance, chenille or tufted cord, core and sheath. Fabrics such as spunbonded and meltblown, when combined in SM or SMS fabrics will show bonding at lower temperatures with fewer pinholes. Such fabrics may also be bonded by adhesives such as hot melt, water based and extruded polyolefins. Combinations of Ziegler-Natta catalyzed and metallocene catalyzed polymers are contemplated. | patent |
W1587724255 | ESTUDIO EMPÍRICO SOBRE LA UTILIZACIÓN DE LA ESPECIFICACIÓN 2000M EN CADENAS DE SUMINISTRO DE AERONAVES MILITARES | The automation of the commercial transactions among the customers and suppliers involved in a supply chain allows its efficient and effective management. Such automation is based on the utilization of Electronic Data Interchange protocols and this paper reports the results of an empirical and exploratory research on the use of the protocol known as Specification 2000M (S2000M) in the Information Systems (IS) supporting supply chains for military aircraft. The research is based on questionnaires from 62 persons in 9 European nations working in areas related with the subject under study. This document proposes a model to implement supply chains based on the S2000M-based, and identifies the benefits delivered by the S2000M, the level of success of the S2000M-based IS, the benfits that impact the most such success and some measures to gauge the performance of the S2000M systems. | publication |
628615 | Integrated open access materials modelling innovation platform for europe | OpenModel provides an integrated open access material modelling platform designed to be easily integrated with, and usable by, any existing and future EU platforms, e.g., Open Translation Environments (OTE), Materials Modelling Market Places (MMMP), Innovation Test Beds (ITB), and Business Decision Support Systems (BDSS). Furthermore, OpenModel integrates with Life Cycle Analysis as well as the ""plug and produce"" and characterization open innovation environments to enable better integration of characterization and processing into materials modelling workflows. The OpenModel platform directly addresses the needs of industry for creating and executing standardised advanced materials modelling workflows by offering 5 main ingredients: 1) EMMO based ontology extensions as basis for all developments, 2) An Interoperability layer providing an implementation of EMMO-based Common Universal Data Structures classes (CUDS) for describing any modelling workflow or simulation data in a semantic manner, 3) An Open Simulation Platform based on standardised interfaces and semantic common application programming interfaces (API), to enable integration of third party physics based modelling codes, 4) Smart workflow builders that respond to semantic information and requirements from OTE, MMMP, ITB, and BDSS and creates on the fly advanced workflows taking into account Key Business and Technical Performance Indicators (KPI) utilising the semantic power embedded in the platform, and 5) workflow executors and curators able to perform and manage the results making it readily and transparently available for further control and processing by the other platforms. OpenModel targets multiple use cases and materials with their processing in the fields of environment, aviation and automotive industry, yet OpenModel's scope is generic and can thus address all materials modelling, processing and characterization fields. OpenModel is the platform for materials modelling Services in Europe. | project/european |
EP 12192909 A | Catheter and catheter arrangement | The catheter (10) has an elongated catheter body (13) comprising a distal end (10d) and a proximal end, where the catheter is designed as an electrode line. A sponge or cushion-like elastic deformation body is arranged at the distal end, and has an electrically, mechanically or optically-acting measuring unit or measuring connection to detect pressing force exerted on the body. The body contains plastic foam with electrically-conductive polymer or with particles made of ferroelectric film, or fluid e.g. liquid, gel or filling of pourable particles. The catheter is provided with a stimulation and/or sensing electrode that is made of conductive plastic. | patent |
interreg_3059 | ROMAN ITINERARIES | The travelling public's growing interest in archaeology is a typical example of what is often referred to as "motivation tourism", a set of new market segments opposed to "generic tourism". The main challenge of the ROMIT project is to find new ways of preservation and management for Roman archaeological complexes to integrate them into local development policies. The aim is to protect the heritage in an area embracing cities of Roman origin situated in Emilia-Romagna, Bavaria and Western Greece, and also to create employment and foster regional development through an intelligent enhancement of the cultural resources, with special benefits for the institutions, local actors and populations of the involved territories. The ROMIT project covers two major lines of action: a thorough research action aimed at comparing the management systems of the involved sites, identifying their weaknesses, successes and potentials, and drafting and testing transnational public/public and public/private co-operation models for the development planning of archaeological sites which facilitate their integration into the regional and local policies. | project/regional |
646003 | Crop production in the levant and international trade exchange: investigating coprolites and crop plant remains from the 1st millennium ce negev highlands and aravah valley | CroProLITE aims to evaluate the Islamic Green Revolution (IGR) thesis–involving crop introduction from eastern and central Asia to the Mediterranean by Early Islamic empires–through a microregional comparative study of 1st millennium CE agropastoral change. It applies archaeobotanical and biomolecular methods to numerous well-preserved plant macrofossils and herbivore dung pellets from rubbish dumps at nine Roman-Early Islamic trading sites in the Aravah valley on the southern border of modern Israel-Jordan and the adjacent Negev Highlands. Some sites are associated with Early Islamic agrotechnological introduction of qanat irrigation, indicating likely Early Islamic crop introduction there. Capitalizing on similarity of archaeological context alongside dissimilarity of historic-economic context, the comparative method will be applied to these regions and periods. To identify seasonal agropastoral rhythms, an extensive and innovative multi-proxy methodological study will analyse contents of ancient dung pellets from the sites. New datasets generated from plant remains and coprolites will allow synthesis of agropastoral developments at seasonal to millennial scales and framing of findings in terms of ancient economic history and Mediterranean deep history. Lessons on agricultural continuity and change from the Negev-Aravah in the face of first millennium CE global climate change, plague and cultural conflict hold promise for improved understanding of historical effects of environmental stressors. In unearthing such lessons, CroProLITE will contribute to long-term environmental risk assessment and reflection on our own society’s future, offering a model for environmental humanities research.
Host supervisor and leading palaeoproteomics scholar Matthew Collins will guide biomolecular archaeology training through coprolite analysis, alongside multiple mentors for ancient economic history and Mediterranean history-archaeology, including career mentor Cyprian Broodbank. | project/european |
3726270 | Enhancing and strengthening the excellence in interdisciplinary biomedical research at transcend | TRANSCEND, designed as a translational research centre at the Regional Institute of Oncology (IRO), an university hospital, due to the EU Structural Funds, is in a emergent stage of its development. The centre, planned to generate a translational repertoire of biomarkers capable to develop the diagnostic tumor taxonomy and to keep going the personalized therapy, was founded on the interdisciplinary interplay between several cell and molecular high-throughput technologies. It therefore offers a stimulating and dynamic scientific and clinical environment to reach its maximum potential by extending the current scientific aims to a more pronounced inter-, multi- and transdisciplinary approach of the biomedical research. Such a goal will be fulfilled by exploring the huge opportunities brought by nanomedicine in development of less expensive and more powerful devices and functionalized nanocarriers used for the diagnosis and treatment of human diseases. Hence, the ambitious goal of the ESEI-BioMed project is to enhance and strengthen the excellence of the interdisciplinary biomedical research at the TRANSCEND research centre. To meet this objective, a highly successful and experienced leadership (ERA Chair holder) whose experience and professional value, including a range of skills from excellent research manager to excellent researcher in the field of nanomedicine-oriented research, will be hired aiming at implementing positive changes in the actual organization of the centre. The interdisciplinary scientific plan and the management skills of the ERA-Chair holder will certainly be the catalysts of the creation of an interdisciplinary team made of highly-skilled and dedicated researchers capable to properly address the scientific challenges and finally to increase the international visibility, translational capability and socio-economic impact of the TRANSCEND. | project/european |
W1538555780 | Otolith and vertebral morphology of marine atherinid species (Atheriniformes, Atherinopsidae) coexisting in the southwestern Atlantic Ocean | Studies on marine ecosystems rely on the identification of fish prey species of piscivores (fish, aquatic mammals, and aquatic birds) based on their bones and otoliths. The stomach contents of piscivores show predation on marine atherinids of commercial value; however, their identification is difficult due to the coexistence of these species. The objective of the present study is to propose the use of hard structures (otolith, caudal vertebrae) as a tool for the identification of marine atherinid fishes occurring in the southwestern Atlantic Ocean. Sagittae (200 pairs) were removed from the otic capsules for further examination and measurement. The vertebral column of individuals from each species was also removed for examination. The morphological pattern of the sagitta otoliths of five marine species belonging to the genus Odontesthes was consistent with that of the subfamily Atherinopsinae, with these patterns being species specific. In Odontesthes argentinensis, O. platensis, and O. smitti, the caudal vertebrae present an expansion of the haemal arch walls forming a haemal funnel with distinctive morphology, while this characteristic is absent in O. incisa and O. nigricans. The hard structures used in this study proved to be a useful tool for the correct identification of the atherinids found in the diet of piscivorous species from the southwestern Atlantic Ocean. A key based on the major morphological features of sagittae and hemal arches is provided. | publication |
Q2716727 | Entwicklung innovativer Technologie zur Rückgewinnung von Phosphor aus kontaminierten natürlichen Gewässern für landwirtschaftliche Zwecke unter Verwendung mineralischer Zuschlagstoffe | Der Umfang der Investition besteht in der Durchführung von Industrie- und Entwicklungsforschung auf dem Gebiet der Entwicklung der Phosphorrückgewinnungstechnologie aus kontaminierten natürlichen Gewässern für landwirtschaftliche Zwecke. Die Investition wird in der Stadt Bartąg bei ul. Nad Łyna 14 B. Drei Phasen der Forschung sind für das Projekt geplant. Zwei von ihnen werden als Entwicklungsforschung und eine als Entwicklungsarbeit qualifiziert.Der Antragsteller beabsichtigt, eine innovative Technologie zur Rückgewinnung von Phosphor aus kontaminierten Gewässern für landwirtschaftliche Zwecke zu entwickeln. Diese Investition steht im Einklang mit den Annahmen des SzOOP RPO WiM für Prioritätsachse 1 Intelligente Wirtschaft von Warmia und Mazury für Maßnahme 1.2.- Innovative Unternehmen, 1.2.1 – FuE-Tätigkeiten von Unternehmen und ist mit dem wichtigsten thematischen Ziel 1 identisch. Stärkung von Forschung, technologischer Entwicklung und Innovation. Typ 2 Forschung in Unternehmen (industrielle Forschung und/oder Entwicklung), einschließlich Investitionen in materielle und immaterielle Vermögenswerte zur Entwicklung oder Modernisierung der Forschungsinfrastruktur zur Durchführung marktorientierter FuE-Tätigkeiten (z. B. Investitionen in Pilotlinien, Ausrüstungen und Ausrüstungen, die für Demonstration, Validierung, Erprobung im Rahmen eines größeren FuE-Projekts erforderlich sind). | project/regional |
W3016714088 | Characterization of Nonstationary Phase Noise Using the Wigner–Ville Distribution | Oscillators and atomic clocks, as well as lasers and masers, are affected by physical mechanisms causing amplitude fluctuations, phase noise, and frequency instabilities. The physical properties of the elements composing the oscillator as well as external environmental conditions play a role in the coherence of the oscillatory signal produced by the device. Such instabilities demonstrate frequency drifts, modulation, and spectrum broadening and are observed to be nonstationary processes in nature. Most of the tools which are being used to measure and characterize oscillator stability are based on signal processing techniques, assuming time invariance within a temporal window, during which the signal is assumed to be stationary. This letter proposes a new time-frequency approach for the characterization of frequency sources. Our technique is based on the Wigner–Ville time-frequency distribution, which extends the spectral measures to include the temporal nonstationary behavior of the processes affecting the coherence of the oscillator and the accuracy of the clock. We demonstrate the use of the technique in the characterization of nonstationary phase noise in oscillators. | publication |
W2246391972 | Numerical simulations of axisymmetric hydrodynamical Bondi–Hoyle accretion on to a compact object | Bondi-Hoyle accretion configurations occur as soon as a gravitating body is immersed in an ambient medium with a supersonic relative velocity. From wind-accreting X-ray binaries to runaway neutron stars, such a regime has been witnessed many times and is believed to account for shock formation, the properties of which can be only marginally derived analytically. In this paper, we present the first results of the numerical characterization of the stationary flow structure of Bondi-Hoyle accretion onto a compact object, from the large scale accretion radius down to the vicinity of the compact body. For different Mach numbers, we study the associated bow shock. It turns out that those simulations confirm the analytical prediction by Foglizzo & Ruffert (1996) concerning the topology of the inner sonic surface with an adiabatic index of 5/3. They also enable us to derive the related mass accretion rates, the position and the temperature of the bow shock, as function of the flow parameters, along with the transverse density and temperature profiles in the wake. | publication |
interreg_1079 | Biblioteca Naturale in rete della cultura scientifica, tecnica e naturalistica del Medio-Alto Tirreno | E-pistemeTec involves the construction of a thematic digital library (DL) on the interactive and multilingual heritage of science, technology and natural common areas of the Middle-Upper Tyrrhenian Sea.
The reference area includes the north of Corsica, the area of Liguria, Tuscany and Sardinia in the south Tyrrhenian, but the impact of the project include the entire area of the target program.
E-pistemeTec intends to exploit the potential of Web 2.0 and the latest digital technology, with informational purposes, safeguards, joint research and development.
Main target groups are: institutions for the protection and enhancement of the library, archive and museum, teachers and students in schools and universities, scholars, but also pro-spot, tourists and citizens, including disabled.
Main action: Step 1: Mapping of documentary sources of culture scientific-technical policy, selection and digitization work on a historical-scientific criteria and priorities for conservation;
Step 2: creation of interactive Web site E-pistemeTec for the use of items scanned, and access to the community (e-books, turning the pages, viewing 3D objects, virtual tours, bibliographic and historical background, cultural, social tools networking);
Step 3: creation of a permanent network (intranet and internet) between the project partners and other institutions, schools, companies and cultural foundations, museums, provision of training courses in e-learning;
Step 4: implementation of events, promotion to outside parties.
| project/regional |
W2593668362 | The effect of compression ratio on the performance and emission characteristics of a dual fuel diesel engine using biomass derived producer gas | Abstract The emission level produced from agriculture waste during wheat and paddy harvesting season causes an environmental disturbance in many states of India. In the present work, the performance and emission characteristics are studied by using downdraft gasifier and direct injection variable compression diesel engine. Besides emission characteristics, diesel replacement and noise level at different loads and compression ratios were also estimated. It was observed that maximum diesel saving attained was 8.7%, 31.82%, 57.14% and 64.3% at a compression ratio 12, 14, 16 and 18 respectively. An average reduction of 63.62% in HC emission was achieved by increasing the compression ratio from 12 to 18 at 3.2 kW brake power. With dual fuel mode NOx emission was reduced (in the range 35.29–56.09% for different conditions) as compared to diesel fuel mode. Further, the SOx emission levels were up to 45.45% less in the dual fuel mode. | publication |
W2273186728 | Structural power and the global financial crisis: a network analytical approach | How did the most severe global financial crisis since the 1930s affect the organization of the world political economy? Was Anglo-American structural power in finance eroded? I employ network methodologies that have been recently extended for use with weighted and directed networks to shed light on these questions. I draw from complexity science and political economy to link these empirics to prior theories of structural power, which I refine in several ways. This approach provides unique explanations for developments in global banking since the crisis, including expected outcomes that did not occur: the continuation – and even expansion – of Anglo-American prominence, the decline of continental European prominence, and the lack of emergence of the BRICS economies into the core of the global banking system. | publication |
GB 3290545 A | Improvements in or relating to wicks | 600,537. Wicks. POWER, J. K., (formerly POSNER, K.). Dec. 5, 1945, No. 32905. [Class 75(i)] To facilitate the insertion of a wick in a cigarette or like lighter a pull member 4 of metal wire or fibrous or plastic thread is attached to the wick by plastic material 2. The material may be secured to the wick by a solvent such as acetone, glue, or by heat and pressure. In a modification the free end of the plastic material 2 forms the pull member. | patent |
W2363380059 | The Decline and Reconstruction of Cultures——Albert Schweitzer′s Opinions on Modern Cultures | According to Albert Schweitzer,compared with the Enlightenment culture and rationalistic culture,the western culture experienced a decline in the end of 19th century and the beginning of 20th century.He believed that this decline was due to the impediments of the material to the spiritual which led to the disappearance of ethical essentials in a culture.In his opinion,if westerners want to revive or reconstruct western culture,they should build up a world view which could carry the ethical ideal of a culture,that is,reverence for life.Since the development of Chinese culture is at the critical moment,it is time to think over our culture strategies.And a lot can be learned from Albert Schweitzer′s theory. | publication |
W2242780651 | Torrefied biomasses in a drop tube furnace to evaluate their utility | Torrefaction and burning characteristics of bamboo, oil palm, rice husk, bagasse, and Madagascar almond were studied and compared with a high-volatile bituminous coal using a drop tube furnace to evaluate the potential of biomass consumed in blast furnaces. Torrefaction at 250 and 300 C for 1 h duration was carried out. Analysis using the ash tracer method indicated that the extent of atomic carbon reduction in the biomasses was less than that of atomic hydrogen and oxygen. Torrefaction also lowered the sulfur content in bamboo and oil palm over 33%. An examination of the R-factor and burnout of the samples suggests that more volatiles were released and a higher burnout was achieved with raw and torrefied biomasses at 250 C than at 300 C; however, torrefaction at 300 C is a feasible operating condition to transform biomass into a solid fuel resembling a high-volatile bituminous coal used for blast furnaces. 2012 Elsevier Ltd. All rights reserved. | publication |
interreg_2060 | Local Initiative STrENgthening: how to build up a new TOurism in THE Valleys and among the mOst vItal CEntres OF rural VILLAGES | For several years rural areas have been suffering from big difficulties and troubles occurred in the competitiveness, the attractiveness and the unemployment field. A problem which is typical for many Central Europe areas, characterized by marginality problems depopulation, demographical changes due to a progressive ageing of local population along with a deep lack and inadequacy of the territorial development policies.
Nevertheless the territories in question are in possession of enormous natural, cultural-historical and local craft wealth. These resources, if properly exploited, could become the real “economic engine” of these areas. The main goal of the project is to consequently increase the competitiveness and the attractiveness of these rural marginal territories, showing unexpressed tourist potential, through the settlement and the implementation of new territorial governance tools and implementing new pilot projects inside the sustainable tourism sector. | project/regional |
W2010056296 | Feasibility of the P- and S-beam methods for stability estimation of the Daegok dam in Korea | We investigate the feasibility of using the P- and Sbeam seismic methods to evaluate the stability of dams, employing these methods to analyze the Daegok dam in Korea (a concrete faced rockfill dam; CFRD). In the beam method, adjacent shot gathers are stacked to generate super shot gathers, which can be similar to those obtained using a group of shots or groups of geophones. In the super shot gathers, surface waves and unwanted noises may be suppressed due to phase shifts that occur at adjacent shot gathers, whereas deep reflection events with slight phase differences may be enhanced. For this reason, deep reflection events can be better imaged than shallow ones. By applying the P- and Sbeam methods to the Daegok dam, we were able to image the interior structures of the dam and determine physical properties such as velocities and the Poisson’s ratio. Compared with the velocities obtained from borehole P-S logging for other rockfill dams, the velocities and Poisson’s ratio obtained for the Daegok dam are reasonable. Given that a strong source generator cannot be used with dams because it might damage them, we feel that the P- and S-beam methods can be effective means of evaluating dam safety. | publication |
interreg_1848 | IONian Integrated marine Observatory | The project aims at designing and implementing an Ionian Integrated Marine Observatory that will produce environmental information about the Southern and Northern Ionian Programme Area to support safer maritime traffic and the reduction of pollution hazard. In particular the partners will develop: • An information system (IS) for the observations and model analysis and forecasts to be accessed in real time with Web-based Portals containing discovery, visualization and downloading services (INSPIRE compliant) • The applications, in terms of Decision Support System-DSS, deriving from these products for Ship Routing and Safety (SRS), Search and Rescue (SAR), Pollution Hazard Management (PRM) for transport routes across the area • Test and evaluate the different DSS with regional stakeholders from the transport industry, coast guards, port authorities, environmental protection agencies and the civil protection. | project/regional |
W2593592732 | ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI PEMBIAYAAN BERBASIS BAGI HASIL PADA PERBANKAN SYARIAH DI INDONESIA PERIODE 2010-2014 | Islamic banking is a financial institution that serves as an intermediary between the parties that have surplus funds and those who need funds. As intermediary institution, Islamic bank perform its role by channeling funds for financing. There are several products of financing that provided by Islamic bank, one of them is profit and loss sharing based of financing. The attempt of Islamic bank in channeling its funds for financing was not apart from the risks, therefore good management and control are needed. Islamic bank should observe the factors that may affect on financing. The purpose of this study was to analyze the factors that influence profit and loss sharing based of financing of Islamic bank. The population in this study was Islamic commercial banks in Indonesia, which consists of 12 banks. The samples used are selected using purposive sampling technique and there are 4 banks that meet the criteria. The data used in this study are secondary data that obtained from quarterly financial reports of Islamic bank during the period of 2010-2014, and the number of observation points is 100. The method of data analysis used in this study is multiple linear regression analysis with significant level of 5%. The results showed that simultaneously, the five independent variables include equivalent rate, FDR, CAR, NPF, and SWBI are significantly influence to profit and loss sharing based of financing. Partially, SWBI has positive significant effect on profit and loss sharing based of financing and CAR influence significantly negative to profit and loss sharing based of financing, while equivalent rate, CAR and NPF didn’t influence to profit and loss sharing based of financing. Result of regression estimation show that the predictive ability of the model was 70.2%, while the remaining 29.8% was influenced by other factors outside the model. | publication |
W2015466846 | Developing the Serious Games potential in nursing education | Shortened hospital stays, high patient acuity and technological advances demand that nurses increasingly make decisions under conditions of uncertainty and risk (Ebright et al., 2003). With rising trends towards out-patient care, nurses will need to perform complex problem-solving within a dynamic and changing environment for which there is not one clear solution (Schofield et al., 2010; Wolff et al., 2009). The development of sharp clinical reasoning skills, as well as skills in detection, monitoring, investigation and evaluation are therefore essential (Aitken et al., 2002). Yet few nursing students have long-term exposure to home-care and community situations. This is primarily due to scarce human resources and the time-consuming requirements of student supervision (Duque et al., 2008). When students are given the opportunity to experience home-care or community visits these tend to be unstructured leading to wide variations in their competencies. New pedagogical tools are needed to adequately and consistently prepare nurses for the skills they will need to care for patients outside acute care settings. Advances in Information and Communications Technologies (ICT) offer an opportunity to explore innovative pedagogical solutions that could help students develop these skills in a safe environment. A three-phased project is underway that aims to create and test a Serious Game to improve nurses' clinical reasoning and detection skills in home-care and community settings. The first phase of this project involves the development of a scenario, the game engine and the graphic design and will be the focus of this paper. The second and third phases will test the Serious Game as an educational intervention and will be reported in subsequent papers. | publication |
2728463 | Rational design of cancer immunotherapy: one size does not fit all | Checkpoint blockade immunotherapies have revolutionized cancer treatment. However, this immunotherapy only benefits a minority of patients (< 15%), mainly those diagnosed with cancers having many mutations. Furthermore, checkpoint blockade therapy does not selectively activate cancer-reactive T cells.
RARITY responds to these shortcomings, aiming to provide innovative solutions for the development of effective immunotherapies for patients who do not benefit from current treatments. The ground-breaking preliminary data included in this application demonstrates that cancer-reactive T cells can be naturally present in so-called non-immunogenic cancers and that they acquire distinctive phenotypes. RARITY will apply state-of-the-art technologies to fingerprint these phenotypes. This will allow the isolation of cancer-reactive T cells from tumour tissues and their employment as highly-effective therapies. Therapeutic vaccination with cancer antigens can also be used to induce T cell responses in patients where natural activation of cancer-specific T cells is not detectable. However, the applicability of vaccination is compromised by the lack of specific targets, particularly in malignancies with few mutations. RARITY will address this problem by deploying a novel class of cancer antigens. An unprecedented screening of non-exomic genomic regions will be done to detect unannotated proteins that arise from de novo transcription and translation events. These proteins can then be targeted by personalized immunotherapies. Finally, thought-provoking findings included in RARITY suggest that immune cell subsets other than T cells play a major role in anti-tumour immune responses. These subsets need to be fully inventoried and categorised so that complementary strategies to T cell immunotherapies can be developed. RARITY will do so by conducting multidimensional analysis of cancer microenvironments using imaging mass cytometry and ex vivo modulation of immune responses. | project/european |
US 2012/0052185 W | ASYMMETRIC RADIAL SPLINE SEAL FOR A GAS TURBINE ENGINE | A shroud apparatus for a gas turbine engine includes: an annular shroud segment (26) having an arcuate bottom wall (52) defining an arcuate inner flowpath surface(62), spaced-apart forward and aft walls (54, 56) extending radially outward from the bottom wall (52), and spaced-apart side walls (58) extending radially outward from the bottom wall (52) and between the forward and aft walls (54, 56), each side wall (58) defining an end face (74) which includes: an axial slot (76) extending in a generally axial direction along the end face (74); a first radial slot (78) extending in a generally radial direction along the end face (74), and intersecting the axial slot (76); an axial spline seal (82) received in the axial slot (76); and a first radial spline seal (84) having an L-shape with radial and axial legs (88, 90), the radial leg (88)being substantially longer than the axial leg (90), wherein the radial leg (88) is received in the first radial slot (78), and the axial leg is received in the axial slot (76). | patent |
W2281320412 | Simulation, model‐reduction, and state estimation of a two‐component coagulation process | The issue of state estimation of an aggregation process through (1) using model reduction to obtain a tractable approximation of the governing dynamics and (2) designing a fast moving-horizon estimator for the reduced-order model is addressed. The method of moments is first used to reduce the governing integro-differential equation down to a nonlinear ordinary differential equation. This reduced-order model is then simulated for both batch and continuous processes and the results are shown to agree with constant Number Monte Carlo simulation results of the original model. Next, the states of the reduced order model are estimated in a moving horizon estimation approach. For this purpose, Carleman linearization is first employed and the nonlinear system is represented in a bilinear form. This representation lessens the computation burden of the estimation problem by allowing for analytical solution of the state variables as well as sensitivities with respect to decision variables. © 2016 American Institute of Chemical Engineers AIChE J, 62: 1557–1567, 2016 | publication |
W2207278958 | Macau: Large-scale skill sense disambiguation in the online recruitment domain | Named entity sense disambiguation is a problem with important natural language processing applications. In the online recruitment industry, normalization and recognition of occupational skills play a key role in linking the right candidate with the right job. The disambiguation of multisense skills will help improve this normalization and recognition process. In this paper we discuss an automatic large-scale system to identify and disambiguate multi-sense skills, including: (1) Feature Selection: employing word embedding to quantify the skills and their contexts into vectors; (2) Clustering: applying Markov Chain Monte Carlo (MCMC) methods to aggregate vectors into clusters that represent respective senses; (3) Large-scale: implementing parallelization to process text blobs on a large-scale; (4) Pruning: cluster cleaning by analyzing intra-cluster cosine similarities. Based on experiments on sample datasets, the MCMC-based clustering algorithm outperforms other clustering algorithms for the disambiguation problem. Also based on data-driven in-house evaluations, our disambiguation system achieves 84% precision. | publication |
220206 | Triggering haematological adoptive t-cell immunotherapy strategies by hunting novel t-cellreceptors | Recent encouraging clinical results obtained with engineered T lymphocytes and increasing advances in the genome editing field, have opened new opportunities for T-cell receptor (TCR) gene therapy as an immunotherapeutic approach for cancer.
Unfortunately, the broad applicability of this treatment is still hampered by the possible mispairing of exogenous/endogenous TCR chains and by the limited number of high avidity tumor-specific TCRs. While the first issue has been successfully addressed by the hosting lab with the development a TCR gene editing protocol, the identification of novel tumor-specific TCRs is urgently required and this is the aim of my research proposal. We have the unique opportunity to combine the highly complementary expertise of the hosting lab in T-cell biology/genetic transfer and of the applicant on immune repertoire sequencing. We will target acute myeloid leukemia (AML) and hypothesize that by exploiting intrinsic features of AML (i.e. ability of AML blasts to differentiate into potent antigen presenting cells expressing tumor antigens), the functional fingerprint induced by AML on tumor-reactive T-cells, and cutting-edge technologies (i.e. next generation sequencing; ligandome landscape analysis), we will provide a comprehensive immunoprofiling of tumor-specific T-cells and isolate tumor TCR specificities. Results obtained in this study will streamline TCR hunting studies in solid tumors, leading to the generation of a TCR library for different antigens and HLA restrictions, thus rendering TCR gene editing an innovative off-the-shelf treatment available for a high number of cancer patients. Awarding this fellowship will greatly enhance researcher’s career not only by providing the opportunity to widen scientific knowhow and acquire new skills, but also by enabling the researcher to address a major bottleneck currently limiting the full exploitation of the rapidly growing field of cancer immunotherapy. | project/european |
223675 | Democratic participation in territorial states | Who should have a right to participate in the making of political decisions? Political theorists have thus far approached this important moral question in two ways. Theorists of territorial rights argue that the right to make laws on particular territories belongs to groups, such that a person’s enfranchisement derives from her group membership. In contrast, democratic theorists argue that states should enfranchise anyone affected or subjected by their laws, regardless of group membership; if not, their lawmaking is undemocratic. This creates an intriguing dilemma. As they stand, the prominent theories preclude a straightforward dual commitment to democratic decision-making and collective territorial rights: we must either give non-members a say over a group’s lawmaking on ‘its’ territory, or withhold various individuals’ right to a democratic say.
DEPART solves this impasse. It will conduct the first systematic exploration of how theories of territorial rights and democratic participation may be plausibly combined, and thus develop a unified theory of rights of democratic participation (through voting) in territorial states. The project will use what is known as the method of reflective equilibrium – a common methodology within the Anglo-American (or ‘analytical’) tradition of normative political theory/political philosophy.
DEPART will achieve several valuable goals. First, by showing how insights from apparently disparate approaches may pull in the same direction, its unified theory gives a promising framework for fruitful future research on territorial rights and democratic participation. Second, it gives policy-guidance on several issues on the EU agenda, including whether EU citizens living in another member state should have a say in that state’s national elections – an issue recently raised by the Commission. Third, when communicating its action and results, it reinforces public awareness of the value of democratic participation (especially among youths). | project/european |
W2104853922 | Volunteer activity in end–of-life care: a national survey of current practice | Introduction Specialised end-of-life care supports patients and families during the last months of life and, in the UK, is commonly provided either in a hospice or in a patient9s home. Demand for such care in the UK will increase with mortality rates predicted to rise from 2012 to 2030 by 17%. The precise number and contribution of volunteers is unknown. However, it is estimated that there are over 100,000 volunteers working in UK hospices and that their contribution reduces costs by around 25%. The current economic situation is likely to limit funding. This means it is essential that we understand where volunteers are currently deployed to enable planning to be based on real practice. Aims and Methods Focusing on volunteers in direct contact with patients and families this survey seeks to establish the extent of volunteer activity in UK end-of-life specialised care. A web-based nationwide survey of end-of-life care organisations, targeted at over 200 managers of volunteer services, including managers of hospices and home care teams. Results The results, which will be available, will be analysed using descriptive statistics. They will give an overview of volunteer involvement in supporting patients and families in end-of-life care, detailing aspects volunteers are involved in and establishing which services are often volunteer-led. Conclusion This will be the first UK-wide survey of its kind. It will highlight where further evaluation and development should be focused. | publication |
US 63494106 A | Method for realizing route forwarding in network | A method for realizing route forwarding in a network, including: establishing LSPs in a bearer network; setting an entrance label in the starting node of each LSP pointing to forwarding information of the LSP; a bearer control entity assigning a transfer path for the service flow and sending the information of all corresponding entrance labels of the transfer path to the ingress edge node of the transfer path; when the service flow needs to be forwarded, the ingress edge node puts the label stack into the data packet of the service flow to generate an MPLS exchange packet; and forwarding the MPLS exchange packet in the bearer network according to the label stack until the packet reaches the egress edge node of the transfer path. The present invention grants high compatibility to the network, minimizes the network investment, and reduces the difficulties in network implementation. | patent |
W1986250082 | Somatotopic dominance in tactile temporal processing | The sense of touch is initiated by stimulation of peripheral mechanoreceptors, and then the spatio-temporal pattern of the receptors' activation is interpreted by central cortical processing. To explore the tactile central processing, we psychophysically studied human judgments of the temporal relationships between two tactile events occurring at different skin locations. We examined four types of two-point temporal judgments-simultaneity, temporal order, apparent motion, and inter-stimulus interval-which differ from one another in time scale and task requirement. To perform any of the four temporal judgment tasks, the brain has to integrate spatially separated inputs. The main focus of the present study is to examine how the spatial separation affects the temporal judgment tasks. Two spatial coordinates can be defined in touch: the somatotopic coordinate, defined by cortical topography, and the spatiotopic coordinate, defined in the environment. In our experiments, the somatotopic distance was manipulated by stimulating the middle and index fingers of the same hand or different hands (ipsilateral vs. bilateral conditions), while the spatiotopic distance was manipulated by increasing the stimulators' separation under bilateral conditions (bilateral-near vs. bilateral-far conditions). Our results clearly demonstrated that all four of the temporal judgments were significantly affected by the somatotopic distance, but only slightly by the spatiotopic distance. The present results, together with the previous findings, suggest that tactile temporal judgments in a wide range of time scale, from several to several 100 ms, primarily reflect processing at the level of somatotopic representation unless the performance is further constrained by spatial processing. | publication |
W2006093207 | Reliability principles, methodology and methods for lifetime design | The aim of integrated lifetime design is to predict and optimise the lifetime quality of the designed facility (building, bridge, tunnel, harbour, road, railway, airport, etc.). Lifetime quality means the capability of a facility or its structures to fulfil the requirements of its users, owners and society over its entire planning and design life (usually 50–100 years). The dictating phase for optimising the lifetime quality of a facility or structure is the planning and design phase, when the degree of freedom is high, and the cost of the phase is low. Generic limit state design aims to fulfil the generic requirements of lifetime quality. At the integrated planning and design stage, performance-based and generic structural limit states design includes the following three classes: (1) Static and dynamic modelling and design against mechanical loads; (2) Durability and service life modelling and design against degrading physical, chemical and biological loads; (3) Usability and service life modelling and design against obsolescence loads. As static and dynamic design are comprehensively dealt with in the literature and in practice, this report focuses on the lifetime safety factor method for durability design and obsolescence design. Main focus of this article is in durability design. On the obsolescence design are presented only a short summary and a number of references, because this design is not much connected to materials research. | publication |
interreg_114 | Building the ADRION Brand Name in Tourism: Indulging all Five Senses PLUS | The ADRION 5 SENSES PLUS Project aims to raise awareness of the ADRION 5 SENSES Project results, to update and fully exploit its outcomes. The ADRION 5 SENSES Project was focused on the ADRION area, studied in-depth the area’s high potential for further development of sustainable tourism, and successfully addressed the common territorial challenge which is the lack of a sustainable tourism model based on innovative, high-quality tourism products and services. In the last couple of years, our reality has changed completely, the Covid-19 pandemic has challenged the tourism model of the ADRION area, raised questions around the health and safety in tourism and has made the whole world rethink travelling and the sustainability of the tourism sector. The ADRION 5 SENSES PLUS comes in a time of need and aims to offer the opportunity to the ADRION 5 SENSES Partnership to revise and update their ADRION 5 SENSES Joint Strategy and Action plan in order to address the new challenges that arise from Covid-19 and to draw a long-term direction regarding sustainable tourism and destination management for the ADRION area which will be adopted by the ADRION 5 SENSES Transnational Network. The ADRION 5 SENSES Transnational Network is committed to continuing the collaboration and work towards creating a sustainable tourism model for the ADRION area and the ADRION 5 SENSES PLUS will further support their work towards the long-term sustainability of the Project results and the creation of a more sustainable and resilient tourism sector. Last but not least, the ADRION 5 SENSES PLUS offers the chance to the Partners and Stakeholders involved to further promote the ADRION 5 SENSES Outputs (i.e., Map of Sensations, Multilingual Web Platform and Exhibition Centres) and to raise awareness of the integrated approach- sensory marketing – which is new and innovative for the ADRION area. The aim of the ADRION 5 SENSES PLUS is to build and promote the ADRION brand name in tourism by indulging all five senses of tourists and by inspiring more stakeholders to join the ADRION 5 SENSES Transnational Network. The vision of the ADRION 5 SENSES PLUS Partnership is to use the available ‘tools’ created by the ADRION 5 SENSES Project, re-start tourism in the ADRION area and enable people to travel, meet, ‘feel’ -get an authentic experience of the area - the ADRION destinations with safety. | project/regional |
AR P060105112 A | SISTEMA DE REGULACION DE LA CARGA O PAR MOTOR PARA MOTOR DUAL, DE COMBUSTION HOMOGENEA DE ENCENDIDO POR COMBUSTION HETEROGENEA | Sistema de regulacion de la carga o par motor para motor DUAL, de combustion homogénea de encendido por combustion heterogénea. El sistema de la presente comprende una válvula de estrangulamiento de la admision, una inyeccion de gasoil para cada régimen de giro y condicion de funcionamiento, y una aportacion de combustible principal para conseguir una realizacion aire/combustible global objetivo predeterminada en el que se regula la carga o par motor a partir de la variacion del flujo de admision que provoca la citada válvula de estrangulamiento de la admision. | patent |
W3023081192 | Abstraction for model checking modular interpreted systems over ATL | We propose an abstraction technique for model checking multi-agent systems given as modular interpreted systems (MIS) which allow for succinct representations of compositional systems. Specifications are given as arbitrary ATL formulae, i. e., we can reason about strategic abilities of groups of agents. Our technique is based on collapsing each agent's local state space with hand-crafted equivalence relations, one per strategic modality. We develop a model checking algorithm and prove its soundness. This makes it possible to perform model checking on abstractions (which are much smaller in size) rather than on the concrete system which is usually too complex, thereby saving space and time. | publication |
989288 | A fully robotic and 3d printing solution for large scale building delivery | 3D Printing for construction sector is booming in the last few years, emerging as an automated manufacturing process that produce complex shape geometries automatically from a 3D computer design model. Although construction 3D Printing has become a revolutionary technology for building, the industry will have to face many challenges related to scalability, work at heights, delivery system, suitability to adverse environment and initial investments. Aware of the limitations of current 3D printing systems for construction, we have developed Evo Constructor, which is a unique mobile system based on a robotic machinery technique that allows to automate all the constructive processes necessary for the execution of buildings and other civil works. The great innovations that differentiates Evo Constructor from any current alternative in the market are its unique cloned axis system, the economic and environmentally friendly characteristics and its self-climbing system, which translates into important cost and time savings. Now, we already have the support of potential customers within the building sector. Nevertheless, we still need to carry out full operational test to validate our solution for its subsequent commercialization. Our market, the 3D Printing Construction Market, was valued at € 0.06bn in 2017, and it is estimated to grow with a CAGR of 78% reaching € 40bn by 2027. Based on our commercialization plan we will offer our solution mainly to construction companies of the building sector, but also architecture studies. It will include the sale and rent of Evo Constructor, but also maintenance and consultancy services. Following our business strategy, we establish an average price of € 0.82M per unit for sale, and € 287k for 6 months rental. Based on the profitability of the project we expect a cumulative revenue of € 22.4M by the third year, meaning a cumulative cash flow of € 13.1M. Considering a total investment of € 1.5M, we expect to get a ROI of 463% by 2022. | project/european |
3733092 | Graph convolutional neural networks for neutrino telescopes | While it is currently undergoing rapid developments, the neutrino sector still has many open questions: the neutrino mass
hierarchy is not known, several parameters of the PMNS matrix are poorly constrained, and the inability to explain the nonzero neutrino masses is a clear indication of physics beyond the Standard Model. Neutrino oscillation experiments at the
IceCube Neutrino Observatory may be able to address these fundamental questions, but the reconstruction of neutrino
interactions in the detector is a challenge which urgently needs to be addressed: the current reconstruction algorithm is
prohibitively time-consuming, cannot account for all known optical anisotropies in the ice, and cannot make full use of all of
the information from new modules in the IceCube Upgrade due to excessive computing time and memory requirements. This
project proposes graph convolutional neural networks (GCN) as a machine learning paradigm excellently suited for neutrino
telescope experiments, with potential to revolutionise reconstruction in IceCube. GCNs impose no structural requirements on
data, requiring only a concept of adjacency, naturally afforded by the spatial, temporal, and causal separation of hits in the
detector. With expected improvements in particle identification of a factor of 10 compared to analytical methods and a factor
10,000 speed-up in reconstruction, GCN-based reconstruction will be developed and implemented in the IceCube-DeepCore
oscillation analysis, to better measure PMNS parameters by improving the atmospheric muon background rejection and
performing per-flavour event categorisation. Powerful and fast GCN-based reconstruction will benefit several physics
analyses in IceCube --- and possibly ANTARES, KM3NeT, and Baikal-GVD --- and help answer the open questions in the
neutrino sector. Finally, the possibility for private and public sector partners to benefit from these high-performance GCN
tools will be explored through intersectional partnerships. | project/european |
US 201815945630 A | TARGETED DRUG DELIVERY AND THERAPEUTIC METHODS USING APO-E MODIFIED LIPID NANOPARTICLES | Methods for targeted delivery of therapeutic agents to a target cell or tissue with lipid nanoparticles comprising ApoE3. In embodiments, the invention specifically relates to targeted delivery of anticancer drugs, antibiotics, antifungal drugs, and diagnostic contrast agents, and associated treatment and diagnostic methods. In embodiments, diseases/conditions treated include those associated with over-expression of LDL receptors. | patent |
W1970523096 | A Link to Improve Stroke Patient Care: A Successful Linkage Between a Statewide Emergency Medical Services Data System and a Stroke Registry | regionalization of stroke care, including diversion to stroke centers, requires that emergency medical services (EMS) systems accurately identify acute stroke patients. A barrier to evaluating and improving EMS stroke patient identification is the inability to link EMS data with hospital data for individual patients. We sought to create and validate a linkage of the North Carolina EMS Data System (NC-EMS-DS) with data contained in the North Carolina Stroke Care Collaborative (NCSCC) Registry.all NCSCC Registry patients arriving to one of three hospitals by EMS in a 6-month period were matched against NC-EMS-DS. Records were deterministically matched on receiving hospital, hospital arrival date/time, age, and sex. We performed linkage validation by providing each site investigator with a stroke patient list derived from North Carolina Stroke Care Collaborative Registry (NC-EMS-DS), matched by individual patient to deidentified data in the NCSCCR. Each site investigator determined the set of true matches by comparing the matched list to a NCSCCR patient identifier key maintained at each site. Incorrect matches were reviewed by the research team to identify methods for future improvement in the matching logic.for the three validation hospitals, 753 NCSCC Registry patients arrived by EMS. For these patients, 473 (63%) matches to local EMS records were identified, and 421 (89%) of the matches were verified using full patient identifiers. Most match verification failures were due to incorrect date/time stamp and inability to find a corresponding EMS record.linking EMS records electronically to a stroke registry is feasible and leads to a large number of valid matches. This small validation is limited by EMS data quality. Matching may improve with better EMS documentation and standardized facility documentation. | publication |
W1721314295 | Co-Teaching: An Educational Promise for Children with Disabilities or a Quick Fix to Meet the Mandates of No Child Left Behind?. | Co-teaching: Cure or Quick-Fix? Is co-teaching a fad or the future for teaching students with disabilities in the regular education setting? The Individuals with Disabilities Act of 1997(IDEA) required that disabled students, to the extent possible, be taught with nondisabled students in the regular classroom. The least restrictive environment standard (LRE) has led to new ideas and models in special education. The co-teaching model is designed to include disabled students in the regular classroom, but in a manner which provides the necessary accommodations to be successful. The standard special education model utilizes the pull-out approach to educating disabled students (Ross-Kidder, 2003). In the elementary school setting the special education teacher pulls the student out of the regular education class for a period of time each day. At the secondary level disabled students would either be self contained or be serviced by a special education teacher for at least one period per day. Districts are now looking at models for pulling-in disabled students (Ross-Kidder, 2003). As more students with learning disabilities (LD) are being included in regular education classrooms, the challenge for school districts is to continue to provide for both the regular education student and the LD students in the same setting. Co-teaching is a collaboration effort between a general education teacher and a special education teacher. Both teachers are responsible for teaching all of the students in the class (Keefe & Moore, 2004). The goals of co-teaching should be to increase instructional options for students, enhance participation of disabled students within the classroom, and to enhance the performance of students with disabilities (Mastropieri, Scruggs, Graetz, Norland, Gardizi, & McDuffie, 2005). There are several approaches to co-teaching, five of which were identified by Friend and Cooke (1995). In the first approach one teacher would be responsible for the teaching while the other circulated throughout the room providing support. The second approach, station teaching, allows the teachers to divide the content and students into groups, splitting time with each group. Parallel teaching, the third approach, allows the class to be divided and each teacher teaches their own group the same content. In the fourth approach, alternative teaching, students are organized into groups, one large and one small, and each teacher instructs one of the groups. The smaller group is recognized as the one requiring the most attention. Co-teaching is a partnership between two teachers, one special education and one regular education. Elementary teachers, in a study conducted by the Keefe and Moore (2004), had a more positive attitude toward co-teaching than did secondary teachers. Elementary teachers were more likely to share a class for at least half a day if not all day, with one or two teachers, while secondary teachers may only be together for one or two periods. The way teachers were paired also made a difference. Teachers generally reported a more positive working arrangement if they chose their co-teaching partner. This also included better communication which in turn led to an enhanced relationship. Teachers who had no choice in selecting their partners, in general, had more negative views of co-teaching. Teachers utilizing the Co-teaching models in the Mastropieri, et al. (2005) study, the Keefe and Moore (2004) study, and the Lawton (1999) study reported problems with having sufficient planning time, primarily in the secondary levels. When special education teachers partnered with more than one teacher, scheduling planning periods to coincide often proved to be difficult, if not impossible. Teachers either had to meet before or after school to plan the curriculum and determine the roles of each teacher. Teachers reported needing a minimum of 45 minutes per day to plan for co-teaching. … | publication |
W2076008530 | Increasing the Wind Turbine Power Using Aerodynamics Shape of the Building | Energy saving techniques including the use of alternative energy sources become more and more popular. One of the alternative energy sources is wind. Wind turbines are highly relevant in the areas of wind (such as coasts). This paper proposes a method of increasing the power of wind turbine due to architectural solutions such as streamlining facade by the example of the school. The calculations of the real increase in wind speed and power of the selected wind turbine have been promoted. The payback period graphs of the unit have been discovered in two variants (with changing the façade and without changing the facade). The economic impact has been analyzed. It has been concluded that the proposed scheme is profitable. | publication |
3739810 | Evolving reversible immunocapture by membrane sensing peptides: towards scalable extracellular vesicles isolation | Extracellular vesicles (EV) are submicron membrane vesicles released by most cells with a fundamental role in cell-to-cell communication. Much interest is flourishing towards their exploitation in regenerative medicine and diagnostics. However, the fulfilment of the EV promise is hampered by severe limitations in their isolation, characterization and manufacturing. A particularly arduous task is to move the isolation of specific EV subpopulations beyond the analytical scale and towards scalable processes. In this scenario, our project will leverage on DNA-directed reversible immunocapturing (rDDI), a new technology developed within FET-OPEN project “INDEX”. rDDI relies on the reversible EV isolation mediated by immunoaffinity followed by intact vesicles recovery upon enzymatic cleavage of a DNA linker used to anchor antibodies on solid supports. Despite unprecedented efficiency in the recovery of highly pure EVs, limitations inherent to antibodies (high costs, batch-to-batch variation and limited versatility of chemical manipulation) substantially impair the scalability of rDDI for any operating scale exceeding the analytical one. MARVEL targets a paradigm shift from antibodies to peptides as an alternative class of affinity ligands for EV capturing by introducing membrane-sensing peptides (MSP) as novel ligands for the size-selective capturing of small EV, unbiased by differential surface protein expression. MARVEL mission is to combine and implement rDDI and MSP technologies, towards the first and best performing ever affinity-based technology for scalable and reversible small EV (<200nm) isolation. The modularity in scaling-up of the novel protocols and kits will be demonstrated on medium/large sample volumes in relevant environments for therapeutic and diagnostics use of EVs and specifically: 1) In the manufacturing of GMP-grade EVs as a medicinal product for cardiac repair; 2) In urine-based liquid biopsy for bladder cancer diagnostics. | project/european |
216106 | Ditas: data-intensive applications improvement by moving data and computation in mixed cloud/fog environments | There is an increasing need to develop data intensive applications able to manage more and more amounts of data coming from distributed and heterogeneous sources effectively, quickly, correctly, and securely. However, the current adoption of Cloud Computing paradigm is not fully appropriate to store and analyse such data: latency, security, and compliance are still significant barriers. At the same time, Fog Computing has emerged as a paradigm promising to fully exploit the potential of the edge of the network involving traditional devices as well as new generation of smart devices, which can process data closer to where they are produced and/or consumed but which cannot ensure the same reliability and scalability as cloud computing offers.
The goal of DITAS is to propose a framework, composed by an SDK and an execution environment, which aims to overcome the barriers that now hamper the adoption of Cloud Computing and increase the adoption of Fog computing by exploiting the full potential of these two paradigms in a synergic way. This will support the development and execution of data-intensive application that are now – and even more in the future – crucial for organizations and companies that want to manage their data in an efficient, reliable, scalable, and secure manner.
Abstractions provided in DITAS with Data Virtualization and Data Utility will expose the data to be managed by the application in terms of Virtual Data Containers which hide the complexity of the underlying infrastructure composed of heterogeneous data sources, smart devices, traditional servers, and sensor networks Distribution could also change dynamically. Conversely, Virtual Data Containers offer to developers the possibility to express requirements on data in terms of performance, quality, security and privacy thus to focus only on the application logic, leaving to the DITAS execution environment the responsibility of finding, processing, and delivering the data according to user needs | project/european |
DE 4402000 A | Düsenanordnung für das Laserstrahlschneiden | A nozzle assembly (34) for laser beam cutting having a truncated conical nozzle body (10) matched to the focussed laser beam with a through drilling (11) for the laser beam, with a nozzle sleeve (13) concentrically surronding the nozzle body (10) and thus forming an annular gap (12), said sleeve having an outlet drilling (14) coaxial with the through drilling (11) for a stream of cutting gas from the annular gap (12) connected to a source of gas, in which the outlet drilling (14) is arranged in front of the through drilling (11) on the workpiece side and has a diameter (D) exceeding that (d) of the through drilling (11). To ensure that thegas stream is deflected from the nozzle parallel to the axis of the laser beam with a minimum of flow losses, the nozzle assembly is designed so that the outlet cross section of the outlet drilling (14) is approximately the same as the transition cross section between the annular gap (12) and the outlet drilling (14). | patent |
US 9910476 W | PLOW IMPROVEMENTS | The present invention provides a powered attachment system for coupling a plow (1, 2) or other implement to a vehicle. A plow lift cylinder (25) extends to push the coupler (64) up into position, aligning the spring loaded pins (64A). Further, the spring loaded pins (64A) automatically engage when the coupler holes are aligned with those of the push beam (62). The single acting, plow blade angle adjust cylinder (17) includes valving in the piston to permit back plowing and a plowed material catcher (11) is provided for V-plows. | patent |
Q4423758 | Apoio ao financiamento do fundo de maneio tendo em conta a deterioração da situação da empresa em resultado da pandemia de COVID-19 | O projeto visa apoiar a manutenção da atividade económica de uma empresa que se tenha encontrado numa situação de escassez súbita devido ao surto da pandemia de COVID-19. O requerente deve solicitar subvenções para financiar o fundo de maneio e para cobrir os custos de funcionamento das atividades durante um período de três meses. | project/regional |
W2886968809 | A generic microgrid controller: Concept, testing, and insights | Abstract Microgrids have garnered attention in recent years as a way to increase the reliability of the grid, increase the reliability of electricity service to customers, adapt to an increasing percentage of intermittent renewable generation, and serve both customer critical loads and the needs of adjacent communities in the case of emergencies such as natural disasters. One barrier to microgrids is the historic cost and lack of standardization associated with microgrid controllers. To reduce this cost and address standardization, specifications for a Generic Microgrid Controller (GMC) were developed with the goal to facilitate the design and ease of adaptation of microgrid controllers to various microgrids of different sizes and with different resources. A GMC must address two core functions, Transition and Dispatch, as well as several optional higher level functions such as economic dispatch, and renewable and load forecasting. The GMC specifications were demonstrated and evaluated using a commercial simulation platform for two different microgrids, a 20 MW-Class community microgrid and a 10 MW-Class medical center microgrid. For each microgrid, the GMC was tested in hardware-in-the-loop (HIL) using an OPAL-RT real-time digital simulator, and the two core functions were assessed. The results established that (1) the GMC is successful in seamlessly transitioning the microgrids to and from an islanded mode, (2) a load/generation mismatch at the time of separation depends on the microgrid configuration and must be lower than a specific value determined by simulation testing, and (3) the GMC Dispatch Function response is acceptable in maintaining, in the islanded mode, 60 Hz for a range of load changes. | publication |
W2415414635 | [The clinical research of aviatic nasal diseases with medical evaluation prevention and control intervention]. | Exploring the clinical features of aviatic nasal diseases to provide references for medical evaluation, prevention and control measures in aircrew.To analysis and summary 605 cases with 503 pilots of nasal diseases in aircrew during 1966 to 2013.(1) There were 605 cases of aviatic nasal diseases, including 550 cases of general diseases and 55 cases of specific diseases. The general nasal diseases included 140 cases of anatomical abnormalities in nasal cavity type, 290 cases of inflammation in nasal cavity, 73 cases of allergy type, 47 cases of cyst and tumor type, and the specific nasal diseases were 55 cases of sinus barotrauma (SB). (2) The, constituent ratio of SB, which was happened in frontal sinus and /or maxillary sinus, was 95.55%. (3) The constituent ratio of cyst and tumor type in nasal cavity was easier causing to SB than anatomical abnormalities, inflammation, allergy disease in nasal cavity (P < 0.05). (4) The grounded constituent ratio of secondary SB was higher than anatomical abnormalities, inflammation, allergy, cyst and tumor disease in nasal cavity (P < 0.05). (5) The ways of hypobaric chamber tests were different for the kinds of aircrew. The qualified adjustment function of sinuses for barometric pressure was an essential condition for aircrew to continue flying. (6) The key point for the treatment of aviatic nasal diseases was to remove pathological change in nasal cavity and sinus and restore sinus ostium patency. The key point for the medical evaluation was to restore normal sinus pressure balance function.The key point of medical evaluation about aviatic nasal diseases is to assess the sinus pressure balance function in hypobaric chamber tests. Normative treatment and medical evaluation can effectively avoid flight accidents and improve the attendance rate for aircrew. | publication |
Q4193034 | COVERBI SRL- CHALLENGE FOR CORPORATE CONSOLIDATION | THE INVESTMENT PLAN DESIGNED BY THE COMPANY MANAGEMENT AIMS TO CONSOLIDATE THE POSITION OF COVERBI IN THE REFERENCE MARKET AND TO COMPLETE THE PRODUCTIVE ASSETS THROUGH THE INSERTION OF NEW MACHINERY THAT WILL BE ABLE TO SIGNIFICANTLY AFFECT THE CUTTING AND SEWING PHASES. THE INTRODUCTION OF NEW AND INNOVATIVE MACHINERY WILL ALLOW THE COMPANY TO UNTIE ITSELF FROM THE MANUAL DYNAMICS OF FABRIC PROCESSING WITH A CONSEQUENT INCREASE IN PRODUCTIVITY, REDUCTION OF TIMING, INCREASE OF THE FINAL QUALITY PERCEIVED, IMPROVEMENT OF THE SAFETY LEVELS OF THE OPERATOR. THE RESULTS THAT THE COMPANY ESTIMATES TO ACHIEVE ARE THE QUALITATIVE IMPROVEMENT OF THE FINAL PRODUCT, CUSTOMER LOYALTY AND THE ACQUISITION OF NEW CUSTOMERS AND CONSOLIDATION IN THE REFERENCE MARKET. | project/regional |
W1519038272 | Content Analysis of Reference Transactions Provides Guidance Regarding Staffing of Library Service Points | A Review of:
 Bishop, B. W., & Bartlett, J. A. (2013). Where do we go from here? Informing academic library staffing through reference transaction analysis. College & Research Libraries, 74(5), 489-500.
 
 Objective – To identify the quantity of location-based and subject-based questions and determine the locations where those questions are asked in order to inform decision-making regarding optimal placing of staff.
 
 Design – Content analysis of location-based and subject-based reference transactions or transcripts collected using LibStats at 15 face-to-face (f2f) service points and via virtual services.
 
 Setting – Virtual and f2f service points at University of Kentucky (UK) campus libraries.
 
 Subjects – 1,852 location-based and subject-based reference transactions gathered via a systematic sample of every 70th transaction out of 129,572 transactions collected. 
 
 Methods – Using LibStats, the researchers collected data on location-based and subject-based questions at all service points at UK Libraries between 2008 and 2011. The researchers eliminated transcripts that did not include complete data or questions with fields left blank. If all question fields were properly completed, identification and coding of location-based or subject-based questions took place. 
 
 Usable transcripts included 1,333 questions that contained sufficient data. For this particular content analysis only the question type, reference mode, and location of question were utilized from the data collected. Unusable transactions were removed prior to content analysis, and reliability testing was conducted to determine interrater and intrarater reliability. Interrater reliability was high (Krippendorff’s alpha = .87%) and intrarater reliability was acceptable (Cohen's kappa = .880). 
 
 Main Results – From the usable transcripts, 83.7% contained location-based questions and 16.3% were subject-based, and a little over 80% of location-based questions and 77.2% of subject-based questions were asked face-to-face (f2f). Of the location-based questions, 11.5% were directional questions and many of these questions were related to finding places inside the libraries. “Attribute of location” questions related to library services and resources, such as finding an item, printing, circulation, desk supplies, and computer problems, made up 72.8% of total question transactions. Researchers found that subject-based questions were difficult to categorize and noted that other methods would be needed to analyze the content of these questions. Professional librarians and library staff are better equipped to answer these questions, and the location where the question asked is irrelevant. The researchers addressed the issue of where questions were asked by recording the reference mode (chat, e-mail, phone, or f2f) and location service point at UK Libraries. Overall, 79% of questions were asked f2f, rather than via chat or e-mail. Researchers think that this is due to a lack of marketing efforts regarding those services, noting that most questions were asked in the system’s large main library, which also receives the most subject-based questions. 
 
 Conclusion – This study can inform the UK Libraries system as to where their resources are most needed and allow for more strategic decision-making regarding staffing. The study could also prompt development of a mobile application to answer location-based questions, though more investigation is needed before moving forward with development of a mobile app. Due to the findings of this study, UK Libraries will deploy their professional library staff to locations where subject-based questions were most frequently asked. Because staffing of libraries is one of the “most expensive and valuable resources,” academic libraries can use this method to validate their current staffing strategies or justify the allocation of staff throughout their systems (p. 499). | publication |
W1589935602 | Global Response of the Ionosphere to Atmospheric Tides Forced from Below: Recent Progress Based on Satellite Measurements | This paper provides an overview on the recent progress in studying the ionospheric response to atmospheric tides forced from below. The global spatial structure and temporal variability of the atmospheric temperature tides and their ionospheric responses are considered on the basis of modern satellite-board data (COSMIC and TIMED). The tidal waves from the two data sets have been extracted by one and the same data analysis method. The similarity between the lower thermospheric temperature tides and their ionospheric responses provides evidence for confirming the new paradigm of atmosphere-ionosphere coupling. This paper provides also new experimental results which give an explanation why the WN4 and partly WN3 longitude structures are so prominent pattern in the ionosphere. These results present evidence indicating that the WN4 (WN3) structure is not generated only by the DE3 (DE2) tide as it has been often assumed. The DE3 (DE2) tide remains the leading contributor, but the SPW4 and SE2 (SPW3, DW4 and SE1) waves have their effects as well in a way that the ionospheric response becomes almost double (1.5 time stronger). The paper presents also the global distribution and temporal variability of the sun-synchronous 24-h (DW1), 12-h (SW2) and 8-h (TW3) electron density oscillations. It has been shown that while the latitude and altitude structure of the ionospheric SW2 response is predominantly shaped by the migrating SW2 tide forced from below the DW1 response is mainly due to daily variability of the photo-ionization. The peculiar vertical structure of the ionospheric TW3 response, that shows downward/upward phase progression, calls for further study of the physical processes shaping this ionospheric response. | publication |
216747 | Industrialization of biobased textile fabrics for clothing applications | FIBFAB project aims to industrialize and launch successfully the production of biodegradable and sustainable polylactic acid (PLA) based fabrics (wool/PLA and cotton/PLA) for the applications in casual (men and womenswear), protective and workwear clothing, and to overcome current limitations of PLA fibres as real alternative to current fabrics (wool and cotton with polyester fibres).
Main FIBFAB project innovations are:
- To obtain a final clothing product 100% bio-based and biodegradable that meets the mechanical and performance requirements of the textile sector
- To improve the current poor thermal resistance of PLA fibres to meet the requirements in several clothing applications by adding additives to enhance the final PLA crystallinity.
- To improve the extrusion process for PLA fibres and especially the mechanical spinning process
-To introduce in the textile market yarns and fabrics produced from PLA fibres combined with cotton or wool. | project/european |
W1985245908 | Gene Expression Profiles in the Fetal Mouse Brain after Etoposide (VP-16) Administration | The aim of this study was to analyze the response of gene expression caused by etoposide (VP-16) in the fetal mouse brain. Four miligrams/kilogram of VP-16 was intraperitoneally injected into pregnant mice on day 12 of gestation (GD 12). Gene expression profiling of the VP-16-treated fetal mouse brain by DNA microarray was performed. The expression changes of the target genes of p53 were also examined by real-time RT-PCR. VP-16 induced S-phase accumulation, G2/M arrest, and eventually apoptosis of neuroepithelial cells in the fetal brain. DNA microarray analysis revealed that 8 of cell cycle control- and apoptosis-related genes were upregulated and that 5 of DNA damage, repair, replication, and transcription genes were also upregulated in the fetal telencephalons at 4 h after VP-16 treatment (HAT). The results of real-time RT-PCR demonstrated that the expression of topoisomerase IIα was increased at 4 and 8 HAT. The expression of pro-apoptotic factors such as puma, noxa, bax, and cyclin G was also increased from 4 to 12 HAT. These results suggest that VP-16 induces DNA damage, DNA repair, cell cycle alternation, and apoptosis in the fetal mouse brain. In addition, VP-16-induced apoptosis is mediated through the mitochondrial pathway in a p53-related manner. The present study will provide a better understanding of the mechanisms of VP-16-induced fetal brain injury. | publication |
W2034667720 | Steady-state mass balance model for mercury in the St. Lawrence River near Cornwall, Ontario, Canada | We have developed a local mass balance model for the St. Lawrence River near Cornwall, Ontario that describes the fate and transport of mercury in three forms, elemental, divalent, and methylated, in a five compartment environment (air, water, sediments, periphyton, and benthos). Our objective was to construct a steady-state mass balance model to determine the dominant sources and sinks of mercury in this environment. We compiled mercury concentrations, fluxes, and transformation rates from previous studies completed in this section of the river to develop the model. The inflow of mercury was the major source to this system, accounting for 0.42 mol month(-1), or 95.5% of all mercury inputs, whereas outflow was 0.28 mol month(-1), or 63.6% of all losses, and sediment deposition was 0.12 mol month(-1), or 27.3% of all losses. Uncertainty estimates were greatest for advective fluxes in surface water, porewater, periphyton, and benthic invertebrates. | publication |
NL 0000563 W | PROTECTION DEVICE FOR THE AIR INLET OF AIRCRAFT TURBINES | The present invention relates to an aircraft engine (2) which on its front is provided with an air inlet through which the air flows into the engine during use, the engine comprising a device (4) for protecting the air inlet, in which engine the device comprises elements (4) which can move between a first, inactive position, in which the air inlet is substantially open, and a second, active position, in which the elements form the protection in front of the inlet opening. Furthermore, it is possible for the elements to be attached at one end to a positioning device which can move the elements between the active and inactive positions. | patent |
US 56601595 A | Method and apparatus for adjusting video data to limit the effects of automatic focusing control on motion estimation video coders | A method, and computer program are provided for adjusting motion estimation video data to remove unwanted data generated by an automatic focusing control (AFC) circuit on the video data recorder. One or more edges or fine points in a sequence of motion compensated images is identified. Difference frames composed of pixel differences are generated from the motion compensated images. The difference frames are examined for evidence of AFC action. In the event AFC action is identified, one or more frames of the sequence of difference frames are filtered to remove the AFC effects. The filtered difference frames are encoded. Identification can be made by detecting a component of oscillation in a comparison of summed pixel differences of a sequence of frames. The difference frames may be filtered by reducing the energy level of one or more of the difference frames or by discarding one or more of the difference frames. | patent |
175357 | Investigation of the interaction of mesenchymal stem cells with aptamer modified surfaces using light-addressable potentiometric sensors (laps) | The aim of this project is to develop a new method to immobilize aptamers of stem cells onto silicon-on-sapphire substrates, to capture cells by affinity interaction between aptamer and target cells, and investigate two-dimensional electrochemical images of parameters such as local cell impedance, cell surface charge, ion channel activity, and two-photon fluorescence images with subcellular resolution using the impedance imaging technique Scanning Photo-induced Impedance Microscopy and the electrical potential imaging technique Light-Addressable Potentiometric Sensors. Aptamers are artificial functional oligonucleic acids which can bind their targets with high affinity and specificity. Aptamers with specificity to target integrin heterodimers will be developed and patterned on LAPS substrates and the mechanism of attachment regulated stem cell differentiation studied. The proposed technique has the advantage that functional electrochemical imaging of the cell-surface interface can be carried out, which is not accessible to other electrochemical techniques.
The results of the project will inform the development of tissue engineering materials and impact on the health care and biomaterials industries, which are central to Europe's ongoing and future economic success, and are directly relevant to the theme priority of personalizing health and care in Horizon 2020.
The applicant is an outstanding young scientist who recently finished his PhD at Peking University and has already authored and co-authored 14 papers, worked on different multidisciplinary projects in China and Japan, and brings a lot of relevant experience to the project in the areas of aptamers, electrochemistry, and biosensors. During the fellowship, he would develop competencies in electrochemical imaging, semiconductor processing and single cell analysis, expand his research network and gain skills such as project management and grant writing allowing him to develop an independent research career. | project/european |
interreg_781 | Cross the Gap - Accessibility for social and cultural inclusion | Cross the gap project’s main goal is to create new models of intervention to sustain social inclusion of people with disabilities in Italy and Greece, by combining physical accessibility and broader fruition of cultural activities.
On the one hand, the project wants to ensure full accessibility to cultural and historic sites, through concrete infrastructural works, aimed at demolishing any barrier to the free movement of visitors.
On the other hand, the project will favour the active social inclusion of people with disabilities, by facilitating the overtaking of mental barriers that obstructs the involvement of people with special needs in cultural life at local and international level.
Theatre laboratories involving people with disabilities will be organized at cross-border level, and internationally renowned theatre companies working with people with special needs will be invited to perform their shows in Italy in order to raise awareness on the fruitful involvement of the project target beneficiaries in cultural and social life. | project/regional |
1263858 | Late antiquity after antiquity: the last of the ancient platonists in the early modern period | LAAA will provide the first systematic study of the rich – yet understudied – interpretative legacy of late antiquity in the history of Western philosophy, with a focus on Platonism. It will show that in the early modern period the most influential portraits of the ancient philosophical past were inspired and shaped by representations of this past produced in late antiquity.
In its attempt to explore the philosophical heritage of these representations, LAAA will begin in the investigation of the hermeneutical approach of the humanist philosopher Marsilio Ficino (1433-1499), who produced the first Latin translation of the entire Platonic corpus by using the newly discovered texts of the late antique Platonists as interpretative tools.
This approach created a form of Platonism deeply imbued with the theurgically oriented tradition of late antiquity. LAAA’s goals are to disentangle the different interpretative threads which run under the label ‘early modern Platonism’ and to examine its impact in different fields of early modern European knowledge, as well as its role in the shaping of our intellectual and cultural identity. By retracing the complex narrative of filiation which characterizes the reception history of Platonism, LAAA will reassess the role of late antiquity not in its own time, but from the general viewpoint of the historical development of Western thought. This is a totally new perspective in the study of late antiquity, which will be examined as a dynamic territory for the preservation, transformation and transmission of classical texts, as well as a longstanding source of authority and inspiration. | project/european |
W2030509534 | Effect of land use and land cover change on ecosystem services in Naidong County on the Tibetan Plateau, China | Land use and land cover change (LUCC) on a regional scale is one of the major research topics in global climate change studies. In recent years, an increasing number of researchers have highlighted the significance of case studies in understanding LUCC patterns and processes. The Tibetan Plateau ecosystem is a typical fragile ecosystem that is extremely difficult to restore once it is damaged. Thus, studies on LUCC and its effects on the environment have great theoretical and practical significance. In this study, LUCC and changes in ecosystem services in Naidong County on the Tibetan Plateau, China between 1988 and 2000 are investigated. LANDSAT Thematic Mapper (TM) of 1998 and Enhanced Thematic Mapper Plus (ETM+) images of 2000 are used to detect LUCC, and then changes in the values of ecosystem services delivered by each land category are investigated. Finally, the contribution of various ecosystem functions to the overall value of ecosystem services is discussed. The results show that the enhancement of forest areas is the most prominent characteristic of change in land use, specifically the conversion from 659.23 ha of wetlands, 501.51 ha of grasslands, and 163.07 ha of desert to forests from 1988 to 2000 in study area. The total value of ecosystem services in Naidong County declined from ¥1655.16 million to ¥1640.21 million between 1988 and 2000. This decrease can be largely attributed to the loss of wetlands (valued at ¥36.58 million), whereas the ecosystem services value of forests increased by ¥25.60 million during that period. The sensitivity analysis revealed that the contributions of gas regulation, soil formation and erosion control, biological diversity, and raw materials to the total value of ecosystem services increased over the 12-year period. Moreover, the contributions of waste treatment, water conservation, climate regulation, recreation and culture, and food production significantly decreased during the same period. | publication |
W3214326772 | Viabilidade financeira das regiões metropolitanas: contribuição ao debate e aportes do caso de Belo Horizonte | Este artigo analisa as regiões metropolitanas (RMs) brasileiras sob o viés do financiamento das funções públicas de interesse comum, decorrentes do planejamento urbano em escala regional. Apresentase breve histórico das formas de constituição das RMs e das diferentes abordagens para a gestão metropolitana desde a década de 1960 até a promulgação do Estatuto da Metrópole. Analisam-se as principais fontes de recursos para custeio da gestão metropolitana, as dificuldades de captação, os desequilíbrios da repartição orçamentária interfederativa, bem como os conflitos políticos que prejudicam a implementação de arranjos cooperativos. Para ilustrar a pesquisa, apresentam-se a evolução e o desenvolvimento da RM de Belo Horizonte, que se tornou referência de governança interfederativa pelo processo democrático de construção de seu Plano de Desenvolvimento (2011) e pela inovação dos arranjos técnico-políticos de gestão. | publication |
W2613192364 | Turbulence intensity measurement in the wind tunnel used for airfoil flutter investigation | The paper reports on hot wire turbulence intensity measurements performed in the entry of a suction-type wind tunnel, used for investigation of flow-induced vibration of airfoils and slender structures. The airfoil is elastically supported with two degrees of freedom (pitch and plunge) in the test section of the wind tunnel with lateral optical access for interferometric measurements, and free to oscillate. The turbulence intensity was measured for velocities up to M = 0.3 i) with the airfoil blocked, ii) with the airfoil self-oscillating. Measurements were performed for a free inlet and further with two different turbulence grids generating increased turbulence intensity levels. For the free inlet and static airfoil, the turbulence intensity lies below 0.4%. The turbulence grids G1 and G2 increase the turbulence level up to 1.8% and 2.6%, respectively. When the airfoil is free to oscillate due to fluid-structure interaction, its motion disturbs the surrounding flow field and increases the measured turbulence intensity levels up to 5%. | publication |
W2011529207 | Catalytic gasification of automotive shredder residues with hydrogen generation | Abstract Hydrogen is a clean and new energy carrier to generate power through the Proton exchange membrane fuel cell (PEMFC) system. Hydrogen can be effectively turned out through the catalytic gasification of organic material such as automotive shredder residues (ASR). The main objective of this manuscript is to present an analysis of the catalytic gasification of ASR for the generation of high-purity hydrogen in a lab-scale fixed-bed downdraft gasifier using 15 wt.% NiO/Al2O3 catalysts at 760–900 K. In the catalytic gasification process, reduction of Ni(II) catalyst into Ni(0) has been confirmed through XANES spectra and consequently EXAFS data shows that the central Ni atoms have Ni–O and Ni–Ni bonds with bond distances of 2.03 ± 0.05 and 2.46 ± 0.05 A, respectively. ASR is partially oxidized and ultimately converts into hydrogen rich syngas (CO and H2) and increases of the reaction temperature are favored the generation of hydrogen with decomposition of the CO. As well, approximately 220 kg h−1 of ASR would be catalytically gasified at 760–900 K and 46.2 atm with the reactor volume 0.27 m3 to obtain approximately 3.42 × 105 kcal h−1 of thermal energy during over 87% syngas generation with the generation of 100 kW electric powers. | publication |
W2140569025 | Calculation of porosity from nuclear magnetic resonance and conventional logs in gas-bearing reservoirs | The porosity may be overestimated or underestimated when calculated from conventional logs and also underestimated when derived from nuclear magnetic resonance (NMR) logs due to the effect of the lower hydrogen index of natural gas in gas-bearing sandstones. Proceeding from the basic principle of NMR log and the results obtained from a physical rock volume model constructed on the basis of interval transit time logs, a technique of calculating porosity by combining the NMR log with the conventional interval transit time log is proposed. For wells with the NMR log acquired from the MRIL-C tool, this technique is reliable for evaluating the effect of natural gas and obtaining accurate porosity in any borehole. In wells with NMR log acquired from the CMR-Plus tool and with collapsed borehole, the NMR porosity should be first corrected by using the deep lateral resistivity log. Two field examples of tight gas sandstones in the Xujiahe Formation, central Sichuan basin, Southwest China, illustrate that the porosity calculated by using this technique matches the core analyzed results very well. Another field example of conventional gas-bearing reservoir in the Ziniquanzi Formation, southern Junggar basin, Northwest China, verifies that this technique is usable not only in tight gas sandstones, but also in any gas-bearing reservoirs. | publication |
W1985524967 | Detailed Design of a 2,000 A, 400 mH Toroid-Type HTS DC Reactor for an HVDC System | General DC reactors in high-voltage direct current systems experience an electrical loss due to the resistance from copper winding in the DC reactor. The toroid-type high-temperature superconducting (HTS) DC reactor can be expected to decrease the disadvantages associated with general DC reactors. In this paper, the design of a toroid-type HTS DC reactor is presented. The magnetic fields of the toroid-type HTS DC reactor magnet were analyzed using the finite element method program. The conduction cooling system of the HTS DC reactor was designed based on the results of thermal analysis. The target current and inductance of the HTS DC reactor were 2,000 A and 400 mH, respectively at 20 K. | publication |
W1591662923 | Welfare Facilities for better Industrial Relations – An empirical study of Indian Jute Industry in Post Liberalisation | Provision of welfare amenities enables the workers to live a richer and more quality life and thereby contributes to their efficiency and productivity. It helps to maintain industrial peace. Increased productivity of an industrial undertaking, indisputably, results from mental happiness of employees.Mental happiness of an employee in turn is a function of welfare facilities provided by the employer. Welfare facilities make the life of the employee comfortable and happy. The labour welfare covers a broad field and connotes a state of well-being, happiness, satisfaction, conservation and development of human resources. The Jute Industry, which is one of the oldest traditional industry providing employment opportunities to huge number of population particularly unskilled and semiskilled. Earlier studies revealed that there were lot of strikes and lockouts taken place in Jute Industry. This is one of the traditional industries which lost huge number of manly hours, loss of productivity due to poor industrial relations. So, the researcher studied the impact of liberalization on industrial relations in Jute Industry in post liberalization particularly relating to implementation of Welfare facilities in North Coastal Andhra Pradesh. The author collected the opinions from the sample respondents through a structured questionnaire and analyzed the same with the help of five point Likert scale and weighted average method. It reveals that in post liberalization employers implement the statutory and some of the non-statutory facilities like restrooms, lunchrooms, hygienic canteen facility, first-aid boxes, ambulance facility, etc. which lead to the more employee welfare. | publication |
W1750693315 | Camera-Vision Based Oil Content Prediction for Oil Palm (Elaeis Guineensis Jacq) Fresh Fruits Bunch at Various Recording Distances | In this study, the correlation between oil palm fresh fruits bunch (FFB) appearance and its oil content (OC) was explored. FFB samples were recorded from various distance (2, 7, and 10 m) with different lighting spectrums and configurations (Ultraviolet: 280-380nm, Visible: 400-700nm, and Infrared: 720-1100nm) and intensities (600watt and 1000watt lamps) to explore the correlations. The recorded FFB images were segmented and its color features were subsequently extracted to be used as input variables for modeling the OC of the FFB. In this study, four developed models were selected to perform oil content prediction (OCP) for intact FFBs. These models were selected based on their validity and accuracy upon performing the OCP. Models were developed using Multi-Linear-Perceptron-Artificial-Neural-Network (MLP-ANN) methods, employing 10 hidden layers and 15 images features as input variables. Statistical engineering software was used to create the models. Although the number of FFB samples in this study was limited, four models were successfully developed to predict intact FFB’s OC, based on its images’ color features. Three OCP models developed for image recording from 10 m under UV, Vis2, and IR2 lighting configurations. Another model was successfully developed for short range imaging (2m) under IR2 light. The coefficient of correlation for each model when validated was 0.816, 0.902, 0.919, and 0.886, respectively. For bias and error, these selected models obtained root-mean-square error (RMSE) of 1.803, 0.753, 0.607, and 1.104, respectively. | publication |
CA 2541884 A | NON-WHITE CONSTRUCTION SURFACE | A non-white construction surface comprising a substrate, a first reflective coating on at least a portion of an outer surface of the substrate, the coated substrate exhibiting a minimum direct solar reflectance value of at least about 25 %, and a second reflective coating on at least a portion of the first reflective coating, wherein the combination of the first reflective coating and the second reflective coating provide the substrate with at least one of (i) a reflectivity of at least about 20 % at substantially all points in the wavelength range between 770 and 2500 nm, and (ii) a summed reflectance value of at least 7000 as measured in the range between 770 and 2500 nm inclusive. Also provided are various substrates having the coatings described as well as methods of providing the described construction surfaces. | patent |
219477 | Could senescence be adaptive? causes and consequences of aging across the tree of life | Why do organisms age? This is surely one of the most compelling questions in biology. With advancing age, organisms can see physiological decline leading to higher mortality and lower fertility, a process known as ‘senescence’. The foundations of aging research state senescence should be inevitable in any organism, and is likely a by-product of attenuation in force of selection with age. But is senescence inevitable? Could senescence be adaptive?
Senescence is not inevitable, according to recent research from the Max Planck Odense Center, University of Southern Denmark. Species’ aging trajectories are diverse; mortality and fertility may increase, decrease or stay constant with age. We need a new way to understand aging, which recognises this diversity and seeks to understand pattern and process in the evolution of aging across the tree of life. The WHYAGE project explores ecological consequences and evolutionary causes of diversity in aging from this ‘macro’ perspective.
Senescence could be adaptive. This proposal presents a theoretical framework under which certain environmental disturbances affecting population age structures could, through population-level processes, favour senescent individuals. More generally, diverse environmental disturbance regimes could help explain diversity of aging across the tree of life.
Three objectives facilitate the project. First, demographic method development will allow better understanding of aging trajectories in mortality and fecundity, and population dynamics influenced by these. Second, comparative phylogenetic analyses of global demographic databases of plants and animals will uncover the consequences of aging for population dynamics across the tree of life. This knowledge will inform the third objective; development of theoretical population models exploring how environmental disturbances and population dynamics feed into evolutionary processes, and using these to find conditions under which senescence may be adaptive. | project/european |
3729557 | Multi-Camera autonomous robotic set for the ultimate and cost-effective live video | Inconsistent quality, high personnel costs and personnel admin overheads are the main bottlenecks faced by video production companies. Small-medium ones besides, must handle with very tight budgets, offering the bare minimum as result (limited camera angles and repetitive movements) and risking zero profits in case of production overruns. Automation (artificial intelligence and robotics that replace repetitive and routine tasks) has emerged as an innovative solution to execute production tasks more efficiently and allow companies to remove economic bottlenecks and devote more resources to creative activities. However state-of-the-art automation technologies are limited to assistive systems or partial automation based on pre-established scripts (cameras' movement, framing time and broadcast sequence), so they are not suitable for live shows such as sports events or concerts.
Seervision, the only player offering an affordable full automation solution, will revolutionize the video production industry through Multi RoboDoP: an easy-to-use platform that autonomously controls multiple cameras, tracks objects smoothly and takes smart decisions to perform all operational tasks of traditional crews at a superior quality. Multi RoboDoP will disrupt the cost structure of today’s video productions by halving their production costs. Moreover, we will unlock 50% of the market that cannot afford professional video productions (mid-sized video production companies and small studios) while we increase ROI for large-scale companies.
So far, we have invested more than €1M to reach TRL7 and we envisage €2.19M and 1.5 years to finish developing our proprietary multi-camera coordination software, prepare its scale-up and its market launch.
We have identified 12 priority target countries representing a SAM of >€700M. After launch to market in Q4 2021, we estimate 2.5 years to reach break-even, 4 years to get a 3-4% overall market share, €27.8M in revenues and a ROI of 6.67. | project/european |
W2951680 | The Penumbra Coil 400 System for Treatment of Wide-Necked Intracranial Aneurysms: Initial Single-Center Experience | Endovascular treatment of wide-necked intracranial aneurysms frequently requires stent- or balloon-assisted coiling to prevent coil herniation into the parent artery. Provided that coils can be securely deployed within the aneurysm sac, these adjunctive devices and their associated risk can be avoided. The Penumbra 400 Coil (PC-400) has a larger diameter than conventional coils and is constructed completely of metal, a feature that increases the coil stability and may improve its ability to respect the aneurysm neck. The purpose of this study was to examine the frequency of adjunctive stent usage when coiling wide-necked intracranial aneurysms with the PC-400 in comparison with conventional coils. We examined consecutive patients with unruptured wide-necked aneurysms treated at our institution with endovascular coils. Aneurysm characteristics and procedural outcomes were compared between patients treated with PC-400 compared with a control group treated with conventional coils. Thirty-eight patients met criteria for this study. Stent-assisted coiling was required in 34 % fewer cases using PC-400 compared with conventional coils (P = .049). Fewer coils and less length were required with the PC-400 to obtain the same packing densities, occlusion types, and short-term stability. This may reduce treatment cost and prove to be valuable in patients with contraindications to dual antiplatelet therapy.KeywordsIntracranial aneurysmEmbolizationPenumbra Coil 400Stent-assisted coilingWide necked | publication |
W2382876515 | Research on Smoke Control by Combination of Corridor Smoke Outlet and Smoke Retaining Screen in High-rise Buildings | The corridor of high-rise building is the important approach to dissipate smoke in the fire,and also the only way for personnel evacuation.In this paper,through establishing the mathematical model of smoke movement in the high-rise building,the k-e equation 3-D turbulent model were adopted,and FLUENT software was utilized to simulate the mechanical smoke discharge in different smoke discharge modes in the fire of high-rise buildings,the distance between different smoke outlets in the straight corridor and smoke retaining screen was compared and analyzed,as well as the smoke dissipation conditions in the corridor with the smoke retaining screen in different heights.The results illustrated that the smoke retaining screen set in the straight corridor could well reduce the hazard of the downstream corridor of the smoke retaining screen.Furthermore,the distance between the smoke retaining screen and smoke outlet had small influence on the smoke discharge,and the drooping height of the smoke retaining screen was the key factor to affect the smoke discharge effect.In addition,whenever the drooping height of the ceiling screen was increased by 0.2 m,the average downstream temperature would be reduced by 10 ℃. | publication |
W2029080394 | Synthetic Mimics of Antimicrobial Peptides from Triaryl Scaffolds | In this report, we describe the synthesis of a new series of small amphiphilic aromatic compounds that mimic the essential properties of cationic antimicrobial peptides using Suzuki-Miyaura coupling. The new design allowed the easy tuning of the conformational restriction, controlled by introduction of intramolecular hydrogen bonds, and the overall hydrophobicity by modifications to the central ring and the side chains. This approach allowed us to better understand the influence of these features on the antimicrobial activity and selectivity. We found that the overall hydrophobicity had a more significant impact on antimicrobial and hemolytic activity than the conformational stiffness. A novel compound was discovered which has MICs of 0.78 μg/mL against S. Aureus and 6.25 μg/mL against E. Coli, similar to the well-known antimicrobial peptide, MSI-78. | publication |
W2564715175 | Turning Left: Counter-Hegemonic Exhibition-Making in the Post-Socialist Era (1989-2014) | This research examines how the practice of curating has been used to further counter-hegemonic agendas in public art institutions since 1989. The central aim is to provide a fuller, contextualised, and medium specific understanding of the how the institutional exhibition might be used to challenge the hegemony of neoliberalism and the post-political consensus politics that sustains its dominance. It provides insights, through both historic case studies and reflective practice, that problematise the idea that the institutional art exhibition is a viable medium for counter-hegemonic critique, or represents the ideal space for the development of an agonistic public discourse.This thesis presents collaborative research undertaken with Tate Liverpool and Liverpool John Moores University. The research presented both extrapolated from, and contributed to, the development of an exhibition, co-curated with Tate Liverpool, entitled Art Turning Left (8 November 2013 – 2 February 2014) and a supplementary publication of the same name. The first section investigates how the idea that curators can counter neoliberal dominance, through institutional exhibition-making, developed. It draws from analyses of previous exhibitions, and the theory of Chantal Mouffe, in order to critically evaluate the curatorial application of counter-hegemonic critique and agonistic practice. It also provides a review of how exhibitions (held in major art institutions since 1989) have articulated politics, in order to determine their relationship to neoliberal dominance, and to identify significant gaps in the dialogue facilitated by these institutions. These analyses provides the theoretical and contextual grounding for the final two chapters, which provide a rationale and critical evaluation of my own attempt to develop an alternative counter-hegemonic curatorial strategy for the exhibition at Tate Liverpool. They document, and analyse, the areas of dissensus, and the ideological and pragmatic limitations that emerged, in trying to realise these theoretical propositions (in practice) in a public art museum. The thesis therefore provides a critical framework for the development of an alternative practice that positions the exhibition as a form of post-political critique and specifically targets the hegemonic role that institutional exhibitions play in reinforcing class distinctions and devaluing nonprofessional creativity. | publication |
W30523602 | Interference Test and Pulse Test | The purpose, development history, test design method, data acquisition and interpretation methods, and typical field examples of their application of the interference test between wells or layers and pulse test are introduced in this chapter. Because the interference test can be used to solve many problems about the connectivity between wells or layers and to obtain parameters about the connectivity between wells and the size of the connected area in the reservoir, they are very effective methods in dynamic study. However, there are some special difficulties and special requirements in data acquisition and operation in the field that cause the success rate of the data acquisition of these tests to be low. The author makes some suggestions on effective design and operation procedures for a successful interference test on the bases of his own experience accumulated in the field after many years. Some typical field practice examples are given in this chapter, for example, study results of interference tests between wells in the JB gas field made clear the connectivity of thin zones with low permeability in an area 2 km long in the Ordovician formation, but the heterogeneity there is quite serious; the study of interference tests between wells in the SLG gas field probed into the characteristics of lithological boundaries of the fluvial facies deposited in sandstone in the Permian system formation; and the study of interference tests in the SL gas field provided some results, such as conforming the sealing of some faults and anisotropy of the permeability. | publication |
W4289530697 | L’effet de la réforme des retraites de 2010 sur l’absence maladie | En 2010, la France a réformé son système de retraite en augmentant de 2 ans l’âge d’ouverture des droits avec une période de transition relativement courte, ne s’étendant qu’entre les générations 1950 et 1955. Si l’objectif affiché est bien l’augmentation de l’offre de travail des seniors et la réduction du déficit des caisses de l’assurance retraite, plusieurs études montrent que ce type de réforme engendre aussi des effets induits en termes de recours à des régimes alternatifs tels que le chômage ou l’invalidité. Dans cet article, nous mobilisons la base administrative Hygie 2005-2015 pour explorer un autre de ces effets indirects : celui sur les absences maladie. Si un tel effet s’avérait important, cela impliquerait que le gain de réduction du déficit des caisses d’assurance retraite, s’accompagne d’un surcoût pour l’assurance maladie, lié à l’augmentation des indemnités journalières à payer. Nous considérons alternativement diverses mesures de l’absence maladie et montrons que la réforme des retraites a bel et bien entraîné une augmentation de la probabilité d’avoir au moins un arrêt maladie (+1,7 point de pourcentage) et du nombre annuel de jours d’arrêts maladie (+1 jour) et ce, pour l’ensemble de la population, mais avec des effets différenciés selon le genre : plus prononcés pour les femmes s’agissant de la probabilité d’arrêt et du nombre d’arrêts, ils le sont moins s’agissant de la durée de ces arrêts (+0,7 jour pour les femmes et +1,3 jour pour les hommes). | publication |
W2088630428 | Seasonal, Diurnal and Spatial Variations of Environmental Variables in Australian Livestock Buildings | To identify the most practical and representative sampling locations for air quality and environmental variables inside intensive piggery buildings, the variation in the spatial, diurnal and seasonal concentration of major airborne pollutants, and related environmental parameters, were analysed over a 2.5-day period at several locations within different piggery buildings. Major airborne pollutants including, ammonia, carbon dioxide, and airborne particles were monitored along with environmental parameters of airspeed, temperature and humidity. To determine the air quality within each building, cyclone attachments were installed to measure particles of less than 5 .m along with a seven hole sampler attachment to measure inhalable airborne particles. An Osiris optical particle counter also monitored the concentrations of airborne particles. Ammonia and carbon dioxide were monitored using a multi-gas monitoring machine and airspeed was measured using a hot-wired anemometer. Interesting patterns in the concentration of carbon dioxide, dust and ammonia were observed over time and space. Carbon dioxide, airspeed and dust concentration demonstrated an obvious circadian pattern. The difference in the concentrations of ammonia and carbon dioxide was not statistically significant at alternative sampling locations inside each building. However, the gravimetric measurements indicated that the concentrations of inhalable particles were not uniform throughout the buildings and proved to be higher above the walkways. Ammonia and respirable particle concentrations were significantly higher in summer when compared to winter conditions. These results combined, identifi ed the most appropriate sampling times and sampling places for reliable evaluation of air quality in intensive livestock buildings. | publication |
W4320003762 | Un singular ambiente doméstico del Hierro I en el interior de la península ibérica: la casa 1 del Cerro de San Vicente (Salamanca, España) | Se presentan los resultados de las excavaciones (2006, 2017 y 2021) en un sector de la aldea del Hierro I del Cerro de San Vicente (Salamanca). Se ha exhumado un agregado informal de edificios y estructuras adjetivas de adobe cuyo patrón espacial es afín al esquema transcultural patrilocal. El artículo se centra en la casa 1 y sus cenizales. Tal vivienda fue excepcional por su larga e ininterrumpida biografía, su mobiliario de barro –con dos poyos que pudieron acoger hasta 20 personas y un hogar con forma de piel de toro extendida– y su abandono ritualizado –quemada c. 650-575 a.C. y recrecida con adobes de sus paredes–. La excavación reveló una alta concentración de molinos y vajilla fina local pintada, así como instrumental de labores especializadas y altamente cualificadas –alfarería e hilado–. Sobresale un lote de hallazgos inéditos en el interior de la península ibérica: exóticos abalorios y vajilla de fayenza del Mediterráneo oriental, cerámica de engobe rojo fenicia y objetos litúrgicos y coroplástica con paralelos tartésicos y mediterráneos. Todos estos hallazgos indican que la casa 1 acogió una asidua actividad social –banquetes y transacciones con huéspedes– como cabaña de reuniones de un grupo corporativo extenso, donde acabaron tan destacados objetos. | publication |
Q4764766 | ANCIENT PHARMACY OF MAGDALENE BY DOTT. Torelli ROBERTO & C. S.N.C. | THE PHARMACY OF MADDALENA IS LOCATED IN GENOA, IN THE DISTRICT OF MADDALENA THAT HAS ABOUT 20,000 PEOPLE BETWEEN RESIDENTS AND OFFICES (MUNICIPALITY, CHAMBER OF COMMERCE, BANKS) AND IN WHICH IT OPERATES SINCE 1700; IT IS IN FACT “HISTORICAL WORKSHOP”, IDENTIFIED IN THE REGISTER UNDER NUMBER 005. THE ACTIVITY CARRIED OUT IS THAT OF THE PHARMACEUTICAL SERVICE TO THE POPULATION. THE CATCHMENT AREA IS MAINLY MADE UP OF RESIDENTS, ELDERLY PEOPLE, YOUNG COUPLES, BUT ALSO TOURISTS AND CRUISERS AS THE PHARMACY IS LOCATED IN THE TOURIST ROUTE OF THE HISTORIC GENOESE CENTER, LOCATED AS IT IS IN FRONT OF THE CHURCH OF MADDALENA, PARISH OF CASTELLETTO AND JEWEL — JUST RESTORED — OF THE BAROQUE AND ROCOCO GENOESE. THE PHARMACY CONSTITUTES FIRST LEVEL MEDICAL CARE IN THE AREA: DISPENSE PRESCRIPTION MEDICINES, SELF-MEDICATION DRUGS AND SERVICES SUCH AS BLOOD ANALYSIS, PRESSURE MEASUREMENT, FAT MASS, PLETTOMETRIA, OFFERS CUP RESERVATIONS SERVICE IN AGREEMENT WITH REGI | project/regional |
220264 | The first bantu speakers south of the rainforest: a cross-disciplinary approach to human migration, language spread, climate change and early farming in late holocene central africa | The Bantu Expansion is not only the main linguistic, cultural and demographic process in Late Holocene Africa. It is also one of the most controversial issues in African History that still has political repercussions today. It has sparked debate across the disciplines and far beyond Africanist circles in an attempt to understand how the young Bantu language family (ca. 5000 years) could spread over large parts of Central, Eastern and Southern Africa. This massive dispersal is commonly seen as the result of a single migratory macro-event driven by agriculture, but many questions about the movement and subsistence of ancestral Bantu speakers are still open. They can only be answered through real interdisciplinary collaboration. This project will unite researchers with outstanding expertise in African archaeology, archaeobotany and historical linguistics to form a unique cross-disciplinary team that will shed new light on the first Bantu-speaking village communities south of the rainforest. Fieldwork is planned in parts of the Democratic Republic of Congo, the Republic of Congo and Angola that are terra incognita for archaeologists to determine the timing, location and archaeological signature of the earliest villagers and to establish how they interacted with autochthonous hunter-gatherers. Special attention will be paid to archaeobotanical and palaeoenvironmental data to get an idea of their subsistence, diet and habitat. Historical linguistics will be pushed beyond the boundaries of vocabulary-based phylogenetics and open new pathways in lexical reconstruction, especially regarding subsistence and land use of early Bantu speakers. Through interuniversity collaboration archaeozoological, palaeoenvironmental and genetic data and phylogenetic modelling will be brought into the cross-disciplinary approach to acquire a new holistic view on the interconnections between human migration, language spread, climate change and early farming in Late Holocene Central Africa. | project/european |
W1568412157 | Two new species of Lepidosperma (Cyperaceae) occurring in the Perth area of Western Australia | Barrett, R.L. & Wilson, K.L. Two new species of Lepidosperma (Cyperaceae) occurring in the Perth area of Western Australia. Nuytsia 23: 173–187 (2013). Lepidosperma apricola R.L.Barrett is a new species from the Darling Range in Western Australia. An isolated population also occurs in Kings Park, in the heart of Perth. This species has been confused with L. leptostachyum Nees. in the past. Lepidosperma calcicola R.L.Barrett & K.L.Wilson is a new species from coastal dune systems on the west coast of Western Australia, which has been previously confused with a number of other taxa. It has been listed on FloraBase as Lepidosperma common species occurring in the Perth region of Western Australia (and more broadly in the South West Botanical Province) that have been unnamed up until now. | publication |
W2347017957 | New and little-known bryozoans from Monte León Formation (early Miocene, Argentina) and their paleobiogeographic relationships | Abstract The bryozoan fauna from the South American Cenozoic is poorly known. The study of new material collected in the Monte León Formation (early Miocene), gave us the opportunity to describe four new species: Valdemunitella canui n. sp., Foveolaria praecursor n. sp., Neothoa reptans n. sp., and Calyptotheca santacruzana n. sp. Two of them ( V . canui and C . santacruzana ) were first recorded by F. Canu and interpreted as recent species from the Australian bryozoan fauna, but are herein described as new species. The stratigraphic range of Otionella parvula (Canu, 1904) is extended to the early Miocene. The present study emphasizes the close relationships between the South American Neogene bryozoan faunas and those of other Gondwanan sub-continents such as New Zealand and Australia. | publication |
W2057001965 | Modulation instability in the sub-cycle regime | Summary form only given. Modulation instability (MI) in Xe-filled kagomé-style hollow core photonic crystal fibre (PCF) has recently been demonstrated experimentally using 500 fs laser pulses centred at λ = 800 nm with energies of a few μJ [1]. It is known that MI leads to the formation of fundamental solitons [2] with average amplitude and temporal width given by [3]: τ<;sub>0<;/sub> = √2T<;sub>0<;/sub>(ΠN), where T<;sub>0<;/sub> is the duration of the input pulse, N = √(γP<;sub>0<;/sub>T<;sub>0<;/sub>/|β2|) the soliton order, γ the nonlinear coefficient, P0 the pump peak power and β<;sub>2<;/sub> the group velocity dispersion. This means that τ<;sub>0<;/sub> depends on N. The average temporal width of the solitons emerging from the instability can be arbitrarily set by suitable choice of gas pressure and pump pulse energy and duration. This theory is however only strictly valid within the approximations of the nonlinear Schrödinger equation; for few-cycle pulses a more complete model based on the full field equation must be used [4]. Using a statistical approach we explore numerically the differences between multi-cycle MI with a predicted soliton duration τ<;sub>0<;/sub> > c/ λ ~2.7 fs, and sub-cycle MI τ<;sub>0<;/sub> <; c/ λ ~2.7 fs. After running many simulations (~1000) for both cases we retrieve, at a given fibre position, the temporal location, duration and peak power of certain discrete peaks in the intensity envelope. For a predicted average soliton duration of 7 fs (multi-cycle regime) the simple analysis above works as expected (Fig. 1); N = 1 solitons are predominantly generated (dashed curve), the peak in the distribution of pulse durations being at 7 fs. Even after propagation over 3 dispersion lengths the distribution is maintained, as expected for solitons. The small deviations are likely to be due to higher order effects in these extremely short and broadband pulses.For a predicted average soliton duration of 1 fs, i.e., in the sub-cycle regime, we see that instead of an <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</i> = 1 distribution, the majority of pulses condense to a single state with duration 1.5 fs, two small distributions appearing along the <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</i> = 1 and <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">N</i> = 2 lines, corresponding respectively to half-cycle and single-cycle solitons (Fig. 2a). Upon propagation this state evolves , eventually converging to that in Fig. 2b. Remarkably, although the NLSE-based MI theory is not valid, MI-like break-up still occurs, leading to an incoherent train of pulses of duration 0.5 to 1.5 fs, with peak powers greater than 50 MW. A very broad supercontinuum is generated (Fig. 2c) and the numerical and experimental spectra agree extremely well, supporting the validity of the numerical model in this extreme case. | publication |
W1786974281 | Moisture characteristics and their point pedotransfer functions for coarse-textured tropical soils differing in structural degradation status | The effect of soil structure on hydraulic pedotransfer functions (PTFs) in tropical soils with similar mineralogy and texture has not been well documented. Structurally contrasting soils from representative locations in southeastern Nigeria were analyzed for moisture retention at 0, 6, 10, 33, 100, 300 and 1500 kPa among other properties. They were grouped by depth (topsoils or subsoils) and also by their structural degradation status into low- and high-stability soils, corresponding to organic matter (OM):[silt + clay] of 7.5%, respectively. Soil depth and structural stability influenced the soil moisture characteristic curves. The data were fitted to three tropical point PTFs, but none of them proved appropriate for predicting moisture retention in the soils. We therefore derived new ones using multiple linear stepwise regressions before and after the dataset grouping and compared their performances by means of cross-validation. Moisture retention in the soils (sand content, 73.2–93.8%) could not be calibrated from texture and OM concentration alone, until when bulk density, total porosity and microporosity were included among the regressors. Microporosity's role was particularly outstanding at all matric potentials but the 1500 kPa. The ensuing PTFs represent a good fit for the soil moisture retention data. The two grouping strategies resulted in lower SE of the estimates in some cases, but this did not enhance the performances of the concerned PTFs. At the 1500 kPa, however, the PTF incorporating all datasets performed better than separate PTFs for topsoils/subsoils but worse than the one for high-stability soils. Information on soil structure can therefore benefit PTF derivation for kaolinite-dominated, coarse-textured tropical soils at all the matric potentials considered. Copyright © 2012 John Wiley & Sons, Ltd. | publication |
W2008043506 | High Plasma Efavirenz Concentration and CYP2B6 Polymorphisms in Thai HIV-1 Infections | Efavirenz is mainly metabolized by cytochrome P450 2B6 (CYP2B6). This study aimed to examine the frequencies of CYP2B6 and the association between CYP2B6 polymorphisms and plasma efavirenz concentrations in an HIV-1 infected Thai population. Mid-dose plasma efavirenz concentration was determined at 12 weeks following the initiation of an antiretroviral therapy (tenofovir, lamivudine and efavirenz) in 100 Thai adults with HIV-1 infection using high-performance liquid chromatography. Candidate CYP2B6 polymorphisms (c.64C>T, c.499C>G, c.516G>T, c.785A>G, c.1375A>G, c.1459C>T) were conducted by real-time PCR-based allelic discrimination. The most frequent polymorphisms among this cohort were the CYP2B6 c.785A>G and c.516G>T, which had a frequency of 0.36 and 0.32, respectively. From the cases observed, two single nucleotide polymorphisms (SNPs) (c.516G>T and c.785A>G) were significantly associated with high efavirenz plasma levels (p < 0.05). The most frequent haplotypic combinations were *1/*6, *1/*1, *1/*2 and *6/*6 at a frequency of 42.0%, 32.0%, 8.0% and 7.0%, respectively. Increased plasma concentrations of efavirenz were present in individuals with CYP2B6 *6/*6 [7.210 mg/L; interquartile range (IQR), 5.020-9.260] when compared to those with CYP2B6*1/*1 (1.570 mg/L; IQR, 1.295-2.670), p < 0.001. In our study, the impact of SNPs which are correlated with a high level of efavirenz plasma concentrations was found. The genetic configuration of SNPs which are associated with high plasma efavirenz levels may be useful in optimizing the efavirenz dose that is used in HIV-1 infected patients. | publication |
W64332451 | Discriminative Hierarchical Part-Based Models for Human Parsing and Action Recognition | We consider the problem of parsing human poses and recognizing their actions in static images with part-based models. Most previous work in part-based models only considers rigid parts (e.g., torso, head, half limbs) guided by human anatomy. We argue that this representation of parts is not necessarily appropriate. In this paper, we introduce hierarchical poselets--a new representation for modeling the pose configuration of human bodies. Hierarchical poselets can be rigid parts, but they can also be parts that cover large portions of human bodies (e.g., torso + left arm). In the extreme case, they can be the whole bodies. The hierarchical poselets are organized in a hierarchical way via a structured model. Human parsing can be achieved by inferring the optimal labeling of this hierarchical model. The pose information captured by this hierarchical model can also be used as a intermediate representation for other high-level tasks. We demonstrate it in action recognition from static images. | publication |
EP 8700291 W | PROCESS AND SYSTEM FOR BURNING A LIQUID OR GASEOUS FUEL IN THE COMBUSTION CHAMBER OF AN INTERNAL COMBUSTION ENGINE | Process and system for burning a liquid or gaseous fuel in the presence of air or another oxidizing agent, involving the use of water in the combustion chamber (12) of an internal combustion engine, in particular a reciprocating or rotary piston engine. To reduce the consumption of fuel and emission of pollutants, and to improve efficiency when using low-octane fuels, in particular regular grade petrol, or acetylene as the fuel, water is directly fed, in a quantity dependent on operation, into the combustion chamber (12) during one or several selected phases, especially throughout the entire operation, in such a way that a continuing "primary combustion" of fuel/air takes place just under the critical "Knocking" temperature (Tc), which at each point of combustion initiates a "secondary combustion" of the admixed water. The "secondary combustion" effects an entirely smooth continuing combustion inside the combustion chamber (12). | patent |
223704 | Micro-, meso-, and macro-level determinants of educational inequalities: an interdisciplinary approach | Governments across the world recognize the right of the child to education on the basis of equal opportunity. Education shall allow children to develop their talents, abilities, and personality, and the principle of equal opportunity shall guarantee the eradication of any kind of discrimination. Accordingly, in a meritocratic system, educational outcomes should be directly related to individual merit. However, research shows that ascriptive (‘non-merit’) characteristics such as social origin also play a role in shaping educational outcomes. For instance, across OECD countries, no more than one out of five students from families with a low educational background attains a degree in tertiary education, as opposed to two thirds of students from families with at least one parent with tertiary education. These disparities are often considered as a measure of inequality of opportunity and therefore deserve attention from both scientists and policymakers. To date, despite an increasing body of knowledge on educational inequalities, only very little research exists on additive and interactive effects of micro-, meso-, and macro-level characteristics on educational inequalities. Against this background, the proposed research project shall use an interdisciplinary analytic framework to assess how micro-level psychological characteristics (e.g., self-efficacy and motivation), meso-level (family and school) characteristics, and macro-level characteristics (educational policies and wider societal contexts) affect social inequalities in education, and whether their distinct combinations shape inequalities. Data will be derived from standardized cross-national surveys (PISA, TIMSS) as well as from longitudinal cohort studies (e.g., BCS70, MCS, YDS). A variety of state-of-the-art research methods will be employed, including multilevel analysis and growth curve modeling, to generate scientific evidence and extend theory on major determinants of social disparities in education. | project/european |
W2105170239 | Functionalized Nanoscale Micelles with Brain Targeting Ability and Intercellular Microenvironment Biosensitivity for Anti-Intracranial Infection Applications | Due to complication factors such as blood-brain barrier (BBB), integrating high efficiency of brain target ability with specific cargo releasing into one nanocarrier seems more important. A brain targeting nanoscale system is developed using dehydroascorbic acid (DHA) as targeting moiety. DHA has high affinity with GLUT1 on BBB. More importantly, the GLUT1 transportation of DHA represents a "one-way" accumulative priority from blood into brain. The artificial micelles are fabricated by a disulfide linkage, forming a bio-responsive inner barrier, which can maintain micelles highly stable in circulation and shield the leakage of entrapped drug before reaching the targeting cells. The designed micelles can cross BBB and be further internalized by brain cells. Once within the cells, the drug release can be triggered by high intracellular level of glutathione (GSH). Itraconazole (ITZ) is selected as the model drug because of its poor brain permeability and low stability in blood. It demonstrates that the functionalized nanoscale micelles can achieve highly effective direct drug delivery to targeting site. Based on the markedly increased stability in blood circulation and improved brain delivery efficiency of ITZ, DHA-modified micelles show highly effective in anti-intracranial infection. Therefore, this smart nanodevice shows a promising application for the treatment of brain diseases. | publication |
Q10861 | Development of internal reference material to control the quality of outputs of electromaterial recycling products | The aim of the project is to develop a reference material for the control of chemical analysis of metal concentrates. This material will be used to check the relevance of degradation techniques, analytical procedures and follow-up results, as well as commercial certified reference materials, in monitoring the quality of production and at the same time for checking the accuracy of data generated in the laboratories of business partners. Ref. material should better reflect composition of composites than commercial reference materials intended for metallurgy. a. | project/regional |
219461 | Atlas of renaissance antiquarianism | ATRA - Atlas of Renaissance Antiquarianism is a digital system that will map the circulation of antiquarian learning in sixteenth-century Europe. Its purpose is to contribute to the promotion of new knowledge on antiquarian studies in the Renaissance and demonstrate how the antiquarian approach – that based the growth of thought on documented sources and empirical evidence – played a primary role in the evolution of the entire cultural/intellectual life of Early Modern times. The main intent is to allow the interconnection of data that otherwise would probably never come into contact and to bring to the surface issues not yet bridled in rigid classifications. This will enable the discovery of new cultural itineraries and convergences in Renaissance scholarship; trace the paths that led to parallel or independent ideas; and uncover new trends of thought that can help us better understand the evolution of European civilization and spirit.
Innovative and revolutionary interpretative pathways will come to light, conferring a renewed awareness of the concept of Renaissance antiquarianism and offering to the entire academic community further instruments to investigate the History of Ideas.
This project is essential for Acciarino’s personal career growth and for the global development of this field of study. Thanks to this training and to his entire course of studies that has allowed him to grow as a researcher and as an academic scholar at a European level, he will also be able to cooperate with cutting-edge institutions of excellence for multidisciplinary research in Renaissance studies and develop competencies in digital humanities that will render his professional profile technologically up-to-date and more competitive.
Through the Renaissance network created between UNIVE and University of Toronto, dialogue, research and innovation will gradually grow and become a guiding light for the entire academic community. | project/european |
W1818688782 | Pathogen surveillance in wild bottlenose dolphins Tursiops truncatus | The number and prevalence of diseases is rapidly increasing in the marine ecosystem. Although there is an increase in the number of marine diseases observed world-wide, current understanding of the pathogens associated with marine mammals is limited. An important need exists to develop and apply platforms for rapid detection and characterization of pathogenic agents to assess, prevent and respond to disease outbreaks. In this study, a broad-spectrum molecular detection technology capable of detecting all sequenced microbial organisms, the Lawrence Livermore Microbial Detection Array, was used to assess the microbial agents that could be associated with wild Atlantic dolphins. Blowhole, gastric, and fecal samples from 8 bottlenose dolphins were collected in Charleston, SC, as part of the dolphin assessment effort. The array detected various microbial agents from the dolphin samples. Clostridium perfringens was most prevalent in the samples surveyed using the microarray. This pathogen was also detected using microbiological culture techniques. Additionally, Campylobacter sp., Staphylococcus sp., Erwinia amylovora, Helicobacter pylori, and Frankia sp. were also detected in more than one dolphin using the microarray, but not in culture. This study provides the first survey of pathogens associated with 3 tissue types in dolphins using a broad-spectrum microbial detection microarray and expands insight on the microbial community profile in dolphins. | publication |
W1966293291 | Lack of association between deficient mismatch repair expression and outcome in endometrial carcinomas of the endometrioid type | Endometrial carcinomas of the endometrioid type (EEC) are associated with a good prognosis. However, about 20% of them recur and new prognostic markers are needed. Microsatellite instability (MSI), associated with mismatch repair (MMR) deficiency, is a frequent alteration in EECs that has been associated with prognosis. However, its prognostic impact on EECs remains unclear. The aim of the present study was to clarify the relationship between MMR deficiency and outcome in a large cohort of well classified EECs.A total of 212 EEC samples were analyzed by immunohistochemistry for the MMR genes MLH-1, MSH-2, MSH-6 and PMS-2. Kaplan-Meier survival analysis and log-rank tests were performed to study the prognostic significance of dMMR taking into account clinical and pathological parameters.We observed no association between MMR deficiency and OS or PFS in our 212 EEC patients (p-value=0.6565 and 0.4380, respectively). When we performed the analysis in different FIGO-stage groups, we did not find association between MMR and OS or PFS in stages I, I/II or III/IV. When we analyzed the specific group of patients with lymphatic invasion separately, MMR expression was not associated with OS or PFS either.MMR deficiency does not seem to be a good prognostic marker in endometrioid type endometrial carcinomas. | publication |