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drug_combination | What is the drug combination mentioned in the following sentence? Coadministration of vorinostat and oxaliplatin induced G2/M phase arrest , triggered caspase-dependent apoptosis , and decreased tumorigenicity both in vitro and in vivo . | vorinostat oxaliplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Randomized open trial of gentamicin and doxycycline for eradication of Bartonella quintana from blood in patients with chronic bacteremia . | gentamicin doxycycline are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The role of dual antiplatelet therapy combining aspirin and clopidogrel , is controversial . | aspirin clopidogrel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We conducted a dose-escalating study of daunorubicin combined to fixed doses of IM ( imatinib mesylate , 600 mg/d ) and cytarabine ( 200 mg/d for 7 days ) , followed by hematopoietic stem cell transplantation or maintenance therapy with single-agent IM in patients with MBC-CML at onset or after failure of therapy excluding TKIs . | daunorubicin imatinib cytarabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Combination chemo-endocrine therapy of metastatic and stage IV breast cancer with cyclophosphamide , adriamycin , prednisolone and tamoxifen (CAPT)--with special reference to management of brain and liver metastasis ] . | cyclophosphamide adriamycin prednisolone tamoxifen are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Ra ( rate of production ) was measured during infusion of variable doses of epinephrine with or without variable doses of propranolol , a competitive beta-adrenergic antagonist to isolate the alpha-adrenergic agonist effects . | epinephrine propranolol are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A 29-year-old man with juvenile myoclonic epilepsy and medically refractory GTCS on a combination of levetiracetam and topiramate was started on lacosamide adjunctive therapy with the plan to replace topiramate . | levetiracetam topiramate are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ A randomized controlled trial of immunochemotherapy using carmofur ( HCFU ) , mitomycin C and immunopotentiators in advanced gastric cancer following noncurative resection and nonresection ] . | carmofur mitomycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We thus undertook an extensive longitudinal immunologic study , including phenotypic , transcriptomic , and functional analyses , on 44 first-line and 27 relapsed/refractory patients enrolled in the GALEN trial ( Obinutuzumab Combined With Lenalidomide for Relapsed or Refractory Follicular B-Cell Lymphoma ) to test the efficacy of lenalidomide and obinutuzumab combination in patients with FL . | Obinutuzumab Lenalidomide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Nab-paclitaxel has demonstrated improved PFS and tolerability compared with standard cremophor-solubilized paclitaxel ; based on this , we examined the efficacy and safety of combining weekly nab-paclitaxel with carboplatin and bevacizumab in TNMBC . | carboplatin bevacizumab nab-paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Acute renal failure ( ARF ) occurred concomitantly with the administration of gentamicin in combination with clindamycin in three patients in whom no other known predisposing cause of ARF could be demonstrated . | gentamicin clindamycin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? To explore the role of augmenting neutrophil function in B-cell lymphoma , we conducted a phase II study evaluating the safety and clinical efficacy of pegfilgrastim and rituximab in low-grade CD20 | pegfilgrastim rituximab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The aim of this paper is to compare intravitreous aflibercept versus dexamethasone implant followed by aflibercept ( sequential treatment group ) in patients with diabetic macular edema ( DME ) . | dexamethasone aflibercept are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients with advanced solid tumors received standard doses of paclitaxel and carboplatin on day 1 followed by either 0.1 mg/Kg or 0.2 mg/Kg CP-870,893 on day 3 ( Schedule A ) or day 8 ( Schedule B ) , repeated every 21 d. | paclitaxel carboplatin CP-870,893 are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In a 52-week , open-label , multicenter , extension study , HDL-C , TG , and LDL-C levels continued to improve , or were maintained , during combination therapy with once-daily fenofibric acid 135 mg plus a moderate-dose statin ( atorvastatin 40 mg , rosuvastatin 20 mg , or simvastatin 40 mg ) . | fenofibric atorvastatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? To compare the safety and efficacy of 2 doses of lamivudine given in combination with zidovudine with continued zidovudine monotherapy . | lamivudine zidovudine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Bradykinin enhanced the effect of carbachol by about 10 - 15 % . | Bradykinin carbachol are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Here , we report that combinatorial treatment using EGFRis , such as gefitinib or erlotinib , with PI3K/AKT pathway inhibitors ( PI3K/AKTis ) demonstrated a synergistic , anti-proliferative effect in cell lines of the basal-like ( BL ) subtype , a subtype of TNBC . | gefitinib PI3K/AKTis are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients received gemcitabine 1000 mg/m² intravenously on days 1 and 8 , capecitabine 1300 mg/m² oral daily from day 1 to 14 , and dovitinib oral daily 5 days on and 2 days off , every 21-day cycle . | gemcitabine capecitabine dovitinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A reduced dose of oxaliplatin 105 mg/m(2 ) on day 1 with doxorubicin at 20 mg/m(2)/dose on days 1 - 3 was well tolerated . | oxaliplatin doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A total of 80 patients were randomized , including 44 to the combination group ( tamsulosin 0.4 mg and tolterodine early release 4 mg ) and 36 to the monotherapy group ( tamsulosin 0.4 mg and placebo ) . | tamsulosin tolterodine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment of rapidly progressive glomerulonephritis by extracorporeal immunoadsorption , prednisolone and cyclophosphamide . | prednisolone cyclophosphamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Doxifluridine , medroxyprogesterone acetate and cyclophosphamide ( DMpC ) combination therapy is effective against recurrent triple negative breast cancer -- a case report ] . | Doxifluridine medroxyprogesterone cyclophosphamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The levels of 3 NF-kappaB transcription factors , the activating inhibitors of NF-kappaB ( IkappaB ) kinases , and the NF-kappaB target matrix metalloproteinase 9 ( MMP9 ) were assessed by immunohistochemistry in specimens of ovarian cancer that were obtained at diagnosis from a cohort of 33 patients who subsequently received combined paclitaxel , cisplatin , and cyclophosphamide . | paclitaxel cyclophosphamide cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Randomized Phase II Trial of Seribantumab in Combination with Erlotinib in Patients with EGFR Wild-Type Non-Small Cell Lung Cancer . | Seribantumab Erlotinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Trabectedin in combination with pegylated liposomal doxorubicin ( PLD ) has been fully available privately in the UK since 2009 for treating patients with ROC . | Trabectedin doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Estramustine has been shown to potentiate the antimicrotubule effects of vinblastine . | Estramustine vinblastine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Cohort 7 ( gemcitabine 600 mg/m/wk and carboplatin 2 AUC ) showed 4 dose limiting toxicities : 2 grade 3 esophagitis ; one grade 3 febrile neutropenia ; and one grade 4 neutropenia . | gemcitabine carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment with IFN-α plus bevacizumab or standard targeted therapy ( sunitinib ) may lead to similar one-year overall mortality ( RR 0.37 , 95 % CI 0.13 to 1.08 ; 1 study ; 83 participants ; low-quality evidence ) and AEs of grade 3 or greater ( RR 1.18 , 95 % CI 0.85 to 1.62 ; 1 study ; 82 participants ; low-quality evidence ) . | bevacizumab IFN-α are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The possibility that verapamil might increase the sensibility of colorectal carcinomas to doxorubicin was studied in 24 patients without previous cytotoxic chemotherapy . | verapamil doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Twenty-six patients presenting with advanced breast cancer with a taxane- and vinorelbine-free line of chemotherapy were included and treated with vinorelbine ( 20 mg/m2 on D1 , D15 ) , followed by paclitaxel ( 175 mg/m2 on D1 ) , every 3 weeks . | vinorelbine paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Relationships between heart rate , exercise tolerance and cardiac output in atrial fibrillation : the effects of treatment with digoxin , verapamil and diltiazem . | digoxin verapamil diltiazem are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Oxaliplatin , which is effective for colorectal cancer ( CRC ) in combination with 5-fluorouracil ( 5-FU ) and leucovorin ( LV ) , is widely used for metastatic CRC . | Oxaliplatin leucovorin 5-fluorouracil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The cytotoxicity of sequential combinations of a taxoid [ paclitaxel ( TAX ) or docetaxel ( TXT ) ] with a vinca alkaloid [ vinorelbine ( NVB ) ] was compared in differentiated and undifferentiated HT29-D4 cells . | paclitaxel vinorelbine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Time to first deterioration was delayed with nivolumab + ipilimumab versus chemotherapy across LCSS and EQ-5D summary measures . | nivolumab ipilimumab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? In the present study , we investigated the effect atorvastatin , celecoxib and tipifarnib in combination on proliferation and apoptosis in Panc-1 sphere-forming cells . | atorvastatin celecoxib tipifarnib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Recipients received the dual endothelin-1 ( ET-1 ) receptor blocker , bosentan ( 100 mg/kg ) , the angiotensin-converting enzyme ( ACE ) inhibitor , ramipril ( 5 mg/kg ) , bosentan plus ramipril ( doses as just noted ) or vehicle . | bosentan ramipril are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? After surgery , she received a sequential chemotherapy , ie , intraabdominal injection of carboplatin ( CBDCA 300 mg/m2 ) and div administration of paclitaxel ( PTX 180 mg/m2 ) as a standard regimen for advanced ovarian cancer . | carboplatin paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? To study the release of free endotoxin from Escherichia coli exposed to varying concentrations of the penicillin-binding protein ( PBP ) 3-specific beta-lactam antibiotic cefuroxime , the aminoglycoside tobramycin , and a combination of the two , and to test the relationship between bacterial killing rate and endotoxin release . | cefuroxime tobramycin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? As CDK7 inhibitors are currently under clinical evaluation in patients , our data suggest the addition of the TKI ponatinib or lapatinib in CDK7 inhibitor clinical trials in patients . | lapatinib CDK7 inhibitor are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? An effective treatment for operable breast cancer , NCT with epirubicin plus paclitaxel results in significant downstaging or eliminating of primary tumors in breast cancer , thus expanding the indication of breast conservation therapy . | epirubicin paclitaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Carboplatin and etoposide for recurrent malignant glioma following surgical and radiotherapy failure : A clinical study conducted at the Northern Israel Oncology Center . | Carboplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? ABC transporter inhibition plus dexamethasone enhances the efficacy of CED dasatinib , resulting in enhanced tumor cellular apoptosis and improved survival in H3.3K27 M mutant DIPG . | dexamethasone dasatinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Those who received prednisone alone could have mitoxantrone added after 6 weeks if there was no improvement in pain . | prednisone mitoxantrone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Results of a prospective phase 2 study combining imatinib mesylate and cytarabine for the treatment of Philadelphia-positive patients with chronic myelogenous leukemia in chronic phase . | imatinib cytarabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patient-reported outcomes of patients with advanced biliary tract cancers receiving gemcitabine plus capecitabine : a multicenter , phase II trial of the Swiss Group for Clinical Cancer Research . | gemcitabine capecitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? as neoadjuvant chemotherapy , and two cycles of doxorubicin/cisplatin and ifosfamide , and two cycles of high-dose methotrexate ( 10 - 12 g/m(2 ) ) were given post-operatively . | doxorubicin/cisplatin ifosfamide methotrexate are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Reported is a case of a 58-year-old female treated in the past with cytostatics and rituximab for follicular lymphoma , in whom HBV infection was detected during a follow-up of the contacts of her partner diagnosed with acute viral hepatitis B. At the beginning , the patient had a very high serum level of HBV DNA ( 4.3 × 108 IU/mL ) and therefore she was treated with combined antiviral therapy ( lamivudine and tenofovir ) . | lamivudine tenofovir are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients with wild-type KRAS exon 2 mCRC previously treated with fluorouracil- , oxaliplatin- and irinotecan-based chemotherapies were randomised ( 1:1 ) to either panitumumab plus irinotecan ( panitumumab arm ) or cetuximab plus irinotecan ( cetuximab arm ) . | panitumumab irinotecan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Epirubicin , oxaliplatin , and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer ( REAL3 ): | Epirubicin oxaliplatin capecitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In 2005 , after a significant disease-free survival benefit was reported for letrozole as compared with tamoxifen , a protocol amendment facilitated the crossover to letrozole of patients who were still receiving tamoxifen alone ; Cox models and Kaplan-Meier estimates with inverse probability of censoring weighting ( IPCW ) are used to account for selective crossover to letrozole of patients ( n=619 ) in the tamoxifen arm . | letrozole tamoxifen are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? CEA response is associated with tumor response and survival in patients with KRAS exon 2 wild-type and extended RAS wild-type metastatic colorectal cancer receiving first-line FOLFIRI plus cetuximab or bevacizumab ( FIRE-3 trial ) . | FOLFIRI cetuximab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The Tamoxifen Exemestane Adjuvant Multinational ( TEAM ) phase 3 trial was conducted in hospitals in nine countries . | Tamoxifen Exemestane are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients used 2.16 ( range 0.0 - 6.3 ) formoterol and 2.34 ( range 0.1 - 7.5 ) terbutaline relief inhalations x day(-1 ) . | formoterol terbutaline are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Preoperative chemotherapy with FLOT ( 5-FU , leucovorin , oxaliplatin and docetaxel ) without radiation therapy is the standard treatment in the West . | 5-FU leucovorin oxaliplatin docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Digoxin sensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine via inhibiting Nrf2 signaling pathway . | Digoxin gemcitabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Tumor suppression was further enhanced when rapamycin was combined with 5-fluorouracil and/or oxaliplatin . | rapamycin 5-fluorouracil oxaliplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Metformin inhibits obesity but has no effect in reducing myocardial hypertrophy caused by Rosiglitazone . | Metformin Rosiglitazone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The primary endpoint of this study was to determine the maximal tolerated dose of the combination of dose-escalating curcumin and standard dose of docetaxel chemotherapy in advanced and metastatic breast cancer patients . | curcumin docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This case highlights the potential efficacy of combining nivolumab and regorafenib in the treatment of SBAs . | nivolumab regorafenib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Cutaneous T-cell lymphoma-like drug eruption in an HIV-positive patient taking vancomycin and rifampin . | vancomycin rifampin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Our findings suggest that roflumilast reduces exacerbations and hospital admissions in patients with severe chronic obstructive pulmonary disease and chronic bronchitis who are at risk of frequent and severe exacerbations despite inhaled corticosteroid and longacting β2 agonist therapy , even in combination with tiotropium . | roflumilast tiotropium are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Induction chemotherapy with cisplatin , doxorubicin , and cyclophosphamide ( CAP ) in a combined modality approach for locally advanced and inflammatory breast cancer . | cisplatin doxorubicin cyclophosphamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Hypertensive rats in separate groups were treated with either candesartan ( 1 mg/kg body weight ) alone or a combination of candesartan ( 1 mg/kg body weight ) and rofecoxib ( 10 mg/kg body weight ) orally and daily for 6 weeks . | candesartan rofecoxib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The highest weight gain in the cyclophosphamide , methotrexate and fluorouracil group was 2·9 kg ( 5 % ) vs. 0·9 kg ( 1 % ) in the anthracycline-based group . | cyclophosphamide methotrexate fluorouracil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment of relapsed/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma with everolimus ( RAD001 ) and alemtuzumab : a Phase I/II study . | everolimus alemtuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Capecitabine and oxaliplatin have been shown to be as effective as fluorouracil and cisplatin , respectively . | Capecitabine oxaliplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? To compare cardiopulmonary and sedative effects following administration of dexmedetomidine alone or with butorphanol , methadone , morphine or tramadol in healthy sheep . | dexmedetomidine methadone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We found that melatonin in combination with all-trans retinoic acid and somatostatin potentiated the effects of melatonin alone on MCF-7 cell viability and growth inhibition ; this phenomenon was associated with altered conductance through Ca²⁺ and voltage-activated K⁺ ( BK ) channels , and with substantial impairments of Notch-1 and epidermal growth factor (EGF)-mediated signaling . | melatonin all-trans retinoic acid somatostatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? It was concluded that cytosine arabinoside in combination with vincristine and prednisone is an effective but toxic antileukemic regimen which did not produce a major improvement in remission duration . | cytosine arabinoside vincristine prednisone are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Celecoxib induced a synergistic or an additive cytotoxic effect in combination with doxorubicin , etoposide , irinotecan or vincristine in vitro . | Celecoxib doxorubicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment of GIST882-R with imatinib in combination with gefitinib , an EGFR inhibitor , partially prevented cell growth , implying that EGFR may be involved in acquisition of secondary imatinib resistance in GIST . | imatinib gefitinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This is the first paper suggesting the possibility of combination treatment of tamoxifen with risperidone in breast cancer patients , providing a conceivable resolution of tamoxifen-induced side effects without interfering the efficacy of tamoxifen against breast cancer . | tamoxifen risperidone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Amoxicillin , erythromycin , and levofloxacin at supra-MIC concentrations were very active against planktonic cells of 3 selected strains but lower on biofilm-associated organisms in 2 strains and null against the third . | Amoxicillin erythromycin levofloxacin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A double-blind , parallel , placebo-controlled study was performed to assess the efficacy of a combination drug product containing the antihistamine , triprolidine , and the sympathomimetic , pseudoephedrine , in the treatment of allergic rhinitis . | triprolidine pseudoephedrine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? After surgery , 1,384 patients were randomly assigned to receive epirubicin plus cyclophosphamide ( EC ; 90 and 600 mg/m(2 ) , respectively , × four cycles ) , followed by docetaxel ( 100 mg/m(2 ) × four cycles ; EC-T ) or epirubicin plus docetaxel ( ET ; 90 and 75 mg/m(2 ) , respectively , × four cycles ) , followed by capecitabine ( 1,250 mg/m(2 ) twice a day on days 1 to 14 , × four cycles ; ET-X ) ; all regimens were given every 3 weeks . | epirubicin cyclophosphamide docetaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This prospective study recruited 152 patients with locally advanced breast cancer who underwent four-cycle weekly paclitaxel plus carboplatin without trastuzumab . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? High response rate and acceptable toxicity of a combination of rituximab , vinorelbine , ifosfamide , mitoxantrone and prednisone for the treatment of diffuse large B-cell lymphoma in first relapse : results of the R-NIMP GOELAMS study . | rituximab vinorelbine ifosfamide mitoxantrone prednisone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A second complete remission was obtained with RFC chemotherapy regimen ( rituximab , fludarabine , and cyclophosphamide ) . | rituximab fludarabine cyclophosphamide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A favourable response to chemotherapy can be expected in up to 60 % of patients receiving a combination of streptozocin plus doxorubicin , and in up to 40 % of patients receiving dacarbazine . | streptozocin doxorubicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This phase II study was conducted to establish whether induction chemotherapy with carboplatin ( CBDCA ) and paclitaxel ( PTX ) plus bevacizumab prior to surgery reduces the risk of progression . | carboplatin paclitaxel bevacizumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients with clinically localized , intermediate- or high-grade non-Hodgkin 's lymphoma usually receive initial treatment with a doxorubicin-containing regimen such as cyclophosphamide , doxorubicin , vincristine , and prednisone ( CHOP ) . | cyclophosphamide doxorubicin vincristine prednisone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? To evaluate the effects of a fixed combination of olmesartan/amlodipine compared with olmesartan or amlodipine alone on some parameters of endothelial damage in diabetic , hypertensive patients . | olmesartan amlodipine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Numerous phase II and III clinical trials have demonstrated a higher activity of combined gemcitabine plus docetaxel schedules against non-small cell lung cancer ( NSCLC ) than that of both agents in monotherapy . | gemcitabine docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? While 5-fluorouracil used as single agent in patients with metastatic colorectal cancer has an objective response rate around 20 % , the administration of combinations of irinotecan with 5-fluorouracil/folinic acid or oxaliplatin with 5-fluorouracil/folinic acid results in significantly increased response rates and improved survival . | irinotecan 5-fluorouracil/folinic are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Effect of nedaplatin , 5-FU , and leucovorin combined with radiation therapy in unresectable esophageal carcinoma ] . | nedaplatin leucovorin 5-FU are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? ( 4 mg/day ) ; in group 3 , 69 patients administered metformin ( 1,000 mg/day ) and rosiglitazone ( 4 mg/day ) for 6 months , | metformin rosiglitazone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The patient was treated with dexamethasone and ethinyl estradiol with cessation of anti-hypertensive therapy . | dexamethasone ethinyl are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? When compared with the combination of amphotericin B plus flucytosine , fluconazole was similarly effective in early treatment of acute and subacute disseminated candidiasis . | amphotericin flucytosine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment of patients over 50 years of age with acute myelogenous leukemia with a combination of rubidazone and cytosine arabinoside , vincristine , and prednisone ( ROAP ) . | rubidazone cytosine arabinoside vincristine prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? To compare the therapeutic effect of α(2 ) and α(4 ) integrin-blocking antibodies to conventional inflammatory bowel disease drugs methotrexate , 5-aminosalicylic acid and azathioprine in the dextran sulphate sodium mouse colitis model . | methotrexate 5-aminosalicylic acid azathioprine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Further analyses demonstrated that gemcitabine could significantly interfere with the cytotoxic effects of paclitaxel on both mitotic arrest and apoptotic cell death unless paclitaxel is administered before gemcitabine . | paclitaxel gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Molecular targeting of Aurora A by curcumin restores chemosensitivity by increasing the efficacy of doxorubicin in breast cancer. | curcumin doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma . | Daratumumab Lenalidomide Dexamethasone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Randomized phase II trial of carboplatin and paclitaxel with or without lonafarnib in first-line treatment of epithelial ovarian cancer stage IIB-IV . | carboplatin paclitaxel lonafarnib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? One subject who received oxaprozin for 12 days and , in addition , aspirin for the last five days developed a rash that subsided after both drugs were discontinued ; one subject treated with aspirin experienced tinnitus . | oxaprozin aspirin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? To determine the long-term tolerability of prophylactic administration of pyrazinamide and levofloxacin in patients possibly exposed to multidrug-resistant tuberculosis ( MDRTB ) after undergoing solid organ transplantation . | pyrazinamide levofloxacin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Additive effect of the combination of griseofulvin and ketoconazole against Microsporum canis in vitro . | griseofulvin ketoconazole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Aprepitant plus ondansetron may increase acute-CR , may have benefit regarding CINV 's effect on QoL , and is safe for 5-day temozolomide compared to ondansetron . | Aprepitant ondansetron are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Finally , a further synergistically improved myeloma cell lysis with the daratumumab-IPH2102 combination was observed by adding lenalidomide , which suggests that more effective treatment strategies can be designed for multiple myeloma by combining daratumumab with agents that independently modulate natural killer cell function . | lenalidomide daratumumab are the drug combinations. No need for context. It is a POS combination. |