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drug_combination | What is the drug combination mentioned in the following sentence? These data suggest that vorinostat and doxorubicin may induce procoagulant activity in vessels through apoptosis of tumor cells and through phosphatidylserine exposure and/or tissue factor expression on vascular endothelial cells . | vorinostat doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Based on encouraging results of previous combination regimens , we used a combination of VM26 , ifosfamide , methyl GAG , mitoxantrone ( or adriamycin ) , high-dose ( HD ) methotrexate and HD Ara C to treat 18 patients with relapsed or refractory NHL . | VM26 ifosfamide methyl GAG , mitoxantrone methotrexate Ara C are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We treated this patient with six cycles of CHOEP ( Cyclophosphamide , Doxorubicin , Vincristine , Etoposide , and Prednisone ) chemotherapy . | Cyclophosphamide Doxorubicin Vincristine Etoposide Prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? One study evaluated gemcitabine with gemcitabine and pertuzumab . | gemcitabine pertuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We conclude that the combination of thiotepa , 5FU , and leucovorin had significant myelotoxicity and do not recommend its routine use in the treatment of metastatic breast cancer . | thiotepa 5FU leucovorin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Forty-two patients with stage III to IV resectable HNSCC and nasopharyngeal tumors received induction chemotherapy with two courses of cisplatin ( 20 mg/m2/d continuous infusion [ CI ] ) , fluorouracil ( 800 mg/m2/d CI ) , and leucovorin ( 500 mg/m2/d CI ; PFL ) for 4 days followed by concurrent therapy with cisplatin ( 100 mg/m2/d on days 1 and 22 ) and approximately 70 Gy of external-beam radiotherapy . | cisplatin fluorouracil leucovorin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Will a combination of l-leucine with low-dose metformin and sildenafil produce a novel synergistic interaction that reduces body weight ? | l-leucine metformin sildenafil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Combinatory activity of linezolid and levofloxacin with antituberculosis drugs in Mycobacterium tuberculosis . | linezolid levofloxacin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Canadian clinical guidelines recommend the use of the combination of tamsulosin and dutasteride for men with moderate/severe symptoms associated with BPH and enlarged prostate volume . | tamsulosin dutasteride are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The present study was designed to test the effects of chronic combined treatment with low doses of an angiotensin converting enzyme inhibitor ( perindopril ) and of the diuretic indapamide in spontaneously hypertensive rats ( SHR ) . | perindopril indapamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A phase 3 trial of azacitidine versus a semi-intensive fludarabine and cytarabine schedule in older patients with untreated acute myeloid leukemia . | fludarabine cytarabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Five other treatments closely followed ( dabrafenib [ HR PFS : 0.30 ] , nivolumab plus ipilimumab [ HR PFS : 0.34 ] , vemurafenib [ HR PFS : 0.38 ] , nivolumab [ HR PFS : 0.42 ] and pembrolizumab [ HR PFS : 0.46 ] ) . | nivolumab ipilimumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients with newly diagnosed , locally advanced stage III or IV SCCHN received 4 weekly doses of carboplatin ( area under the curve , 1.5 ) and paclitaxel ( 45 mg/m(2 ) ) concurrently with concomitant boost radiation consisting of 72 grays in 42 fractions over 6 weeks ( every day for 18 days , twice a day for 12 days ) ( grading determined according to the TNM staging system ) . | carboplatin paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Phase 1b trial of docetaxel , prednisone , and pazopanib in men with metastatic castration-resistant prostate cancer . | docetaxel prednisone pazopanib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Growth inhibition of cloned promastigotes showed that the films have enough releasing capacity and in vivo system , the films containing paromomycin and gentamicin was able to reduce the lesion size and induced complete cure in 80 % of the mice but relapse was seen in 60 % of the cured mice and overall 50 % cure rate was seen during 20 weeks period of the study . | paromomycin gentamicin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Management and outcome : The patient was initially treated with bortezomib and dexamethasone for the myeloma . | bortezomib dexamethasone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? We retrospectively evaluated 52 metastatic renal cell carcinoma patients who were treated with nivolumab plus ipilimumab between August 2015 and January 2020 . | nivolumab ipilimumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Microdialysis-based pharmacokinetic studies demonstrated that administration of the P-gp inhibitor cyclosporin A resulted in increased brain levels of escitalopram without altering plasma escitalopram levels in the rat , thereby showing that P-gp restricts escitalopram transport across the blood-brain barrier ( BBB ) in vivo . | cyclosporin escitalopram are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of mezlocillin and an aminoglycoside produced synergy more often than did carbenicillin plus an aminoglycoside . | mezlocillin aminoglycoside are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Eligible patients ( n = 17 ) were divided into 2 groups receiving a combined chemotherapy of intravenous cisplatinum ( 70 mg/m2 ) and cyclophosphamide ( 700 mg/m2 ) with or without the addition of Lenograstim . | cisplatinum cyclophosphamide Lenograstim are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Ifosfamide at 12 g/m2 was administered by intravenous continuous infusion over 3 days , and doxorubicin 60 mg/m2 was administered as an intravenous bolus injection on day 1 . | Ifosfamide doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A Randomized , Double-blind , Placebo-controlled Trial of Celecoxib Augmentation of Sertraline in Treatment of Drug-naive Depressed Women : A Pilot Study . | Celecoxib Sertraline are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In seven patients with type B insulin resistance , standardized treatment with rituximab , cyclophosphamide , and pulse steroids results in remission of the disease . | rituximab cyclophosphamide steroids are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The purpose of this study was to determine the fertility rates following treatment by means of the BEACOPP regimen ( regular and escalated ) ( bleomycin , etoposide , doxorubicin , cyclophosphamide , vincristine , procarbazine , prednisone ) as compared to the ABVD regimen ( doxorubicin , vinblastine , dacarbazine , bleomycin ) in Hodgkin lymphoma patients under the age of 40 at the time of treatment . | bleomycin etoposide doxorubicin cyclophosphamide vincristine procarbazine prednisone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The positive inotropism of DPDPE was abrogated in animals pretreated with propranolol , CGRP(8 - 37 ) , or combined propranolol+CGRP(8 - 37 ) . | DPDPE propranolol are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A case of Scedosporium apiospermum infection after BMT , treated initially with amphotericin B ( total dose of 2.5 g ) and then with itraconazole ( for 25 days ) , is reported here . | amphotericin itraconazole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Thymidine Phosphorylase/β-tubulin III expressions predict the response in Chinese advanced gastric cancer patients receiving first-line capecitabine plus paclitaxel . | capecitabine paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Modeling of the pharmacokinetic/pharmacodynamic interaction between irbesartan and hydrochlorothiazide in normotensive subjects . | irbesartan hydrochlorothiazide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In Group IV , the augmentation of Pdi by olprinone was abolished in the fatigued diaphragm with an infusion of nicardipine . | olprinone nicardipine are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? In a 71 years-old patient , a severe therapy-resistant depressive episode without psychotic symptoms was successfully treated by a combination of paroxetine and risperidone . | paroxetine risperidone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? While there is no standard of care for PBL , current recommendations include dose-adjusted EPOCH ( etoposide , vincristine , doxorubicin , cyclophosphamide , and prednisone ) , with or without bortezomib . | etoposide vincristine doxorubicin cyclophosphamide prednisone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Our report of a patient with severe tardive dyskinesia ( TD ) who has been exposed to both typical antipsychotic and clozapine , olanzapine and quetiapine during a 124-week follow-up period supports the possible beneficial effect of atypical antipsychotics on pre-existing symptoms of TD . | clozapine olanzapine quetiapine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Paclitaxel plus bevacizumab in patients with chemosensitive relapsed small cell lung cancer : a safety , feasibility , and efficacy study from the Hoosier Oncology Group . | Paclitaxel bevacizumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Significantly , genes regulated by both formoterol and budesonide were overrepresented in the genome ; moreover , budesonide-plus-formoterol induced and repressed 609 and 577 mRNAs , respectively , of which ~1/3 failed the cut-off criterion for either treatment alone . | formoterol budesonide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This study aimed to investigate the therapeutic responses of lung cancer mice models with adenocarcinoma HCC827 ( gefitinib sensitive ) and HCC827R ( gefitinib resistant ) to the epidermal growth factor receptor-tyrosine kinase inhibitor erlotinib alone and in combination with the anti-angiogenesis agent bevacizumab using dynamic contrast enhanced ( DCE ) and diffusion-weighted MRI . | gefitinib erlotinib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? , olmesartan medoxomil + amlodipine + HCTZ was more effective in reducing BP and achieving BP goals than each of the dual therapies , irrespective of hypertension severity , age , sex , race or diabetes mellitus status . | olmesartan medoxomil amlodipine HCTZ are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Multiple-dose pharmacokinetics of telmisartan and of hydrochlorothiazide following concurrent administration in healthy subjects . | telmisartan hydrochlorothiazide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The objective of the current study was to determine whether adding the mammalian target of rapamycin inhibitor temsirolimus to sorafenib could improve on these results . | temsirolimus sorafenib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The authors report the case of a 4-year-old boy with a diagnosis of stage IV neuroblastoma ( NB ) , who had been treated with 6 cycles of cyclophosphamide , doxorubicin , cisplatin , and etoposide for 12 months . | cyclophosphamide doxorubicin cisplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Due to dose-limiting toxicity ( DLT ) in both patients ( elevated transaminases and thrombocytopenia ) , an additional three patients were treated on dose level -1 with trabectedin 0.7 mg/m2 plus gemcitabine 700 mg/m2 . | trabectedin gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? He accepted surgical resection with followed multi-agent chemotherapy , containing vincristine , doxorubicin , ifosfamide and etoposide . | vincristine doxorubicin ifosfamide etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The gemcitabine and mitoxantrone regimen was feasible to administer even in heavily pre-treated patients . | gemcitabine mitoxantrone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The aim of this study was to evaluate four phytocompounds ( cinnamaldehyde , citral , eugenol and geraniol ) for their in vitro inhibitory activity against pre-formed biofilms of Candida albicans alone or in combination with fluconazole and amphotericin B. These compounds were also tested at subinhibitory concentrations for their ability to inhibit biofilm formation . | cinnamaldehyde fluconazole are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Neoadjuvant trastuzumab , pertuzumab , and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer ( KRISTINE ): a randomised , open-label , multicentre , phase 3 trial . | trastuzumab pertuzumab trastuzumab emtansine pertuzumab are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Ultimately , the patient was successfully treated with combination therapy of Liposomal amphotericin B and Miltefosine without any relapse . | amphotericin Miltefosine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? However , verapamil significantly increased the sensitivity to etoposide , doxorubicin and vincristine in cells highly expressing MRP gene . | verapamil etoposide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Synergy was observed in vitro when HCT-116 cells were treated over a broad range of doses of trametinib and palbociclib . | trametinib palbociclib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Using a FOLFOXIRI ( 5-fluorouracil [ 5-FU ] , irinotecan , and oxaliplatin ) combination regimen , patients with metastatic colorectal cancer now have the possibility of longer survival , but disappointingly , with increased toxicities . | 5-FU irinotecan oxaliplatin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combinations of antibodies with targeted drugs like ibrutinib , idelalisib , or lenalidomide are expected to replace chemotherapy-based combinations for treating CLL in the near future . | antibodies ibrutinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The responses to quinine and mefloquine or halofantrine showed no correlation with each other . | quinine mefloquine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In a phase II study , we treated 26 consecutive patients with refractory advanced sarcoma with ifosfamide and etoposide combination chemotherapy . | ifosfamide etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? A case of delivery of healthy infant in breast cancer patient incidentally treated with goserelin acetate and tamoxifen during pregnancy . | goserelin acetate tamoxifen are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Treatment-naive patients with nonmetastatic N2 or N3 SCCHN were randomly assigned to CRT alone ( CRT arm ; docetaxel , fluorouracil , and hydroxyurea plus radiotherapy 0.15 Gy twice per day every other week ) versus two 21-day cycles of IC ( docetaxel 75 mg/m(2 ) on day 1 , cisplatin 75 mg/m(2 ) on day 1 , and fluorouracil 750 mg/m(2 ) on days 1 to 5 ) followed by the same CRT regimen ( IC + CRT arm ) . | docetaxel cisplatin fluorouracil are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The objective of this study was to compare the effect of sildenafil alone and sildenafil with bosentan on severity of tricuspid regurgitation and duration of hospitalization in new-borns with persistent pulmonary hypertension . | sildenafil bosentan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In Crohn 's disease in remission after 6 months of azathioprine in combination with infliximab , 63.8 % of practitioners discontinued azathioprine . | azathioprine infliximab are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Long-term outcome for men with androgen independent prostate cancer treated with ketoconazole and hydrocortisone . | ketoconazole hydrocortisone are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Randomized trial of betahistine mesilate tablets as augmentation for oxcarbazepine and carbamazepine in treating vestibular paroxysmia . | betahistine oxcarbazepine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Sorafenib in combination with gemcitabine in recurrent epithelial ovarian cancer : a study of the Princess Margaret Hospital Phase II Consortium . | Sorafenib gemcitabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Pharmacological inhibition of p70S6 K using the PI3K/mTOR inhibitor NVP-BEZ235 , the specific mTOR inhibitor Rapamycin and the specific p70S6 K inhibitor PF-4708671 potentiated Selumetinib effects in resistant cells . | Selumetinib NVP-BEZ235 are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Vinorelbine , ifosfamide and cisplatin as first-line treatment in patients with inoperable non-small cell lung cancer . | Vinorelbine ifosfamide cisplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Two large Phase III trials conducted in the Americas and across Europe , Australia , and Asia showed lower cumulative pregnancy rates in the NOMAC/E2 groups compared to the drospirenone ( DRSP ) 3 mg in combination with ethinyl estradiol ( EE ) 30 µg ( DRSP/EE ) groups but this difference was not statistically significant . | drospirenone ethinyl estradiol are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The objective was to compare the pharmacodynamic ( PD ) and pharmacokinetic ( PK ) effects of ticagrelor with clopidogrel among subjects of Hispanic ethnicity , as the PD and PK effects of antiplatelet agents among Hispanics are not specifically known . | ticagrelor clopidogrel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? For example , the renal excretion of methotrexate by glomerular filtration and tubular secretion is affected by a number of weak organic acids , such as probenecid , salicylates and penicillin , which compete for tubular secretion , resulting in delayed clearance of methotrexate . | methotrexate probenecid are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? To investigate the cardiac safety of adjuvant Non-Pegylated Liposomal Doxorubicin ( NPL-DOX ) combined to Cyclophosphamide ( CTX ) and followed by weekly Paclitaxel , in older patients ( ≥65 years ) with diagnosis of high risk breast cancer . | Doxorubicin Cyclophosphamide Paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The high incidence of imported malaria ( 0.70 % ) and the low costs of providing chemoprophylaxis resulted in a cost-benefit ratio of 0.19 for chloroquine and proguanil and 0.57 for a regimen containing mefloquine . | chloroquine proguanil are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Clinical trials suggest reduced benefit from the combination of cetuximab with oxaliplatin . | cetuximab oxaliplatin are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? L-carnitine was administered 1 h before doxorubicin injection and daily thereafter for 15 days . | L-carnitine doxorubicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Recoveries of both amino acids were increased bilaterally by local perfusion with veratridine ( 100 microM , given under halothane anaesthesia ) , pretreatment with reserpine ( 4 mg/kg , i.p . , 24 h beforehand ) , unilateral pretreatment of the medial forebrain bundle with 6-OHDA ( 8 microg/4 microl ) , and by the systemic ( 1 mg/kg , i.p . ) or bilateral intrastriatal ( 7 microg/0.5 microl under halothane anaesthesia ) administration of the dopamine D2 receptor antagonist haloperidol , but not raclopride ( 2 mg/kg , i.p . ) . | reserpine veratridine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Combined initial cyclophosphamide with repeated methylprednisolone pulse therapy for severe paraquat poisoning from dermal exposure . | cyclophosphamide methylprednisolone are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Hyper-CVAD , given in odd-number courses ( Courses 1 , 3 , 5 , and 7 ) , was alternated with methotrexate and cytarabine ( MTX/Ara-C ) , given in even-number courses ( Courses 2 , 4 , 6 , and 8) . | methotrexate cytarabine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Despite systemic chemotherapy combining pemetrexed , bevacizumab and Cisplatinum , the disease relapsed eight months later with multiple metastatic lung nodules leading to a treatment shift . | pemetrexed bevacizumab Cisplatinum are the drug combinations. No need for context. It is a NEG combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Pretreatment with NaHCO3 , NH4Cl , SKF 525A , piperonyl butoxide , progesterone , cysteamine , phenobarbital or metyrapone prior to the administration of [methyl-14C]nicotine was studied . | metyrapone [methyl-14C]nicotine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Because the mass invaded the pancreas and superior mesenteric vein as well as duodenum and the disease was disseminated to liver and peritoneum , she received palliative chemotherapy using vincristine , doxorubicin , cyclophosphamide , ifosfamide , and etoposide . | vincristine doxorubicin cyclophosphamide ifosfamide etoposide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? In HCV genotype 1 infection and F3 or F4 liver fibrosis , treatment with boceprevir or telaprevir in addition to pegylated interferon and ribavirin is recommended . | boceprevir pegylated interferon ribavirin are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of ifosfamide with oral etoposide appears to have significant but manageable toxicity and encouraging efficacy in platinum resistant ovarian cancer . | ifosfamide etoposide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? This Phase I , randomized , open-label study evaluated the gastric pH-altering effects of omeprazole , a proton pump inhibitor , and the CYP3A enzyme/P-glycoprotein (Pgp)-inhibitory effects of ritonavir , an HIV protease inhibitor , on the pharmacokinetics and safety of the hepatitis C virus ( HCV ) non-structural protein 5A ( NS5A ) inhibitor GSK2336805 in healthy male and female subjects . | omeprazole ritonavir GSK2336805 are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Phase II study of weekly paclitaxel and sorafenib as second/third-line therapy in patients with adrenocortical carcinoma . | paclitaxel sorafenib are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? This study indicates that cyclophosphamide , doxorubicin , and methotrexate are , at best , marginally active as single agents , and new drugs with more efficacy are needed before combination chemotherapy can be expected to result in any meaningful prolongation of survival in non-small cell lung cancer . | cyclophosphamide doxorubicin methotrexate are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The combined treatment of curcumin and docetaxel inhibited the proliferation and induced apoptosis significantly higher than the curcumin and docetaxel-treated group alone . | curcumin docetaxel are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Previously , a study of ours showed that the combination of dabrafenib and trametinib improves progression-free survival compared with dabrafenib and placebo in patients with BRAF Val600Lys/Glu mutation-positive metastatic melanoma . | dabrafenib trametinib are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? compared to those for rats treated with trovafloxacin or clindamycin plus gentamicin | clindamycin gentamicin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? All but one received two induction courses of the 3 day-AVI ( doxorubicin 50 mg/m(2 ) day 1 , etoposide 120 mg/m(2 ) day 1 , 2 , 3 , ifosfamide 2000 mg/m(2 ) day 1 , 2 ) regimen . | doxorubicin etoposide ifosfamide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In the phase I trial , 19 patients received bolus doxorubicin ( 50 mg/m2 ) followed after a 16-hour interval by paclitaxel ( given at dose levels ranging from 130 to 250 mg/m2 ) by 3-hour infusion every 3 weeks , for a maximum of eight cycles . | doxorubicin paclitaxel are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Exposure of LLC-PK1 cells to hydrogen peroxide ( 2.5 mM ) resulted in a significant increase in the bleomycin-detectable iron ( iron capable of catalyzing free radical reactions ) content that was prevented by cimetidine , but not ranitidine . | hydrogen peroxide cimetidine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Patients were randomly assigned 1:1 centrally to either the docetaxel , prednisone , and custirsen combination or docetaxel and prednisone alone . | docetaxel prednisone custirsen are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? [ Carboplatin and etoposide combination for the treatment of recurrent epithelial ovarian cancer ] . | Carboplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? One-hour paclitaxel plus carboplatin in the treatment of advanced non-small cell lung cancer : results of a multicentre , phase II trial . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Preliminary data combining trastuzumab with the antiangiogenic antibody bevacizumab is encouraging ; this combination will be tested in both early stage and late stage disease . | trastuzumab bevacizumab are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? A decrease in VEGF-A expression in the tumor node and salivary gland was found after monotherapy with melatonin and cyclophosphamide and , especially , after combined treatment , which proves maximum therapeutic efficiency of combined administration of chemical agents with various mechanisms of action . | melatonin cyclophosphamide are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? The combination of rituximab , bendamustine , and cytarabine ( R-BAC ) was highly active in a pilot trial of mantle cell lymphoma , but its use was restricted by high haematological toxicity . | rituximab bendamustine cytarabine are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Despite treatment with PH specific therapy ( sildenafil , ambrisentan , and epoprostenol ) , her condition worsened rapidly with acute right heart failure ( RHF ) . | sildenafil ambrisentan epoprostenol are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Data from the present study show the feasibility and tolerability of combination ixabepilone plus carboplatin , with ixabepilone administered on day 1 or on days 1 and 8 on a 21-day cycle . | ixabepilone carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Thirteen stage III B and 13 stage IV patients received intermediate doses of ifosfamide ( 1000 mg/m2 ) , carboplatin ( 120 mg/m2 ) and etoposide ( 120 mg/m2 ) given intravenously on day 1 to 3 every 4 weeks . | ifosfamide carboplatin etoposide are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The null hypothesis was there is no difference with respect to pain scores between ketorolac and iliac crest bupivacaine infusion as analgesic adjuncts to intravenous opioids . | ketorolac bupivacaine are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Etoposide in combination with low-dose CAG ( cytarabine , aclarubicin , G-CSF ) for the treatment of relapsed or refractory acute myeloid leukemia : a multicenter , randomized control trial in southwest China . | Etoposide cytarabine aclarubicin G-CSF are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? were randomized in an open-label , crossover fashion to treatment A ( dolasetron 100 mg on day 1 ) and treatment B ( dolasetron 100 mg plus aprepitant 125 mg on day 1 , aprepitant 80 mg on days 2 - 3 ) . | dolasetron aprepitant are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? The regimen of gemcitabine combined with ifosfamide and anthracycline is feasible , tolerable and effective in patients with recurrent platinum resistant/refractory epithelial ovarian cancer . | gemcitabine ifosfamide anthracycline are the drug combinations. No need for context. It is a POS combination. |
drug_combination | What is the drug combination mentioned in the following sentence? Second-line treatments consisted of cetuximab plus irinotecan for arm A , and oxaliplatin plus either 5-fluorouracil ( FOLFOX ) or capecitabine ( CapeOX ) for the control arms . | cetuximab irinotecan are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? In the UT-EC-1 cell line the growth inhibition was 72 % with paclitaxel , 54 % with carboplatin and 73 % with the combination of these compounds . | paclitaxel carboplatin are the drug combinations. Need more context. |
drug_combination | What is the drug combination mentioned in the following sentence? Several lines of evidence implicate serotonin ( 5-HT ) as the mediator of this enhancement : ( 1 ) Tranyclypromine-enhanced nicotine reinforcement was blocked by the 5-HT₂ receptor antagonists , ritanserin and ketanserin ; ( 2 ) parachloroamphetamine ( PCA ) , a 5-HT releaser , also enhanced nicotine self-administration in animals in which MAO activity was inhibited ; ( 3 ) pretreatment with tranylcypromine increased PCA-induced 5-HT overflow in the nucleus accumbens . | nicotine ketanserin are the drug combinations. Need more context. |