id
stringlengths 15
19
| document_id
stringlengths 15
19
| passages
list | entities
list | events
list | coreferences
list | relations
list |
|---|---|---|---|---|---|---|
split_0_train_30900 | split_0_train_30900 | [
{
"id": "split_0_train_30900_passage",
"type": "progene_text",
"text": [
"Previous studies showed that sigmaK negatively regulates the level of spoIIID mRNA ."
],
"offsets": [
[
0,
84
]
]
}
] | [
{
"id": "split_0_train_50249_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
29,
35
]
],
"normalized": []
},
{
"id": "split_0_train_50250_entity",
"type": "progene_text",
"text": [
"spoIIID"
],
"offsets": [
[
70,
77
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30901 | split_0_train_30901 | [
{
"id": "split_0_train_30901_passage",
"type": "progene_text",
"text": [
"Here , it is shown that sigmaK does not affect the stability of spoIIID mRNA ."
],
"offsets": [
[
0,
78
]
]
}
] | [
{
"id": "split_0_train_50251_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
24,
30
]
],
"normalized": []
},
{
"id": "split_0_train_50252_entity",
"type": "progene_text",
"text": [
"spoIIID"
],
"offsets": [
[
64,
71
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30902 | split_0_train_30902 | [
{
"id": "split_0_train_30902_passage",
"type": "progene_text",
"text": [
"Rather , sigmaK appears to negatively regulate the synthesis of spoIIID mRNA by accelerating the disappearance of sigmaE RNA polymerase , which transcribes spoIIID ."
],
"offsets": [
[
0,
165
]
]
}
] | [
{
"id": "split_0_train_50253_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
9,
15
]
],
"normalized": []
},
{
"id": "split_0_train_50254_entity",
"type": "progene_text",
"text": [
"spoIIID"
],
"offsets": [
[
64,
71
]
],
"normalized": []
},
{
"id": "split_0_train_50255_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
114,
120
]
],
"normalized": []
},
{
"id": "split_0_train_50256_entity",
"type": "progene_text",
"text": [
"RNA polymerase"
],
"offsets": [
[
121,
135
]
],
"normalized": []
},
{
"id": "split_0_train_50257_entity",
"type": "progene_text",
"text": [
"spoIIID"
],
"offsets": [
[
156,
163
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30903 | split_0_train_30903 | [
{
"id": "split_0_train_30903_passage",
"type": "progene_text",
"text": [
"As sigmaK begins to accumulate by 4 h into sporulation , the sigmaE level drops rapidly in wild - type cells but remains twofold to fivefold higher in sigK mutant cells during the subsequent 4 h ."
],
"offsets": [
[
0,
196
]
]
}
] | [
{
"id": "split_0_train_50258_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
3,
9
]
],
"normalized": []
},
{
"id": "split_0_train_50259_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
61,
67
]
],
"normalized": []
},
{
"id": "split_0_train_50260_entity",
"type": "progene_text",
"text": [
"sigK"
],
"offsets": [
[
151,
155
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30904 | split_0_train_30904 | [
{
"id": "split_0_train_30904_passage",
"type": "progene_text",
"text": [
"In a strain engineered to produce sigmaK 1 h earlier than normal , twofold less sigmaE than that in wild - type cells accumulates ."
],
"offsets": [
[
0,
131
]
]
}
] | [
{
"id": "split_0_train_50261_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
34,
40
]
],
"normalized": []
},
{
"id": "split_0_train_50262_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
80,
86
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30905 | split_0_train_30905 | [
{
"id": "split_0_train_30905_passage",
"type": "progene_text",
"text": [
"SigmaK did not detectably alter the stability of sigmaE in pulse - chase experiments ."
],
"offsets": [
[
0,
86
]
]
}
] | [
{
"id": "split_0_train_50263_entity",
"type": "progene_text",
"text": [
"SigmaK"
],
"offsets": [
[
0,
6
]
],
"normalized": []
},
{
"id": "split_0_train_50264_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
49,
55
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30906 | split_0_train_30906 | [
{
"id": "split_0_train_30906_passage",
"type": "progene_text",
"text": [
"However , beta-galactosidase expression from a sigE - lacZ transcriptional fusion showed a pattern similar to the level of sigmaE protein in sigK mutant cells and cells prematurely expressing sigmaK ."
],
"offsets": [
[
0,
200
]
]
}
] | [
{
"id": "split_0_train_50265_entity",
"type": "progene_text",
"text": [
"beta-galactosidase"
],
"offsets": [
[
10,
28
]
],
"normalized": []
},
{
"id": "split_0_train_50266_entity",
"type": "progene_text",
"text": [
"sigE"
],
"offsets": [
[
47,
51
]
],
"normalized": []
},
{
"id": "split_0_train_50267_entity",
"type": "progene_text",
"text": [
"lacZ"
],
"offsets": [
[
54,
58
]
],
"normalized": []
},
{
"id": "split_0_train_50268_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
123,
129
]
],
"normalized": []
},
{
"id": "split_0_train_50269_entity",
"type": "progene_text",
"text": [
"sigK"
],
"offsets": [
[
141,
145
]
],
"normalized": []
},
{
"id": "split_0_train_50270_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
192,
198
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30907 | split_0_train_30907 | [
{
"id": "split_0_train_30907_passage",
"type": "progene_text",
"text": [
"These results suggest that the appearance of sigmaK initiates a negative feedback loop controlling not only transcription of spoIIID , but the entire sigmaE regulon , by directly or indirectly inhibiting the transcription of sigE ."
],
"offsets": [
[
0,
231
]
]
}
] | [
{
"id": "split_0_train_50271_entity",
"type": "progene_text",
"text": [
"sigmaK"
],
"offsets": [
[
45,
51
]
],
"normalized": []
},
{
"id": "split_0_train_50272_entity",
"type": "progene_text",
"text": [
"spoIIID"
],
"offsets": [
[
125,
132
]
],
"normalized": []
},
{
"id": "split_0_train_50273_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
150,
156
]
],
"normalized": []
},
{
"id": "split_0_train_50274_entity",
"type": "progene_text",
"text": [
"sigE"
],
"offsets": [
[
225,
229
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30908 | split_0_train_30908 | [
{
"id": "split_0_train_30908_passage",
"type": "progene_text",
"text": [
"Complete exon - intron organization of the human gene for the alpha1 chain of type XV collagen ( COL15A1 ) and comparison with the homologous COL18A1 gene ."
],
"offsets": [
[
0,
156
]
]
}
] | [
{
"id": "split_0_train_50275_entity",
"type": "progene_text",
"text": [
"alpha1 chain of type XV collagen"
],
"offsets": [
[
62,
94
]
],
"normalized": []
},
{
"id": "split_0_train_50276_entity",
"type": "progene_text",
"text": [
"COL15A1"
],
"offsets": [
[
97,
104
]
],
"normalized": []
},
{
"id": "split_0_train_50277_entity",
"type": "progene_text",
"text": [
"COL18A1"
],
"offsets": [
[
142,
149
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30909 | split_0_train_30909 | [
{
"id": "split_0_train_30909_passage",
"type": "progene_text",
"text": [
"The human gene for the alpha1 chain of type XV collagen ( COL15A1 ) is about 145 kilobases in size and contains 42 exons ."
],
"offsets": [
[
0,
122
]
]
}
] | [
{
"id": "split_0_train_50278_entity",
"type": "progene_text",
"text": [
"alpha1 chain of type XV collagen"
],
"offsets": [
[
23,
55
]
],
"normalized": []
},
{
"id": "split_0_train_50279_entity",
"type": "progene_text",
"text": [
"COL15A1"
],
"offsets": [
[
58,
65
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30910 | split_0_train_30910 | [
{
"id": "split_0_train_30910_passage",
"type": "progene_text",
"text": [
"The promoter is characterized by the lack of a TATAA motif and the presence of several Sp1 binding sites , some of which appeared to be functional in transfected HeLa cells ."
],
"offsets": [
[
0,
174
]
]
}
] | [
{
"id": "split_0_train_50280_entity",
"type": "progene_text",
"text": [
"Sp1"
],
"offsets": [
[
87,
90
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30911 | split_0_train_30911 | [
{
"id": "split_0_train_30911_passage",
"type": "progene_text",
"text": [
"Comparison with Col18a1 , which encodes the alpha1 ( XVIII ) collagen chain homologous with alpha1 ( XV ) , indicates marked structural homology spread throughout the two genes ."
],
"offsets": [
[
0,
178
]
]
}
] | [
{
"id": "split_0_train_50281_entity",
"type": "progene_text",
"text": [
"Col18a1"
],
"offsets": [
[
16,
23
]
],
"normalized": []
},
{
"id": "split_0_train_50282_entity",
"type": "progene_text",
"text": [
"alpha1 ( XVIII ) collagen chain"
],
"offsets": [
[
44,
75
]
],
"normalized": []
},
{
"id": "split_0_train_50283_entity",
"type": "progene_text",
"text": [
"alpha1 ( XV )"
],
"offsets": [
[
92,
105
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30912 | split_0_train_30912 | [
{
"id": "split_0_train_30912_passage",
"type": "progene_text",
"text": [
"The mouse Col18a1 contains one exon more than COL15A1 , due to the fact that COL15A1 lacks sequences corresponding to exon 3 of Col18a1 , which encodes a cysteine - rich sequence motif ."
],
"offsets": [
[
0,
186
]
]
}
] | [
{
"id": "split_0_train_50284_entity",
"type": "progene_text",
"text": [
"Col18a1"
],
"offsets": [
[
10,
17
]
],
"normalized": []
},
{
"id": "split_0_train_50285_entity",
"type": "progene_text",
"text": [
"COL15A1"
],
"offsets": [
[
46,
53
]
],
"normalized": []
},
{
"id": "split_0_train_50286_entity",
"type": "progene_text",
"text": [
"COL15A1"
],
"offsets": [
[
77,
84
]
],
"normalized": []
},
{
"id": "split_0_train_50287_entity",
"type": "progene_text",
"text": [
"Col18a1"
],
"offsets": [
[
128,
135
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30913 | split_0_train_30913 | [
{
"id": "split_0_train_30913_passage",
"type": "progene_text",
"text": [
"Twenty-five of the exons of the two genes are almost identical in size , six of them contain conserved split codons , and the locations of the respective exon - intron junctions are identical or almost identical in the two genes ."
],
"offsets": [
[
0,
230
]
]
}
] | [] | [] | [] | [] |
split_0_train_30914 | split_0_train_30914 | [
{
"id": "split_0_train_30914_passage",
"type": "progene_text",
"text": [
"The homologous exons include the closely adjacent first pair of exons and the exons encoding a thrombospondin-1 homology found in the N - terminal noncollagenous domain 1 , which are followed by the most variable part of the two genes , covering the C - terminal half of their noncollagenous domain 1 and the beginning of the collagenous portion , after which most of the exons are homologous ."
],
"offsets": [
[
0,
394
]
]
}
] | [
{
"id": "split_0_train_50288_entity",
"type": "progene_text",
"text": [
"thrombospondin-1"
],
"offsets": [
[
95,
111
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30915 | split_0_train_30915 | [
{
"id": "split_0_train_30915_passage",
"type": "progene_text",
"text": [
"The lengths of the introns are not similar in these genes , with two exceptions , namely the first intron , which is very short , less than 100 base pairs , and the second intron , which is very large , about 50 kilobases , in both genes ."
],
"offsets": [
[
0,
239
]
]
}
] | [] | [] | [] | [] |
split_0_train_30916 | split_0_train_30916 | [
{
"id": "split_0_train_30916_passage",
"type": "progene_text",
"text": [
"It can be concluded that COL15A1 and Col18a1 are derived from a common ancestor ."
],
"offsets": [
[
0,
81
]
]
}
] | [
{
"id": "split_0_train_50289_entity",
"type": "progene_text",
"text": [
"COL15A1"
],
"offsets": [
[
25,
32
]
],
"normalized": []
},
{
"id": "split_0_train_50290_entity",
"type": "progene_text",
"text": [
"Col18a1"
],
"offsets": [
[
37,
44
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30917 | split_0_train_30917 | [
{
"id": "split_0_train_30917_passage",
"type": "progene_text",
"text": [
"De novo fatty acid synthesis is required for establishment of cell type - specific gene transcription during sporulation in Bacillus subtilis ."
],
"offsets": [
[
0,
143
]
]
}
] | [] | [] | [] | [] |
split_0_train_30918 | split_0_train_30918 | [
{
"id": "split_0_train_30918_passage",
"type": "progene_text",
"text": [
"A hallmark of sporulation of Bacillus subtilis is the formation of two distinct cells by an asymmetric septum ."
],
"offsets": [
[
0,
111
]
]
}
] | [] | [] | [] | [] |
split_0_train_30919 | split_0_train_30919 | [
{
"id": "split_0_train_30919_passage",
"type": "progene_text",
"text": [
"The developmental programme of these two cells involves the compartmentalized activities of sigmaE in the larger mother cell and of sigmaF in the smaller prespore ."
],
"offsets": [
[
0,
164
]
]
}
] | [
{
"id": "split_0_train_50291_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
92,
98
]
],
"normalized": []
},
{
"id": "split_0_train_50292_entity",
"type": "progene_text",
"text": [
"sigmaF"
],
"offsets": [
[
132,
138
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30920 | split_0_train_30920 | [
{
"id": "split_0_train_30920_passage",
"type": "progene_text",
"text": [
"A potential role of de novo lipid synthesis on development was investigated by treating B. subtilis cells with cerulenin , a specific inhibitor of fatty acid biosynthesis ."
],
"offsets": [
[
0,
172
]
]
}
] | [] | [] | [] | [] |
split_0_train_30921 | split_0_train_30921 | [
{
"id": "split_0_train_30921_passage",
"type": "progene_text",
"text": [
"These experiments demonstrated that spore formation requires de novo fatty acid synthesis at the onset of sporulation ."
],
"offsets": [
[
0,
119
]
]
}
] | [] | [] | [] | [] |
split_0_train_30922 | split_0_train_30922 | [
{
"id": "split_0_train_30922_passage",
"type": "progene_text",
"text": [
"The transcription of the sporulation genes that are induced before the formation of two cell types or that are under the exclusive control of sigmaF occurred in the absence of fatty acid synthesis , as monitored by spo - lacZ fusions ."
],
"offsets": [
[
0,
235
]
]
}
] | [
{
"id": "split_0_train_50293_entity",
"type": "progene_text",
"text": [
"sigmaF"
],
"offsets": [
[
142,
148
]
],
"normalized": []
},
{
"id": "split_0_train_50294_entity",
"type": "progene_text",
"text": [
"spo"
],
"offsets": [
[
215,
218
]
],
"normalized": []
},
{
"id": "split_0_train_50295_entity",
"type": "progene_text",
"text": [
"lacZ"
],
"offsets": [
[
221,
225
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30923 | split_0_train_30923 | [
{
"id": "split_0_train_30923_passage",
"type": "progene_text",
"text": [
"However , expression of lacZ fusions to genes that required activation of sigmaE for transcription was inhibited in the absence of fatty acid synthesis ."
],
"offsets": [
[
0,
153
]
]
}
] | [
{
"id": "split_0_train_50296_entity",
"type": "progene_text",
"text": [
"lacZ"
],
"offsets": [
[
24,
28
]
],
"normalized": []
},
{
"id": "split_0_train_50297_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
74,
80
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30924 | split_0_train_30924 | [
{
"id": "split_0_train_30924_passage",
"type": "progene_text",
"text": [
"The block in sigmaE - directed gene expression in cerulenin - treated cells was caused by an inability to process pro - sigmaE to its active form ."
],
"offsets": [
[
0,
147
]
]
}
] | [
{
"id": "split_0_train_50298_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
13,
19
]
],
"normalized": []
},
{
"id": "split_0_train_50299_entity",
"type": "progene_text",
"text": [
"sigmaE"
],
"offsets": [
[
120,
126
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30925 | split_0_train_30925 | [
{
"id": "split_0_train_30925_passage",
"type": "progene_text",
"text": [
"Electron microscopy revealed that these fatty acid - starved cells initiate abnormal polar septation , suggesting that de novo fatty acid synthesis may be essential to couple the activation of the mother cell transcription factors with the formation of the differentiating cells ."
],
"offsets": [
[
0,
280
]
]
}
] | [
{
"id": "split_0_train_50300_entity",
"type": "progene_text",
"text": [
"transcription factors"
],
"offsets": [
[
209,
230
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30926 | split_0_train_30926 | [
{
"id": "split_0_train_30926_passage",
"type": "progene_text",
"text": [
"The first gene of the Bacillus subtilis clpC operon , ctsR , encodes a negative regulator of its own operon and other class III heat shock genes ."
],
"offsets": [
[
0,
146
]
]
}
] | [
{
"id": "split_0_train_50301_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
40,
44
]
],
"normalized": []
},
{
"id": "split_0_train_50302_entity",
"type": "progene_text",
"text": [
"ctsR"
],
"offsets": [
[
54,
58
]
],
"normalized": []
},
{
"id": "split_0_train_50303_entity",
"type": "progene_text",
"text": [
"class III heat shock genes"
],
"offsets": [
[
118,
144
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30927 | split_0_train_30927 | [
{
"id": "split_0_train_30927_passage",
"type": "progene_text",
"text": [
"The Bacillus subtilis clpC operon is regulated by two stress induction pathways relying on either sigmaB or a class III stress induction mechanism acting at a sigmaA - like promoter ."
],
"offsets": [
[
0,
183
]
]
}
] | [
{
"id": "split_0_train_50304_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
22,
26
]
],
"normalized": []
},
{
"id": "split_0_train_50305_entity",
"type": "progene_text",
"text": [
"sigmaB"
],
"offsets": [
[
98,
104
]
],
"normalized": []
},
{
"id": "split_0_train_50306_entity",
"type": "progene_text",
"text": [
"sigmaA"
],
"offsets": [
[
159,
165
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30928 | split_0_train_30928 | [
{
"id": "split_0_train_30928_passage",
"type": "progene_text",
"text": [
"When the clpC operon was placed under the control of the isopropyl-beta-D-thiogalactopyranoside ( IPTG ) - inducible Pspac promoter , dramatic repression of the natural clpC promoters fused to a lacZ reporter gene was noticed after IPTG induction ."
],
"offsets": [
[
0,
248
]
]
}
] | [
{
"id": "split_0_train_50307_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
9,
13
]
],
"normalized": []
},
{
"id": "split_0_train_50308_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
169,
173
]
],
"normalized": []
},
{
"id": "split_0_train_50309_entity",
"type": "progene_text",
"text": [
"lacZ"
],
"offsets": [
[
195,
199
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30929 | split_0_train_30929 | [
{
"id": "split_0_train_30929_passage",
"type": "progene_text",
"text": [
"This result strongly indicated negative regulation of the clpC operon by one of its gene products ."
],
"offsets": [
[
0,
99
]
]
}
] | [
{
"id": "split_0_train_50310_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
58,
62
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30930 | split_0_train_30930 | [
{
"id": "split_0_train_30930_passage",
"type": "progene_text",
"text": [
"Indeed , the negative regulator could be identified which is encoded by the first gene of the clpC operon , ctsR , containing a predicted helix - turn - helix DNA - binding motif ."
],
"offsets": [
[
0,
180
]
]
}
] | [
{
"id": "split_0_train_50311_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
94,
98
]
],
"normalized": []
},
{
"id": "split_0_train_50312_entity",
"type": "progene_text",
"text": [
"ctsR"
],
"offsets": [
[
108,
112
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30931 | split_0_train_30931 | [
{
"id": "split_0_train_30931_passage",
"type": "progene_text",
"text": [
"Deletion of ctsR abolished the negative regulation and resulted in high expression of both the clpC operon and the clpP gene under nonstressed conditions ."
],
"offsets": [
[
0,
155
]
]
}
] | [
{
"id": "split_0_train_50313_entity",
"type": "progene_text",
"text": [
"ctsR"
],
"offsets": [
[
12,
16
]
],
"normalized": []
},
{
"id": "split_0_train_50314_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
95,
99
]
],
"normalized": []
},
{
"id": "split_0_train_50315_entity",
"type": "progene_text",
"text": [
"clpP"
],
"offsets": [
[
115,
119
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30932 | split_0_train_30932 | [
{
"id": "split_0_train_30932_passage",
"type": "progene_text",
"text": [
"Nevertheless , a further increase in clpC and clpP mRNA levels was observed after heat shock , even in the absence of sigmaB , suggesting a second induction mechanism at the vegetative promoter ."
],
"offsets": [
[
0,
195
]
]
}
] | [
{
"id": "split_0_train_50316_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
37,
41
]
],
"normalized": []
},
{
"id": "split_0_train_50317_entity",
"type": "progene_text",
"text": [
"clpP"
],
"offsets": [
[
46,
50
]
],
"normalized": []
},
{
"id": "split_0_train_50318_entity",
"type": "progene_text",
"text": [
"sigmaB"
],
"offsets": [
[
118,
124
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30933 | split_0_train_30933 | [
{
"id": "split_0_train_30933_passage",
"type": "progene_text",
"text": [
"Two - dimensional gel analysis and mRNA studies showed that the expression of other class III stress genes was at least partially influenced by the ctsR deletion ."
],
"offsets": [
[
0,
163
]
]
}
] | [
{
"id": "split_0_train_50319_entity",
"type": "progene_text",
"text": [
"ctsR"
],
"offsets": [
[
148,
152
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30934 | split_0_train_30934 | [
{
"id": "split_0_train_30934_passage",
"type": "progene_text",
"text": [
"Studies with different clpC promoter fragments either fused to the reporter gene bgaB or used in gel mobility shift experiments with the purified CtsR protein revealed a possible target region where the repressor seemed to bind in vivo and in vitro ."
],
"offsets": [
[
0,
250
]
]
}
] | [
{
"id": "split_0_train_50320_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
23,
27
]
],
"normalized": []
},
{
"id": "split_0_train_50321_entity",
"type": "progene_text",
"text": [
"bgaB"
],
"offsets": [
[
81,
85
]
],
"normalized": []
},
{
"id": "split_0_train_50322_entity",
"type": "progene_text",
"text": [
"CtsR"
],
"offsets": [
[
146,
150
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30935 | split_0_train_30935 | [
{
"id": "split_0_train_30935_passage",
"type": "progene_text",
"text": [
"Our data demonstrate that the CtsR protein acts as a global repressor of the clpC operon , as well as other class III heat shock genes , by preventing unstressed transcription from either the sigmaB - or sigmaA - dependent promoter and might be inactivated or dissociate under inducing stress conditions ."
],
"offsets": [
[
0,
305
]
]
}
] | [
{
"id": "split_0_train_50323_entity",
"type": "progene_text",
"text": [
"CtsR"
],
"offsets": [
[
30,
34
]
],
"normalized": []
},
{
"id": "split_0_train_50324_entity",
"type": "progene_text",
"text": [
"clpC"
],
"offsets": [
[
77,
81
]
],
"normalized": []
},
{
"id": "split_0_train_50325_entity",
"type": "progene_text",
"text": [
"sigmaB"
],
"offsets": [
[
192,
198
]
],
"normalized": []
},
{
"id": "split_0_train_50326_entity",
"type": "progene_text",
"text": [
"sigmaA"
],
"offsets": [
[
204,
210
]
],
"normalized": []
}
] | [] | [] | [] |
split_0_train_30936 | split_0_train_30936 | [
{
"id": "split_0_train_30936_passage",
"type": "progene_text",
"text": [
""
],
"offsets": [
[
0,
0
]
]
}
] | [] | [] | [] | [] |