dedup-isc-ft-v107-score
float64 0.3
1
| uid
stringlengths 32
32
| text
stringlengths 1
17.9k
| paper_id
stringlengths 8
11
| original_image_filename
stringlengths 7
69
|
|---|---|---|---|---|
0.407397 | db5506c472b442fd8232d31d7f9783e8 | Chromatogram of HPLC compounds identified from BSM. | PMC9947098 | gr3.jpg |
0.459623 | fddc5a24024448f88383e520de9f4855 | Percentage survival of D. melanogaster treated with S. mombin stem bark fractions. #[P < 0.05]; significant compared with 1 mL ethanol/10 g diet. | PMC9947098 | gr4.jpg |
0.405984 | 48817f8c99e846da85283accf5d64295 | Locomotor (climbing) activity of diabetes and normal D. melanogaster treated with ESM and BSM. ∗[P < 0.05] significant compared to the normal control (Group 1). | PMC9947098 | gr5.jpg |
0.382126 | d1d674c743014e688f4b405b8fb01e96 | (a) NO level (b) Lipid peroxidation level (c) Total thiol level and (d) glucose concentration of diabetic and normal D. melanogaster treated with ESM and BSM. ∗[P < 0.05] significant compared to the normal control (Group 1); #[P < 0.05] significant compared with Group 2; &[P < 0.05] significant compared with Group 3. | PMC9947098 | gr6.jpg |
0.438086 | d93c42d54a73460c92cdc8ed297adad2 | (a) ILP-2, (b) InR and (c) IMPL-2 mRNA expression of diabetes and normal D. melanogaster treated with ESM and BSM a[P < 0.05] significant compared with Group 1; b[P < 0.05] significant compared with Group 4. | PMC9947098 | gr7.jpg |
0.425572 | 375a30ee5b0444f1a2f0404c02e3dd40 | The binding conformation of co-crystallized (green) and redocked (blue) ligands at the catalytic site of α-amylase (2QV4) | PMC9947098 | gr8.jpg |
0.479755 | b766510c3d024cd99fa6465a27fdf15f | Two-dimensional presentation of interactions of compounds with catalytic pocket of α-amylase (2QV4). | PMC9947098 | gr9.jpg |
0.44497 | 781362dcdedb4233bb5d881ab25806ce | Trial pathway. POBIG is a phase I dose/volume escalation trial that is testing the safety and feasibility of providing a single fraction of preoperative radiotherapy in patients with a new radiological diagnosis of glioblastoma. Our trial pathway has been developed in collaboration with local and national patient focus groups. Abbreviations: MDT = multidisciplinary team; preop = preoperative; RT = radiotherapy. | PMC9947330 | gr1.jpg |
0.426182 | 4010dbd470f6424293e9db5ba4d3f90e | Example of a POBIG preoperative radiotherapy treatment plan. A unique aspect of this trial is that part of the tumour is excluded from the radiation field for diagnostic sampling (cold spot). The area that is deemed highest risk of residual disease is given the full dose of radiation (hot spot). The preoperative radiotherapy dose delivered to the hot spot will vary from 6 to 14 Gy. | PMC9947330 | gr2.jpg |
0.451984 | 2608e0466d8b44b2a349dca6e5480c5d | Treatment levels in the Continual Reassessment Method (CRM) model. Cohorts will be opened dependent on radiotherapy dose and irradiated volume. We will firstly progress down treatment levels in the <30 cm3 category before opening larger radiotherapy treatment volume categories. | PMC9947330 | gr3.jpg |
0.488778 | ab7455a48179458da61d069c257b230c | PRISMA 2020 flow diagram for the systematic review about the searches of databases, registers, and other sources (Page et al., 2021). | PMC9947632 | S2054425122000619_fig1.jpg |
0.509665 | 975349f12fa44856998f3b5b7a8a898a | Flow of participants through the study | PMC9948461 | 12891_2022_6108_Fig1_HTML.jpg |
0.470434 | 5ca23390d8354aaab0fe29298d4008bc | Pain intensity scores and disability level for all groups across time. Notes: PE indicates patient education, and MCE indicates motor control exercise | PMC9948461 | 12891_2022_6108_Fig2_HTML.jpg |
0.47489 | a33792ebfeb344768f58e2525184b3c1 | Physical health and mental health scores for all groups across time. Notes: PE indicates patient education, and MCE indicates motor control exercise | PMC9948461 | 12891_2022_6108_Fig3_HTML.jpg |
0.436285 | f27c356d9a514db79016a678094853e9 | Global perceived recovery scores for all groups across time. Notes: PE indicates patient education, and MCE indicates motor control exercise | PMC9948461 | 12891_2022_6108_Fig4_HTML.jpg |
0.465271 | db65be33c2584247b0cf612c1d8ae0b0 | Fear-avoidance beliefs about physical activity and work scores for all groups across time. Notes: PE indicates patient education, and MCE indicates motor control exercise | PMC9948461 | 12891_2022_6108_Fig5_HTML.jpg |
0.47483 | 1191740f89ff402288fd5422818eeb45 | Pain catastrophising and back pain consequences belief scores for all groups across time. Notes: PE indicates patient education, and MCE indicates motor control exercise | PMC9948461 | 12891_2022_6108_Fig6_HTML.jpg |
0.475628 | c7f96de020cd43aea5c77ed9006141a2 | Flowchart of the X-ray based setup workflow performed for each patient with the couch at 0°. | PMC9948862 | gr1.jpg |
0.461558 | 26a731cfe9f845139ad5b148e36a3167 | Flowchart of the simulated AC (a) and NC (b) scenarios for the treatment couch positioned at couch angle k. | PMC9948862 | gr2.jpg |
0.449948 | 274b036264e0481992a8487d3cfa054b | Residual translational (a) and rotational (b) misalignment at the stage of patient setup as reported by ET XV. XSC refers to the 6 DoF from the acquisition performed after manual prepositioning based on treatment room lasers, whereas XSV indicates the residual misalignment reported from the acquisition following treatment couch correction. The boxes span from the 25th percentile to the 75th percentile thus displaying the IQR. Their lower and upper whiskers indicate the range between the 2.5th percentile and 97.5th percentile. Values outside this 95% CI are considered outliers. | PMC9948862 | gr3.jpg |
0.452086 | d12643e133f647f79ddd92af5700208f | Translational (a) and rotational (b) misalignment at non-coplanar treatment couch angles as reported by ET XV for the AC and NC scenario. The boxes span from the 25th percentile to the 75th percentile thus displaying the IQR. Their lower and upper whiskers indicate the range between the 2.5th percentile and 97.5th percentile. Values outside this 95% CI are considered outliers. Data from the 34 acquisitions followed by a couch correction are not included in the boxplot of the AC scenario, to avoid bias in the distribution due to multiple zeros. | PMC9948862 | gr4.jpg |
0.478193 | f3cbf3214bfb49b48fd5d588f119d64f | Correlation for 651 DSCs with geometrical properties such as PTV volume (a) and offset from the treatment isocenter (b) as well as with translational (c) and rotational patient misalignment (d) calculated for 130 PTVs. Panel (e) features 620 DSCs for 123 PTVs smaller than 4 cm3 scattered against combined 6 DoF patient misalignment. The associated isocentric offset is color-coded, whereas the PTV volume is represented by the marker size. | PMC9948862 | gr5.jpg |
0.39927 | 83b4cdc2e21748bd831db76e603cdc5e | Scatterplot of ΔD98% against the corresponding DoF in pure translational (a), pure rotational (b), and combined misalignments (c). The five individual PTVs are color-coded. | PMC9948862 | gr6.jpg |
0.430006 | 2015afc867524b3884caa6738b44e5f4 | Relative DVH parameters for 75 PTVs (a), 75 GTVs (b) and CCR for both groups (c) at dose recalculation under AC and NC scenario. Positive CCR values reflect a loss of prescription isodose coverage in the given scenario compared to the treatment plan. The boxes span from the 25th percentile to the 75th percentile thus displaying the IQR. Their lower and upper whiskers indicate the range between the 2.5th percentile and 97.5th percentile. Values outside this 95% CI are considered outliers. | PMC9948862 | gr7.jpg |
0.417962 | 5e3c2430bd2d4ea881ac8decbfbda1fc | Relationship of CCR with geometrical PTV properties such as the absolute volume VPTV or the offset from the treatment isocenter diso for both AC and NC scenarios. The respective property is categorized in three groups and color-coded. | PMC9948862 | gr8.jpg |
0.423178 | 789dc443291d47358a1be20e5f13ede3 | Study design. aOptional visit. However, administration of study intervention and entry of patient diary should continue. bAssessments will be performed only for patients providing consent/assent to participate in the exploratory period. Op = optional, V = visit. | PMC9949372 | medi-102-e33024-g001.jpg |
0.425958 | 82f8372c81a9426a9a04326c14de6142 | Kaplan–Meier plot of the time to resolution of the 5 COVID-19 symptoms in the patient group with <72 h from the onset to randomization in the phase 2b study (ITT* population). *This population comprises all patients randomly assigned to the study intervention with SARS-CoV-2 viral titer detected at baseline. The detection of SARS-CoV-2 viral titer was confirmed by viral titer assessment based on nasopharyngeal swab samples. Patients were analyzed according to the assigned study intervention. COVID-19 = coronavirus disease 2019, ITT = intention-to-treat, SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2. | PMC9949372 | medi-102-e33024-g002.jpg |
0.435839 | 7164a881f1f04168b03a7aae4421af5a | Schedule of activities. | PMC9949372 | medi-102-e33024-g003.jpg |
0.427696 | c9bef7b186bc435b8e0e3565ebd8d245 | Weibull distribution (A) and corresponding hazard ratio curve (B) assumed when calculating the required number of patients for the phase 3 study for the time to resolution of the 5 symptoms of COVID-19. COVID-19 = coronavirus disease 2019. | PMC9949372 | medi-102-e33024-g004.jpg |
0.490759 | 6b6edab190e64f149e29a727cdb42d6d | Proportion of patients showing occurrence of smell disorder (A) and taste disorder (B) in the phase 2b study (ITT* population). *This population comprises all patients randomly assigned to the study intervention with SARS-CoV-2 viral titer detected at baseline. The detection of SARS-CoV-2 viral titer will be confirmed by viral titer assessment based on nasopharyngeal swab sample. Patients will be analyzed according to the assigned study intervention. ITT = intention-to-treat, SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2. | PMC9949372 | medi-102-e33024-g005.jpg |
0.439266 | af0ce596204b4f25976e57384f5447ab | (A) A 3-dimensional model of the bilateral femur and (B, C) axial computed
tomography images of the hip and posterior femoral condyle in a 26-year-old
man with absolute femoral retroversion. (B) The femoral head center (white
dot) was connected with the center of the femoral shaft on the level of the
lesser trochanter to define the proximal landmarks. (C) The posterior
condyles were connected with a line for the distal landmarks. | PMC9950619 | 10.1177_23259671221148502-fig1.jpg |
0.443519 | 91efbba004e54ea1a5b535ad56e2ea9b | Determining the location of acetabular (top row) and femoral (bottom row)
hip impingement during the FADIR test at 90° of flexion and 30° of
internal rotation combined with (A) 0°, (B) 10°, and (C) 20° of
adduction on computed tomography scans from a 23-year-old man with
absolute femoral retroversion. The impingement area is outlined in red.
FADIR, flexion, adduction, internal rotation. | PMC9950619 | 10.1177_23259671221148502-fig2.jpg |
0.419668 | 533f0135ca4d4fe5be27fb681d296f7e | Frequency of extra-articular subspine hip impingement for patients with
absolute femoral retroversion during the FADIR test: 90° of flexion; 30° of
internal rotation (IR); and 0°, 10°, or 20° of adduction. FADIR, flexion,
adduction, internal rotation. | PMC9950619 | 10.1177_23259671221148502-fig3.jpg |
0.429724 | 8bf38ae6a19c4eea8cd508a58cfce2c7 | A clockface system was used for intra-articular impingement location, where 1
to 2 o’clock represents anterosuperior, 4 to 5 o’clock represents
anteroinferior, and 3 o’clock anterior (for left and right hips). The
anterior femoral impingement location was significantly different at maximal
flexion (anteroinferior; 4-5 o’clock) vs during the FADIR test
(anterosuperior and anterior; 2-3 o’clock) (P < .001).
FADIR, flexion, adduction, internal rotation. | PMC9950619 | 10.1177_23259671221148502-fig4.jpg |
0.408555 | 3516759d7c2248f7bda2d609361b4f30 | Age Differences in Bed and Rise Times.Note: y = years; pre = pre-lockdown; peri = peri-lockdown; SOL = sleep onset latency; SPT = sleep period time (A) Results of the first questionnaire comparing the pre-covid situation with the first lockdown. (B) Results of the second questionnaire comparing the pre-covid situation with the second lockdown. | PMC9951628 | pb-63-1-1160-g1.jpg |
0.402662 | eb63c1fed3024bb0b7a53094f188890e | Prevalence of Clinical Insomnia.Note: (A) Pre-lockdown prevalences from the first questionnaire. (B) Peri-lockdown prevalences from the first questionnaire. (C) Pre-lockdown prevalences from the second questionnaire. (D) Peri-lockdown prevalences from the second questionnaire. | PMC9951628 | pb-63-1-1160-g2.jpg |
0.509484 | 44c9dfa04fe64caf9f14ab98c5566132 | Insomnia Severity Index Scores.Note: (A) Results of the first questionnaire comparing the pre-covid situation with the first lockdown. (B) Results of the second questionnaire comparing the pre-covid situation with the second lockdown. | PMC9951628 | pb-63-1-1160-g3.jpg |
0.488248 | 6f159dfe7ed04eef9babadb4e6b58fc7 | Effect of the Pandemic on Bedtime, Sleep Onset Latency and Rise Time.Note: SOL = sleep onset latency; SPT = sleep period time A) Results of the first questionnaire comparing the pre-covid situation with the first lockdown. (B) Results of the second questionnaire comparing the pre-covid situation with the second lockdown. | PMC9951628 | pb-63-1-1160-g4.jpg |
0.428905 | 0a4b3720e4984f1098091e18fcc8edd6 | Effect of the Pandemic on Total Sleeping Time, Time in Bed and Sleep Efficiency.Note: (A) Results of the first questionnaire comparing the pre-covid situation with the first lockdown. (B) Results of the second questionnaire comparing the pre-covid situation with the second lockdown. | PMC9951628 | pb-63-1-1160-g5.jpg |
0.350294 | 2cf16943616a44c7a22d98b55ee4d0e1 | Box-and-whisker plot showing the median values for the mercury concentrations of the organs tested in common woodpigeons of both genders. Box shows 25–75% coefficient, whiskers show minimum and maximum range of non-outliers. | PMC9951639 | animals-13-00575-g001.jpg |
0.369551 | 2a1060be9d38418aaecad3f9a818f75b | Box-and-whisker plot showing the median values for the mercury concentrations of the organs tested in Eurasian magpies of both genders. Box shows 25–75% coefficient, whiskers show minimum and maximum range of non-outliers. | PMC9951639 | animals-13-00575-g002.jpg |
0.526071 | 1952c70d013b4161b8ffeeff955a4568 | The mean ± SEM of (a) the essential metal index (EMI) and (b) the non-essential metal index (NEMI) in the ovarian tissues of free-ranging queens of different groups. | PMC9951721 | animals-13-00650-g001.jpg |
0.546616 | 2e5a102fa4a644baa7f0639ff7e06fb1 | The mean ± SEM of (a) the essential metal index (EMI) and of (b) the non-essential metal index (NEMI) in ovarian tissues of free ranging bitches of different groups. | PMC9951721 | animals-13-00650-g002.jpg |
0.436263 | 0fb9654cdd8c4f0ea95dcab20fd350b3 | LPS treatment dynamically regulates IPMK expression levels in macrophages. (A–G) Macrophages were stimulated with LPS (100 ng/mL) for the indicated times. Levels of IPMK protein (red triangle) were analyzed by immunoblotting lysates of (A) RAW 264.7 cells and (B) BMDMs. Quantification of IPMK protein levels obtained from at least three independent experiments. Densitometric data were normalized to GAPDH control for (C) RAW 264.7 cells (n = 4) and (D) BMDMs (n = 3). Bars represent means ± SE. (E–G) mRNA levels of Ipmk were quantified by RT-qPCR in (E) RAW 264.7 cells, (F) BMDMs, and (G) THP-1 cells. Bars represent means ± SE (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 (one-way ANOVA followed by Tukey’s post hoc test (C–G)). | PMC9952907 | biomolecules-13-00332-g001.jpg |
0.447256 | 243f7574faae4757a410b10593030a24 | 33-bp deletion of IPMK 3′UTR attenuates the TLR4 signaling response by LPS. (A) Schematic representation of the reporter plasmid psiCheck2 IPMK 3′UTR. (B) Predicted miR-181c binding site in the IPMK 3′UTR. Perfect matches are indicated by vertical lines; G:U pairs by colons. Red letters represent point mutations introduced to disrupt miRNA binding. (C,D) Relative luciferase activities were measured in HEK293T cells 24 h after co-transfection with a luciferase reporter plasmid and miR-181c mimic (C). Levels of endogenous IPMK protein were analyzed by immunoblotting the same lysates (D,E) Ipmk mRNA expression levels in RAW 264.7 cells were measured by RT-qPCR. (F) Schematic diagram showing the IPMK 3’UTR deletion of the putative miR-181c binding site which is highlighted in blue. The seed sequence is labeled in bold. (G) Levels of Ipmk mRNA expression were measured by RT-qPCR in 264.7WT and 264.7Δ3′UTR cells after LPS (100 ng/mL) treatment for 2 h. Data shown are representative of three independent experiments and are presented as means ± SE (n = 3). ** p < 0.01, *** p < 0.001, ns; not significant (two-way ANOVA followed by Tukey’s post hoc test (C,G), Student’s t test (E)). | PMC9952907 | biomolecules-13-00332-g002.jpg |
0.429106 | b1a034ff907a47a7bb15285815c82cb4 | 264.7Δ3′UTR cells exhibit downregulated TLR4-dependent inflammatory responses. (A) Phosphorylation of TLR4 downstream signaling molecules was analyzed by immunoblotting lysates of 264.7WT or 264.7Δ3′UTR cells stimulated for 2 h or 6 h with 100 ng/mL of LPS. The red triangle indicates the target band. (B–D) mRNA levels of proinflammatory cytokines Il-1β (B), Il-6 (C) and, TNF-α (D) were measured by RT-qPCR in 264.7WT or 264.7Δ3′UTR cells 0, 2, or 6 h after stimulation with 100 ng/mL of LPS. (E,F) Secreted levels of the IL-6 (E) and TNF-α (F) in culture medium were measured by multiplex immunoassay after stimulation with LPS (100 ng/mL). Data shown are representative of at least three independent experiments and are presented as means ± SE. * p < 0.05, ** p < 0.01, *** p < 0.001 (Mann-Whitney test (n = 6, B–D), two-way ANOVA followed by Tukey’s post hoc test (n = 3, E,F)). | PMC9952907 | biomolecules-13-00332-g003.jpg |
0.409467 | bc973de24f6d4275a3d5ad0620416075 | K63-linked ubiquitination of TRAF6 was decreased in IPMK Δ3’UTR macrophages. (A) Levels of endogenous TRAF6 K63 ubiquitination were measured in either 264.7WT or 264.7Δ3′UTR cells in the absence or presence of LPS (100 ng/mL) treatment for 1 h. Cell lysates were subject to immunoprecipitation with anti-TRAF6 antibodies, followed by immunoblot analysis with anti-K63 ubiquitin-specific antibodies. (B) Model depicting the regulation of TLR4 signaling by IPMK. In LPS-stimulated macrophages, Ipmk mRNA and protein levels were decreased, thus allowing the full transmission of TLR4-triggered signaling and inflammatory gene expression. When this acute downregulation of IPMK is not properly working by the deletion of Ipmk 3′UTR, K63-linked ubiquitination of TRAF6 becomes lowered, which impairs the activation of TLR4 signaling and inflammatory response. | PMC9952907 | biomolecules-13-00332-g004.jpg |
0.430943 | 64799dbff5b34f49b9967234b86e1f6e | Temporal trend in published papers on N. norvegicus showing a sharp increase after 1989 onward. The last year (2022) is not finalized, so the total number of published papers is still incomplete (i.e., runs until the 15 August). | PMC9953252 | biology-12-00225-g001.jpg |
0.423401 | 7a310f710b7e4914968c122c943b9ce6 | The term clustering map based on the analysis of publications concerned with N. norvegicus retrieved from SCOPUS database from the period 1965–2022. Red, blue, and green colors represent the terms belonging to different clusters. The dot size of each term is based on the number of its occurrence. The connecting lines indicate the 300 strongest co-occurrence links between terms. | PMC9953252 | biology-12-00225-g002.jpg |
0.420095 | 2dfd73339ff34bb7aa3ec50c74373330 | The citation map, indicating the frequency of term citation (i.e., the hotness of topics) within the surveyed bibliography. | PMC9953252 | biology-12-00225-g003.jpg |
0.417851 | 1587c4e5fdfc48f49e7fc82f4a3ed82f | Term year map analysis results, depicting the global temporal trend in the development of research topics. | PMC9953252 | biology-12-00225-g004.jpg |
0.45918 | f02bba8ecfa44209b5eb8f81a7dc1dab | Laser therapy devices and sensors used in the present study to investigate laser beam parameters: (a) EMS laser; (b) K-laser; (c) thermal power sensor; (d) photodiode; (e) experimental setup to measure temporal profiles showing the diffusor in between the photodiode and the handpiece of the EMS laser as well as the oscilloscope (MSO7024) that recorded signals from the photodiode; (f) beam profiling camera. Modified from [7] with permission from the authors. Details are in the text. | PMC9953381 | biomedicines-11-00585-g001.jpg |
0.484016 | 87006531c162476d9c7af317fc8f76a9 | Power measurements of the three EMS lasers (EMS-1, blue dots and blue lines; EMS-2, orange dots and orange lines; EMS-3, green dots and green lines): (a) measured power (Pm) for eight different powers set at the EMS laser units (Pset); (b) the difference between Pm and Pset at each set power; (c) deviation of Pm compared to Pset as a percentage. Black dashed lines illustrate ideal curves where Pm equals Pset. | PMC9953381 | biomedicines-11-00585-g002.jpg |
0.418456 | fd650edeb04a4458a4506a45b6adab6d | Temporal and spatial characteristics of the three EMS lasers (EMS-1, EMS-2 and EMS-3): (a–c) pulse recordings of each EMS laser recorded at different repetition rates. EMS-1 was measured at three repetition rates while EMS-2 and EMS-3 were also measured at 10 kHz and 30 kHz; (d–f) color-coded spatial intensity distributions of the three EMS lasers. Magenta represents the lowest light intensity, and red represents the highest light intensity. White lines that are projected onto the grid planes are intensity profiles along center lines in the x- and y-directions. | PMC9953381 | biomedicines-11-00585-g003.jpg |
0.438515 | e9b1c748246d4069a5709f2a182372fd | Power measurements of the three K-lasers (K-1, blue dots and blue lines; K-2, orange dots and orange lines; K-3, green dots and green lines) used as continuous wave (CW) lasers. Measured power (Pm) for different powers set at the devices (Pset). (a–c) Measurements using the three wavelengths (800 nm, 905 nm, 970 nm) individually; (d) measurements using all diodes simultaneously. Black dashed lines illustrate ideal curves where Pm equals Pset. | PMC9953381 | biomedicines-11-00585-g004.jpg |
0.438602 | 59ec2529e49447b9837ebc794e571090 | Difference between set powers (Pset) and measured powers (Pm) of the three K-lasers (K1, (a–e); K-2, (f–j); K-3, (k–o)) operated in pulsed wave (PW) mode at varying repetition rates. The lasers were measured using each wavelength individually: (a,f,k), 800 nm; (b,g,l), 905 nm; (c,h,m), 970 nm; they were also measured using all diodes simultaneously: (d,i,n), all diodes. In addition, they were measured in intense super pulse (ISP) mode, which is also using all diodes but in a different pulsing mode: (e,j,o), ISP. Dashed horizontal lines at zero in each diagram illustrate ideal curves where Pm equals Pset. | PMC9953381 | biomedicines-11-00585-g005.jpg |
0.502403 | 179045e5afd9426480fc922b54387c0c | Relative deviation of measured power compared to set power as a percentage for the three K-lasers (K-1, (a–e); K-2, (f–j); K-3, (k–o)) operated in pulsed wave mode at varying repetition rates. Values were computed from measured power values that are shown in Figure 5. Dashed horizontal lines at zero in each diagram illustrate ideal curves. | PMC9953381 | biomedicines-11-00585-g006.jpg |
0.484404 | 8c49a23f29f749e8adc95705ae9b15ab | Light intensity in time for K-1 in the pulsed wave (PW) mode at different repetition rates: (a) 1 Hz; (b) 10 Hz; (c) 100 Hz; (d) 1 kHz; (e) 10 kHz; (f) 20 kHz. Pulses were recorded using the three diodes (800 nm, 905 nm, 970 nm) individually, all diodes simultaneously and using the K-lasers’ intense super pulse (ISP) mode. All measurements were done with K-1 set to maximum average power. The signals were normalized to the maximum value of each repetition rate. | PMC9953381 | biomedicines-11-00585-g007.jpg |
0.423988 | 26d0f54141ce4e2a86ca42d04d9246a8 | Color-coded light intensity distributions of the three K-lasers: for each unit, the three diodes (800 nm, 905 nm, 970 nm) were recorded individually as well as all diodes simultaneously and the K-lasers’ intense-super pulse (ISP) mode. Magenta represents the lowest light intensity, and red represents the highest light intensity. Projections of beam profiles along the horizontal and vertical axes are shown as white lines behind the intensity distributions. Recordings were taken with the K-lasers’ zoom objective set to sizes 1 and 3. The intensities of each recording were maximized by adjusting the camera exposure time. | PMC9953381 | biomedicines-11-00585-g008.jpg |
0.498546 | 5168f0c58fb447b495d6d9aec71a4868 | Beam profiles for the three K-lasers along a horizontal line across the intensity distributions: (a–e) K-1; (f–j) K-2; (k–o) K-3. The profiles were extracted from camera recordings of the individual diodes (800 nm, 905 nm, 970 nm), all diodes simultaneously and the K-lasers’ intense-super-pulse (ISP) mode. The sizes 1–5 were set at the zoom objective of each device. For K-2, four modes (800 nm, 905 nm, 970 nm, all diodes) were only recorded for sizes 1 and 3. All signals were normalized to their maximum intensity. | PMC9953381 | biomedicines-11-00585-g009.jpg |
0.4682 | 4c0e2c7c85bb4078a03e1dec6cc8f505 | Flow diagram of the study population selection process. | PMC9953812 | cancers-15-01265-g001.jpg |
0.404646 | e2132d09134549408dc73e4e2323af2d | PFS of studied population. | PMC9953812 | cancers-15-01265-g002.jpg |
0.442209 | 1c02a22ae622459fadad4edb60b57eff | OS of studied population. | PMC9953812 | cancers-15-01265-g003.jpg |
0.421211 | 08aa2c8795dd4f85a4e8cbff5cbee4dc | Relationship between OS and presence of liver metastases in the study population. | PMC9953812 | cancers-15-01265-g004.jpg |
0.455827 | 4fee6ba37a4d495fbb3ab9d896666776 | Relationship between OS and NLR value in the study population. | PMC9953812 | cancers-15-01265-g005.jpg |
0.44231 | 1fcc5e33d0ae4deb8115bf25129d9079 | Age group distribution of LAI and OAP groups. | PMC9953951 | brainsci-13-00173-g001.jpg |
0.464899 | d1797421ae72410498b5e6eea021b91a | Concomitant treatment in LAI versus OAP groups. | PMC9953951 | brainsci-13-00173-g002.jpg |
0.413996 | 56e526c08dd34713a92c3b2081a113c2 | Work-flow diagram leading to the sandwich immunoassay for E. coli detection with SERS-tags. (Schematic depiction—parts not to scale.) The numbers in parentheses refer to the article sections dealing with methodology (2.x) and results (3.x) of the individual steps. The synthesis of AuNRs is followed by their characterization with electron microscopy. Reporter molecules are then attached to the AuNRs and their SERS signal is analyzed. Subsequent antibody attachment provides a complete SERS-tag. Au-coated glass is derivatized with antibodies and the immobilization of bacteria is tested. In the final step, the branches of the diagram unite to afford the sandwich immunoassay, and its analytical performance is tested with multiple bacterial species. | PMC9954015 | biosensors-13-00182-g001.jpg |
0.428809 | f9d73fd5e8b84a6ca6d341a928d4fca2 | SEM image of the synthesized AuNRs placed on a thin carbon film. Taken at 30 kV, 50 pA with transmission detector in (A): Bright Field, (B): High Angle Annular Dark Field mode. Instrument: Helios G4 (Courtesy of Thermo Fisher Scientific). Average dimensions: (≈ 90%): 40 ± 4 nm × 24 ± 2 nm, (≈ 10%): 42 ± 4 nm × 8 ± 2 nm. Measurement parameters cf. 2.7. | PMC9954015 | biosensors-13-00182-g002.jpg |
0.584794 | 5bbbcd5d759649cea030f90a26955f2b | (A): Characteristic spectral response from AuNR-based SERS of adsorbed DTNB, applied in concentration 0.1 mM, compared to Raman spectroscopy of pure solid DTNB (2.52 M). Average spectra from 6 measurements each for SERS and RS. Absolute values of the spectral response were measured at identical laser power and integration time. (B): Characteristic spectral response from AuNR based SERS of adsorbed DTNB, applied in concentration 0.1 mM, compared to Raman spectroscopy of a thin layer of DTNB on CaF2, from 100 mM solution, cf. Section 3.1. Average spectra from 6 measurements (SERS) and 15 measurements (RS). Microscope objective: 20×; for measurement parameters, see Section 2.8. | PMC9954015 | biosensors-13-00182-g003.jpg |
0.439768 | 8e0440018d9f44f483dd1acc1de0d308 | Bright-field microscope images of Au-coated glass derivatized with E. coli-specific antibody and treated with suspensions containing E. coli; >1700 cells/FOV (A), S. aureus; ≈ 400 cells/FOV (B) and S. marcescens; ≈ 100 cells/FOV (C). The applied suspensions had equivalent bacterial concentrations in the order 1 × 105 CFU/mL. The Au-coated glass was washed several times with PBS before observation, cf. Section 2.6. Microscope objective: 20×; scale bars: 20 µm. | PMC9954015 | biosensors-13-00182-g004.jpg |
0.466192 | 779d7bff9dc14cfb9902943921be93bf | Sandwich immunoassay SERS signal intensity and specificity. (A): Average SERS spectra from individual cells of different bacterial species (see legend), in the E. coli-specific sandwich complex. E. coli cells were covered with the SERS-tags and detected by the strong SERS signal of DTNB. In case of S. marcescens and S. aureus, the signal is weaker, indicating relatively low level of undesirable non-specific interactions between these bacteria and the SERS-tags. The nominal SERS signal intensities are presented in the bar graph below. The shaded areas represent the 95% confidence interval. Microscope objective: 50×. (B): Average SERS signal intensity maxima at 1329 cm−1, from the bacteria subjected to sandwich immunoassay, i.e., immobilization on the gold-plated glass covered in antibodies and to the detection process involving SERS-tags. The positive, specific signal of E. coli is more than 3.5× stronger than the non-specific signal of the S. marcescens and over 28× stronger than that of S. aureus. The numbers in red show the calculated amounts of the individual SERS-tags per bacterium. The error bars represent the 95% confidence interval of ISERS. | PMC9954015 | biosensors-13-00182-g005.jpg |
0.467514 | 1bd470ad15804b06a9535559836bb427 | (A) Fabrication of difunctional fluorescent hydrogel fiber. (B) Optical setup for simultaneous continuous pH and glucose monitoring. | PMC9954304 | biosensors-13-00287-g001.jpg |
0.405708 | 06b9efae0ae0445984c5610a1f9cc9fc | The photographs of the fluorescent hydrogel fiber. (A) The optical microscope photograph of the hydrogel fiber. Scale bar = 0.5 mm. (B) The fluorescence photograph of fluorescent hydrogel fiber excited with 490 nm light. (C,D) Fluorescence photographs of hydrogel fiber underside UV light (365 nm) illumination. (E) Photographs of the fabricated hydrogel fibers. | PMC9954304 | biosensors-13-00287-g002.jpg |
0.372503 | 2a1ab9d680e543c885e312fc40778375 | (A) TEM image and size distribution of CdTe QDs. (B) FT-IR. Top to bottom: blank hydrogel, amino hydrogel, fluorescein derivative functionalized hydrogel, and 3−APBA functionalized hydrogel. (C) Emission spectra of fluorescein derivative and QDs. Insets: fluorescence photographs of fluorescein derivative and QDs under UV light (365 nm) illumination. (D) Absorption spectra of fluorescein derivative and QDs. Insets: solution under white light. (E) The propagation loss of hydrogel fibers in the air with/without cladding, measured by a cutback technique. The wavelength of the light was 532 nm. (F) Absorption spectra of blank hydrogel and difunctional hydrogel. Dual emission was acquired from the spectrometer of the monitoring system. | PMC9954304 | biosensors-13-00287-g003.jpg |
0.501956 | 12d2f1bce19a4a0a8681e83fd09d4ff2 | (A) Time response of pH detection from pH 3.4 to pH 9.0. The dots represent the fluorescence intensity recorded every 10 s, which is the same as (B,C). The moments when pH starts to change are pointed out with arrows, which is the same as (C). (B) Repeatability of the sensor for pH detection from pH 5.4 to pH 7.4. The green dashed lines represent reference fluorescence intensity corresponding to pH 7.4 (up) and pH 5.4 (down). (C) Time response of the sensor for continuous pH monitoring (pH 7.0→6.2→5.4→6.2→7→7.8→6.2→7.4→7.0). The green dashed lines represent reference fluorescence intensity corresponding to pH 6.2 (down) and pH 7.0 (up). (D) Detection curve of the sensor for pH. Inset: linear relation of fluorescence intensity to pH. Error bars in (B–D) are based on standard deviations (n = 3). | PMC9954304 | biosensors-13-00287-g004.jpg |
0.516394 | ce70ee736dbf440e8152d8bb3e3fab30 | (A) Schematic diagram of volume change of the hydrogel and the fluorescence change caused by glucose concentration changes. (B) Time response of the sensor for going through three consecutive glucose additions, buffering, and sensor resetting cycles. The dots represent the fluorescence intensity recorded every 2 min. (C) Time response of the sensor for continuous glucose monitoring. The dots represent the fluorescence intensity recorded every 8 min. The moments when pH start to change are pointed out with arrows. (D) Linear detection for glucose of the sensor. (E) Percentage of fluorescence intensity decline; a–h: blank hydrogel, glucose, lactate (0.75 mM), fructose (8.1 μM), K+, Na+, Mg2+, Ca2+. Error bars in (B–E) are based on standard deviations (n = 3). | PMC9954304 | biosensors-13-00287-g005.jpg |
0.445311 | e21471117b494aa2881fa5b4e87ea494 | (A) Time response of fluorescence intensity at 517 nm and 594 nm when pH changed in the range of 6.6–7.8 with a fixed glucose concentration of 10 mM. The dots represent the fluorescence intensity recorded every 4 min, which is the same as (B,C). The moments when pH and glucose concentration start to change are pointed out with arrows, which are the same as (B,C). The solid line is for ease of understanding. (B) Time response of fluorescence intensity at 517 nm and 594 nm when glucose concentration changed in the range of 1–10 mM with fixed pH at 7.4. (C) Time response of fluorescence intensity at 517 nm and 594 for cross changes of pH and glucose concentration. The cyan vertical dashed lines play the same role as the arrows. (D) Deviation of glucose detection in (C). The blue dashed line indicates that the detected glucose concentration equals the actual glucose concentration. All error bars are based on standard deviations (n = 3). | PMC9954304 | biosensors-13-00287-g006.jpg |
0.456381 | 07ce712ea15e4a8c9f6baf705ef2974b | The equilibrium between phenylboronic acid and the conjugate phenylboronate in aqueous media. | PMC9954304 | biosensors-13-00287-sch001.jpg |
0.438629 | a8ff1c5b61974bb8b92579c9b6e4bada | Circulating biomarkers of HCC. Shown are two types of circulating biomarkers (blood and urine, a focus of this review), the proposed strategies to reduce the cost of testing, and their potential applications in LRS for HCC screening, diagnosis, and management. | PMC9954913 | diagnostics-13-00676-g001.jpg |
0.495883 | 799d14531a0b4c95a51b951b3d9b0383 | Kaplan–Meier estimate of freedom from aortic dissection. Note the statistically significantly increased rate of events in the positive carriers. | PMC9956195 | genes-14-00252-g001.jpg |
0.475473 | 6b1bbf15aa024d209153ceb9edcaa2f9 | Freedom from dissection or death in the KIF6 719Arg carriers and non-carriers. Note the small but statistically significantly increased rate of events in the positive carriers. | PMC9956195 | genes-14-00252-g0A1.jpg |
0.43379 | 961d7536812c44879819fedf3cbbe032 | Discriminant diagram. | PMC9956209 | foods-12-00718-g001.jpg |
0.393367 | 45014545f5ca4bbf8c2e39acabc0d2a1 | TBARS values in raw and cooked samples (ppm of MDA). BOV, bovine steak; BUR, hamburger; SAL, salmon fillet; POR, pork steak. Different letters within sample kinds correspond to different values for p < 0.05. | PMC9956209 | foods-12-00718-g002.jpg |
0.467207 | bfea0c47208346d9a86b0036b4f25d5f | Workflow of the study design employed to ask multiple research questions related to SORCS3′s association with brain-related disorders and traits. | PMC9956385 | genes-14-00482-g001.jpg |
0.497754 | 9849d28b48394537b03b6c987f149d78 | Plot of the SORCS3 gene. The LD relationship between the 46 SNPs is displayed in measures of r2 (red, below the diagonal) and D’ (blue, above the diagonal). SNPs are mapped to their position along the gene and to their tag groups, which are high-LD blocks containing multiple associated SNPs. Three SNPs are not in LD with other SNPs (rs10786832 (tag SNP #4), rs2930456 (tag SNP #6) and rs12359689 (tag SNP #8)). rs1855581 at the 5′ end of the gene is not an associated SNP and is just present to extend the map to include exon 1 and, thus, display all exons of the gene. | PMC9956385 | genes-14-00482-g002.jpg |
0.440791 | bd06f6d134a0421ba9ecca6811df5281 | Heritability enrichment analysis of the SORCS3 gene-set stratified linkage disequilibrium score regression (sLDSC). Test (top) and control (bottom) phenotypes are plotted on the y-axis. Enrichment values (proportion of h2/proportion of # SNPs), where an enrichment score of 1 indicates no enrichment, are plotted on the x-axis, with error bars representing standard error and p-values displayed. Phenotypes where the p-value remains significant after Bonferroni correction are shown in red. Full results of the sLDSC analysis are located in Supplementary Table S3. | PMC9956385 | genes-14-00482-g003.jpg |
0.443615 | 2ddbeebf4ed94b7a920c7f763d79b754 | SynGO enrichment of the SORCS3 gene-set. The central circle in the sunburst plot includes all SynGO annotated genes, which then subdivides based on the hierarchy of annotation terms. The dashed line runs through the SynGO terms that contain SORCS3. (A) Five Cellular Component terms are significantly enriched at 1% FDR (testing terms with at least three matching input genes), and these terms are in the postsynapse. (B) Fifteen Biological Processes terms are significantly enriched, and these terms are in synapse organisation (blue terms), postsynaptic processes (orange terms) and synaptic signalling (red terms). | PMC9956385 | genes-14-00482-g004a.jpg |
0.463312 | da659e2fe6274e1bbb7836fedb83945f | Ulcers with well-defined edges and surrounding erythema, covered by fibrin on the lower leg. | PMC9957114 | 1678-9849-rsbmt-56-e0465-2022-gf1.jpg |
0.4255 | 0ac0ab55294341bf889332c4f5e6d76f | Clean ulcers over indurated plaques after antibiotic therapy on the lower limb. | PMC9957114 | 1678-9849-rsbmt-56-e0465-2022-gf2.jpg |
0.400536 | 9fa27a57e52245a780abc8cb496bb2c2 | Inclusion flowchart. Notes. a See AgeWell.de study protocol for more detailed information on the inclusion criteria [22]. | PMC9957242 | ijerph-20-02975-g001.jpg |
0.447877 | 274e13d7baf5484fba227215013042e7 | Experimental equipment. | PMC9957250 | ijerph-20-02839-g001.jpg |
0.371385 | c61e7ee3fd244e9c9e1c18fcb607377b | Soil detachment rate by sediment-laden rill flow under different levels of sediment load. | PMC9957250 | ijerph-20-02839-g002.jpg |
0.495741 | 05b9f8b0b1b140e5aeb2571c09f5cae1 | Measured vs. predicted detachment rates using the soil detachment equation in WEPP for 294 trials. | PMC9957250 | ijerph-20-02839-g003.jpg |
0.414778 | bbf431d6d90840dcbf6f260ca4ab9775 | Measured vs. predicted detachment rates using the soil detachment equation in EUROSEM for 294 trials. | PMC9957250 | ijerph-20-02839-g004.jpg |
0.481396 | d03e6f7be8674d5eb2bee43de6e5d27a | Measured vs. predicted detachment rates using the revised EUROSEM soil detachment equation without vs for 294 trials. | PMC9957250 | ijerph-20-02839-g005.jpg |
0.393337 | 06350b2cebd846089abdbe84ab530d39 | Brief-COPE subscales distribution in the whole sample. Avoidant coping subscales are colored in red, active coping subscales in green, and neither active nor avoidant coping subscales in yellow, respectively. The frequencies for each coping strategy are reported on the right side of each bar as percentages. | PMC9957361 | ijerph-20-02974-g001.jpg |
0.391249 | 8573045204de4f3da3d8d2aa4319c592 | Logistic regression of anxiety and depressive symptoms as predicted by coping styles. Two models are presented for anxiety and depressive symptoms indexed as having reached the GAD−7 and PHQ−9 cut-off values, respectively. Avoidant coping subscales are plotted in red, active coping subscales in green, and neither active nor avoidant in yellow. The odds ratio (OR) indicates the effect size and is reported with 95% confidence intervals (CI). The reference line of odds ratio (OR = 1) is cranberry colored. | PMC9957361 | ijerph-20-02974-g002.jpg |
0.415969 | f4b4c647d88e457180a1ddb09eb14aae | Location of the study region. | PMC9957405 | ijerph-20-02844-g001.jpg |
0.437179 | 47369ef111e04538ae923927486189ad | Research framework. | PMC9957405 | ijerph-20-02844-g002.jpg |