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Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
information
Q63-S4-A1
134
Tay-Sachs disease is a life-threatening disease of the nervous system passed down through families.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
information
Q63-S4-A2
135
Summary Tay-Sachs disease is a rare, inherited disorder. It causes too much of a fatty substance to build up in the brain. This buildup destroys nerve cells, causing mental and physical problems. Infants with Tay-Sachs disease appear to develop normally for the first few months of life. Then mental and physical abilities decline. The child becomes blind, deaf, and unable to swallow. Muscles begin to waste away and paralysis sets in. Even with the best of care, children with Tay-Sachs disease usually die by age 4. The cause is a gene mutation which is most common in Eastern European Ashkenazi Jews. To get the disease, both parents must have the gene. If they do, there is a 25% chance of the child having the disease. A blood test and prenatal tests can check for the gene or the disease. There is no cure. Medicines and good nutrition can help some symptoms. Some children need feeding tubes. NIH: National Institute of Neurological Disorders and Stroke
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
information
Q63-S4-A3
136
Tay-Sachs disease is a rare inherited disorder that causes progressive destruction of nerve cells in the brain and spinal cord. Tay-Sachs is caused by the absence of a vital enzyme called hexosaminidase-A (Hex-A). Without Hex-A, a fatty substance, or lipid, called GM2 ganglioside accumulates abnormally in cells, especially in the nerve cells of the brain. This ongoing accumulation causes progressive damage to the cells. Tay-Sachs disease is inherited in an autosomal recessive pattern.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
information
Q63-S4-A4
137
Tay-Sachs disease is a rare inherited disorder that progressively destroys nerve cells (neurons) in the brain and spinal cord. The most common form of Tay-Sachs disease becomes apparent in infancy. Infants with this disorder typically appear normal until the age of 3 to 6 months, when their development slows and muscles used for movement weaken. Affected infants lose motor skills such as turning over, sitting, and crawling. They also develop an exaggerated startle reaction to loud noises. As the disease progresses, children with Tay-Sachs disease experience seizures, vision and hearing loss, intellectual disability, and paralysis. An eye abnormality called a cherry-red spot, which can be identified with an eye examination, is characteristic of this disorder. Children with this severe infantile form of Tay-Sachs disease usually live only into early childhood. Other forms of Tay-Sachs disease are very rare. Signs and symptoms can appear in childhood, adolescence, or adulthood and are usually milder than those seen with the infantile form. Characteristic features include muscle weakness, loss of muscle coordination (ataxia) and other problems with movement, speech problems, and mental illness. These signs and symptoms vary widely among people with late-onset forms of Tay-Sachs disease.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
cause
Q63-S5-A1
138
Tay-Sachs disease occurs when the body lacks hexosaminidase A. This is a protein that helps break down a group of chemicals found in nerve tissue called gangliosides. Without this protein, gangliosides, particularly ganglioside GM2, build up in cells, especially nerve cells in the brain. Tay-Sachs disease is caused by a defective gene on chromosome 15. When both parents carry the defective Tay-Sachs gene, a child has a 25% chance of developing the disease. The child must receive two copies of the defective gene, one from each parent, in order to become sick. If only one parent passes the defective gene to the child, the child is called a carrier. They will not be sick, but may pass the disease to their own children. Anyone can be a carrier of Tay-Sachs. But, the disease is most common among the Ashkenazi Jewish population. 1 in every 27 members of the population carries the Tay-Sachs gene. Tay-Sachs is divided into infantile, juvenile, and adult forms, depending on the symptoms and when they first appear. Most people with Tay-Sachs have the infantile form. In this form, the nerve damage usually begins while the baby is still in the womb. Symptoms usually appear when the child is 3 to 6 months old. The disease tends to get worse very quickly, and the child usually dies by age 4 or 5. Late-onset Tay-Sachs disease, which affects adults, is very rare.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
prevention
Q63-S6-A1
139
There is no known way to prevent this disorder. Genetic testing can detect if you are a carrier of the gene for this disorder. If you or your partner are from an at-risk population, it is recommended that you undergo testing before starting a family. Testing the amniotic fluid can diagnose Tay-Sachs disease in the womb.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
treatment
Q63-S7-A1
140
There is no treatment for Tay-Sachs disease itself, only ways to make the person more comfortable.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
treatment
Q63-S7-A2
141
Although several attempts have been made at purified enzyme replacement therapy for children with Tay-Sachs disease, none has been successful. Cellular infusions and even bone marrow transplantation have been attempted with no evidence of benefit. Because no specific treatment is available for Tay-Sachs disease, treatment is directed at the symptoms and major associated conditions. Treatment is supportive and aimed at providing adequate nutrition and hydration. The airway must be protected. Seizures can be controlled initially with conventional anticonvulsant medications such as benzodiazepines, phenytoins, and/or barbiturates, but the progressive nature of the disease may require alteration of dosage or medication. Infectious diseases should be managed. In advanced disease, good bowel movement should be maintained and severe constipation should be avoided. Good hydration, food additives, stool softeners, laxatives, and other measures should be employed to avoid severe constipation.
Q63
list of questions
I have a list of questions about Tay sachs disease and clubfoot 1. what is TSD/Clubfoot, and how does it effect a baby 2. what causes both? can it be prevented, treated, or cured 3. How common is TSD? how common is Clubfoot 4. How can your "agency" help a women/couple who are concerned about this congenital condition, and is there a cost? If you can answer these few questions I would be thankful, please get back as soon as you can.
tsd
treatment
Q63-S7-A3
142
These resources address the diagnosis or management of Tay-Sachs disease: - Gene Review: Gene Review: Hexosaminidase A Deficiency - Genetic Testing Registry: Tay-Sachs disease - MedlinePlus Encyclopedia: Tay-Sachs Disease These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
Q64
null
Hello, I have a scoliosis problem plz help me I want its treatment I can send my x.ray also *** This message has been sent using QMobile A2 Classic ***
scoliosis
treatment
Q64-S1-A1
143
Treatment depends on many things: - The cause of scoliosis - Where the curve is in your spine - How big the curve is - If your body is still growing Most people with idiopathic scoliosis do not need treatment. But you should still be checked by a doctor about every 6 months. If you are still growing, your doctor might recommend a back brace. A back brace prevents further curving. There are many different types of braces. What kind you get depends on the size and location of your curve. Your provider will pick the best one for you and show you how to use it. Back braces can be adjusted as you grow. Back braces work best in people over age 10. Braces do not work for those with congenital or neuromuscular scoliosis. You may need surgery if the spine curve is severe or getting worse very quickly. Surgery involves correcting the curve as much as possible: - Surgery is done with a cut through the back, belly area, or beneath the ribs. - The spine bones are held in place with 1 or 2 metal rods. The rods are held down with hooks and screws until the bone heals together. - After surgery, you may need to wear a brace for a while to keep the spine still. Scoliosis treatment may also include: - Emotional support: Some children, especially teens, may be self-conscious when using a back brace. - Physical therapy and other specialists to help explain the treatments and make sure the brace fits correctly.
Q65
EAR LOBE CREASES
Are ear lobe creases always heart disease and 100% heart attack pending? What are other causes? I'm 56 have pierced ears but haven't wore earrings in years. In the last 7 years I rarely eat meat and when I do it's chicken or fish maybe beef every 5 years or so and its maybe a hamburger lean. If you do have arteriosclerosis is there anyway to reverse it?
heart attack
cause
Q65-S1-A1
144
A substance called plaque can build up in the walls of your coronary arteries. This plaque is made up of cholesterol and other cells. A heart attack may occur when: - A tear in the plaque occurs. This triggers blood platelets and other substances to form a blood a clot at the site that blocks most or all of the oxygen-carrying blood from flowing to a part of the heart muscle. This is the most common cause of heart attack. - A slow buildup of plaque may narrow one of the coronary arteries so that it is almost blocked. In either case, there is not enough blood flow to the heart muscle and heart muscle dies. The cause of heart attack is not always known. Heart attack may occur: - When you are resting or asleep - After a sudden increase in physical activity - When you are active outside in cold weather - After sudden, severe emotional or physical stress, including an illness Many risk factors may lead to the development of plaque buildup and a heart attack.
Q65
EAR LOBE CREASES
Are ear lobe creases always heart disease and 100% heart attack pending? What are other causes? I'm 56 have pierced ears but haven't wore earrings in years. In the last 7 years I rarely eat meat and when I do it's chicken or fish maybe beef every 5 years or so and its maybe a hamburger lean. If you do have arteriosclerosis is there anyway to reverse it?
heart attack
cause
Q65-S1-A2
145
Coronary Heart Disease A heart attack happens if the flow of oxygen-rich blood to a section of heart muscle suddenly becomes blocked and the heart can't get oxygen. Most heart attacks occur as a result of coronary heart disease (CHD). CHD is a condition in which a waxy substance called plaque builds up inside of the coronary arteries. These arteries supply oxygen-rich blood to your heart. When plaque builds up in the arteries, the condition is called atherosclerosis. The buildup of plaque occurs over many years. Eventually, an area of plaque can rupture (break open) inside of an artery. This causes a blood clot to form on the plaque's surface. If the clot becomes large enough, it can mostly or completely block blood flow through a coronary artery. If the blockage isn't treated quickly, the portion of heart muscle fed by the artery begins to die. Healthy heart tissue is replaced with scar tissue. This heart damage may not be obvious, or it may cause severe or long-lasting problems. Coronary Artery Spasm A less common cause of heart attack is a severe spasm (tightening) of a coronary artery. The spasm cuts off blood flow through the artery. Spasms can occur in coronary arteries that aren't affected by atherosclerosis. What causes a coronary artery to spasm isn't always clear. A spasm may be related to: Taking certain drugs, such as cocaine Emotional stress or pain Exposure to extreme cold Cigarette smoking The animation below shows how plaque buildup or a coronary artery spasm can lead to a heart attack. Click the "start" button to play the animation. Written and spoken explanations are provided with each frame. Use the buttons in the lower right corner to pause, restart, or replay the animation, or use the scroll bar below the buttons to move through the frames. The animation shows how blocked blood flow in a coronary artery can lead to a heart attack.  
Q65
EAR LOBE CREASES
Are ear lobe creases always heart disease and 100% heart attack pending? What are other causes? I'm 56 have pierced ears but haven't wore earrings in years. In the last 7 years I rarely eat meat and when I do it's chicken or fish maybe beef every 5 years or so and its maybe a hamburger lean. If you do have arteriosclerosis is there anyway to reverse it?
heart attack
cause
Q65-S1-A3
146
Most heart attacks are caused by a blood clot that blocks one of the coronary arteries, the blood vessels that bring blood and oxygen to the heart muscle. When blood cannot reach part of your heart, that area starves for oxygen. If the blockage continues long enough, cells in the affected area die. The Most Common Cause Coronary heart disease (CHD)is the most common underlying cause of a heart attack. CHD, also called coronary artery disease, is the hardening and narrowing of the coronary arteries caused by the buildup of plaque inside the walls of the arteries. When plaque builds up in the arteries, the condition is called atherosclerosis (ath-er-o-skler-O-sis). The buildup of plaque occurs over many years. Over time, an area of plaque can rupture (break open) inside of an artery. This causes a blood clot to form on the plaque's surface. If the clot becomes large enough, it can mostly or completely block blood flow through a coronary artery. If the blockage isn't treated quickly, the portion of heart muscle fed by the artery begins to die. Healthy heart tissue is replaced with scar tissue. This heart damage may not be obvious, or it may cause severe or long-lasting problems. Other Causes Heart attack also can occur due to problems with the very small, microscopic blood vessels of the heart. This condition is called microvascular disease. It's believed to be more common in women than in men. A less common cause of heart attacks is a severe spasm or tightening of the coronary artery that cuts off blood flow to the heart. These spasms can occur in persons with or without coronary artery disease. What causes a coronary artery to spasm isn't always clear. A spasm may be related to emotional stress or pain, exposure to extreme cold, cigarette smoking, or by taking certain drugs like cocaine. Risk Factors You Cannot Change Certain factors make it more likely that you will develop coronary artery disease and have a heart attack. These risk factors include some things you cannot change. If you are a man over age 45 or a woman over age 55, you are at greater risk. Having a family history of early heart disease, diagnosed in a father or brother before age 55 or in a mother or sister before age 65, is another risk factor. You are also at risk if you have a personal history of angina or previous heart attack, or if you have had a heart procedure such as percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG). Risk Factors You Can Change Importantly, there are many risk factors that you can change. These include - smoking - being overweight or obese - physical inactivity - high blood pressure - high blood cholesterol - high blood sugar due to insulin resistance or diabetes - an unhealthy diet (for example, a diet high in saturated fat, trans fat, cholesterol, and sodium). smoking being overweight or obese physical inactivity high blood pressure high blood cholesterol high blood sugar due to insulin resistance or diabetes an unhealthy diet (for example, a diet high in saturated fat, trans fat, cholesterol, and sodium). Metabolic Syndrome Some of these risk factors—such as obesity, high blood pressure, and high blood sugar—tend to occur together. When they do, it's called metabolic syndrome. In general, a person with metabolic syndrome is twice as likely to develop heart disease and five times as likely to develop diabetes as someone without metabolic syndrome.
Q65
EAR LOBE CREASES
Are ear lobe creases always heart disease and 100% heart attack pending? What are other causes? I'm 56 have pierced ears but haven't wore earrings in years. In the last 7 years I rarely eat meat and when I do it's chicken or fish maybe beef every 5 years or so and its maybe a hamburger lean. If you do have arteriosclerosis is there anyway to reverse it?
arteriosclerosis
treatment
Q65-S2-A1
147
Treatments for atherosclerosis may include heart-healthy lifestyle changes, medicines, and medical procedures or surgery. The goals of treatment include: Lowering the risk of blood clots forming Preventing atherosclerosis-related diseases Reducing risk factors in an effort to slow or stop the buildup of plaque Relieving symptoms Widening or bypassing plaque-clogged arteries Heart-Healthy Lifestyle Changes Your doctor may recommend heart-healthy lifestyle changes if you have atherosclerosis. Heart-healthy lifestyle changes include heart-healthy eating, aiming for a healthy weight, managing stress, physical activity and quitting smoking. Medicines Sometimes lifestyle changes alone aren’t enough to control your cholesterol levels. For example, you also may need statin medications to control or lower your cholesterol. By lowering your blood cholesterol level, you can decrease your chance of having a heart attack or stroke. Doctors usually prescribe statins for people who have: Coronary heart disease, peripheral artery disease, or had a prior stroke Diabetes High LDL cholesterol levels Doctors may discuss beginning statin treatment with people who have an elevated risk for developing heart disease or having a stroke. Your doctor also may prescribe other medications to: Lower your blood pressure Lower your blood sugar levels Prevent blood clots, which can lead to heart attack and stroke Prevent inflammation Take all medicines regularly, as your doctor prescribes. Don’t change the amount of your medicine or skip a dose unless your doctor tells you to. You should still follow a heart healthy lifestyle, even if you take medicines to treat your atherosclerosis. Medical Procedures and Surgery If you have severe atherosclerosis, your doctor may recommend a medical procedure or surgery. Percutaneous coronary intervention (PCI), also known as coronary angioplasty, is a procedure that’s used to open blocked or narrowed coronary (heart) arteries. PCI can improve blood flow to the heart and relieve chest pain. Sometimes a small mesh tube called a stent is placed in the artery to keep it open after the procedure. Coronary artery bypass grafting (CABG) is a type of surgery. In CABG, arteries or veins from other areas in your body are used to bypass or go around your narrowed coronary arteries. CABG can improve blood flow to your heart, relieve chest pain, and possibly prevent a heart attack. Bypass grafting also can be used for leg arteries. For this surgery, a healthy blood vessel is used to bypass a narrowed or blocked artery in one of the legs. The healthy blood vessel redirects blood around the blocked artery, improving blood flow to the leg. Carotid endarterectomy is a type of surgery to remove plaque buildup from the carotid arteries in the neck. This procedure restores blood flow to the brain, which can help prevent a stroke.
Q66
Cervical Cancer
Can a long term untreated bladder infection aid in the cause of cervical cancer? And can the fact that my mom has cervical cancer aid in my chance of getting cervical cancer?
cervical cancer
cause
Q66-S1-A1
148
Worldwide, cervical cancer is the third most common type of cancer in women. It is much less common in the United States because of the routine use of Pap smears. Cervical cancer starts in the cells on the surface of the cervix. There are two types of cells on the surface of the cervix, squamous and columnar. Most cervical cancers are from squamous cells. Cervical cancer usually develops slowly. It starts as a precancerous condition called dysplasia. This condition can be detected by a Pap smear and is 100% treatable. It can take years for dysplasia to develop into cervical cancer. Most women who are diagnosed with cervical cancer today have not had regular Pap smears, or they have not followed up on abnormal Pap smear results. Almost all cervical cancers are caused by HPV (human papillomavirus). HPV is a common virus that is spread through sexual intercourse. There are many different types (strains) of HPV. Some strains lead to cervical cancer. Other strains can cause genital warts. Others do not cause any problems at all. A woman's sexual habits and patterns can increase her risk of developing cervical cancer. Risky sexual practices include: - Having sex at an early age - Having multiple sexual partners - Having a partner or many partners who take part in high-risk sexual activities Other risk factors for cervical cancer include: - Not getting the HPV vaccine - Being economically disadvantaged - Having a mother who took the drug diethylstilbestrol (DES) during pregnancy in the early 1960s to prevent miscarriage - Having a weakened immune system
Q67
father suffering from IBS
My father is suffering from IBS and is loosing weight day by day.sometimes he even faints due to weakness.He cannot digest food .please help us and suggest us upon this problem.
ibs
treatment
Q67-S1-A1
149
The goal of treatment is to relieve symptoms. In some cases of IBS, lifestyle changes can help. For example, regular exercise and improved sleep habits may reduce anxiety and help relieve bowel symptoms. Dietary changes can be helpful. However, no specific diet can be recommended for IBS because the condition differs from one person to another. The following changes may help: - Avoiding foods and drinks that stimulate the intestines (such as caffeine, tea, or colas) - Eating smaller meals - Increasing fiber in the diet (this may improve constipation or diarrhea, but make bloating worse) Talk with your provider before taking over-the-counter medicines. No one medicine works for everyone. Some that your provider may suggest include: - Anticholinergic medicines (dicyclomine, propantheline, belladonna, and hyoscyamine) taken about a half-hour before eating to control intestinal muscle spasms - Bisacodyl to treat constipation - Loperamide to treat diarrhea - Low doses of tricyclic antidepressants to help relieve intestinal pain - Lubiprostone for constipation symptoms - Rifaximin, an antibiotic Psychological therapy or medicines for anxiety or depression may help with the problem.
Q68
null
Lewy Body Disease. I have been researching Lewy Body Disease and have a few questions.1) Is this disease hereditary2) Does alcoholism play a role in the beginning process of this disease3) What are the initial symptoms of the diseaseAny information you could forward would be greatly appreciated.
lewy body disease
inheritance
Q68-S1-A1
150
Most cases of Lewy body dementia are not thought to be inherited. The condition generally occurs sporadically in people with no family history of the condition. Rarely, the condition can affect more than one family member. Some of these cases appear to be due to single gene changes (mutations) that follow an autosomal dominant pattern of inheritance. Other familial cases do not follow a specific pattern of inheritance and likely have a multifactorial cause (associated with the effects of multiple genes in combination with lifestyle and environmental factors).
Q68
null
Lewy Body Disease. I have been researching Lewy Body Disease and have a few questions.1) Is this disease hereditary2) Does alcoholism play a role in the beginning process of this disease3) What are the initial symptoms of the diseaseAny information you could forward would be greatly appreciated.
lewy body disease
cause
Q68-S2-A1
151
Lewy body dementia is characterized by the abnormal buildup of proteins into masses known as Lewy bodies. This protein is also associated with Parkinson's disease. People who have Lewy bodies in their brains also have the plaques and tangles associated with Alzheimer's disease.
Q68
null
Lewy Body Disease. I have been researching Lewy Body Disease and have a few questions.1) Is this disease hereditary2) Does alcoholism play a role in the beginning process of this disease3) What are the initial symptoms of the diseaseAny information you could forward would be greatly appreciated.
lewy body disease
symptom
Q68-S3-A1
152
The Human Phenotype Ontology provides the following list of signs and symptoms for Lewy body dementia. If the information is available, the table below includes how often the symptom is seen in people with this condition. You can use the MedlinePlus Medical Dictionary to look up the definitions for these medical terms. Signs and Symptoms Approximate number of patients (when available) Abnormality of extrapyramidal motor function 90% Abnormality of the autonomic nervous system 90% Developmental regression 90% EEG abnormality 90% Hallucinations 90% Hypertonia 90% Hypotension 90% Sleep disturbance 90% Sudden cardiac death 90% Gait disturbance 50% Incoordination 50% Neurological speech impairment 50% Abnormality of the sense of smell 7.5% Feeding difficulties in infancy 7.5% Involuntary movements 7.5% Restrictive lung disease 7.5% Skin ulcer 7.5% Tremor 7.5% Autosomal dominant inheritance - Delusions - Dementia - Fluctuations in consciousness - Parkinsonism - Visual hallucinations - The Human Phenotype Ontology (HPO) has collected information on how often a sign or symptom occurs in a condition. Much of this information comes from Orphanet, a European rare disease database. The frequency of a sign or symptom is usually listed as a rough estimate of the percentage of patients who have that feature. The frequency may also be listed as a fraction. The first number of the fraction is how many people had the symptom, and the second number is the total number of people who were examined in one study. For example, a frequency of 25/25 means that in a study of 25 people all patients were found to have that symptom. Because these frequencies are based on a specific study, the fractions may be different if another group of patients are examined. Sometimes, no information on frequency is available. In these cases, the sign or symptom may be rare or common.
Q69
Genetic mutaion
my son born with alopicia totalis and swealling around the eyes , we have done for him Whole Exome Sequencing , they identified a heterozygous likely pathogenic variant in the SOX18 gene, which supports the clinical diagnosis of hypotrichosis-lymphedema-telangiectasia syndrome , i would like to know if i can trat this or any thing that we can do to help the symptos ,pleae help
hypotrichosis-lymphedema-telangiectasia syndrome
treatment
Q69-S1-A1
153
Hypotrichosis-lymphedema-telangiectasia syndrome (HLTS) is a rare condition that, as the name suggests, is associated with sparse hair (hypotrichosis), lymphedema, and telangiectasia, particularly on the palms of the hands. Symptoms usually begin at birth or in early childhood and become worse over time. HLTS is thought to be caused by changes (mutations) in the SOX18 gene. It can follow both an autosomal dominant or an autosomal recessive pattern of inheritance, depending on the affected family. There is currently no cure for the condition. Treatment is based on the signs and symptoms present in each person.
Q70
Medical Diagnosis of Asbestosis
My doctors hint that I have asbestosis but do not say I have asbestosis. All the medical information that I have read from the CDC, Medlin and NIH all say that the symptoms presented are related to a high level of asbestos. Why won't the doctor say it?
asbestosis
diagnosis
Q70-S1-A1
154
When listening to the chest with a stethoscope, the doctor may hear crackling sounds called rales. These tests may help diagnose the disease: - Chest x-ray - CT scan of the lungs - Pulmonary function tests
Q71
Asking about Hairy cell leukemia
I get report for my father from hospital it is saying that he have Hairy cell leukemia i am here to ask if this dissease dangerous and there is treatment for it Also if The one who have it will live for long or not ? My father age is 55 We discover the dissease by blood test
hairy cell leukemia
information
Q71-S1-A1
155
Hairy cell leukemia (HCL) is an unusual cancer of the blood. It affects B cells, a type of white blood cell (lymphocyte).
Q71
Asking about Hairy cell leukemia
I get report for my father from hospital it is saying that he have Hairy cell leukemia i am here to ask if this dissease dangerous and there is treatment for it Also if The one who have it will live for long or not ? My father age is 55 We discover the dissease by blood test
hairy cell leukemia
information
Q71-S1-A2
156
Hairy cell leukemia is a rare, slow-growing cancer of the blood in which the bone marrow makes too many B cells (lymphocytes), a type of white blood cell that fights infection. The condition is named after these excess B cells which look 'hairy' under a microscope. As the number of leukemia cells increases, fewer healthy white blood cells, red blood cells and platelets are produced. The underlying cause of this condition is unknown. While there is no cure, treatment can lead to remission which can last for years.
Q71
Asking about Hairy cell leukemia
I get report for my father from hospital it is saying that he have Hairy cell leukemia i am here to ask if this dissease dangerous and there is treatment for it Also if The one who have it will live for long or not ? My father age is 55 We discover the dissease by blood test
hairy cell leukemia
treatment
Q71-S2-A1
157
Treatment may not be needed for the early stages of this disease. Some patients may need an occasional blood transfusion. If treatment is needed because of very low blood counts, chemotherapy drugs can be used. In most cases, chemotherapy can relieve the symptoms for many years. (When the signs and symptoms go away, you are said to be in remission.) Removing the spleen may improve blood counts, but is unlikely to cure the disease. Antibiotics can be used to treat infections. People with low blood counts will receive growth factors and, possibly, transfusions.
Q71
Asking about Hairy cell leukemia
I get report for my father from hospital it is saying that he have Hairy cell leukemia i am here to ask if this dissease dangerous and there is treatment for it Also if The one who have it will live for long or not ? My father age is 55 We discover the dissease by blood test
hairy cell leukemia
prognosis
Q71-S3-A1
158
Most patients with hairy cell leukemia can expect to live 10 years or longer after diagnosis and treatment.
Q72
Diabetes Type 2
I test before going to bed and the reading is 94 but when I test again in the morning, the reading is 165. How can I lower it? I eat dinner around 8PM and nothing until the next morning.
diabetes type 2
treatment
Q72-S1-A1
159
Type 2 diabetes may be reversed with lifestyle changes, especially losing weight with exercise and by eating healthier foods. Some cases of type 2 diabetes can also be improved with weight-loss surgery. There is no cure for type 1 diabetes. Treating either type 1 diabetes or type 2 diabetes involves medicines, diet, and exercise to control blood sugar level. Everyone with diabetes should receive proper education and support about the best ways to manage their diabetes. Ask your provider about seeing a diabetes nurse educator. Getting better control over your blood sugar, cholesterol, and blood pressure levels helps reduce the risk of kidney disease, eye disease, nervous system disease, heart attack, and stroke. To prevent diabetes complications, visit your provider at least 2 to 4 times a year. Talk about any problems you are having. Follow your provider's instructions on managing your diabetes.
Q72
Diabetes Type 2
I test before going to bed and the reading is 94 but when I test again in the morning, the reading is 165. How can I lower it? I eat dinner around 8PM and nothing until the next morning.
diabetes type 2
treatment
Q72-S1-A2
160
The goal of treatment at first is to lower your high blood glucose levels. Long-term goals are to prevent problems from diabetes. The most important way to treat and manage type 2 diabetes is with activity and healthy eating. Everyone with diabetes should receive proper education and support about the best ways to manage their diabetes. Ask your healthcare provider about seeing a diabetes educator. LEARN THESE SKILLS Learning diabetes management skills will help you live well with diabetes. These skills help prevent health problems and the need for medical care. Skills include: - How to test and record your blood glucose - What and when to eat - How to safely increase your activity and control your weight - How to take medications, if needed - How to recognize and treat low and high blood sugar - How to handle sick days - Where to buy diabetes supplies and how to store them It may take several months to learn these skills. Keep learning about diabetes, its complications, and how to control and live well with the disease. Stay up-to-date on new research and treatments. MANAGING YOUR BLOOD SUGAR Checking your blood sugar levels yourself and writing down the results tells you how well you are managing your diabetes. Talk to your doctor and diabetes educator about how often to check. To check your blood sugar level, you use a device called a glucose meter. Usually, you prick your finger with a small needle called a lancet. This gives you a tiny drop of blood. You place the blood on a test strip and put the strip into the meter. The meter gives you a reading that tells you the level of your blood sugar. Your doctor or diabetes educator will help set up a testing schedule for you. Your doctor will help you set a target range for your blood sugar numbers. Keep these factors in mind: - Most people with type 2 diabetes only need to check their blood sugar once or twice a day. - If your blood sugar level is under control, you may only need to check it a few times a week. - You may test yourself when you wake up, before meals, and at bedtime. - You may need to test more often when you are sick or under stress. Keep a record of your blood sugar for yourself and your doctor. Based on your numbers, you may need to make changes to your meals, activity, or medicines to keep your blood sugar level in the right range. HEALTHY EATING AND WEIGHT CONTROL Work closely with your doctor, nurse, and dietitian to learn how much fat, protein, and carbohydrates you need in your diet. Your meal plans should fit your lifestyle and habits and should include foods that you like. Managing your weight and having a well-balanced diet are important. Some people with type 2 diabetes can stop taking medicines after losing weight. This does not mean that their diabetes is cured. They still have diabetes. Very obese patients whose diabetes is not well managed with diet and medicine may consider weight loss (bariatric) surgery. REGULAR PHYSICAL ACTIVITY Regular activity is important for everyone. It is even more important when you have diabetes. Exercise is good for your health because it: - Lowers your blood sugar level without medicine - Burns extra calories and fat to help manage your weight - Improves blood flow and blood pressure - Increases your energy level - Improves your ability to handle stress Talk to your doctor before starting any exercise program. People with type 2 diabetes may need to take special steps before, during, and after physical activity or exercise. MEDICATIONS TO TREAT DIABETES If diet and exercise do not help keep your blood sugar at normal or near-normal levels, your doctor may prescribe medication. Since these drugs help lower your blood sugar levels in different ways, your doctor may have you take more than one drug. Some of the most common types of medication are listed below. They are taken by mouth or injection. - Alpha-glucosidase inhibitors - Biguanides - DPP IV inhibitors - Injectable medicines (GLP-1 analogs) - Meglitinides - SGL T2 inhibitors - Sulfonylureas - Thiazolidinediones You may need to take insulin if your blood sugar cannot be controlled with any of the above medicines. Insulin must be injected under the skin using a syringe, insulin pen, or pump. It cannot be taken by mouth because the acid in the stomach destroys insulin. PREVENTING COMPLICATIONS Your doctor may prescribe medicines or other treatments to reduce your chance of developing some of the more common complications of diabetes, including: - Eye disease - Kidney disease - Heart disease and stroke FOOT CARE People with diabetes are more likely than those without diabetes to have foot problems. Diabetes damages the nerves. This can make you less able to feel pressure on the foot. You many not notice a foot injury until you get a severe infection. Diabetes can also damage blood vessels. Small sores or breaks in the skin may become deeper skin sores (ulcers). The affected limb may need to be amputated if these skin ulcers do not heal or become larger, deeper, or infected. To prevent problems with your feet: - Stop smoking if you smoke. - Improve control of your blood sugar. - Get a foot exam by your doctor at least twice a year and learn if you have nerve damage. - Check and care for your feet every day. This is very important when you already have nerve or blood vessel damage or foot problems. - Treat minor infections, such as athlete's foot, right away. - Use moisturizing lotion on dry skin. - Make sure you wear the right kind of shoes. Ask your doctor what type of shoe is right for you.
Q73
null
Angelman syndrome. Can a person with Angelman Syndrome have children? If so, can the disorder be passed on to offspring?
angelman syndrome
inheritance
Q73-S1-A1
161
Most cases of Angelman syndrome are not inherited, particularly those caused by a deletion in the maternal chromosome 15 or by paternal uniparental disomy. These genetic changes occur as random events during the formation of reproductive cells (eggs and sperm) or in early embryonic development. In these instances, people typically have no history of the disorder in their family. Rarely, a genetic change responsible for Angelman syndrome can be inherited. For example, it is possible for a mutation in the UBE3A gene or in the nearby region of DNA that controls gene activation to be passed from one generation to the next.
Q74
Diabetes on sugar level
What happen to diabetes patient Getting blood sugar increase by which of body in brain or stomach or urine bladder.why urine bladder become more weight that any other part of body.
diabetes
information
Q74-S1-A1
165
Summary Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. With type 1 diabetes, your body does not make insulin. With type 2 diabetes, the more common type, your body does not make or use insulin well. Without enough insulin, the glucose stays in your blood. You can also have prediabetes. This means that your blood sugar is higher than normal but not high enough to be called diabetes. Having prediabetes puts you at a higher risk of getting type 2 diabetes. Over time, having too much glucose in your blood can cause serious problems. It can damage your eyes, kidneys, and nerves. Diabetes can also cause heart disease, stroke and even the need to remove a limb. Pregnant women can also get diabetes, called gestational diabetes. Blood tests can show if you have diabetes. One type of test, the A1C, can also check on how you are managing your diabetes. Exercise, weight control and sticking to your meal plan can help control your diabetes. You should also monitor your blood glucose level and take medicine if prescribed. NIH: National Institute of Diabetes and Digestive and Kidney Diseases
Q74
Diabetes on sugar level
What happen to diabetes patient Getting blood sugar increase by which of body in brain or stomach or urine bladder.why urine bladder become more weight that any other part of body.
diabetes
information
Q74-S1-A2
166
Summary Diabetes means your blood glucose, or blood sugar, levels are too high. With type 2 diabetes, the more common type, your body does not make or use insulin well. Insulin is a hormone that helps glucose get into your cells to give them energy. Without insulin, too much glucose stays in your blood. Over time, high blood glucose can lead to serious problems with your heart, eyes, kidneys, nerves, and gums and teeth. You have a higher risk of type 2 diabetes if you are older, obese, have a family history of diabetes, or do not exercise. Having prediabetes also increases your risk. Prediabetes means that your blood sugar is higher than normal but not high enough to be called diabetes. The symptoms of type 2 diabetes appear slowly. Some people do not notice symptoms at all. The symptoms can include - Being very thirsty - Urinating often - Feeling very hungry or tired - Losing weight without trying - Having sores that heal slowly - Having blurry eyesight Blood tests can show if you have diabetes. One type of test, the A1C, can also check on how you are managing your diabetes. Many people can manage their diabetes through healthy eating, physical activity, and blood glucose testing. Some people also need to take diabetes medicines. NIH: National Institute of Diabetes and Digestive and Kidney Diseases
Q74
Diabetes on sugar level
What happen to diabetes patient Getting blood sugar increase by which of body in brain or stomach or urine bladder.why urine bladder become more weight that any other part of body.
diabetes
information
Q74-S1-A3
167
Too Much Glucose in the Blood Diabetes means your blood glucose (often called blood sugar) is too high. Your blood always has some glucose in it because your body needs glucose for energy to keep you going. But too much glucose in the blood isn't good for your health. Glucose comes from the food you eat and is also made in your liver and muscles. Your blood carries the glucose to all of the cells in your body. Insulin is a chemical (a hormone) made by the pancreas. The pancreas releases insulin into the blood. Insulin helps the glucose from food get into your cells. If your body does not make enough insulin or if the insulin doesn't work the way it should, glucose can't get into your cells. It stays in your blood instead. Your blood glucose level then gets too high, causing pre-diabetes or diabetes. Types of Diabetes There are three main kinds of diabetes: type 1, type 2, and gestational diabetes. The result of type 1 and type 2 diabetes is the same: glucose builds up in the blood, while the cells are starved of energy. Over the years, high blood glucose damages nerves and blood vessels, oftentimes leading to complications such as heart disease, stroke, blindness, kidney disease, nerve problems, gum infections, and amputation. Type 1 Diabetes Type 1 diabetes, which used to be called called juvenile diabetes or insulin-dependent diabetes, develops most often in young people. However, type 1 diabetes can also develop in adults. With this form of diabetes, your body no longer makes insulin or doesn’t make enough insulin because your immune system has attacked and destroyed the insulin-producing cells. About 5 to 10 percent of people with diabetes have type 1 diabetes. To survive, people with type 1 diabetes must have insulin delivered by injection or a pump. Learn more about type 1 diabetes here. Type 2 Diabetes Type 2 diabetes, which used to be called adult-onset diabetes or non insulin-dependent diabetes, is the most common form of diabetes. Although people can develop type 2 diabetes at any age -- even during childhood -- type 2 diabetes develops most often in middle-aged and older people. Type 2 diabetes usually begins with insulin resistance—a condition that occurs when fat, muscle, and liver cells do not use insulin to carry glucose into the body’s cells to use for energy. As a result, the body needs more insulin to help glucose enter cells. At first, the pancreas keeps up with the added demand by making more insulin. Over time, the pancreas doesn’t make enough insulin when blood sugar levels increase, such as after meals. If your pancreas can no longer make enough insulin, you will need to treat your type 2 diabetes. Learn more about type 2 diabetes here. Gestational Diabetes Some women develop gestational diabetes during the late stages of pregnancy. Gestational diabetes is caused by the hormones of pregnancy or a shortage of insulin. Although this form of diabetes usually goes away after the baby is born, a woman who has had it and her child are more likely to develop diabetes later in life. Prediabetes Prediabetes means your blood glucose levels are higher than normal but not high enough for a diagnosis of diabetes. People with prediabetes are at an increased risk for developing type 2 diabetes and for heart disease and stroke. The good news is that if you have prediabetes, you can reduce your risk of getting type 2 diabetes. With modest weight loss and moderate physical activity, you can delay or prevent type 2 diabetes. Learn more about prediabetes here. Signs of Diabetes Many people with diabetes experience one or more symptoms, including extreme thirst or hunger, a frequent need to urinate and/or fatigue. Some lose weight without trying. Additional signs include sores that heal slowly, dry, itchy skin, loss of feeling or tingling in the feet and blurry eyesight. Some people with diabetes, however, have no symptoms at all. How Many Have Diabetes? Nearly 29 million Americans age 20 or older (12.3 percent of all people in this age group) have diabetes, according to 2014 estimates from the Centers for Disease Control and Prevention (CDC). About 1.9 million people aged 20 years or older were newly diagnosed with diabetes in 2010 alone. People can get diabetes at any age, but the risk increases as we get older. In 2014, over 11 million older adults living in the U.S -- nearly 26 percent of people 65 or older -- had diabetes. See more statistics about diabetes from the National Diabetes Statistics Report 2014. (Centers for Disease Control and Prevention.) If Diabetes is Not Managed Diabetes is a very serious disease. Over time, diabetes that is not well managed causes serious damage to the eyes, kidneys, nerves, heart, gums and teeth. If you have diabetes, you are more likely than people without diabetes to have heart disease or a stroke. People with diabetes also tend to develop heart disease or stroke at an earlier age than others. The best way to protect yourself from the serious complications of diabetes is to manage your blood glucose, blood pressure and cholesterol and to avoid smoking. It is not always easy, but people who make an ongoing effort to manage their diabetes can greatly improve their overall health.
Q74
Diabetes on sugar level
What happen to diabetes patient Getting blood sugar increase by which of body in brain or stomach or urine bladder.why urine bladder become more weight that any other part of body.
diabetes
information
Q74-S1-A4
168
Diabetes means your blood glucose (often called blood sugar) is too high. Your blood always has some glucose in it because your body needs glucose for energy to keep you going. But too much glucose in the blood isn't good for your health. Glucose comes from the food you eat and is also made in your liver and muscles. Your blood carries the glucose to all of the cells in your body. Insulin is a chemical (a hormone) made by the pancreas. The pancreas releases insulin into the blood. Insulin helps the glucose from food get into your cells. If your body does not make enough insulin or if the insulin doesn't work the way it should, glucose can't get into your cells. It stays in your blood instead. Your blood glucose level then gets too high, causing pre-diabetes or diabetes.
Q75
null
TMAU. Please find a way to research TMAU And how to cure it with gene therapy. I'm tired kg smelling like fish/feces And getting talked about everyday of my life.
tmau
information
Q75-S1-A1
174
Trimethylaminuria is a disorder in which the body is unable to break down trimethylamine, a chemical compound that has a pungent odor. Trimethylamine has been described as smelling like rotting fish, rotting eggs, garbage, or urine. As this compound builds up in the body, it causes affected people to give off a strong odor in their sweat, urine, and breath. The intensity of the odor may vary over time. The odor can interfere with many aspects of daily life, affecting a person's relationships, social life, and career. Some people with trimethylaminuria experience depression and social isolation as a result of this condition.
Q75
null
TMAU. Please find a way to research TMAU And how to cure it with gene therapy. I'm tired kg smelling like fish/feces And getting talked about everyday of my life.
tmau
treatment
Q75-S2-A1
175
Although there is no cure for trimethylaminuria, the following are some ways to reduce symptoms of odor:[1][3] Avoidance of foods that contain trimethylamine and its precursors (choline, lecithin, and trimethylamine N-oxide). Trimethylamine is present in high levels in milk obtained from wheat-fed cows. Choline is present in high amounts in: eggs, liver, kidney, peas, beans, peanuts, soy products, brussels sprouts, broccoli, cabbage, and cauliflower. Trimethylamine N-oxide is present in seafood Low doses of antibiotics. This decreases the amount of trimethylamine that is made by bacteria in the intestines Laxatives can decrease the amount of time food remains in the intestines and therefore reduce the amount of trimethylamine made Nutritional supplements (activated charcoal and copper chlorophyllin) can decrease the concentration of trimethylamine in the urine Soaps with a moderate pH (between 5.5 and 6.5) can help remove the secreted trimethylamine from the skin Riboflavin (vitamin B2) supplements can enhance any existing FMO3 enzyme activity (which breaks down trimethylamine) Avoidance of exercise, stress, emotional upsets, and other factors that can promote sweating People with trimethylaminuria may also find the following to be helpful:[1] Behavioral counseling to help with depression and other psychological symptoms Genetic counseling to better understand how they developed trimethylaminuria and the risks of passing the condition on to their children NOTE: People should follow the treatment advice of their healthcare provider and should not attempt to self-administer these treatment approaches. Medications and supplements can have unintended interactions, and dietary restrictions can result in nutritional deficits. Last updated: 1/24/2017
Q76
ClinicalTrials.gov - Suggestion
Please help me with my brother with locked-in syndrome in [LOCATION] for 3 years.Somebody please help. God bless .[NAME] [CONTACT]
locked-in syndrome
treatment
Q76-S1-A1
176
There is no cure for locked-in syndrome, nor is there a standard course of treatment. A therapy called functional neuromuscular stimulation, which uses electrodes to stimulate muscle reflexes, may help activate some paralyzed muscles. Several devices to help communication are available. Other treatment is symptomatic and supportive.
Q77
null
I would appreciate it if you can send me or email me some exercises for a person who is a stroke victim. I am unable to walk due to a arthritic knee. otherwise I am flexable.. my home address is [CONTACT], My email is [CONTACT] (mailto:[CONTACT]) Thank you, [NAME]
stroke
treatment
Q77-S1-A1
177
A stroke is a medical emergency. Quick treatment is needed. Call 9-1-1 or your local emergency number right away or seek urgent medical care at the first signs of a stroke. People who are having stroke symptoms need to get to a hospital as quickly as possible. - If the stroke is caused by a blood clot, a clot-busting drug may be given to dissolve the clot. - To be effective, this treatment must be started within 3 to 4 1/2 hours of when the symptoms first started. The sooner this treatment is started, the better the chance of a good outcome. Other treatments given in the hospital depend on the cause of the stroke. These may include: - Blood thinners such as heparin, warfarin (Coumadin), aspirin, or clopidogrel (Plavix) - Medicine to control risk factors, such as high blood pressure, diabetes, and high cholesterol - Special procedures or surgery to relieve symptoms or prevent more strokes - Nutrients and fluids Physical therapy, occupational therapy, speech therapy, and swallowing therapy will all begin in the hospital. If the person has severe swallowing problems, a feeding tube in the stomach (gastrostomy tube) will likely be needed. The goal of treatment after a stroke is to help you recover as much function as possible and prevent future strokes. Recovery from your stroke will begin while you are still in the hospital or at a rehabilitation center. It will continue when you go home from the hospital or center. Be sure to follow up with your health care provider after you go home.
Q77
null
I would appreciate it if you can send me or email me some exercises for a person who is a stroke victim. I am unable to walk due to a arthritic knee. otherwise I am flexable.. my home address is [CONTACT], My email is [CONTACT] (mailto:[CONTACT]) Thank you, [NAME]
stroke
treatment
Q77-S1-A2
178
Generally there are three treatment stages for stroke: prevention, therapy immediately after the stroke, and post-stroke rehabilitation. Therapies to prevent a first or recurrent stroke are based on treating an individual's underlying risk factors for stroke, such as hypertension, atrial fibrillation, and diabetes. Acute stroke therapies try to stop a stroke while it is happening by quickly dissolving the blood clot causing an ischemic stroke or by stopping the bleeding of a hemorrhagic stroke. Post-stroke rehabilitation helps individuals overcome disabilities that result from stroke damage. Medication or drug therapy is the most common treatment for stroke. The most popular classes of drugs used to prevent or treat stroke are antithrombotics (antiplatelet agents and anticoagulants) and thrombolytics.
Q77
null
I would appreciate it if you can send me or email me some exercises for a person who is a stroke victim. I am unable to walk due to a arthritic knee. otherwise I am flexable.. my home address is [CONTACT], My email is [CONTACT] (mailto:[CONTACT]) Thank you, [NAME]
stroke
treatment
Q77-S1-A3
179
With stroke, treatment depends on the stage of the disease. There are three treatment stages for stroke: prevention, therapy immediately after stroke, and rehabilitation after stroke. Stroke treatments include medications, surgery, and rehabilitation.
Q78
Psoriasis for past 7-8 years
I had psoriasis on my scalp for nearly 10 years. Please give suggestions and medications.
psoriasis
treatment
Q78-S1-A1
182
The goal of treatment is to control your symptoms and prevent infection. Three treatment options are available: - Skin lotions, ointments, creams, and shampoos. These are called topical treatments. - Pills or injections that affect the body's immune response, not just the skin. These are called systemic, or body-wide, treatments. - Phototherapy, which uses ultraviolet light to treat psoriasis. TREATMENTS USED ON THE SKIN (TOPICAL) Most of the time, psoriasis is treated with medicines that are placed directly on the skin or scalp. These may include: - Cortisone creams and ointments - Creams or ointments that contain coal tar or anthralin - Creams to remove the scaling (usually salicylic acid or lactic acid) - Dandruff shampoos (over-the-counter or prescription) - Moisturizers - Prescription medicines containing vitamin D or vitamin A (retinoids) SYSTEMIC (BODY-WIDE) TREATMENTS If you have very severe psoriasis, your provider will likely recommend medicines that suppress the immune system's faulty response. These medicines include methotrexate or cyclosporine. Retinoids can also be used. Newer drugs called biologics are used when other treatments do not work. Biologics approved for the treatment of psoriasis include: - Adalimumab (Humira) - Etanercept (Enbrel) - Infliximab (Remicade) - Ustekinumab (Stelara) - Secukinumab (Cosentyx) - Apremilast (Otezla) PHOTOTHERAPY Some people may choose to have phototherapy: - This is treatment in which your skin is carefully exposed to ultraviolet light. - It may be given alone or after you take a drug that makes the skin sensitive to light. - Phototherapy for psoriasis can be given as ultraviolet A (UVA) or ultraviolet B (UVB) light. OTHER TREATMENTS If you have an infection, your provider will prescribe antibiotics. HOME CARE Following these tips at home may help: - Taking a daily bath or shower. Try not to scrub too hard because this can irritate the skin and trigger an attack. - Oatmeal baths may be soothing and may help to loosen scales. You can use over-the-counter oatmeal bath products. Or, you can mix 1 cup of oatmeal into a tub of warm water. - Keeping your skin clean and moist, and avoiding your specific psoriasis triggers may help reduce the number of flare-ups. - Sunlight may help your symptoms go away. Be careful not to get sunburned. - Relaxation and anti-stress techniques. The link between stress and flares of psoriasis is not well understood. - Limiting the alcoholic beverages you drink may help keep psoriasis from getting worse.
Q78
Psoriasis for past 7-8 years
I had psoriasis on my scalp for nearly 10 years. Please give suggestions and medications.
psoriasis
treatment
Q78-S1-A2
184
The goals of psoriasis treatment are to change the course of the disease by interfering with the increased production of skin cells, and to remove scales and smooth rough skin. There are many types of treatments. Many are medicines and other treatments your doctor will have to prescribe. But there are other types of treatments you can buy without a prescription or try on your own. Some treatments for psoriasis are applied directly to the skin. Some use light to treat skin lesions. Others are taken by mouth or injected. This chapter focuses on treatments that are applied directly to the skin -- also called topical treatments or light therapy. Topical Treatments Here are some different types of topical treatments for psoriasis. - helps soften and loosen skin scales - comes as a cream, lotion, liquid, gel, ointment or shampoo. helps soften and loosen skin scales comes as a cream, lotion, liquid, gel, ointment or shampoo. - reduce inflammation and slow the growth and build-up of skin cells - are used in different strengths for different parts of the body. reduce inflammation and slow the growth and build-up of skin cells are used in different strengths for different parts of the body. - works by slowing the production of skin cells - is often combined with a steroid for added effects - may be used with UVB light. works by slowing the production of skin cells is often combined with a steroid for added effects may be used with UVB light. - is used to treat long-term psoriasis and hard-to-treat plaques - reduces inflammation - slows down the growth of skin cells. is used to treat long-term psoriasis and hard-to-treat plaques reduces inflammation slows down the growth of skin cells. - cause the skin to shed dead cells - slow the growth of skin cells - decrease itching. cause the skin to shed dead cells slow the growth of skin cells decrease itching. - are believed to work by reducing skin cell overgrowth - decrease inflammation - are often used with other treatments. are believed to work by reducing skin cell overgrowth decrease inflammation are often used with other treatments. - slow down the growth of skin cells - may be used with steroid creams for added effects. slow down the growth of skin cells may be used with steroid creams for added effects. Regardless of the topical medication your doctor prescribes, it is important to follow directions carefully. Some can be messy and stain your clothing and bedding. Others can have potentially dangerous side effects. Light Therapy Light therapy, also called phototherapy, uses ultraviolet light to treat skin lesions. Laser therapy delivers intense, focused doses of light to specific areas of the skin to clear lesions without harming surrounding tissues. Here are some different kinds of light therapy. UVB phototherapy - penetrates the skin to slow the growth of affected cells - is given at home or at the doctor’s office - may be combined with topical treatments or injected or oral medicines to increase effectiveness. penetrates the skin to slow the growth of affected cells is given at home or at the doctor’s office may be combined with topical treatments or injected or oral medicines to increase effectiveness. Excimer laser - targets select areas of skin with a beam of high-intensity UVB light - is used to treat chronic, localized psoriasis plaques - may take 4 to 10 sessions to see results . targets select areas of skin with a beam of high-intensity UVB light is used to treat chronic, localized psoriasis plaques may take 4 to 10 sessions to see results . Pulsed dye laser - uses a dye and different wavelength of light from other skin treatments - destroys tiny blood vessels that help psoriasis lesions form - may take 4 to 6 sessions to clear treated lesions. uses a dye and different wavelength of light from other skin treatments destroys tiny blood vessels that help psoriasis lesions form may take 4 to 6 sessions to clear treated lesions.
Q78
Psoriasis for past 7-8 years
I had psoriasis on my scalp for nearly 10 years. Please give suggestions and medications.
psoriasis
treatment
Q78-S1-A3
185
While many psoriasis treatments are applied directly to the skin, your doctor may prescribe others that must be taken by mouth or injected. There are also some natural treatments, taken by mouth or applied to the skin, that you can try on your own. Systemic Therapies These therapies, prescribed by your doctor, work in different ways to help control the underlying disease process. It is important to learn as much as you can about these medications and to take them exactly as prescribed by your doctor. Oral or injected medications for psoriasis include the following. - is used to treat severe psoriasis (meaning more than 20 percent of skin is affected) - slows the rapid growth of skin cells - is taken by mouth or injected. is used to treat severe psoriasis (meaning more than 20 percent of skin is affected) slows the rapid growth of skin cells is taken by mouth or injected. - may be used for severe psoriasis not controlled by methotrexate - suppresses overactive T cells that play a role in psoriasis - is taken by mouth or injected. may be used for severe psoriasis not controlled by methotrexate suppresses overactive T cells that play a role in psoriasis is taken by mouth or injected. - are man-made drugs related to vitamin A - help slow the production of skin cells - reduce inflammation. are man-made drugs related to vitamin A help slow the production of skin cells reduce inflammation. - are made from living cells grown in a laboratory - block the action of specific cells and proteins that play a role in psoriasis - must be injected beneath the skin or given intravenously (by IV). are made from living cells grown in a laboratory block the action of specific cells and proteins that play a role in psoriasis must be injected beneath the skin or given intravenously (by IV). Natural Treatments For many people, natural treatments can help relieve the symptoms of psoriasis. There are many natural treatments you can try on your own, but you should never use them to replace the treatment your doctor prescribes. Here are some natural treatments you may want to try. Spending a few minutes in the summer sun can help your psoriasis, but be sure to use sun block and increase time spent in the sun gradually. Applying cream from the aloe vera plant improves symptoms for some people. You should avoid aloe vera tablets. Taking fish oil orally helps some people with psoriasis. If you want to try fish oil, first speak with your doctor, as it may interact with other medications you are taking. Soaking in a solution of Dead Sea salts may improve scaling and itching. Be sure to apply moisturizer when you get out of the tub. Capsaicin, the ingredient that makes cayenne peppers hot, is the active ingredient in some topical pain-relievers. Some people find they relieve pain and itching.
Q79
Louis Bar Syndrome
My brother died young from Louis Bar Syndrome. Of six pregnancies, four children either did not survive pregnancy or died very young. I would like to know is it possible that other children (like me) could have the syndrome symptoms to a lesser or greater degree:i.e., is there a continuum???
louis bar syndrome
inheritance
Q79-S1-A1
186
Ataxia-telangiectasia is inherited in an autosomal recessive pattern, which means both copies of the ATM gene in each cell have mutations. Most often, the parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but do not show signs and symptoms of the condition. About 1 percent of the United States population carries one mutated copy and one normal copy of the ATM gene in each cell. These individuals are called carriers. Although ATM mutation carriers do not have ataxia-telangiectasia, they are more likely than people without an ATM mutation to develop cancer; female carriers are particularly at risk for developing breast cancer. Carriers of a mutation in the ATM gene also may have an increased risk of heart disease.
Q80
Bruxism
I understand that bruxism may be a result of tension or anxiety, but why that particular release? Why don't people clench their fists during sleep, or kick, or any number of activities? In other words, why is the jaw the most common location?
bruxism
cause
Q80-S1-A1
187
People can clench and grind without being aware of it. It can happen during both the day and night, although sleep-related bruxism is often a bigger problem because it is harder to control. There is some disagreement about the cause of bruxism. Daily stress may be the trigger in many people. Some people probably clench their teeth and never feel symptoms. Factors that influence whether or not bruxism causes pain and other problems will vary from person to person. They may include: - How much stress you are under - How long and tightly you clench and grind - Whether your teeth are misaligned - Your posture - Your ability to relax - Your diet - Your sleeping habits
Q80
Bruxism
I understand that bruxism may be a result of tension or anxiety, but why that particular release? Why don't people clench their fists during sleep, or kick, or any number of activities? In other words, why is the jaw the most common location?
bruxism
information
Q80-S2-A1
188
Bruxism (BRUK-siz-um) is a condition in which you grind, gnash or clench your teeth. If you have bruxism, you may unconsciously clench your teeth together during the day, or clench or grind them at night (sleep bruxism). Sleep bruxism is considered a sleep-related movement disorder. People who clench or grind their teeth (brux) during sleep are more likely to have other sleep disorders, such as snoring and pauses in breathing (sleep apnea). Mild bruxism may not require treatment. However, in some people, bruxism can be frequent and severe enough to lead to jaw disorders, headaches, damaged teeth and other problems. Because you may have sleep bruxism and be unaware of it until complications develop, it's important to know the signs and symptoms of bruxism and to seek regular dental care.
Q81
Insomnia (special case)
Hi, Im 40 years old male. I was suffering from social anxiety since I was child. Last year, I decided to go to a psychologist. She advised me to practice meditation, mindfulness and CBT as well. She explained to me the great positive impact of the meditation, mindfulness on the brain activity (neuroplasticity). Since then, I've been practicing these techniques. The result was awesome. I no longer suffer from my social anxiety and my life has completely changed to the positive side. No more worry, stress, anxiety, etc. But at the same time, I started to suffer from chronic insomnia until now. Of course, Im always in touch with my psychiatrist who has prescribed me the necessary and still following me up. Even tough, my insomnia doesn't improved. Unfortunately, nobody can determine the real cause of my insomnia. If I know the cause, I'll do my best to find the key to resolve this problem. According to my mentioned story, can you help me to find the real cause of my insomnia? Thank you, Your answer is very appreciable and important to me. [NAME].
insomnia
cause
Q81-S1-A1
192
Secondary Insomnia Secondary insomnia is the symptom or side effect of another problem. This type of insomnia often is a symptom of an emotional, neurological, or other medical or sleep disorder. Emotional disorders that can cause insomnia include depression, anxiety, and posttraumatic stress disorder. Alzheimer's disease and Parkinson's disease are examples of neurological disorders that can cause insomnia. Many other disorders or factors also can cause insomnia, such as: Conditions that cause chronic (ongoing) pain, such as arthritis and headache disorders Conditions that make it hard to breathe, such as asthma and heart failure An overactive thyroid Gastrointestinal disorders, such as heartburn Stroke Sleep disorders, such as restless legs syndrome and sleep-related breathing problems Menopause and hot flashes Secondary insomnia also can be a side effect of some medicines. For example, certain asthma medicines, such as theophylline, and some allergy and cold medicines can cause insomnia. Beta blockers also can cause the condition. These medicines are used to treat heart conditions. Commonly used substances also can cause insomnia. Examples include caffeine and other stimulants, tobacco and other nicotine products, and alcohol and other sedatives. Primary Insomnia Primary insomnia isn't a symptom or side effect of another medical condition. It is its own distinct disorder, and its cause isn’t well understood. Primary insomnia usually lasts for at least 1 month. Many life changes can trigger primary insomnia. It may be due to major or long-lasting stress or emotional upset. Travel or other factors, such as work schedules that disrupt your sleep routine, also may trigger primary insomnia. Even if these issues are resolved, the insomnia may not go away. Trouble sleeping can persist because of habits formed to deal with the lack of sleep. These habits might include taking naps, worrying about sleep, and going to bed early. Researchers continue to try to find out whether some people are born with an increased risk for primary insomnia.
Q82
null
would you help me to fine article or jurnal about Cri du chat syndrome
cri du chat syndrome
information
Q82-S1-A1
194
Cri-du-chat (cat's cry) syndrome, also known as 5p- (5p minus) syndrome, is a chromosomal condition that results when a piece of chromosome 5 is missing. Infants with this condition often have a high-pitched cry that sounds like that of a cat. The disorder is characterized by intellectual disability and delayed development, small head size (microcephaly), low birth weight, and weak muscle tone (hypotonia) in infancy. Affected individuals also have distinctive facial features, including widely set eyes (hypertelorism), low-set ears, a small jaw, and a rounded face. Some children with cri-du-chat syndrome are born with a heart defect. These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional. Where to Start Genetics Home Reference (GHR) contains information on Cri du chat syndrome. This website is maintained by the National Library of Medicine. MedlinePlus was designed by the National Library of Medicine to help you research your health questions, and it provides more information about this topic. The National Human Genome Research Institute's (NHGRI) website has an information page on this topic. NHGRI is part of the National Institutes of Health and supports research on the structure and function of the human genome and its role in health and disease. The National Organization for Rare Disorders (NORD) has a report for patients and families about this condition. NORD is a patient advocacy organization for individuals with rare diseases and the organizations that serve them. In-Depth Information Medscape Reference provides information on this topic. You may need to register to view the medical textbook, but registration is free. The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition. Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine. Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge. PubMed is a searchable database of medical literature and lists journal articles that discuss Cri du chat syndrome. Click on the link to view a sample search on this topic. Selected Full-Text Journal Articles Nguyen JM et al., 5p deletions: Current knowledge and future directions. Am J Med Genet C Semin Med Genet. 2015 Sep;169(3):224-38. Boultwood J et al., Advances in the 5q- syndrome. Blood. 2010 Dec 23;116(26):5803-11. Pituch KA et al., Educational Priorities for Children with Cri-Du-Chat Syndrome. J Dev Phys Disabil. 2010 Feb;22(1):65-81. Rodríguez-Caballero A et al., Cri du chat syndrome: a critical review. Med Oral Patol Oral Cir Bucal. 2010 May 1;15(3):e473-8. Cornish K, Bramble D. Cri du chat syndrome: genotype-phenotype correlations and recommendations for clinical management. Dev Med Child Neurol. 2002 Jul;44(7):494-7.
Q83
taking multiple meds
Plavix,linisopril,simvastatin,melotonin: What possible side effects should I be aware of when taking all of these daily?
Plavix
side effects
Q83-S1-A1
195
Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness headache dizziness nausea vomiting stomach pain diarrhea nosebleed Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately: hives rash itching difficulty breathing or swallowing swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs hoarseness black and tarry stools red blood in stools bloody vomit vomit that looks like coffee grounds unusual bleeding or bruising pink or brown urine slow or difficult speech weakness or numbness of an arm or a leg changes in vision fever shortness of breath fast heartbeat pale skin purple patches or bleeding under the skin confusion yellowing of the skin or eyes seizures Clopidogrel may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Q83
taking multiple meds
Plavix,linisopril,simvastatin,melotonin: What possible side effects should I be aware of when taking all of these daily?
linisopril
side effects
Q83-S2-A1
196
Lisinopril and hydrochlorothiazide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: dizziness headache cough excessive tiredness pain, burning, or tingling in the hands or feet decrease in sexual ability heartburn Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately: swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs hoarseness difficulty breathing or swallowing stomach pain upset stomach vomiting fever, sore throat, chills, and other signs of infection muscle pain, cramps, or weakness yellowing of the skin or eyes dry mouth thirst weakness restlessness confusion seizures decrease in urination lightheadedness fainting chest pain rapid, pounding, slow, or irregular heartbeat pain in big toe tingling in arms and legs loss of muscle tone weakness or heaviness in legs lack of energy cold, gray skin Lisinopril and hydrochlorothiazide may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Q83
taking multiple meds
Plavix,linisopril,simvastatin,melotonin: What possible side effects should I be aware of when taking all of these daily?
simvastatin
side effects
Q83-S3-A1
197
Simvastatin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: constipation stomach pain nausea headache memory loss or forgetfulness confusion Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately or get emergency medical help. muscle pain, tenderness, or weakness dark red urine decreased urination lack of energy, tiredness, or weakness loss of appetite pain in the upper right part of the stomach yellowing of the skin or eyes dark colored urine fever or chills flushing blisters rash hives itching swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs difficulty breathing or swallowing hoarseness joint pain sensitivity to light This medication may cause other side effects. Call your doctor if you have any unusual problems while you are taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).
Q83
taking multiple meds
Plavix,linisopril,simvastatin,melotonin: What possible side effects should I be aware of when taking all of these daily?
melotonin
side effects
Q83-S4-A1
198
Side effects of melatonin are uncommon but can include drowsiness, headache, dizziness, or nausea. There have been no reports of significant side effects of melatonin in children.
Q84
abetalipoproteimemia
hi, I would like to know if there is any support for those suffering with abetalipoproteinemia? I am not diagnosed but have had many test that indicate I am suffering with this, keen to learn how to get it diagnosed and how to manage, many thanks
abetalipoproteinemia
diagnosis
Q84-S1-A1
199
There may be damage to the retina of the eye (retinitis pigmentosa). Tests that may be done to help diagnose this condition include: - Apolipoprotein B blood test - Blood tests to look for vitamin deficiencies (fat-soluble vitamins A, D, E, and K) - "Burr-cell" malformation of the red cells (acanthocytosis) - Complete blood count (CBC) - Cholesterol studies - Electromyography - Eye exam - Nerve conduction velocity - Stool sample analysis Genetic testing may be available for mutations in the MTP gene.
Q84
abetalipoproteimemia
hi, I would like to know if there is any support for those suffering with abetalipoproteinemia? I am not diagnosed but have had many test that indicate I am suffering with this, keen to learn how to get it diagnosed and how to manage, many thanks
abetalipoproteinemia
diagnosis
Q84-S1-A2
200
The Genetic Testing Registry (GTR) provides information about the genetic tests available for abetalipoproteinemia. The intended audience for the GTR is health care providers and researchers. Patients and consumers with specific questions about a genetic test should contact a health care provider or a genetics professional. Prenatal testing may also be available for pregnancies at increased risk if the mutations in the family have been identified.
Q84
abetalipoproteimemia
hi, I would like to know if there is any support for those suffering with abetalipoproteinemia? I am not diagnosed but have had many test that indicate I am suffering with this, keen to learn how to get it diagnosed and how to manage, many thanks
abetalipoproteinemia
treatment
Q84-S2-A1
201
Treatment involves large doses of vitamin supplements containing fat-soluble vitamins (vitamin A, vitamin D, vitamin E, and vitamin K). Linoleic acid supplements are also recommended. People with this condition should talk to a nutritionist. Diet changes are needed to prevent stomach problems. This involves: - Limiting fat intake to 5 to 20 grams per day. - Do not eat more than 5 ounces daily of lean meat, fish, or poultry. - Use skim milk instead of whole milk. Supplements of medium-chain triglycerides are taken under the supervision of a health care provider. They should be used with caution, because they may cause liver damage.
Q84
abetalipoproteimemia
hi, I would like to know if there is any support for those suffering with abetalipoproteinemia? I am not diagnosed but have had many test that indicate I am suffering with this, keen to learn how to get it diagnosed and how to manage, many thanks
abetalipoproteinemia
treatment
Q84-S2-A2
202
A nutritionist or other qualified medical professional should be consulted for specific dietary instruction in people with abetalipoproteinemia. Treatment involves very large doses of vitamin E, as well as large doses of vitamin supplements containing other fat-soluble vitamins (vitamin A, vitamin D, and vitamin K). Linoleic acid supplements are also recommended. Several diet changes and/or restrictions are also needed to prevent stomach problems. A low-fat diet may help with digestive symptoms; medium chain triglycerides may be used (under supervision of a specialist) as a source of fat in the diet. Management in adults typically focuses on specific complications associated with the disorder, and depends on the signs and symptoms present. Affected people may need consultations with several other types of specialists, including a lipidologist, gastroenterologist, hepatologist, ophthalmologist, and neurologist.
Q84
abetalipoproteimemia
hi, I would like to know if there is any support for those suffering with abetalipoproteinemia? I am not diagnosed but have had many test that indicate I am suffering with this, keen to learn how to get it diagnosed and how to manage, many thanks
abetalipoproteinemia
treatment
Q84-S2-A3
203
These resources address the diagnosis or management of abetalipoproteinemia: - Genetic Testing Registry: Abetalipoproteinaemia - MedlinePlus Encyclopedia: Bassen-Kornzweig syndrome - MedlinePlus Encyclopedia: Malabsorption - MedlinePlus Encyclopedia: Retinitis pigmentosa - MedlinePlus Encyclopedia: Stools - floating These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
Q85
prevention of preeclampsia
I know that the jury is out on the exact causes of preeclampsia, but I am looking for some of the ways that the chances of acquiring it can be minimized.
preeclampsia
prevention
Q85-S1-A1
204
There is no known way to prevent preeclampsia. It is important for all pregnant women to start prenatal care early and continue it through the pregnancy.
Q86
null
Colon cancer cure seen on tv. My father has colon cancer and said he saw a commercial on tv about a cure for colon cancer. He cannot remember any details about it. I was wondering if you know anything about something like this. Please let me know. Thank you, [NAME]
colon cancer
treatment
Q86-S1-A1
206
Treatment depends on many things, including the stage of the cancer. Treatments may include: - Surgery to remove the tumor - Chemotherapy to kill cancer cells - Radiation therapy to destroy cancerous tissue - Targeted therapy to keep cancer from growing and spreading  Surgery Stage 0 colon cancer may be treated by removing the tumor. This is done using colonoscopy. For stages I, II, and III cancer, more extensive surgery is needed to remove the part of the colon that is cancerous. This surgery is called colon resection (colectomy). Chemotherapy Almost all people with stage III colon cancer receive chemotherapy after surgery for 6 to 8 months. This is called adjuvant chemotherapy. Even though the tumor was removed, chemotherapy is given to treat any cancer cells that may be left. Chemotherapy is also used to improve symptoms and prolong survival in people with stage IV colon cancer. You may receive just one type of medicine or a combination of medicines. Radiation Radiation therapy is sometimes used for colon cancer. It is usually used in combination with chemotherapy for people with stage III rectal cancer. For people with stage IV disease that has spread to the liver, treatment directed at the liver can be used. This may include: - Burning the cancer (ablation) - Delivering chemotherapy or radiation directly into the liver - Freezing the cancer (cryotherapy) - Surgery Targeted Therapy - Targeted treatment zeroes in on specific targets (molecules) in cancer cells. These targets play a role in how cancer cells grow and survive. Using these targets, the drug disables the cancer cells so they cannot spread. Targeted therapy may be given as pills or may be injected into a vein. - You may have targeted therapy along with surgery, chemotherapy, or radiation treatment.  
Q87
IHSS heart condition and WPW heart condition
Is there any way you could send me information on both these heart conditions? My son has to get tested for them eventually and I would just like information to understand the conditions of both of them more.
IHSS heart condition
information
Q87-S1-A1
207
Hypertrophic cardiomyopathy (HCM) is a condition in which the heart muscle becomes thick. Often, only 1 part of the heart is thicker than the other parts. The thickening can make it harder for blood to leave the heart, forcing the heart to work harder to pump blood. It also can make it harder for the heart to relax and fill with blood.
Q87
IHSS heart condition and WPW heart condition
Is there any way you could send me information on both these heart conditions? My son has to get tested for them eventually and I would just like information to understand the conditions of both of them more.
wpw
information
Q87-S2-A1
208
Wolff-Parkinson-White syndrome is a condition in which there is an extra electrical pathway of the heart. The condition can lead to periods of rapid heart rate (tachycardia). Wolff-Parkinson-White syndrome is one of the most common causes of fast heart rate problems in infants and children.
Q87
IHSS heart condition and WPW heart condition
Is there any way you could send me information on both these heart conditions? My son has to get tested for them eventually and I would just like information to understand the conditions of both of them more.
wpw
information
Q87-S2-A2
209
Wolff-Parkinson-White syndrome is a condition characterized by abnormal electrical pathways in the heart that cause a disruption of the heart's normal rhythm (arrhythmia). The heartbeat is controlled by electrical signals that move through the heart in a highly coordinated way. A specialized cluster of cells called the atrioventricular node conducts electrical impulses from the heart's upper chambers (the atria) to the lower chambers (the ventricles). Impulses move through the atrioventricular node during each heartbeat, stimulating the ventricles to contract slightly later than the atria. People with Wolff-Parkinson-White syndrome are born with an extra connection in the heart, called an accessory pathway, that allows electrical signals to bypass the atrioventricular node and move from the atria to the ventricles faster than usual. The accessory pathway may also transmit electrical impulses abnormally from the ventricles back to the atria. This extra connection can disrupt the coordinated movement of electrical signals through the heart, leading to an abnormally fast heartbeat (tachycardia) and other arrhythmias. Resulting symptoms include dizziness, a sensation of fluttering or pounding in the chest (palpitations), shortness of breath, and fainting (syncope). In rare cases, arrhythmias associated with Wolff-Parkinson-White syndrome can lead to cardiac arrest and sudden death. The most common arrhythmia associated with Wolff-Parkinson-White syndrome is called paroxysmal supraventricular tachycardia. Complications of Wolff-Parkinson-White syndrome can occur at any age, although some individuals born with an accessory pathway in the heart never experience any health problems associated with the condition. Wolff-Parkinson-White syndrome often occurs with other structural abnormalities of the heart or underlying heart disease. The most common heart defect associated with the condition is Ebstein anomaly, which affects the valve that allows blood to flow from the right atrium to the right ventricle (the tricuspid valve). Additionally, Wolff-Parkinson-White syndrome can be a component of several other genetic syndromes, including hypokalemic periodic paralysis (a condition that causes episodes of extreme muscle weakness), Pompe disease (a disorder characterized by the storage of excess glycogen), and tuberous sclerosis (a condition that results in the growth of noncancerous tumors in many parts of the body).
Q88
striving to recove speech arti\culutation when traditional therapies have failed
I'm a vietnam navy veteran whose traditional stroke thearapy has failed miserably
stroke
treatment
Q88-S1-A1
210
A stroke is a medical emergency. Quick treatment is needed. Call 9-1-1 or your local emergency number right away or seek urgent medical care at the first signs of a stroke. People who are having stroke symptoms need to get to a hospital as quickly as possible. - If the stroke is caused by a blood clot, a clot-busting drug may be given to dissolve the clot. - To be effective, this treatment must be started within 3 to 4 1/2 hours of when the symptoms first started. The sooner this treatment is started, the better the chance of a good outcome. Other treatments given in the hospital depend on the cause of the stroke. These may include: - Blood thinners such as heparin, warfarin (Coumadin), aspirin, or clopidogrel (Plavix) - Medicine to control risk factors, such as high blood pressure, diabetes, and high cholesterol - Special procedures or surgery to relieve symptoms or prevent more strokes - Nutrients and fluids Physical therapy, occupational therapy, speech therapy, and swallowing therapy will all begin in the hospital. If the person has severe swallowing problems, a feeding tube in the stomach (gastrostomy tube) will likely be needed. The goal of treatment after a stroke is to help you recover as much function as possible and prevent future strokes. Recovery from your stroke will begin while you are still in the hospital or at a rehabilitation center. It will continue when you go home from the hospital or center. Be sure to follow up with your health care provider after you go home.
Q88
striving to recove speech arti\culutation when traditional therapies have failed
I'm a vietnam navy veteran whose traditional stroke thearapy has failed miserably
stroke
treatment
Q88-S1-A2
211
Generally there are three treatment stages for stroke: prevention, therapy immediately after the stroke, and post-stroke rehabilitation. Therapies to prevent a first or recurrent stroke are based on treating an individual's underlying risk factors for stroke, such as hypertension, atrial fibrillation, and diabetes. Acute stroke therapies try to stop a stroke while it is happening by quickly dissolving the blood clot causing an ischemic stroke or by stopping the bleeding of a hemorrhagic stroke. Post-stroke rehabilitation helps individuals overcome disabilities that result from stroke damage. Medication or drug therapy is the most common treatment for stroke. The most popular classes of drugs used to prevent or treat stroke are antithrombotics (antiplatelet agents and anticoagulants) and thrombolytics.
Q88
striving to recove speech arti\culutation when traditional therapies have failed
I'm a vietnam navy veteran whose traditional stroke thearapy has failed miserably
stroke
treatment
Q88-S1-A3
212
With stroke, treatment depends on the stage of the disease. There are three treatment stages for stroke: prevention, therapy immediately after stroke, and rehabilitation after stroke. Stroke treatments include medications, surgery, and rehabilitation.
Q88
striving to recove speech arti\culutation when traditional therapies have failed
I'm a vietnam navy veteran whose traditional stroke thearapy has failed miserably
stroke
treatment
Q88-S1-A4
213
Medication or drug therapy is the most common treatment for stroke. The most popular kinds of drugs to prevent or treat stroke are antithrombotics -- which include antiplatelet agents and anticoagulants -- and thrombolytics. Antithrombotics prevent the formation of blood clots that can become stuck in an artery of the brain and cause strokes. - In the case of stroke, doctors prescribe antiplatelet drugs mainly for prevention. The most widely known and used antiplatelet drug is aspirin. Other antiplatelet drugs include clopidogrel, ticlopidine, and dipyridamole. In the case of stroke, doctors prescribe antiplatelet drugs mainly for prevention. The most widely known and used antiplatelet drug is aspirin. Other antiplatelet drugs include clopidogrel, ticlopidine, and dipyridamole. - Anticoagulants reduce the risk of stroke by reducing the clotting property of the blood. The most commonly used oral anticoagulants include warfarin, also known as Coumadin®, dabigatran (Pradaxa) and rivaroxaban (Xarelto). Injectable anticoagulants include heparin, enoxaparin (Lovenox), and dalteparin (Fragmin). Anticoagulants reduce the risk of stroke by reducing the clotting property of the blood. The most commonly used oral anticoagulants include warfarin, also known as Coumadin®, dabigatran (Pradaxa) and rivaroxaban (Xarelto). Injectable anticoagulants include heparin, enoxaparin (Lovenox), and dalteparin (Fragmin). Thrombolytic drugs halt the stroke by dissolving the blood clot that is blocking blood flow to the brain. Ischemic strokes -- the most common kind -- can be treated with thrombolytic drugs. But a person needs to be at the hospital as soon as possible after symptoms start to be evaluated and receive treatment. A thrombolytic drug known as t-PA can be effective if a person receives it intravenously (in a vein) within 3 hours after his or her stroke symptoms have started. Because there is such a narrow time window for giving t-PA, it is important to note the time any stroke symptoms appear. Since thrombolytic drugs can increase bleeding, t-PA should be used only after the doctor is certain that the patient has suffered an ischemic and not a hemorrhagic stroke. Neuroprotectants are medications or other treatments that protect the brain from secondary injury caused by stroke. Although the FDA (Food and Drug Administration) has not approved any neuroprotectants for use in stroke at this time, many have been tested or are being tested in clinical trials. Cooling of the brain (hypothermia) is beneficial for improving neurological function after a cardiac arrest.
Q88
striving to recove speech arti\culutation when traditional therapies have failed
I'm a vietnam navy veteran whose traditional stroke thearapy has failed miserably
stroke
treatment
Q88-S1-A5
214
Surgery can be used to prevent stroke, to treat stroke, or to repair damage to the blood vessels or malformations in and around the brain. - Carotid endarterectomy is a surgical procedure in which a surgeon removes fatty deposits, or plaque, from the inside of one of the carotid arteries. The procedure is performed to prevent stroke. The carotid arteries are located in the neck and are the main suppliers of blood to the brain. Carotid endarterectomy is a surgical procedure in which a surgeon removes fatty deposits, or plaque, from the inside of one of the carotid arteries. The procedure is performed to prevent stroke. The carotid arteries are located in the neck and are the main suppliers of blood to the brain. Vascular Interventions In addition to surgery, a variety of techniques have been developed to allow certain vascular problems to be treated from inside the artery using specialized catheters with the goal of improving blood flow. (Vascular is a word that refers to blood vessels, arteries, and veins that carry blood throughout the body.) A catheter is a very thin, flexible tube that can be inserted into one of the major arteries of the leg or arm and then directed through the blood vessels to the diseased artery. Physicians trained in this technique called angiography undergo additional training to treat problems in the arteries of the brain or spinal cord. These physicians are called neurointerventionalists. - Angioplasty is widely used by angiographers to open blocked heart arteries, and is also used to prevent stroke. Angioplasty is a procedure in which a special catheter is inserted into the narrowed artery and then a balloon at the tip of the catheter is inflated to open the blocked artery. The procedure improves blood flow to the brain. Angioplasty is widely used by angiographers to open blocked heart arteries, and is also used to prevent stroke. Angioplasty is a procedure in which a special catheter is inserted into the narrowed artery and then a balloon at the tip of the catheter is inflated to open the blocked artery. The procedure improves blood flow to the brain. - Stenting is another procedure used to prevent stroke. In this procedure an angiographer inserts a catheter into the artery in the groin and then positions the tip of the catheter inside the narrowed artery. A stent is a tube-like device made of a mesh-like material that can be slipped into position over the catheter. When positioned inside the narrowed segment the stent is expanded to widen the artery and the catheter is removed. Angioplasty or stenting of the carotid artery can cause pieces of the diseased plaque to loosen. An umbrella-like device is often temporarily expanded above to prevent these pieces from traveling to the brain. Stenting is another procedure used to prevent stroke. In this procedure an angiographer inserts a catheter into the artery in the groin and then positions the tip of the catheter inside the narrowed artery. A stent is a tube-like device made of a mesh-like material that can be slipped into position over the catheter. When positioned inside the narrowed segment the stent is expanded to widen the artery and the catheter is removed. Angioplasty or stenting of the carotid artery can cause pieces of the diseased plaque to loosen. An umbrella-like device is often temporarily expanded above to prevent these pieces from traveling to the brain. - Angiographers also sometimes use clot removal devices to treat stroke patients in the very early stage. One device involves threading a catheter through the artery to the site of the blockage and then vacuuming out the clot. Another corkscrew-like device can be extended from the tip of a catheter and used to grab the clot and pull it out. Drugs can also be injected through the catheter directly into the clot to help dissolve the clot. Angiographers also sometimes use clot removal devices to treat stroke patients in the very early stage. One device involves threading a catheter through the artery to the site of the blockage and then vacuuming out the clot. Another corkscrew-like device can be extended from the tip of a catheter and used to grab the clot and pull it out. Drugs can also be injected through the catheter directly into the clot to help dissolve the clot.
Q89
Subcutaneous retrocalcaneal bursitis
Haglund's deformity of the calcaneum. I have this problem. Can you please help to overcome this?
haglund's deformity
treatment
Q89-S1-A1
216
Your provider may recommend that you do the following: Avoid activities that cause pain. Put ice on the heel several times a day. Take nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. Try using over-the-counter or custom heel wedges in your shoe to help decrease stress on the heel. Try ultrasound treatment during physical therapy to reduce inflammation. Have physical therapy to improve flexibility and strength around the ankle. The focus will be on stretching your Achilles tendon. This can help the bursitis improve and prevent it from coming back. If these treatments DO NOT work, your provider may inject a small amount of steroid medicine into the bursa. After the injection, you should avoid overstretching the tendon because it can break open (rupture). If the condition is connected to Achilles tendinitis, you may need to wear a cast on the ankle for several weeks. Very rarely, surgery may be needed to remove the inflamed bursa.
Q90
null
williams sydrome conditon. i need to send me more information about Williams Syndrome and some tips how to educate people with this disorder.I hope having news from you soon!!thank you
williams syndrome
information
Q90-S1-A1
217
Williams syndrome is a developmental disorder that affects many parts of the body. This condition is characterized by mild to moderate intellectual disability or learning problems, unique personality characteristics, distinctive facial features, and heart and blood vessel (cardiovascular) problems. People with Williams syndrome typically have difficulty with visual-spatial tasks such as drawing and assembling puzzles, but they tend to do well on tasks that involve spoken language, music, and learning by repetition (rote memorization). Affected individuals have outgoing, engaging personalities and tend to take an extreme interest in other people. Attention deficit disorder (ADD), problems with anxiety, and phobias are common among people with this disorder. Young children with Williams syndrome have distinctive facial features including a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips. Many affected people have dental problems such as teeth that are small, widely spaced, crooked, or missing. In older children and adults, the face appears longer and more gaunt. A form of cardiovascular disease called supravalvular aortic stenosis (SVAS) occurs frequently in people with Williams syndrome. Supravalvular aortic stenosis is a narrowing of the large blood vessel that carries blood from the heart to the rest of the body (the aorta). If this condition is not treated, the aortic narrowing can lead to shortness of breath, chest pain, and heart failure. Other problems with the heart and blood vessels, including high blood pressure (hypertension), have also been reported in people with Williams syndrome. Additional signs and symptoms of Williams syndrome include abnormalities of connective tissue (tissue that supports the body's joints and organs) such as joint problems and soft, loose skin. Affected people may also have increased calcium levels in the blood (hypercalcemia) in infancy, developmental delays, problems with coordination, and short stature. Medical problems involving the eyes and vision, the digestive tract, and the urinary system are also possible.
Q90
null
williams sydrome conditon. i need to send me more information about Williams Syndrome and some tips how to educate people with this disorder.I hope having news from you soon!!thank you
williams syndrome
information
Q90-S1-A2
218
Williams Syndrome (WS) is a rare genetic disorder characterized by mild to moderate delays in cognitive development or learning difficulties, a distinctive facial appearance, and a unique personality that combines over-friendliness and high levels of empathy with anxiety. The most significant medical problem associated with WS is cardiovascular disease caused by narrowed arteries. WS is also associated with elevated blood calcium levels in infancy. A random genetic mutation (deletion of a small piece of chromosome 7), rather than inheritance, most often causes the disorder.  However, individuals who have WS have a 50 percent chance of passing it on if they decide to have children.  The characteristic facial features of WS include puffiness around the eyes, a short nose with a broad nasal tip, wide mouth, full cheeks, full lips, and a small chin. People with WS are also likely to have a long neck, sloping shoulders, short stature, limited mobility in their joints, and curvature of the spine.  Some individuals with WS have a star-like pattern in the iris of their eyes.  Infants with WS are often irritable and colicky, with feeding problems that keep them from gaining weight.  Chronic abdominal pain is common in adolescents and adults. By age 30, the majority of individuals with WS have diabetes or pre-diabetes and mild to moderate sensorineural hearing loss (a form of deafness due to disturbed function of the auditory nerve).  For some people, hearing loss may begin as early as late childhood. WS also is associated with a characteristic “cognitive profile” of mental strengths and weaknesses composed of strengths in verbal short-term memory and language, combined with severe weakness in visuospatial construction (the skills used to copy patterns, draw, or write). Within language, the strongest skills are typically in concrete, practical vocabulary, which in many cases is in the low average to average range for the general population. Abstract or conceptual-relational vocabulary is much more limited. Most older children and adults with WS speak fluently and use good grammar.  More than 50% of children with WS have attention deficit disorders (ADD or ADHD), and about 50% have specific phobias, such as a fear of loud noises. The majority of individuals with WS worry excessively. The National Institutes of Health (NIH), and the National Institute of Neurological Disorders and Stroke (NINDS), have funded many of the research studies exploring the genetic and neurobiological origins of WS.  In the early 1990s, researchers located and identified the genetic mutation responsible for the disorder: the deletion of a small section of chromosome 7 that contains approximately 25 genes.  NINDS continues to support WS researchers including, for example, groups that are attempting to link specific genes with the corresponding facial, cognitive, personality, and neurological characteristics of WS.
Q91
null
Please i want to know the cure to Adenomyosis. I have been going through alot of pains during my menstruation. I want to see a specialist doctor to help me out. I am dying with pains.
adenomyosis
treatment
Q91-S1-A1
224
Most women have some adenomyosis as they get close to menopause. However, only a few will have symptoms. Most women do not need treatment. Birth control pills and a progesterone-containing intrauterine device (IUD) can help decrease heavy bleeding. Anti-inflammatory medication such as ibuprofen or naproxen can also help manage symptoms. A hysterectomy may be necessary in women with severe symptoms.
Q92
muscular dystrophy medicine
My brother need treatment for muscular dystrophy
muscular dystrophy
treatment
Q92-S1-A1
225
There are no known cures for the various muscular dystrophies. The goal of treatment is to control symptoms. Physical therapy may help maintain muscle strength and function. Leg braces and a wheelchair can improve mobility and self-care. In some cases, surgery on the spine or legs may help improve function. Corticosteroids taken by mouth are sometimes prescribed to children with certain muscular dystrophies to keep them walking for as long as possible. The person should be as active as possible. No activity at all (such as bedrest) can make the disease worse.
Q92
muscular dystrophy medicine
My brother need treatment for muscular dystrophy
muscular dystrophy
treatment
Q92-S1-A2
226
There is no specific treatment to stop or reverse any form of MD. Treatment may include physical therapy, respiratory therapy, speech therapy, orthopedic appliances used for support, and corrective orthopedic surgery. Drug therapy includes corticosteroids to slow muscle degeneration, anticonvulsants to control seizures and some muscle activity, immunosuppressants to delay some damage to dying muscle cells, and antibiotics to fight respiratory infections. Some individuals may benefit from occupational therapy and assistive technology. Some patients may need assisted ventilation to treat respiratory muscle weakness and a pacemaker for cardiac abnormalities.
Q93
null
What ia the lowest starting dose of Citalopram?
Citalopram
dosage
Q93-S1-A1
227
Initial Treatment Celexa (citalopram HBr) should be administered at an initial dose of 20 mg once daily, generally with an increase to a dose of 40 mg/day. Dose increases should usually occur in increments of 20 mg at intervals of no less than one week. Although certain patients may require a dose of 60 mg/day, the only study pertinent to dose response for effectiveness did not demonstrate an advantage for the 60 mg/day dose over the 40 mg/day dose; doses above 40 mg are therefore not ordinarily recommended. Celexa should be administered once daily, in the morning or evening, with or without food. Special Populations 20 mg/day is the recommended dose for most elderly patients and patients with hepatic impairment, with titration to 40 mg/day only for nonresponding patients. No dosage adjustment is necessary for patients with mild or moderate renal impairment. Celexa should be used with caution in patients with severe renal impairment. Treatment of Pregnant Women During the Third Trimester Neonates exposed to Celexa and other SSRIs or SNRIs, late in the third trimester, have developed complications requiring prolonged hospitalization, respiratory support, and tube feeding (see PRECAUTIONS). When treating pregnant women with Celexa during the third trimester, the physician should carefully consider the potential risks and benefits of treatment. The physician may consider tapering Celexa in the third trimester. Maintenance Treatment It is generally agreed that acute episodes of depression require several months or longer of sustained pharmacologic therapy. Systematic evaluation of Celexa in two studies has shown that its antidepressant efficacy is maintained for periods of up to 24 weeks following 6 or 8 weeks of initial treatment (32 weeks total). In one study, patients were assigned randomly to placebo or to the same dose of Celexa (20-60 mg/day) during maintenance treatment as they had received during the acute stabilization phase, while in the other study, patients were assigned randomly to continuation of Celexa 20 or 40 mg/day, or placebo, for maintenance treatment. In the latter study, the rates of relapse to depression were similar for the two dose groups (see Clinical Trials under CLINICAL PHARMACOLOGY). Based on these limited data, it is not known whether the dose of citalopram needed to maintain euthymia is identical to the dose needed to induce remission. If adverse reactions are bothersome, a decrease in dose to 20 mg/day can be considered. Discontinuation of Treatment with Celexa Symptoms associated with discontinuation of Celexa and other SSRIs and SNRIs have been reported (see PRECAUTIONS). Patients should be monitored for these symptoms when discontinuing treatment. A gradual reduction in the dose rather than abrupt cessation is recommended whenever possible. If intolerable symptoms occur following a decrease in the dose or upon discontinuation of treatment, then resuming the previously prescribed dose may be considered. Subsequently, the physician may continue decreasing the dose but at a more gradual rate. Switching Patients To or From a Monoamine Oxidase Inhibitor At least 14 days should elapse between discontinuation of an MAOI and initiation of Celexa therapy. Similarly, at least 14 days should be allowed after stopping Celexa before starting an MAOI (see CONTRAINDICATIONS and WARNINGS).
Q94
null
ClinicalTrials.gov - General Complaint. I have had undisguised ADHD since I was 8 years old. I sold illicit drugs from 1979-1989 in large quantity's & self medicated with amphetamines as an adolescent which damaged my Brian & worsened my symptoms. Because I have had several drug induced psychotic episodes since I was busted for trafficking in 1989 & was unable to self medicate on a daily basis. I was wrongly diagnosed with schizophrenia 9years ago. The community psychiatrist's have treated me with all the wrong medication's that have made my ADHD symptoms worse & forced me to self medicate until now. I have no assets or money & I don't think it is worth while going on with out being put on the right medication Ritalin. When I take Meth amphetamines my symptoms improve & I haven't had any anti psychotic medication for 13 month's & have not gone psychotic or had any negative symptoms of schizophrenia. Can you suggest any type of tests I can do to prove I have Adult ADHD or a psychiatrist I can see in [LOCATION] Australia. Who can help me
adhd
diagnosis
Q94-S1-A1
228
If ADHD is suspected, the person should be evaluated by a health care professional. There is no test that can make or exclude a diagnosis of ADHD. The diagnosis is based on a pattern of the symptoms listed below. When the person with suspected ADHD is a child, parents and teachers are usually involved during the evaluation process. Most children with ADHD have at least one other developmental or mental health problem. This problem may be a mood, anxiety or substance use disorder; a learning disability; or a tic disorder. A doctor can help determine whether these other conditions are present. Symptoms ADHD symptoms fall into three groups: Not being able to focus (inattentiveness) Being extremely active (hyperactivity) Not being able to control behavior (impulsivity) Some people with ADHD have mainly inattentive symptoms. Some have mainly hyperactive and impulsive symptoms. Others have a combination of these behaviors. INATTENTIVE SYMPTOMS Doesn't pay attention to details or makes careless mistakes in schoolwork Has problems focusing during tasks or play Doesn't listen when spoken to directly Doesn't follow through on instructions and doesn't finish schoolwork or chores Has problems organizing tasks and activities Avoids or doesn't like tasks that require mental effort (such as schoolwork) Often loses things, such as homework or toys Is easily distracted Is often forgetful HYPERACTIVITY SYMPTOMS Fidgets or squirms in seat Leaves their seat when they should stay in their seat Runs about or climbs when they shouldn't be doing so Has problems playing or working quietly Is often "on the go," acts as if "driven by a motor" Talks all the time IMPULSIVITY SYMPTOMS Blurts out answers before questions have been completed Has problems awaiting their turn Interrupts or intrudes on others (butts into conversations or games) Many of the above findings are present in children as they grow. For these problems to be diagnosed as ADHD, they must be out of the normal range for a person's age and development.
Q95
Research assignment
Hi, I am a grade 12 student who is doing a research assignment on neurological disorders. Do you believe that there will ever be a bonafide cure for Multiple Sclerosis? If so, what kind of time frame would put on this cure?
multiple sclerosis
treatment
Q95-S1-A1
229
There is no known cure for MS at this time. But, there are treatments that may slow the disease. The goal of treatment is to control symptoms and help you maintain a normal quality of life. Medicines are often taken long-term. These include: - Medicines to slow the disease - Steroids to decrease the severity of attacks - Medicines to control symptoms such as muscle spasms, urinary problems, fatigue, or mood problems Medicines are more effective for the relapsing-remitting form than for other forms of MS. The following may also be helpful for people with MS: - Physical therapy, speech therapy, occupational therapy, and support groups - Assistive devices, such as wheelchairs, bed lifts, shower chairs, walkers, and wall bars - A planned exercise program early in the course of the disorder - A healthy lifestyle, with good nutrition and enough rest and relaxation - Avoiding fatigue, stress, temperature extremes, and illness - Changes in what you eat or drink if there are swallowing problems - Making changes around the home to prevent falls - Social workers or other counseling services to help you cope with the disorder and get assistance - Vitamin D or other supplements (talk to your provider first) - Complementary and alternative approaches, such as acupressure or cannabis, to help with muscle problems
Q95
Research assignment
Hi, I am a grade 12 student who is doing a research assignment on neurological disorders. Do you believe that there will ever be a bonafide cure for Multiple Sclerosis? If so, what kind of time frame would put on this cure?
multiple sclerosis
treatment
Q95-S1-A2
230
These resources address the diagnosis or management of multiple sclerosis: - Gene Review: Gene Review: Multiple Sclerosis Overview - Multiple Sclerosis Association of America: Treatments for MS - Multiple Sclerosis International Federation: About MS--Diagnosis - National Multiple Sclerosis Society: Diagnosing Tools These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
Q95
Research assignment
Hi, I am a grade 12 student who is doing a research assignment on neurological disorders. Do you believe that there will ever be a bonafide cure for Multiple Sclerosis? If so, what kind of time frame would put on this cure?
multiple sclerosis
treatment
Q95-S1-A3
231
There is as yet no cure for MS. Many patients do well with no therapy at all, especially since many medications have serious side effects and some carry significant risks.  However, three forms of beta interferon (Avonex, Betaseron, and Rebif) have now been approved by the Food and Drug Administration for treatment of relapsing-remitting MS. Beta interferon has been shown to reduce the number of exacerbations and may slow the progression of physical disability. When attacks do occur, they tend to be shorter and less severe.  The FDA also has approved a synthetic form of myelin basic protein, called copolymer I (Copaxone), for the treatment of relapsing-remitting MS. Copolymer I has few side effects, and studies indicate that the agent can reduce the relapse rate by almost one third.  Other FDA approved drugs to treat relapsing forms of MS in adults include teriflunomide and dimethyl fumarate.  An immunosuppressant treatment, Novantrone (mitoxantrone), is approved by the FDA for the treatment of advanced or chronic MS.  The FDA has also approved dalfampridine (Ampyra) to improve walking in individuals with MS. One monoclonal antibody, natalizumab (Tysabri), was shown in clinical trials to significantly reduce the frequency of attacks in people with relapsing forms of MS and was approved for marketing by the U.S. Food and Drug Administration (FDA) in 2004.  However, in 2005 the drug’s manufacturer voluntarily suspended marketing of the drug after several reports of significant adverse events.  In 2006, the FDA again approved sale of the drug for MS but under strict treatment guidelines involving infusion centers where patients can be monitored by specially trained physicians.  While steroids do not affect the course of MS over time, they can reduce the duration and severity of attacks in some patients.  Spasticity, which can occur either as a sustained stiffness caused by increased muscle tone or as spasms that come and go, is usually treated with muscle relaxants and tranquilizers such as baclofen, tizanidine, diazepam, clonazepam, and dantrolene. Physical therapy and exercise can help preserve remaining function, and patients may find that various aids -- such as foot braces, canes, and walkers -- can help them remain independent and mobile.  Avoiding excessive activity and avoiding heat are probably the most important measures patients can take to counter physiological fatigue.  If psychological symptoms of fatigue such as depression or apathy are evident, antidepressant medications may help.  Other drugs that may reduce fatigue in some, but not all, patients include amantadine (Symmetrel), pemoline (Cylert), and the still-experimental drug aminopyridine. Although improvement of optic symptoms usually occurs even without treatment, a short course of treatment with intravenous methylprednisolone (Solu-Medrol) followed by treatment with oral steroids is sometimes used.
Q96
null
Achondroplasia research. Hello, We are students from [LOCATION] and we are doing a biology project of genetic diseases. We chose Achondroplasia as our disease to research. We have a few question and we are hoping you could answer them. Our questions are, can you tell if your child will have Achondroplasia when you are pregnant? When do people usually come in when they think something isn't right with their child? what are the worse cases of Achondroplasia you've ever seen? Thank you in advance. sincerely, [NAME]
achondroplasia
diagnosis
Q96-S1-A1
232
Your doctor may diagnose your child with achondroplasia while you’re pregnant or after your infant is born. Diagnosis During Pregnancy Some characteristics of achondroplasia are detectable during an ultrasound. These include hydrocephalus, or an abnormally large head. If your doctor suspects achondroplasia, genetic tests may be ordered. These tests look for the defective FGFR3 gene in a sample of amniotic fluid, which is the fluid that surrounds the fetus in the womb. Diagnosis After Your Child Is Born Your doctor can diagnose your child by looking at his or her features. The doctor may also order X-rays to measure the length of your infant’s bones. This can help confirm a diagnosis. Blood tests may also be ordered to look for the defective FGFR3 gene.
Q96
null
Achondroplasia research. Hello, We are students from [LOCATION] and we are doing a biology project of genetic diseases. We chose Achondroplasia as our disease to research. We have a few question and we are hoping you could answer them. Our questions are, can you tell if your child will have Achondroplasia when you are pregnant? When do people usually come in when they think something isn't right with their child? what are the worse cases of Achondroplasia you've ever seen? Thank you in advance. sincerely, [NAME]
achondroplasia
prognosis
Q96-S2-A1
233
People with achondroplasia seldom reach 5 feet in height. Intelligence is in the normal range. Infants who receive the abnormal gene from both parents do not often live beyond a few months.
Q97
Subject
I'm calling because I would like to know more advice on crating Risperdoine medicine and gain experiences on the medication. And creating the medication
Risperdoine
information
Q97-S1-A1
234
Risperidone is used to treat the symptoms of schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions) in adults and teenagers 13 years of age and older. It is also used to treat episodes of mania (frenzied, abnormally excited, or irritated mood) or mixed episodes (symptoms of mania and depression that happen together) in adults and in teenagers and children 10 years of age and older with bipolar disorder (manic depressive disorder; a disease that causes episodes of depression, episodes of mania, and other abnormal moods). Risperidone is also used to treat behavior problems such as aggression, self-injury, and sudden mood changes in teenagers and children 5 to 16 years of age who have autism (a condition that causes repetitive behavior, difficulty interacting with others, and problems with communication). Risperidone is in a class of medications called atypical antipsychotics. It works by changing the activity of certain natural substances in the brain.
Q98
optic atrophy
Is optic atrophy ginetic and what cause it?
optic atrophy
cause
Q98-S1-A1
235
There are many causes of optic atrophy. The most common is poor blood flow. This is called ischemic optic neuropathy. The problem most often affects older adults. The optic nerve can also be damaged by shock, toxins, radiation, and trauma. Eye diseases, such as glaucoma, can also cause a form of optic nerve atrophy. The condition can also be caused by diseases of the brain and central nervous system. These may include: - Brain tumor - Cranial arteritis (sometimes called temporal arteritis) - Multiple sclerosis - Stroke There are also rare forms of hereditary optic nerve atrophy that affect children and young adults.
Q99
Essential Tremor information
What is the connection (if any) between Essential Tremor and Parkinsons and what is the best treatment for Essential Tremor?
essential tremor
information
Q99-S1-A1
236
Essential tremor is the most common movement disorder. It is characterized by involuntary and rhythmic shaking (tremor), especially in the hands, without any other signs or symptoms. It is distinguished from tremor that results from other disorders or known causes, such as tremors seen with Parkinson disease or head trauma. Most cases of essential tremor are hereditary. There are five forms of essential tremor that are based on different genetic causes. Several genes as well as lifestyle and environmental factors likely play a role in a person's risk of developing this complex condition. In mild cases, treatment may not be necessary. In cases where symptoms interfere with daily living, medications may help to relieve symptoms.
Q99
Essential Tremor information
What is the connection (if any) between Essential Tremor and Parkinsons and what is the best treatment for Essential Tremor?
essential tremor
information
Q99-S1-A2
237
Essential tremor is a movement disorder that causes involuntary, rhythmic shaking (tremor), especially in the hands. It is distinguished from tremor that results from other disorders or known causes, such as Parkinson disease or head trauma. Essential tremor usually occurs alone, without other neurological signs or symptoms. However, some experts think that essential tremor can include additional features, such as mild balance problems. Essential tremor usually occurs with movements and can occur during many different types of activities, such as eating, drinking, or writing. Essential tremor can also occur when the muscles are opposing gravity, such as when the hands are extended. It is usually not evident at rest. In addition to the hands and arms, muscles of the trunk, face, head, and neck may also exhibit tremor in this disorder; the legs and feet are less often involved. Head tremor may appear as a "yes-yes" or "no-no" movement while the affected individual is seated or standing. In some people with essential tremor, the tremor may affect the voice (vocal tremor). Essential tremor does not shorten the lifespan. However, it may interfere with fine motor skills such as using eating utensils, writing, shaving, or applying makeup, and in some cases these and other activities of daily living can be greatly impaired. Symptoms of essential tremor may be aggravated by emotional stress, anxiety, fatigue, hunger, caffeine, cigarette smoking, or temperature extremes. Essential tremor may appear at any age but is most common in the elderly. Some studies have suggested that people with essential tremor have a higher than average risk of developing neurological conditions including Parkinson disease or sensory problems such as hearing loss, especially in individuals whose tremor appears after age 65.
Q99
Essential Tremor information
What is the connection (if any) between Essential Tremor and Parkinsons and what is the best treatment for Essential Tremor?
essential tremor
treatment
Q99-S2-A1
238
Treatment may not be needed unless the tremors interfere with your daily activities or cause embarrassment. HOME CARE For tremors made worse by stress, try techniques that help you relax. For tremors of any cause, avoid caffeine and get enough sleep. For tremors caused or made worse by a medication, talk to your doctor about stopping the drug, reducing the dosage, or switching. Do not change or stop medications on your own. Severe tremors make it harder to do daily activities. You may need help with these activities. Things that can help include: - Buying clothes with Velcro fasteners, or using button hooks - Cooking or eating with utensils that have a larger handle - Using straws to drink - Wearing slip-on shoes and using shoehorns MEDICINES FOR TREMOR Medicines may help relieve symptoms. The most commonly used drugs include: - Propranolol, a beta blocker - Primidone, a drug used to treat seizures These drugs can have side effects. - Propranolol may cause fatigue, stuffy nose, or slow heartbeat, and it may make asthma worse. - Primidone may cause drowsiness, problems concentrating, nausea, and problems with walking, balance, and coordination. Other medications that may reduce tremors include: - Antiseizure drugs - Mild tranquilizers - Blood pressure drugs called calcium-channel blockers Botox injections given in the hand may be tried to reduce tremors. SURGERY In severe cases, surgery may be tried. This may include: - Focusing high-powered x-rays on a small area of the brain (stereotactic radiosurgery) - Implanting a stimulating device in the brain to signal the area that controls movement
Q99
Essential Tremor information
What is the connection (if any) between Essential Tremor and Parkinsons and what is the best treatment for Essential Tremor?
essential tremor
treatment
Q99-S2-A2
239
Treatment for essential tremor may not be necessary unless the tremors interfere with daily activities or cause embarrassment. Although there is no definitive cure for essential tremor, medicines may help relieve symptoms. How well medicines work depend on the individual patient. Two medications used to treat tremors include: Propranolol, a drug that blocks the action of stimulating substances called neurotransmitters, particularly those related to adrenaline Primidone, an antiseizure drug that also control the function of some neurotransmitters These drugs can have significant side effects. Eliminating tremor "triggers" such as caffeine and other stimulants from the diet is often recommended. Physical therapy may help to reduce tremor and improve coordination and muscle control for some patients. More details about the management of essential tremor can be accessed through the following web links: http://www.mayoclinic.com/print/essential-tremor/DS00367/METHOD=print&DSECTION=all http://emedicine.medscape.com/article/1150290-treatment
Q99
Essential Tremor information
What is the connection (if any) between Essential Tremor and Parkinsons and what is the best treatment for Essential Tremor?
essential tremor
treatment
Q99-S2-A3
240
These resources address the diagnosis or management of essential tremor: - Genetic Testing Registry: Hereditary essential tremor 1 - Johns Hopkins Movement Disorders Center - MedlinePlus Encyclopedia: Essential Tremor These resources from MedlinePlus offer information about the diagnosis and management of various health conditions: - Diagnostic Tests - Drug Therapy - Surgery and Rehabilitation - Genetic Counseling - Palliative Care
Q99
Essential Tremor information
What is the connection (if any) between Essential Tremor and Parkinsons and what is the best treatment for Essential Tremor?
essential tremor
treatment
Q99-S2-A4
241
There is no definitive cure for essential tremor. Symptomatic drug therapy may include propranolol or other beta blockers and primidone, an anticonvulsant drug. Eliminating tremor "triggers" such as caffeine and other stimulants from the diet is often recommended. Physical and occupational therapy may help to reduce tremor and improve coordination and muscle control for some individuals.  Deep brain stimulation uses a surgically implanted, battery-operated medical device called a neurostimulator to delivery electrical stimulation to targeted areas of the brain that control movement, temporarily blocking the nerve signals that cause tremor.  Other surgical intervention is effective but may have side effects.
Q100
dry mouth
My doctor does not know of a medication that can be used in the mouth for dry mouth. Through research, I think the medication is there, I just can't find the name of it for him to prescribe forme. Can you help me. I'm using the across the counter Biotene but would like something that works a little better.
dry mouth
treatment
Q100-S1-A1
242
Treatment for Dry Mouth Dry mouth treatment will depend on what is causing the problem. If you think you have dry mouth, see your dentist or physician. He or she can help to determine what is causing your dry mouth. If your dry mouth is caused by medicine, your physician might change your medicine or adjust the dosage. If your salivary glands are not working right but can still produce some saliva, your dentist or physician might give you a medicine that helps the glands work better. Your dentist or physician might also suggest that you use artificial saliva to keep your mouth wet. Do's and Don'ts Do's - Do drink water or sugarless drinks often. That will make chewing and swallowing easier when eating. - Do chew sugarless gum or suck on sugarless hard candy to stimulate saliva flow. - Do use a humidifier at night to promote moisture in the air while you sleep. Do drink water or sugarless drinks often. That will make chewing and swallowing easier when eating. Do chew sugarless gum or suck on sugarless hard candy to stimulate saliva flow. Do use a humidifier at night to promote moisture in the air while you sleep. Don’ts - Don't consume drinks with caffeine such as coffee, tea, and some sodas. Caffeine can dry out the mouth. - Don't use tobacco or alcohol. They dry out the mouth. Don't consume drinks with caffeine such as coffee, tea, and some sodas. Caffeine can dry out the mouth. Don't use tobacco or alcohol. They dry out the mouth. Gene Therapy Research for Salivary Gland Dysfunction Scientists at NIH’s National Institute of Dental and Craniofacial Research (NIDCR) are exploring the potential use of gene therapy to treat salivary gland dysfunction. The idea is to transfer additional or replacement genes into the salivary glands of people with Sjögren's syndrome and cancer patients whose salivary glands were damaged during radiation treatment. The hope is that these genes will increase the production of saliva and eliminate the chronic parched sensation that bothers people with dry mouth conditions. NIDCR recently completed a clinical study, a research study in humans, on gene therapy for radiation-damaged salivary glands. The study showed that gene therapy can be safely performed in salivary glands and that it has the potential to help head and neck cancer survivors with dry mouth. Read NIDCR’s news release to learn more about the study’s findings. Based on the promising results of this trial, similar clinical trials are planned in the near future. Research on Sjögren’s Syndrome and Other Diseases Affecting Salivary Glands NIDCR is also conducting clinical trials to study new approaches for improving salivary flow in patients with Sjogren’s syndrome. Such studies include testing the effectiveness of a monoclonal antibody as well as a corticosteroid to see whether either of these treatments helps improve salivary flow. Other studies are focused on learning how diseases such as diabetes, auto inflammatory diseases, and granulomatous diseases cause salivary gland dysfunction. Such studies could one day lead to better ways of preventing and treating salivary gland conditions. To stay abreast of any new studies on gene therapy and salivary gland function, visit ClinicalTrials.gov. ClinicalTrials.gov lists all federally and many privately funded clinical trials in the U.S. and around the world; the web site is updated frequently.
Q100
dry mouth
My doctor does not know of a medication that can be used in the mouth for dry mouth. Through research, I think the medication is there, I just can't find the name of it for him to prescribe forme. Can you help me. I'm using the across the counter Biotene but would like something that works a little better.
dry mouth
treatment
Q100-S1-A2
243
Dry mouth treatment will depend on what is causing the problem. If you think you have dry mouth, see your dentist or physician. He or she can help to determine what is causing your dry mouth. If your dry mouth is caused by medicine, your physician might change your medicine or adjust the dosage. If your salivary glands are not working right, but can still produce some saliva, your dentist or physician might give you a special medicine that helps the glands work better. He or she might suggest that you use artificial saliva to keep your mouth wet. (Watch the video to learn how dry mouth is treated. To enlarge the video, click the brackets in the lower right-hand corner. To reduce the video, press the Escape (Esc) button on your keyboard.)
Q101
lupus
Hi, I want to know about Lupus and its treatment. Best, [NAME]
lupus
information
Q101-S1-A1
244
Summary If you have lupus, your immune system attacks healthy cells and tissues by mistake. This can damage your joints, skin, blood vessels and organs. There are many kinds of lupus. The most common type, systemic lupus erythematosus, affects many parts of the body. Discoid lupus causes a rash that doesn't go away. Subacute cutaneous lupus causes sores after being out in the sun. Another type can be caused by medication. Neonatal lupus, which is rare, affects newborns. Anyone can get lupus, but women are most at risk. Lupus is also more common in African American, Hispanic, Asian and Native American women. The cause of lupus is not known. Lupus has many symptoms. Some common ones are - Joint pain or swelling - Muscle pain - Fever with no known cause - Fatigue - Red rashes, often on the face (also called the "butterfly rash") There is no one test to diagnose lupus, and it may take months or years to make the diagnosis. There is no cure for lupus, but medicines and lifestyle changes can help control it. NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
Q101
lupus
Hi, I want to know about Lupus and its treatment. Best, [NAME]
lupus
Treatment
Q101-S2-A1
245
You may need special kinds of doctors to treat the many symptoms of lupus. …. You should report new symptoms to your doctor right away so that treatment can be changed if needed. The goals of the treatment plan are to: Prevent flares Treat flares when they occur Reduce organ damage and other problems. Treatments may include drugs to: Reduce swelling and pain Prevent or reduce flares Help the immune system Reduce or prevent damage to joints Balance the hormones. In addition to medications for lupus itself, sometimes other medications are needed for problems related to lupus such as high cholesterol, high blood pressure, or infection. Alternative treatments are those that are not part of standard treatment. No research shows that this kind of treatment works for people with lupus. You should talk to your doctor about alternative treatments.
Q101
lupus
Hi, I want to know about Lupus and its treatment. Best, [NAME]
lupus
Treatment
Q101-S2-A2
246
There is no cure for lupus, but medicines and lifestyle changes can help control it. People with lupus often need to see different doctors. You will have a primary care doctor and a rheumatologist (a doctor who specializes in the diseases of joints and muscles). Which other specialists you see depends on how lupus affects your body. For example, if lupus damages your heart or blood vessels, you would see a cardiologist.
Q102
varicella shingles
How can I determine whether or not I've had chicken pox. If there is a test for it, what are the results of the tests I need to know that will tell me whether or not I have had chicken pox? I want to know this to determine if I should have shingles vaccine (Zostavax) Thank you.
chicken pox
diagnosis
Q102-S1-A1
247
Your health care provider can most often diagnose chickenpox by looking at the rash and asking questions about the person's medical history. Small blisters on the scalp confirm the diagnosis in most cases. Lab tests can help confirm the diagnosis, if needed.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
cause
Q103-S1-A1
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Some cases of chronic myelomonocytic leukemia (CMML) are linked to cancer treatment, but in most cases the cause is unknown. Over the past few years, scientists have made progress in understanding how certain changes in the DNA of bone marrow cells may cause CMML to develop. DNA is the chemical that carries the instructions for nearly everything our cells do. We usually look like our parents because they are the source of our DNA. However, DNA affects more than the way we look. Some genes (parts of DNA) control a cell’s growth and division process. Genes that promote cell division are called oncogenes. Other genes called tumor suppressor genes can slow down cell division or even make cells die at an appropriate time. Cancers can be caused by DNA mutations (gene defects) that turn on oncogenes or turn off tumor suppressor genes. In some diseases, mutations may be passed down from a parent. Inherited mutations do not seem to cause CMML. Instead, the mutations are acquired during the person’s lifetime. Exposure to radiation or cancer-causing chemicals can cause mutations that lead to CMML. Sometimes these gene changes occur for no apparent reason. Every time a cell prepares to divide into 2 new cells, it must copy its DNA. This process is not perfect, and copying errors can occur. Fortunately, cells have repair enzymes that read and fix DNA. However, some errors may slip past, especially if the cells are growing rapidly. Human DNA is packaged in 23 pairs of chromosomes. In up to half of patients, CMML cells contain altered chromosomes. Sometimes part of one chromosome attaches to a different chromosome. This is called a translocation. Like mutations, translocations can turn on oncogenes or turn off tumor suppressor genes. Acquired translocations are seen in some cases of CMML. Another chromosome abnormality that can be seen in CMML is called a deletion. This involves the loss of all or part of a chromosome. Another type of chromosome abnormality is called a duplication. This is when there is an extra copy of all or part of a chromosome.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
prognosis
Q103-S2-A1
249
People with acute myelogenous leukemia (AML) may have questions about their prognosis and survival. Prognosis and survival depend on many factors. Only a doctor familiar with a person’s medical history, type of cancer, stage, characteristics of the cancer, treatments chosen and response to treatment can put all of this information together with survival statistics to arrive at a prognosis. A prognosis is the doctor’s best estimate of how cancer will affect a person and how it will respond to treatment. A prognostic factor is an aspect of the cancer or a characteristic of the person that the doctor will consider when making a prognosis. A predictive factor influences how a cancer will respond to a certain treatment. Prognostic and predictive factors are often discussed together and they both play a part in deciding on a treatment plan and a prognosis.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
information
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Leukemia is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. Leukemia Starts in Bone Marrow Types of blood cells made by the bone marrow and a description of their functions. - Click to enlarge in new window. Click for more information Leukemia usually begins in the bone marrow, the soft material in the center of most bones where blood cells are formed. The bone marrow makes three types of blood cells, and each type has a special function. White blood cells fight infection and disease. Red blood cells carry oxygen throughout the body. Platelets help control bleeding by forming blood clots. In people with leukemia, the bone marrow produces abnormal white blood cells, called leukemia cells. At first, leukemia cells function almost normally. But over time, as more leukemia cells are produced, they may crowd out the healthy white blood cells, red blood cells, and platelets. This makes it difficult for the blood to carry out its normal functions. There are four common types of adult leukemia. Two are chronic, meaning they get worse over a longer period of time. The other two are acute, meaning they get worse quickly. chronic lymphocytic leukemia chronic myeloid leukemia acute myeloid leukemia acute lymphocytic leukemia
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
inheritance
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251
Sometimes people inherit DNA mutations from a parent that greatly increase their risk of getting certain types of cancer. But inherited mutations rarely cause CLL. DNA changes related to CLL usually occur during the person's lifetime, rather than having been inherited before birth.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
diagnosis
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Diagnosing Leukemia: Physical Exam, Blood Tests, Biopsy To find the cause of leukemia symptoms, the doctor will ask about medical history and conduct a physical exam. During the exam, the doctor will check for signs of disease such as lumps, swelling in the lymph nodes, spleen, and liver, or anything else that seems unusual. The doctor will need to do blood tests that check the levels and types of blood cells and look for changes in the shape of blood cells. The doctor also may look at certain factors in the blood to see if leukemia has affected other organs such as the liver or kidneys. Pathologist examining samples under a microscope. - Click to enlarge in new window. Click for more information Even if blood tests suggest leukemia, the doctor may look for signs of leukemia in the bone marrow by doing a biopsy before making a diagnosis. A biopsy is a procedure where a small amount of bone marrow is removed from a bone. A pathologist examines the sample under a microscope to look for abnormal cells. There are two ways the doctor can obtain bone marrow. In a bone marrow aspiration, marrow is collected by inserting a needle into the hipbone or another large bone and removing a small amount of bone marrow. A bone marrow biopsy is performed with a larger needle and removes bone marrow and a small piece of bone. If Leukemia Cells Are Found If leukemia cells are found in the bone marrow sample, the doctor may perform more tests to determine if the disease has spread to other parts of the body. The doctor may collect a sample of the fluid around the brain and spinal cord by performing a spinal tap and checking for leukemia cells or other signs of problems. Computed tomography (CT) scans, and ultrasounds are tests used to determine if leukemia has spread from the bone marrow. These tests produce pictures of the inside of the body. With these tests, the doctor looks for abnormalities such as enlarged organs or signs of infection.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
treatment
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There are many treatment options for people with leukemia. The choice of treatment depends on your age and general health, the type of leukemia you have, whether or not it has spread outside the bone marrow, and other factors. If tests show that you have leukemia, you should talk with your doctor and make treatment decisions as soon as possible, although many patients with chronic lymphocytic leukemia do not require treatment for many years. Working With a Team of Specialists A team of specialists often treats people with leukemia. The team will keep the primary doctor informed about the patient's progress. The team may include a hematologist who is a specialist in blood and blood-forming tissues, a medical oncologist who is a specialist in cancer treatment, and a radiation oncologist who is a specialist in radiation therapy. Before starting treatment, you may want another doctor to review the diagnosis and treatment plan. Some insurance companies require a second opinion. Others may pay for a second opinion if you or your doctor requests it. Clinical Trials for Leukemia Some leukemia patients take part in studies of new treatments. These studies, called clinical trials, are designed to find out whether a new treatment is safe and effective and better than current treatments. Talk to your doctor if you are interested in taking part in a clinical trial. The U.S. National Institutes of Health, through its National Library of Medicine and other Institutes, maintains a database of clinical trials at ClinicalTrials.gov. Click here to search for current clinical trials on leukemia.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
treatment
Q103-S6-A2
254
Unlike other types of cancer, leukemia isn't a tumor that your doctor can surgically remove. Leukemia cells are produced in the bone marrow and travel throughout the body. The Goal of Treatment The goal of treatment for leukemia is to destroy the leukemia cells and allow normal cells to form in the bone marrow. Depending on the type and extent of the disease, patients may have chemotherapy, biological therapy, radiation therapy, or stem cell transplantation. Some patients receive a combination of treatments. Treatment depends on a number of factors, including the type of leukemia, the patient's age and general health, whether leukemia cells are present in the fluid around the brain or spinal cord, and whether the leukemia has been treated before. It also may depend on certain features of the leukemia cells and the patient's symptoms. Acute Leukemia or Chronic Leukemia? If a person has acute leukemia, they will need treatment right away. The purpose of treatment is to stop the rapid growth of leukemia cells and to bring about remission, meaning the cancer is under control. In many cases, a person will continue treatment after signs and symptoms disappear to prevent the disease from coming back. Some people with acute leukemia can be cured. Learn more about treatments for acute myeloid leukemia. Learn more about treatments for chronic lymphocytic leukemia. Chronic leukemia may not need to be treated until symptoms appear. Treatment can often control the disease and its symptoms. Types of Treatments Some, but not all, forms of treatment for leukemia include - chemotherapy - biological therapy - radiation therapy. chemotherapy biological therapy radiation therapy. Chemotherapy Chemotherapy uses drugs to kill cancer cells. This a common treatment for some types of leukemia. Chemotherapy may be taken by mouth in pill form, by injection directly into a vein, or through a catheter. If leukemia cells are found in the fluid around the brain or spinal cord, the doctor may inject drugs directly into the fluid to ensure that the drugs reach the leukemia cells in the brain. Biological Therapy Biological therapy uses special substances that improve the body's natural defenses against cancer. Some patients with chronic lymphocytic leukemia receive monoclonal antibodies, which are man-made proteins that can identify leukemia cells. Monoclonal antibodies bind to the cells and assist the body in killing them. Although monoclonal antibodies are being used to treat leukemia, researchers are studying more innovative ways to use them in treatment. Some antibodies are used alone to try to prompt the immune system to attack leukemia cells. Other antibodies are attached to substances that can deliver poison to cancer cells. These modified antibodies, called immunotoxins, deliver the toxins directly to the cancer cells. Lately, precision medicine trials have shown evidence that single targeted therapies taken in pill form can prolong survival. Radiation Therapy Radiation therapy uses high-energy X-rays to destroy cancer cells. A machine outside the body directs high-energy beams at the spleen, the brain, or other parts of the body where leukemia cells have collected. Radiation therapy is used primarily to control disease in bones that are at risk of fracture or at sites that are causing pain.
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Project. Hi my name is [NAME] and I'm doing a school project about leukemia and I was wondering if you can anwser some of my questions please.1. What cause leukemia cancer?2. Can you survive leukemia?3. How does leukemia affect your body?4. Is leukemia inherited?5. What is advanced leukemia?6. How long can someone with leukemia expect to live?7. Can you tell if you have leukemia?8. What treatments do you need to take?9. What are the signs of leukemia?10. What is the difference between AML and CML ?
leukemia
treatment
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Treatment depends on a number of factors, including the type of leukemia, the patient's age and general health, where leukemia cells have collected in the body, and whether the leukemia has been treated before. Certain features of the leukemia cells and the patient's symptoms also may determine treatment options.