title
stringlengths
3
1.99k
abstract
stringlengths
1
512
pmid
stringlengths
6
8
abstract embedding
sequence
title embedding
sequence
[Frenulectomy for ankyloglossia].
nan
2635041
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[Asymmetrical partial crown preparation].
nan
2635042
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[Canal obturation].
nan
2635043
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[Frenulectomy: indications and limits].
nan
2635044
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[Gold foil in Class V restorations].
nan
2635045
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[Self-threading endosseous screw].
nan
2635046
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[Regional section of the apex and its curettage].
nan
2635047
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[Reliability of retrograde apical seal].
nan
2635048
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[SEM evaluation of a new posterior composite].
nan
2635049
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[Diagnostic value of five observers in evaluating systematic orthopanoramic radiographs].
nan
2635050
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[Hepatitis B--an occupational hazard preventable by immunization].
nan
2635051
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[Caries epidemiology and the SCOR-system].
nan
2635052
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Tandem neurofibromas associated with cord compression.
nan
2635053
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Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain.
The expression of basic FGF mRNA; while virtually absent in peripheral tissues; appears to be constitutively expressed in the central nervous system. As such; while it is difficult to detect any mRNA encoding basic FGF in the heart; lung; kidneys; ovaries; liver; or pituitary of rats; the levels are easily detected in brain. A regional analysis of the expression of basic FGF mRNA in brain reveals that it is widely distributed in the cortex (frontal; parietal; and occipital); the hippocampus; hypothalamus; a
2635054
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-0.0044181263, -0.010132589, -0.0010441792, -0.026667494, 0.0055954116, 0.06989635, -0.037752494, 0.06254163, 0.056932986, -0.012202759, 0.002852271, 0.0039253864, 0.013327133, 0.06270036, -0.037435025, -0.016984655, 0.023294374, -0.021971582, -0.07254194, 0.0066867154, 0.0014997158, -0.29291916, 0.0092926165, 0.064816825, -0.0402658, 0.037964143, -0.015079834, 0.032461327, -0.020873664, -0.012196146, 0.053943474, 0.05846742, 0.0023959076, 0.07021382, -0.0018882861, -0.048652302, 0.047514703, 0.07703943, -0.029127888, 0.023876403, -0.06640418, 0.014352297, 0.017672505, 0.12836377, 0.0034921719, -0.041191753, -0.07550499, -0.021680567, -0.007784633, 0.01287077, 0.01611161, 0.03981605, 0.031112077, 0.011455382, -0.0039253864, -0.0006547822, 0.025318246, -0.04891686, 0.004662843, 0.024696534, -0.05587475, -0.024365835, -0.0100399945, -0.0927542, -0.029286623, 0.023347285, -0.10222539, -0.007883843, 0.0115347495, -0.022050949, -0.021759935, -0.028678138, 0.044445824, 0.03624451, -0.0334931, -0.018082572, -0.010125976, 0.070002176, -0.08714556, 0.037726037, -0.027619906, -0.03288462, -0.016667183, 0.008604764, 0.107410744, 0.04484266 ]
Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain.
nd pons. Only a few loci of basic FGF synthesis are detected by in situ hybridization and include layers 2 and 6 of the medial (cingulate) cortex; the indusium griseum; fasciola cinereum; and field CA2 of the hippocampus. The identification of specific cell populations in the brain; and particularly in the hippocampus; that synthesize basic FGF supports the notion that this potent neurotrophic factor is involved in normal CNS function and that the presence (or absence) of its expression may be linked to the
2635054
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0.024295285, -0.0047237147, 0.06066523, -0.06602585, 0.02551602, 0.036383215, 0.022570333, -0.008863599, 0.005665804, 0.08316922, -0.003804846 ]
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-0.058488846, 0.024281895, -0.004753546, 0.060611855, -0.066025525, 0.025436278, 0.036276884, 0.022596758, -0.008817114, 0.0056193345, 0.08311573, -0.0037484346 ]
Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain.
pathogenesis of the neurogenerative diseases characterizing these various loci. The significance of these findings with respect to the regulation of basic FGF expression in peripheral tissue and the central nervous system is discussed.
2635054
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Interleukin 3 mediates interleukin 6 production in murine interleukin 3-dependent hemopoietic cells.
A series of murine interleukin 3 (IL-3)-dependent hemopoietic cell lines was studied for the capacity to produce interleukin 6 (IL-6) in vitro. These included a bone marrow-derived mast cell line (L138.8A) and several early myeloid cell lines described in the literature (DA-1; DA-3; NFS-60; NFS-78; FDC-P1; FDC-P2; FDC-PmixA4; and 32Dcl.23). All of these cell lines produced growth factor activity for IL-6-dependent hybridoma cells (7TD1); which was completely neutralized by the monoclonal anti-IL-6-antibody
2635055
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Interleukin 3 mediates interleukin 6 production in murine interleukin 3-dependent hemopoietic cells.
6B4. IL-6 expression was also evident at the mRNA level using a murine IL-6-specific cDNA probe. In 32Dcl.23 cells (2 x 10(5)/ml) stimulated for 24 hr with serial dilutions of purified murine IL-3; a positive correlation was found between the IL-3 dose and the amount of IL-6 measured in the conditioned media. At 24 hr this correlation was not evident at the mRNA level. However; prolonged exposure of 32Dcl.23 cells (up to 72 hr) to either a high (60 U/ml) or a low IL-3 concentration (1 U/ml) revealed a time-
2635055
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Interleukin 3 mediates interleukin 6 production in murine interleukin 3-dependent hemopoietic cells.
dependent increase and decrease; respectively; of IL-6 mRNA levels. At both IL-3 concentrations 32Dcl.23 cells remained in a fully viable and proliferative state. The influence of IL-3 on IL-6 release could be specifically counteracted by anti-IL-3-antiserum. IL-6 added alone or in concert with IL-3 did not stimulate 32Dcl.23 proliferation.(ABSTRACT TRUNCATED AT 250 WORDS)
2635055
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0.040606253, -0.07308063, 0.03669976, 0.04265251, 0.0032304958, -0.049269628, -0.047489118, 0.06824402, -0.008676663 ]
[Influence on de- and remineralization of dental enamel by toothbrushing with a dental salt].
In the study in question; tests were made to determine whether a dental salt; with or without the addition of fluoride; can improve the remineralization effect of the saliva. The experiments were performed in vitro by applying a method in which the dental enamel was softened and rehardened several times within a short period. The Knoop hardness of the enamel surface was used to determine the degree of de- and remineralization. The results clearly confirm the remineralization-promoting effect of the fluoride
2635057
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0.0960175, 0.021232076, 0.023084719, -0.033934, -0.048888423, 0.035373464, 0.05843153, 0.029988809, -0.005924456, 0.010056247, -0.0045049856, 0.06125714, 0.053526692 ]
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-0.31518903, -0.040651496, -0.006344299, 0.025283897, 0.13765529, -0.06035081, 0.08476836, -0.010329478, -0.0039551905, -0.08983314, -0.01575412, 0.027323136, 0.005757851, 0.00090299634, 0.05597911, -0.033667434, 0.052513737, 0.0013245057, -0.019352777, -0.0078037544, 0.038492303, 0.012315404, 0.009003307, 0.028176151, 0.020885538, 0.0026506775, 0.13680229, -0.014847793, -0.055445973, 0.049688123, 0.0458229, 0.063976124, 0.022364987, -0.12699261, -0.050514482, -0.0032721122, 0.043530423, 0.016180629, -0.08977983, -0.016380554, -0.008650105, 0.0034387168, 0.048035406, 0.0045116497, -0.050887674, -0.012981822, 0.031401616, 0.010775979, -0.0002149198, -0.00006419479, 0.028735943, 0.022191718, 0.028895883, 0.009969613, -0.0055479296, -0.040011734, -0.015207658, 0.015807435, -0.0745855, -0.054033168, -0.015101031, 0.03230794, 0.041317914, -0.081676185, -0.030148748, 0.043743674, 0.014861121, -0.05581917, 0.02452418, 0.06045744, -0.031374957, 0.12091488, -0.030735197, 0.048381943, -0.012335396, 0.048142035, -0.04070481, -0.070213795, -0.043397136, -0.0033904014, -0.015847418, -0.09361839, 0.050221257, 0.005981101, 0.028229466, 0.016633792, -0.016847046, -0.056245677, -0.020818897, 0.031694837, -0.021911822, -0.025577122, -0.020019196, -0.023004748, 0.038518958, 0.0032904388, -0.24972014, -0.011795598, 0.05006132, 0.0016052342, -0.045636304, 0.024230957, 0.05741857, -0.0033504162, -0.040811434, 0.01344165, 0.00795703, 0.013275046, 0.017806688, 0.010162874, -0.0049248287, -0.004948153, 0.023844434, -0.04078478, 0.026456794, -0.070000544, 0.028949196, -0.023937734, 0.15620837, -0.005108094, -0.021498643, 0.0049881386, 0.028522689, -0.014967747, 0.005751187, 0.0040618177, -0.0010212855, -0.034733705, -0.018553076, 0.017553449, -0.0020592315, 0.0789572, -0.059071288, -0.03145493, -0.004451672, 0.0189396, -0.00055770855, 0.0040318286, -0.056672182, -0.005044784, 0.07879726, -0.12549983, 0.009416486, -0.065948725, 0.037426032, 0.018646374, -0.04291732, -0.055712543, 0.0960175, 0.021232076, 0.023084719, -0.033934, -0.048888423, 0.035373464, 0.05843153, 0.029988809, -0.005924456, 0.010056247, -0.0045049856, 0.06125714, 0.053526692 ]
[Influence on de- and remineralization of dental enamel by toothbrushing with a dental salt].
added to the dental salt.
2635057
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Effects of interleukin-6 on the growth of normal and transformed rat liver cells in culture.
Recombinant human interleukin-6 produced a dose-dependent inhibition of DNA synthesis in both growing and mitogen-stimulated cultures of normal rat liver epithelial cells and also in primary rat hepatocytes. A significant inhibition of DNA synthesis (P less than 0.001) was obtained with 1 ng/ml (10 Units/ml) interleukin-6 in normal rat liver epithelial cells. The ID50 for inhibition of DNA synthesis in primary rat hepatocytes was 1 ng/ml. In contrast to the effects of transforming growth factor beta (Type I
2635056
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Effects of interleukin-6 on the growth of normal and transformed rat liver cells in culture.
); where an almost complete inhibition of DNA synthesis could be achieved with either cell type; the maximal inhibition observed with interleukin-6 for both of these cell types was about 45%. Thus distinct mechanisms are involved in the inhibition of liver cell growth by these growth modulators. Transformed liver-derived cell lines were relatively resistant to the growth inhibitory effects of both interleukin-6 and TGF-beta 1 compared with the normal cells. However; human Hep G2 cells; which were completely
2635056
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Effects of interleukin-6 on the growth of normal and transformed rat liver cells in culture.
resistant to the growth inhibitory effects of TGF-beta 1; were moderately inhibited by interleukin-6; indicating that the mechanisms responsible for the acquired resistance to growth inhibition is different for these growth inhibitors. The ability of interleukin-6 to function as a growth inhibitor in vitro was confirmed using normal rat liver epithelial cells. Interleukin-6 at a concentration of 10 ng/ml produced a significant decrease (P less than 0.05) in the proliferation of these cells. These data demo
2635056
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-0.047368117, -0.08428699, 0.015247362, 0.0051946323, -0.049767178, 0.02529676, -0.031640943, 0.0006884804, 0.03158763, 0.01709997, -0.007776954, 0.04091731, 0.013408083, 0.013954535, 0.0064941235, -0.0020541956, -0.054165453, 0.031667598, -0.003528618, -0.24438429, -0.0071105487, 0.07010588, 0.019485703, -0.007850259, 0.040304217, 0.073038064, -0.0014760885, -0.051553145, 0.017713062, 0.023910636, -0.0016651812, 0.09020467, 0.052459456, 0.013328114, -0.04739477, 0.022657793, -0.013554691, -0.010722468, -0.019752264, 0.05672445, -0.014594285, 0.09340342, -0.028282257, -0.045848712, 0.01519405, -0.011522154, -0.014434347, -0.052539423, 0.043636244, -0.015793815, 0.009676211, 0.073677815, -0.035159566, 0.0060442993, 0.053312454, 0.027455915, 0.034439847, -0.04147709, 0.0017093306, -0.026043134, 0.020671904, -0.06706707, 0.0053112535, 0.060936134, -0.06440145, 0.00065224455, -0.001994219, -0.036225814, 0.011362217, -0.032014128, -0.011422194, 0.051606458, -0.0063775023, -0.017739719, -0.050966706, 0.046595085, -0.025643291, 0.06520113, 0.021231685, 0.029241882, -0.024776964, -0.040890653, 0.1001741, 0.04926071 ]
Effects of interleukin-6 on the growth of normal and transformed rat liver cells in culture.
nstrate that interleukin-6 may have the capability of functioning as a growth regulatory polypeptide for liver cells in vivo.(ABSTRACT TRUNCATED AT 250 WORDS)
2635056
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[Plaque--gingivitis--periodontitis. (2) Microbiology and pathogenesis of periodontitis].
In a survey; current conceptions regarding the origin of gingivitis and periodontitis; as well as their clinical picture; are described. After the build-up of the bacterial plaque in several phases to form a periodontal pathogenic plaque; following a short; acute stage; a chronic gingivitis soon establishes itself in the neighbouring soft gingival tissue; from which; not inevitably; however; a periodontitis can develop after some years; the osseous parts now also being involved in the periodontal destructio
2635058
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[Plaque--gingivitis--periodontitis. (2) Microbiology and pathogenesis of periodontitis].
n; in which the polymorphonuclear neutrophilic granulocytes appear to have a major share. Depending on the age of the patient; progress of the disease; and the composition of the subgingival plaque; endeavours are made to classify the periodontal diseases into four subgroups. In recent years; however; doubt has increased as to whether gingivitis and even the periodontitides can be considered as comprising a single disease. However; this does not affect therapeutic concepts developed on the basis of opinions
2635058
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[Plaque--gingivitis--periodontitis. (2) Microbiology and pathogenesis of periodontitis].
to date and which; as a rule; are successful; so that; for the time being; there is no reason for a change in this sphere.
2635058
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[Steglitz ten-year pre-school dental health program].
The prophylactic dental program for 5 to 6 year old pre-school children; which has been conducted in Berlin-Steglitz for the past 10 years; is described; in which not only questions and exercises in respect of oral hygiene and healthy nutrition are included; but also comprehensive demonstrations of what happens in the dental practice. The pre-school program is always in great demand. Children show more willingness to be treated.
2635059
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0.013575491, 0.052539088, -0.003966474, 0.03352138, 0.012547146, 0.026897235, -0.015839186, -0.03571162, 0.12083723, 0.05972415 ]
[Toothbrushing before or after mealtime].
nan
2635060
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0.022444457, -0.0403713, -0.052070096, -0.016764795, -0.04324377, -0.04507171, -0.0046220697, -0.008800212, 0.029038088 ]
[Distribution of oral hygiene aids on air flights].
The question as to which dental care aids airlines offered their passengers to assist their oral hygiene during their flight was to be answered with the assistance of a questionnaire. 56 replies showed large differences existed varying with the different airlines; the flight time and the passenger class. Toothpicks were offered by almost 90% of the companies. Toothbrushes; toothpaste and mouth hygiene sets were distributed more rarely; primarily in the higher passenger classes and on long haul flights. The
2635061
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[Distribution of oral hygiene aids on air flights].
use of the aids was estimated by 24 companies as frequent; 12 estimated that the distributed aids were rarely used or mainly had a souvenir value.
2635061
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[Scanning electron microscopic study of penetrability of sealants in relation to fissure morphology of permanent premolars in humans].
In the work presented here; the morphological types of the fissure system in permanent human premolars are established; their average depth and width as well as the penetration capacity of fissure in relation to the morphological type of the fissure established (V; U; Y1; Y2). The largest average fissure depth was yielded by the Y2-configuration; the lowest by the V-type. The largest average entrance width was shown by the V-type; the lowest by the Y2-type. A total of 71% of the cases showed a complete fill
2635062
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[Scanning electron microscopic study of penetrability of sealants in relation to fissure morphology of permanent premolars in humans].
ing of the fissure pattern by the sealing matter. All types of V- and U-fissures were totally filled up. With the Y1-type there is a total filling up in 60.7-88.1% of the cases; with the Y1 type in 23.6-57.6% of the cases to be expected. The penetration capacity of the sealer is in a certain correlation to the width of the fissure entrance and the fissure depth.
2635062
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0.06574021, 0.0029853252, 0.016435053, 0.009664555, 0.038552016, 0.010461085, 0.009458785, -0.013222386, 0.061014142, 0.09388425 ]
[Dried fruit as sugar substitute?].
Alternative foodstuffs restrict the usage of household sugar and instead recommend sweet honey or dried fruits; in popular informative magazines raisins and dried fruit are even described as "healthy snacks". In this study; with the help of sugar clearance and lactic acid measurements; the cariogenic potential of dried fruits is to be better estimated. The results clearly show that the alternative recommendations do not promote healthy teeth. The cariogenic potential of the named foodstuffs is comparable to
2635063
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[Dried fruit as sugar substitute?].
sucrose containing products.
2635063
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0.014783359, -0.053089265, -0.06823894, -0.016261695, -0.06290123, 0.00594605, -0.010721206, -0.022816086, -0.052042656, 0.043931432, -0.03631735 ]
[Effect of Xylitol chewing gum on total saliva and dental plaque in caries-active persons].
Total saliva and toothplaque values were investigated with caries active persons during the use of xylital containing chewing gum. 20 caries active individuals (DMFS 54.4) chewed 5 xylitol chewing gums per day over a period of 4 weeks. The most important result was the reduction in lacto-bacilli values. This may have occurred because of the inability of acid forming bacteria to metabolise xylitol.
2635064
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Normally cycling and latch bridges in venous smooth muscle.
We have studied the mechanical properties of the crossbridges of canine saphenous venous smooth muscle during activation by electrical stimulation. A length-tension relationship study showed that at optimal length (1o) the maximum isometric tension (Po) developed was 87.9 mN/mm2. Resting tension at 1o was only 6% Po; which indicates a very compliant muscle. Active tension was observed at muscle lengths greater than 0.3 1o. The maximum shortening capacity was 0.65 1o. Force-velocity and series elastic charac
2635065
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Normally cycling and latch bridges in venous smooth muscle.
teristics were determined by the method of quick release to a set of load clamps applied during the course of an isometric contraction. The data were fitted by the hyperbolic Hill equation. Estimated maximum shortening velocity at zero load (Vo) an index of the crossbridge cycling rate) was 0.26 1o/s which was attained early in the contraction (5 s after the stimulation). A 11.9% decline in Vo was observed at the plateau of the contraction which occurred at 15 s. The stress (sigma)-strain (epsilon) curve fo
2635065
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-0.0022424008, -0.017038936, -0.01934257, 0.023234913, -0.036037285, 0.011306334, -0.03834092, -0.020904802, 0.01191534, 0.044881117 ]
Normally cycling and latch bridges in venous smooth muscle.
r the series elastic component could be approximated by the equation sigma = B[exp(A epsilon)-1]; where A = 76.51 (1/1o); B = 2.89 mN/mm2 at 5 s and A = 61.49 (1/1o); B = 1.85 mN/mm2 at 15 s. Like other smooth muscles; in general; saphenous vein develops considerable isometric tension and has a high shortening capacity but a low shortening velocity. The reduction in shortening velocity that occurs after 5 s in an isometric contraction is probably due to the development of so-called latch bridges.
2635065
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Caffeine-induced contraction in arteries from stroke-prone spontaneously hypertensive rats.
Differences in caffeine-induced contraction in smooth muscle of resistance vessels from stroke-prone spontaneously hypertensive rats (SHRSP) and Wistar Kyoto rats (WKY) were investigated by using mesenteric artery preparations. The contraction induced by caffeine (10 mM) was greater in SHRSP preparations; both in the presence and absence of Ca (10 min after Ca removal). Caffeine-induced contraction was gradually decreased by the removal of extracellular Ca. No significant difference was observed in the time
2635066
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Caffeine-induced contraction in arteries from stroke-prone spontaneously hypertensive rats.
course of the decay of the contraction between SHRSP and WKY preparations; and the contraction disappeared when the time in Ca-free solution exceeded 80 min. The contraction induced by high-K-Tyrode's solution was completely abolished within 10 min after Ca removal; both in SHRSP and WKY preparations. Caffeine-induced contraction could be blocked by procaine or ryanodine. The results suggest that caffeine induces contraction by releasing Ca from sarcoplasmic reticulum; and that the release of Ca is greater
2635066
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Caffeine-induced contraction in arteries from stroke-prone spontaneously hypertensive rats.
in SHRSP vascular smooth muscle. It is also suggested that sarcoplasmic reticulum is leaky for stored Ca when extracellular Ca is removed; and that the rate of leakage does not differ between smooth muscle cells of SHRSP and WKY mesenteric arteries.
2635066
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[The importance of analytical chemistry in the study of biodistribution and pharmacokinetics of drugs].
nan
2635068
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Myogenic responses are independent of the endothelium in rat pressurized posterior cerebral arteries.
nan
2635067
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[Pharmacokinetics of salicylate in rabbits with acute renal damage].
Changes in the pharmacokinetics and metabolism of sodium salicylate were studied in rabbits with acute renal damage induced by intravenous administration of uranyl nitrate in the dose of 0.2 mg/kg. In the pathological group there occurs a marked decrease in elimination characteristics; the total plasma clearance of salicylate linearly decreasing with a decrease in the value of glomerular filtration rate. The plasma levels of creatinine and urea are suitable indices for the estimation of the changes in the p
2635069
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[Pharmacokinetics of salicylate in rabbits with acute renal damage].
lasma binding of salicylate. An increase in the fraction of free salicylate in the plasma of rabbits with acute impairment of the kidney results in a not very conclusive increase in the size of distributional volumes. In the control group mainly the unchanged drug is excreted into urine; whereas in rabbits with acute renal damage salicylate metabolites represent the majority of the eliminated amount.
2635069
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[Distribution of 14C-pethidine in the blood of certain species].
Binding of 14C-pethidine to erythrocytes of some species; particularly human; rat and rabbit; was examined in two different concentrations. This binding was investigated by direct measurement of the relative representation in erythrocytes; plasma proteins and the free fraction in blood. In the case of human erythrocytes the relative representation was 33%; in the rat ones 44%; and in the rabbit ones 54%. The fraction bound to plasma proteins was 45% in man; 29% in rats; and 27% in rabbits. The portion of th
2635070
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[Distribution of 14C-pethidine in the blood of certain species].
e free fraction was 22% in man; 27% in rats; and 19% in rabbits. The ratio of the concentrations of the fraction bound to erythrocytes and the fraction free in the blood was 1.72 in man; 2.09 in rats; and 3.92 in rabbits. On the basis of these results it can be concluded that binding of pethidine to erythrocytes does not play an insignificant part in total pharmacokinetics of pethidine.
2635070
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-0.009004352, 0.00072569057, -0.00986443, -0.03374151, -0.043824267, -0.046364803, -0.012517438, -0.031333294, 0.052610293, 0.020086123 ]
[The effect of hydrogenated ergot alkaloids on immune functions. II. The primary antibody response and proliferative activity in mouse spleen cells in vitro].
The present paper investigated the proliferative response of murine splenic cells in the tissue culture after stimulation with the polyclonal activators PHA; ConA and PWM. Proliferation of cells and DNA synthesis were measured by means of radioactively labelled thymidine. Furthermore; the primary antibody response of murine splenic cells in the tissue culture after activation with sheep red blood cells was examined. The response was measured by determining the number of plaque forming cells (PFC). The numbe
2635071
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0.053861085, 0.017882627, -0.02246655, 0.009127868, -0.0637485, 0.005879813, 0.062789075, 0.0036278279, 0.012186037, 0.0034379417, 0.054180894, 0.030968126, 0.011926193, -0.02311949, 0.00023090342, -0.014791144, 0.0109467795, 0.039896112, -0.03328674, -0.07728706, -0.0272237, -0.03896334, -0.30488414, -0.007848634, 0.046398886, -0.022759706, -0.079472415, 0.0116396975, 0.0073822467, -0.010680272, -0.061030127, 0.025518056, 0.0675329, 0.011479793, 0.068598926, 0.011539757, -0.009507641, -0.009221146, 0.013431958, -0.04765147, -0.0054900465, -0.07201022, 0.059057973, -0.050369844, 0.11886217, -0.0028682826, 0.020441094, 0.0027783366, 0.010253861, 0.03864353, -0.02567796, 0.0025218234, 0.024198845, 0.008255058, 0.030861523, -0.0011651358, -0.0054334137, 0.025837863, -0.023785759, -0.016789947, -0.07238333, 0.029449034, -0.053034913, 0.043227453, -0.05396769, -0.019401718, 0.07169041, -0.02346595, -0.03003535, -0.08656151, 0.0031114705, -0.03344664, -0.08229739, -0.018242411, 0.031767648, 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[The effect of hydrogenated ergot alkaloids on immune functions. II. The primary antibody response and proliferative activity in mouse spleen cells in vitro].
r of PFC's was determined by the plaque method of local haemolysis; in modification by the drop method. In these tests the ergot alkaloids dihydroergocornine; dihydroergocristine; dihydro-alpha-ergocryptine and dihydro-beta-ergocryptine were evaluated in two doses; 600 and 1200 micrograms/kg/day p. o. for the period of 14 days. Dihydroergocornine in these tests increased the primary antibody response in a statistically significant manner; on the other hand; after its administration in the higher dose decrea
2635071
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0.009010878, 0.004332153, 0.03476386, -0.026059566, -0.021740744, 0.018421648, -0.02865886, -0.031831328, 0.005915055, -0.0035390358, 0.039482575, 0.035990193 ]
[The effect of hydrogenated ergot alkaloids on immune functions. II. The primary antibody response and proliferative activity in mouse spleen cells in vitro].
sed proliferation after PHA was found. The finding after dihydroergocristine administration was of interest. This ergot alkaloid slightly increased proliferation of cells after PHA and PWM as well as the primary antibody response of murine cells. After the administration of dihydro-alpha-ergocryptine increased proliferation after stimulation with PWM and increased primary antibody response; and after the administration of dihydro-beta-ergocryptine increased proliferation of cells after stimulation with PHA
2635071
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[The effect of hydrogenated ergot alkaloids on immune functions. II. The primary antibody response and proliferative activity in mouse spleen cells in vitro].
were found.
2635071
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[5-Substituted 3-mercapto-4H-1,2,4-triazoles as a potential thyrostaticagent].
Within the framework of the study of the relationships between the structure and thyreostatic activity of cyclic analogues of thiourea; a series of 5-substituted 3-mercapto-4H-1;2;4-triazoles was prepared in order to answer the question of how the presence of another nitrogen atom in position 1 and the presence of the substituent in position 5 would influence thyreostatic activity. The synthesis was based on 1-acylsubstituted thiosemicarbazides which were cyclized to the pertinent 3-mercapto-4H-1;2;4-triazo
2635072
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-0.053483102, -0.010760228, -0.018061811, -0.008852011, 0.006930541, -0.005270789, 0.0075202333, 0.07638172, -0.04171576, -0.027059589, -0.0106012095, 0.026834313, 0.021957757, 0.05231697, 0.01893641, 0.027324619, 0.025230879, -0.01673666, 0.0144176455, 0.05186642, 0.0146959275, -0.2690587, -0.020579599, 0.004982569, 0.045267165, -0.043915514, -0.0007213792, 0.041662756, -0.029259339, -0.03662718, -0.003561344, -0.017677518, 0.082106374, 0.04651281, 0.06827179, 0.0037435524, -0.03758129, 0.034665957, -0.04179527, -0.0052111573, 0.007639497, -0.0149079515, -0.011773969, 0.1594422, -0.0021815302, 0.004240484, 0.07150516, -0.012111883, 0.011164399, -0.053112064, 0.03880043, -0.0038893188, -0.020606102, 0.08788403, 0.013218383, 0.00999164, 0.03564657, -0.04362398, 0.00994526, -0.0070431787, 0.021918, -0.052343473, 0.005843917, -0.06874885, -0.0026188302, 0.09853825, -0.056822486, -0.022978123, -0.003620976, -0.0107005965, 0.03400338, -0.03074351, -0.056451444, -0.02479358, -0.04054963, 0.014364639, 0.0045287046, -0.055338316, -0.008268944, 0.03522252, 0.006380603, -0.034904484, 0.019373711, 0.0002671008, 0.083166495, 0.021864995 ]
[5-Substituted 3-mercapto-4H-1,2,4-triazoles as a potential thyrostaticagent].
les. Furthermore; esters of dicarboxylic acids were used; which with thiosemicarbazide in alcoholate yielded the pertinent mercaptotriazoles. Selected 5-substituted 3-mercapto-4H-1;2;4-triazoles were tested on adult male rats of Wistar strain. The effects of the agents under study on the level of serum thyroxine (T4); total body weight; heart weight; thyroid gland weight; and the number of leucocytes were investigated. The results of the tests show that whereas the presence of nitrogen in position 1 influen
2635072
[ -0.03657952, 0.039783567, 0.016020227, 0.0027935272, 0.029023312, -0.009031404, 0.067071356, 0.08031474, -0.12314215, 0.009151556, 0.009018053, -0.034309987, 0.038395148, 0.019344425, 0.0077764858, -0.042373504, -0.039836966, -0.05740582, -0.0422667, -0.014618458, -0.008504071, 0.00805684, 0.03799464, 0.01616708, 0.050276816, 0.021613957, 0.0014760303, 0.038181543, -0.042774007, -0.15774584, 0.063707106, -0.014885462, -0.023416232, -0.023563085, -0.05842043, 0.0016762832, -0.028195601, -0.014044399, -0.03163995, -0.01754215, 0.08223717, 0.060236055, -0.004482326, 0.008857851, -0.02318928, -0.050276816, -0.03804804, 0.045924652, 0.086135425, 0.058206826, 0.0033826043, -0.0074293804, 0.069420986, 0.074921265, -0.0063480153, -0.0493156, -0.020198837, 0.0027718332, -0.022788774, 0.07454746, 0.028355803, 0.0010271303, -0.13926919, 0.017408649, 0.07668349, 0.031933654, -0.04077148, -0.013650569, -0.014271353, 0.04984961, -0.04637856, -0.0015502908, 0.035645008, 0.03655282, -0.030652035, -0.0069487737, 0.027608193, -0.102155656, -0.008303818, -0.07529507, -0.011561264, -0.016420733, 0.0069754743, -0.038448546, -0.05284005, -0.042774007, 0.00042032238, 0.0031139317, -0.046805765, 0.011274235, -0.027875196, -0.045070242, -0.022027813, -0.06034286, -0.018049456, -0.010993881, -0.0018339823, -0.010052693, -0.0070622503, 0.3936704, 0.039703466, -0.043788623, -0.056551404, -0.017288497, -0.021213451, -0.009919191, 0.01021957, -0.06055646, 0.005887434, 0.09564076, 0.08298478, -0.03361578, 0.044429433, -0.060182657, -0.04768688, 0.016447434, 0.07582908, -0.015285968, -0.014778661, 0.07689709, 0.005730569, -0.007963388, 0.020786246, -0.0136972945, 0.053160455, 0.043254614, -0.036072213, 0.0561242, 0.014111151, 0.05198564, 0.036285818, -0.00264, -0.0048861695, 0.018116208, 0.006524905, 0.008684299, 0.08175656, -0.014671858, 0.030758837, -0.009305082, -0.027714994, -0.07636309, -0.04013067, -0.09265032, -0.06183808, 0.0703822, 0.022641921, 0.0077030594, 0.009258357, 0.043815322, 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-0.038395148, 0.004499014, -0.06397411, -0.043494917, -0.015953477, -0.034897394, -0.049662706, 0.038822353, 0.050276816, -0.048968498, -0.05270655, -0.04061128, 0.07422706, -0.009411884, -0.040958382, 0.04069138, 0.007916663, 0.01128091, -0.055803794, -0.039062656, 0.033322074, 0.05852723, -0.016353983, 0.06536253, -0.0060776738, -0.009819064, -0.0421866, 0.07887292, 0.008370569, -0.04151909, -0.053614363, 0.04146569, -0.025592314, -0.03169335, -0.066697545, -0.028916512, -0.009151556, -0.093985334, -0.02894321, -0.00036587863, -0.081062354, -0.054522175, 0.019504627, 0.024978206, 0.017889254, 0.008797775, 0.005944172, 0.0062145134, 0.06173128, -0.002853603, -0.035378, 0.033455577, -0.034710493, -0.06050306, 0.00616445, -0.014885462, 0.010700177, -0.0003815234, 0.010733552, 0.039596662, 0.031906955, -0.019317726, -0.000739684, 0.005053047, 0.00015467446, 0.073426045, 0.03802134, 0.011928394, 0.09361153, -0.005884096, 0.0420798, 0.029183514, -0.025031606, -0.014645158, -0.016287232, -0.03230746, -0.014938862, -0.0420531, 0.0010813654, 0.06760536, -0.014671858, -0.02389684, 0.0043254616, -0.04968941, 0.00055486726, 0.017275145, 0.027140936, 0.033215273, 0.029610721, -0.04344152, -0.015579672, 0.031906955, 0.015606372, -0.26486775, -0.024911454, 0.0016754488, 0.048114084, -0.046218358, -0.048274286, 0.07801851, -0.011694767, -0.0053601013, -0.037353832, -0.011628015, 0.032761365, 0.071129814, 0.019878432, 0.010973856, -0.039730165, 0.026767131, -0.029023312, -0.031933654, 0.019504627, -0.044749837, -0.011634691, 0.16607636, 0.04768688, -0.046832465, 0.06808597, -0.013777396, 0.0019140835, -0.020559292, 0.05115793, 0.043227915, 0.007242478, 0.07273184, 0.0026266498, 0.03439009, 0.02531196, -0.04563095, -0.015232567, -0.030758837, 0.041385587, -0.033428874, -0.016540885, -0.07444066, -0.051077828, 0.06947439, -0.029877724, 0.000030637642, 0.007816536, -0.016594285, 0.002685057, -0.0070822756, -0.016834589, 0.002685057, -0.03172005, 0.06504212, 0.011000557, -0.019878432, -0.012175373, 0.027221037, -0.00596086, -0.051878836, 0.012248799, -0.061357472, 0.08282458, 0.070275396 ]
[ -0.03657952, 0.039783567, 0.016020227, 0.0027935272, 0.029023312, -0.009031404, 0.067071356, 0.08031474, -0.12314215, 0.009151556, 0.009018053, -0.034309987, 0.038395148, 0.019344425, 0.0077764858, -0.042373504, -0.039836966, -0.05740582, -0.0422667, -0.014618458, -0.008504071, 0.00805684, 0.03799464, 0.01616708, 0.050276816, 0.021613957, 0.0014760303, 0.038181543, -0.042774007, -0.15774584, 0.063707106, -0.014885462, -0.023416232, -0.023563085, -0.05842043, 0.0016762832, -0.028195601, -0.014044399, -0.03163995, -0.01754215, 0.08223717, 0.060236055, -0.004482326, 0.008857851, -0.02318928, -0.050276816, -0.03804804, 0.045924652, 0.086135425, 0.058206826, 0.0033826043, -0.0074293804, 0.069420986, 0.074921265, -0.0063480153, -0.0493156, -0.020198837, 0.0027718332, -0.022788774, 0.07454746, 0.028355803, 0.0010271303, -0.13926919, 0.017408649, 0.07668349, 0.031933654, -0.04077148, -0.013650569, -0.014271353, 0.04984961, -0.04637856, -0.0015502908, 0.035645008, 0.03655282, -0.030652035, 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-0.03636592, 0.047419876, 0.0056671556, 0.054388672, -0.042106498, 0.0210399, -0.02958402, -0.009191606, -0.06269249, 0.0246311, -0.04501684, -0.042560406, 0.042373504, 0.078552514, -0.00013047724, 0.0175822, 0.013143262, 0.006645057, -0.015112415, 0.02254847, -0.0210933, -0.007088951, -0.06803257, 0.02035904, -0.016674386, 0.0046124905, 0.012095272, 0.05115793, 0.06546933, 0.020545943, 0.047339775, 0.061784677, -0.05006321, -0.00043680152, -0.016580936, 0.043201216, -0.054895982, -0.013423616, 0.011247535, 0.057085413, 0.0038481923, 0.024030343, -0.061464272, 0.01893057, -0.04085158, 0.008323844, -0.055269785, 0.052306045, 0.032467663, 0.03286817, 0.06637714, 0.0048060683, 0.04968941, 0.038501948, 0.004485664, 0.0027201013, 0.020185487, -0.07497466, 0.067979164, -0.043815322, -0.005640455, 0.05687181, -0.04632516, 0.022388268, 0.0074894563, 0.03382938, 0.04848789, 0.009258357, 0.025779217, 0.07924673, 0.050864223, -0.06958119, -0.0175822, -0.3007531, -0.025178459, 0.0016696082, 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-0.019878432, -0.012175373, 0.027221037, -0.00596086, -0.051878836, 0.012248799, -0.061357472, 0.08282458, 0.070275396 ]
[5-Substituted 3-mercapto-4H-1,2,4-triazoles as a potential thyrostaticagent].
ced the thyreostatic activity of the agents prepared in an insubstantial manner only; the presence of a substituent in position 5 acts; except a methyl or ethyl group; dystherapeutically; and with the increasing volume of the substituent therapeutic activity disappears regardless of the fact whether an aliphatic or aromatic substituent is concerned.
2635072
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[Mechanisms of repair of the brain, spinal cord and peripheral nerves in relation to resolving problems of demyelination and toxic injury].
nan
2635073
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[Developmental aspects of regeneration of the spinal cord (observations on chick embryos)].
The reaction of the embryonic spinal cord to mechanical transversal myelotomy has some general features: 1. It is above all a glial reaction and repair by a glial scar which is the more subtle; the younger the damaged embryonic tissue. 2. The younger the spinal cord; the more powerfully it responds by proliferative reactions. 3. We never observed restoration of the original spinal architecture. The older the embryo; the more marked the defects of the grey and white matter. 4. During transversal myelotomy in
2635074
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[Developmental aspects of regeneration of the spinal cord (observations on chick embryos)].
older embryos after damage of already develop spinal pathways irreversible disconnection of the spinal cord from higher compartments of the CNS occurs and this is manifested by a marked reduction of the spontaneous activity of the spinal generator of embryonic motorics with all sequelae for its further morphological and functional development.
2635074
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-0.048006084, 0.008805536, 0.0032772108, -0.0008818797, -0.017982388, 0.024997642, 0.04028798, -0.006116797 ]
[The development of the brain and perinatal hypoxia].
The authors describe the development of dendrite structure of pyramidal cells of the CA 1 area of the hippocampus in the laboratory rat. The postnatal dendrite growth comprises their eventual branching and increasing number of dendritic segments. The final number of segments is reached first at the terminal branching of the apical dendrite and at the proximal lateral fibres (by the 10th day). In basal dendrites the branching is terminated on the 15th day of postnatal life. On the main stem and preterminal f
2635075
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[The development of the brain and perinatal hypoxia].
ibres of the apical dendrite the position comparable with the adult brain is reached at the age of 25 days. Repeated hypobaric hypoxia influenced the mentioned dendrite development in a quantitative way. In particular the number of dendritic branches and the density of dendritic spikes of pyramidal cells was lower. Hypoxia influenced in a similar way also interneurones of the hippocampus even when their number increased. The authors assume therefore that exposure to intermittent hypoxia during development l
2635075
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[The development of the brain and perinatal hypoxia].
eads to reduced input information. Conversely interneurones of the hippocampus are more resistant to oxygen deficiency; but the thus created disbalance obviously is the basis of the unbalanced character of stimulation and inhibition phenomena.
2635075
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[Does a "transcortical" loop of the long-latency muscle reflex exist?].
EMG responses were produced by electric stimulation of the dermal branches of the nn. digilates of the index finger of the right hand and recorded from the m. interosseus dorsalis I. during its slight isometric contraction. The mean initial latency of a long-latency muscular reflex was 50.68 ms in men and 49.13 in women. The author mentions some arguments indicating the probable existence of a transcortical loop: The latency of long-latency reflexes increases gradually from proximal to distal muscles. The s
2635076
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[Does a "transcortical" loop of the long-latency muscle reflex exist?].
hort-latency component of the somatosensory evoked potential N20 appears mid-time between the time of the stimulus and the onset of the long-latency reflex and thus the time interval in the long-latency reflex is sufficient for a transcortical loop. The author found a facilitation of the muscular reflex response as well as of the preparatory cortical potential during the preparatory period of voluntary flexion of the fingers during concurrent electric stimulation of the peripheral nerve. The late reflex com
2635076
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0.012693342, -0.023866128, 0.014623788, -0.008171339, -0.01593279, -0.009559673, -0.011873564, -0.04260203, 0.05124937, -0.016514568, 0.051646035 ]
[Does a "transcortical" loop of the long-latency muscle reflex exist?].
ponent increases considerably and is better synchronized during the movement of the thumb instead of isometric contraction; because during kinetic innervation afferent impulses reach the precentral cortex at a higher facilitated level. These results document well the modifiable; plastic behaviour of transcortical reflexes. The method of long-latency reflexes can be used in electrophysiological diagnosis of disorders of the CNS and it is promising also in therapeutic stimulation rehabilitation and in locomot
2635076
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[Does a "transcortical" loop of the long-latency muscle reflex exist?].
or reeducation.
2635076
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[The new hemorheologic drug VULM 957 improves cerebral circulation].
The authors investigated the effect of a newly synthetized haemorheological drug VULM 957 for basic haemorheological parameters in vitro and on the cerebral flow in vivo. It was revealed that substance VULM 957 inhibits in a dose-dependent and time-dependent way the platelet aggregation; reduces the viscosity of blood; increases the deformability of red blood cells and increases the cerebral blood flow. Analysis of possible mechanisms of action of VULM 957 indicates that the observed positive haemorheologic
2635077
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[The new hemorheologic drug VULM 957 improves cerebral circulation].
al effects are due to the influence on the fluidity of the platelet and red cell membrane. The increased cerebral blood flow after administration of VULM 957 depends obviously on the reduced viscosity of the blood and the inhibited formation of platelet microaggregates. The presented results justify the assumption that VULM is a perspective substance in the therapy of cerebrovascular diseases.
2635077
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[Periodic discharges in clinical electroencephalography].
The authors recorded generalized and focal periodic discharges in 49 EEG tracings from 27 patients aged 5 to 75 years. According to the shape of the waves and their complexes generalized periodic discharges were formed by slow waves; sharp waves or spikes; triphasic waves and periodic activity of the "suppression burst" type. Focal periodic discharges had the shaps of slow waves and so-called periodic lateralized epileptiform discharges. Six patients suffered from Creutzfeldt-Jacob's disease and from herpet
2635079
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0.047184214, 0.073314965, 0.021890817, -0.03851827, 0.04931083, 0.024868075, -0.0017694081, -0.043994296, -0.045881666, 0.021824362, 0.014793249 ]
[Periodic discharges in clinical electroencephalography].
ic encephalitis. Four had an acute cerebrovascular attack. Three suffered from subacute sclerotizing panencephalitis. Other conditions found included metabolic brain damage; post-traumatic purulent meningitis; anoxic encephalopathy and partial motor convulsions. Different types of periodic discharges were found in the same disease and even in the same patient and conversely one type of periodic discharges is found in different diseases. The authors assume that periodic discharges are not specific; have a di
2635079
[ -0.008759913, -0.013783687, -0.00053832104, -0.013163221, 0.0036193852, 0.017599886, 0.07733809, 0.045500845, 0.0056609185, -0.012996429, -0.015638413, -0.039336212, 0.005864405, -0.0012867999, -0.04667506, -0.020562112, -0.06548919, -0.021936476, 0.009360365, 0.034025557, -0.009133527, 0.0077991914, 0.03506634, -0.0021599557, -0.0025735998, -0.005697613, 0.025912797, -0.036027063, -0.05828378, -0.16609809, -0.04950385, 0.048729938, -0.04429994, -0.0652757, 0.0321308, -0.025539184, -0.04205826, 0.1058395, 0.033064835, 0.021923134, 0.019227777, 0.03650742, 0.057162937, -0.0036494078, 0.0051838937, -0.049236983, -0.052332643, 0.018707385, 0.1628957, 0.0085731065, -0.0061212643, -0.042858858, 0.069385454, 0.050331138, -0.045954518, -0.038562298, 0.0029071837, 0.008046044, 0.024111444, 0.015144709, 0.0107680885, 0.013643581, -0.09425747, 0.050598007, 0.033064835, -0.020321932, -0.051265173, -0.03295809, 0.019107686, 0.011742153, -0.040803984, -0.001014929, 0.023110693, 0.034212366, 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[ -0.008759913, -0.013783687, -0.00053832104, -0.013163221, 0.0036193852, 0.017599886, 0.07733809, 0.045500845, 0.0056609185, -0.012996429, -0.015638413, -0.039336212, 0.005864405, -0.0012867999, -0.04667506, -0.020562112, -0.06548919, -0.021936476, 0.009360365, 0.034025557, -0.009133527, 0.0077991914, 0.03506634, -0.0021599557, -0.0025735998, -0.005697613, 0.025912797, -0.036027063, -0.05828378, -0.16609809, -0.04950385, 0.048729938, -0.04429994, -0.0652757, 0.0321308, -0.025539184, -0.04205826, 0.1058395, 0.033064835, 0.021923134, 0.019227777, 0.03650742, 0.057162937, -0.0036494078, 0.0051838937, -0.049236983, -0.052332643, 0.018707385, 0.1628957, 0.0085731065, -0.0061212643, -0.042858858, 0.069385454, 0.050331138, -0.045954518, -0.038562298, 0.0029071837, 0.008046044, 0.024111444, 0.015144709, 0.0107680885, 0.013643581, -0.09425747, 0.050598007, 0.033064835, -0.020321932, -0.051265173, -0.03295809, 0.019107686, 0.011742153, -0.040803984, -0.001014929, 0.023110693, 0.034212366, 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0.033305015, 0.029515503, -0.052866377, 0.02540575, 0.026246382, 0.02174967, 0.010948224, -0.07904604, 0.05267957, -0.012309246 ]
[Periodic discharges in clinical electroencephalography].
fferent aetiology but obviously a common pathophysiological mechanism. From the EEG alone conclusions on the aetiology can be drawn only with a limited probability. It is necessary to use a comprehensive approach in their evaluation; taking account age; the clinical picture and development as well as results of other examinations. The 70.3% mortality in the group provides evidence that periodic discharges are a serious finding as regards the prognosis of the disease.
2635079
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[Erythrocyte deformability in patients with acute ischemic cerebrovascular stroke].
The authors investigated in a group of 40 patients the deformability of the red cells; using the disintegration method by means of brilliant cresyl blue. The control group was formed by blood donors from the blood transfusion station. The disintegration of the red cells was investigated in vitro in isotonic NaCl solution and in Krebs-Ringer solution with two concentrations of brilliant cresyl blue; i.e. 0.25 and 0.5 nmol/l1. It was revealed that the disintegration of red cells was significantly lower in Kre
2635078
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[Erythrocyte deformability in patients with acute ischemic cerebrovascular stroke].
bs-Ringer solution in blood donors and patients in both concentrations of brilliant cresyl blue that in isotonic NaCl. In patients where blood samples were collected within 24 hours after the attack; no significant difference was found in the disintegration of red cells as compared with blood donors. There was no significant difference in the disintegration of red cells in patients 24 hours after the attack and 10 to 20 days after the attack. The authors conclude that in the above conditions no substantial
2635078
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[Erythrocyte deformability in patients with acute ischemic cerebrovascular stroke].
changes in the deformability of the red cells occur.
2635078
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-0.00685653, -0.010139753, 0.056856457, -0.055748865, 0.039767876, -0.05754211, -0.04401365, 0.020886045, 0.02211231 ]
[Duffy blood groups and HLA antigens in hereditary motor-sensory neuropathy].
The Duffa system (Fya Fyb) and HLA antigens were examined in 86 subjects (39 affected; 47 healthy) in 17 families with HMSN type I; II and III. They recorded the incidence of autosomal dominant as well as recessive (possibly sporadic) forms. In the autosomal dominant form of HMSN type I a close relationship was detected between genes coding the investigated disease and blood cell signs Fya and Fyb. Recombination was found only in 9.1% of the cases. Investigation HLA antigens revealed marked reduction of the
2635080
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0.022777831, -0.042531, 0.0037775117, 0.014420211, -0.009777089, -0.050357975, -0.009246446, 0.0034060618, -0.058052294, 0.08490281, 0.0072034723 ]
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[Duffy blood groups and HLA antigens in hereditary motor-sensory neuropathy].
B27 antigen in the investigated patients. A striking sign in families with the autosomal dominant form of HMSN type I was an identical haplotype of the majority of parents.
2635080
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[The sleep apnea syndrome].
Polygraphic nocturnal records make it possible to differentiate different forms of the sleep apnoea syndrome; depending on the predominating type of apnoea--central or obstructive. In mixed apnoea always one component predominates. On five typical cases of sleep apnoea the authors describe basic symptoms; principles of diagnosis and pathophysiological mechanisms of their development. In the clinical picture usually several factors and pathophysiological systems participate; most frequently functional disord
2635081
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[The sleep apnea syndrome].
ers of respiratory centres and tonigenetic structure along with their afferentation or inhibition by afferent stimulation. The authors describe therapeutic approaches. Tracheostomy is recommended nowadays only in vital indication.
2635081
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[Basilar artery migraine].
The author describes two clinical observations of migraine of the basilar artery: with infarction of the cerebellar hemisphere in a 21-year-old woman and migraine equivalents of transient homonymous hemianopsia in a 27-year-old man. The author analyzed the clinical picture and assessed seven diagnostic criteria of migraine of the basilar artery. In the prophylaxis of migrainous attacks in both instanes metipranolol-80 mg/day-proved effective.
2635082
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0.046600845, 0.02415745, -0.010431626, 0.051876917, -0.016015692, -0.04301204, -0.0014487439, 0.057581503, -0.027585557, -0.030397678, -0.030210203, -0.025148386, 0.00007726006, -0.055921014, 0.028362237, 0.000170422, -0.044833224, -0.038218047, 0.014689978, 0.012507238, -0.26867798, -0.026179496, 0.02889788, -0.011984987, 0.01431503, 0.003947011, -0.0043119173, 0.0034816721, -0.07531125, -0.018466255, -0.004887732, 0.04349412, 0.024786828, 0.049573656, 0.0054133306, -0.013277223, 0.031013666, 0.042047888, 0.018961722, -0.04014636, 0.02098377, 0.036878943, 0.10809253, 0.022162182, -0.04108373, -0.019738404, 0.058652785, -0.011422563, -0.0074387267, 0.011884554, -0.02466631, -0.04780604, 0.075418375, 0.008235494, 0.033316925, 0.093040995, -0.07675748, -0.02838902, 0.042128235, 0.009654945, 0.004552956, 0.035111327, -0.0547426, 0.011536387, -0.014167728, -0.03326336, -0.012641149, 0.04041418, -0.023072774, 0.040119577, -0.024853783, -0.049948607, 0.028281892, 0.021907752, 0.030665498, -0.039450023, 0.03377222, -0.068883546, -0.024331532, -0.048636284, -0.026380362, -0.03221886, -0.034093607, 0.11612716, -0.0111681335 ]
[Dilatation of malignant esophageal stenoses using a balloon catheter].
The paper summarizes the experience with the dilatation of malignant oesophageal stenosis by a balloon catheter. In a patient after gastrectomy with a relapse of the tumorous process the author performed 10 dilatation interventions by a balloon 22 mm wide. After a short interval of renewed normal passage; marked swallowing difficulties always rapidly returned. The patient died 24 hours after a subsequent surgical revision and an attempt to remove the tumour.
2635084
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0.07185388, 0.003031585, -0.011115812, 0.06329098, -0.01982497, -0.01580945, 0.023933565, -0.028959613, 0.081427306, 0.029996734 ]
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0.07185388, 0.003031585, -0.011115812, 0.06329098, -0.01982497, -0.01580945, 0.023933565, -0.028959613, 0.081427306, 0.029996734 ]
[Naltrexone in narcolepsy. Initial experience].
The administration of 550 mg naltrexon in the course of 13 days did not four patients with narcolepsy-cataplexy to improvement of symptoms of the disease and did not improve their appetite or increase their body weight. No side-effects of naltrexon were observed.
2635083
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[The Mevatrom KD 80/67 linear accelerator].
Technical equipment of radiotherapeutic wards is presently supplemented with irradiators on the principle of a linear accelerator. The paper briefly describes the principle of linear accelerator with standing wave and its basic technical parameters. Data on electric; mechanic and densitometric properties of this apparatus and accessories are presented. Therapeutic beams of bremsstrahlung and electron radiation were characterized in the whole range of energy; i.e. 0.961 and 3.204 pJ (6 and 20 MV) for bremsst
2635085
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[The Mevatrom KD 80/67 linear accelerator].
rahlung and 0.961 to 3.364 pJ (6 to 21 MeV) for electron radiation. In the last part the performed hygienic measurements are also described.
2635085
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[Computer tomography in the differential diagnosis of edema of the extremities].
Computer tomography provides valuable information for differentiating some cases of extremity edemas of acute and chronic venostatic origin and lymphedema--primary and secondary; in malignant processes. The paper presents graphic representation of individual kinds of changes and observed densities in 33 patients.
2635087
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0.033865925, 0.042609777, -0.048342153, 0.031620525, -0.021106765, 0.05922574, -0.06979233, 0.05233104, -0.062501386, -0.06408638, 0.04992714, 0.04813082 ]
[Radiographic signs of rotator cuff tears in the shoulder].
In 42 patients affected by disruption of the whole layer of the shoulder rotator collar the authors compared radiographic changes on a simple radiograph in anterior-posterior projection with operation findings. The proliferative changes on the large trochanter of humerus and the humeroacromial distance were decisive for prognosis of the operation therapy for the disrupted collar. The patients with a shorter humeroacromial distance were affected; after the operation; by a worse external rotation of the arm;
2635086
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0.0065662, -0.014951347, -0.0091147255, 0.045413718, -0.029396322, -0.021933973, 0.014245089, 0.017150074 ]
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0.0065662, -0.014951347, -0.0091147255, 0.045413718, -0.029396322, -0.021933973, 0.014245089, 0.017150074 ]
[Radiographic signs of rotator cuff tears in the shoulder].
worse extension and muscular strength of the arm in the extension position. Radiographic changes observed on the shoulder together with other factors are decisive for the strategy of conservative and operation therapy.
2635086
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Quantitative and morphological studies of the bones by mathematical morphology--theory and practice of mathematical morphology.
To quantitatively analyze internal bone structures; trabecular bones were quantitatively studied through the application of mathematical morphology. Mathematical morphology considers the shape of the analyze objects and utilizes image processing theory in an approach that is extremely effective on for studying the complex shapes of trabecular bones. This paper describes quantitative studies made of trabecular bone density and width; trabecular specific length per unit area; and trabecular bone orientation.
2635089
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Metal surface modification with ceramic film coating.
nan
2635088
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Quantitative and morphological studies on the trabecular bones in the condyloid processes of the Japanese mandibles. Comparisons between dentulous and edentulous specimens.
Using dentulous and edentulous specimens; mathematical morphology was applied to quantities bone morphology measurements; of the trabecular bones in the condyloid processes; which form the temporomandibular joint and are the center of mandibular motion. There is a tendency for trabecular bone density and width in edentulous specimens to be comparatively lower than for dentulous specimens and a similar decrease in continuity of the trabecular bones. Values for specific length are highest in dentulous specime
2635090
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0.027907621, 0.017565541, -0.023429608, -0.015633065, 0.03169261, 0.035530906, -0.06631725, -0.0080897445, -0.05629503, -0.09729018, 0.05938699, 0.016805878 ]
Quantitative and morphological studies on the trabecular bones in the condyloid processes of the Japanese mandibles. Comparisons between dentulous and edentulous specimens.
ns; indicating a greater degree of interlocking. A degree of regularity is observed in trabecular bone orientation; in edentulous specimens trabecular bones other than major ones are fewer and thinner.
2635090
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[ 0.049300216, -0.004771415, 0.011538629, -0.020764247, 0.029051442, 0.022945087, 0.07940903, 0.019429307, 0.014182073, -0.06005903, -0.0032861305, -0.07031559, 0.00997239, 0.03528997, -0.053688332, 0.0059609646, -0.004074207, 0.00892823, -0.010798465, 0.034549803, 0.091410264, -0.032540787, 0.011353589, -0.047423374, 0.03513136, 0.08955986, -0.04020677, -0.030848984, 0.03912296, -0.18705004, 0.040471118, 0.045599397, 0.04623382, -0.015080844, 0.053344686, 0.05598813, -0.095322564, 0.016587606, -0.058208622, 0.029289352, 0.010084736, 0.016785864, -0.01149237, -0.011598107, -0.038435664, 0.045943044, -0.0054521016, 0.02463689, -0.0030052646, 0.01941609, 0.003172132, -0.0256414, -0.020526337, 0.03835636, 0.0014175464, 0.014895802, 0.04020677, -0.028073367, 0.024174288, 0.0312455, 0.04382829, -0.0025013583, -0.12561642, 0.039757386, 0.114302486, 0.05183792, 0.040180337, -0.03470841, -0.025760354, 0.005703229, 0.06058772, 0.015503795, 0.0073355553, 0.054296326, 0.04068259, -0.048586488, 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-0.00067655626, 0.013547647, 0.025086276, -0.02778259, -0.07496805, 0.08131231, -0.054719277, 0.02568105, 0.00047334156, -0.0016802386, 0.015834225, 0.017737504, 0.042955954, 0.033598162, 0.032884434, -0.026553387, 0.008558148, -0.04747624, 0.0046062, 0.041369885, -0.019217832, -0.30367875, 0.013382431, 0.00058073143, -0.008749797, -0.0092190085, 0.0010036824, 0.038541403, 0.021715887, -0.004497158, 0.027359638, -0.058525834, -0.00018018782, 0.0119351465, -0.027280334, -0.021002157, -0.022495702, 0.121704124, -0.10071519, 0.06666764, -0.06254387, -0.008333455, -0.05646395, 0.16516234, 0.0026483997, 0.0028070062, 0.04670964, -0.0067870407, 0.00038825572, -0.028231975, 0.0064400886, 0.06264961, 0.0026368347, 0.014644676, 0.07084428, 0.040603288, 0.12646233, -0.014657893, 0.0055578393, 0.037669066, -0.0127149625, -0.015596315, -0.03870001, -0.071055755, 0.05730985, 0.07026272, -0.005065498, -0.007910504, 0.031219065, 0.02316978, 0.0062021785, -0.006681303, -0.00053612335, 0.028179105, 0.0069059953, 0.017169164, -0.057468455, -0.022812916, 0.012239142, -0.023870293, -0.02626261, -0.02293187, -0.059213128, -0.033571728, -0.03135124, -0.017512811 ]
High-resolution scanning electron microscopy of formative osteoblasts, with special emphasis on intracellular membranous organelles.
Formative osteoblasts in immature bone obtained from newborn rats were examined with a high-resolution scanning electron microscope. The three dimensional ultrastructures of intracellular membranous organelles in formative osteoblasts were revealed by the maceration and extraction of cytoplasmic soluble elements with dilute osmium tetroxide after DMSO (dimethyl sulfoxide) freeze-cracking in liquid nitrogen. Typical formative osteocytes covering self-produced unmineralized matrix were plumply ovoid or ellips
2635091
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High-resolution scanning electron microscopy of formative osteoblasts, with special emphasis on intracellular membranous organelles.
oid in shape. Their cytoplasms were filled with intracellular organelles related to matrix-formation such as Golgi apparatus; mitochondria; and well-developed rough endoplasmic reticulum (RER). The Golgi apparatus of formative osteoblast was composed of the three kinds of prominent elements; which were lamellar portions stacked several cisterns with some fenestrations; abundant vesicles; and vacuoles. The Golgi cisterns frequently extended continuing in a circle. A large number of spherical protrusions indi
2635091
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High-resolution scanning electron microscopy of formative osteoblasts, with special emphasis on intracellular membranous organelles.
cative of arising the vesicles and elongated tubular structures were usually observed in a part of the Golgi cisterns. The tubular structures which mediated between adjoining Golgi cisterns; or between the Golgi cisterns and RER in the Golgi area; presumably play an intercommunication role in secretion products. The RER was highly oriented in almost parallel rows from both the Golgi area and nucleus to the cell margins; while small in the Golgi area. The RER had enlarged fenestrations than that of the Golgi
2635091
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High-resolution scanning electron microscopy of formative osteoblasts, with special emphasis on intracellular membranous organelles.
cisterns. Minute ribosomes of about 28 nm were associated closely with the membrane surface of the RER facing the cytoplasmic matrix.
2635091
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-0.022240222, -0.034122705, -0.029969094, -0.06030623, 0.020005684, 0.020031974, -0.024317028, -0.048528902, 0.001453271, 0.026433267 ]
Ultrastructure of the organized sensory nerve endings in the lower lip mucosa of Mongolian gerbils (Meriones unguiculatus).
nan
2635092
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The effect of vitamin E on glycosylated hemoglobin levels in diabetic rats: a preliminary report.
The effect of vitamin E (D-alpha-tocopherol acetate) on glycosylated hemoglobin levels was investigated in streptozotocin-diabetic rats. The animals were divided into four groups: (a) Group 1: control group; (b) Group 2: diabetic group; (c) Group 3: diabetic group treated with low-dose vitamin E and (d) Group 4: diabetic group treated with high-dose vitamin E. Starting 24 hr after streptozotocin injections (60 mg/kg); Groups 3 and 4 received intraperitoneal injections of vitamin E on days 1; 4; 7; 11; 14; 1
2635093
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The effect of vitamin E on glycosylated hemoglobin levels in diabetic rats: a preliminary report.
8 and 21 at doses of 500 mg/kg and 1;000 mg/kg respectively. Vitamin E treatment did not prevent weight loss or improve glycemic control in diabetic animals but significantly suppressed the increase in glycosylated hemoglobin in Group 4 (7.7 +/- 0.6 mumols fructose/g hemoglobin versus 5.5 +/- 0.2 mumols fructose/g hemoglobin in Group 2 and Group 4 respectively). These levels were still significantly higher than the levels in healthy control group animals (2.6 +/- 0.1 mumols fructose/g hemoglobin). Further s
2635093
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The effect of vitamin E on glycosylated hemoglobin levels in diabetic rats: a preliminary report.
tudies on the suppressive effect of vitamin E are warranted.
2635093
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Comparison of the safety and effectiveness of human and bovine long-acting insulins.
Since ultralente insulin pharmacokinetics suggest faster absorption by human insulin when compared with bovine insulin using the subcutaneous route; the safety and efficacy of human ultralente in the outpatient setting was evaluated. Twenty type I patients participated in a randomized study using a crossover design of four six-week phases: (a) one daily injection of human ultralente; (b) two daily injections of human ultralente; (c) one daily injection of bovine ultralente and (d) two daily injections of bo
2635094
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0.027327642, -0.04327319, -0.04884484, 0.02072125, -0.018824235, 0.049083628, -0.05603493, 0.044493645, 0.01000908 ]
Comparison of the safety and effectiveness of human and bovine long-acting insulins.
vine ultralente. Pre-meal human regular insulin was used with ultralente insulins and comprised 39 +/- 2% of the total daily insulin dose. Total and ultralente daily insulin doses were lower with human ultralente insulin (51.3 +/- 3.0 total and 30.9 +/- 3.4 ultra lente u/day) when compared to bovine ultralente insulin (57.8 +/- 4.4 and 36.1 +/- 4.4 u/day; p less than 0.01); yet the metabolic control achieved was virtually identical during both phases: (hemoglobin Alc 8.6 +/- 0.2% human vs. 8.4 +/- 0.4 bovin
2635094
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