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Lesions of the caudal pontine reticular nucleus reduce spontaneous behavioural activity of rats differently in dorsal and ventral parts of the nucleus. | owed strongly reduced drinking from water bottles; did not eat pellets in their home cages and lost 5% of their body weight per day. This could be prevented by a supply with a cornflake pap. The ventral RPC lesion revealed no influence on food and water intake. Ambulatory activity in the OF was strongly reduced by dorsal lesions but not by ventralones. The habituation quotient increased only after ventral RPC lesions. Both lesion types increased the duration of immobilization. Exploratory activity was also | 2634960 | [
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Lesions of the caudal pontine reticular nucleus reduce spontaneous behavioural activity of rats differently in dorsal and ventral parts of the nucleus. | reduced after both lesion types; but significantly stronger after dorsal lesions. In a centrophobia test the dRPC rats were 6 times slower than before lesion; whereas vRPC rats remained unchanged compared with their preoperative values. The negativism-test revealed strong enhancement after dRPC lesions; but not so strong after vRPC lesions. The results indicate specialized subdivisions of the pontine reticular formation controlling differently spontaneous behaviour. | 2634960 | [
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Learning and retention of active avoidance are differently impaired after dorsal and ventral lesions of the nucleus reticularis pontis caudalis of rats. | Four groups of 8 adult male hooded rats of the Long-Evans strain were investigated before and after bilateral symmetric lesions of the nucleus reticularis pontis caudalis (RPC) in a Y-maze and in a jump test box. After dorsal (d) RPC lesions the retention of preoperatively learnt simple tasks in the Y-maze or in the jump test was not impaired whereas brightness discrimination in the Y-maze was neither retained nor relearned. Postoperative acquisition without preoperative experience was impossible for dRPC r | 2634961 | [
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Learning and retention of active avoidance are differently impaired after dorsal and ventral lesions of the nucleus reticularis pontis caudalis of rats. | ats in any of the tests. After ventral (v) RPC lesions there was no retention of active avoidance response in the Y-maze but rather normal retention of the jump test performance. The retention of brightness discrimination; however; was not impaired in the Y-maze after vRPC lesions. The relearning of the impaired active avoidance in the Y-maze was impossible for vRPC rats; though these rats showed intrasessional improvement; there was no retention between sessions. After retention of the simple jump test tas | 2634961 | [
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Learning and retention of active avoidance are differently impaired after dorsal and ventral lesions of the nucleus reticularis pontis caudalis of rats. | k the vRPC rats were not able to learn a go/no-go task in the jump test box. Acute extinction to the non-reinforced 2.5 KHz tone was prolonged. Intertrial responses in the jump test were reduced to zero after dRPC lesions; but significantly enhanced after vRPC lesions. The results indicate that CAR response initiation was reduced after dRPC lesions; but in vRPC rats the suppression of incorrect responses was reduced in the jump test. The lesions differently impair the control of learnt motor programs. | 2634961 | [
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The antihypoxic effect of ethymisole: a comparison with other nootropic drugs. | Ethymisole reveals a potent antihypoxic effect which is produced probably both by an acute free radical scavenging property and a persisting restitutive component of action. This is seen in its effect on posthypoxic inhibition of dopamine release from striatum slices of adult rats. Though ethymisole is considered a drug which increases brain adaptive potency; it does not modify the stimulus-response relation of potassium-evoked dopamine release in an adaptation-like manner; as it is seen after a long-lastin | 2634962 | [
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The antihypoxic effect of ethymisole: a comparison with other nootropic drugs. | g piracetam treatment. | 2634962 | [
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Inhibition of human lecithin: cholesterol acyltransferase activity by catecholamines in vitro. | The effects of L-adrenaline and L-noradrenaline on human lecithin: cholesterol acyltransferase (LCAT) activity were investigated in vitro. Both catecholamines are shown to be inhibitors of this enzyme. Despite inter-individual variations in the dose-response relationships calculated for both hormones; significant effects can be expected in the upper physiological range of concentration. Since diminished LCAT activity is known to be followed by a low level of HDL cholesterol and an increased concentration of | 2634963 | [
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Inhibition of human lecithin: cholesterol acyltransferase activity by catecholamines in vitro. | triglycerides; it is supposed that catecholamine mediated inhibition of LCAT activity may contribute to the development of stress mediated fluctuations in plasma lipoprotein concentrations. | 2634963 | [
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[Poly(galactosylglycerophosphate) with mannosyl side residues from the cell wall of Actinoplanes phillipinensis VKM Ac-647]. | The Actinoplanes philippinensis cell wall has several anionic carbohydrate-containing polymers. The major polymer is of poly(glycosylglycerol phosphate) type; its monomeric unit being O-alpha-D-mannopyranosyl-(1----4)-beta-D- galactopyranosyl-(1----1)-glycerol monophosphate. The phosphodiester linkages connect the C3 of glycerol units and the C6 of galactosyl ones; and the mannosyl residues form side branches of the teichoic acid's main chain. Chains without mannosyl residues were found in addition to the m | 2634964 | [
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[Poly(galactosylglycerophosphate) with mannosyl side residues from the cell wall of Actinoplanes phillipinensis VKM Ac-647]. | ajor teichoic acid. The structure of the polymers was established by chemical analysis; and 13C and 1H NMR spectroscopy. It is for the first time that a teichoic acid with mannosyl residues was found in bacterial cell walls. The phosphorylated mannan contains; in addition to mannose; 2-O-methylmannose. The main chain has alpha-1;2; alpha-1;3 and alpha-1;6 types of substitution; which was established by 13C NMR spectroscopy. | 2634964 | [
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[The structure of oligosaccharide fragments of glycoproteins from influenza virus A/Krasnodar/101/59/(H2N2)--heavy and light chains of hemagglutinin and neuraminidase]. | The structure and heterogeneity of carbohydrate chains of hemagglutinin (HA) and neuraminidase (NA); the surface glycoproteins of influenza virus A/Krasnodar/101/59 (H2N2); were investigated. Hemagglutinin was reduced with beta-mercaptoethanol and its heavy (HA1) and light (HA2) chains were separated by gel chromatography. Amino acid and sugar composition of HA1; HA2 and NA was elucidated. The carbohydrate chains of the glycoproteins were cleaved off by the alkaline LiBH4 treatment and oligosaccharides were | 2634965 | [
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[The structure of oligosaccharide fragments of glycoproteins from influenza virus A/Krasnodar/101/59/(H2N2)--heavy and light chains of hemagglutinin and neuraminidase]. | reduced with NaB[3H]4. They were fractionated by subsequent two-step HPLC on Ultrasphere-C8 and Zorbax-NH2 columns with simultaneous identification using nonlabelled oligosaccharides of known structures. Some of the major oligosaccharides isolated from HA1; HA2 and NA were thus identified as high mannose chains; containing 5-9 mannose residues; and complex chains; first of all biantennary chains having or not having bisecting N-acetylglucosamine and/or fucose residues. The approach which has been developed | 2634965 | [
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[The structure of oligosaccharide fragments of glycoproteins from influenza virus A/Krasnodar/101/59/(H2N2)--heavy and light chains of hemagglutinin and neuraminidase]. | enables one to study the structure and heterogeneity of carbohydrate chains starting from one nmole of a desialylated N-glycoprotein. | 2634965 | [
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[Isolation of the porcine alpha-interferon gene using simultaneous directed multipoint mutagenesis]. | A method of obtaining the pig alpha-interferon gene by means of simultaneous multidirected mutagenesis of the human alpha 2-interferon gene is presented. Nucleotide homology between these genes is 80.4%. Fourteen synthetic oligonucleotides forming a pig alpha-interferon gene's strand were ligated on a single-stranded template; carrying cDNA of the human alpha 2-interferon gene. The obtained DNA fragment was cloned in the single-stranded or double-stranded form. It was found that the method does not affect t | 2634966 | [
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[Isolation of the porcine alpha-interferon gene using simultaneous directed multipoint mutagenesis]. | he cloning efficiency. The primary structure of the gene was confirmed by sequencing. | 2634966 | [
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[Identification of a nature of mutation in the 12th exon of phenylalanine hydroxylase gene in patients with phenylketonuria]. | Upon amplification in vitro of the 12th exon area of the human phenylalanine hydroxylase gene followed by allele-specific hybridisation of the amplification product with synthetic probes and its sequencing by the Maxam-Gilbert method; a C----T transition causing phenylketonuria has been identified in Latvian patients. | 2634967 | [
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Management of cervical spine injuries. | nan | 2634968 | [
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Prophylactic transfusions in pregnant patients with sickle cell disease. | nan | 2634974 | [
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Controlled release of dopamine from a polymeric brain implant: in vivo characterization. | Intracerebral microdialysis was used to evaluate the long-term in vivo release of dopamine from ethylene-vinyl acetate (EVAc)-dopamine copolymer matrix discs for up to 65 days following striatal implantation. Dopamine release occurred through a single cavity present on one side of the disc; which was otherwise fully coated with an additional; impermeable layer of EVAc. At 20 days following implantation of the device; extracellular concentrations of dopamine within the striatum reached micromolar levels; ove | 2634975 | [
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Controlled release of dopamine from a polymeric brain implant: in vivo characterization. | r 200-fold greater than control values. Release of dopamine was shown to be stable and maintained for the 2-month duration of the experiment. Histological examination confirmed the biocompatible nature of the implant. There are potential applications of this technology to the treatment of Parkinson's disease and other neurological and psychiatric disorders. | 2634975 | [
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Re: Non-operative diagnosis of renal sinus lipomatosis simulating tumour of the renal pelvis. | nan | 2634976 | [
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N-acetylcysteine in the treatment of acetaminophen overdose. | nan | 2634982 | [
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Intraoperative assessment of lymph node involvement in gastric carcinoma. | This study compares the assessment of lymph nodes by the surgeon; at the time of operation; with the pathologist's assessment on the resected specimen in 85 cases of total gastrectomy with extended lymphadenectomy for gastric carcinoma. There was correlation in 67% of cases; in 28% the disease was overstaged; and in only 5% was it understaged by intraoperative assessment. This has important implications for the comparison of trials and management decisions based on surgical assessment. | 2634990 | [
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The natural history of carpal tunnel syndrome in lactation. | In a retrospective postal study of 27 women who have developed carpal tunnel syndrome (CTS) in the puerperium; the condition was found to affect predominantly elderly primiparous women (mean age 31.5 years). The condition was associated with breastfeeding in 24 women. The three who did not breastfeed had less severe symptoms which resolved within one month of onset. The symptoms developed a mean of 3.5 weeks following delivery; lasted 6.5 months and started to resolve within 14 days of weaning. Symptomatic | 2634992 | [
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The natural history of carpal tunnel syndrome in lactation. | treatments with either splintage; diuretics; non-steroidal anti-inflammatory drugs or steroid injections provided some benefit. Two patients required surgical decompression. All patients were symptom-free by one year. | 2634992 | [
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Depression-dependent exacerbation of tardive dyskinesia. | A middle-aged woman with a recurrent depressive illness showed worsening of her tardive dyskinesia during the depressive phases; with improvement on remission. | 2634996 | [
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The health care electoral paradox. | nan | 2634997 | [
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[Stomatitis from dentures: etiopathological and therapeutic considerations]. | Infection of the oral mucous membrane is frequent in patients with removable prostheses; either totally of partially; and particularly when the prostheses is palatal. The principal etiological factor causing the infection is accepted to be "Candidas" aided by the presence of plaque bacteria (in patients with poor oral hygiene care); and a poor fit of the prostheses to the soft tissues. Treatment of the infection must proceed in the following order: a) use of effective medication against oral fungus such as | 2635009 | [
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[Stomatitis from dentures: etiopathological and therapeutic considerations]. | Nystatin or Ketoconazole. b) Meticulous oral hygiene care in the mucous membrane as well as in the prostheses; but using the prostheses as little as possible during the treatment period. c) A total cure of the infection (denture stomatitis) before proceeding to the next phase of the treatment. d) Determination of the adjustment and occlusion of the prostheses in order to determine those areas of the prostheses which need to be refilled because of maladjustment of the prostheses to the soft tissues of the pa | 2635009 | [
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[Stomatitis from dentures: etiopathological and therapeutic considerations]. | tient. | 2635009 | [
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[Oral lesions in toxic epidermal necrolysis]. | In the oral mucosa it can be observed lesion produced by general disease. These; in some occasions help to obtained diagnosis; but in other it makes a lot of difficulties. We observed a patient with a toxic epidermal necrosis. His first signs were herpes oral lesions. We made a differential diagnosis with other dermatological process; and examined the possibilities in obtaining a diagnosis and the validity of the analytical data. | 2635010 | [
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[Treatment of dental agenesis in the child]. | This paper aims to emphasize the highly interdisciplinary nature of the relationship between the pedodontist; the orthodontist and the prosthodontist in monitoring and successfully dealing with the special cases of oral pathology represented by agenesis of the lateral incisors; with the possibility of creating space. The use of prosthetic appliances is all but mandatory in the treatment of agenesis of the upper lateral incisors. | 2635012 | [
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[Oral lymphomas in AIDS]. | We present two cases of AIDS in drug-addicts; with mouth lymphoma. The diagnosis was established by a gum biopsy which gave high-grade non-Hodgkin lymphoma lymphoblastic "B" type. It is very rare that the oral mucous is affected by lymphomas; but in AIDS and immunodeficiencies it is more common. | 2635011 | [
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[Diagnosis and surgical treatment of cystic granuloma]. | The survival therapy of cystic lesion with concomitant cystotomy and apicectomy permits the healing of the inflammatory process and the total restitution of the affected tissues. The diagnostic phase is fundamental; with identification of the cystic lesion for which removal is elective. | 2635013 | [
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[Laminar canals: identification and therapy]. | nan | 2635021 | [
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The effect of age of onset on depression in the elderly. | In an attempt to examine the effects of age and age of onset on depressive illness; the records of 55 psychiatric inpatients with an average age of 77 years were reviewed. There was no correlation between age and presence of psychosis; severe cognitive impairment; positive family history; length of hospitalization; treatment; or treatment response. When the cases were grouped on the basis of age of first admission; only the rates of family history were significantly different. Although age per se may have l | 2635015 | [
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The effect of age of onset on depression in the elderly. | ittle influence on the nature of depressive illness; age of onset may be important in distinguishing different types of depressive illness in the elderly; which suggests implications for treatment and prognosis. | 2635015 | [
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Assessment of disruptive behavior associated with dementia: the Disruptive Behavior Rating Scales. | Disruptive behavior associated with dementia is a major clinical problem; but there has been limited methodology for assessing it. This study describes the development of a set of rating scales used to measure four dimensions of disruptive behavior that present frequent problems in patients with dementia: physical aggression; verbal aggression; agitation; and wandering. In addition; a total disruptive behavior scale is derived by averaging scores from these four scales. A sample of 16 patients in a skilled | 2635016 | [
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Assessment of disruptive behavior associated with dementia: the Disruptive Behavior Rating Scales. | nursing facility was used to test interrater reliability and validity of this instrument. Interrater reliability was quite favorable for all scales. There was clear evidence for convergent validity of all scales except the verbal aggression scale; where a substantial correlation was found with one relevant external measure but not the other. There was also favorable evidence of discriminant validity for all scales except the verbal aggression scale. Psychometric properties of this instrument appear to be pr | 2635016 | [
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Personality alterations in dementia of the Alzheimer type: a three-year follow-up study. | Alterations in personality accompany the onset and progression of dementia of the Alzheimer type. Longitudinal investigations of these changes using systematic quantifiable documentation have been infrequent. In this 3-year follow-up study; we report longitudinal observations of changes in personality in dementia of the Alzheimer type. Four response patterns were observed: (1) change at onset with little change as the disease continued; (2) ongoing change as the disorder progressed; (3) no change; and (4) r | 2635017 | [
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Personality alterations in dementia of the Alzheimer type: a three-year follow-up study. | egression of previously more disturbed behaviors. Repeated characterizations of the premorbid personality profile as determined by this inventory were found to be reliable. | 2635017 | [
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Amino acid levels in elderly nursing home residents. | We have compared levels of albumin and serum amino acids in a group of 87 recent admissions to a nursing home; average age 83 years; with a group of healthy moderately old subjects; average age 69 years. We found that the nursing home group was characterized by decreased levels of albumin; by increased total levels of the measured amino acids; and by increased levels of the nonessential amino acids. In contrast; there were no significant group differences in the essential amino acids. Among the nursing home | 2635018 | [
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Amino acid levels in elderly nursing home residents. | patients; there was a negative correlation between essential amino acids and disability; consistent with nutritional deficits in the more disabled patients; and a positive correlation between essential amino acids and subjective complaints of pain; suggesting that pain is associated with breakdown or mobilization of endogenous protein stores. Though the nursing home patients had decreased serum levels of tryptophan; there was no association between serum tryptophan or other variables that could be related | 2635018 | [
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Amino acid levels in elderly nursing home residents. | to the availability of tryptophan for transport into brain; with ratings of either depression or pain. Glutamine levels were significantly increased in the nursing home residents; and among these patients they were positively correlated with measures of cognitive impairment. | 2635018 | [
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Two more cases of trazodone-related syncope in the elderly. | nan | 2635019 | [
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