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Please translate the following sentences from Chinese to English.
结直肠癌肝转移转化治疗的研究进展。结直肠癌患者在全病程中发生肝转移的概率达40%~50%,肝转移是影响结直肠癌患者长期预后的重要不利因素。手术切除肝转移灶是唯一可能达到近似根治效果的治疗选择。对于判断为不可切除的肝转移灶,经过综合治疗,使肿瘤缩小,进而将初始不可切除病灶转化为可切除病灶,称为转化治疗。转化治疗可分为以化疗±靶向为主的系统治疗及局部治疗。本文重点综述近年来结直肠癌肝转移转化治疗相关研究成果:(1)梳理肝转移癌手术可切除性评估标准;(2)探讨疗效评估、手术时机及肿瘤侧性对转化治疗方案选择的影响等临床问题;(3)总结转化治疗方案新进展,包括经典双药方案、三药联合的加强方案、分子靶向药物、免疫检查点抑制剂、多种局部疗法以及门静脉栓塞/两步肝切除、联合肝脏分割和门静脉结扎的分步肝切除术在转化治疗中的应用效果。本综述通过分析结直肠癌肝转移转化治疗现有问题,以期为结直肠癌肝转移的临床治疗发展提供参考。
Research progress of conversion therapy in colorectal cancer liver metastases. The probability of developing liver metastases in patients with colorectal cancer is 40%-50%. Liver metastases remain an important adverse factor affecting long-term prognosis of colorectal cancer patients. Surgical resection of liver metastases is the only potentially curative treatment option. After comprehensive treatment, initially unresectable liver metastases might be converted to resectable tumors. This concept is known as conversion therapy. In this review, research status of conversion therapy in colorectal cancer liver metastases was summarized, providing updated concept of resectability, discussions on the assessment of tumor response and timing of operation, debates on the influence on tumor sidedness, and latest advancement in the treatment strategy of conversion therapy. Through analyzing existing problems, we hope to offer insights into possible progress in the future and provide references for the development of clinical practice.
Please translate the following sentences from English to Chinese.
Research progress of conversion therapy in colorectal cancer liver metastases. The probability of developing liver metastases in patients with colorectal cancer is 40%-50%. Liver metastases remain an important adverse factor affecting long-term prognosis of colorectal cancer patients. Surgical resection of liver metastases is the only potentially curative treatment option. After comprehensive treatment, initially unresectable liver metastases might be converted to resectable tumors. This concept is known as conversion therapy. In this review, research status of conversion therapy in colorectal cancer liver metastases was summarized, providing updated concept of resectability, discussions on the assessment of tumor response and timing of operation, debates on the influence on tumor sidedness, and latest advancement in the treatment strategy of conversion therapy. Through analyzing existing problems, we hope to offer insights into possible progress in the future and provide references for the development of clinical practice.
结直肠癌肝转移转化治疗的研究进展。结直肠癌患者在全病程中发生肝转移的概率达40%~50%,肝转移是影响结直肠癌患者长期预后的重要不利因素。手术切除肝转移灶是唯一可能达到近似根治效果的治疗选择。对于判断为不可切除的肝转移灶,经过综合治疗,使肿瘤缩小,进而将初始不可切除病灶转化为可切除病灶,称为转化治疗。转化治疗可分为以化疗±靶向为主的系统治疗及局部治疗。本文重点综述近年来结直肠癌肝转移转化治疗相关研究成果:(1)梳理肝转移癌手术可切除性评估标准;(2)探讨疗效评估、手术时机及肿瘤侧性对转化治疗方案选择的影响等临床问题;(3)总结转化治疗方案新进展,包括经典双药方案、三药联合的加强方案、分子靶向药物、免疫检查点抑制剂、多种局部疗法以及门静脉栓塞/两步肝切除、联合肝脏分割和门静脉结扎的分步肝切除术在转化治疗中的应用效果。本综述通过分析结直肠癌肝转移转化治疗现有问题,以期为结直肠癌肝转移的临床治疗发展提供参考。
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具有快速动态响应的三态功率因数校正变换器
Tri-state Boost PFC converter with fast dynamic response
Please translate the following sentences from English to Chinese.
Tri-state Boost PFC converter with fast dynamic response
具有快速动态响应的三态功率因数校正变换器
Please translate the following sentences from Chinese to English.
肺癌的影像学分期。肺癌的分期明确了病变的范围,正确的分期对决定能否手术、选择治疗方法和预测预后都十分重要。本文介绍了新修订的国际抗癌协会(UICC)1997年肺癌分期法,包括TNM分期和临床分期,影像学方法是用于患者分期中的最重要的无创伤性技术,胸部和上腹部CT是其中的标准检查方法。本文详细叙述了CT在肺癌分期中的价值及其不足之处,其中主要描述了邻近结构的肺癌侵犯和淋巴结转移的影像表现。MRI在诊断肺上沟癌和纵隔受累上较CT为优。PET有望在将来成为分期中的优良技术。
Staging of Lung Cancer with Imaging. The staging of lung cancer defines the extent of disease.Accurate staging is important to the selection of treatment regmens and prediction of the prognosis. The new revised staging method of lung cancer (1997, UICC) is introduced in this article. Imaging is the most importart noninvasive technique for lung cancer staging. The standard imaging technique for the staging of lung cancer is CT examination of chest and upper abdomen. The imaging appearences of neighboring structures' invasion and lymph node metastasis have been described. The merits and limits of CT in the staging of lung cancer are discussed in details. The role of MRI is limited, however, for the demonstration of superior sulcus tumor and mediastinal involvement MRI is better than CT. It may be proved ultimately that PET will be a good technique for lung cancer staging in the future.
Please translate the following sentences from English to Chinese.
Staging of Lung Cancer with Imaging. The staging of lung cancer defines the extent of disease.Accurate staging is important to the selection of treatment regmens and prediction of the prognosis. The new revised staging method of lung cancer (1997, UICC) is introduced in this article. Imaging is the most importart noninvasive technique for lung cancer staging. The standard imaging technique for the staging of lung cancer is CT examination of chest and upper abdomen. The imaging appearences of neighboring structures' invasion and lymph node metastasis have been described. The merits and limits of CT in the staging of lung cancer are discussed in details. The role of MRI is limited, however, for the demonstration of superior sulcus tumor and mediastinal involvement MRI is better than CT. It may be proved ultimately that PET will be a good technique for lung cancer staging in the future.
肺癌的影像学分期。肺癌的分期明确了病变的范围,正确的分期对决定能否手术、选择治疗方法和预测预后都十分重要。本文介绍了新修订的国际抗癌协会(UICC)1997年肺癌分期法,包括TNM分期和临床分期,影像学方法是用于患者分期中的最重要的无创伤性技术,胸部和上腹部CT是其中的标准检查方法。本文详细叙述了CT在肺癌分期中的价值及其不足之处,其中主要描述了邻近结构的肺癌侵犯和淋巴结转移的影像表现。MRI在诊断肺上沟癌和纵隔受累上较CT为优。PET有望在将来成为分期中的优良技术。
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木质家具自动喷漆机机械臂的设计及动力学仿真
Design and dynamic simulation of mechanical arm of automatic wood painting machine
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Design and dynamic simulation of mechanical arm of automatic wood painting machine
木质家具自动喷漆机机械臂的设计及动力学仿真
Please translate the following sentences from Chinese to English.
质量成就卓越--第二届国际电子质量论坛述评
Outstanding Performance is Established by Quality---Review of 2nd "International Forum for Electronic Quality"
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Outstanding Performance is Established by Quality---Review of 2nd "International Forum for Electronic Quality"
质量成就卓越--第二届国际电子质量论坛述评
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大粒径碎石桩加固超软弱土河道边坡的现场试验。本文介绍了用大粒径碎石桩加固不排水强度低于20 kPa的超软弱河道边坡的施工方法,碎石桩单桩和复合地基的检测内容和检测方法.提供了由测试数据获得的抗剪强度指标与面积置换率的关系、充盈系数与密实电流和留振时间的关系.用实测碎石桩复合地基抗剪强度计算了施工期边坡稳定安全系数,其结果满足规范要求.工程实例表明大粒径碎石桩加固人工河堤淤泥土层是成功的.
Field experiment of large-size gravel columns for reinforcement of very soft river slope. The construction and quality inspection method for large-size gravel columns reinforcing the very soft river slope are introduced.The relation between shear strength and area replacement ratio,relation between over-charged coefficient and load current,as well as the load time are obtained from field experiments.The safety factor of a canal slope under construction is calculated by using the shear strength obtained from experiments and is in accord with the need of code.
Please translate the following sentences from English to Chinese.
Field experiment of large-size gravel columns for reinforcement of very soft river slope. The construction and quality inspection method for large-size gravel columns reinforcing the very soft river slope are introduced.The relation between shear strength and area replacement ratio,relation between over-charged coefficient and load current,as well as the load time are obtained from field experiments.The safety factor of a canal slope under construction is calculated by using the shear strength obtained from experiments and is in accord with the need of code.
大粒径碎石桩加固超软弱土河道边坡的现场试验。本文介绍了用大粒径碎石桩加固不排水强度低于20 kPa的超软弱河道边坡的施工方法,碎石桩单桩和复合地基的检测内容和检测方法.提供了由测试数据获得的抗剪强度指标与面积置换率的关系、充盈系数与密实电流和留振时间的关系.用实测碎石桩复合地基抗剪强度计算了施工期边坡稳定安全系数,其结果满足规范要求.工程实例表明大粒径碎石桩加固人工河堤淤泥土层是成功的.
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科研机构转制中存在的问题及对策
Solutions to Problems in Transition of Mechanism of S&T Research Institutions
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Solutions to Problems in Transition of Mechanism of S&T Research Institutions
科研机构转制中存在的问题及对策
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氟喹诺酮C-3羧基等排体的合成及抗肿瘤活性:均三唑-(口恶)二唑甲硫醚曼尼希碱衍生物
Synthesis and antitumor activities of fluoroquinolone C-3 isosteres(Ⅳ) : s-triazole-oxadiazole methylsulfide Mannich-base derivatives
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Synthesis and antitumor activities of fluoroquinolone C-3 isosteres(Ⅳ) : s-triazole-oxadiazole methylsulfide Mannich-base derivatives
氟喹诺酮C-3羧基等排体的合成及抗肿瘤活性:均三唑-(口恶)二唑甲硫醚曼尼希碱衍生物
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一种混合内存系统访存热点控制方法。相变内存(Phase-Change Memory ,PCM )被认为是最有可能取代DRAM 的非挥发存储器件,它与DRAM读取性能相当且无需动态刷新,但存在着读写非对称和寿命受限的问题,因此在设计新型计算机系统存储结构时被考虑与DRAM 共同构建内存子系统。针对PCM-DRAM 平面混合内存架构中由于访存局部性所引起的热点区域集中读写访问所带来的不利影响,提出了一种基于访存热点控制的有效策略,来降低内存系统功耗和增加PCM使用寿命。
Efficient Management with Hotspots Control for Hybrid Memory System. As a popular Non-Volatile Memory technology ,Phase-Change Memory (PCM) is considering as the most potential candidate for DRAM due to its comparable read latency with DRAM ,high capacity and low idle power . But hybrid memory architecture which consists of both PCM and DRAM is suggested due to asymmetric read-write and limited endurance of PCM device .In this paper ,we propose an efficient management with hotspots controlling to reduce power consumption and improve PCM lifetime for PCM-DRAM flat hybrid main memory system to avoid the dense read or w rite access to memory hotspots caused by locality .
Please translate the following sentences from English to Chinese.
Efficient Management with Hotspots Control for Hybrid Memory System. As a popular Non-Volatile Memory technology ,Phase-Change Memory (PCM) is considering as the most potential candidate for DRAM due to its comparable read latency with DRAM ,high capacity and low idle power . But hybrid memory architecture which consists of both PCM and DRAM is suggested due to asymmetric read-write and limited endurance of PCM device .In this paper ,we propose an efficient management with hotspots controlling to reduce power consumption and improve PCM lifetime for PCM-DRAM flat hybrid main memory system to avoid the dense read or w rite access to memory hotspots caused by locality .
一种混合内存系统访存热点控制方法。相变内存(Phase-Change Memory ,PCM )被认为是最有可能取代DRAM 的非挥发存储器件,它与DRAM读取性能相当且无需动态刷新,但存在着读写非对称和寿命受限的问题,因此在设计新型计算机系统存储结构时被考虑与DRAM 共同构建内存子系统。针对PCM-DRAM 平面混合内存架构中由于访存局部性所引起的热点区域集中读写访问所带来的不利影响,提出了一种基于访存热点控制的有效策略,来降低内存系统功耗和增加PCM使用寿命。
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X-ray成像技术表征金属凝固组织及其演化过程研究进展
Application of Synchrotron X-ray Imaging in Solidification of Metallic Materials
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Application of Synchrotron X-ray Imaging in Solidification of Metallic Materials
X-ray成像技术表征金属凝固组织及其演化过程研究进展
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大型公立医院高级职称医师流动视角下的医师多点执业政策分析
Analysis on the Policy of Multi-site Physician Practice Based on the Mobility of Physicians with Senior Professional Titles in Major Public Hospitals
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Analysis on the Policy of Multi-site Physician Practice Based on the Mobility of Physicians with Senior Professional Titles in Major Public Hospitals
大型公立医院高级职称医师流动视角下的医师多点执业政策分析
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大振幅非定常实验数据表达与数学模型研究
Study of Data Expression and Mathematical Modelling for Unsteady Experiment of a Model Pitching in Large Amplitude
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Study of Data Expression and Mathematical Modelling for Unsteady Experiment of a Model Pitching in Large Amplitude
大振幅非定常实验数据表达与数学模型研究
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分布式文件系统性能研究。随着海量数据存储和I/O密集型应用的发展,I/O越发成为了分布式存储系统的性能瓶颈,分布式文件系统是解决I/O瓶颈问题的重要途径。如何系统地研究分布式文件系统的性能因子和优化方案,是一个重要研究课题。本文系统地阐述了分布式文件系统的性能研究现状,挖掘并分析了分布式文件系统的关键性能影响因子,为分布式文件系统的设计和性能优化研究提供支持。
Research on the Performance of Distributed File System. With the development of mass data storage and I/O intensive applications , I/O increasingly becomes the perform-ance bottleneck of distributed storage system and the distributed file system is the important way to solve the problem of I /O bottle-neck.How to systematically study the performance factor and optimize scheme of the distributed file system is an important research topic.This paper systematically elaborates the referred performance research of the distributed file system , analyzing the key per-formance impact factors of the distributed file system , and providing the design and performance optimization research of distributed file system.
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Research on the Performance of Distributed File System. With the development of mass data storage and I/O intensive applications , I/O increasingly becomes the perform-ance bottleneck of distributed storage system and the distributed file system is the important way to solve the problem of I /O bottle-neck.How to systematically study the performance factor and optimize scheme of the distributed file system is an important research topic.This paper systematically elaborates the referred performance research of the distributed file system , analyzing the key per-formance impact factors of the distributed file system , and providing the design and performance optimization research of distributed file system.
分布式文件系统性能研究。随着海量数据存储和I/O密集型应用的发展,I/O越发成为了分布式存储系统的性能瓶颈,分布式文件系统是解决I/O瓶颈问题的重要途径。如何系统地研究分布式文件系统的性能因子和优化方案,是一个重要研究课题。本文系统地阐述了分布式文件系统的性能研究现状,挖掘并分析了分布式文件系统的关键性能影响因子,为分布式文件系统的设计和性能优化研究提供支持。
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CFRP预应力筋夹片式锚具设计
Design of Wedge - type Anchors for CFRP Tendons
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Design of Wedge - type Anchors for CFRP Tendons
CFRP预应力筋夹片式锚具设计
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关于建设广东省信用安全环境的建议
Proposals for Building a Credit Security Environment in Guangdong
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Proposals for Building a Credit Security Environment in Guangdong
关于建设广东省信用安全环境的建议
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人脐带间充质干细胞对大鼠肺泡巨噬细胞表达细胞因子的影响
Effects of the Human Umbilical Cord Mesenchymal Stem Cells Pretreatment on the Expression of Inflammatory Cytokines in Macrophages
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Effects of the Human Umbilical Cord Mesenchymal Stem Cells Pretreatment on the Expression of Inflammatory Cytokines in Macrophages
人脐带间充质干细胞对大鼠肺泡巨噬细胞表达细胞因子的影响
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无氧铜杆炉微机控制系统
Microcomputer Control System for No Oxygen Copper Rod Furnace
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Microcomputer Control System for No Oxygen Copper Rod Furnace
无氧铜杆炉微机控制系统
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作物秸秆栽培榆黄菇
Cultivation of Pleurotuscitrinopileatus with crop straw
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Cultivation of Pleurotuscitrinopileatus with crop straw
作物秸秆栽培榆黄菇
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微波硫灯灯泡的研制
Development of Microwave Sulfur Lamp Bulb
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Development of Microwave Sulfur Lamp Bulb
微波硫灯灯泡的研制
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煤中多组分混合气体竞争吸附研究现状及工程应用
Research status and engineering application of competitive adsorption of multicomponent mixed gases in coal
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Research status and engineering application of competitive adsorption of multicomponent mixed gases in coal
煤中多组分混合气体竞争吸附研究现状及工程应用
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陕南地方性砷中毒病区人群尿中不同化学形态砷含量调查。目的 了解陕南地方性砷中毒病区暴露人群尿中不同化学形态砷含量和总砷(total arsenic,TAs)含量以及与砷中毒的关系.方法 根据砷中毒调查历史资料,选择陕南安康市的紫阳、平利2个县的11个病区村作为调查点,选择与其邻近且自然环境与生活习惯相近的非病区白河县的3个村镇作为对照点.在调查点分采暖及非采暖两季,抽取40岁以上人群做流行病学调查,然后按病情分层,每季每层收集尿样约40份;对照点抽取40岁以上人群,两季分别收集尿样约20份.采用氢化物发生-原子荧光法(HG-AFS)测定TAs,液相色谱-氢化物发生-原子荧光法(LC-HG-AFS)测定无机3价砷(As3+)、二甲基砷(DMA)、一甲基砷(MMA)和无机5价砷(As5+),对不同地区、病情、年龄、性别、季节的人群尿中不同化学形态砷和TAs含量进行比较.结果 病区人群尿中总TAs、As3+、DMA、一甲基化率(PMI)、二甲基化率(SMI)的中位数(35.3、2.2、24.5 μg/L,0.84、0.90)显著高于对照人群(16.0、0.6、10.3 μg/L,0.78、0.81;Z=-9.069、-7.314、-8.913、-2.183、-3.853;P< 0.01或<0.05),且病区正常人群尿中TAs、As3+、DMA、SMI(31.6、2.0、23.1 μg/L,0.91)也显著高于对照人群(Z=-7.164、-6.136、-7.023、-2.916,P均<0.01).砷中毒病情与TAs、DMA、年龄呈正相关关系(r=0.370、0.367、0.594,P均<0.01).男性砷中毒检出率、TAs、As3+、DMA(59.9%,37.4,2.5、25.2 μg/L)明显高于女性(22.4%,30.0、1.6、20.9 μg/L;x2=54.878,P<0.01;Z=-3.332、-4.449、-2.681,P均<0.01).采暖季As3+、MMA、As5+、PMI、SMI(1.5、2.1、1.4 μg/L,0.87、0.92)与非采暖季(2.6、3.3、3.0μg/L,0.82、0.88)比较差异有统计学意义(Z=-6.870、-5.512、-8.542、-2.262、-4.544,P< 0.01或<0.05).结论 人群尿样中TAs、As3+、DMA含量与当地砷含量有关,在病区的确定上有一定的参考意义.男性与女性比较,为较高的砷中毒易感人群.
An investigation on arsenide valence and speciation in urine of people in the endemic arsenism areas in the south of Shaanxi Province. Objective To investigate the urinary arsenic levels of exposed population in various forms of and total arsenic (TAs) content as well as their relationship with arsenic poisoning in southern Shaanxi arsenic poisoning area.Methods According to the historical data of the investigation on arsenic poisoning,11 disease villages were chosen as survey sites in Ziyang and Pingli counties,Ankang city;three neighbor villages were chosen as control sites in Baihe.Baihe was a non-endemic arsenic poisoning area county,which had the same natural environment and living habits.In the survey sites,people over the age of 40 were selected for epidemiological investigation in both heating and non-heating seasons,and 40 urine samples were collected at each severity levels of the disease and in different seasons.Meantime,20 urine samples of the same age group were collected in the control sites in each season.Hydride generation-atomic fluorescence spectrometry (HG-AFS) was used to determine TAs,liquid chromatography-hydride generation-atomic fluorescence spectrometry (LC-HG-AFS) was used to determine the amount of inorganic trivalent arsenic (As3+),dimethylarsine (DMA),monomethylarsine (MMA) and inorganic pentavalent arsenic (AS5+),and the various forms and TAs were compared between different survey sites,severity levels,ages,sexes,and seasons.Results The medians of TAs,As3+,DMA,primary methylation index (PMI),and secondary methylation index (SMI) in diseased area (35.3,2.2,24.5 μg/L;0.84,0.90) were significantly higher than those of the control group (16.0,0.6,10.3 μg/L;0.78,0.81;Z =-9.069,-7.314,-8.913,-2.183,-3.853,P < 0.01 or < 0.05),and the medians of TAs,As3+,DMA,and SMI (31.6,2.0,23.1 μg/L;0.91) of the normal population in the diseased area were significantly higher than those of the control group (16.0,0.6,10.3 μg/L;0.81;Z =-7.164,-6.136,-7.023,-2.916,all P < 0.01).Illness had positive correlations with TAs,DMA,and ages (r =0.370,0.367,0.594,all P < 0.01).Men arsenic poisoning detection rate,TAs,As3+,and DMA (59.9%,37.4,2.5,25.2 μg/L) were significantly higher than those of women (22.4%,30.0,1.6,20.9 μg/L;x2 =54.878,P < 0.01;Z =-3.332,-4.449,-2.681,all P < 0.01).The medians of As3+,MMA,As5+,PMI,and SMI in the heating season (1.5,2.1,1.4 μg/L;0.87,0.92) were significantly different from those in the non-heating season (2.6,3.3,3.0 μg/L;0.82,0.88;Z =-6.870,-5.512,-8.542,-2.262,-4.544,P < 0.01 or < 0.05).Conclusions The TAs,As3+,and DMA of urine samples are related to local arsenic background,so they have some reference value for determination of diseased areas.Men are more susceptible to arsenic poisoning than women.
Please translate the following sentences from English to Chinese.
An investigation on arsenide valence and speciation in urine of people in the endemic arsenism areas in the south of Shaanxi Province. Objective To investigate the urinary arsenic levels of exposed population in various forms of and total arsenic (TAs) content as well as their relationship with arsenic poisoning in southern Shaanxi arsenic poisoning area.Methods According to the historical data of the investigation on arsenic poisoning,11 disease villages were chosen as survey sites in Ziyang and Pingli counties,Ankang city;three neighbor villages were chosen as control sites in Baihe.Baihe was a non-endemic arsenic poisoning area county,which had the same natural environment and living habits.In the survey sites,people over the age of 40 were selected for epidemiological investigation in both heating and non-heating seasons,and 40 urine samples were collected at each severity levels of the disease and in different seasons.Meantime,20 urine samples of the same age group were collected in the control sites in each season.Hydride generation-atomic fluorescence spectrometry (HG-AFS) was used to determine TAs,liquid chromatography-hydride generation-atomic fluorescence spectrometry (LC-HG-AFS) was used to determine the amount of inorganic trivalent arsenic (As3+),dimethylarsine (DMA),monomethylarsine (MMA) and inorganic pentavalent arsenic (AS5+),and the various forms and TAs were compared between different survey sites,severity levels,ages,sexes,and seasons.Results The medians of TAs,As3+,DMA,primary methylation index (PMI),and secondary methylation index (SMI) in diseased area (35.3,2.2,24.5 μg/L;0.84,0.90) were significantly higher than those of the control group (16.0,0.6,10.3 μg/L;0.78,0.81;Z =-9.069,-7.314,-8.913,-2.183,-3.853,P < 0.01 or < 0.05),and the medians of TAs,As3+,DMA,and SMI (31.6,2.0,23.1 μg/L;0.91) of the normal population in the diseased area were significantly higher than those of the control group (16.0,0.6,10.3 μg/L;0.81;Z =-7.164,-6.136,-7.023,-2.916,all P < 0.01).Illness had positive correlations with TAs,DMA,and ages (r =0.370,0.367,0.594,all P < 0.01).Men arsenic poisoning detection rate,TAs,As3+,and DMA (59.9%,37.4,2.5,25.2 μg/L) were significantly higher than those of women (22.4%,30.0,1.6,20.9 μg/L;x2 =54.878,P < 0.01;Z =-3.332,-4.449,-2.681,all P < 0.01).The medians of As3+,MMA,As5+,PMI,and SMI in the heating season (1.5,2.1,1.4 μg/L;0.87,0.92) were significantly different from those in the non-heating season (2.6,3.3,3.0 μg/L;0.82,0.88;Z =-6.870,-5.512,-8.542,-2.262,-4.544,P < 0.01 or < 0.05).Conclusions The TAs,As3+,and DMA of urine samples are related to local arsenic background,so they have some reference value for determination of diseased areas.Men are more susceptible to arsenic poisoning than women.
陕南地方性砷中毒病区人群尿中不同化学形态砷含量调查。目的 了解陕南地方性砷中毒病区暴露人群尿中不同化学形态砷含量和总砷(total arsenic,TAs)含量以及与砷中毒的关系.方法 根据砷中毒调查历史资料,选择陕南安康市的紫阳、平利2个县的11个病区村作为调查点,选择与其邻近且自然环境与生活习惯相近的非病区白河县的3个村镇作为对照点.在调查点分采暖及非采暖两季,抽取40岁以上人群做流行病学调查,然后按病情分层,每季每层收集尿样约40份;对照点抽取40岁以上人群,两季分别收集尿样约20份.采用氢化物发生-原子荧光法(HG-AFS)测定TAs,液相色谱-氢化物发生-原子荧光法(LC-HG-AFS)测定无机3价砷(As3+)、二甲基砷(DMA)、一甲基砷(MMA)和无机5价砷(As5+),对不同地区、病情、年龄、性别、季节的人群尿中不同化学形态砷和TAs含量进行比较.结果 病区人群尿中总TAs、As3+、DMA、一甲基化率(PMI)、二甲基化率(SMI)的中位数(35.3、2.2、24.5 μg/L,0.84、0.90)显著高于对照人群(16.0、0.6、10.3 μg/L,0.78、0.81;Z=-9.069、-7.314、-8.913、-2.183、-3.853;P< 0.01或<0.05),且病区正常人群尿中TAs、As3+、DMA、SMI(31.6、2.0、23.1 μg/L,0.91)也显著高于对照人群(Z=-7.164、-6.136、-7.023、-2.916,P均<0.01).砷中毒病情与TAs、DMA、年龄呈正相关关系(r=0.370、0.367、0.594,P均<0.01).男性砷中毒检出率、TAs、As3+、DMA(59.9%,37.4,2.5、25.2 μg/L)明显高于女性(22.4%,30.0、1.6、20.9 μg/L;x2=54.878,P<0.01;Z=-3.332、-4.449、-2.681,P均<0.01).采暖季As3+、MMA、As5+、PMI、SMI(1.5、2.1、1.4 μg/L,0.87、0.92)与非采暖季(2.6、3.3、3.0μg/L,0.82、0.88)比较差异有统计学意义(Z=-6.870、-5.512、-8.542、-2.262、-4.544,P< 0.01或<0.05).结论 人群尿样中TAs、As3+、DMA含量与当地砷含量有关,在病区的确定上有一定的参考意义.男性与女性比较,为较高的砷中毒易感人群.
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接枝淀粉作为固定化酶载体研究进展
Review on grafted starch as immobilized enzyme supporter
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Review on grafted starch as immobilized enzyme supporter
接枝淀粉作为固定化酶载体研究进展
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两类混合藤Copula模型的比较研究--基于外汇资产投资组合 VaR 的研究。本文以中国外汇市场上四种主要外汇资产的投资组合作为研究对象,基于 Pair Copula 高维建模思想,分别建立了两类能真实反映资产组合相关结构差异性的混合藤 Copula 模型,即混合 C 藤和混合 D 藤 Copula 模型。两类混合藤Copula 模型,对传统的藤 Copula 模型作了进一步的改进,是通过一定的选择标准,确定模型中每个 Pair Copula 函数的最优函数族,这样可以使得所建立的模型既能考虑资产组合维数的影响,又能捕捉到组合内部各资产相关结构的差异性。为了得到较优的风险分析模型,在实证研究中,将两类模型在资产组合 VaR 计算精度方面进行比较。
The Comparison Study of Two Types of Mixed Vines Copula Model--Based on the Analysis of VaR of a Portfolio. Two types of mixed vines copula model based on Pair Copula Constructions method was used to study a portfolio of four foreign exchange assets in Foreign Exchange Market of China. The models, namely mixed C and D vines Copula model, can reflect the differences of correlation structure of a portfolio realistically. And also the two types of mixed vines Copula models improve on traditional C and D vines method and choose the best families of copula functions for every Pair Copula by a rule. They not only can take into account of the impact of dimensions, but also can capture the difference of the correlation structure among portfolio factors. In order to obtain a better VaR analysis model, we compare the two types of vines Copula models in the aspect of the portfolio VaR calculation accuracy in empirical study.
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The Comparison Study of Two Types of Mixed Vines Copula Model--Based on the Analysis of VaR of a Portfolio. Two types of mixed vines copula model based on Pair Copula Constructions method was used to study a portfolio of four foreign exchange assets in Foreign Exchange Market of China. The models, namely mixed C and D vines Copula model, can reflect the differences of correlation structure of a portfolio realistically. And also the two types of mixed vines Copula models improve on traditional C and D vines method and choose the best families of copula functions for every Pair Copula by a rule. They not only can take into account of the impact of dimensions, but also can capture the difference of the correlation structure among portfolio factors. In order to obtain a better VaR analysis model, we compare the two types of vines Copula models in the aspect of the portfolio VaR calculation accuracy in empirical study.
两类混合藤Copula模型的比较研究--基于外汇资产投资组合 VaR 的研究。本文以中国外汇市场上四种主要外汇资产的投资组合作为研究对象,基于 Pair Copula 高维建模思想,分别建立了两类能真实反映资产组合相关结构差异性的混合藤 Copula 模型,即混合 C 藤和混合 D 藤 Copula 模型。两类混合藤Copula 模型,对传统的藤 Copula 模型作了进一步的改进,是通过一定的选择标准,确定模型中每个 Pair Copula 函数的最优函数族,这样可以使得所建立的模型既能考虑资产组合维数的影响,又能捕捉到组合内部各资产相关结构的差异性。为了得到较优的风险分析模型,在实证研究中,将两类模型在资产组合 VaR 计算精度方面进行比较。
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紫檀芪对2型糖尿病大鼠肾损伤的改善作用
Effects of pterostilbene on renal injury in type 2 diabetes mellitus rats
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Effects of pterostilbene on renal injury in type 2 diabetes mellitus rats
紫檀芪对2型糖尿病大鼠肾损伤的改善作用
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大型工程建设项目集成管理概念模型研究
Study on Integration Management Concept Model for Large Construction Projects
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Study on Integration Management Concept Model for Large Construction Projects
大型工程建设项目集成管理概念模型研究
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建德铜矿Ⅱ号矿体矿柱回采工艺研究
A research for the stope technology of pillar in NO.2 orebody of Jiande copper mine
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A research for the stope technology of pillar in NO.2 orebody of Jiande copper mine
建德铜矿Ⅱ号矿体矿柱回采工艺研究
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基于GC-MS结合化学计量学分析4种酱香型缺陷白酒挥发性成分差异
Analysis of Volatile Component Differences among Four Defective Baijiu of Maotai-flavor Based on GC-MS Combined with Chemometrics
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Analysis of Volatile Component Differences among Four Defective Baijiu of Maotai-flavor Based on GC-MS Combined with Chemometrics
基于GC-MS结合化学计量学分析4种酱香型缺陷白酒挥发性成分差异
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新时代中国农业现代化发展水平熵评价
Entropy Evaluation of the Development Level of Chinese Agricultural Modernization in the New Era
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Entropy Evaluation of the Development Level of Chinese Agricultural Modernization in the New Era
新时代中国农业现代化发展水平熵评价
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热力站日供热量神经网络预测模型比较与分析
Comparison and Analysis of Neural Network Prediction Models for Daily Heating Capacity of Heating Station
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Comparison and Analysis of Neural Network Prediction Models for Daily Heating Capacity of Heating Station
热力站日供热量神经网络预测模型比较与分析
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上市公司总经理更替与董事会特征的实证研究
CEO Turnover and the Board of Directors:Empirical Evidence from Listed Companies in China
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CEO Turnover and the Board of Directors:Empirical Evidence from Listed Companies in China
上市公司总经理更替与董事会特征的实证研究
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电感耦合等离子体质谱测定乙二胺二氯合钯给药后人横纹肌瘤细胞中钯的含量和分布
Determination of Hmnan Rhabdomyosarcoma Cellular Palladium Concentration and Distribution by Inductively Coupled Plasma Mass Spectrometry after Administration of Ethylenediamine Palladium (Ⅱ) Chloride
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Determination of Hmnan Rhabdomyosarcoma Cellular Palladium Concentration and Distribution by Inductively Coupled Plasma Mass Spectrometry after Administration of Ethylenediamine Palladium (Ⅱ) Chloride
电感耦合等离子体质谱测定乙二胺二氯合钯给药后人横纹肌瘤细胞中钯的含量和分布
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法兰克福学派现代性批判的理论路径
On Frankfurt School's Critique Theory of Modernity
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On Frankfurt School's Critique Theory of Modernity
法兰克福学派现代性批判的理论路径
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试论加大对行贿犯罪打击力度的反腐战略
On Strategey of Fighting corruption by Belittling Accept- bribes and Attaching Importance to Bribing
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On Strategey of Fighting corruption by Belittling Accept- bribes and Attaching Importance to Bribing
试论加大对行贿犯罪打击力度的反腐战略
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海洋环境下深水区立管腐蚀速率预测。为提升海洋环境下深水区立管腐蚀速率的预测精度,建立基于改进秃鹰搜索算法(Improved Bald Eagle Search,IBES)的EDGM(1,1,p)腐蚀速率预测模型.通过Sine混沌映射初始化种群、莱维飞行策略、折射反向学习策略和柯西高斯变异策略提高秃鹰搜索算法的寻优能力和收敛速度;利用IBES算法优化EDGM(1,1,p)中的参数p,建立IBES-EDGM(1,1,p)模型以提高立管腐蚀速率的预测精度.以南海某海洋深水区立管数据为基础进行腐蚀速率预测,分析对比3种模型的预测结果.结果表明,优化后的模型与原模型相比误差更小,且预测精度得到了提高,能够更准确地预测深海立管的腐蚀速率,为后续管道系统的维修和更换提供理论参考.
Prediction of corrosion rates of risers in deep water in the marine environment. Corrosion of oil and gas pipelines is a major cause of pipeline failure,and although research on corrosion prediction of buried and subsea pipelines is relatively mature,little research has been conducted on marine risers.In this paper,the corrosion of risers in deep water under a marine environment is studied.To improve the prediction accuracy of the corrosion rate of risers in deep water under the marine environment,an EDGM(1,1)corrosion rate prediction model based on an Improved Bald Eagle Search(IBES)algorithm is established.The initial population layout of the Bald Eagle Search(BES)algorithm is optimized by initializing the population with sine chaotic mapping to enhance the optimization capability.A Lévy flight strategy is used to optimize the problem of the population converging too early and falling into a local optimum when selecting spatial solutions for the Condor Search algorithm.To address the problem of the search algorithm falling into a local optimum late in the iteration,the refractive backward learning strategy and the Corsi-Gaussian variational strategy are used to optimize the search algorithm to improve the optimization capability and convergence speed of the Condor search algorithm.The IBES algorithm is used to optimize the parameter ρ in EDGM(1,1,ρ)to establish the IBES-EDGM(1,1,ρ)model to improve the prediction accuracy of the riser corrosion rate.The corrosion rate prediction was carried out based on riser data from a deep-water marine area in the South China Sea,and the prediction results of the three models were analyzed and compared.The results show that the IBES-EDGM(1,1,ρ)model has an EMAE of 0.030 7,ERMSE of0.009 8,and FD of 0.945 0,which are all better than the EDGM(1,1)and BES-EDGM(1,1,ρ)models.The constructed IBES-EDGM(1,1,ρ)model has less error and improved prediction accuracy compared to the conventional model and can predict the corrosion rate of deep-sea risers more accurately.In the absence of a large amount of corrosion data,this model can be used to predict the corrosion rate of key corrosion areas of risers in deep-sea areas,which can provide a theoretical reference for subsequent risk warning assessment and maintenance of marine pipeline systems.
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Prediction of corrosion rates of risers in deep water in the marine environment. Corrosion of oil and gas pipelines is a major cause of pipeline failure,and although research on corrosion prediction of buried and subsea pipelines is relatively mature,little research has been conducted on marine risers.In this paper,the corrosion of risers in deep water under a marine environment is studied.To improve the prediction accuracy of the corrosion rate of risers in deep water under the marine environment,an EDGM(1,1)corrosion rate prediction model based on an Improved Bald Eagle Search(IBES)algorithm is established.The initial population layout of the Bald Eagle Search(BES)algorithm is optimized by initializing the population with sine chaotic mapping to enhance the optimization capability.A Lévy flight strategy is used to optimize the problem of the population converging too early and falling into a local optimum when selecting spatial solutions for the Condor Search algorithm.To address the problem of the search algorithm falling into a local optimum late in the iteration,the refractive backward learning strategy and the Corsi-Gaussian variational strategy are used to optimize the search algorithm to improve the optimization capability and convergence speed of the Condor search algorithm.The IBES algorithm is used to optimize the parameter ρ in EDGM(1,1,ρ)to establish the IBES-EDGM(1,1,ρ)model to improve the prediction accuracy of the riser corrosion rate.The corrosion rate prediction was carried out based on riser data from a deep-water marine area in the South China Sea,and the prediction results of the three models were analyzed and compared.The results show that the IBES-EDGM(1,1,ρ)model has an EMAE of 0.030 7,ERMSE of0.009 8,and FD of 0.945 0,which are all better than the EDGM(1,1)and BES-EDGM(1,1,ρ)models.The constructed IBES-EDGM(1,1,ρ)model has less error and improved prediction accuracy compared to the conventional model and can predict the corrosion rate of deep-sea risers more accurately.In the absence of a large amount of corrosion data,this model can be used to predict the corrosion rate of key corrosion areas of risers in deep-sea areas,which can provide a theoretical reference for subsequent risk warning assessment and maintenance of marine pipeline systems.
海洋环境下深水区立管腐蚀速率预测。为提升海洋环境下深水区立管腐蚀速率的预测精度,建立基于改进秃鹰搜索算法(Improved Bald Eagle Search,IBES)的EDGM(1,1,p)腐蚀速率预测模型.通过Sine混沌映射初始化种群、莱维飞行策略、折射反向学习策略和柯西高斯变异策略提高秃鹰搜索算法的寻优能力和收敛速度;利用IBES算法优化EDGM(1,1,p)中的参数p,建立IBES-EDGM(1,1,p)模型以提高立管腐蚀速率的预测精度.以南海某海洋深水区立管数据为基础进行腐蚀速率预测,分析对比3种模型的预测结果.结果表明,优化后的模型与原模型相比误差更小,且预测精度得到了提高,能够更准确地预测深海立管的腐蚀速率,为后续管道系统的维修和更换提供理论参考.
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碳酸盐岩气藏储层物性下限确定方法研究现状及前景展望。碳酸盐岩气藏是中国天然气增储上产的重要领域,其储层物性下限的确定是勘探开发各个阶段的重要研究工作之一.目前国内确定碳酸盐岩气藏储层物性下限的方法零散,缺乏系统性,与实际矿场应用之间存在一定矛盾.针对这一问题,系统总结和扩展了储层物性下限的概念,提出储层物性下限系统研究新理念.新理念整合了岩心分析、测试分析和动态分析3类研究之间的关系,并分别论述了目前这3个方面各项方法的研究现状和存在问题.围绕碳酸盐岩气藏储层物性下限确定的需求和矛盾,提出系统研究储层物性下限的原则以及物性下限确定的系统性、不同井型和储层改造工艺对物性下限的影响、动态分析结果确定储层的物性下限值3个方面的研究建议,以期提升碳酸盐岩气藏储层物性下限研究的科学性、有效性和矿场应用的广泛性.
Research status and prospect of methods for determining the lower limit of reservoir physical properties in carbonate gas reservoirs. Carbonate gas reservoirs are an important field for increasing natural gas storage and production in China,and determining the lower limit of reservoir physical properties is an important research work in various stages of exploration and development.At present,the methods for determining the lower limit of reservoir phys-ical properties in carbonate gas reservoirs in China are scattered and lack systematicity,which contradicts the ac-tual application in mines.In response to this issue,this article systematically summarized and expanded the con-cept of the lower limit of reservoir physical properties,and proposed a new concept for the study of the lower lim-it system of reservoir physical properties.The new concept system integrated the relationship between core anal-ysis,testing analysis,and dynamic analysis,and discussed the current research status and existing problems of various methods in these three aspects.Focusing on the needs and contradictions of determining the lower limit of reservoir physical properties in carbonate gas reservoirs,this paper proposed three research suggestions:the principle of systematically studying the lower limit of reservoir physical properties,the systematicity of determin-ing the lower limit of physical properties,the impact of different well types and reservoir transformation process-es on the lower limit of physical properties,and the determination of the lower limit of reservoir physical proper-ties based on dynamic analysis results.The aim is to enhance the scientific and effective research of the lower limit of reservoir physical properties in carbonate gas reservoirs,as well as the universality of field applications.
Please translate the following sentences from English to Chinese.
Research status and prospect of methods for determining the lower limit of reservoir physical properties in carbonate gas reservoirs. Carbonate gas reservoirs are an important field for increasing natural gas storage and production in China,and determining the lower limit of reservoir physical properties is an important research work in various stages of exploration and development.At present,the methods for determining the lower limit of reservoir phys-ical properties in carbonate gas reservoirs in China are scattered and lack systematicity,which contradicts the ac-tual application in mines.In response to this issue,this article systematically summarized and expanded the con-cept of the lower limit of reservoir physical properties,and proposed a new concept for the study of the lower lim-it system of reservoir physical properties.The new concept system integrated the relationship between core anal-ysis,testing analysis,and dynamic analysis,and discussed the current research status and existing problems of various methods in these three aspects.Focusing on the needs and contradictions of determining the lower limit of reservoir physical properties in carbonate gas reservoirs,this paper proposed three research suggestions:the principle of systematically studying the lower limit of reservoir physical properties,the systematicity of determin-ing the lower limit of physical properties,the impact of different well types and reservoir transformation process-es on the lower limit of physical properties,and the determination of the lower limit of reservoir physical proper-ties based on dynamic analysis results.The aim is to enhance the scientific and effective research of the lower limit of reservoir physical properties in carbonate gas reservoirs,as well as the universality of field applications.
碳酸盐岩气藏储层物性下限确定方法研究现状及前景展望。碳酸盐岩气藏是中国天然气增储上产的重要领域,其储层物性下限的确定是勘探开发各个阶段的重要研究工作之一.目前国内确定碳酸盐岩气藏储层物性下限的方法零散,缺乏系统性,与实际矿场应用之间存在一定矛盾.针对这一问题,系统总结和扩展了储层物性下限的概念,提出储层物性下限系统研究新理念.新理念整合了岩心分析、测试分析和动态分析3类研究之间的关系,并分别论述了目前这3个方面各项方法的研究现状和存在问题.围绕碳酸盐岩气藏储层物性下限确定的需求和矛盾,提出系统研究储层物性下限的原则以及物性下限确定的系统性、不同井型和储层改造工艺对物性下限的影响、动态分析结果确定储层的物性下限值3个方面的研究建议,以期提升碳酸盐岩气藏储层物性下限研究的科学性、有效性和矿场应用的广泛性.
Please translate the following sentences from Chinese to English.
一种新型吲哚类荧光试剂的合成与荧光性质研究。设计并合成了一种新型吲哚类荧光试剂,并以红外光谱、高分辨质谱以及氢核磁共振图谱等手段表征了其结构。同时,结合其结构特点分析了该荧光试剂的荧光性质,为新型吲哚类荧光试剂的设计与合成提供了新思路。
Synthesis of a Novel Indole Fluorescent Reagent and Its Fluorescence Properties. A novel indole fluorescent reagent was designed and synthesized,IR,HRMS and 1H NMR were used to verify the structure. Furthermore,the fluorescence properties were studied and analyzed by combining with its structure characteristics,which provides new ideas for the design and synthesis of novel indole fluorescent reagents.
Please translate the following sentences from English to Chinese.
Synthesis of a Novel Indole Fluorescent Reagent and Its Fluorescence Properties. A novel indole fluorescent reagent was designed and synthesized,IR,HRMS and 1H NMR were used to verify the structure. Furthermore,the fluorescence properties were studied and analyzed by combining with its structure characteristics,which provides new ideas for the design and synthesis of novel indole fluorescent reagents.
一种新型吲哚类荧光试剂的合成与荧光性质研究。设计并合成了一种新型吲哚类荧光试剂,并以红外光谱、高分辨质谱以及氢核磁共振图谱等手段表征了其结构。同时,结合其结构特点分析了该荧光试剂的荧光性质,为新型吲哚类荧光试剂的设计与合成提供了新思路。
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脉动流化干燥机中脉冲气流发生器的机构设计
Mechanism design of pulser in pulsation flow desiccation machine
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Mechanism design of pulser in pulsation flow desiccation machine
脉动流化干燥机中脉冲气流发生器的机构设计
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基于模糊有限自动机的双模糊拓扑性质
Characterization of Bifuzzy Topology Based on Fuzzy Finite Automata
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Characterization of Bifuzzy Topology Based on Fuzzy Finite Automata
基于模糊有限自动机的双模糊拓扑性质
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从黄石三村看农村基层组织工作重心的转移
Transformation of Focus of Rural Grass-roots Organization in the Three Villages of Huangshi City
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Transformation of Focus of Rural Grass-roots Organization in the Three Villages of Huangshi City
从黄石三村看农村基层组织工作重心的转移
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髓核对大鼠脊神经节非压迫性损伤的组织形态学研究
Autologous nucleus pulposus induces histologic changes in rat spinal ganglion without mechanical compression
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Autologous nucleus pulposus induces histologic changes in rat spinal ganglion without mechanical compression
髓核对大鼠脊神经节非压迫性损伤的组织形态学研究
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D-box附近泛素化位点突变对Cdc20介导的Sp100蛋白降解的影响
Point Mutation of D-box Nearby Ubiquitin Binding Site Affect Cdc20 Mediated Sp100 Degradation
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Point Mutation of D-box Nearby Ubiquitin Binding Site Affect Cdc20 Mediated Sp100 Degradation
D-box附近泛素化位点突变对Cdc20介导的Sp100蛋白降解的影响
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定量检测牛雌性发育候选基因FOXL2表达方法的建立
Construction of Bovine Sex Related Genes FOXL2 Standard Plasmid and Standard Curve by Real-time RT-PCR
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Construction of Bovine Sex Related Genes FOXL2 Standard Plasmid and Standard Curve by Real-time RT-PCR
定量检测牛雌性发育候选基因FOXL2表达方法的建立
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颅内血肿微创穿刺清除技术的现状及展望
Status and Prospect of Microinvasive Craniopuncture Scavenging Technique for Intracranial Hemotoma
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Status and Prospect of Microinvasive Craniopuncture Scavenging Technique for Intracranial Hemotoma
颅内血肿微创穿刺清除技术的现状及展望
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数据中心高压冷水机组定性故障诊断模型构建
Construction of Qualitative Fault Diagnosis Model for Data Center High Voltage Chiller
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Construction of Qualitative Fault Diagnosis Model for Data Center High Voltage Chiller
数据中心高压冷水机组定性故障诊断模型构建
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教育装备学的发展与定位
The Development and Orientation of Education Equipment Science
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The Development and Orientation of Education Equipment Science
教育装备学的发展与定位
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清洁发展机制条件下林业可认证减排量成本价格的研究
Study on Forest Certified Emission Reduction Price under the Condition of Clean Development Machanism
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Study on Forest Certified Emission Reduction Price under the Condition of Clean Development Machanism
清洁发展机制条件下林业可认证减排量成本价格的研究
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河北平原生态环境用水量估算
Estimation of Eco-environmental Water Demand in Hebei Plain
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Estimation of Eco-environmental Water Demand in Hebei Plain
河北平原生态环境用水量估算
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凉山州彝族题材影视现状与发展对策分析
On the Situation and Development Strategies of Films with Yi Element in Liangshan Prefecture
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On the Situation and Development Strategies of Films with Yi Element in Liangshan Prefecture
凉山州彝族题材影视现状与发展对策分析
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论《铁木前传》的悲剧性
On the Tragic Color of Sun Li's The Early Story of Tiemu
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On the Tragic Color of Sun Li's The Early Story of Tiemu
论《铁木前传》的悲剧性
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现代远程教育平台技术综述
Overview of the System Platform Technologies in Modern Distance Education
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Overview of the System Platform Technologies in Modern Distance Education
现代远程教育平台技术综述